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Conserved domains on  [gi|672081159|ref|XP_008769721|]
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methylglutaconyl-CoA hydratase, mitochondrial isoform X2 [Rattus norvegicus]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 2-230 9.65e-85

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PLN02600:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 251  Bit Score: 252.03  E-value: 9.65e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:PLN02600  27 LRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSLEALSIPTIAVVEGAALGGGLEL 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  82 ALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLeqnQEGDaAYRK 161
Cdd:PLN02600 107 ALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGAREAASMGLVNYCV---PAGE-AYEK 182

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 162 ALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PLN02600 183 ALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEKRKPVYTGK 251
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
 2-230 9.65e-85

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 252.03  E-value: 9.65e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:PLN02600  27 LRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSLEALSIPTIAVVEGAALGGGLEL 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  82 ALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLeqnQEGDaAYRK 161
Cdd:PLN02600 107 ALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGAREAASMGLVNYCV---PAGE-AYEK 182

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 162 ALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PLN02600 183 ALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEKRKPVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 2-224 2.25e-58

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 184.60  E-value: 2.25e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKE-RAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLE 80
Cdd:COG1024   31 LAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKElAAAADPEEARAFARGLQRLFRALRRLPKPVIAAVNGAALGGGLE 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  81 LALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnqegDAAYR 160
Cdd:COG1024  110 LALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAEEALELGLVNRVVPD----DELLA 185

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672081159 161 KALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRP 224
Cdd:COG1024  186 AALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFLEKRK 249
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 2-229 5.28e-43

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 145.58  E-value: 5.28e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159    2 LSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:pfam00378  28 LIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTLLYTCPKPVIAAVNGYAIGGGCEL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   82 ALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQegdaAYRK 161
Cdd:pfam00378 107 ALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEALKWGLVDKVVPEDQ----LLDE 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159  162 ALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:pfam00378 183 ARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFLEKRKPPWED 250
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 2-168 8.21e-42

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 140.77  E-value: 8.21e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKM--HSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGL 79
Cdd:cd06558   31 LAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAALsdAGEEARAFIRELQELLRALLRLPKPVIAAVNGAALGGGL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  80 ELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnqegDAAY 159
Cdd:cd06558  110 ELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRISAEEALELGLVDEVVPD----EELL 185


                 ....*....
gi 672081159 160 RKALDLARE 168
Cdd:cd06558  186 AAALELARR 194
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 2-208 2.56e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 71.41  E-value: 2.56e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159    2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVIND-IANLPVPTIAAIDGLALGGGLE 80
Cdd:TIGR02441  46 FKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEGQEMFErIEKSQKPIVAAISGSCLGGGLE 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   81 LALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGdaa 158
Cdd:TIGR02441 126 LALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIRADRAKKMGIVDQLVDPLGPG--- 202

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 672081159  159 YRKALDLAREFLPQgpVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIS 208
Cdd:TIGR02441 203 LKPAEENTIEYLEE--VAVKFAQGLANGKLSINRDKGLVHKITQYVMTNP 250
 
Name Accession Description Interval E-value
PLN02600 PLN02600
enoyl-CoA hydratase
 2-230 9.65e-85

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 252.03  E-value: 9.65e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:PLN02600  27 LRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSLEALSIPTIAVVEGAALGGGLEL 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  82 ALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLeqnQEGDaAYRK 161
Cdd:PLN02600 107 ALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGAREAASMGLVNYCV---PAGE-AYEK 182

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 162 ALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PLN02600 183 ALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEKRKPVYTGK 251
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 2-230 1.48e-81

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 244.26  E-value: 1.48e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:PRK07657  36 LQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSLIRTTMEMVEQLPQPVIAAINGIALGGGLEL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  82 ALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDaayrK 161
Cdd:PRK07657 116 ALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEIGLVEFVVPAHLLEE----K 191

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 162 ALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK07657 192 AIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTKDRLEGLQAFKEKRKPMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 2-224 2.25e-58

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 184.60  E-value: 2.25e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKE-RAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLE 80
Cdd:COG1024   31 LAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKElAAAADPEEARAFARGLQRLFRALRRLPKPVIAAVNGAALGGGLE 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  81 LALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnqegDAAYR 160
Cdd:COG1024  110 LALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAEEALELGLVNRVVPD----DELLA 185

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672081159 161 KALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRP 224
Cdd:COG1024  186 AALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFLEKRK 249
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
2-229 4.13e-48

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 158.76  E-value: 4.13e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:PRK05809  36 LDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGRKFGLLGNKVFRKLENLDKPVIAAINGFALGGGCEL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  82 ALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAYRk 161
Cdd:PRK05809 116 SMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMINAEEALRIGLVNKVVEPEKLMEEAKA- 194

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159 162 aldLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK05809 195 ---LANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTEGMTAFVEKREKNFKN 259
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 2-229 5.28e-43

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 145.58  E-value: 5.28e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159    2 LSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:pfam00378  28 LIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTLLYTCPKPVIAAVNGYAIGGGCEL 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   82 ALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQegdaAYRK 161
Cdd:pfam00378 107 ALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEALKWGLVDKVVPEDQ----LLDE 182

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159  162 ALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:pfam00378 183 ARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFLEKRKPPWED 250
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 2-229 3.72e-42

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 143.47  E-value: 3.72e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLKERAKmHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:PRK06688  37 LADALEAAATDPAVRVVVLTG-AGRAFSAGGDIKDFPK-APPKPPDELAPVNRFLRAIAALPKPVVAAVNGPAVGVGVSL 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  82 ALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNqEGDAayrK 161
Cdd:PRK06688 115 ALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSAEEALRIGLVNRVVPAA-ELDA---E 190

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 162 ALDLAREfLPQGP-VAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK06688 191 ADAQAAK-LAAGPaSALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATAFIEKRKPDFTG 258
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 2-168 8.21e-42

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 140.77  E-value: 8.21e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKM--HSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGL 79
Cdd:cd06558   31 LAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAALsdAGEEARAFIRELQELLRALLRLPKPVIAAVNGAALGGGL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  80 ELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnqegDAAY 159
Cdd:cd06558  110 ELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRISAEEALELGLVDEVVPD----EELL 185


                 ....*....
gi 672081159 160 RKALDLARE 168
Cdd:cd06558  186 AAALELARR 194
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 2-229 9.03e-41

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 139.90  E-value: 9.03e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKmhssevgpfvSKIRAVIND--------IANLPVPTIAAIDGL 73
Cdd:PRK09674  34 LVNELEAAATDTSIGVCVITGN-ARFFAAGADLNEMAE----------KDLAATLNDprpqlwqrLQAFNKPLIAAVNGY 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  74 ALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnq 153
Cdd:PRK09674 103 ALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESITAQQAQQAGLVSEVFPP-- 180

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672081159 154 egDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK09674 181 --ELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHEGISAFLEKRTPDFKG 254
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 2-230 1.38e-40

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 139.38  E-value: 1.38e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEvpG-IFCAGADLKE-RAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGL 79
Cdd:PRK07658  33 LSELLDQVEKDDNVRVVVIHGE--GrFFSAGADIKEfTSVTEAEQATELAQLGQVTFERVEKFSKPVIAAIHGAALGGGL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  80 ELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQegdaAY 159
Cdd:PRK07658 111 ELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPITGAEALKWGLVNGVFPEET----LL 186

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672081159 160 RKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK07658 187 DDAKKLAKKIAGKSPATTRAVLELLQTTKSSSYYEGVKREAKIFGEVFTSEDAKEGVQAFLEKRKPSFSGK 257
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 2-230 5.23e-36

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 127.86  E-value: 5.23e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMHSSEVgpFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:PRK08138  40 LAEHFTELSEDPDIRAIVLTGG-EKVFAAGADIKEFATAGAIEM--YLRHTERYWEAIAQCPKPVIAAVNGYALGGGCEL 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  82 ALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQegdaAYRK 161
Cdd:PRK08138 117 AMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMALTGCMVPAPEALAIGLVSEVVEDEQ----TLPR 192

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 162 ALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK08138 193 ALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDSEDQKEGMDAFLEKRKPAYKGK 261
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 2-228 1.67e-35

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 126.31  E-value: 1.67e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIR-SEvpGIFCAGADLKERAKMHSSEVgpFVSKIRAVINDIANLPVPTIAAIDGLALGGGLE 80
Cdd:PRK05862  36 LGAALAAFDADEGIGAIVITgSE--KAFAAGADIKEMADLSFMDV--YKGDYITNWEKVARIRKPVIAAVAGYALGGGCE 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  81 LALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAYR 160
Cdd:PRK05862 112 LAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERAGLVSRVVPADKLLDEALA 191

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159 161 KALDLAREFLPqgpvAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYK 228
Cdd:PRK05862 192 AATTIASFSLP----AVMMAKEAVNRAYETTLAEGLLFERRLFHSLFATEDQKEGMAAFVEKRKPVFK 255
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
2-230 2.55e-35

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 125.85  E-value: 2.55e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKE-RAKMHSSEVGPFVSK------IRAVINDIANLPVPTIAAIDGLA 74
Cdd:PRK09245  36 LVAACAAINADRSVRAVILTGAGT-AFSSGGNVKDmRARVGAFGGSPADIRqgyrhgIQRIPLALYNLEVPVIAAVNGPA 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  75 LGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQE 154
Cdd:PRK09245 115 IGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEMAFTGDAIDAATALEWGLVSRVVPADQL 194

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159 155 GDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEAcyAQTIS--TKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK09245 195 LPA----ARALAERIAANPPHALRLTKRLLREGQHASLDTLLELSAA--YQALAhhTADHREAVDAFLEKRPPVFTGR 266
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
1-230 2.23e-32

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 118.28  E-value: 2.23e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   1 MLSKAVDA---LKSDKKVRTIIIrSEVPGIFCAGADLKERAKMHSSEV---GPF-VSKIRAVINDiANLPVPTIAAIDGL 73
Cdd:PRK07799  33 MLRIMVDAwdrVDNDPDIRSCIL-TGAGGAFCAGMDLKAATKKPPGDSfkdGSYdPSRIDALLKG-RRLTKPLIAAVEGP 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  74 ALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQ 153
Cdd:PRK07799 111 AIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEAKEIGLIGHVVPDGQ 190

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672081159 154 egdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK07799 191 ----ALDKALELAELINANGPLAVQAILRTIRETEGMHENEAFKIDTKIGIPVFLSEDAKEGPRAFAEKRAPNFQGR 263
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 2-228 1.49e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 113.48  E-value: 1.49e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKErakmhssevgpFVSKIRAVINDIA-----------NLPVPTIAAI 70
Cdd:PRK09076  34 LKQLVLELNADKDVYALVITGDGEKFFSAGADLNL-----------FADGDKAVAREMArrfgeafealsAFRGVSIAAI 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  71 DGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLE 150
Cdd:PRK09076 103 NGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAATALRIGLVEEVVE 182

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159 151 QNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYK 228
Cdd:PRK09076 183 KGEAREA----ALALAQKVANQSPSAVAACKTLIQAARNGPRAAALALERELFVDLFDTEDQREGVNAFLEKRAPQWK 256
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 2-229 9.01e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 111.29  E-value: 9.01e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGP--FVSkiravINDIANLPVPTIAAIDGLALGGGL 79
Cdd:PRK06494  36 LEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQAAGGKRGWPEsgFGG-----LTSRFDLDKPIIAAVNGVAMGGGF 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  80 ELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnQEGDAAy 159
Cdd:PRK06494 111 ELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTAREGLELGFVNEVVPA-GELLAA- 188

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159 160 rkALDLAREFLPQGPVAMRVAKLAINQGMEVDLvtglaiEEACYAQT--------ISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK06494 189 --AERWADDILACSPLSIRASKQAVYRGLEVSL------EEAITAQRdypavearRASQDYIEGPKAFAEKRPPRWKG 258
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
2-228 1.23e-29

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 111.13  E-value: 1.23e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMHSSEVGpfvsKIRAVINDIAN-----------LPVPTIAAI 70
Cdd:PRK07509  35 LIATIKRLKKDRGIRAVILSGE-GGAFCAGLDVKSVASSPGNAVK----LLFKRLPGNANlaqrvslgwrrLPVPVIAAL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  71 DGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLE 150
Cdd:PRK07509 110 EGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVARELTYTARVFSAEEALELGLVTHVSD 189

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 151 QnqegdaAYRKALDLAREFLPQGPVAMRVAKLAINQgMEVDLVTGLAIEEACY-AQTISTKDRLEGLLAFKEKRPPRYK 228
Cdd:PRK07509 190 D------PLAAALALAREIAQRSPDAIAAAKRLINR-SWTASVRALLARESVEqIRLLLGKNQKIAVKAQMKKRAPKFL 261
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 2-229 9.78e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 109.02  E-value: 9.78e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSE--VGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGL 79
Cdd:PRK06127  43 LPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESRSDAeaVAAYEQAVEAAQAALADYAKPTIACIRGYCIGGGM 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  80 ELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEqNQEGDAAy 159
Cdd:PRK06127 123 GIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFDAAEALRIGLVHRVTA-ADDLETA- 200

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672081159 160 rkALDLAREFLPQGPVAMRVAKLAINQ----GMEVDLVTGLAIEEACYAqtisTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK06127 201 --LADYAATIAGNAPLTLRAAKRAIAEllkdEPERDMAACQALVAACFD----SEDYREGRAAFMEKRKPVFKG 268
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
2-227 4.98e-26

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 101.37  E-value: 4.98e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAkmHSSEVGP------FVSKIRAVINDIANLPVPTIAAIDGLAL 75
Cdd:PRK05980  35 LLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFS--ASVAAGAdvalrdFVRRGQAMTARLEAFPKPVIAAVNGLAF 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  76 GGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnqeg 155
Cdd:PRK05980 113 GGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKRALELLLTGDAFSAERALEIGLVNAVVPH---- 188

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672081159 156 DAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRY 227
Cdd:PRK05980 189 EELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQFARMAGSADLREGLAAWIERRRPAY 260
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
2-158 6.33e-26

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 105.33  E-value: 6.33e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKERA---KMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGG 78
Cdd:PRK11730  39 LGEALDALEAQSDLKGLLLTSAKD-AFIVGADITEFLslfAAPEEELSQWLHFANSIFNRLEDLPVPTVAAINGYALGGG 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  79 LELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAA 158
Cdd:PRK11730 118 CECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKDVRAEDALKVGAVDAVVAPEKLQEAA 197
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
2-230 1.21e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 100.45  E-value: 1.21e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIrSEVPGIFCAGADLKERAKmhssevGPFVSKIRAVINDIANLPV--PTIAAIDGLALGGGL 79
Cdd:PRK08252  35 LAAALDELDADPDLSVGIL-TGAGGTFCAGMDLKAFAR------GERPSIPGRGFGGLTERPPrkPLIAAVEGYALAGGF 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  80 ELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAay 159
Cdd:PRK08252 108 ELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLTAERAHELGLVNRLTEPGQALDA-- 185

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672081159 160 rkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK08252 186 --ALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPVFTSADAKEGATAFAEKRAPVWTGK 254
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 2-229 2.32e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 99.68  E-value: 2.32e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVG-PFVSKIRAVINDIANLPVPTIAAIDGLALGGGLE 80
Cdd:PRK06144  40 LAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAEDAvAYERRIDRVLGALEQLRVPTIAAIAGACVGGGAA 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  81 LALACDIRVAASSAKMG----------LVETKLAiipggggtqRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLE 150
Cdd:PRK06144 120 IAAACDLRIATPSARFGfpiartlgncLSMSNLA---------RLVALLGAARVKDMLFTARLLEAEEALAAGLVNEVVE 190

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 151 QnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYaqtiSTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK06144 191 D----AALDARADALAELLAAHAPLTLRATKEALRRLRREGLPDGDDLIRMCY----MSEDFREGVEAFLEKRPPKWKG 261
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 5-229 1.24e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 98.24  E-value: 1.24e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   5 AVDALKSDKKVRTIIIRSEVPGiFCAGADLKE------RAKMHSSEVGPFVSKIRAVIND----IANLPVPTIAAIDGLA 74
Cdd:PRK06210  41 AMDRAEADPAVRVIVLTGAGRG-FCAGADMGElqtidpSDGRRDTDVRPFVGNRRPDYQTryhfLTALRKPVIAAINGAC 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  75 LGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQE 154
Cdd:PRK06210 120 AGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANALDLLLSARTFYAEEALRLGLVNRVVPPDEL 199

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672081159 155 GDAAYRKALDLAREFlpqGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK06210 200 MERTLAYAEDLARNV---SPASMAVIKRQLYEDAFQTLAEATARANREMHESLQRPDFIEGVASFLEKRPPRFPG 271
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 2-230 1.44e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 97.69  E-value: 1.44e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKMHS---SEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGG 78
Cdd:PRK05995  36 LTAAFRALDADDSVRAVVLAGAGKA-FCAGADLNWMKKMAGysdDENRADARRLADMLRAIYRCPKPVIARVHGDAYAGG 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  79 LELALACDIRVAASSAKMGLVETKLAIIPggggTQRLP---RAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnQEG 155
Cdd:PRK05995 115 MGLVAACDIAVAADHAVFCLSEVRLGLIP----ATISPyviRAMGERAARRYFLTAERFDAAEALRLGLVHEVVPA-EAL 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159 156 DAayrKALDLAREFLPQGPVAMRVAKLAINQgmevdlVTGLAIEEACYAQTIS-------TKDRLEGLLAFKEKRPPRYK 228
Cdd:PRK05995 190 DA---KVDELLAALVANSPQAVRAGKRLVRD------VAGRPIDAALIADTASrialiraTEEAREGVAAFLEKRKPAWR 260


                 ..
gi 672081159 229 GE 230
Cdd:PRK05995 261 GR 262
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 2-229 5.46e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 97.00  E-value: 5.46e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIirseVPG---IFCAGADLKERAK-------------MHSSEVGPFVSKIR----AVINDIAN 61
Cdd:PRK08260  36 LIEAFDAADADDAVRAVI----VTGagrAFCAGADLSAGGNtfdldaprtpveaDEEDRADPSDDGVRdgggRVTLRIFD 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  62 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKA 141
Cdd:PRK08260 112 SLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLVGLQTALEWVYSGRVFDAQEALD 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159 142 VGLISHVLEQNQEGDAAYrkalDLAREFLPQ-GPVAMRVAK------LAINQGMEVDLVTGLAIeeacYAQTIStKDRLE 214
Cdd:PRK08260 192 GGLVRSVHPPDELLPAAR----ALAREIADNtSPVSVALTRqmmwrmAGADHPMEAHRVDSRAI----YSRGRS-GDGKE 262

                        250
                 ....*....|....*
gi 672081159 215 GLLAFKEKRPPRYKG 229
Cdd:PRK08260 263 GVSSFLEKRPAVFPG 277
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 5-229 6.23e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 95.83  E-value: 6.23e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   5 AVDALKSDKKVRTIIIRSEvPGIFCAGADLK---ERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:PRK07511  38 ALNTAERDPSIRAVVLTGA-GGFFCAGGNLNrllENRAKPPSVQAASIDGLHDWIRAIRAFPKPVIAAVEGAAAGAGFSL 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  82 ALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAayrk 161
Cdd:PRK07511 117 ALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGKPISAERLHALGVVNRLAEPGQALAE---- 192

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159 162 ALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK07511 193 ALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFVASLHHADALEGIAAFLEKRAPDYKR 260
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
8-230 3.56e-23

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 93.99  E-value: 3.56e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   8 ALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSE----VGPFvskirAVINDIANLPVPTIAAIDGLALGGGLELAL 83
Cdd:PRK03580  40 NFRDDPELRVAIITGAGEKFFSAGWDLKAAAEGEAPDadfgPGGF-----AGLTEIFDLDKPVIAAVNGYAFGGGFELAL 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  84 ACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAYrkal 163
Cdd:PRK03580 115 AADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAEEALRWGIVNRVVPQAELMDRAR---- 190

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672081159 164 DLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAI----EEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK03580 191 ELAQQLVNSAPLAIAALKEIYRETSEMPVEEAYRYirsgVLKHYPSVLHSEDALEGPRAFAEKRDPVWKGR 261
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 5-230 9.60e-23

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 92.78  E-value: 9.60e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   5 AVDALKSDKkVRTIIIRSEVPG-IFCAGADLKERAKMHSSEVG---PFVSKIRAvindIANLPVPTIAAIDGLALGGGLE 80
Cdd:PRK11423  39 ALSDLNRPE-IRVVILRAPSGSkVWSAGHDIHELPSGGRDPLSyddPLRQILRM----IQKFPKPVIAMVEGSVWGGAFE 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  81 LALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAYr 160
Cdd:PRK11423 114 LIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQRALAVGILNHVVEVEELEDFTL- 192

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159 161 kalDLAREFLPQGPVAMRVAK-----LAINQGMEVDL---VTGLAieeacyAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK11423 193 ---QMAHHISEKAPLAIAVIKeqlrvLGEAHPMNPDEferIQGLR------RAVYDSEDYQEGMNAFLEKRKPVFVGH 261
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 2-230 4.71e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 91.13  E-value: 4.71e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKsDKKVRTIIIRSEVPGiFCAGADLKER---AKMHSSEVGPFVSKIRA-VINDIANLPVPTIAAIDGLALGG 77
Cdd:PRK08140  36 LREALDQVE-DDGARALLLTGAGRG-FCAGQDLADRdvtPGGAMPDLGESIETFYNpLVRRLRALPLPVIAAVNGVAAGA 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  78 GLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEqnqegDA 157
Cdd:PRK08140 114 GANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARALGLALLGEKLSAEQAEQWGLIWRVVD-----DA 188

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672081159 158 AYR-KALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK08140 189 ALAdEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERDLQREAGRSADYAEGVSAFLEKRAPRFTGR 262
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 27-185 8.83e-22

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 89.51  E-value: 8.83e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  27 IFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAII 106
Cdd:PRK05869  63 IFSAGDDMPELRTLSAQEADTAARVRQQAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLA 142

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 107 PGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAIN 185
Cdd:PRK05869 143 PSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDEMVAP----DDVYDAAAAWARRFLDGPPHALAAAKAGIS 217
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
2-229 9.26e-22

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 90.12  E-value: 9.26e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLK-ERAKMHSSEVGPFVS--KIRAVINDIANLPVPTIAAIDGLALGGG 78
Cdd:PRK07468  37 LTTAARRLAADAAVRVVVLTGAGKS-FCAGGDLGwMRAQMTADRATRIEEarRLAMMLKALNDLPKPLIGRIQGQAFGGG 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  79 LELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRaIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEgDAA 158
Cdd:PRK07468 116 VGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFMSARLFDAEEAVRLGLLSRVVPAERL-DAA 193

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 159 YRKALdlaREFLPQGPVAMRVAK-LAINQGMEVDlvtglaieEACYAQTIS-------TKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK07468 194 VEAEV---TPYLSCAPGAVAAAKaLVRALGAPID--------EAVIDATIEaladtweTEEAREGIAAFFDKRAPAWRG 261
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
2-229 7.59e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 88.11  E-value: 7.59e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERA----KMHSSEVG----PFVSKIR---AVINDIANLPVPTIAAI 70
Cdd:PRK06142  38 LPEIFRWLDADPEVRAVVLSGSGKH-FSYGIDLPAMAgvfgQLGKDGLArprtDLRREILrlqAAINAVADCRKPVIAAV 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  71 DGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLE 150
Cdd:PRK06142 117 QGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIGDGHLRELALTGRDIDAAEAEKIGLVNRVYD 196

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 151 qnqEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK06142 197 ---DADALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHRVADGLRYVATWNAAMLPSKDLTEAIAAHMEKRPPEFTG 272
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 2-201 7.30e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 85.03  E-value: 7.30e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKERAKMHSSEVGPFVSK--IRAVindiANLPVPTIAAIDGLALGGGL 79
Cdd:PRK06190  36 LFAALAEADADDDVDVVVLTGADP-AFCAGLDLKELGGDGSAYGAQDALPnpSPAW----PAMRKPVIGAINGAAVTGGL 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  80 ELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAay 159
Cdd:PRK06190 111 ELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDAADALRAGLVTEVVPHDELLPR-- 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 672081159 160 rkALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEA 201
Cdd:PRK06190 189 --ARRLAASIAGNNPAAVRALKASYDDGAAAQTGDALALEAE 228
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
9-163 1.89e-19

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 86.49  E-value: 1.89e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   9 LKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVS-KIRAVINDIANLPVPTIAAIDGLALGGGLELALACDI 87
Cdd:PRK11154  46 LREDKELKGVVFISGKPDNFIAGADINMLAACKTAQEAEALArQGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHY 125

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159  88 RVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAYRKAL 163
Cdd:PRK11154 126 RVCTDDPKtvLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGKQLRAKQALKLGLVDDVVPHSILLEVAVELAK 203
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 2-181 2.33e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 83.55  E-value: 2.33e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:PRK06143  39 LTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISRLRDLCDAVRHFPVPVIARIPGWCLGGGLEL 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  82 ALACDIRVAASSAKMGLVETKLAiIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEqNQEGDAAYRK 161
Cdd:PRK06143 119 AAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLLLTGETIDAAQALAWGLVDRVVP-LAELDAAVER 196

                        170       180
                 ....*....|....*....|
gi 672081159 162 aldLAREFLPQGPVAMRVAK 181
Cdd:PRK06143 197 ---LAASLAGCGPQALRQQK 213
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
2-229 2.62e-19

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 83.59  E-value: 2.62e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMHSSEvGPFVS---KIRAVINDIANLPVPTIAAIDGLALGGG 78
Cdd:PRK06495  35 LIAVFDEISERPDVRVVVLTGA-GKVFCAGADLKGRPDVIKGP-GDLRAhnrRTRECFHAIRECAKPVIAAVNGPALGAG 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  79 LELALACDIRVAASSAKMGLVETKLAIIpggGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLeqnqEGDAA 158
Cdd:PRK06495 113 LGLVASCDIIVASENAVFGLPEIDVGLA---GGGKHAMRLFGHSLTRRMMLTGYRVPAAELYRRGVIEACL----PPEEL 185

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672081159 159 YRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK06495 186 MPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITAKLAKTEDAKEAQRAFLEKRPPVFKG 256
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
15-167 6.46e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 82.37  E-value: 6.46e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  15 VRTIIIRSEVPGiFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSA 94
Cdd:PRK08150  45 VRAVVLHGEGDH-FCAGLDLSELRERDAGEGMHHSRRWHRVFDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADEST 123

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672081159  95 KMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQegdaAYRKALDLAR 167
Cdd:PRK08150 124 YFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYDAQEGERLGLAQYLVPAGE----ALDKAMELAR 192
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
8-229 8.42e-19

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 82.32  E-value: 8.42e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   8 ALKSDKKVRTIIIRSEVPGiFCAGADLKE----RAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELAL 83
Cdd:PRK08258  55 ELVYADDVKAVVLTGAGGN-FCSGGDVHEiigpLTKMDMPELLAFTRMTGDLVKAMRACPQPIIAAVDGVCAGAGAILAM 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  84 ACDIRVAASSAKMGLVETK--LAiipGG--GGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAY 159
Cdd:PRK08258 134 ASDLRLGTPSAKTAFLFTRvgLA---GAdmGACALLPRIIGQGRASELLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQ 210

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672081159 160 RKALDLAReflpqGPV-AMRVAKLAINQgmEVDLVTGLAIEEACYAQTI--STKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK08258 211 ALARRLAA-----GPTfAHGMTKTMLHQ--EWDMGLEEAIEAEAQAQAIcmQTEDFRRAYEAFVAKRKPVFEG 276
PLN02888 PLN02888
enoyl-CoA hydratase
 2-199 1.89e-18

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 81.34  E-value: 1.89e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLkerakmhSSEVGPFVSKIRAVIND----IANLPVPTIAAIDGLALGG 77
Cdd:PLN02888  42 LAAAFKRLDEDDSVKVIILTGSGRA-FCSGVDL-------TAAEEVFKGDVKDVETDpvaqMERCRKPIIGAINGFAITA 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  78 GLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQegda 157
Cdd:PLN02888 114 GFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMPLTAETAERWGLVNHVVEESE---- 189

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 672081159 158 AYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIE 199
Cdd:PLN02888 190 LLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLE 231
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
85-229 2.52e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 80.78  E-value: 2.52e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  85 CDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEgdaaYRKALD 164
Cdd:PRK06563 114 ADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDEFDAQEALRLGLVQEVVPPGEQ----LERAIE 189

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672081159 165 LAREFLPQGPVAMRV----AKLAINQGMEVdlvtglAIEE--ACYAQTISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK06563 190 LAERIARAAPLGVQAtlasARAAVREGEAA------AAAQlpPELRPLFTSEDAKEGVQAFLERRPARFKG 254
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
2-229 6.87e-18

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 79.78  E-value: 6.87e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDK-KVRTIIIRSEVPGiFCAGADLKER---AKMHSSEVG----------PFVSKIRavindiaNLPVPTI 67
Cdd:PRK05981  36 LAEALDAIEDGKaEVRCLVLTGAGRG-FCTGANLQGRgsgGRESDSGGDagaaletayhPFLRRLR-------NLPCPIV 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  68 AAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISH 147
Cdd:PRK05981 108 TAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAMELSLLGEKLPAETALQWGLVNR 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159 148 VLEQNQEGDAAYRKALDLAReflpqGP-VAMRVAKLAINQGMEVDLVTGLAIEeaCYAQTI--STKDRLEGLLAFKEKRP 224
Cdd:PRK05981 188 VVDDAELMAEAMKLAHELAN-----GPtVALGLIRKLYWDSPENDFEEQLNLE--REAQRIagKTEDFKEGVGAFLQKRP 260


                 ....*
gi 672081159 225 PRYKG 229
Cdd:PRK05981 261 AQFKG 265
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 1-230 2.01e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 78.54  E-value: 2.01e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   1 MLSKAVDALK----SDKKVrtIIIRSEVPGiFCAGADLKERAKMHSSEVGPFVSK-IRAVINDIANLPVPTIAAIDGLAL 75
Cdd:PRK07659  34 MLKELLQALKevaeSSAHI--VVLRGNGRG-FSAGGDIKMMLSSNDESKFDGVMNtISEIVVTLYTMPKLTISAIHGPAA 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  76 GGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEqnQEG 155
Cdd:PRK07659 111 GLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGKKLSATEALDLGLIDEVIG--GDF 188

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672081159 156 DAAYRKALDlarEFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK07659 189 QTAAKQKIS---EWLQKPLKAMIETKQIYCELNRSQLEQVLQLEKRAQYAMRQTADHKEGIRAFLEKRLPVFKGE 260
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 2-230 4.78e-17

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 77.67  E-value: 4.78e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKE-RAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLE 80
Cdd:PRK08139  43 LQAALDAIAADPSVRVVVLAAAGK-AFCAGHDLKEmRAARGLAYFRALFARCSRVMQAIVALPQPVIARVHGIATAAGCQ 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  81 LALACDIRVAASSAKMGLVETKLAII---PGGGgtqrLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDA 157
Cdd:PRK08139 122 LVASCDLAVAADTARFAVPGVNIGLFcstPMVA----LSRNVPRKQAMEMLLTGEFIDAATAREWGLVNRVVPADALDAA 197

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672081159 158 AYRkaldLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK08139 198 VAR----LAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYAYAGDVMAENMMAEDAEEGIDAFLEKRPPEWRGR 266
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 2-227 1.30e-16

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 76.48  E-value: 1.30e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVrTIIIRSEVPGIFCAGADLKE----RAKMHSSEVGPFVSKIR-------AVINDIANLPVPTIAAI 70
Cdd:PLN02664  40 FPKALSSLDQNPNV-SVIILSGAGDHFCSGIDLKTlnsiSEQSSSGDRGRSGERLRrkikflqDAITAIEQCRKPVIAAI 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  71 DGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLE 150
Cdd:PLN02664 119 HGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELALTGRRFSGSEAKELGLVSRVFG 198

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672081159 151 QNQEGDAAYRKaldLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRY 227
Cdd:PLN02664 199 SKEDLDEGVRL---IAEGIAAKSPLAVTGTKAVLLRSRELSVEQGLDYVATWNSAMLVSDDLNEAVSAQIQKRKPVF 272
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 12-229 2.83e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 75.06  E-value: 2.83e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  12 DKKVRTIIIRSEVPgIFCAGADLKERAKMHSsevgpFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAA 91
Cdd:PRK07854  41 DESARAIVLTGQGT-VFCAGADLSGDVYADD-----FPDALIEMLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVA 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  92 SSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLishvleQNQEGDAAyrKALDLAREFLP 171
Cdd:PRK07854 115 PEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRARAMLLGAEKLTAEQALATGM------ANRIGTLA--DAQAWAAEIAG 186

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159 172 QGPVAMRVAKLAINQGMEVDLVTglAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK07854 187 LAPLALQHAKRVLNDDGAIEEAW--PAHKELFDKAWASQDAIEAQVARIEKRPPKFQG 242
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 2-150 5.34e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 74.38  E-value: 5.34e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLEL 81
Cdd:PRK05870  35 LRAAVAAAEADPDVHALVVTGAGKA-FCAGADLTALGAAPGRPAEDGLRRIYDGFLAVASCPLPTIAAVNGAAVGAGLNL 113

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159  82 ALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLE 150
Cdd:PRK05870 114 ALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMRFDAEAAVRHGLALMVAD 182
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
26-199 9.29e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 71.08  E-value: 9.29e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  26 GIFCAGADLK-----ERAKMHSSEVGPF-VSKIRavindianLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLV 99
Cdd:PRK08259  58 GTFCAGADLKavgtgRGNRLHPSGDGPMgPSRMR--------LSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVF 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159 100 ETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAYRKALDLARefLPQgpVAMRV 179
Cdd:PRK08259 130 CRRWGVPLIDGGTVRLPRLIGHSRAMDLILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAA--FPQ--TCLRA 205

                        170       180
                 ....*....|....*....|
gi 672081159 180 AKLAINQGMEVDLVTGLAIE 199
Cdd:PRK08259 206 DRLSALEQWGLPEEAALANE 225
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
12-229 9.59e-15

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 71.21  E-value: 9.59e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  12 DKKVRTIIIRSEVPGiFCAGADLKERAKMHSS-EVGPFVSK-IRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRV 89
Cdd:PRK07327  54 DPDVRVVLIRGEGKA-FSAGGDLALVEEMADDfEVRARVWReARDLVYNVINCDKPIVSAIHGPAVGAGLVAALLADISI 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  90 AASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnqegDAAYRKALDLAREf 169
Cdd:PRK07327 133 AAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLLLCEPVSGEEAERIGLVSLAVDD----DELLPKALEVAER- 207

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672081159 170 LPQG-PVAMRVAKLAINQGMEV---DLVTGLAIEEACYAqtisTKDRLEGLLAFKEKRPPRYKG 229
Cdd:PRK07327 208 LAAGsQTAIRWTKYALNNWLRMagpTFDTSLALEFMGFS----GPDVREGLASLREKRAPDFPG 267
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 2-208 2.56e-14

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 71.41  E-value: 2.56e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159    2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVIND-IANLPVPTIAAIDGLALGGGLE 80
Cdd:TIGR02441  46 FKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEGQEMFErIEKSQKPIVAAISGSCLGGGLE 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   81 LALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGdaa 158
Cdd:TIGR02441 126 LALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIRADRAKKMGIVDQLVDPLGPG--- 202

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 672081159  159 YRKALDLAREFLPQgpVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIS 208
Cdd:TIGR02441 203 LKPAEENTIEYLEE--VAVKFAQGLANGKLSINRDKGLVHKITQYVMTNP 250
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
2-227 1.40e-13

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 67.78  E-value: 1.40e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIrSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRAVIN---DIANLPVPTIAAIDGLALGGG 78
Cdd:PRK07827  38 LHDGLRAAAADPAVRAVVL-THTGGTFCAGADLSEAGGGGGDPYDAAVARAREMTAllrAIVELPKPVIAAIDGHVRAGG 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  79 LELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARvLDGQEAKAVGLIShvlEQNQEGDAA 158
Cdd:PRK07827 117 FGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAARYYLTGEK-FGAAEAARIGLVT---AAADDVDAA 192

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159 159 YRKALDLAREFLPQGPVAM-RVAKLAINQGMEVDLVTgLAIEEacyAQTISTKDRLEGLLAFKEKRPPRY 227
Cdd:PRK07827 193 VAALLADLRRGSPQGLAESkALTTAAVLAGFDRDAEE-LTEES---ARLFVSDEAREGMTAFLQKRPPRW 258
PLN02921 PLN02921
naphthoate synthase
 2-227 2.17e-12

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 65.19  E-value: 2.17e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKmhSSEVGPFVSKIRAVIN---DIANLPVPTIAAIDGLALGGG 78
Cdd:PLN02921  99 LQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGK--DGYVGPDDAGRLNVLDlqiQIRRLPKPVIAMVAGYAVGGG 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  79 LELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQ-EGDA 157
Cdd:PLN02921 177 HILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLARFYTASEALKMGLVNTVVPLDElEGET 256

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672081159 158 AyrkalDLAREFLPQGPVAMRVAKLAINQGMevDLVTGLAiEEACYAQTI--STKDRLEGLLAFKEKRPPRY 227
Cdd:PLN02921 257 V-----KWCREILRNSPTAIRVLKSALNAAD--DGHAGLQ-ELGGNATLLfyGSEEGNEGRTAYLEGRAPDF 320
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 2-228 2.52e-12

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 64.53  E-value: 2.52e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKER--------AKMHSSEVGPFVSKIRAvindianLPVPTIAAIDGL 73
Cdd:PRK07396  45 MIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRgyggyvddDGVPRLNVLDLQRLIRT-------CPKPVIAMVAGY 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  74 ALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHV--LEQ 151
Cdd:PRK07396 118 AIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFLCRQYDAQEALDMGLVNTVvpLAD 197

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672081159 152 NQEgdaayrKALDLAREFLPQGPVAMRVAKLAINQgmEVDLVTGLAiEEACYAQTI--STKDRLEGLLAFKEKRPPRYK 228
Cdd:PRK07396 198 LEK------ETVRWCREMLQNSPMALRCLKAALNA--DCDGQAGLQ-ELAGNATMLfyMTEEAQEGRNAFNEKRQPDFS 267
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 2-230 6.07e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 63.26  E-value: 6.07e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLkerakmhSSEVGPFVSKIRA----VINDIANLPVPTIAAIDGLALGG 77
Cdd:PRK06072  32 FISKLKQINADPKIRVVIVTGEGRA-FCVGADL-------SEFAPDFAIDLREtfypIIREIRFSDKIYISAINGVTAGA 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  78 GLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELI----FSArvldgQEAKAVGLISHVleqnq 153
Cdd:PRK06072 104 CIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEILVlggeFTA-----EEAERWGLLKIS----- 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159 154 egDAAYRKALDLAREFLpQGPVAMRVA-KLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK06072 174 --EDPLSDAEEMANRIS-NGPFQSYIAaKRMINLVLYNDLEEFLEYESAIQGYLGKTEDFKEGISSFKEKREPKFKGI 248
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
2-185 2.21e-11

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 61.53  E-value: 2.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAkmHSSEVGPFVSKIR---AVINDIANLPVPTIAAIDGLALGGG 78
Cdd:PRK07938  33 LADAITAAGADPDTRVVVLRAEGRG-FNAGVDIKELQ--ATPGFTALIDANRgcfAAFRAVYECAVPVIAAVHGFCLGGG 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  79 LELALACDIRVAASSAKMGLVETKLAIIpgGGGTQrLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAa 158
Cdd:PRK07938 110 IGLVGNADVIVASDDATFGLPEVDRGAL--GAATH-LQRLVPQHLMRALFFTAATITAAELHHFGSVEEVVPRDQLDEA- 185

                        170       180
                 ....*....|....*....|....*..
gi 672081159 159 yrkALDLAREFLPQGPVAMRVAKLAIN 185
Cdd:PRK07938 186 ---ALEVARKIAAKDTRVIRAAKEALN 209
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 2-227 5.23e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 61.00  E-value: 5.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKM-HSSEVGPFVSKIRA------VINDIANLPVPTIAAIDGLA 74
Cdd:PRK05864  42 LKEALAEVSYDNSVRVVVLTGAGRG-FSSGADHKSAGVVpHVEGLTRPTYALRSmellddVILALRRLHQPVIAAVNGPA 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  75 LGGGLELALACDIRVAASSAKM-------GLVETKLaiipggGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISH 147
Cdd:PRK05864 121 IGGGLCLALAADIRVASSSAYFraaginnGLTASEL------GLSYLLPRAIGSSRAFEIMLTGRDVDAEEAERIGLVSR 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159 148 VLEQNQEGDAAYRKALDLAREFLPqgpvAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIS--TKDRLEGLLAFKEKRPP 225
Cdd:PRK05864 195 QVPDEQLLDTCYAIAARMAGFSRP----GIELTKRTLWSGLDAASLEAHMQAEGLGQLFVRllTANFEEAVAARAEKRPP 270


                 ..
gi 672081159 226 RY 227
Cdd:PRK05864 271 VF 272
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 2-230 5.39e-11

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 60.59  E-value: 5.39e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADL---KERAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGG 78
Cdd:PRK05674  38 LILALDQVQSDASLRFLLLRGRGRH-FSAGADLawmQQSADLDYNTNLDDARELAELMYNLYRLKIPTLAVVQGAAFGGA 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  79 LELALACDIRVAASSAKMGLVETKLAIIPGGGGTqRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnQEGDAA 158
Cdd:PRK05674 117 LGLISCCDMAIGADDAQFCLSEVRIGLAPAVISP-FVVKAIGERAARRYALTAERFDGRRARELGLLAESYPA-AELEAQ 194

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672081159 159 YRKALDlarEFLPQGPVAMRVAKLAINQGMEVDLVTGL-AIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE 230
Cdd:PRK05674 195 VEAWIA---NLLLNSPQALRASKDLLREVGDGELSPALrRYCENAIARIRVSAEGQEGLRAFLEKRTPAWQTD 264
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
 1-181 1.62e-10

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 59.54  E-value: 1.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   1 MLSKAVDALKSDKK--VRTIIIRSEVPGIFCAGADL---------KERAKM-----------HSSEVGPfvskiravind 58
Cdd:PRK08788  50 NLQRAIRQRLDDSGlpVDFWVLASDVPGVFNLGGDLalfaeliraGDRDALlayaracvdgvHAFHRGF----------- 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  59 iaNLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQE 138
Cdd:PRK08788 119 --GAGAISIALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPKLAEELILSGKLYTAEE 196

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 672081159 139 AKAVGLISHVLEQNQeGDAAYRKALDLAREfLPQGPVAMRVAK 181
Cdd:PRK08788 197 LHDMGLVDVLVEDGQ-GEAAVRTFIRKSKR-KLNGWRAMLRAR 237
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 2-190 1.37e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 56.89  E-value: 1.37e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKMHSSEVGPF---VSKIRAVIND-------------------I 59
Cdd:PRK08290  36 LDAAFRRAEADDAVRVIVLAGAGKH-FSAGHDLGSGTPGRDRDPGPDqhpTLWWDGATKPgveqryarewevylgmcrrW 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  60 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIipggGGTQRL--PRAIGMALAKELIFSARVLDGQ 137
Cdd:PRK08290 115 RDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI----PGVEYFahPWELGPRKAKELLFTGDRLTAD 190

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 672081159 138 EAKAVGLISHV-----LEQnqegdaayrKALDLAREFLPQGPVAMRVAKLAINQGMEV 190
Cdd:PRK08290 191 EAHRLGMVNRVvprdeLEA---------ETLELARRIAAMPPFGLRLTKRAVNQTLDA 239
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 2-184 9.14e-09

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 54.50  E-value: 9.14e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEV-PGIFCAGADLKE--RAKMHSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGG 78
Cdd:PLN03214  43 LDDALTALENDPTVRGVVFASGLrRDVFTAGNDIAElyAPKTSAARYAEFWLTQTTFLVRLLRSRLATVCAIRGACPAGG 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  79 LELALACDIRVAASSAKMGLVETKLAI-IPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDA 157
Cdd:PLN03214 123 CAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRKVAESLLLRGRLVRPAEAKQLGLIDEVVPAAALMEA 202

                        170       180
                 ....*....|....*....|....*..
gi 672081159 158 AYRKaldlAREFLPQGPVAMRVAKLAI 184
Cdd:PLN03214 203 AASA----MERALKLPSAARAATKALL 225
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 2-167 1.59e-08

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 53.43  E-value: 1.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLK-----ERAKMHSSEVgPFVSKIravindiANLPVPTIAAIDGLALG 76
Cdd:PRK07110  37 LHEAFDTIAQDPRYKVVILTG-YPNYFATGGTQEgllslQTGKGTFTEA-NLYSLA-------LNCPIPVIAAMQGHAIG 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  77 GGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEGD 156
Cdd:PRK07110 108 GGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLLTARYYRGAELKKRGVPFPVLPRAEVLE 187

                        170
                 ....*....|.
gi 672081159 157 AAYRKALDLAR 167
Cdd:PRK07110 188 KALELARSLAE 198
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
2-228 5.57e-08

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 52.33  E-value: 5.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIR----SEVPGI--FCAGADLKERA----KMHSSEVGPFVSKIRA-------VINDIANLPV 64
Cdd:PRK08321  57 LYRALDHARMSPDVGCVLLTgngpSPKDGGwaFCSGGDQRIRGrdgyQYAEGDEADTVDPARAgrlhileVQRLIRFMPK 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  65 PTIAAIDGLALGGGLELALACDIRVAASS-AKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVG 143
Cdd:PRK08321 137 VVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYSAEEAHDMG 216

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159 144 LISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINqgMEVD------LVTGLAIEEAcYAqtisTKDRLEGLL 217
Cdd:PRK08321 217 AVNAVVPHAELETE----ALEWAREINGKSPTAMRMLKYAFN--LTDDglvgqqLFAGEATRLA-YM----TDEAQEGRD 285

                        250
                 ....*....|.
gi 672081159 218 AFKEKRPPRYK 228
Cdd:PRK08321 286 AFLEKRDPDWS 296
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 85-192 1.28e-07

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 50.78  E-value: 1.28e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  85 CDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQNQEgDAAYRKald 164
Cdd:PRK09120 126 CDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYIMTGETFTGRKAAEMGLVNESVPLAQL-RARTRE--- 201

                         90       100
                 ....*....|....*....|....*...
gi 672081159 165 LAREFLPQGPVAMRVAKLAINQGMEVDL 192
Cdd:PRK09120 202 LAAKLLEKNPVVLRAAKDGFKRVRELTW 229
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 4-150 1.40e-07

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 50.89  E-value: 1.40e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   4 KAVDALKSDKKVRTIIIRSEVPgIFCAGADLKERAKMHSSEVGPFVSKIRAVINDIA----NLPVPTIAAIDGLALGGGL 79
Cdd:PRK07260  36 EALRLAEEDPSVRFLLINANGK-VFSVGGDLVEMKRAVDEDDVQSLVKIAELVNEISfaikQLPKPVIMCVDGAVAGAAA 114

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672081159  80 ELALACDIRVAASSAKM--GLVETKLAiiPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLE 150
Cdd:PRK07260 115 NMAVAADFCIASTKTKFiqAFVGVGLA--PDAGGLFLLTRAIGLNRATHLAMTGEALTAEKALEYGFVYRVAE 185
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
2-190 1.41e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 45.03  E-value: 1.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAK-MHSSEVGPFVSKIRAVINDIANLP----------------- 63
Cdd:PRK08272  42 LRAAVERADLDPGVHVILVSGAGKG-FCAGYDLSAYAEgSSSGGGGGAYPGKRQAVNHLPDDPwdpmidyqmmsrfvrgf 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  64 -------VPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGG------GTQRlpraigmalAKELIFS 130
Cdd:PRK08272 121 mslwhahKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTRVWGVPATGmwayrlGPQR---------AKRLLFT 191

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159 131 ARVLDGQEAKAVGLISHVLEQNQEGDAAYRKALDLAreFLPQGPVAMrvAKLAINQGMEV 190
Cdd:PRK08272 192 GDCITGAQAAEWGLAVEAVPPEELDERTERLVERIA--AVPVNQLAM--VKLAVNSALLQ 247
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
2-219 8.60e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 42.47  E-value: 8.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLKE--RAKMHSSEVGPfvsKIRAVINDIANLPVPTIAAIDGLALGGGL 79
Cdd:PRK06023  38 MAKALKAADADDAIRAHVFLG-TEGCFSAGNDMQDflAAAMGGTSFGS---EILDFLIALAEAEKPIVSGVDGLAIGIGT 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  80 ELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMALAKELIFSARVLDGQEAKAVGLISHVLEQnqegDAAY 159
Cdd:PRK06023 114 TIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSAEAAQEAGLIWKIVDE----EAVE 189

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159 160 RKALDLAREFLPQGPVAMRVAKlAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAF 219
Cdd:PRK06023 190 AETLKAAEELAAKPPQALQIAR-DLMRGPREDILARIDEEAKHFAARLKSAEARAAFEAF 248
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 2-150 9.87e-05

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 42.46  E-value: 9.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159    2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKM----HSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLalgg 77
Cdd:pfam16113  23 LLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAakagGGEAGRDFFREEYRLNYLIATYPKPYVALMDGIvmgg 102

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672081159   78 glelalaCDIRVAASSAKMGLVETKLAIIPGGGGT---QRLPRAIGMALAkeliFSARVLDGQEAKAVGLISHVLE 150
Cdd:pfam16113 103 gvglsvhGSFRVVTERTRFAMPETAIGLFPDVGGSyflSRLPGELGLYLA----LTGARLNGADALAAGLATHYVP 174
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 2-218 2.84e-03

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 38.26  E-value: 2.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159   2 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKE-----RAKMHSSEVGPFVSKIRavIN-DIANLPVPTIAAIDGLAL 75
Cdd:PRK05617  35 IDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRAlyeaaRAGDPLAADRFFREEYR--LNaLIARYPKPYIALMDGIVM 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672081159  76 GGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGmALAKELIFSARVLDGQEAKAVGLISHVLEQNQEg 155
Cdd:PRK05617 113 GGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPG-ALGTYLALTGARISAADALYAGLADHFVPSADL- 190

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672081159 156 dAAYRKALDLAREFLPQGPVAMRVAKLAINQGmEVDLVTGLAIEEACYAQtistkDRLEGLLA 218
Cdd:PRK05617 191 -PALLDALISLRWDSGADVVDAALAAFATPAP-ASELAAQRAWIDECFAG-----DTVEDIIA 246
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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