|
Name |
Accession |
Description |
Interval |
E-value |
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
157-286 |
5.56e-37 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 142.40 E-value: 5.56e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 157 KDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTP 236
Cdd:COG0666 77 GADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTP 156
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 672085415 237 LHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA---NSPTMVNLLLGKG 286
Cdd:COG0666 157 LHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAaenGHLEIVKLLLEAG 209
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
160-286 |
8.63e-37 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 142.02 E-value: 8.63e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHD 239
Cdd:COG0666 113 VNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHL 192
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 672085415 240 AANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA---NSPTMVNLLLGKG 286
Cdd:COG0666 193 AAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAaenGNLEIVKLLLEAG 242
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
160-274 |
7.54e-29 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 118.90 E-value: 7.54e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHD 239
Cdd:COG0666 146 VNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDL 225
|
90 100 110
....*....|....*....|....*....|....*
gi 672085415 240 AANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVAN 274
Cdd:COG0666 226 AAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAA 260
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
157-286 |
6.97e-28 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 116.21 E-value: 6.97e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 157 KDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTP 236
Cdd:COG0666 44 LLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETP 123
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 672085415 237 LHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA---NSPTMVNLLLGKG 286
Cdd:COG0666 124 LHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAaanGNLEIVKLLLEAG 176
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
171-263 |
1.39e-21 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 91.33 E-value: 1.39e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 171 LHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLA-AGAEVNTKGlddDTPLHDAANNGHYKVV 249
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEhADVNLKDNG---RTALHYAARSGHLEIV 77
|
90
....*....|....
gi 672085415 250 KLLLRYGGNPQQSN 263
Cdd:pfam12796 78 KLLLEKGADINVKD 91
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
160-270 |
2.64e-19 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 90.78 E-value: 2.64e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHD 239
Cdd:COG0666 179 VNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLL 258
|
90 100 110
....*....|....*....|....*....|.
gi 672085415 240 AANNGHYKVVKLLLRYGGNPQQSNRKGETPL 270
Cdd:COG0666 259 AAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
159-273 |
5.00e-18 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 89.64 E-value: 5.00e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 159 KVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLH 238
Cdd:PHA02874 116 DVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLH 195
|
90 100 110
....*....|....*....|....*....|....*
gi 672085415 239 DAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA 273
Cdd:PHA02874 196 NAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNA 230
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
731-1633 |
2.46e-16 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 86.35 E-value: 2.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 731 ERDRPSKTERERSTKEKSPKEEKlrlYKEERKKKSKDRPFKLEKkndMKEVSKEKEKAFREDKEKLKKEKLCRDDAAFDD 810
Cdd:PTZ00121 1070 EGLKPSYKDFDFDAKEDNRADEA---TEEAFGKAEEAKKTETGK---AEEARKAEEAKKKAEDARKAEEARKAEDARKAE 1143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 811 YCNKSQfldhEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDSVTDYRdiKSDSVAKLILETVKEDSKEKKRDNKTREK 890
Cdd:PTZ00121 1144 EARKAE----DAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVR--KAEELRKAEDARKAEAARKAEEERKAEEA 1217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 891 RDFRDSffrkRDRDCVDRNSEKRRDHTEKQRSFPSYLSEKDKKRRESAEGGRDRRDTLEGSRERR--DGRIRSEEVHR-E 967
Cdd:PTZ00121 1218 RKAEDA----KKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARkaDELKKAEEKKKaD 1293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 968 DLKEcgcdSTFKDKSDcdftktlepwERPHAAREKEKKDALEKDRKE-KGRAEKYKDKSGERERNEKSILEKCQKDKEFE 1046
Cdd:PTZ00121 1294 EAKK----AEEKKKAD----------EAKKKAEEAKKADEAKKKAEEaKKKADAAKKKAEEAKKAAEAAKAEAEAAADEA 1359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1047 KCFKEKKDGKEKHKDTHSKDRKTPFDQLREKKEKAFSSLISEDFSERKDDRKGKEKSWYIADiftdESEDEKEECVASSF 1126
Cdd:PTZ00121 1360 EAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD----EAKKKAEEKKKADE 1435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1127 KTGETGDSQRAESLQEKEDGREHPSDRHRKASSDRQHTEKPRDKEPKEKRKD-RGAAEGGKDKKEKIFEKHKEKKDKECA 1205
Cdd:PTZ00121 1436 AKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEaKKKAEEAKKKADEAKKAAEAKKKADEA 1515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1206 EKYKERKDRASVDSAPEKKNKQKLPEKVEKKHFVE-------DKAKSKHK-EKPEKDHSRERKSSRGPDVEKSLLEKLEE 1277
Cdd:PTZ00121 1516 KKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADElkkaeelKKAEEKKKaEEAKKAEEDKNMALRKAEEAKKAEEARIE 1595
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1278 EALHDYREDSNDKISEVSSDSFADHGQEpSLSTLLEVSFSEPPAEDKARESTCLSEKLKERERERHRHSSSSSKKSHERE 1357
Cdd:PTZ00121 1596 EVMKLYEEEKKMKAEEAKKAEEAKIKAE-ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1358 RAKKekadkkekgEDYKDGGGGRKDASQYEKDfadAEAFGGSYTTKADTEEDLDKAIELFSSEKKDRNDSER-----EPA 1432
Cdd:PTZ00121 1675 KKAE---------EAKKAEEDEKKAAEALKKE---AEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEakkeaEED 1742
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1433 KKLEKELKPYGSSTISILKEKKKREKHREKWREEKEKHRDKHIDGFLRHHKDEPKPAAKD-KDNPPNcFKEKSREESLKL 1511
Cdd:PTZ00121 1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDiFDNFAN-IIEGGKEGNLVI 1821
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1512 SEAKLKE--KFKE-----NAEREKGDSVKMSNGNDKPLPSRDANKKDSRPREKLLGDGDLmmtsfERMLSQKdlEIEERH 1584
Cdd:PTZ00121 1822 NDSKEMEdsAIKEvadskNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDE-----EEIEEAD--EIEKID 1894
|
890 900 910 920
....*....|....*....|....*....|....*....|....*....
gi 672085415 1585 KRHKERMKQMEKMRHRSGDpKLKEKKPTDDGRKKSLDFPSKKALGLDKK 1633
Cdd:PTZ00121 1895 KDDIEREIPNNNMAGKNND-IIDDKLDKDEYIKRDAEETREEIIKISKK 1942
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
204-286 |
3.43e-16 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 75.92 E-value: 3.43e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 204 LHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYggNPQQSNRKGETPLKVA---NSPTMVN 280
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH--ADVNLKDNGRTALHYAarsGHLEIVK 78
|
....*.
gi 672085415 281 LLLGKG 286
Cdd:pfam12796 79 LLLEKG 84
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
157-286 |
6.39e-15 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 78.07 E-value: 6.39e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 157 KDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTP 236
Cdd:COG0666 11 LLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTL 90
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 672085415 237 LHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA---NSPTMVNLLLGKG 286
Cdd:COG0666 91 LHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAaynGNLEIVKLLLEAG 143
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
657-1267 |
4.04e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 79.03 E-value: 4.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 657 KSFTYEYEDSKQKPDKAILLENDVSTENKLKVLKHDRDKLSKTKSEDKEWLFKDEKALKRMKDVSKDTSRAFREERDRPS 736
Cdd:PTZ00121 1105 KTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKA 1184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 737 KTER---ERSTKEKSPKEEKLRLYKEERKKKSKDR---PFKLEKKNDMKEVSKEKEKAFREDKEKLKKEKLCRDDAAFDD 810
Cdd:PTZ00121 1185 EEVRkaeELRKAEDARKAEAARKAEEERKAEEARKaedAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAH 1264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 811 YCNKSQFLDHEDTKFS--LSDDQQERWFSDLSDSSFDFKGEDSWDSVTDYRdiKSDSVAKLILETVKEDSKEKKRDNKTR 888
Cdd:PTZ00121 1265 FARRQAAIKAEEARKAdeLKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK--KADEAKKKAEEAKKKADAAKKKAEEAK 1342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 889 EKRDFRDSFFRKRDRDCvdRNSEKRRDHTEKQRSFPSYLSEKDKKRRESAEGGRDRRDTLEGSRERRDGRIRSEEVHR-- 966
Cdd:PTZ00121 1343 KAAEAAKAEAEAAADEA--EAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKka 1420
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 967 EDLKECGCDSTFKDKSDCDFTKTLEPWERPHAAREKEKKDALEKDRKEKGRAEKYKDKSGERERNE---KSILEKCQKDK 1043
Cdd:PTZ00121 1421 DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADeakKKAEEAKKKAD 1500
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1044 EFEKCFKEKKDGKEKHKDTHSK--------DRKTPFDQLR--EKKEKAFSSLISEDFSERKDDRKGKEKS-----WYIAD 1108
Cdd:PTZ00121 1501 EAKKAAEAKKKADEAKKAEEAKkadeakkaEEAKKADEAKkaEEKKKADELKKAEELKKAEEKKKAEEAKkaeedKNMAL 1580
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1109 IFTDESEDEKEECVASSFKTGETGDSQRAESLQEKEDGREHpSDRHRKASSDRQHTEKPRDKEPKEKRKD---RGAAEGG 1185
Cdd:PTZ00121 1581 RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK-AEELKKAEEEKKKVEQLKKKEAEEKKKAeelKKAEEEN 1659
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1186 KDKKEKIFEKhkekkdkecAEKYKERKDRASVDSAPEKKNKQKLPEKVEKKHFVEDKAKSKHKEKPEKDHSRERKSSRGP 1265
Cdd:PTZ00121 1660 KIKAAEEAKK---------AEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKI 1730
|
..
gi 672085415 1266 DV 1267
Cdd:PTZ00121 1731 KA 1732
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
160-286 |
6.29e-14 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 76.99 E-value: 6.29e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNERGETRLH---RAAIRGDARRIKELISEGADVNVKDFAGWTALH-EACNRGYYDIAKQLLAAGAEVNTKGLDDDT 235
Cdd:PHA03095 40 VNFRGEYGKTPLHlylHYSSEKVKDIVRLLLEAGADVNAPERCGFTPLHlYLYNATTLDVIKLLIKAGADVNAKDKVGRT 119
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 672085415 236 PLHD-AAN-NGHYKVVKLLLRYGGNPQQSNRKGETPLKV----AN-SPTMVNLLLGKG 286
Cdd:PHA03095 120 PLHVyLSGfNINPKVIRLLLRKGADVNALDLYGMTPLAVllksRNaNVELLRLLIDAG 177
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
709-1263 |
1.40e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.49 E-value: 1.40e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 709 KDEKALKRMKDVSKDTSRAFREERDRPSKTERER--------STKEKSPKEEKLRLYKEERKKKSKDRPFKLEKKNDMKE 780
Cdd:PTZ00121 1224 KKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFeearmahfARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKK 1303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 781 VSKEKEKAFREDKEKLKKEKLCRDDAAFDDYCNKSQfldhEDTKFSLSDDQQERWFSDLSDSSFDFKGEDswDSVTDYRD 860
Cdd:PTZ00121 1304 ADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAE----EAKKAAEAAKAEAEAAADEAEAAEEKAEAA--EKKKEEAK 1377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 861 IKSDSVAKLILETVKEDSKEKKRDNKTREKRDFRDSFFRKRDRDCVDRNSEKRRDHTE-KQRSFPSYLSEKDKKRRESAE 939
Cdd:PTZ00121 1378 KKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEaKKKAEEAKKADEAKKKAEEAK 1457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 940 GGRDRRDTLEGSRERRDGRIRSEEVHR-EDLKECGCDStfKDKSDcDFTKTLEPWERPHAAREKEKKDALEKDRKekgrA 1018
Cdd:PTZ00121 1458 KAEEAKKKAEEAKKADEAKKKAEEAKKaDEAKKKAEEA--KKKAD-EAKKAAEAKKKADEAKKAEEAKKADEAKK----A 1530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1019 EKYKDKSGERERNEKSILEKCQKDKEFEKCfKEKKDGKEKHKDTHSKD----RKTPFDQLREKKEKAFSSLISEDFSERK 1094
Cdd:PTZ00121 1531 EEAKKADEAKKAEEKKKADELKKAEELKKA-EEKKKAEEAKKAEEDKNmalrKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1095 DDRKGKEKSWYIADIFTDESEDEKEecvASSFKTGETGDSQRAESL-QEKEDGREHPSDRHRKASSDRQHTEKPRDKEPK 1173
Cdd:PTZ00121 1610 EEAKKAEEAKIKAEELKKAEEEKKK---VEQLKKKEAEEKKKAEELkKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEED 1686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1174 EKRKDRGAAEGGKDKKEKIFEKHKEKKDKECAEKYKERKDRASVDSAPEKKNKQKLPEKVEK-KHFVEDKAKSKHKEKPE 1252
Cdd:PTZ00121 1687 EKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEaKKDEEEKKKIAHLKKEE 1766
|
570
....*....|.
gi 672085415 1253 KDHSRERKSSR 1263
Cdd:PTZ00121 1767 EKKAEEIRKEK 1777
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
678-1539 |
2.26e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 76.72 E-value: 2.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 678 NDVSTENKLKVLKHDRDKLSKTKSEDKEWLFKDEKALKRMKDVSKDTSRAFREERdrpsKTERERSTKEKSPKEEKLRLY 757
Cdd:PTZ00121 1037 NNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADE----ATEEAFGKAEEAKKTETGKAE 1112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 758 KEERKKKSKDRP---FKLEKKNDMKEVSKEKEKAFREDKEKLKKEKLCRDDAAFDDYCNKSQFLDHEDTKFSLSDDQQE- 833
Cdd:PTZ00121 1113 EARKAEEAKKKAedaRKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEe 1192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 834 -RWFSDL--SDSSFDFKGEDSWDSVTDYRDIKSDSVAKLIlETVKEDSKEKKRDNKTR---EKRDFRDSFFRKRDRDCVD 907
Cdd:PTZ00121 1193 lRKAEDArkAEAARKAEEERKAEEARKAEDAKKAEAVKKA-EEAKKDAEEAKKAEEERnneEIRKFEEARMAHFARRQAA 1271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 908 ------RNSEKRRDHTEKQRSFPSYLSEKDKKRRESAEGGRDRRDTLEGSRERRDGRIRSEEVHREDLKECGCDSTFKDK 981
Cdd:PTZ00121 1272 ikaeeaRKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAE 1351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 982 SDCDFTKTLEPWERPHAAR-----EKEKKDALEKDRKEKGRAEKYKDKSgerERNEKSILEKCQKDKEFEKCFKEKKDGK 1056
Cdd:PTZ00121 1352 AEAAADEAEAAEEKAEAAEkkkeeAKKKADAAKKKAEEKKKADEAKKKA---EEDKKKADELKKAAAAKKKADEAKKKAE 1428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1057 EKHKDTHSKDRKTPFDQLREKKEKAFSSLISEDFSERKDDRKGkekswyiADIFTDESEDEKEecvASSFKTGETGDSQR 1136
Cdd:PTZ00121 1429 EKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK-------ADEAKKKAEEAKK---ADEAKKKAEEAKKK 1498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1137 AESLQEKEDGREHpSDRHRKASSDRQHTEKPRDKEPKEKRKDRGAAEGGKD---KKEKIFEKHKEKKDKECAEKYKERKD 1213
Cdd:PTZ00121 1499 ADEAKKAAEAKKK-ADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAdelKKAEELKKAEEKKKAEEAKKAEEDKN 1577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1214 RASVDSAPEKKNKQKLPEKVEKKHFVEDKAKSKHKEKPEKDHSRERKSSRGPDVEKSLLEKLEEEALHDYREDSNDKISE 1293
Cdd:PTZ00121 1578 MALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE 1657
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1294 VSSDSFADHGQ--EPSLSTLLEVSFSEppaEDKARESTCLSEKLKERERERHRHSSSSSKKSHERERAKKEKADKKEKGE 1371
Cdd:PTZ00121 1658 ENKIKAAEEAKkaEEDKKKAEEAKKAE---EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEE 1734
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1372 DYKDGGGGRKDASQYEKDFADAEAFGGSYTTKADTEEDLDKAIELFSSEKKDRNDSEREpaKKLEKELKPYGSSTISILK 1451
Cdd:PTZ00121 1735 AKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRR--MEVDKKIKDIFDNFANIIE 1812
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1452 EKKKREKHREKWREeKEKHRDKHIDGFLRHHKDEPKPAAKDKDNPPNCFKEKSREESLKLSEAKLKEKFKENAerEKGDS 1531
Cdd:PTZ00121 1813 GGKEGNLVINDSKE-MEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEI--EEADE 1889
|
....*...
gi 672085415 1532 VKMSNGND 1539
Cdd:PTZ00121 1890 IEKIDKDD 1897
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
179-287 |
5.30e-13 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 74.15 E-value: 5.30e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 179 DARRIKELISEGADVNVKD-FAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGG 257
Cdd:PHA02878 146 EAEITKLLLSYGADINMKDrHKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGA 225
|
90 100 110
....*....|....*....|....*....|....
gi 672085415 258 NPQQSNRKGETPLKVANSP----TMVNLLLGKGT 287
Cdd:PHA02878 226 STDARDKCGNTPLHISVGYckdyDILKLLLEHGV 259
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
128-286 |
9.88e-13 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 73.94 E-value: 9.88e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 128 SANSPD---TTP-KHPSQSTVCQKGTPNSASKTKDkVNKRNERGETRLHRAAIRG-DARRIKELISEGADVNVKDFAGWT 202
Cdd:PHA02876 265 SVNSIDdckNTPlHHASQAPSLSRLVPKLLERGAD-VNAKNIKGETPLYLMAKNGyDTENIRTLIMLGADVNAADRLYIT 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 203 ALHEACNRGYY-DIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA----NSPT 277
Cdd:PHA02876 344 PLHQASTLDRNkDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFAlcgtNPYM 423
|
....*....
gi 672085415 278 MVNLLLGKG 286
Cdd:PHA02876 424 SVKTLIDRG 432
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
160-286 |
1.15e-12 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 72.78 E-value: 1.15e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNERGETRLHRAAIR--GDARRIKELISEGADVNVKDFAGWTALHEA--CNRGYYDIAKQLLAAGAEVN-------- 227
Cdd:PHA03100 99 VNAPDNNGITPLLYAISKksNSYSIVEYLLDNGANVNIKNSDGENLLHLYleSNKIDLKILKLLIDKGVDINaknrvnyl 178
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 228 -TKGLDDD-------TPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA---NSPTMVNLLLGKG 286
Cdd:PHA03100 179 lSYGVPINikdvygfTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAilnNNKEIFKLLLNNG 248
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
160-229 |
1.80e-12 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 65.14 E-value: 1.80e-12
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNERGETRLHRAAIRGDARRIKELISEgADVNVKDFaGWTALHEACNRGYYDIAKQLLAAGAEVNTK 229
Cdd:pfam12796 23 ANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKDN-GRTALHYAARSGHLEIVKLLLEKGADINVK 90
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1857-2368 |
2.29e-12 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 73.43 E-value: 2.29e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1857 PPPDSvfSNLPPKSSPSPrgELLTPAIEG-ALPPDL-----GLPLDATEDQQATAAILPPEPSylepldegpfntvitee 1930
Cdd:PHA03247 2502 GPPDP--DAPPAPSRLAP--AILPDEPVGePVHPRMltwirGLEELASDDAGDPPPPLPPAAP----------------- 2560
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1931 pvewtHSAAEQSLPSSLIASASETPVswpVGSELmlKSPQRFAESPKHFCPGEPlhsttPGPFSAAEPTYPVSPGSYPL- 2009
Cdd:PHA03247 2561 -----PAAPDRSVPPPRPAPRPSEPA---VTSRA--RRPDAPPQSARPRAPVDD-----RGDPRGPAPPSPLPPDTHAPd 2625
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2010 ---PAPEPALEEVKDGGTGAIPVAIAAAEGAAPYTAPTRLESFFSNCKPHPDAPLDTAPEPASVTTVAQVEALG---PLE 2083
Cdd:PHA03247 2626 pppPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLAdppPPP 2705
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2084 SSFLDSSHSISALSQVEPVSWHEAFTSPEDDLDLGPFSLPELPlqAKDASDVEAETAEASPAPPVESPP-GPTGVlsggd 2162
Cdd:PHA03247 2706 PTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGP--ATPGGPARPARPPTTAGPPAPAPPaAPAAG----- 2778
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2163 vPASTTEEPPAPPPQEASPQLSTEPEPSEETKldVVLEAAAETEVLADDSAPEASISNLVPAPSPPEQQRP--------- 2233
Cdd:PHA03247 2779 -PPRRLTRPAVASLSESRESLPSPWDPADPPA--AVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPppslplggs 2855
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2234 -AGGGDEETEAEDPSAAPC-CAPDGPTTDGLAQAPNSAEAACVVAAVEGPPGNIQPEA-----------TDPEPKPTSEA 2300
Cdd:PHA03247 2856 vAPGGDVRRRPPSRSPAAKpAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAppppqpqpqppPPPQPQPPPPP 2935
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672085415 2301 PKAPKVEEVPQRMTRNRAQMLASQSKQGIPATEKDSMPAPASRAKGRAPEEEDAQAQHPRKRRFQRSG 2368
Cdd:PHA03247 2936 PPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR 3003
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
831-1555 |
1.38e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 70.94 E-value: 1.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 831 QQERWFSDLSDSSFDFKGEDSWDSVTDYRDIKSDSVAKLILETVKEDSKEKKRDNKTREKRDFRDSffrkRDRDCVDRNS 910
Cdd:PTZ00121 1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA----RKAEDARKAE 1143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 911 EKRRdhTEKQRSFPSYLSEKDKKRRESAEGGRDRRdTLEGSRERRDGRiRSEEVHR-EDLKECGCDSTFKDKSDCDFTKT 989
Cdd:PTZ00121 1144 EARK--AEDAKRVEIARKAEDARKAEEARKAEDAK-KAEAARKAEEVR-KAEELRKaEDARKAEAARKAEEERKAEEARK 1219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 990 LEPWERPHAAR--EKEKKDALEKDRKEKGRAEKYKDKSGERER------------NEKSILEKCQKDKEFEKCfKEKKDG 1055
Cdd:PTZ00121 1220 AEDAKKAEAVKkaEEAKKDAEEAKKAEEERNNEEIRKFEEARMahfarrqaaikaEEARKADELKKAEEKKKA-DEAKKA 1298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1056 KEKHKDTHSKDRKTPFDQLREKKEKAFSSLISEDFSERKDDRKGK--EKSWYIADIFTDESEDEKEECVASSFKTGEtgD 1133
Cdd:PTZ00121 1299 EEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKaaEAAKAEAEAAADEAEAAEEKAEAAEKKKEE--A 1376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1134 SQRAESLQEKEDGREHPSDRHRKASSDRQHTEKPRDKEPKEKRkdrgaAEGGKDKKEKIFEKHKEKKDKECAEKYKERKD 1213
Cdd:PTZ00121 1377 KKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKK-----ADEAKKKAEEKKKADEAKKKAEEAKKADEAKK 1451
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1214 RASvdsapEKKNKQKLPEKVEKKHfVEDKAKSKHKEKPEKDHSRERKSSRGPDVEKSLLEKLEEEALHDYRE-------D 1286
Cdd:PTZ00121 1452 KAE-----EAKKAEEAKKKAEEAK-KADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKaeeakkaD 1525
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1287 SNDKISEVSSDSFADHGQEPSLSTLLEVSFSEPPAEDKARESTCLSEKLKERERERHRHSSSSSKKSHERERAKKEKADK 1366
Cdd:PTZ00121 1526 EAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1367 KEKGEDYKDGGGGRKDASQYEKdfaDAEAFGGSYTTKADTEEDLDKAIELFSSEKKDRNDSEREPAKKLEKELKPYGSST 1446
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKK---AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKK 1682
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1447 isilKEKKKREKHREKWREEKEKHRDKHIDGFLRHHK---DEPKPAAKDKDNPPNCFKEKSREESLKLSEAKLKEKFKEN 1523
Cdd:PTZ00121 1683 ----AEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKkkaEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKK 1758
|
730 740 750
....*....|....*....|....*....|....*
gi 672085415 1524 AEREKGDSVKMSNGNDKPLPS---RDANKKDSRPR 1555
Cdd:PTZ00121 1759 IAHLKKEEEKKAEEIRKEKEAvieEELDEEDEKRR 1793
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
182-258 |
2.55e-11 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 68.54 E-value: 2.55e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672085415 182 RIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGN 258
Cdd:PHA03100 174 RVNYLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPS 250
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
179-286 |
4.36e-11 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 68.13 E-value: 4.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 179 DARRIKELISEGADVNVKDFAGWTALHEACNRG---YYDIAKQLLAAGAEVNTKGLDDDTPLHD-AANNGHYKVVKLLLR 254
Cdd:PHA03095 26 TVEEVRRLLAAGADVNFRGEYGKTPLHLYLHYSsekVKDIVRLLLEAGADVNAPERCGFTPLHLyLYNATTLDVIKLLIK 105
|
90 100 110
....*....|....*....|....*....|....*..
gi 672085415 255 YGGNPQQSNRKGETPLKV-----ANSPTMVNLLLGKG 286
Cdd:PHA03095 106 AGADVNAKDKVGRTPLHVylsgfNINPKVIRLLLRKG 142
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
693-1334 |
1.46e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.47 E-value: 1.46e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 693 RDKLSKTKSEDKEWLFKDEKALKRMKDVSKDTSRAFREERDRPSKTERERSTKEKSPKEEKLRLYKEERKKKSKDRPFKL 772
Cdd:PTZ00121 1335 KKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAA 1414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 773 EKKNDMKEVSKEKEKAFREDKEKLKKEKLCRDDAAfddycnKSQFLDHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSW 852
Cdd:PTZ00121 1415 AAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEA------KKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA 1488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 853 DSVTDYRDIKSDSVAKliletvKEDSKEKKRDNKTREKRDFRDSFFRKRDRdcvdRNSEKRRDHTEKQRSFPSYLSEKDK 932
Cdd:PTZ00121 1489 KKKAEEAKKKADEAKK------AAEAKKKADEAKKAEEAKKADEAKKAEEA----KKADEAKKAEEKKKADELKKAEELK 1558
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 933 KRRESAEGGRDRRdtlegSRERRDGRIRSEEVHREDLKecgcdstfkdksdcdftKTLEPWERPHAAREKEKKDALEKDR 1012
Cdd:PTZ00121 1559 KAEEKKKAEEAKK-----AEEDKNMALRKAEEAKKAEE-----------------ARIEEVMKLYEEEKKMKAEEAKKAE 1616
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1013 KEKGRAEKYKDKSGERERNEKSILEKCQKDKEFEKCFKEKKDGKEKHKDTHSKDrktpfdqlREKKEKAfSSLISEDFSE 1092
Cdd:PTZ00121 1617 EAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA--------EEDKKKA-EEAKKAEEDE 1687
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1093 RKDDRKGKEKSWYIADIFTDESEDEKEECVASSFKTGETGDSQRAESLQEKEDGREHPSDRHRKASSDR---QHTEKPRD 1169
Cdd:PTZ00121 1688 KKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKkkiAHLKKEEE 1767
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1170 KEPKEKRKDRGAA--EGGKDKKEKifekhkekKDKECAEKYKERKDRASVDSAPEKK-----NKQKLPEKVEKKHFVEDK 1242
Cdd:PTZ00121 1768 KKAEEIRKEKEAVieEELDEEDEK--------RRMEVDKKIKDIFDNFANIIEGGKEgnlviNDSKEMEDSAIKEVADSK 1839
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1243 AKSKHKEKPEKDHSRERKSSRGPDVEKSLLEKLEEEALHDYRE-----------DSNDKISEVSSDSFADHGQEPSLSTL 1311
Cdd:PTZ00121 1840 NMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEeieeadeiekiDKDDIEREIPNNNMAGKNNDIIDDKL 1919
|
650 660
....*....|....*....|...
gi 672085415 1312 LEVSFSEPPAEDKARESTCLSEK 1334
Cdd:PTZ00121 1920 DKDEYIKRDAEETREEIIKISKK 1942
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
119-286 |
1.70e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 66.63 E-value: 1.70e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 119 LLMQMTAEESANSPDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDF 198
Cdd:PHA02876 327 LIMLGADVNAADRLYITPLHQASTLDRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQ 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 199 AGWTALHEA-CNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAA-NNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA-NS 275
Cdd:PHA02876 407 KIGTALHFAlCGTNPYMSVKTLIDRGANVNSKNKDLSTPLHYACkKNCKLDVIEMLLDNGADVNAINIQNQYPLLIAlEY 486
|
170
....*....|.
gi 672085415 276 PTMVNLLLGKG 286
Cdd:PHA02876 487 HGIVNILLHYG 497
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1793-2342 |
6.60e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 65.34 E-value: 6.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1793 QSVPAASSFDSPVQHLLEEKAPLPPVPAEKFACLSPEYYSPDYGIPSPkvdtlhcpPTAVVSATPPPDsvfsnlPPKSSP 1872
Cdd:PHA03247 2566 RSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAP--------PSPLPPDTHAPD------PPPPSP 2631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1873 SPRGELLTPAIEGALPPD-----------LGLPLDATEDQQATAAILPPE-------------------PSYLEPLDEGP 1922
Cdd:PHA03247 2632 SPAANEPDPHPPPTVPPPerprddpapgrVSRPRRARRLGRAAQASSPPQrprrraarptvgsltsladPPPPPPTPEPA 2711
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1923 FNTVITEEPVEWTHSAAEQSLPSSLIASASETPVSWPVGSelmlKSPQRFAESPkhfcpgeplhsTTPGPFSAAEPTYPV 2002
Cdd:PHA03247 2712 PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATP----GGPARPARPP-----------TTAGPPAPAPPAAPA 2776
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2003 SPGSYPLPAPEPALEEVkdgGTGAIPVAIAAAEGAAPYTAPTRLEsffsnckPHPDAPLDTAPEPASVTTVAQVEALGPL 2082
Cdd:PHA03247 2777 AGPPRRLTRPAVASLSE---SRESLPSPWDPADPPAAVLAPAAAL-------PPAASPAGPLPPPTSAQPTAPPPPPGPP 2846
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2083 ESSfldsshsisalsqvepvswheaftspeddLDLGPFSLPELPLQAKDASDVEAETAEASPAPPVESPPGPTgvlsggd 2162
Cdd:PHA03247 2847 PPS-----------------------------LPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPA------- 2890
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2163 VPASTTEEPPAPPPQEASPQLSTEPEPSEETKLDVVLEaaaetevladdsapeasisnlvPAPSPPEQQRPAgggdeete 2242
Cdd:PHA03247 2891 VSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQ----------------------PQPPPPPPPRPQ-------- 2940
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2243 aedpsaapccAPDGPTTDGLAQAPNSAEAACVVAAVEGPPGNIQPEATDPEPKPTSEAPKAPkveevPQRMTRNRAQMLA 2322
Cdd:PHA03247 2941 ----------PPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASS-----TPPLTGHSLSRVS 3005
|
570 580
....*....|....*....|
gi 672085415 2323 SQSKQgiPATEKDSMPAPAS 2342
Cdd:PHA03247 3006 SWASS--LALHEETDPPPVS 3023
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
160-286 |
9.42e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 63.75 E-value: 9.42e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNE-RGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLH 238
Cdd:PHA02878 160 INMKDRhKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLH 239
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 672085415 239 DAANN-GHYKVVKLLLRYGGNPQ-QSNRKGETPLKVA-NSPTMVNLLLGKG 286
Cdd:PHA02878 240 ISVGYcKDYDILKLLLEHGVDVNaKSYILGLTALHSSiKSERKLKLLLEYG 290
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1637-2154 |
9.71e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 64.96 E-value: 9.71e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1637 PAP--VLPTGEGKPH-SGPGTESKDWLAGQPLKEVLPASPRTEQGRPTGVPTPTSVVSCPsyeevmHTPRTPSCSAddyp 1713
Cdd:PHA03247 2562 AAPdrSVPPPRPAPRpSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDT------HAPDPPPPSP---- 2631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1714 dlvfdctdSQHSMPVSTTSTSACSPPFFDRFSVASSVV-----------AENAGQTPTRPistnlyrsisvdirRTPEEE 1782
Cdd:PHA03247 2632 --------SPAANEPDPHPPPTVPPPERPRDDPAPGRVsrprrarrlgrAAQASSPPQRP--------------RRRAAR 2689
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1783 FSVGdklfrqqsvPAASSFDSPVQHLLEEKAPLPPVPAEKfacLSPEYYSPDYGIPSPKVDTLhCPPTAVVSATP----- 1857
Cdd:PHA03247 2690 PTVG---------SLTSLADPPPPPPTPEPAPHALVSATP---LPPGPAAARQASPALPAAPA-PPAVPAGPATPggpar 2756
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1858 PPDSVFSNLPPKSSPsPRGELLTPaiegalPPDLGLPLDATEDQQATAAILPPEPSYLEPLDEGPFNTVITEEPVEWTHS 1937
Cdd:PHA03247 2757 PARPPTTAGPPAPAP-PAAPAAGP------PRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLP 2829
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1938 AAEQSLPSSLIASASETPVSWPVGSELMLKSPQRfAESPKHFCPGEPLHSTTPGPFSAAEPTYPVSPGSYPLPAPEPALE 2017
Cdd:PHA03247 2830 PPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVR-RRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP 2908
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2018 EVKDGGTGAIPvaiAAAEGAAPYTAPTRLESFFSNCKPHPDAPLDTAPEPASVTTVAQVEALGPLE-------------- 2083
Cdd:PHA03247 2909 PQPQAPPPPQP---QPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRvavprfrvpqpaps 2985
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2084 ------SSFLDSSHSISALSQ------------VEPVSWHEAFTSPEDDLDLGPFSLPELPLQAKDASDVEAETAEasPA 2145
Cdd:PHA03247 2986 reapasSTPPLTGHSLSRVSSwasslalheetdPPPVSLKQTLWPPDDTEDSDADSLFDSDSERSDLEALDPLPPE--PH 3063
|
....*....
gi 672085415 2146 PPVESPPGP 2154
Cdd:PHA03247 3064 DPFAHEPDP 3072
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
175-255 |
1.38e-09 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 63.76 E-value: 1.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 175 AIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLR 254
Cdd:PTZ00322 90 AASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSR 169
|
.
gi 672085415 255 Y 255
Cdd:PTZ00322 170 H 170
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
200-253 |
8.36e-09 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 53.43 E-value: 8.36e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 672085415 200 GWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLL 253
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
159-273 |
1.12e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 60.28 E-value: 1.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 159 KVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGY-YDIAKQLLAAGAEVNTK----GLdd 233
Cdd:PHA02878 193 NVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVGYCKdYDILKLLLEHGVDVNAKsyilGL-- 270
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 672085415 234 dTPLHDAANNGhyKVVKLLLRYGGNPQQSNRKGETPLKVA 273
Cdd:PHA02878 271 -TALHSSIKSE--RKLKLLLEYGADINSLNSYKLTPLSSA 307
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
216-284 |
2.50e-08 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 59.53 E-value: 2.50e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672085415 216 AKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA---NSPTMVNLLLG 284
Cdd:PTZ00322 98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAeenGFREVVQLLSR 169
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
183-270 |
3.24e-08 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 58.82 E-value: 3.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 183 IKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQS 262
Cdd:PHA02874 107 IKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVK 186
|
....*...
gi 672085415 263 NRKGETPL 270
Cdd:PHA02874 187 DNNGESPL 194
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
160-273 |
1.21e-07 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 56.90 E-value: 1.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEAC--NRGyydiAKQLLAAGAEVNTKGLDDDTPL 237
Cdd:PHA02874 183 ANVKDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIihNRS----AIELLINNASINDQDIDGSTPL 258
|
90 100 110
....*....|....*....|....*....|....*..
gi 672085415 238 HDAANNGHYK-VVKLLLRYGGNPQQSNRKGETPLKVA 273
Cdd:PHA02874 259 HHAINPPCDIdIIDILLYHKADISIKDNKGENPIDTA 295
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
169-220 |
1.46e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 49.97 E-value: 1.46e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 672085415 169 TRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLL 220
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
160-259 |
6.01e-07 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 54.65 E-value: 6.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNERGETRLHRAAIRGDARR-IKELISEGADVNVKDFAGWTALHeACNRGY---YDIAKQLLAAGAEVNTKGLDDDT 235
Cdd:PHA03095 76 VNAPERCGFTPLHLYLYNATTLDvIKLLIKAGADVNAKDKVGRTPLH-VYLSGFninPKVIRLLLRKGADVNALDLYGMT 154
|
90 100
....*....|....*....|....*.
gi 672085415 236 PLHD--AANNGHYKVVKLLLRYGGNP 259
Cdd:PHA03095 155 PLAVllKSRNANVELLRLLIDAGADV 180
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
183-286 |
9.87e-07 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 53.90 E-value: 9.87e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 183 IKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHY-----KVVKLLLRYGG 257
Cdd:PHA03100 18 IKYIIMEDDLNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHYLSNIKYNltdvkEIVKLLLEYGA 97
|
90 100 110
....*....|....*....|....*....|....
gi 672085415 258 NPQQSNRKGETPLKVA-----NSPTMVNLLLGKG 286
Cdd:PHA03100 98 NVNAPDNNGITPLLYAiskksNSYSIVEYLLDNG 131
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
219-273 |
1.25e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 47.34 E-value: 1.25e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 672085415 219 LLAAG-AEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA 273
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
168-286 |
1.61e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 53.07 E-value: 1.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 168 ETRLHRAAIRGDARRIKELISEGA---DVNVKDfaGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNG 244
Cdd:PHA02875 69 ESELHDAVEEGDVKAVEELLDLGKfadDVFYKD--GMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMG 146
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672085415 245 HYKVVKLLLRY---------------------------------GGNPQQSNRKGETPLKVA----NSPTMVNLLLGKG 286
Cdd:PHA02875 147 DIKGIELLIDHkacldiedccgctpliiamakgdiaickmlldsGANIDYFGKNGCVAALCYaienNKIDIVRLFIKRG 225
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
174-286 |
1.86e-06 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 53.72 E-value: 1.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 174 AAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLHDAANNGHYKV----- 248
Cdd:PLN03192 532 VASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIfrily 611
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672085415 249 --------------------------VKLLLRYGGNPQQSNRKGETPLKVA---NSPTMVNLLLGKG 286
Cdd:PLN03192 612 hfasisdphaagdllctaakrndltaMKELLKQGLNVDSEDHQGATALQVAmaeDHVDMVRLLIMNG 678
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
158-283 |
1.96e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 53.53 E-value: 1.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 158 DKVNKRNERgeTRLHRAAIRGDARRIKE-LISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTP 236
Cdd:PHA02876 137 DKINESIEY--MKLIKERIQQDELLIAEmLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNIIALDDLSV 214
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 672085415 237 LHDAANNGHYKVVKLLLrygGNPQQSNRKGETPLK-VANSPTMVNLLL 283
Cdd:PHA02876 215 LECAVDSKNIDTIKAII---DNRSNINKNDLSLLKaIRNEDLETSLLL 259
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
1799-2188 |
2.14e-06 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 53.62 E-value: 2.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1799 SSFDSPVQHLLEEKAPL------PPVPAekfaCLSPEYYSPDYGIPSPKVDTLHCPPTAVVSATPPPDSVFSNLPPKSSP 1872
Cdd:pfam03154 156 SDSDSSAQQQILQTQPPvlqaqsGAASP----PSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTLI 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1873 SPRGELLTPAIEGALPPDLGLPLDATEDQQATAAIlpPEPSYLEPLDEGPFNtvITEEPVEWTHSAAEQSLPSSLIASAS 1952
Cdd:pfam03154 232 QQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPL--PQPSLHGQMPPMPHS--LQTGPSHMQHPVPPQPFPLTPQSSQS 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1953 ETPVSwpvgselmlksPQRFAESPKHFCPgeplhsTTPGPFSAAEPTYPvsPGSYPLPAPEPALEEVKDGGTGAIPVAIA 2032
Cdd:pfam03154 308 QVPPG-----------PSPAAPGQSQQRI------HTPPSQSQLQSQQP--PREQPLPPAPLSMPHIKPPPTTPIPQLPN 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2033 AAEGAAP--YTAPTRLeSFFSNCKPHP----------DAPLDTAPEPASVTTVAQVEALGPLESSFLDSSHSISALSQVE 2100
Cdd:pfam03154 369 PQSHKHPphLSGPSPF-QMNSNLPPPPalkplsslstHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASH 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2101 PVSWHEAFTSPEDDLDLGPFsLPELPLQAKDASDVEAETaeaSPAPPVESPPGPTGVLSGGDVPASTTEEPPAPPPQEAS 2180
Cdd:pfam03154 448 PPTSGLHQVPSQSPFPQHPF-VPGGPPPITPPSGPPTST---SSAMPGIQPPSSASVSSSGPVPAAVSCPLPPVQIKEEA 523
|
....*...
gi 672085415 2181 PQLSTEPE 2188
Cdd:pfam03154 524 LDEAEEPE 531
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
175-288 |
2.56e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 52.66 E-value: 2.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 175 AIR-GDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQL-----------------------LAAGAEVNTKG 230
Cdd:PHA02874 42 AIRsGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLidngvdtsilpipciekdmiktiLDCGIDVNIKD 121
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672085415 231 LDDDTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA---NSPTMVNLLLGKGTY 288
Cdd:PHA02874 122 AELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAikhNFFDIIKLLLEKGAY 182
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
159-237 |
3.01e-06 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 51.49 E-value: 3.01e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672085415 159 KVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPL 237
Cdd:COG0666 211 DVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
163-285 |
3.66e-06 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 52.33 E-value: 3.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 163 RNERGETRLHRAA--IRGDARRIKELISEGADVNVKDFAGWTALHEA-----CNRGYYDiakQLLAAGAEVNTKGLDDDT 235
Cdd:PHA03095 183 VDDRFRSLLHHHLqsFKPRARIVRELIRAGCDPAATDMLGNTPLHSMatgssCKRSLVL---PLLIAGISINARNRYGQT 259
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 672085415 236 PLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA---NSPTMVNLLLGK 285
Cdd:PHA03095 260 PLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMvrnNNGRAVRAALAK 312
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
981-1636 |
5.77e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.07 E-value: 5.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 981 KSDCDFTKTLEPWERPHAAREKEKKDALEKDRKEKGRAE---KYKDKSGERERNEKSILEKCQKDKEFEKCFKEKKDGKE 1057
Cdd:PTZ00121 1063 KAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEeakKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKA 1142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1058 KHKDTHSKDRKTPFDQLREKKEKAFSSLISEDFSERKDDRKGKE----KSWYIADIFTDESEDEKEECVASSFKTGETGD 1133
Cdd:PTZ00121 1143 EEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEvrkaEELRKAEDARKAEAARKAEEERKAEEARKAED 1222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1134 SQRAESLQEKEDGREHpSDRHRKASSDRQHTEKPRDKEPKEKRKDRGAAEGGKDKKEKIfEKHKEKKDKECAEKYKERKD 1213
Cdd:PTZ00121 1223 AKKAEAVKKAEEAKKD-AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-DELKKAEEKKKADEAKKAEE 1300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1214 RASVDS----APEKKNKQKLPEKVEKKHFVEDKAKSKHKEKPEKDHSRERKSSRGPDVEKSLLEKLEEEALHDYR----- 1284
Cdd:PTZ00121 1301 KKKADEakkkAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEakkka 1380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1285 EDSNDKISEVSSDSFADHGQEPSLSTLLEVSFSEpPAEDKARESTCLSEKLKERERERHRHSSSSSKKSHERERAKKEKA 1364
Cdd:PTZ00121 1381 DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAA-AAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKA 1459
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1365 DKKEKGEDYKDGGGGRKDASQYEKDFADAEAFGGSYTTKAD----TEEDLDKAIELFSSEKKDRNDSER--EPAKKLEKE 1438
Cdd:PTZ00121 1460 EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADeakkAAEAKKKADEAKKAEEAKKADEAKkaEEAKKADEA 1539
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1439 LKPYGSSTISILKEKKKREKHREKWREEKEKHRDKHIDGFLRHHKDEPKPAAKDKDNPPNCFKEKSR---EESLKLSEAK 1515
Cdd:PTZ00121 1540 KKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKmkaEEAKKAEEAK 1619
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1516 LK--EKFKENAEREKGDSVKMSNGNDK----PLPSRDANKKDSRPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKE 1589
Cdd:PTZ00121 1620 IKaeELKKAEEEKKKVEQLKKKEAEEKkkaeELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE 1699
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 672085415 1590 RMKQMEKMRHRSGDPKLK--EKKPTDDGRKKSLDFPSKKALGLDKKVKE 1636
Cdd:PTZ00121 1700 EAKKAEELKKKEAEEKKKaeELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1601-1946 |
6.66e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.25 E-value: 6.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1601 SGDPKLKEKKPTDDGRKKSLDFPSKKALGLDKKVKEPAPVLPTGEGKPhSGPGTESKDWLAGQPLKEVLPASPRTEQGRP 1680
Cdd:PHA03247 2698 LADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVP-AGPATPGGPARPARPPTTAGPPAPAPPAAPA 2776
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1681 TGVP---TPTSVVSCPSYEEVMHTPRTPSCSADDYPDLVFDCTDSQHSMPVSTTSTSAC-------SPPFFDRFSVASSV 1750
Cdd:PHA03247 2777 AGPPrrlTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQptappppPGPPPPSLPLGGSV 2856
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1751 V--AENAGQTPTRPISTNLYRSISVDIRRTPEEEFSVGDKLFRQ---------QSVPAASSFDSPVQHLLEEKAPLPPVP 1819
Cdd:PHA03247 2857 ApgGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALppdqperppQPQAPPPPQPQPQPPPPPQPQPPPPPP 2936
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1820 AEKFACLSPEYYSPDYGIPSPKVDTLH----CPPTAVVSATPPPDSVFSNLPPKSSPSPRGELLTPAI----------EG 1885
Cdd:PHA03247 2937 PRPQPPLAPTTDPAGAGEPSGAVPQPWlgalVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVsswasslalhEE 3016
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672085415 1886 ALPPDLGL-----PLDATEDQQATAAILP-PEPSYLEPLD--EGPFNTVITEEPVEWTHSAAEQSLPSS 1946
Cdd:PHA03247 3017 TDPPPVSLkqtlwPPDDTEDSDADSLFDSdSERSDLEALDplPPEPHDPFAHEPDPATPEAGARESPSS 3085
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
160-207 |
8.00e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 45.42 E-value: 8.00e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 672085415 160 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEA 207
Cdd:pfam13857 9 LNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1981-2352 |
8.29e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 51.86 E-value: 8.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1981 PGEPLHSttpgpfSAAEPTYPVSPGsyplPAPEPaleevkdgGTGAIPVAIAAAEGAAPytAPTRLesffsnckphPDAP 2060
Cdd:PHA03247 2475 PGAPVYR------RPAEARFPFAAG----AAPDP--------GGGGPPDPDAPPAPSRL--APAIL----------PDEP 2524
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2061 LDTAPEPASVTTVAQVEALG---------PLESSFLDSSHSISA-LSQVEPVSWHEAFTSPEDDLDLGPFSL-PELPLQA 2129
Cdd:PHA03247 2525 VGEPVHPRMLTWIRGLEELAsddagdpppPLPPAAPPAAPDRSVpPPRPAPRPSEPAVTSRARRPDAPPQSArPRAPVDD 2604
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2130 KDASDVEAETAEASPAPPVESPPGPTGVLSGGDVPASTTEEPPAPPPQEASPQLSTEPEPSEETKLDVVLEAAAETEVLA 2209
Cdd:PHA03247 2605 RGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPR 2684
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2210 DDSAPE--ASISNLV--PAPSPPEQQRP--------------AGGGDEETEAEDPSA-APCCAPDGPTTDGLAQAPNSAE 2270
Cdd:PHA03247 2685 RRAARPtvGSLTSLAdpPPPPPTPEPAPhalvsatplppgpaAARQASPALPAAPAPpAVPAGPATPGGPARPARPPTTA 2764
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2271 AACVVAAVEGPPGNIQPEATDPEPKPTSEA----PKAPKVEEVPQRMTRNRAQMLASQSKQGIPATEKDSMPAPASRAKG 2346
Cdd:PHA03247 2765 GPPAPAPPAAPAAGPPRRLTRPAVASLSESreslPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPG 2844
|
....*.
gi 672085415 2347 RAPEEE 2352
Cdd:PHA03247 2845 PPPPSL 2850
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
232-259 |
1.60e-05 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 43.73 E-value: 1.60e-05
10 20
....*....|....*....|....*...
gi 672085415 232 DDDTPLHDAANNGHYKVVKLLLRYGGNP 259
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADI 28
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
662-1262 |
2.03e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 50.36 E-value: 2.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 662 EYEDSKQKPDKAILLENDVSTENKLKVLKH----------DRDKLSKTKSEDKEWLFKDEKALKRMKDVSKDTSRAFREE 731
Cdd:pfam02463 202 LKEQAKKALEYYQLKEKLELEEEYLLYLDYlklneeridlLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEK 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 732 rdrpSKTERERSTKEKSPKEEKLRLYKEERKKKSKDRPFKL-EKKNDMKEVSKEKEKAFREDKEKLKKEKLcRDDAAFDd 810
Cdd:pfam02463 282 ----KLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKEsEKEKKKAEKELKKEKEEIEELEKELKELE-IKREAEE- 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 811 ycNKSQFLDHEDTKFSLSDDQQERWFSDLSDSSFDFKGEDSWDSVTDYRDIKSDSVAKLILETVKEDSKE--KKRDNKTR 888
Cdd:pfam02463 356 --EEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEekKEELEILE 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 889 EKRDFRDSffrKRDRDCVDRNSEKRRDHTEKQRSFPSYLSEKDKKRRESAEGGRDRRDTLEGSRERRDGRIRSEEVHRED 968
Cdd:pfam02463 434 EEEESIEL---KQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLK 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 969 LKECGCDSTFKDKSDCDFTKTlepwERPHAAREKEK------------KDALEKDRKEKGRAEKYKDKSGERERNEKSIL 1036
Cdd:pfam02463 511 VLLALIKDGVGGRIISAHGRL----GDLGVAVENYKvaistavivevsATADEVEERQKLVRALTELPLGARKLRLLIPK 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1037 EKCQKDKEFEK-----CFKEKKDGKEKHKDTHSKDRKTPFDQLREKKEK--------------AFSSLISEDFSERKDDR 1097
Cdd:pfam02463 587 LKLPLKSIAVLeidpiLNLAQLDKATLEADEDDKRAKVVEGILKDTELTklkesakakesglrKGVSLEEGLAEKSEVKA 666
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1098 KGKEKSWYIADIftdESEDEKEECVASSFKTGETGDSQRAESLQEKEDGREHPSDRHRKASSDRQHTEKPRDKEPKEKRK 1177
Cdd:pfam02463 667 SLSELTKELLEI---QELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQ 743
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1178 DRGAAEggkDKKEKIFEKHKEKKDKECAEKYKERKDRASVDSAPEKKNKQKLPEKVEKKHFVEDKAKSKHKEKPEKDHSR 1257
Cdd:pfam02463 744 KIDEEE---EEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEE 820
|
....*
gi 672085415 1258 ERKSS 1262
Cdd:pfam02463 821 QLLIE 825
|
|
| PHA02741 |
PHA02741 |
hypothetical protein; Provisional |
160-255 |
2.11e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 165108 [Multi-domain] Cd Length: 169 Bit Score: 47.34 E-value: 2.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNERGETRLHRAAIRGDA----RRIKELISEGADVNVKD-FAGWTALHEACNRGYYDIAKQLL-AAGAEVNTKGLDD 233
Cdd:PHA02741 53 LNATDDAGQMCIHIAAEKHEAqlaaEIIDHLIELGADINAQEmLEGDTALHLAAHRRDHDLAEWLCcQPGIDLHFCNADN 132
|
90 100
....*....|....*....|..
gi 672085415 234 DTPLHDAANNGHYKVVKLLLRY 255
Cdd:PHA02741 133 KSPFELAIDNEDVAMMQILREI 154
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
160-273 |
2.55e-05 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 49.64 E-value: 2.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNERGETRLHRAAIRGDA--RRIKELISEGADVNVKDFAGWTALHEACN--RGYYDIAKQLLAAGAEVNTKGLDDDT 235
Cdd:PHA03095 145 VNALDLYGMTPLAVLLKSRNAnvELLRLLIDAGADVYAVDDRFRSLLHHHLQsfKPRARIVRELIRAGCDPAATDMLGNT 224
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 672085415 236 PLHDAANNGHYK--VVKLLLRYGGNPQQSNRKGETPLKVA 273
Cdd:PHA03095 225 PLHSMATGSSCKrsLVLPLLIAGISINARNRYGQTPLHYA 264
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
174-234 |
3.31e-05 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 49.48 E-value: 3.31e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672085415 174 AAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDD 234
Cdd:PLN03192 629 AAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDKANTDDD 689
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
159-228 |
3.98e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 48.89 E-value: 3.98e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 159 KVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNT 228
Cdd:PHA03100 184 PINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLLLNNGPSIKT 253
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
168-257 |
7.81e-05 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 48.09 E-value: 7.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 168 ETRLHRAAIRGDARRIKELI-SEGADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAE-VNTKGLDD----DTPLHDAA 241
Cdd:cd22192 18 ESPLLLAAKENDVQAIKKLLkCPSCDLFQRGALGETALHVAALYDNLEAAVVLMEAAPElVNEPMTSDlyqgETALHIAV 97
|
90
....*....|....*.
gi 672085415 242 NNGHYKVVKLLLRYGG 257
Cdd:cd22192 98 VNQNLNLVRELIARGA 113
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
160-256 |
9.79e-05 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 47.71 E-value: 9.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 160 VNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALHEACNRGYYDIAKQLLA----AGAEVNTkgldddt 235
Cdd:PHA03095 250 INARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMVRNNNGRAVRAALAknpsAETVAAT------- 322
|
90 100
....*....|....*....|....*....
gi 672085415 236 pLHDAANNGHY--------KVVKLLLRYG 256
Cdd:PHA03095 323 -LNTASVAGGDipsdatrlCVAKVVLRGA 350
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
232-264 |
1.06e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 41.51 E-value: 1.06e-04
10 20 30
....*....|....*....|....*....|....
gi 672085415 232 DDDTPLHDAA-NNGHYKVVKLLLRYGGNPQQSNR 264
Cdd:pfam00023 1 DGNTPLHLAAgRRGNLEIVKLLLSKGADVNARDK 34
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2135-2363 |
1.28e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.67 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2135 VEAETAEASPAPPVESPPGPTGVLSGGDVPASTTEEPPAPPPQEASPQlsTEPEPSEETKLDVVLEAAAETEVLADDsap 2214
Cdd:PRK07764 584 VEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAG--AAAAPAEASAAPAPGVAAPEHHPKHVA--- 658
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2215 easisnlVPAPSPPEQQRPAGGGDEETEAEDPSAAPcCAPDGPTTDGLAQAPNSAEAACVVAAVEGPPGNIQPEATDPEP 2294
Cdd:PRK07764 659 -------VPDASDGGDGWPAKAGGAAPAAPPPAPAP-AAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASA 730
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672085415 2295 KPTSEAPKAPKVEEVPQRMTRNRAQMLASQSKQGIPATEKDSMPAPASRAKGRAPEEEDAQAQHPRKRR 2363
Cdd:PRK07764 731 PSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRR 799
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
200-227 |
1.36e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 41.12 E-value: 1.36e-04
10 20
....*....|....*....|....*....
gi 672085415 200 GWTALHEACNR-GYYDIAKQLLAAGAEVN 227
Cdd:pfam00023 2 GNTPLHLAAGRrGNLEIVKLLLSKGADVN 30
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
235-283 |
1.38e-04 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 41.88 E-value: 1.38e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 672085415 235 TPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVA---NSPTMVNLLL 283
Cdd:pfam13637 3 TALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAasnGNVEVLKLLL 54
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
918-1080 |
1.40e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 47.43 E-value: 1.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 918 EKQRSFPSYLSEKDKKRRESAEGGRDRRDTLEGSRERRDGRIRSEEVHREDLKECgcdstfkdksdcdftktlepwERPH 997
Cdd:pfam17380 410 ERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVER---------------------LRQQ 468
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 998 AAREKEKKDALEKDRKEKGRAEKYKDKSGERE--RNEKSILEKCQKDKEFEKCFKEKKDG-----------KEKHKDTHS 1064
Cdd:pfam17380 469 EEERKRKKLELEKEKRDRKRAEEQRRKILEKEleERKQAMIEEERKRKLLEKEMEERQKAiyeeerrreaeEERRKQQEM 548
|
170
....*....|....*.
gi 672085415 1065 KDRKTPFDQLREKKEK 1080
Cdd:pfam17380 549 EERRRIQEQMRKATEE 564
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
2128-2367 |
1.78e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 47.15 E-value: 1.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2128 QAKDASDVEAETAEASPAPPVESPPGPTGVLSGGDVPASTTEEPPAPPPQEASPQLSTEPEPSEE-----TKLDVVLEAA 2202
Cdd:PRK07003 373 PARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADrgddaADGDAPVPAK 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2203 AETEVLADDSAPEASISnlvPAPSPPEQQRPAGGGDEETEAEDPSAAPCCAPDGPTTDGLAQAPNSAEAACVVAAVEGPP 2282
Cdd:PRK07003 453 ANARASADSRCDERDAQ---PPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPA 529
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2283 gniqPEATDPEPKPTSEAPKAP--------------KVEEVPQRMTRNRAQMLASQSKQGIPATEKDSMPAPASRAKGRA 2348
Cdd:PRK07003 530 ----PEARPPTPAAAAPAARAGgaaaaldvlrnagmRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAAT 605
|
250
....*....|....*....
gi 672085415 2349 PEEEDAQAQHPRKRRFQRS 2367
Cdd:PRK07003 606 GDAPPNGAARAEQAAESRG 624
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
2126-2349 |
2.83e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 46.62 E-value: 2.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2126 PLQAKDASDVEAETAEASPAPPVESPPGPTG-------VLSGGDVPASTTEEPPAPPPQEASPQLSTEPEPSEE------ 2192
Cdd:PRK10263 319 PVAVAAAATTATQSWAAPVEPVTQTPPVASVdvppaqpTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQyneplq 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2193 ---TKLDVVLEAAAETEVLADDSAPEASISNLVPAPSPPEQQRPAGGGDEETEAEDPSA-APCCAPDGPTTDGLAQAPns 2268
Cdd:PRK10263 399 qpvQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFApQSTYQTEQTYQQPAAQEP-- 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2269 aeaacvvaAVEGPPGNIQPEATDPEPKPTSEAPKAPKV---EEVPQRMTRNRAQMLASQskQGIPATEKDSMPAPASRAK 2345
Cdd:PRK10263 477 --------LYQQPQPVEQQPVVEPEPVVEETKPARPPLyyfEEVEEKRAREREQLAAWY--QPIPEPVKEPEPIKSSLKA 546
|
....
gi 672085415 2346 GRAP 2349
Cdd:PRK10263 547 PSVA 550
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
1987-2259 |
2.98e-04 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 46.11 E-value: 2.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1987 STTPGPFSAAEPTYPVSPGSYPLPAPEpalEEVKDGGTGAIPVAIAAAEGAAPYTAPTRLESFFSNCKPHPDAPLDTAPE 2066
Cdd:pfam17823 120 SSSPSSAAQSLPAAIAALPSEAFSAPR---AAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPT 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2067 PASVTTVAQVEALGPLESSFLDSSHSI--SALSQVePVSWHEAFTSPEDDLDLGPFSLPELPLQAKD------------- 2131
Cdd:pfam17823 197 TAASSAPATLTPARGISTAATATGHPAagTALAAV-GNSSPAAGTVTAAVGTVTPAALATLAAAAGTvasaagtinmgdp 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2132 -------ASDVEAETAEASPAPPVESPP-GPTGVLSGgDVPASTTEEPPAPPPQEASPQLSTePEPSEETKLDVVLEAAA 2203
Cdd:pfam17823 276 harrlspAKHMPSDTMARNPAAPMGAQAqGPIIQVST-DQPVHNTAGEPTPSPSNTTLEPNT-PKSVASTNLAVVTTTKA 353
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672085415 2204 ETE--------VLADDSAPE--ASISNLVPAPSPPEQQRPAGGGDEETEAEDPSAAPCCAPDGPTT 2259
Cdd:pfam17823 354 QAKepsaspvpVLHTSMIPEveATSPTTQPSPLLPTQGAAGPGILLAPEQVATEATAGTASAGPTP 419
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
186-238 |
3.03e-04 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 40.79 E-value: 3.03e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 672085415 186 LISEG-ADVNVKDFAGWTALHEACNRGYYDIAKQLLAAGAEVNTKGLDDDTPLH 238
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALD 54
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
200-227 |
3.61e-04 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 39.88 E-value: 3.61e-04
10 20
....*....|....*....|....*...
gi 672085415 200 GWTALHEACNRGYYDIAKQLLAAGAEVN 227
Cdd:smart00248 2 GRTPLHLAAENGNLEVVKLLLDKGADIN 29
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
2054-2355 |
3.77e-04 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 45.82 E-value: 3.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2054 KPHPDAPLDTAPEPASVTTVAQVEALGPLESsfldsshsISALSQVEPVSWHEAFTSPEDDLDLGPFSLPELPLQAKDAS 2133
Cdd:COG5180 77 VAEPEAYLDPAPPKSSPDTPEEQLGAPAGDL--------LVLPAAKTPELAAGALPAPAAAAALPKAKVTREATSASAGV 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2134 DVEAetAEASPAPPVESPPGPTGVLSGGDVPASTTEEPPAPPPQEASPQLSTEPEPSEETKlDVVLEAAAETEVLADDSA 2213
Cdd:COG5180 149 ALAA--ALLQRSDPILAKDPDGDSASTLPPPAEKLDKVLTEPRDALKDSPEKLDRPKVEVK-DEAQEEPPDLTGGADHPR 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2214 PEASISNLVPAPSPPEQQRPAGGGDEETEAEDPSAAPCCAPDGPTTDGLAQAPNSAEAACVVAAVEGPPGNIQPEATDpe 2293
Cdd:COG5180 226 PEAASSPKVDPPSTSEARSRPATVDAQPEMRPPADAKERRRAAIGDTPAAEPPGLPVLEAGSEPQSDAPEAETARPID-- 303
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672085415 2294 PKPTSEAPKAPKVEEVPQRMTRNRAQM--LASQSKQGIPATEKD-----SMPAPASRAKGRAPEEEDAQ 2355
Cdd:COG5180 304 VKGVASAPPATRPVRPPGGARDPGTPRpgQPTERPAGVPEAASDagqppSAYPPAEEAVPGKPLEQGAP 372
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2152-2368 |
6.70e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 45.25 E-value: 6.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2152 PGPTGvlsGGDVPASTTEEPPAPPPQEASPQLSTEPEPSeetklDVVLEAAAETEVLADDSAPEASISNLVPAPS--PPE 2229
Cdd:PRK12323 365 PGQSG---GGAGPATAAAAPVAQPAPAAAAPAAAAPAPA-----APPAAPAAAPAAAAAARAVAAAPARRSPAPEalAAA 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2230 QQRPAGGGDEETEaedPSAAPCCAPDGPTTDGLAQAPNSAEAACVVAAVEGPPGniQPEATDPEPKPTSEAPKAPKVEEV 2309
Cdd:PRK12323 437 RQASARGPGGAPA---PAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAA--APAPADDDPPPWEELPPEFASPAP 511
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672085415 2310 PQRMTRNRAQMLASQSKQGI--PATEKDSMPAPASRAKGRAPEEEDAQAQHPRKRRFQRSG 2368
Cdd:PRK12323 512 AQPDAAPAGWVAESIPDPATadPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASG 572
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
167-270 |
7.57e-04 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 45.00 E-value: 7.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 167 GETRLHRAAIRgDARRIKELISEGADVNVKD------FAGWTALHEACNRGYYDIAKQLLAAGAEVNT---------KGL 231
Cdd:cd22192 51 GETALHVAALY-DNLEAAVVLMEAAPELVNEpmtsdlYQGETALHIAVVNQNLNLVRELIARGADVVSpratgtffrPGP 129
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 672085415 232 DD-----DTPLHDAANNGHYKVVKLLLRYGGNPQQSNRKGETPL 270
Cdd:cd22192 130 KNliyygEHPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVL 173
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2128-2343 |
7.61e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.87 E-value: 7.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2128 QAKDASDVEAETAEASPAPPVESPPGPTGVLSGGDVPASTTEEPPAPPPQEASPQLSTEPEPSEETKLDVVLEAAAETev 2207
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAP-- 448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2208 lADDSAPEASISNLVPAPSPPEQQRPAGGGDEETEAEdPSAAPCCAPDG-PTTDGLAQAPNSAEAACVVAAVEGPPGNIQ 2286
Cdd:PRK12323 449 -APAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAA-PAAAPAPADDDpPPWEELPPEFASPAPAQPDAAPAGWVAESI 526
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672085415 2287 PEATDPEPKPT----SEAPKAPKVEEVPQRMTRNRAQMLASQSKQGIPATEKDSMPAPASR 2343
Cdd:PRK12323 527 PDPATADPDDAfetlAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAAR 587
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
1850-2381 |
8.38e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 45.08 E-value: 8.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1850 TAVVSATPPPDSVfsnLPPKSSPSPRGELLTPAIE--GALPPDLGLPL--DATEDQQATAAILPPEPSYLEPLDEGPFNT 1925
Cdd:PRK10263 328 TATQSWAAPVEPV---TQTPPVASVDVPPAQPTVAwqPVPGPQTGEPViaPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQ 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1926 VITEEPVEWTHSAAEQSLPSSLIASASETPVswPVGSELMLKSPQRFAESPKHFCPGEPLHSTTPGPFSAAEPTYPVSPG 2005
Cdd:PRK10263 405 QPYYAPAAEQPAQQPYYAPAPEQPAQQPYYA--PAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQ 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2006 SYPLPA---PEPALEEVKDGGTgaiPVAIAAAEGAAPYTAPTRLESFFSNC-----KPHPDAPLDTAPEPASVTTVAQVE 2077
Cdd:PRK10263 483 PVEQQPvvePEPVVEETKPARP---PLYYFEEVEEKRAREREQLAAWYQPIpepvkEPEPIKSSLKAPSVAAVPPVEAAA 559
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2078 ALGPLESSFLD-SSHSISALSQVEPVSWHEAFTSPEDDLDLGPFslPELPLQAKDASDVEAETAEASPAPPVESPPGPTG 2156
Cdd:PRK10263 560 AVSPLASGVKKaTLATGAAATVAAPVFSLANSGGPRPQVKEGIG--PQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKA 637
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2157 VLSGGDVPASTTEEPPAPPPQEASPQLSTEPEPSEETKLDVVLEAAAETEVLADDSAPEASISNLVPAPsppEQQRPAGg 2236
Cdd:PRK10263 638 REAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQT---QQQRYSG- 713
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2237 gdeeteaEDPSAA-PCCAPD---GPTTDGLAQAPNsaeaacvvaavegppgniqpeatDPEPKPTSEAPKAPKVEEVPQR 2312
Cdd:PRK10263 714 -------EQPAGAnPFSLDDfefSPMKALLDDGPH-----------------------EPLFTPIVEPVQQPQQPVAPQQ 763
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672085415 2313 MTRNRAQMLASQSKQGIPATEKDSMPAPASRAKGRAPEEEDAQAQHPRKRRFQRSGQQLQQQLNTSTQQ 2381
Cdd:PRK10263 764 QYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQ 832
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
2132-2266 |
1.23e-03 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 44.20 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2132 ASDVEAETAEASPAPPVESPPGPTGVLSGGDVPASTTEEPPAPPPQEASPQL-STEPEPSEETKLDVVLEAAAETEVLAD 2210
Cdd:PRK13108 305 AAAVASAASAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDgESTPAVEETSEADIEREQPGDLAGQAP 384
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 672085415 2211 dSAPEASISNLVPAPSPPEQQRPAGGGDEETEAEDPSA--APCCAPDGPTTDGLAQAP 2266
Cdd:PRK13108 385 -AAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAApiPDPAKPDELAVAGPGDDP 441
|
|
| U2AF_lg |
TIGR01642 |
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ... |
875-961 |
1.36e-03 |
|
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.
Pssm-ID: 273727 [Multi-domain] Cd Length: 509 Bit Score: 44.11 E-value: 1.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 875 KEDSKEKKRDnKTREKRDFRDSFFRKRDRDCV--DRNSEKRRDHTEKQRSFpsylsEKDKKRRESAEGGRDRRDTLEGSR 952
Cdd:TIGR01642 17 RDRSSERPRR-RSRDRSRFRDRHRRSRERSYRedSRPRDRRRYDSRSPRSL-----RYSSVRRSRDRPRRRSRSVRSIEQ 90
|
....*....
gi 672085415 953 ERRDGRIRS 961
Cdd:TIGR01642 91 HRRRLRDRS 99
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1938-2363 |
1.48e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.39 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1938 AAEQSLPSsLIASASETPVSWPVGSELMLKSPQRfaespkhfcpgeplHSTTPGPFSAAEPTYPVSPGSYPLPAPepale 2017
Cdd:PHA03307 16 EGGEFFPR-PPATPGDAADDLLSGSQGQLVSDSA--------------ELAAVTVVAGAAACDRFEPPTGPPPGP----- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2018 evkdggtGAIPVAIAAAEGAAPYTAPTRLESFFSNCKPHPDAPLDTAPEPASVTTVAQVEALGPLESSFLDSSHSISALS 2097
Cdd:PHA03307 76 -------GTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2098 QVEPVSWHEAFTSPEDDldlgpfslPELPLQAKDASDVEAETAEASPAPPVESP-----------PGPTGVLSGGDVPAS 2166
Cdd:PHA03307 149 AASPPAAGASPAAVASD--------AASSRQAALPLSSPEETARAPSSPPAEPPpstppaaasprPPRRSSPISASASSP 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2167 TTEEPPAPPPQEASPQLSTEPEPSEETKLDVVLEAAAETEVLADDSAPEASISNLVPAPSPPEQQRPAGGGDEETEAEDP 2246
Cdd:PHA03307 221 APAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSP 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2247 SAAPCCAPDGPTTDGLAQAPN-SAEAACVVAAVEGPPGNIQPEATDPEPKPTSEAPKAPkvEEVPQRMTRNRAQMLASQS 2325
Cdd:PHA03307 301 SSPGSGPAPSSPRASSSSSSSrESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPP--ADPSSPRKRPRPSRAPSSP 378
|
410 420 430
....*....|....*....|....*....|....*...
gi 672085415 2326 kqgiPATEKDSMPAPASRAKGRAPEEEDAQAQHPRKRR 2363
Cdd:PHA03307 379 ----AASAGRPTRRRARAAVAGRARRRDATGRFPAGRP 412
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
654-1102 |
1.91e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.90 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 654 LKLKSFTYEYEDSKQKPDKaiLLENdvsTENKLKVLKHDRDKLSKtKSEDKEWLFKDEKALKRMKDVSKDTSRAFreERD 733
Cdd:PRK03918 296 IKLSEFYEEYLDELREIEK--RLSR---LEEEINGIEERIKELEE-KEERLEELKKKLKELEKRLEELEERHELY--EEA 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 734 RPSKTERERSTKEKSPK-----EEKLRLYKEERKKKSKDRPFKLEKKNDMKEVSKEKEKAFREDKEKLKKEKLCRDDaaf 808
Cdd:PRK03918 368 KAKKEELERLKKRLTGLtpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRE--- 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 809 ddycnksqfLDHEDTKfslsdDQQERWFSDLSDSSFDFKGEDSwdsvtDYRDIKSDSVAkliLETVKEDSKEKKRDNKTR 888
Cdd:PRK03918 445 ---------LTEEHRK-----ELLEEYTAELKRIEKELKEIEE-----KERKLRKELRE---LEKVLKKESELIKLKELA 502
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 889 EKRDFRDSFFRKRDRDCVDRNSEKRRDHTEKQRSFPSYLSEKdKKRRESAEGGRDRRDTLEgsRERRDGRIRSEEVHREd 968
Cdd:PRK03918 503 EQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSL-KKELEKLEELKKKLAELE--KKLDELEEELAELLKE- 578
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 969 LKECGcdstFKDKSDCDFT-KTLEPWER--------PHAAREKEKKDALEKDRKEKGRAE-KYKDKSGERERNEKSILEK 1038
Cdd:PRK03918 579 LEELG----FESVEELEERlKELEPFYNeylelkdaEKELEREEKELKKLEEELDKAFEElAETEKRLEELRKELEELEK 654
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672085415 1039 CQKDKEFEKCFKEKKDGKEKHKDTHSKdrktpFDQLREKKEKAFSSLisEDFSERKDDRKGKEK 1102
Cdd:PRK03918 655 KYSEEEYEELREEYLELSRELAGLRAE-----LEELEKRREEIKKTL--EKLKEELEEREKAKK 711
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1891-2357 |
2.08e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.77 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1891 LGLPLDATedqQATAAILPPEPSYLEPLDE-GPFNTVITEEPVewthsaaeqslpssliASASETPVSWPVGSELmlkSP 1969
Cdd:PHA03247 2460 LGAPFSLS---LLLGELFPGAPVYRRPAEArFPFAAGAAPDPG----------------GGGPPDPDAPPAPSRL---AP 2517
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1970 QRFAESPkhfcPGEPLH-----------------STTPGPFSAAEPTYPVSPGSYPLPAPEPALEEVKDGGTGAIPvaIA 2032
Cdd:PHA03247 2518 AILPDEP----VGEPVHprmltwirgleelasddAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRP--DA 2591
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2033 AAEGAAPYTAPTRLESFFSNCKPHPDAPLDTAPEPASVTTVAQVEALGPLESSFLDSSHSISALSQVEPVSWHEAFTSPE 2112
Cdd:PHA03247 2592 PPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLG 2671
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2113 DDLdlGPFSLPELPLQAKDASDVEAETAEASPAPPvESPPGPtgvlsggdvpastteeppapPPQEASPQLSTEPEP--- 2189
Cdd:PHA03247 2672 RAA--QASSPPQRPRRRAARPTVGSLTSLADPPPP-PPTPEP--------------------APHALVSATPLPPGPaaa 2728
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2190 ---SEETKLDVVLEAAAETEVL----------ADDSAPEASISNLVPA----------------------PSPPEQQRPA 2234
Cdd:PHA03247 2729 rqaSPALPAAPAPPAVPAGPATpggparparpPTTAGPPAPAPPAAPAagpprrltrpavaslsesreslPSPWDPADPP 2808
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2235 GGGDEETEAEDPSAAPcCAPDGPTTDGLAQAPNSAEAACVVAAVEG----PPGNIQPEATDPEPKPTSEAPKAPKVEEVP 2310
Cdd:PHA03247 2809 AAVLAPAAALPPAASP-AGPLPPPTSAQPTAPPPPPGPPPPSLPLGgsvaPGGDVRRRPPSRSPAAKPAAPARPPVRRLA 2887
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 672085415 2311 qrmtrnRAQMLASQSKQGIPATEKDSMPAPASRAKGRAPEEEDAQAQ 2357
Cdd:PHA03247 2888 ------RPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQ 2928
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
1909-2332 |
2.47e-03 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 43.51 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1909 PPEPSYLEPldegpfntvitEEPVEWTHSAAEQSLPSSLIASASETPVSWPVgselmlkspQRFAESPKHfcpgePLHST 1988
Cdd:PHA03379 408 ASEPTYGTP-----------RPPVEKPRPEVPQSLETATSHGSAQVPEPPPV---------HDLEPGPLH-----DQHSM 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1989 TPGPFSAAEPT--YPVSPGSYpLPAPepaleeVKDGGTGAIPVAIAAAEGAAPY-TAPTRLesffSNCKPHPDAPLDTAP 2065
Cdd:PHA03379 463 APCPVAQLPPGplQDLEPGDQ-LPGV------VQDGRPACAPVPAPAGPIVRPWeASLSQV----PGVAFAPVMPQPMPV 531
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2066 EPASVTTVAQVEALGPLESSFL-----DSSHSISALSQVEPVSWheaftSPEDDLDLGPFSLPELP------LQAKDASd 2134
Cdd:PHA03379 532 EPVPVPTVALERPVCPAPPLIAmqgpgETSGIVRVRERWRPAPW-----TPNPPRSPSQMSVRDRLarlraeAQPYQAS- 605
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2135 VEAETAE---ASPAPPVESPPGP-------------TGVLSGGDVPAS-------TTEEPPAPPPQEASPQLSTEPEP-- 2189
Cdd:PHA03379 606 VEVQPPQltqVSPQQPMEYPLEPeqqmfpgspfsqvADVMRAGGVPAMqpqyfdlPLQQPISQGAPLAPLRASMGPVPpv 685
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2190 --SEETKLDVVLEAAAETEVLADDSAPEAsisnlvPAPSPPEQQRPAGGGDEETEAEDPSAAPCCAPDGPTTDGLAQ-AP 2266
Cdd:PHA03379 686 paTQPQYFDIPLTEPINQGASAAHFLPQQ------PMEGPLVPERWMFQGATLSQSVRPGVAQSQYFDLPLTQPINHgAP 759
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672085415 2267 nsaeaacvvaAVEGPPGNIQPEATDPEPKPTSEAPKAPKVEEVPQRMTRNRaQMLASQSKQGIPAT 2332
Cdd:PHA03379 760 ----------AAHFLHQPPMEGPWVPEQWMFQGAPPSQGTDVVQHQLDALG-YVLHVLNHPGVPVS 814
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
2221-2351 |
2.72e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 43.13 E-value: 2.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2221 LVPAPSPPEQQRPAGGGDEETEAED-PSAAPCCAPDGPTTDglAQAPNSAEAACVVAAVEGPPGNIQPEATdPEPK-PTS 2298
Cdd:PRK14959 361 MLPRLMPVESLRPSGGGASAPSGSAaEGPASGGAATIPTPG--TQGPQGTAPAAGMTPSSAAPATPAPSAA-PSPRvPWD 437
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 672085415 2299 EAPKAPKVEEVPqrmTRNRAQMLASQSKQGIPATEKDSMPAPASRAKGRAPEE 2351
Cdd:PRK14959 438 DAPPAPPRSGIP---PRPAPRMPEASPVPGAPDSVASASDAPPTLGDPSDTAE 487
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
920-1251 |
3.55e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.03 E-value: 3.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 920 QRSFPSYLSEKDKKRRESAEG-------------GRDRRDTLEGSRERRDGRIRSEEVHREDLKECGCDS-TFKDKSDCD 985
Cdd:TIGR00618 151 QGEFAQFLKAKSKEKKELLMNlfpldqytqlalmEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERkQVLEKELKH 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 986 FTKTLEPWERPHAAREKEKKDALEKDRKEkgRAEKYKDKSGERERNEKSILEKCQKDKEFeKCFKEKKDGKEKHKDTHSK 1065
Cdd:TIGR00618 231 LREALQQTQQSHAYLTQKREAQEEQLKKQ--QLLKQLRARIEELRAQEAVLEETQERINR-ARKAAPLAAHIKAVTQIEQ 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1066 DRKTPFDQLREKKEKaFSSLISEDFSERKDDRKGKEKSWYIADIFTDESEDEKEECVASSFK---TGETGDSQRAESLQE 1142
Cdd:TIGR00618 308 QAQRIHTELQSKMRS-RAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIReisCQQHTLTQHIHTLQQ 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1143 KedgREHPSDRHRKASS------DRQHTEKPRDKEPKEKRKDRGAAEGG-KDKKEKIFEKHKEKKDKECAEKYKERKDRA 1215
Cdd:TIGR00618 387 Q---KTTLTQKLQSLCKeldilqREQATIDTRTSAFRDLQGQLAHAKKQqELQQRYAELCAAAITCTAQCEKLEKIHLQE 463
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 672085415 1216 SVDSAPEK----KNKQKLPEKVEKKHFVEDKAKSKHKEKP 1251
Cdd:TIGR00618 464 SAQSLKEReqqlQTKEQIHLQETRKKAVVLARLLELQEEP 503
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
200-228 |
4.14e-03 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 36.85 E-value: 4.14e-03
10 20
....*....|....*....|....*....
gi 672085415 200 GWTALHEACNRGYYDIAKQLLAAGAEVNT 228
Cdd:pfam13606 2 GNTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1832-2167 |
4.27e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 42.85 E-value: 4.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1832 SPDYGIPSPKVDTLHCPPTAVVSATPPPDSVF--SNLPPKSSP--SPRGELLTPAIEGALPPDLGLPLDATEDQQATAAI 1907
Cdd:PHA03307 34 DLLSGSQGQLVSDSAELAAVTVVAGAAACDRFepPTGPPPGPGteAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSS 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1908 LPPEPSYLEPLDEGPFNTVITEEPVEWTHSAAEQSLPSSLIASASETPVSWPVGSELMLKSPQRFAESPKHfCPGEPLHS 1987
Cdd:PHA03307 114 PDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETAR-APSSPPAE 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 1988 ---TTPGPFSAAEPTYPVSPGSYPLPAPEPALEEVKDGGTGAIPVAIAAAEGAAPYTAPTrlesffsNCKPHPDAPLDTA 2064
Cdd:PHA03307 193 pppSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPE-------NECPLPRPAPITL 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2065 PEPASVTTVAQVEALGPLESSfldSSHSISALSqvepvswheafTSPEDDLDLGPFSLPELPLQAKDASDVEAETAEASP 2144
Cdd:PHA03307 266 PTRIWEASGWNGPSSRPGPAS---SSSSPRERS-----------PSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSS 331
|
330 340
....*....|....*....|...
gi 672085415 2145 APPVESPPGPTGVLSGGDVPAST 2167
Cdd:PHA03307 332 SSESSRGAAVSPGPSPSRSPSPS 354
|
|
| U2AF_lg |
TIGR01642 |
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of ... |
879-970 |
6.12e-03 |
|
U2 snRNP auxilliary factor, large subunit, splicing factor; These splicing factors consist of an N-terminal arginine-rich low complexity domain followed by three tandem RNA recognition motifs (pfam00076). The well-characterized members of this family are auxilliary components of the U2 small nuclear ribonuclearprotein splicing factor (U2AF). These proteins are closely related to the CC1-like subfamily of splicing factors (TIGR01622). Members of this subfamily are found in plants, metazoa and fungi.
Pssm-ID: 273727 [Multi-domain] Cd Length: 509 Bit Score: 41.80 E-value: 6.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 879 KEKKRDNKTREKRDFRDSFFRKRDRDcVDRNSEKRRDHTEKQRSFPSYLSEKDKKRRESAEGGRDRRDTLEGSRERRDGR 958
Cdd:TIGR01642 3 EEPDREREKSRGRDRDRSSERPRRRS-RDRSRFRDRHRRSRERSYREDSRPRDRRRYDSRSPRSLRYSSVRRSRDRPRRR 81
|
90
....*....|....*
gi 672085415 959 ---IRSEEVHREDLK 970
Cdd:TIGR01642 82 srsVRSIEQHRRRLR 96
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2119-2325 |
6.67e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 41.79 E-value: 6.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2119 PFSLPELPLQAKDASDVEAETAEASPAPPVESPPGPTGVLSGGDVPASTTEEPPAPPPQEASPQLSTEPEPSEETKLDVV 2198
Cdd:PRK12323 403 PAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPAR 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672085415 2199 LEAAAETEVLADDSAPEASISNLVPAPSpPEQQRPAGGGDEETEAEDPSAAPCCAPDGPTTDGLAQAPNSAEAACVVAAV 2278
Cdd:PRK12323 483 AAPAAAPAPADDDPPPWEELPPEFASPA-PAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVV 561
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 672085415 2279 EGPPgniqPEATDPEPKPTSEAPKAPKVEEVPqrmTRNRAQMLASQS 2325
Cdd:PRK12323 562 APRP----PRASASGLPDMFDGDWPALAARLP---VRGLAQQLARQS 601
|
|
| |
