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Conserved domains on  [gi|688587761|ref|XP_009289920|]
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interleukin 15, like isoform X2 [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IL15 super family cl03560
Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological ...
 55-149 9.86e-04

Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological functions, including stimulation and maintenance of cellular immune responses. Structurally these proteins are short-chain 4-helical cytokines.


The actual alignment was detected with superfamily member pfam02372:

Pssm-ID: 308146  Cd Length: 129  Bit Score: 37.12  E-value: 9.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688587761   55 KQIAAKLNNVENDCMMYTPTQAnyKQNCSKSTITCFAFEVSVL---------SVEIQVESLaFRQLQRILNRVTKRDEME 125
Cdd:pfam02372  29 EIIENLINSIHIDATLYTESDT--HPECKVTALQCFLLELRVIlhesiedneEIKEEVENL-IINANSNLSSLQDLNPTE 105

                          90       100
                  ....*....|....*....|....
gi 688587761  126 MKCPVCELYKEESTKTFLNTLQHI 149
Cdd:pfam02372 106 SGCKECEELEEKNFPEFLQSFVHI 129
 
Name Accession Description Interval E-value
IL15 pfam02372
Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological ...
 55-149 9.86e-04

Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological functions, including stimulation and maintenance of cellular immune responses. Structurally these proteins are short-chain 4-helical cytokines.


Pssm-ID: 308146  Cd Length: 129  Bit Score: 37.12  E-value: 9.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688587761   55 KQIAAKLNNVENDCMMYTPTQAnyKQNCSKSTITCFAFEVSVL---------SVEIQVESLaFRQLQRILNRVTKRDEME 125
Cdd:pfam02372  29 EIIENLINSIHIDATLYTESDT--HPECKVTALQCFLLELRVIlhesiedneEIKEEVENL-IINANSNLSSLQDLNPTE 105

                          90       100
                  ....*....|....*....|....
gi 688587761  126 MKCPVCELYKEESTKTFLNTLQHI 149
Cdd:pfam02372 106 SGCKECEELEEKNFPEFLQSFVHI 129
 
Name Accession Description Interval E-value
IL15 pfam02372
Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological ...
 55-149 9.86e-04

Interleukin 15; Interleukin-15 (IL-15) is a cytokine that possesses a variety of biological functions, including stimulation and maintenance of cellular immune responses. Structurally these proteins are short-chain 4-helical cytokines.


Pssm-ID: 308146  Cd Length: 129  Bit Score: 37.12  E-value: 9.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688587761   55 KQIAAKLNNVENDCMMYTPTQAnyKQNCSKSTITCFAFEVSVL---------SVEIQVESLaFRQLQRILNRVTKRDEME 125
Cdd:pfam02372  29 EIIENLINSIHIDATLYTESDT--HPECKVTALQCFLLELRVIlhesiedneEIKEEVENL-IINANSNLSSLQDLNPTE 105

                          90       100
                  ....*....|....*....|....
gi 688587761  126 MKCPVCELYKEESTKTFLNTLQHI 149
Cdd:pfam02372 106 SGCKECEELEEKNFPEFLQSFVHI 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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