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Conserved domains on  [gi|672073054|ref|XP_008767473|]
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CAP-Gly domain-containing linker protein 1 isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 2.36e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.36  E-value: 2.36e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054   213 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.35e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


:

Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.35e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1047-1919 6.25e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.45  E-value: 6.25e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1047 QKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKAKSLTYL--------LTSAKKEIEVMSEELRGLKSEKQLFAQEASA 1118
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1119 LKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQE 1198
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1199 ELlkmhmekdsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQvkkltaenmvlVKDKDDVIQKLQSAYEELV 1278
Cdd:TIGR02168  338 EL--------------AELEEKLEELKEELESLEAELEELEAELEELESR-----------LEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1279 KDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENllQSNRDLQFEKDTLRQGQEKLSASLEAtlqvkqlLSTEA 1358
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELER-------LEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1359 ETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEeiktcraitdseciqllhEKESLAASERALLAEKEELLNENRVI 1438
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQE------------------NLEGFSEGVKALLKNQSGLSGILGVL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1439 TEKLNKHSEEVTRLEVSLNEKITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKY-- 1516
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVak 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1517 --EQEATNRRLAVQEkvkLLGNI---DALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTsmMQAKEdlnA 1591
Cdd:TIGR02168  606 dlVKFDPKLRKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS--ILERR---R 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1592 ELKTCCCEKNILLRDGLNLQEECQKLNEEIREIQQtlmlEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQ 1671
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1672 TENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTER 1751
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1752 AEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIREL 1831
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1832 ETLHSFTAAQ--TAEDAMQIMEQMTKEKTETLA-------------------SLEDTKQTNAKLQSELDTLKENNLKTVE 1890
Cdd:TIGR02168  914 RRELEELREKlaQLELRLEGLEVRIDNLQERLSeeysltleeaealenkiedDEEEARRRLKRLENKIKELGPVNLAAIE 993

                          890       900
                   ....*....|....*....|....*....
gi 672073054  1891 ELNKSKELLNEENQKMEEFKKEIETLKQA 1919
Cdd:TIGR02168  994 EYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 634-1349 4.55e-17

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 88.20  E-value: 4.55e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   634 QQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIES---LQSKQDSERSAHAKEMESMKAKLMKIIKEKeDSLE 710
Cdd:TIGR02169  173 EKALEELEE-VEENIERLDLIIDEKRQQLERLRREREKAERYqalLKEKREYEGYELLKEKEALERQKEAIERQL-ASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   711 AVKARLDTAEDQHLVEMEEMLSKLQEAEIKVKELEvlQAKYSEQTQVVGHLTSQLSVVEEQlldldalrkansegkleIE 790
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG--EEEQLRVKEKIGELEAEIASLERS-----------------IA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   791 TLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQ 870
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   871 TSMQDTVNKLH-------QKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQL 943
Cdd:TIGR02169  392 EKLEKLKREINelkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   944 TKMNDELRLKERSVEELQLKLTKANENAS--------------LLQKSI-GEVTLKAEQSQQEAAKKHEEEKKELENKLL 1008
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARaseervrggraveeVLKASIqGVHGTVAQLGSVGERYATAIEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1009 ELEKKMETSHYQCQDLKA------------KYEKASSETKIKHEEILQNFQKMLVDTEDKLKAA-QEANRD--LMQDMEE 1073
Cdd:TIGR02169  552 VVVEDDAVAKEAIELLKRrkagratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAfKYVFGDtlVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1074 LKSQ-----------------------ADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKL 1130
Cdd:TIGR02169  632 ARRLmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1131 IEVETKITLLQEDQQKLwsvNENLHLEKERIsEEKQVAEKRYQQEHRDKESlvvEREKLLKEINVTQEELLKMHMEKDSL 1210
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQL---EQEEEKLKERL-EELEEDLSSLEQEIENVKS---ELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1211 EASKVSMQvlIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLvkdkDDVIQKLQSAYEELVKDQKALVQEIED 1290
Cdd:TIGR02169  785 EARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL----EKEIQELQEQRIDLKEQIKSIEKEIEN 858

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672073054  1291 LTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLS--------------ASLEATLQ 1349
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEaqiekkrkrlselkAKLEALEE 931
CCDC158 super family cl37899
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 356-905 5.75e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


The actual alignment was detected with superfamily member pfam15921:

Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 68.22  E-value: 5.75e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   356 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALARDG-------HDQHVLELEAKMDQLRTMVEAADREKV 424
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   425 ELLNQLEEE---------KRKVEDLQFrvEEESITKGDLEQKSQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQR 495
Cdd:pfam15921  342 DKIEELEKQlvlanseltEARTERDQF--SQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRR 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   496 ELEDTRVATVSEKSRIM--------ELEKDLAL------RVQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEVT 561
Cdd:pfam15921  420 ELDDRNMEVQRLEALLKamksecqgQMERQMAAiqgkneSLEKVSSLTAQLESTK-----EMLRKVVEELTAKKMTLESS 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   562 HTDHQNEVTSLKDHFGTREEMfQKEIKALHAATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIASHQQA 636
Cdd:pfam15921  495 ERTVSDLTASLQEKERAIEAT-NAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALklqmaEKDKVIEILRQQIEN 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   637 MEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQhEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKaRL 716
Cdd:pfam15921  574 MTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ-EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVK-DI 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   717 DTAEDQHLVEMEEMLSKLQEAEikvKELEVLQAKYSEQTQVVGHLTSQLsvveeqlldldalrkansegKLEIETLRQQL 796
Cdd:pfam15921  652 KQERDQLLNEVKTSRNELNSLS---EDYEVLKRNFRNKSEEMETTTNKL--------------------KMQLKSAQSEL 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   797 EGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDT 876
Cdd:pfam15921  709 EQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580
                   ....*....|....*....|....*....
gi 672073054   877 VNKLHqkeeqfnMLSSELEKLRENLTDME 905
Cdd:pfam15921  789 AGELE-------VLRSQERRLKEKVANME 810
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1773-2074 6.93e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 6.93e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1773 EEVLKEKEKLE------ESYFVLQKEISQLaqtnshisaDLLEAQSENRTLRKDKSKLTLKIRELEtlhsftaaQTAEDA 1846
Cdd:COG1196   196 GELERQLEPLErqaekaERYRELKEELKEL---------EAELLLLKLRELEAELEELEAELEELE--------AELEEL 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1847 MQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQ 1926
Cdd:COG1196   259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1927 LSALQEENVKLAEELGRTRDEVTSHQK----LEEERSVLNNQLLEMKKRESEYRKDADEEKASLQKSISLTSALLTEKDA 2002
Cdd:COG1196   339 LEELEEELEEAEEELEEAEAELAEAEEalleAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672073054 2003 ELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDVQTEEDERAQ 2074
Cdd:COG1196   419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2171-2187 1.59e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.59e-07
                           10
                   ....*....|....*..
gi 672073054  2171 RPYCEICEMFGHWATNC 2187
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2131-2148 1.90e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


:

Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.90e-04
                           10
                   ....*....|....*...
gi 672073054  2131 RLFCDICDCFDlHDTEDC 2148
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 2.36e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.36  E-value: 2.36e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054   213 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.35e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.35e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 213-278 6.82e-28

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 108.06  E-value: 6.82e-28
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672073054    213 IGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPKYGLFAPVHKVT 278
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 60-125 3.53e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 3.53e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672073054     60 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1047-1919 6.25e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.45  E-value: 6.25e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1047 QKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKAKSLTYL--------LTSAKKEIEVMSEELRGLKSEKQLFAQEASA 1118
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1119 LKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQE 1198
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1199 ELlkmhmekdsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQvkkltaenmvlVKDKDDVIQKLQSAYEELV 1278
Cdd:TIGR02168  338 EL--------------AELEEKLEELKEELESLEAELEELEAELEELESR-----------LEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1279 KDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENllQSNRDLQFEKDTLRQGQEKLSASLEAtlqvkqlLSTEA 1358
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELER-------LEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1359 ETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEeiktcraitdseciqllhEKESLAASERALLAEKEELLNENRVI 1438
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQE------------------NLEGFSEGVKALLKNQSGLSGILGVL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1439 TEKLNKHSEEVTRLEVSLNEKITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKY-- 1516
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVak 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1517 --EQEATNRRLAVQEkvkLLGNI---DALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTsmMQAKEdlnA 1591
Cdd:TIGR02168  606 dlVKFDPKLRKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS--ILERR---R 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1592 ELKTCCCEKNILLRDGLNLQEECQKLNEEIREIQQtlmlEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQ 1671
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1672 TENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTER 1751
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1752 AEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIREL 1831
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1832 ETLHSFTAAQ--TAEDAMQIMEQMTKEKTETLA-------------------SLEDTKQTNAKLQSELDTLKENNLKTVE 1890
Cdd:TIGR02168  914 RRELEELREKlaQLELRLEGLEVRIDNLQERLSeeysltleeaealenkiedDEEEARRRLKRLENKIKELGPVNLAAIE 993

                          890       900
                   ....*....|....*....|....*....
gi 672073054  1891 ELNKSKELLNEENQKMEEFKKEIETLKQA 1919
Cdd:TIGR02168  994 EYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 634-1349 4.55e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 88.20  E-value: 4.55e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   634 QQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIES---LQSKQDSERSAHAKEMESMKAKLMKIIKEKeDSLE 710
Cdd:TIGR02169  173 EKALEELEE-VEENIERLDLIIDEKRQQLERLRREREKAERYqalLKEKREYEGYELLKEKEALERQKEAIERQL-ASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   711 AVKARLDTAEDQHLVEMEEMLSKLQEAEIKVKELEvlQAKYSEQTQVVGHLTSQLSVVEEQlldldalrkansegkleIE 790
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG--EEEQLRVKEKIGELEAEIASLERS-----------------IA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   791 TLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQ 870
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   871 TSMQDTVNKLH-------QKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQL 943
Cdd:TIGR02169  392 EKLEKLKREINelkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   944 TKMNDELRLKERSVEELQLKLTKANENAS--------------LLQKSI-GEVTLKAEQSQQEAAKKHEEEKKELENKLL 1008
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARaseervrggraveeVLKASIqGVHGTVAQLGSVGERYATAIEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1009 ELEKKMETSHYQCQDLKA------------KYEKASSETKIKHEEILQNFQKMLVDTEDKLKAA-QEANRD--LMQDMEE 1073
Cdd:TIGR02169  552 VVVEDDAVAKEAIELLKRrkagratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAfKYVFGDtlVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1074 LKSQ-----------------------ADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKL 1130
Cdd:TIGR02169  632 ARRLmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1131 IEVETKITLLQEDQQKLwsvNENLHLEKERIsEEKQVAEKRYQQEHRDKESlvvEREKLLKEINVTQEELLKMHMEKDSL 1210
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQL---EQEEEKLKERL-EELEEDLSSLEQEIENVKS---ELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1211 EASKVSMQvlIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLvkdkDDVIQKLQSAYEELVKDQKALVQEIED 1290
Cdd:TIGR02169  785 EARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL----EKEIQELQEQRIDLKEQIKSIEKEIEN 858

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672073054  1291 LTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLS--------------ASLEATLQ 1349
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEaqiekkrkrlselkAKLEALEE 931
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 656-1297 7.62e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.75  E-value: 7.62e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  656 AELKTQIERLR------LDYQHEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEdqhlVEMEE 729
Cdd:COG1196   196 GELERQLEPLErqaekaERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE----AELEE 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  730 MLSKLQEAEikvKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEgklEIETLRQQLEGAEKQIKNLEME 809
Cdd:COG1196   272 LRLELEELE---LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE---ELAELEEELEELEEELEELEEE 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  810 RNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNM 889
Cdd:COG1196   346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  890 LSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEImkmsGDNSSQLTKMNDELRLKERSVEELQLKLTKANE 969
Cdd:COG1196   426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL----LEEAALLEAALAELLEELAEAAARLLLLLEAEA 501

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  970 NASLLQKSIGEVTLKAEQSQQEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEilQNFQKM 1049
Cdd:COG1196   502 DYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGR--ATFLPL 579

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1050 LVDTEDKLKAAQEANRDLMQDMEELKSQADKAKSLTYLL--TSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLL 1127
Cdd:COG1196   580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLgdTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG 659

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1128 SKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKMHMEK 1207
Cdd:COG1196   660 GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE 739

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1208 DSLEASKVSMQVLIEELRFCKDklmamSEKARAEKEQLEGQVKKLTAENMvlvkdkdDVIQklqsAYEELVKDQKALVQE 1287
Cdd:COG1196   740 ELLEEEELLEEEALEELPEPPD-----LEELERELERLEREIEALGPVNL-------LAIE----EYEELEERYDFLSEQ 803

                         650
                  ....*....|
gi 672073054 1288 IEDLTTEKKS 1297
Cdd:COG1196   804 REDLEEARET 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1288-1919 3.41e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 3.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1288 IEDLTTEKksaaEKQMNldntclTLKAERENLLQSnRDLQFEKDTLRQgqEKLSASLEATLQVKQLLSTEAETLRTQLDC 1367
Cdd:COG1196   191 LEDILGEL----ERQLE------PLERQAEKAERY-RELKEELKELEA--ELLLLKLRELEAELEELEAELEELEAELEE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1368 ATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSE 1447
Cdd:COG1196   258 LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1448 EVTRLEvslnekityltsekemacQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAV 1527
Cdd:COG1196   338 ELEELE------------------EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1528 QEKVKLLGNIDALKKELQQRKKENQELASSkcdlslmLKEAQTAKKNLEKEHTSMMQAKEDLNAELKtcccEKNILLRDG 1607
Cdd:COG1196   400 AQLEELEEAEEALLERLERLEEELEELEEA-------LAELEEEEEEEEEALEEAAEEEAELEEEEE----ALLELLAEL 468

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1608 LNLQEECQKLNEEIREIQQTLmLEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQK 1687
Cdd:COG1196   469 LEEAALLEAALAELLEELAEA-AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1688 VVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKRE 1767
Cdd:COG1196   548 LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1768 MMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAM 1847
Cdd:COG1196   628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672073054 1848 QIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELnkskELLNEENQKMEEFKKEIETLKQA 1919
Cdd:COG1196   708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA----LEELPEPPDLEELERELERLERE 775
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 211-271 5.67e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 71.25  E-value: 5.67e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672073054  211 LKIGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLF 271
Cdd:COG5244     4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1536-2112 1.12e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 70.48  E-value: 1.12e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1536 NIDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELKTCCCEKNILLRdglnLQEECQ 1615
Cdd:PRK03918  166 NLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE----LKEEIE 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1616 KLNEEIREIQQTlMLEKEARAKESESSLYESNKlhgRIVLLEEEIQGLRTCsEQLQTENFTLTQEKTNSEQKVVEIIKEK 1695
Cdd:PRK03918  242 ELEKELESLEGS-KRKLEEKIRELEERIEELKK---EIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDELREIEKRL 316

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1696 ELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLnhevavTERAEVLQDNKNLLaEKREMMLRNEEV 1775
Cdd:PRK03918  317 SRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHEL------YEEAKAKKEELERL-KKRLTGLTPEKL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1776 LKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLH--SFTAAQTAEdamqiMEQM 1853
Cdd:PRK03918  390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkELLEEYTAE-----LKRI 464

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1854 TKEKTETLASLEDTKQTNAKLQSELDTLKE--NNLKTVEELNKSKELLNEEN-QKMEEFKKEIETLKQAAAQKSQQLSAL 1930
Cdd:PRK03918  465 EKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSL 544

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1931 QEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLE------------MKKRESEYR-----KDADEEKASLQKSISLT 1993
Cdd:PRK03918  545 KKELEKLEELKKKLAELEKKLDELEEELAELLKELEElgfesveeleerLKELEPFYNeylelKDAEKELEREEKELKKL 624

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1994 SALLTEKDAELEKLRNEVTVLRGENASAKSLHSV--VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDVQTEEDE 2071
Cdd:PRK03918  625 EEELDKAFEELAETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|...
gi 672073054 2072 RAQES--QIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGE 2112
Cdd:PRK03918  705 EREKAkkELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 659-1364 1.53e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 70.15  E-value: 1.53e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   659 KTQIERLRLDYQHEIESLQSKQDSERSAHAKEMESMKAKLMKI------IKEKEDSLEAVKARLDTAEDQHLVEMEEMLS 732
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLqtklqeMQMERDAMADIRRRESQSQEDLRNQLQNTVH 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   733 KLQEAeiKVKELEVLQAKYSEQTQVVGHLTSQLSVVEE---QLLDLDAL--RKANSEGKLEIETLRQQLEGAEKQIKNLE 807
Cdd:pfam15921  153 ELEAA--KCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEirsILVDFEEAsgKKIYEHDSMSTMHFRSLGSAISKILRELD 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   808 MERNAESSKANSITKDL-----QGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSM----QDTVN 878
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLealksESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLeiiqEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   879 KLHQKEEQFNMLSSELEKLRENLTDMEAKFKEK-DEREDQLVKAKEKLENDIAE---IMKMSGDNSSQLTKMNDELRLKE 954
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRSELREAKRMYEDKiEELEKQLVLANSELTEARTErdqFSQESGNLDDQLQKLLADLHKRE 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   955 RsveelQLKLTKaNENASLLQKSIGEvTLKAEQSQQEaakkheeeKKELENKLLELEKKMETSHYQCQDlKAKYEKASSE 1034
Cdd:pfam15921  391 K-----ELSLEK-EQNKRLWDRDTGN-SITIDHLRRE--------LDDRNMEVQRLEALLKAMKSECQG-QMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1035 TKIKHEEILQNFQKMLVDTEDKLKAAQEanrDLMQDMEELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQ 1114
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEMLRKVVE---ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1115 EASALKLEKGSLLSKLIEVET-KITLLQEDQQklwsvnenLHLEKERISEEKQVAekryQQEHRDKESLVVEREKLLKEI 1193
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEAlKLQMAEKDKV--------IEILRQQIENMTQLV----GQHGRTAGAMQVEKAQLEKEI 599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1194 NVTQEELLKMHMEKDSLEASKVSMQVLIEELRFCKDKLM-AMSEKARA------EKEQLEGQVK-------KLTAENMVL 1259
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVnAGSERLRAvkdikqERDQLLNEVKtsrnelnSLSEDYEVL 679

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1260 VKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKS-------AAEKQMNLDNTcLTLKAERENLLQSNrdLQF---- 1328
Cdd:pfam15921  680 KRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSmegsdghAMKVAMGMQKQ-ITAKRGQIDALQSK--IQFleea 756

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 672073054  1329 ------EKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQ 1364
Cdd:pfam15921  757 mtnankEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQ 798
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1071-1918 3.05e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 69.23  E-value: 3.05e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1071 MEELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKLWSV 1150
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1151 NENLHLEKERISEEKQVAEKRYQQEHR--------DKESLVVEREKLLKEINVTQEELLKMHMEKDSLEASKVSMQVLIE 1222
Cdd:pfam02463  259 EIEKEEEKLAQVLKENKEEEKEKKLQEeelkllakEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1223 ELRFCKDKLMAMSEKARAEKEQLEGQVKKltaenmvLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQ 1302
Cdd:pfam02463  339 ELEKELKELEIKREAEEEEEEELEKLQEK-------LEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1303 MNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLSA---SLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDM 1379
Cdd:pfam02463  412 ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEeleKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLS 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1380 RQLQTSNTSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRLEVSLNEK 1459
Cdd:pfam02463  492 RQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALT 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1460 ITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKL--LGNI 1537
Cdd:pfam02463  572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKEsgLRKG 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1538 DALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEH---TSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEEC 1614
Cdd:pfam02463  652 VSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEilrRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQ 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1615 QKLNEEIREIQQTLMLEKEARAKESESSLYESNKLHGRIVLLEEEIqglrtcSEQLQTENFTLTQEKTNSEQKVVEIIKE 1694
Cdd:pfam02463  732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA------EEREKTEKLKVEEEKEEKLKAQEEELRA 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1695 KELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQdNKNLLAEKREMMLRNEE 1774
Cdd:pfam02463  806 LEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEE-LLQELLLKEEELEEQKL 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1775 VLKEKEKLEEsyfvlQKEISQLAQTNSHISADLLEAQSENRTLRKDK-SKLTLKIRELETLHSFTAAQTAEDAMQIMEQM 1853
Cdd:pfam02463  885 KDELESKEEK-----EKEEKKELEEESQKLNLLEEKENEIEERIKEEaEILLKYEEEPEELLLEEADEKEKEENNKEEEE 959

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054  1854 TKEKTETLASLEDTKQtnaklqsELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQ 1918
Cdd:pfam02463  960 ERNKRLLLAKEELGKV-------NLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
340-934 4.09e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.55  E-value: 4.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  340 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELaLARDGHDQHVLELEAKMDQLRTMVEAA 419
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  420 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLehariKELEQSLLFEKTKADKLQRELED 499
Cdd:PRK03918  258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL-----REIEKRLSRLEEEINGIEERIKE 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  500 TRvatvSEKSRIMELEKdlalrvqEVAELRRRLESSKPpgdvdmSLSLLQEISALQEKLEvthtdhqnevtSLKDHFGTR 579
Cdd:PRK03918  333 LE----EKEERLEELKK-------KLKELEKRLEELEE------RHELYEEAKAKKEELE-----------RLKKRLTGL 384

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  580 E-EMFQKEIKALHAATEKLSKENESLRSKldhankensdvialwKSKLETAIASHQQAMEELKVsfskgigtdsaefAEL 658
Cdd:PRK03918  385 TpEKLEKELEELEKAKEEIEEEISKITAR---------------IGELKKEIKELKKAIEELKK-------------AKG 436

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  659 KTQIERLRLDYQHEIESLQSkqdsersaHAKEMESMKAKLMKiIKEKEDSLEAVKARLDT--AEDQHLVEMEEMLSKLQE 736
Cdd:PRK03918  437 KCPVCGRELTEEHRKELLEE--------YTAELKRIEKELKE-IEEKERKLRKELRELEKvlKKESELIKLKELAEQLKE 507

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  737 AEIKVKE--LEVLQAKYSEQTQV---VGHLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEGAEKQIKNLEMERN 811
Cdd:PRK03918  508 LEEKLKKynLEELEKKAEEYEKLkekLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV 587

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  812 AESSKANSITKDLQGKELMLTSLQSNLnevnqvkETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQK-----EEQ 886
Cdd:PRK03918  588 EELEERLKELEPFYNEYLELKDAEKEL-------EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELekkysEEE 660

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 672073054  887 FNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMK 934
Cdd:PRK03918  661 YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 356-905 5.75e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 68.22  E-value: 5.75e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   356 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALARDG-------HDQHVLELEAKMDQLRTMVEAADREKV 424
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   425 ELLNQLEEE---------KRKVEDLQFrvEEESITKGDLEQKSQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQR 495
Cdd:pfam15921  342 DKIEELEKQlvlanseltEARTERDQF--SQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRR 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   496 ELEDTRVATVSEKSRIM--------ELEKDLAL------RVQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEVT 561
Cdd:pfam15921  420 ELDDRNMEVQRLEALLKamksecqgQMERQMAAiqgkneSLEKVSSLTAQLESTK-----EMLRKVVEELTAKKMTLESS 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   562 HTDHQNEVTSLKDHFGTREEMfQKEIKALHAATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIASHQQA 636
Cdd:pfam15921  495 ERTVSDLTASLQEKERAIEAT-NAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALklqmaEKDKVIEILRQQIEN 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   637 MEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQhEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKaRL 716
Cdd:pfam15921  574 MTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ-EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVK-DI 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   717 DTAEDQHLVEMEEMLSKLQEAEikvKELEVLQAKYSEQTQVVGHLTSQLsvveeqlldldalrkansegKLEIETLRQQL 796
Cdd:pfam15921  652 KQERDQLLNEVKTSRNELNSLS---EDYEVLKRNFRNKSEEMETTTNKL--------------------KMQLKSAQSEL 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   797 EGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDT 876
Cdd:pfam15921  709 EQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580
                   ....*....|....*....|....*....
gi 672073054   877 VNKLHqkeeqfnMLSSELEKLRENLTDME 905
Cdd:pfam15921  789 AGELE-------VLRSQERRLKEKVANME 810
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 60-121 9.55e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 67.02  E-value: 9.55e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672073054   60 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRP 121
Cdd:COG5244     6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 335-807 1.11e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  335 LTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRT 414
Cdd:COG1196   283 LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  415 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHAR------IKELEQSLLFEKT 488
Cdd:COG1196   363 AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELeeleeaLAELEEEEEEEEE 442

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  489 KADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESSKPPGDVDMSLSLLQEiSALQEKLEVTHTDHQNE 568
Cdd:COG1196   443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE-GFLEGVKAALLLAGLRG 521

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  569 VTSLKDHFGTREEMFQKEIKALHAA---------TEKLSKENESLRSK---------LDHANKENSDVIALWKSKLETAI 630
Cdd:COG1196   522 LAGAVAVLIGVEAAYEAALEAALAAalqnivvedDEVAAAAIEYLKAAkagratflpLDKIRARAALAAALARGAIGAAV 601

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  631 ASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLR----LDYQHEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKE 706
Cdd:COG1196   602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL 681

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  707 DSLEAVKARLDTAEDQHLVEMEEMLSKLQEAEIKVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEgk 786
Cdd:COG1196   682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP-- 759

                         490       500
                  ....*....|....*....|.
gi 672073054  787 LEIETLRQQLEGAEKQIKNLE 807
Cdd:COG1196   760 PDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1773-2074 6.93e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 6.93e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1773 EEVLKEKEKLE------ESYFVLQKEISQLaqtnshisaDLLEAQSENRTLRKDKSKLTLKIRELEtlhsftaaQTAEDA 1846
Cdd:COG1196   196 GELERQLEPLErqaekaERYRELKEELKEL---------EAELLLLKLRELEAELEELEAELEELE--------AELEEL 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1847 MQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQ 1926
Cdd:COG1196   259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1927 LSALQEENVKLAEELGRTRDEVTSHQK----LEEERSVLNNQLLEMKKRESEYRKDADEEKASLQKSISLTSALLTEKDA 2002
Cdd:COG1196   339 LEELEEELEEAEEELEEAEAELAEAEEalleAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672073054 2003 ELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDVQTEEDERAQ 2074
Cdd:COG1196   419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2171-2187 1.59e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.59e-07
                           10
                   ....*....|....*..
gi 672073054  2171 RPYCEICEMFGHWATNC 2187
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
PRK11281 PRK11281
mechanosensitive channel MscK;
1870-2095 2.21e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.99  E-value: 2.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1870 TNAKLQSELDTLKENNLKTVEE------LNKSKELLneenQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELG- 1942
Cdd:PRK11281   37 TEADVQAQLDALNKQKLLEAEDklvqqdLEQTLALL----DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDe 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1943 --RTRDEVTSHQKLEEERSVLNNQLLEMKKRESEYrkdaDEEKASLQKSISLTSALLTEKDAELEKLRNEvtvLRGENAS 2020
Cdd:PRK11281  113 etRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEY----NSQLVSLQTQPERAQAALYANSQRLQQIRNL---LKGGKVG 185

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054 2021 AKSLHSvvqtleSDKVKLELKVKNLELQLKENKRQLsssSGNTDVQTEEderaqESQIDFLNSVIVDLQRKNQDL 2095
Cdd:PRK11281  186 GKALRP------SQRVLLQAEQALLNAQNDLQRKSL---EGNTQLQDLL-----QKQRDYLTARIQRLEHQLQLL 246
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
337-738 9.00e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 9.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  337 ETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHD----------QHVLELE 406
Cdd:PRK02224  241 EVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGlddadaeaveARREELE 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  407 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQIS----EDPENTQTKLEhARIKELEQS 482
Cdd:PRK02224  321 DRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAreavEDRREEIEELE-EEIEELRER 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  483 LLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESSKPP------------GDVDMSLSLLQE 550
Cdd:PRK02224  400 FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPecgqpvegsphvETIEEDRERVEE 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  551 ISALQEKLEVTHTDHQNEVTSLKDHFGTREEMFQKEIKAlHAATEKLSKENESL---RSKLDHANKENSDVIALWKSKLE 627
Cdd:PRK02224  480 LEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERR-EDLEELIAERRETIeekRERAEELRERAAELEAEAEEKRE 558

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  628 TAIASHQQAMEELKVsfskgIGTDSAEFAELKTQIERL---------RLDYQHEIESLQSK------QDSERSAHAKEME 692
Cdd:PRK02224  559 AAAEAEEEAEEAREE-----VAELNSKLAELKERIESLerirtllaaIADAEDEIERLREKrealaeLNDERRERLAEKR 633

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 672073054  693 SMKAKLMKiiKEKEDSLEAVKARLDTAEdQHLVEMEEMLSKLQEAE 738
Cdd:PRK02224  634 ERKRELEA--EFDEARIEEAREDKERAE-EYLEQVEEKLDELREER 676
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1857-2100 4.52e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.90  E-value: 4.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1857 KTETLASLEDTKQTNAKLQ---SELDTLKENNLKTVEELNKSKELLNEENQK--------MEEFKKEIETLKQAAAQKSQ 1925
Cdd:TIGR02168  174 RKETERKLERTRENLDRLEdilNELERQLKSLERQAEKAERYKELKAELRELelallvlrLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1926 QLSALQEENVKLAEELGRTRDEVTS-HQKLEEERSVLNNQLLEMKKRESEYRKdADEEKASLQKSISLTSALLTEKDAEL 2004
Cdd:TIGR02168  254 ELEELTAELQELEEKLEELRLEVSElEEEIEELQKELYALANEISRLEQQKQI-LRERLANLERQLEELEAQLEELESKL 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  2005 EKLRNEVTVLRGENASAKslhSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDvQTEEDERAQESQIDFLNSV 2084
Cdd:TIGR02168  333 DELAEELAELEEKLEELK---EELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIASLNNEIERLEAR 408

                          250
                   ....*....|....*.
gi 672073054  2085 IVDLQRKNQDLKMKVE 2100
Cdd:TIGR02168  409 LERLEDRRERLQQEIE 424
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2131-2148 1.90e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.90e-04
                           10
                   ....*....|....*...
gi 672073054  2131 RLFCDICDCFDlHDTEDC 2148
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
 
Name Accession Description Interval E-value
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 213-277 2.36e-34

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 126.36  E-value: 2.36e-34
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054   213 IGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKV 277
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY pfam01302
CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of ...
 60-124 8.35e-31

CAP-Gly domain; Cytoskeleton-associated proteins (CAPs) are involved in the organization of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 460154 [Multi-domain]  Cd Length: 65  Bit Score: 116.35  E-value: 8.35e-31
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054    60 VGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKL 124
Cdd:pfam01302    1 VGDRVEVPGGRRGTVRYVGPVPFAPGVWVGVELDEPVGKNDGSVKGVRYFECPPKHGVFVRPSKV 65
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 213-278 6.82e-28

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 108.06  E-value: 6.82e-28
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672073054    213 IGDRVLVGGT-KAGVVRFLGETDFAKGEWCGVELDEPL-GKNDGAVAGTRYFQCQPKYGLFAPVHKVT 278
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPLrGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
CAP_GLY smart01052
Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and ...
 60-125 3.53e-27

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network; A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.


Pssm-ID: 214997 [Multi-domain]  Cd Length: 68  Bit Score: 106.13  E-value: 3.53e-27
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672073054     60 VGERVWVNGN-KPGFIQFLGETQFAPGQWAGIVLDEP-IGKNDGSVAGVRYFQCEPLKGIFTRPSKLT 125
Cdd:smart01052    1 VGDRVEVGGGgRRGTVRYVGPTPFAPGVWVGVELDEPlRGKNDGSVKGVRYFECPPKHGIFVRPSKVE 68
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1047-1919 6.25e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.45  E-value: 6.25e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1047 QKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKAKSLTYL--------LTSAKKEIEVMSEELRGLKSEKQLFAQEASA 1118
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELkaelreleLALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1119 LKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQE 1198
Cdd:TIGR02168  258 LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1199 ELlkmhmekdsleaskVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQvkkltaenmvlVKDKDDVIQKLQSAYEELV 1278
Cdd:TIGR02168  338 EL--------------AELEEKLEELKEELESLEAELEELEAELEELESR-----------LEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1279 KDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENllQSNRDLQFEKDTLRQGQEKLSASLEAtlqvkqlLSTEA 1358
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELER-------LEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1359 ETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEeiktcraitdseciqllhEKESLAASERALLAEKEELLNENRVI 1438
Cdd:TIGR02168  464 EELREELEEAEQALDAAERELAQLQARLDSLERLQE------------------NLEGFSEGVKALLKNQSGLSGILGVL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1439 TEKLNKHSEEVTRLEVSLNEKITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKY-- 1516
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVak 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1517 --EQEATNRRLAVQEkvkLLGNI---DALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTsmMQAKEdlnA 1591
Cdd:TIGR02168  606 dlVKFDPKLRKALSY---LLGGVlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSS--ILERR---R 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1592 ELKTCCCEKNILLRDGLNLQEECQKLNEEIREIQQtlmlEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQ 1671
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1672 TENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTER 1751
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1752 AEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIREL 1831
Cdd:TIGR02168  834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1832 ETLHSFTAAQ--TAEDAMQIMEQMTKEKTETLA-------------------SLEDTKQTNAKLQSELDTLKENNLKTVE 1890
Cdd:TIGR02168  914 RRELEELREKlaQLELRLEGLEVRIDNLQERLSeeysltleeaealenkiedDEEEARRRLKRLENKIKELGPVNLAAIE 993

                          890       900
                   ....*....|....*....|....*....
gi 672073054  1891 ELNKSKELLNEENQKMEEFKKEIETLKQA 1919
Cdd:TIGR02168  994 EYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 724-1487 1.42e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 1.42e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   724 LVEMEEMLSKLQE--AEIKvKELEVLQAKySEQTQVVGHLTSQLSVVEEQLLDLDALRKANsegklEIETLRQQLEGAEK 801
Cdd:TIGR02168  181 LERTRENLDRLEDilNELE-RQLKSLERQ-AEKAERYKELKAELRELELALLVLRLEELRE-----ELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   802 QIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLH 881
Cdd:TIGR02168  254 ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   882 QKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQ 961
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   962 LKLTKANENASLLQKSIGEVTLKAEQSQ----QEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKI 1037
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAEleelEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1038 KhEEILQNFQ------KMLVDTEDKLKAAQEANRDLMQDMEELKSQADKA--KSLTYLLT----SAKKEIEVMSEELRG- 1104
Cdd:TIGR02168  494 L-ERLQENLEgfsegvKALLKNQSGLSGILGVLSELISVDEGYEAAIEAAlgGRLQAVVVenlnAAKKAIAFLKQNELGr 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1105 -------LKSEKQLFAQEASALKLEKG--SLLSKLIEVETKITLLQED--QQKLW--SVNENLHLEKERISEEKQVAEKR 1171
Cdd:TIGR02168  573 vtflpldSIKGTEIQGNDREILKNIEGflGVAKDLVKFDPKLRKALSYllGGVLVvdDLDNALELAKKLRPGYRIVTLDG 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1172 YQ--------QEHRDKESLVVER----EKLLKEINVTQEELLKMHMEKDSLEASKVSMQVLIEELRFCKDKLMAMSEKAR 1239
Cdd:TIGR02168  653 DLvrpggvitGGSAKTNSSILERrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALR 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1240 AEKEQLEGQVKKLTAEnmvlvkdkddvIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENL 1319
Cdd:TIGR02168  733 KDLARLEAEVEQLEER-----------IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1320 LQSNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIKTC 1399
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1400 RAITDSECIQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRLEVSLNEKITYLTSEKEMACQKVARLKK 1479
Cdd:TIGR02168  882 RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALEN 961


                   ....*...
gi 672073054  1480 QQDSLLKE 1487
Cdd:TIGR02168  962 KIEDDEEE 969
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 728-1623 3.26e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 3.26e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   728 EEMLSKLQEAEIKVKELEVLQAKYSEQtqvVGHLTSQLSVVEEqlldldALRKANSEGKLEIETLRQQLEGAEKQIKNLE 807
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQ---LKSLERQAEKAER------YKELKAELRELELALLVLRLEELREELEELQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   808 MERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQF 887
Cdd:TIGR02168  246 EELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   888 NMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKA 967
Cdd:TIGR02168  326 EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERL 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   968 NENASLLQKSIGEvtLKAEQSQQEaakkheeekkelenkllelekkmetshyqcQDLKAKYEKASSETKIKHEEILQNFQ 1047
Cdd:TIGR02168  406 EARLERLEDRRER--LQQEIEELL------------------------------KKLEEAELKELQAELEELEEELEELQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1048 KMLVDTEDKLKAAQEANRDLMQDMEELKSQADKAKSLTYLLtsakkeiEVMSEELRGLKSEKQLFAQEASALKLEKGsLL 1127
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-------ERLQENLEGFSEGVKALLKNQSGLSGILG-VL 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1128 SKLIEVETKI-----TLLQEDQQKLWSVNENL------HLEKERISE------------EKQVAEKRYQQEHRDKESLVV 1184
Cdd:TIGR02168  526 SELISVDEGYeaaieAALGGRLQAVVVENLNAakkaiaFLKQNELGRvtflpldsikgtEIQGNDREILKNIEGFLGVAK 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1185 EREKLLKEINVTQEELL-KMHMEKDSLEASKVSMQVLIEELRFCKD----------------KLMAMSEKaRAEKEQLEG 1247
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLgGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvrpggvitggsakTNSSILER-RREIEELEE 684

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1248 QVKKLTAEnmvlVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQ 1327
Cdd:TIGR02168  685 KIEELEEK----IAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1328 FEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRAITDSEC 1407
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1408 IQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRLEVSLnekityltsekemacqkvARLKKQQDSLLKE 1487
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL------------------ALLRSELEELSEE 902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1488 KSALEVQNGDLLADRESSIKAIGDLKRKyEQEATNRRLAVQEKVKLLGNIDAlkkELQQRKKENQELASSKCDLSlmLKE 1567
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELR-LEGLEVRIDNLQERLSEEYSLTL---EEAEALENKIEDDEEEARRR--LKR 976

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 672073054  1568 AQTAKKNLEKEHTSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEECQKLNEEIRE 1623
Cdd:TIGR02168  977 LENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARE 1032
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 634-1349 4.55e-17

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 88.20  E-value: 4.55e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   634 QQAMEELKVsFSKGIGTDSAEFAELKTQIERLRLDYQHEIES---LQSKQDSERSAHAKEMESMKAKLMKIIKEKeDSLE 710
Cdd:TIGR02169  173 EKALEELEE-VEENIERLDLIIDEKRQQLERLRREREKAERYqalLKEKREYEGYELLKEKEALERQKEAIERQL-ASLE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   711 AVKARLDTAEDQHLVEMEEMLSKLQEAEIKVKELEvlQAKYSEQTQVVGHLTSQLSVVEEQlldldalrkansegkleIE 790
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG--EEEQLRVKEKIGELEAEIASLERS-----------------IA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   791 TLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQ 870
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   871 TSMQDTVNKLH-------QKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQL 943
Cdd:TIGR02169  392 EKLEKLKREINelkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   944 TKMNDELRLKERSVEELQLKLTKANENAS--------------LLQKSI-GEVTLKAEQSQQEAAKKHEEEKKELENKLL 1008
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARaseervrggraveeVLKASIqGVHGTVAQLGSVGERYATAIEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1009 ELEKKMETSHYQCQDLKA------------KYEKASSETKIKHEEILQNFQKMLVDTEDKLKAA-QEANRD--LMQDMEE 1073
Cdd:TIGR02169  552 VVVEDDAVAKEAIELLKRrkagratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAfKYVFGDtlVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1074 LKSQ-----------------------ADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKL 1130
Cdd:TIGR02169  632 ARRLmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQEL 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1131 IEVETKITLLQEDQQKLwsvNENLHLEKERIsEEKQVAEKRYQQEHRDKESlvvEREKLLKEINVTQEELLKMHMEKDSL 1210
Cdd:TIGR02169  712 SDASRKIGEIEKEIEQL---EQEEEKLKERL-EELEEDLSSLEQEIENVKS---ELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1211 EASKVSMQvlIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLvkdkDDVIQKLQSAYEELVKDQKALVQEIED 1290
Cdd:TIGR02169  785 EARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL----EKEIQELQEQRIDLKEQIKSIEKEIEN 858

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 672073054  1291 LTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLS--------------ASLEATLQ 1349
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEaqiekkrkrlselkAKLEALEE 931
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 352-992 3.00e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 3.00e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   352 LQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDqhvlELEAKMDQLRTMVEAADREKVELLNQLE 431
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSKVA 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   432 EEKRKVEDLQFRVEEESITKGDLE-QKSQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSR 510
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEdRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREE 469

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   511 IMELEKDLALRVQEVAELRRRLES----------------------SKPPGDVDMSLSLLQEISALQEKLEVTHTDHQNE 568
Cdd:TIGR02168  470 LEEAEQALDAAERELAQLQARLDSlerlqenlegfsegvkallknqSGLSGILGVLSELISVDEGYEAAIEAALGGRLQA 549

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   569 VTSLKDHFGTREEMFQKEIKALHAATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELkvsFSKGI 648
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYL---LGGVL 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   649 GTDSaefaeLKTQIERLR-LDYQHEIESLQ----------SKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLD 717
Cdd:TIGR02168  627 VVDD-----LDNALELAKkLRPGYRIVTLDgdlvrpggviTGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALA 701

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   718 TAEDQhLVEMEEMLSKLQEAEI-KVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDAlrkansegklEIETLRQQL 796
Cdd:TIGR02168  702 ELRKE-LEELEEELEQLRKELEeLSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA----------EIEELEERL 770

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   797 EGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQvketlekELQTLKEKFASASEEAVSTQTSMQDT 876
Cdd:TIGR02168  771 EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNE-------EAANLRERLESLERRIAATERRLEDL 843

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   877 VNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERS 956
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 672073054   957 VEELQLKLTKA-----------NENASLLQKSIGEVTLKAEQSQQEA 992
Cdd:TIGR02168  924 LAQLELRLEGLevridnlqerlSEEYSLTLEEAEALENKIEDDEEEA 970
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 656-1297 7.62e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.75  E-value: 7.62e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  656 AELKTQIERLR------LDYQHEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEdqhlVEMEE 729
Cdd:COG1196   196 GELERQLEPLErqaekaERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELE----AELEE 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  730 MLSKLQEAEikvKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEgklEIETLRQQLEGAEKQIKNLEME 809
Cdd:COG1196   272 LRLELEELE---LELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEE---ELAELEEELEELEEELEELEEE 345

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  810 RNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNM 889
Cdd:COG1196   346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  890 LSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEImkmsGDNSSQLTKMNDELRLKERSVEELQLKLTKANE 969
Cdd:COG1196   426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL----LEEAALLEAALAELLEELAEAAARLLLLLEAEA 501

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  970 NASLLQKSIGEVTLKAEQSQQEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEilQNFQKM 1049
Cdd:COG1196   502 DYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGR--ATFLPL 579

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1050 LVDTEDKLKAAQEANRDLMQDMEELKSQADKAKSLTYLL--TSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLL 1127
Cdd:COG1196   580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLgdTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG 659

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1128 SKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKMHMEK 1207
Cdd:COG1196   660 GSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE 739

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1208 DSLEASKVSMQVLIEELRFCKDklmamSEKARAEKEQLEGQVKKLTAENMvlvkdkdDVIQklqsAYEELVKDQKALVQE 1287
Cdd:COG1196   740 ELLEEEELLEEEALEELPEPPD-----LEELERELERLEREIEALGPVNL-------LAIE----EYEELEERYDFLSEQ 803

                         650
                  ....*....|
gi 672073054 1288 IEDLTTEKKS 1297
Cdd:COG1196   804 REDLEEARET 813
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1159-1917 1.48e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 80.11  E-value: 1.48e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1159 ERISEEKQVAEkRYQQEHRDKESlvVEREKLLKEINVTQEELLKMHMEKDSLEASKVSMQVLIEELRfckdklmAMSEKA 1238
Cdd:TIGR02169  201 ERLRREREKAE-RYQALLKEKRE--YEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELE-------KRLEEI 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1239 RAEKEQLEGQVKKLTAENMVLVKDKddvIQKLQSAYEELVKDQKALVQEIEDlttekksAAEKQMNLDNTCLTLKAEREN 1318
Cdd:TIGR02169  271 EQLLEELNKKIKDLGEEEQLRVKEK---IGELEAEIASLERSIAEKERELED-------AEERLAKLEAEIDKLLAEIEE 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1319 LLQSNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIkt 1398
Cdd:TIGR02169  341 LEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRL-- 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1399 craitDSECIQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRLEVS---LNEKITYLTSEKEMACQKVA 1475
Cdd:TIGR02169  419 -----SEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQElydLKEEYDRVEKELSKLQRELA 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1476 RLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKvklLGNI----DALKKELQQRKKEN 1551
Cdd:TIGR02169  494 EAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNR---LNNVvvedDAVAKEAIELLKRR 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1552 Q----------ELASSKCDLSLMLKEAQTAKK----NLEKEHTSM-------------MQAKEDLNAELKTCCCEKNILL 1604
Cdd:TIGR02169  571 KagratflplnKMRDERRDLSILSEDGVIGFAvdlvEFDPKYEPAfkyvfgdtlvvedIEAARRLMGKYRMVTLEGELFE 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1605 RDGL----------------NLQEECQKLNEEIREIQ---QTLMLEK---EARAKESESSLYESNKLHGRI----VLLEE 1658
Cdd:TIGR02169  651 KSGAmtggsraprggilfsrSEPAELQRLRERLEGLKrelSSLQSELrriENRLDELSQELSDASRKIGEIekeiEQLEQ 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1659 EIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLK-----SDFAALSKSKLELQELHSCL 1733
Cdd:TIGR02169  731 EEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEarlshSRIPEIQAELSKLEEEVSRI 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1734 TKILDDLR-------LNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISAD 1806
Cdd:TIGR02169  811 EARLREIEqklnrltLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKE 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1807 LLEAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIME-----QMTKEKTETLASLEDTKQTNAKLQSELDTL 1881
Cdd:TIGR02169  891 RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEiedpkGEDEEIPEEELSLEDVQAELQRVEEEIRAL 970

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 672073054  1882 KENNLKTVEELNKSKELLNEENQKMEEFKKEIETLK 1917
Cdd:TIGR02169  971 EPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1288-1919 3.41e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 3.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1288 IEDLTTEKksaaEKQMNldntclTLKAERENLLQSnRDLQFEKDTLRQgqEKLSASLEATLQVKQLLSTEAETLRTQLDC 1367
Cdd:COG1196   191 LEDILGEL----ERQLE------PLERQAEKAERY-RELKEELKELEA--ELLLLKLRELEAELEELEAELEELEAELEE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1368 ATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSE 1447
Cdd:COG1196   258 LEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1448 EVTRLEvslnekityltsekemacQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAV 1527
Cdd:COG1196   338 ELEELE------------------EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA 399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1528 QEKVKLLGNIDALKKELQQRKKENQELASSkcdlslmLKEAQTAKKNLEKEHTSMMQAKEDLNAELKtcccEKNILLRDG 1607
Cdd:COG1196   400 AQLEELEEAEEALLERLERLEEELEELEEA-------LAELEEEEEEEEEALEEAAEEEAELEEEEE----ALLELLAEL 468

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1608 LNLQEECQKLNEEIREIQQTLmLEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQK 1687
Cdd:COG1196   469 LEEAALLEAALAELLEELAEA-AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAA 547

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1688 VVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKRE 1767
Cdd:COG1196   548 LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1768 MMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAM 1847
Cdd:COG1196   628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672073054 1848 QIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELnkskELLNEENQKMEEFKKEIETLKQA 1919
Cdd:COG1196   708 ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA----LEELPEPPDLEELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 652-1291 1.76e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 76.63  E-value: 1.76e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   652 SAEFAELKTQIERLRLdYQHEIESLQSKQDSERSAHAKEMESMKAKLMkIIKEKEDSLEAVKARLDTAEDQHLVEMEEML 731
Cdd:TIGR02168  259 TAELQELEEKLEELRL-EVSELEEEIEELQKELYALANEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELA 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   732 SKLQEAEIKVKELEV----LQAKYSEQTQVVGHLTSQLSVVEEQLldlDALRKANSEGKLEIETLRQQLEGAEKQIKNLE 807
Cdd:TIGR02168  337 EELAELEEKLEELKEelesLEAELEELEAELEELESRLEELEEQL---ETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   808 MERNAESSKANSITKDLQGKELMLtsLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQF 887
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARL 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   888 NMLSSELEKLRENLTDMEAKFKEKDERED------QLVKAKEK----LENDIAEIMKMSGDNSSQLTKMNDELRLKERSV 957
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGilgvlsELISVDEGyeaaIEAALGGRLQAVVVENLNAAKKAIAFLKQNELG 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   958 EELQLKLTKANENAslLQKSIGEVTLKAEQSQQEAAKKHEEEKKELENKLLE-LEKKMETSHYQCQDLKAKYEKASS--- 1033
Cdd:TIGR02168  572 RVTFLPLDSIKGTE--IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlGGVLVVDDLDNALELAKKLRPGYRivt 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1034 ------------------------ETKIKHEEILQNFQKMLVDTEDKLKAAQEAnRDLMQDMEELKSQADKAK------- 1082
Cdd:TIGR02168  650 ldgdlvrpggvitggsaktnssilERRREIEELEEKIEELEEKIAELEKALAEL-RKELEELEEELEQLRKELeelsrqi 728

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1083 -SLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKLwsvNENLHLEKERI 1161
Cdd:TIGR02168  729 sALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL---KEELKALREAL 805

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1162 SEekqvAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKMHMEKDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAE 1241
Cdd:TIGR02168  806 DE----LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNE 881

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 672073054  1242 KEQLEGQVKKLTAENMVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDL 1291
Cdd:TIGR02168  882 RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1053-1663 2.67e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 75.74  E-value: 2.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1053 TEDKLKAAQEaN----RDLMQD----MEELKSQADKAKS-LTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEK 1123
Cdd:COG1196   177 AERKLEATEE-NlerlEDILGElerqLEPLERQAEKAERyRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1124 GSLLSKLIEVETKITLLQEDQQKlwsvnenLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKM 1203
Cdd:COG1196   256 EELEAELAELEAELEELRLELEE-------LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL 328

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1204 HMEKDSLEASKVSMQVLIEELrfckDKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKDDVIQKLQSAYEELVKDQKA 1283
Cdd:COG1196   329 EEELEELEEELEELEEELEEA----EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1284 LVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRT 1363
Cdd:COG1196   405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1364 QLDcATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERALLAEKEELLNEN-----RVI 1438
Cdd:COG1196   485 ELA-EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDdevaaAAI 563

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1439 TEKLNKHSEEVTRLEvsLNEKITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADResSIKAIGDLKRKYEQ 1518
Cdd:COG1196   564 EYLKAAKAGRATFLP--LDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR--TLVAARLEAALRRA 639

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1519 EATNRRLAVQEKVKLLGNIDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELktccc 1598
Cdd:COG1196   640 VTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE----- 714

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054 1599 EKNILLRDGLNLQEECQKLNEEIREIQQTLMLEKEARAKESESSLYESNKLHGRIVLLEEEIQGL 1663
Cdd:COG1196   715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 405-1194 3.39e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.48  E-value: 3.39e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   405 LEAKMDQLRTMVEAA------DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHARIKE 478
Cdd:TIGR02168  150 IEAKPEERRAIFEEAagiskyKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELAL 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   479 LEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKL 558
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQ-----KELYALANEISRLEQQK 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   559 EVTHTDHQNEVTSLKDHFGTREEMFQKEIKALhAATEKLSKENESLRSKLDHANKENSDVIALWKSkLETAIASHQQAME 638
Cdd:TIGR02168  305 QILRERLANLERQLEELEAQLEELESKLDELA-EELAELEEKLEELKEELESLEAELEELEAELEE-LESRLEELEEQLE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   639 ELK---VSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKAR 715
Cdd:TIGR02168  383 TLRskvAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEA 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   716 LDTAEDQHLVEMEEMLS---KLQEAEIKVKELEVLQAKYSEQTQ--------------VVGHLTSQLSVVEEQLLDLDA- 777
Cdd:TIGR02168  463 LEELREELEEAEQALDAaerELAQLQARLDSLERLQENLEGFSEgvkallknqsglsgILGVLSELISVDEGYEAAIEAa 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   778 --------LRKANSEGKLEIETLRQQLEG----------AEKQIKNLEMERNAESSKANSITKDLQ-------------- 825
Cdd:TIGR02168  543 lggrlqavVVENLNAAKKAIAFLKQNELGrvtflpldsiKGTEIQGNDREILKNIEGFLGVAKDLVkfdpklrkalsyll 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   826 GKELMLTSLQSNLNEVNQVKE-----TLEKELQT----LKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEK 896
Cdd:TIGR02168  623 GGVLVVDDLDNALELAKKLRPgyrivTLDGDLVRpggvITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   897 LRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASLLQK 976
Cdd:TIGR02168  703 LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   977 SIGEVTLKAEQSQQEAAKKHEEEKKELEnkllelekkmetshyQCQDLKAKYEKAsSETKIKHEEILQNFQKMLVDTEDK 1056
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRA---------------ELTLLNEEAANL-RERLESLERRIAATERRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1057 LKAAQEANRDLMQDMEELKSQADKAKSltyLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKLIEVETK 1136
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELES---ELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 672073054  1137 ITLLQEDQQKLWSVNENLhleKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEIN 1194
Cdd:TIGR02168  924 LAQLELRLEGLEVRIDNL---QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLE 978
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1412-2077 6.29e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.71  E-value: 6.29e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1412 HEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTR---LEVSLNE-KITYLTSEKEMACQKVARLKKQQDSLLKE 1487
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERykeLKAELRElELALLVLRLEELREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1488 KSALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKENQELASSKCDLSLMLKE 1567
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1568 AQTAKKNLEKEHTSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEECQKLNEEIREIQQTL------------------- 1628
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIaslnneierlearlerled 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1629 ---MLEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQL 1705
Cdd:TIGR02168  415 rreRLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1706 AA---NIETLKSDFAALSKSKLELQELHSCLTKILD---DLRLNHEVAVTERAEvlqdnkNLLAEKREMMLRNEEVLKEK 1779
Cdd:TIGR02168  495 ERlqeNLEGFSEGVKALLKNQSGLSGILGVLSELISvdeGYEAAIEAALGGRLQ------AVVVENLNAAKKAIAFLKQN 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1780 EKLEESYFVLQKEISQLAQTNshiSADLLEAQSENRTLRKDKSKLTLKIRE-LETLHSFTA-AQTAEDAMQIMEQMTKEk 1857
Cdd:TIGR02168  569 ELGRVTFLPLDSIKGTEIQGN---DREILKNIEGFLGVAKDLVKFDPKLRKaLSYLLGGVLvVDDLDNALELAKKLRPG- 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1858 tETLASLEDTKQTNAKLQSELDTLKENNLktveeLNKSKELLNEEnQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKL 1937
Cdd:TIGR02168  645 -YRIVTLDGDLVRPGGVITGGSAKTNSSI-----LERRREIEELE-EKIEELEEKIAELEKALAELRKELEELEEELEQL 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1938 AEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEYRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGE 2017
Cdd:TIGR02168  718 RKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE 797

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672073054  2018 NASAK----SLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDVQTEEDERAQESQ 2077
Cdd:TIGR02168  798 LKALRealdELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 351-1046 1.34e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 1.34e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALArdghDQHVLELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:TIGR02168  257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL----EQQKQILRERLANLERQLEELEAQLEELESKL 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   431 EEEKRKVEDLQFRVEEesiTKGDLEQKSQISEDPENTQTKLEhARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSR 510
Cdd:TIGR02168  333 DELAEELAELEEKLEE---LKEELESLEAELEELEAELEELE-SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEAR 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   511 IMELEKDLALRVQEVAELRRRLESSkppgDVDMSLSLLQEISALQEKLEVTHTDHQNEVTSLKDHFGTREEMFQK----- 585
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEEA----ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAaerel 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   586 -----EIKALHAATEKLSKENESLRSKLDHANKENSDVIAL---------WKSKLETAIASHQQAME-------ELKVSF 644
Cdd:TIGR02168  485 aqlqaRLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLselisvdegYEAAIEAALGGRLQAVVvenlnaaKKAIAF 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   645 SKGIGTDSAEFAELKTQIERlRLDYQHEiESLQSKQDSERSAhakemesmkAKLMKIIKEKEDSLEAVKARLDTAEDqhL 724
Cdd:TIGR02168  565 LKQNELGRVTFLPLDSIKGT-EIQGNDR-EILKNIEGFLGVA---------KDLVKFDPKLRKALSYLLGGVLVVDD--L 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   725 VEMEEMLSKLQEAE-IKVKELEVLQAKYSeqtqVVGHLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEGAEKQI 803
Cdd:TIGR02168  632 DNALELAKKLRPGYrIVTLDGDLVRPGGV----ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   804 KNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQK 883
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   884 EEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLK 963
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   964 LTKANENASLLQKSIGEVtlkaeQSQQEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEIL 1043
Cdd:TIGR02168  868 IEELESELEALLNERASL-----EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ 942


                   ...
gi 672073054  1044 QNF 1046
Cdd:TIGR02168  943 ERL 945
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 351-932 3.00e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 3.00e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQH----------VLELEAKMDQLRTMVEAAD 420
Cdd:COG1196   236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAqaeeyellaeLARLEQDIARLEERRRELE 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  421 REKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEdpentqtklehARIKELEQSLLFEKTKADKLQRELEDT 500
Cdd:COG1196   316 ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE-----------AELAEAEEALLEAEAELAEAEEELEEL 384

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  501 RVATVSEKSRIMELEKDLALRVQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEVTHTDHQNEVTSLKDHFGTRE 580
Cdd:COG1196   385 AEELLEALRAAAELAAQLEELEEAEEALLERLERLE-----EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  581 EMFQKEIKALHAATEKLSKENESLRSKLDHANKENSDVIALWKSKLE---TAIASHQQAMEELKVSFSKGIGTDSAEFAE 657
Cdd:COG1196   460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFlegVKAALLLAGLRGLAGAVAVLIGVEAAYEAA 539

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  658 LKTQIERLRLDYQHEIESLQSKQD----SERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEDQHLVEMEEMLSK 733
Cdd:COG1196   540 LEAALAAALQNIVVEDDEVAAAAIeylkAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  734 LQEAEIKVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNAE 813
Cdd:COG1196   620 DTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEAL 699

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  814 SSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDT------VNKLHQKEEQF 887
Cdd:COG1196   700 LAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLeelereLERLEREIEAL 779

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 672073054  888 ---NMLS-SELEKLRENLTDMEAkfkekdEREDqLVKAKEKLENDIAEI 932
Cdd:COG1196   780 gpvNLLAiEEYEELEERYDFLSE------QRED-LEEARETLEEAIEEI 821
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 356-1194 3.32e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 72.40  E-value: 3.32e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   356 LKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHdqhvLELEAKMDQLRTMVEAADREKVELLNQLEEEKR 435
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEV----SELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   436 KVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKlEHARIKELEQSLLFEKTKADKLQRELE----DTRVATVSEKSRI 511
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAELEE-KLEELKEELESLEAELEELEAELEELEsrleELEEQLETLRSKV 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   512 MELEKDLALRVQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEvthtdhQNEVTSLKDHFGTREEMFQKEIKALH 591
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLE-----DRRERLQQEIEELLKKLE------EAELKELQAELEELEEELEELQEELE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   592 AATEKLSKENESLRSKLDHANKENSDVIALwKSKLETAiashqQAMEELKVSFSKGIgtdsaefAELKTQIERLRLDYQH 671
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQL-QARLDSL-----ERLQENLEGFSEGV-------KALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   672 EIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVK---------ARLDTAEDQHL-VEMEEMLSKLQEAEIKV 741
Cdd:TIGR02168  525 LSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKqnelgrvtfLPLDSIKGTEIqGNDREILKNIEGFLGVA 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   742 KELEVLQAKYSeqtQVVGHLTSQLSVVEeqllDLD-ALRKANSEG---------------------------------KL 787
Cdd:TIGR02168  605 KDLVKFDPKLR---KALSYLLGGVLVVD----DLDnALELAKKLRpgyrivtldgdlvrpggvitggsaktnssilerRR 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   788 EIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEav 867
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-- 755

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   868 stqtsmqdtvnkLHQKEEQFNMLSSELEKLREnltdmeakfkEKDEREDQLVKAKEKLENDIAEImkmsGDNSSQLTKMN 947
Cdd:TIGR02168  756 ------------LTELEAEIEELEERLEEAEE----------ELAEAEAEIEELEAQIEQLKEEL----KALREALDELR 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   948 DELRLKERSVEELQLKLTKANENASLLQKSIGEVTLKAEQSQQEAAkkheeekkelenkllELEKKMETSHYQCQDLKAK 1027
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIE---------------SLAAEIEELEELIEELESE 874

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1028 YEKASSEtKIKHEEILQNFQKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKAKsltylltSAKKEIEVMSEELRG-LK 1106
Cdd:TIGR02168  875 LEALLNE-RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE-------LRLEGLEVRIDNLQErLS 946

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1107 SEKQLFAQEASALKLEKGSLLSKLievETKITLLQEDQQKLWSVNENlhlekeRISEEKQVAEkRYQQEHRDKESLVVER 1186
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIKELGPVNLA------AIEEYEELKE-RYDFLTAQKEDLTEAK 1016


                   ....*...
gi 672073054  1187 EKLLKEIN 1194
Cdd:TIGR02168 1017 ETLEEAIE 1024
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 211-271 5.67e-12

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 71.25  E-value: 5.67e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672073054  211 LKIGDRVLVGGTKaGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLF 271
Cdd:COG5244     4 LSVNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIF 63
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1410-2057 6.38e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.25  E-value: 6.38e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1410 LLHEKESLAASERAL---LAEKEELLNENRVITEKLNKHSEEVTRLEVSLNEKITYLTSEKEMACQK------------- 1473
Cdd:TIGR02169  228 LLKEKEALERQKEAIerqLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEkigeleaeiasle 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1474 ----------------VARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKY-------EQEATNRRLAVQEK 1530
Cdd:TIGR02169  308 rsiaekereledaeerLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELedlraelEEVDKEFAETRDEL 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1531 VKLLGNIDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELKTCCCEKNILLRDG--- 1607
Cdd:TIGR02169  388 KDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLsky 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1608 ----LNLQEECQKLNEEIREIQQTL-MLEKEARAKESESSLYESNKLhgrivLLEEEIQG-LRTCSEQLQTENFTLTQEK 1681
Cdd:TIGR02169  468 eqelYDLKEEYDRVEKELSKLQRELaEAEAQARASEERVRGGRAVEE-----VLKASIQGvHGTVAQLGSVGERYATAIE 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1682 TNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLN-------HEVAVterAEV 1754
Cdd:TIGR02169  543 VAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDlvefdpkYEPAF---KYV 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1755 LQDNK--NLLAEKREMMLRNEEVLKEKEKLEES------YFVLQKEISQLAQTnshiSADLLEAQSENRTLRKDKSKLTL 1826
Cdd:TIGR02169  620 FGDTLvvEDIEAARRLMGKYRMVTLEGELFEKSgamtggSRAPRGGILFSRSE----PAELQRLRERLEGLKRELSSLQS 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1827 KIRELETlHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELNKSKELLNEENQKM 1906
Cdd:TIGR02169  696 ELRRIEN-RLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDL 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1907 EEFKKEIETLKQAAAQksQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEYRKDADEEKASL 1986
Cdd:TIGR02169  775 HKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSI 852

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672073054  1987 QKSISLTSALLTEKDAELEKLRNEVTVLRGEnasAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLS 2057
Cdd:TIGR02169  853 EKEIENLNGKKEELEEELEELEAALRDLESR---LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS 920
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1727-2025 9.02e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.74  E-value: 9.02e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1727 QELHSCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVL-KEKEKLEESYFVLQKEISQLAQTNSHISA 1805
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELeAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1806 DLLEAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQImEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENN 1885
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL-EELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1886 LKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQL 1965
Cdd:COG1196   375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1966 LEMKKRESEYRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENASAKSLH 2025
Cdd:COG1196   455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1536-2112 1.12e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 70.48  E-value: 1.12e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1536 NIDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELKTCCCEKNILLRdglnLQEECQ 1615
Cdd:PRK03918  166 NLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE----LKEEIE 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1616 KLNEEIREIQQTlMLEKEARAKESESSLYESNKlhgRIVLLEEEIQGLRTCsEQLQTENFTLTQEKTNSEQKVVEIIKEK 1695
Cdd:PRK03918  242 ELEKELESLEGS-KRKLEEKIRELEERIEELKK---EIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDELREIEKRL 316

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1696 ELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLnhevavTERAEVLQDNKNLLaEKREMMLRNEEV 1775
Cdd:PRK03918  317 SRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHEL------YEEAKAKKEELERL-KKRLTGLTPEKL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1776 LKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLH--SFTAAQTAEdamqiMEQM 1853
Cdd:PRK03918  390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHrkELLEEYTAE-----LKRI 464

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1854 TKEKTETLASLEDTKQTNAKLQSELDTLKE--NNLKTVEELNKSKELLNEEN-QKMEEFKKEIETLKQAAAQKSQQLSAL 1930
Cdd:PRK03918  465 EKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSL 544

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1931 QEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLE------------MKKRESEYR-----KDADEEKASLQKSISLT 1993
Cdd:PRK03918  545 KKELEKLEELKKKLAELEKKLDELEEELAELLKELEElgfesveeleerLKELEPFYNeylelKDAEKELEREEKELKKL 624

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1994 SALLTEKDAELEKLRNEVTVLRGENASAKSLHSV--VQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDVQTEEDE 2071
Cdd:PRK03918  625 EEELDKAFEELAETEKRLEELRKELEELEKKYSEeeYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|...
gi 672073054 2072 RAQES--QIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGE 2112
Cdd:PRK03918  705 EREKAkkELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 659-1364 1.53e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 70.15  E-value: 1.53e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   659 KTQIERLRLDYQHEIESLQSKQDSERSAHAKEMESMKAKLMKI------IKEKEDSLEAVKARLDTAEDQHLVEMEEMLS 732
Cdd:pfam15921   73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLqtklqeMQMERDAMADIRRRESQSQEDLRNQLQNTVH 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   733 KLQEAeiKVKELEVLQAKYSEQTQVVGHLTSQLSVVEE---QLLDLDAL--RKANSEGKLEIETLRQQLEGAEKQIKNLE 807
Cdd:pfam15921  153 ELEAA--KCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEirsILVDFEEAsgKKIYEHDSMSTMHFRSLGSAISKILRELD 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   808 MERNAESSKANSITKDL-----QGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSM----QDTVN 878
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLealksESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLeiiqEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   879 KLHQKEEQFNMLSSELEKLRENLTDMEAKFKEK-DEREDQLVKAKEKLENDIAE---IMKMSGDNSSQLTKMNDELRLKE 954
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRSELREAKRMYEDKiEELEKQLVLANSELTEARTErdqFSQESGNLDDQLQKLLADLHKRE 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   955 RsveelQLKLTKaNENASLLQKSIGEvTLKAEQSQQEaakkheeeKKELENKLLELEKKMETSHYQCQDlKAKYEKASSE 1034
Cdd:pfam15921  391 K-----ELSLEK-EQNKRLWDRDTGN-SITIDHLRRE--------LDDRNMEVQRLEALLKAMKSECQG-QMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1035 TKIKHEEILQNFQKMLVDTEDKLKAAQEanrDLMQDMEELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQ 1114
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEMLRKVVE---ELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1115 EASALKLEKGSLLSKLIEVET-KITLLQEDQQklwsvnenLHLEKERISEEKQVAekryQQEHRDKESLVVEREKLLKEI 1193
Cdd:pfam15921  532 ELQHLKNEGDHLRNVQTECEAlKLQMAEKDKV--------IEILRQQIENMTQLV----GQHGRTAGAMQVEKAQLEKEI 599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1194 NVTQEELLKMHMEKDSLEASKVSMQVLIEELRFCKDKLM-AMSEKARA------EKEQLEGQVK-------KLTAENMVL 1259
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVnAGSERLRAvkdikqERDQLLNEVKtsrnelnSLSEDYEVL 679

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1260 VKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKS-------AAEKQMNLDNTcLTLKAERENLLQSNrdLQF---- 1328
Cdd:pfam15921  680 KRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSmegsdghAMKVAMGMQKQ-ITAKRGQIDALQSK--IQFleea 756

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 672073054  1329 ------EKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQ 1364
Cdd:pfam15921  757 mtnankEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQ 798
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 788-1304 2.95e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 68.89  E-value: 2.95e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   788 EIETLRQQLEGAEKQIKNLEMERNA---ESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASE 864
Cdd:TIGR04523  153 ELEKLNNKYNDLKKQKEELENELNLlekEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKD 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   865 EAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQlt 944
Cdd:TIGR04523  233 NIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK-- 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   945 KMNDELRLKERSVEELQLKLTKANENASLLQKSIGEvtLKAE--------QSQQEAAKKHEEEKKELENKLLELEKKMET 1016
Cdd:TIGR04523  311 ELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ--LKKEltnsesenSEKQRELEEKQNEIEKLKKENQSYKQEIKN 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1017 SHYQCQDLKAKYEKASSETKIKHEEI--LQNFQKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKA-KSLTYLLTSAKK 1093
Cdd:TIGR04523  389 LESQINDLESKIQNQEKLNQQKDEQIkkLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIiKNLDNTRESLET 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1094 EIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEKRYq 1173
Cdd:TIGR04523  469 QLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDEL- 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1174 qehrDKESLVVEREKLLKEINVTQEELLKMHMEKDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLT 1253
Cdd:TIGR04523  548 ----NKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAK 623

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|.
gi 672073054  1254 AENmvlvKDKDDVIQKLQSAYEELVKDQKAlVQEIEDLTTEKKSAAEKQMN 1304
Cdd:TIGR04523  624 KEN----EKLSSIIKNIKSKKNKLKQEVKQ-IKETIKEIRNKWPEIIKKIK 669
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1071-1918 3.05e-11

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 69.23  E-value: 3.05e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1071 MEELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKLWSV 1150
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1151 NENLHLEKERISEEKQVAEKRYQQEHR--------DKESLVVEREKLLKEINVTQEELLKMHMEKDSLEASKVSMQVLIE 1222
Cdd:pfam02463  259 EIEKEEEKLAQVLKENKEEEKEKKLQEeelkllakEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1223 ELRFCKDKLMAMSEKARAEKEQLEGQVKKltaenmvLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQ 1302
Cdd:pfam02463  339 ELEKELKELEIKREAEEEEEEELEKLQEK-------LEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1303 MNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLSA---SLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDM 1379
Cdd:pfam02463  412 ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEeleKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLS 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1380 RQLQTSNTSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRLEVSLNEK 1459
Cdd:pfam02463  492 RQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALT 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1460 ITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKL--LGNI 1537
Cdd:pfam02463  572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKEsgLRKG 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1538 DALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEH---TSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEEC 1614
Cdd:pfam02463  652 VSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEilrRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQ 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1615 QKLNEEIREIQQTLMLEKEARAKESESSLYESNKLHGRIVLLEEEIqglrtcSEQLQTENFTLTQEKTNSEQKVVEIIKE 1694
Cdd:pfam02463  732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA------EEREKTEKLKVEEEKEEKLKAQEEELRA 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1695 KELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQdNKNLLAEKREMMLRNEE 1774
Cdd:pfam02463  806 LEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEE-LLQELLLKEEELEEQKL 884

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1775 VLKEKEKLEEsyfvlQKEISQLAQTNSHISADLLEAQSENRTLRKDK-SKLTLKIRELETLHSFTAAQTAEDAMQIMEQM 1853
Cdd:pfam02463  885 KDELESKEEK-----EKEEKKELEEESQKLNLLEEKENEIEERIKEEaEILLKYEEEPEELLLEEADEKEKEENNKEEEE 959

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054  1854 TKEKTETLASLEDTKQtnaklqsELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQ 1918
Cdd:pfam02463  960 ERNKRLLLAKEELGKV-------NLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
340-934 4.09e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.55  E-value: 4.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  340 SRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELaLARDGHDQHVLELEAKMDQLRTMVEAA 419
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  420 DREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLehariKELEQSLLFEKTKADKLQRELED 499
Cdd:PRK03918  258 EEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL-----REIEKRLSRLEEEINGIEERIKE 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  500 TRvatvSEKSRIMELEKdlalrvqEVAELRRRLESSKPpgdvdmSLSLLQEISALQEKLEvthtdhqnevtSLKDHFGTR 579
Cdd:PRK03918  333 LE----EKEERLEELKK-------KLKELEKRLEELEE------RHELYEEAKAKKEELE-----------RLKKRLTGL 384

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  580 E-EMFQKEIKALHAATEKLSKENESLRSKldhankensdvialwKSKLETAIASHQQAMEELKVsfskgigtdsaefAEL 658
Cdd:PRK03918  385 TpEKLEKELEELEKAKEEIEEEISKITAR---------------IGELKKEIKELKKAIEELKK-------------AKG 436

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  659 KTQIERLRLDYQHEIESLQSkqdsersaHAKEMESMKAKLMKiIKEKEDSLEAVKARLDT--AEDQHLVEMEEMLSKLQE 736
Cdd:PRK03918  437 KCPVCGRELTEEHRKELLEE--------YTAELKRIEKELKE-IEEKERKLRKELRELEKvlKKESELIKLKELAEQLKE 507

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  737 AEIKVKE--LEVLQAKYSEQTQV---VGHLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEGAEKQIKNLEMERN 811
Cdd:PRK03918  508 LEEKLKKynLEELEKKAEEYEKLkekLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESV 587

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  812 AESSKANSITKDLQGKELMLTSLQSNLnevnqvkETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQK-----EEQ 886
Cdd:PRK03918  588 EELEERLKELEPFYNEYLELKDAEKEL-------EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELekkysEEE 660

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 672073054  887 FNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMK 934
Cdd:PRK03918  661 YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
PTZ00121 PTZ00121
MAEBL; Provisional
 343-966 5.70e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.63  E-value: 5.70e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  343 ARKISGTTALQEALKE-----KQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlaRDGHDQHVLELEAKMDQLRtmvE 417
Cdd:PTZ00121 1223 AKKAEAVKKAEEAKKDaeeakKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA--RKADELKKAEEKKKADEAK---K 1297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  418 AADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHARIKELEQSLlfEKTKADKLQREL 497
Cdd:PTZ00121 1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAE--EKAEAAEKKKEE 1375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  498 EDTRVATV----SEKSRIMELEKDLALRVQEVAELRRRLESSKPPGDVDMSLSLLQEISALQEKLE----VTHTDHQNEV 569
Cdd:PTZ00121 1376 AKKKADAAkkkaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEeakkADEAKKKAEE 1455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  570 TSLKDHFGTREEMFQKEIKALHAATEK-----LSKENESLRSKLDHANKENSDVialwKSKLETAIASHQQAMEELKVSF 644
Cdd:PTZ00121 1456 AKKAEEAKKKAEEAKKADEAKKKAEEAkkadeAKKKAEEAKKKADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAE 1531

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  645 SKGiGTDSAEFAELKTQIERLRldYQHEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEDQhl 724
Cdd:PTZ00121 1532 EAK-KADEAKKAEEKKKADELK--KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKK-- 1606

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  725 vEMEEMLSKLQEAEIKVKELEvlqaKYSEQTQVVGHLTSQlsvVEEQLLDLDALRKANSEGKLEIETLRQQLEGAEKQIK 804
Cdd:PTZ00121 1607 -MKAEEAKKAEEAKIKAEELK----KAEEEKKKVEQLKKK---EAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAE 1678

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  805 NLEMERNAESSKANSITKDLQGKElMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKE 884
Cdd:PTZ00121 1679 EAKKAEEDEKKAAEALKKEAEEAK-KAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK 1757

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  885 EQFNMLSSELEKLRENLTDMEAKFKEKDEREDqlvkakEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKL 964
Cdd:PTZ00121 1758 KIAHLKKEEEKKAEEIRKEKEAVIEEELDEED------EKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSA 1831


                  ..
gi 672073054  965 TK 966
Cdd:PTZ00121 1832 IK 1833
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 356-905 5.75e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 68.22  E-value: 5.75e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   356 LKEKQQHIEQLLAERDLE----RAEVAKATSHVGEIEQELALARDG-------HDQHVLELEAKMDQLRTMVEAADREKV 424
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEitglTEKASSARSQANSIQSQLEIIQEQarnqnsmYMRQLSDLESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   425 ELLNQLEEE---------KRKVEDLQFrvEEESITKGDLEQKSQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQR 495
Cdd:pfam15921  342 DKIEELEKQlvlanseltEARTERDQF--SQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRR 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   496 ELEDTRVATVSEKSRIM--------ELEKDLAL------RVQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEVT 561
Cdd:pfam15921  420 ELDDRNMEVQRLEALLKamksecqgQMERQMAAiqgkneSLEKVSSLTAQLESTK-----EMLRKVVEELTAKKMTLESS 494

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   562 HTDHQNEVTSLKDHFGTREEMfQKEIKALHAATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIASHQQA 636
Cdd:pfam15921  495 ERTVSDLTASLQEKERAIEAT-NAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALklqmaEKDKVIEILRQQIEN 573

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   637 MEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQhEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKaRL 716
Cdd:pfam15921  574 MTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ-EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVK-DI 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   717 DTAEDQHLVEMEEMLSKLQEAEikvKELEVLQAKYSEQTQVVGHLTSQLsvveeqlldldalrkansegKLEIETLRQQL 796
Cdd:pfam15921  652 KQERDQLLNEVKTSRNELNSLS---EDYEVLKRNFRNKSEEMETTTNKL--------------------KMQLKSAQSEL 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   797 EGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDT 876
Cdd:pfam15921  709 EQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580
                   ....*....|....*....|....*....
gi 672073054   877 VNKLHqkeeqfnMLSSELEKLRENLTDME 905
Cdd:pfam15921  789 AGELE-------VLRSQERRLKEKVANME 810
NIP100 COG5244
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ...
 60-121 9.55e-11

Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 227569 [Multi-domain]  Cd Length: 669  Bit Score: 67.02  E-value: 9.55e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672073054   60 VGERVWVNGNKpGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRP 121
Cdd:COG5244     6 VNDRVLLGDKF-GTVRFIGKTKFKDGIWIGLELDDPVGKNDGSVNGVRYFHCKKRHGIFIRP 66
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 335-807 1.11e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.11e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  335 LTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRT 414
Cdd:COG1196   283 LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  415 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQISEDPENTQTKLEHAR------IKELEQSLLFEKT 488
Cdd:COG1196   363 AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELeeleeaLAELEEEEEEEEE 442

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  489 KADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESSKPPGDVDMSLSLLQEiSALQEKLEVTHTDHQNE 568
Cdd:COG1196   443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYE-GFLEGVKAALLLAGLRG 521

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  569 VTSLKDHFGTREEMFQKEIKALHAA---------TEKLSKENESLRSK---------LDHANKENSDVIALWKSKLETAI 630
Cdd:COG1196   522 LAGAVAVLIGVEAAYEAALEAALAAalqnivvedDEVAAAAIEYLKAAkagratflpLDKIRARAALAAALARGAIGAAV 601

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  631 ASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLR----LDYQHEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKE 706
Cdd:COG1196   602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAEL 681

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  707 DSLEAVKARLDTAEDQHLVEMEEMLSKLQEAEIKVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEgk 786
Cdd:COG1196   682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP-- 759

                         490       500
                  ....*....|....*....|.
gi 672073054  787 LEIETLRQQLEGAEKQIKNLE 807
Cdd:COG1196   760 PDLEELERELERLEREIEALG 780
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
577-1153 2.75e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.83  E-value: 2.75e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  577 GTREEMFQKEIKALHAATEKLSKENESLRSKLDHANkENSDVIALWKSKLETAIASHQQAMEELkvsfskgigtdsaefA 656
Cdd:PRK02224  191 QLKAQIEEKEEKDLHERLNGLESELAELDEEIERYE-EQREQARETRDEADEVLEEHEERREEL---------------E 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  657 ELKTQIERLRLDyqheieslQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEavKARLDTAEDQHLVEMEEMLSklqe 736
Cdd:PRK02224  255 TLEAEIEDLRET--------IAETEREREELAEEVRDLRERLEELEEERDDLLA--EAGLDDADAEAVEARREELE---- 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  737 aeikvKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDA----LRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNA 812
Cdd:PRK02224  321 -----DRDEELRDRLEECRVAAQAHNEEAESLREDADDLEEraeeLREEAAELESELEEAREAVEDRREEIEELEEEIEE 395

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  813 ESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASE--EAVSTQTSMQDT-----VNKLHQKEE 885
Cdd:PRK02224  396 LRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAllEAGKCPECGQPVegsphVETIEEDRE 475

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  886 QFNMLSSELEKLRENLTDMEAKFkekdEREDQLVKAKEKLENdiaeimkmSGDNSSQLTKMNDElrlKERSVEELQLKLT 965
Cdd:PRK02224  476 RVEELEAELEDLEEEVEEVEERL----ERAEDLVEAEDRIER--------LEERREDLEELIAE---RRETIEEKRERAE 540

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  966 KANENASLLQKSiGEVTLKAEQSQQEAAKKHEEEKKELENKLLELEKKMEtSHYQCQDLKAKYEKASSETKIKHEEiLQN 1045
Cdd:PRK02224  541 ELRERAAELEAE-AEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE-SLERIRTLLAAIADAEDEIERLREK-REA 617

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1046 FQKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKAKsltylLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEkgs 1125
Cdd:PRK02224  618 LAELNDERRERLAEKRERKRELEAEFDEARIEEARED-----KERAEEYLEQVEEKLDELREERDDLQAEIGAVENE--- 689

                         570       580
                  ....*....|....*....|....*...
gi 672073054 1126 lLSKLIEVETKITLLQEDQQKLWSVNEN 1153
Cdd:PRK02224  690 -LEELEELRERREALENRVEALEALYDE 716
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1229-1769 4.53e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 4.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1229 DKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKD---DVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNL 1305
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1306 DNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLSASLEAT-LQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQT 1384
Cdd:COG1196   315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAeAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1385 SNTSLTKLLEEIKTCRAITDsECIQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRLEVSLNEKITYLT 1464
Cdd:COG1196   395 AAELAAQLEELEEAEEALLE-RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAA 473

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1465 SEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKR----------KYEQEATNRRLAVQEKVKLL 1534
Cdd:COG1196   474 LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgavavligveAAYEAALEAALAAALQNIVV 553

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1535 GNIDALKKELQQRKKENQELASskcdLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEEC 1614
Cdd:COG1196   554 EDDEVAAAAIEYLKAAKAGRAT----FLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1615 QKLNEEIREIQQTLMLEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTEnftltQEKTNSEQKVVEIIKE 1694
Cdd:COG1196   630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL-----AEEELELEEALLAEEE 704

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054 1695 KELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREMM 1769
Cdd:COG1196   705 EERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1184-2011 6.14e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 6.14e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1184 VEREKLLKEINVTQEELLKMHMEKDSLEASKVSM---QVLIEELRFCKDKLMAMSEKA------RAEKEQLEG-----QV 1249
Cdd:TIGR02169  153 VERRKIIDEIAGVAEFDRKKEKALEELEEVEENIerlDLIIDEKRQQLERLRREREKAeryqalLKEKREYEGyellkEK 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1250 KKLTAENMVLVKDKDD---VIQKLQSAYEELVKDQKALVQEIEDLTTE-KKSAAEKQMNLDNTCLTLKAERENLLQSNRD 1325
Cdd:TIGR02169  233 EALERQKEAIERQLASleeELEKLTEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVKEKIGELEAEIASLERSIAE 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1326 LQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQTSntsltklLEEIKTCRAITDS 1405
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE-------LEEVDKEFAETRD 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1406 ECIQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRLEvslnEKITYLTSEKEMACQKVARLKKQQDSLL 1485
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIE----AKINELEEEKEDKALEIKKQEWKLEQLA 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1486 KEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKK----------ELQQRKKENQ--- 1552
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKAsiqgvhgtvaQLGSVGERYAtai 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1553 ELASSKCDLSLMLKEAQTAKKNLE--KEHTSMMQAKEDLNaELKTCCCEKNILLRDG-----LNLQEECQKLNEEIREI- 1624
Cdd:TIGR02169  542 EVAAGNRLNNVVVEDDAVAKEAIEllKRRKAGRATFLPLN-KMRDERRDLSILSEDGvigfaVDLVEFDPKYEPAFKYVf 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1625 QQTLMLEKEARAKESESSLyesnklhgRIVLLEEEIqglrtcseqlqtenFTLTQEKTNSEQKVVEIIKEKELLSAETAQ 1704
Cdd:TIGR02169  621 GDTLVVEDIEAARRLMGKY--------RMVTLEGEL--------------FEKSGAMTGGSRAPRGGILFSRSEPAELQR 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1705 LAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEE 1784
Cdd:TIGR02169  679 LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1785 SYFVLQKEISQLAQTNSHISADLleAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEdamqiMEQMTKEKTETLASL 1864
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEAL--NDLEARLSHSRIPEIQAELSKLEEEVSRIEARLRE-----IEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1865 EDTKQTNAKLQSELDTLKENNLKTVEELNKskellneenqKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRT 1944
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNG----------KKEELEEELEELEAALRDLESRLGDLKKERDELEAQLREL 901

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672073054  1945 RDEVtshQKLEEERSVLNNQLLEMKKRESEYRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEV 2011
Cdd:TIGR02169  902 ERKI---EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEE 965
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 579-1366 7.03e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 7.03e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   579 REEMFQKEIKALHAATEKLSKENEslrskldhaNKENSDVIALWKSKLE-TAIASHQQAMEELKVSFSKGIGTDSAEFAE 657
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRRERE---------KAERYQALLKEKREYEgYELLKEKEALERQKEAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   658 LKTQIERLRLDYqHEIESLQS--------KQDSERSAHAKEMESMKAKLMKI---IKEKEDSLEAVKARLDTAE---DQH 723
Cdd:TIGR02169  256 LTEEISELEKRL-EEIEQLLEelnkkikdLGEEEQLRVKEKIGELEAEIASLersIAEKERELEDAEERLAKLEaeiDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   724 LVEMEEMLSKLQEaeiKVKELEVLQAKYSEQTQVVGHLTSQLSVVEEqllDLDALRKANSEGKLEIETLRQQLEGAEKQI 803
Cdd:TIGR02169  335 LAEIEELEREIEE---ERKRRDKLTEEYAELKEELEDLRAELEEVDK---EFAETRDELKDYREKLEKLKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   804 KNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEavstqtsmqdtvnkLHQK 883
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE--------------LYDL 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   884 EEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMsgdnSSQLTKMNdelrlkersvEELQLK 963
Cdd:TIGR02169  475 KEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGT----VAQLGSVG----------ERYATA 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   964 LTKANENAsllqksIGEVTLKAEQSQQEAAKKHEEEKKELENKLLELekkmetshyqcqdlkaKYEKASSETKIKHEEIL 1043
Cdd:TIGR02169  541 IEVAAGNR------LNNVVVEDDAVAKEAIELLKRRKAGRATFLPLN----------------KMRDERRDLSILSEDGV 598

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1044 QNFQKMLVDTEDKLKAA-QEANRD--LMQDMEELKSQ-----------------------ADKAKSLTYLLTSAKKEIEV 1097
Cdd:TIGR02169  599 IGFAVDLVEFDPKYEPAfKYVFGDtlVVEDIEAARRLmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQR 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1098 MSEELRGLKSEKQLFAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKLwsvNENLHLEKERIsEEKQVAEKRYQQEHR 1177
Cdd:TIGR02169  679 LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQL---EQEEEKLKERL-EELEEDLSSLEQEIE 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1178 DKESlvvEREKLLKEINVTQEELLKMHMEKDSLEASKVSMQvlIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENM 1257
Cdd:TIGR02169  755 NVKS---ELKELEARIEELEEDLHKLEEALNDLEARLSHSR--IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1258 VLvkdkDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQ 1337
Cdd:TIGR02169  830 YL----EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          810       820
                   ....*....|....*....|....*....
gi 672073054  1338 EKLSASLEATLQVKQLLSTEAETLRTQLD 1366
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELS 934
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 406-1136 1.77e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 63.21  E-value: 1.77e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   406 EAKMDQLRTMVEAADREKVELLnqLEEEKRKVEDLQFRVEEESitKGDLEQKSQISEDPENTQTKLEHARIKelEQSLLF 485
Cdd:pfam15921   58 EVELDSPRKIIAYPGKEHIERV--LEEYSHQVKDLQRRLNESN--ELHEKQKFYLRQSVIDLQTKLQEMQME--RDAMAD 131

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   486 EKTKADKLQRELEDTRVATVSEKSRIMELEKD-LALRVQEVAELRRRLESSKppgdvdmslSLLQEISALQEKLEVTHTD 564
Cdd:pfam15921  132 IRRRESQSQEDLRNQLQNTVHELEAAKCLKEDmLEDSNTQIEQLRKMMLSHE---------GVLQEIRSILVDFEEASGK 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   565 HQNEVTSLKD-HFGTREEMFQKEIKALHAATEKLSKENESLRSKLDHANKENsdvialwKSKLETAIASHQQAMEELKVS 643
Cdd:pfam15921  203 KIYEHDSMSTmHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSES-------QNKIELLLQQHQDRIEQLISE 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   644 FSKGIGTDSAEFAELKTQIERLrldyQHEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEDQH 723
Cdd:pfam15921  276 HEVEITGLTEKASSARSQANSI----QSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQL 351

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   724 LVEMEEMLSKLQEAEIKVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSegkLEIETLRQQLEGAEKQI 803
Cdd:pfam15921  352 VLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNS---ITIDHLRRELDDRNMEV 428

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   804 KNLEMERNAESSKANSITKD----LQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASeeavSTQTSMQDTVNK 879
Cdd:pfam15921  429 QRLEALLKAMKSECQGQMERqmaaIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLE----SSERTVSDLTAS 504

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   880 LHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLE---------NDIAEIMKMSGDNSSQLT------ 944
Cdd:pfam15921  505 LQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEalklqmaekDKVIEILRQQIENMTQLVgqhgrt 584

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   945 -------KMNDELRLKERSVEELQLKLTKANENASLLQKSIGEVTLKAEQSQQ-EAAKKHEEEKKELENKLLELEKKMET 1016
Cdd:pfam15921  585 agamqveKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLvNAGSERLRAVKDIKQERDQLLNEVKT 664

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1017 SHYQCQDLKAKYEKASSETKIKHEEILQNFQKMLVdtedKLKAAQ---EANRDLMQDMEELKSQADK-AKSLTYLLTSAK 1092
Cdd:pfam15921  665 SRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKM----QLKSAQselEQTRNTLKSMEGSDGHAMKvAMGMQKQITAKR 740

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 672073054  1093 KEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKLIEVETK 1136
Cdd:pfam15921  741 GQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATE 784
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1410-2010 2.20e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.03  E-value: 2.20e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1410 LLHEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRLEVSLNEkityLTSEKEMACQKVARLKKQQDSLLKEKS 1489
Cdd:COG1196   230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE----LELELEEAQAEEYELLAELARLEQDIA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1490 ALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKENQELASSkcdlslmLKEAQ 1569
Cdd:COG1196   306 RLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE-------LAEAE 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1570 TAKKNLEKEHTSMMQAKEDLNAELKTcccekniLLRDGLNLQEECQKLNEEIREIQQTLmLEKEARAKESESSLYESNKL 1649
Cdd:COG1196   379 EELEELAEELLEALRAAAELAAQLEE-------LEEAEEALLERLERLEEELEELEEAL-AELEEEEEEEEEALEEAAEE 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1650 HGRivlLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAAnietlKSDFAALSKSKLELQEL 1729
Cdd:COG1196   451 EAE---LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG-----FLEGVKAALLLAGLRGL 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1730 HSCLTKILDDLRLNHEVAVTERAEVLQdnkNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLE 1809
Cdd:COG1196   523 AGAVAVLIGVEAAYEAALEAALAAALQ---NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1810 AQSENRTLRKDkskLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTV 1889
Cdd:COG1196   600 AVDLVASDLRE---ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1890 EELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEmk 1969
Cdd:COG1196   677 AEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE-- 754

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|.
gi 672073054 1970 kresEYRKDADEEKAslqksisltsalltekDAELEKLRNE 2010
Cdd:COG1196   755 ----ELPEPPDLEEL----------------ERELERLERE 775
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1428-2006 2.62e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 62.73  E-value: 2.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1428 KEELLNENRVITEKLNKHSEEVTRLEVSLNEKITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQngdlLADRESSIK 1507
Cdd:TIGR04523  115 DKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKE----KLNIQKNID 190

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1508 AIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKE 1587
Cdd:TIGR04523  191 KIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1588 DLNAELKTCCcEKNILLRDGLN-LQEECQKLN----EEIREIQQTLMLEKEARAKESESSLYESNKlhgRIVLLEEEIQG 1662
Cdd:TIGR04523  271 EKQKELEQNN-KKIKELEKQLNqLKSEISDLNnqkeQDWNKELKSELKNQEKKLEEIQNQISQNNK---IISQLNEQISQ 346

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1663 LRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRL 1742
Cdd:TIGR04523  347 LKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEK 426

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1743 NHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKS 1822
Cdd:TIGR04523  427 EIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKK 506

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1823 KLTLKIRELETLHSF--TAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNA------KLQSELDTLKENNLKTVEELNK 1894
Cdd:TIGR04523  507 ELEEKVKDLTKKISSlkEKIEKLESEKKEKESKISDLEDELNKDDFELKKENlekeidEKNKEIEELKQTQKSLKKKQEE 586

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1895 SKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELgrtRDEVTSHQKLEEERSVLNNQLLEMKKRESE 1974
Cdd:TIGR04523  587 KQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSII---KNIKSKKNKLKQEVKQIKETIKEIRNKWPE 663

                          570       580       590
                   ....*....|....*....|....*....|..
gi 672073054  1975 YRKDADEEKASLQKSISLTSALLTEKDAELEK 2006
Cdd:TIGR04523  664 IIKKIKESKTKIDDIIELMKDWLKELSLHYKK 695
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 355-980 3.08e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.39  E-value: 3.08e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   355 ALKEKQQHIEQ--LLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEE 432
Cdd:TIGR02169  215 ALLKEKREYEGyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   433 EKRKVEdlqfrvEEESITKGDLEQKSQISEDPENTQTKLE------HARIKELEQSLLFEKTKADKLQRELEDTRVATVS 506
Cdd:TIGR02169  295 KIGELE------AEIASLERSIAEKERELEDAEERLAKLEaeidklLAEIEELEREIEEERKRRDKLTEEYAELKEELED 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   507 EKSRIMELEKDLALRVQEVAELRRRLESSKPPGDvdmslSLLQEISALQEKLEVTHT---DHQNEVTSLKD---HFGTRE 580
Cdd:TIGR02169  369 LRAELEEVDKEFAETRDELKDYREKLEKLKREIN-----ELKRELDRLQEELQRLSEelaDLNAAIAGIEAkinELEEEK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   581 EMFQKEIKA-------LHAATEKLSKENESLRSKLDHANKENSDVialwKSKLETAIASHQQAMEELKVSFS--KGIGTD 651
Cdd:TIGR02169  444 EDKALEIKKqewkleqLAADLSKYEQELYDLKEEYDRVEKELSKL----QRELAEAEAQARASEERVRGGRAveEVLKAS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   652 SAEFAELKTQIERLRLDYQHEIES------------------------------------LQSKQDSERSAHAKEMESMK 695
Cdd:TIGR02169  520 IQGVHGTVAQLGSVGERYATAIEVaagnrlnnvvveddavakeaiellkrrkagratflpLNKMRDERRDLSILSEDGVI 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   696 AKLMKIIKEKE----------------DSLEAVKA-----RLDTAED------------------------QHLVEMEEM 730
Cdd:TIGR02169  600 GFAVDLVEFDPkyepafkyvfgdtlvvEDIEAARRlmgkyRMVTLEGelfeksgamtggsraprggilfsrSEPAELQRL 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   731 LSKLQEAEikvKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLldlDALRKANSEGKLEIETLRQQLEGAEKQIKNLEMER 810
Cdd:TIGR02169  680 RERLEGLK---RELSSLQSELRRIENRLDELSQELSDASRKI---GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEI 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   811 NAESSKANSITKDLQGKELMLTSLQSNLNE-------------------VNQVKETLEKELQTLKEKFASASEEAVSTQT 871
Cdd:TIGR02169  754 ENVKSELKELEARIEELEEDLHKLEEALNDlearlshsripeiqaelskLEEEVSRIEARLREIEQKLNRLTLEKEYLEK 833

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   872 SMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELR 951
Cdd:TIGR02169  834 EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIE 913

                          730       740
                   ....*....|....*....|....*....
gi 672073054   952 LKERSVEELQLKLTKANENASLLQKSIGE 980
Cdd:TIGR02169  914 KKRKRLSELKAKLEALEEELSEIEDPKGE 942
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 725-1673 4.46e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.01  E-value: 4.46e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   725 VEMEEMLSKLQEAEIKVKELEVLQAKYSEQTQvvghltsQLSVVEEQLLDLDALRKanSEGKLEIETLRQQLEGAEKQIK 804
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLE-------RLRREREKAERYQALLK--EKREYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   805 NLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVN-QVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQK 883
Cdd:TIGR02169  241 AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNkKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   884 EEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLEndiaeimkmsgdnssqltkmnDELRLKERSVEELQLK 963
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK---------------------EELEDLRAELEEVDKE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   964 LTKANENASLLQKSIGEVTLKAEQSQQEaakkheeekkelenkllelekkmetshyqcqdlkakyEKASSETKIKHEEIL 1043
Cdd:TIGR02169  380 FAETRDELKDYREKLEKLKREINELKRE-------------------------------------LDRLQEELQRLSEEL 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1044 QNFQKMLVDTEDKLKAAQEANRDLmqdMEELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEK 1123
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDK---ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA 499

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1124 GSLLSKLIEVETKITLLQEDQQKLW-SVNENLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLK 1202
Cdd:TIGR02169  500 RASEERVRGGRAVEEVLKASIQGVHgTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLP 579

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1203 MH-MEKDSLEASKVSMQVLIE---ELRFCKDK-------------LMAMSEKARAekeqLEGQVKKLTAENMVLvkDKDD 1265
Cdd:TIGR02169  580 LNkMRDERRDLSILSEDGVIGfavDLVEFDPKyepafkyvfgdtlVVEDIEAARR----LMGKYRMVTLEGELF--EKSG 653

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1266 VIQKLQSAYEELVKDQKALVQEIEDLTTEKKSaaekqmnldntcltLKAERENLLQSNRDLQFEKDTLRQGQEKLSASLE 1345
Cdd:TIGR02169  654 AMTGGSRAPRGGILFSRSEPAELQRLRERLEG--------------LKRELSSLQSELRRIENRLDELSQELSDASRKIG 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1346 ATLQVKQLLSTEAETLRtqldcatkalRKAELDMRQLQTSNTSLTKLLEEIKTCRAItdseciqlLHEKESLAASERALL 1425
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLK----------ERLEELEEDLSSLEQEIENVKSELKELEAR--------IEELEEDLHKLEEAL 781

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1426 AEKEELLNENRV--ITEKLNKHSEEVTRLEVSLNE---KITYLTSEKEMACQKVARLKKQQDsllkeksALEVQNGDLLA 1500
Cdd:TIGR02169  782 NDLEARLSHSRIpeIQAELSKLEEEVSRIEARLREieqKLNRLTLEKEYLEKEIQELQEQRI-------DLKEQIKSIEK 854

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1501 DRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHT 1580
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS 934

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1581 SMmqakEDLNAELKTCCCEKNILLRdglnLQEECQKLNEEIREIQQTLMLEKEarakESESSLYESNKLHGRIVLLEEEI 1660
Cdd:TIGR02169  935 EI----EDPKGEDEEIPEEELSLED----VQAELQRVEEEIRALEPVNMLAIQ----EYEEVLKRLDELKEKRAKLEEER 1002

                          970
                   ....*....|...
gi 672073054  1661 QGLRTCSEQLQTE 1673
Cdd:TIGR02169 1003 KAILERIEEYEKK 1015
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 454-1307 9.88e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 60.76  E-value: 9.88e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   454 LEQKSQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRrrle 533
Cdd:pfam02463  178 LIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI---- 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   534 sskppgdvdmsLSLLQEISALQEKLEVTHTDHQNEvtslkdhfgTREEMFQKEIKALHAATEKLSKENESLRSKLDHANK 613
Cdd:pfam02463  254 -----------ESSKQEIEKEEEKLAQVLKENKEE---------EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   614 ENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQdsERSAHAKEMES 693
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKK--LESERLSSAAK 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   694 MKAKLMKIIKEKEDSLEAVKARLDTAEDQHLVEMEEMLSKLQEAEiKVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLL 773
Cdd:pfam02463  392 LKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEE-ESIELKQGKLTEEKEELEKQELKLLKDELELKKS 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   774 DLDALRKANSEGKLEIETLRQQLEGAE---KQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEK 850
Cdd:pfam02463  471 EDLLKETQLVKLQEQLELLLSRQKLEErsqKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVI 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   851 ELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAkEKLENDIA 930
Cdd:pfam02463  551 VEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR-AKVVEGIL 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   931 EIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKAN---------ENASLLQKSIGEVTLKAEQSQQEAAKKHEEEKK 1001
Cdd:pfam02463  630 KDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASlseltkellEIQELQEKAESELAKEEILRRQLEIKKKEQREK 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1002 ELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEILQNFQKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKA 1081
Cdd:pfam02463  710 EELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVE 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1082 KSLTYLLTSAKKEIEVMSEElrgLKSEKQLFAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNENLHLEKERI 1161
Cdd:pfam02463  790 EEKEEKLKAQEEELRALEEE---LKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1162 SEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKMHMEKDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAE 1241
Cdd:pfam02463  867 ELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEAD 946

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1242 KEQLEGQVKKLTAENMVLVKDKDD----VIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDN 1307
Cdd:pfam02463  947 EKEKEENNKEEEEERNKRLLLAKEelgkVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETC 1016
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 838-1885 1.15e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 60.57  E-value: 1.15e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   838 LNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQ 917
Cdd:pfam01576   14 LQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   918 LVKAKEKLENDI-------------------------AEIMKMSGD---NSSQLTKMNDELRLKERSVEELQLKLTKANE 969
Cdd:pfam01576   94 LQNEKKKMQQHIqdleeqldeeeaarqklqlekvtteAKIKKLEEDillLEDQNSKLSKERKLLEERISEFTSNLAEEEE 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   970 NAsllqKSIGEVTLKAE---QSQQEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEiLQNF 1046
Cdd:pfam01576  174 KA----KSLSKLKNKHEamiSDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEE-LQAA 248

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1047 QKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKAKSLTyllTSAKKEIEVMSEELRGLKSEKQ------LFAQEASALK 1120
Cdd:pfam01576  249 LARLEEETAQKNNALKKIRELEAQISELQEDLESERAAR---NKAEKQRRDLGEELEALKTELEdtldttAAQQELRSKR 325

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1121 LEKGSLLSKLIEVETKI--TLLQEDQQKLWSVNENLHLEKERISEEKQVAEKryqqehrDKESLVVEREKLLKEINVTQE 1198
Cdd:pfam01576  326 EQEVTELKKALEEETRSheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEK-------AKQALESENAELQAELRTLQQ 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1199 ELLKMHMEKDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKDDVIQKLQSAYEELV 1278
Cdd:pfam01576  399 AKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQ 478

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1279 KDQKALVQeiedLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEA 1358
Cdd:pfam01576  479 EETRQKLN----LSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQREL 554

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1359 ETLRTQLDCATKALRKAELDMRQLQTSNTSLTklleeiktcraitdsecIQLLHEKESLAASERAlLAEKEELLNENRVI 1438
Cdd:pfam01576  555 EALTQQLEEKAAAYDKLEKTKNRLQQELDDLL-----------------VDLDHQRQLVSNLEKK-QKKFDQMLAEEKAI 616

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1439 TeklNKHSEEVTRLEVSLNEKITyltsekemacqKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDL------ 1512
Cdd:pfam01576  617 S---ARYAEERDRAEAEAREKET-----------RALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVgknvhe 682

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1513 ----KRKYEQEATNRRLAVQE-----------KVKLLGNIDALK----KELQQRKKENQElasSKCDLSLMLKEAQTAKK 1573
Cdd:pfam01576  683 lersKRALEQQVEEMKTQLEEledelqatedaKLRLEVNMQALKaqfeRDLQARDEQGEE---KRRQLVKQVRELEAELE 759

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1574 NLEKEHTSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEECQKLNEEIREIQQTLMLEKEAR------AKESESSLyesN 1647
Cdd:pfam01576  760 DERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRdeilaqSKESEKKL---K 836

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1648 KLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQ 1727
Cdd:pfam01576  837 NLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKST 916

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1728 ELHSCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREMmlrnEEVLKEKEKLEESYFVlqkeiSQLAQTNSHISADL 1807
Cdd:pfam01576  917 LQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEM----EGTVKSKFKSSIAALE-----AKIAQLEEQLEQES 987

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1808 LEAQSENRTLRKDKSKL--TLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENN 1885
Cdd:pfam01576  988 RERQAANKLVRRTEKKLkeVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESN 1067
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1040-1834 1.18e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 1.18e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1040 EEILQNFQKMLVDTEDKLKAAQEANRDLMQDMEELKSQA-----DKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQ 1114
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEqlrvkEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1115 EASALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEIN 1194
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELD 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1195 VTQEELLKMHMEKDSLEASkvsmqvlIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAEnmvlVKDKDDVIQKLQSAY 1274
Cdd:TIGR02169  410 RLQEELQRLSEELADLNAA-------IAGIEAKINELEEEKEDKALEIKKQEWKLEQLAAD----LSKYEQELYDLKEEY 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1275 EELVKDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDL-QFEKDTLRQGQEKLSASLEATLQVKQL 1353
Cdd:TIGR02169  479 DRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLgSVGERYATAIEVAAGNRLNNVVVEDDA 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1354 LSTEAetlrTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRAITDSECiqllhEKESLAASERAL--------L 1425
Cdd:TIGR02169  559 VAKEA----IELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEF-----DPKYEPAFKYVFgdtlvvedI 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1426 AEKEELLNENRVIT---EKLNKhSEEVTRLEVSLNEKITYLTSEKEMACQKVAR---LKKQQDSLLKEKSALEVQNGDLL 1499
Cdd:TIGR02169  630 EAARRLMGKYRMVTlegELFEK-SGAMTGGSRAPRGGILFSRSEPAELQRLRERlegLKRELSSLQSELRRIENRLDELS 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1500 ADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKeH 1579
Cdd:TIGR02169  709 QELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA-R 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1580 TSMMQAKEdlnaelktccceknillrdglnLQEECQKLNEEIREIqqtlmlekEARAKESESSLyesNKLHGRIVLLEEE 1659
Cdd:TIGR02169  788 LSHSRIPE----------------------IQAELSKLEEEVSRI--------EARLREIEQKL---NRLTLEKEYLEKE 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1660 IQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDD 1739
Cdd:TIGR02169  835 IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEK 914

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1740 LRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVLKEkEKLEESYFVLQKEISQLAQTN-------SHISADLLEAQS 1812
Cdd:TIGR02169  915 KRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRALEPVNmlaiqeyEEVLKRLDELKE 993

                          810       820
                   ....*....|....*....|..
gi 672073054  1813 ENRTLRKDKSKLTLKIRELETL 1834
Cdd:TIGR02169  994 KRAKLEEERKAILERIEEYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 372-1192 1.42e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.47  E-value: 1.42e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   372 LERAEVAKATSHVGEIEQELALARDGHDqhvlELEAKMDQLRTMVEaadrEKVELLNQLEEEKRKVEdlqfRVEEESITK 451
Cdd:TIGR02169  153 VERRKIIDEIAGVAEFDRKKEKALEELE----EVEENIERLDLIID----EKRQQLERLRREREKAE----RYQALLKEK 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   452 GDLEQKSQISEDPEN-TQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQ-EVAELR 529
Cdd:TIGR02169  221 REYEGYELLKEKEALeRQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKeKIGELE 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   530 RRLESSKppGDVDMSLSLLQEISALQEKLEVTHTDHQNEVTSLKdhfgTREEMFQKEIKALHAATEKLSKENESLRSKLD 609
Cdd:TIGR02169  301 AEIASLE--RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE----REIEEERKRRDKLTEEYAELKEELEDLRAELE 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   610 HANKENsdviALWK---SKLETAIASHQQAMEELKVSFSKGIGTD---SAEFAELKTQIERlrldyqheIESLQSKQDSE 683
Cdd:TIGR02169  375 EVDKEF----AETRdelKDYREKLEKLKREINELKRELDRLQEELqrlSEELADLNAAIAG--------IEAKINELEEE 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   684 RSAHAKEMESMKAKLMKIIKEKED---SLEAVKARLDTAEDqhlvEMEEMLSKLQEAEIKVKELEVLQAKYSEQTQVVGH 760
Cdd:TIGR02169  443 KEDKALEIKKQEWKLEQLAADLSKyeqELYDLKEEYDRVEK----ELSKLQRELAEAEAQARASEERVRGGRAVEEVLKA 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   761 -------LTSQLSVVEEQLL------------------DLDA-------------------LRKANSEGK---------- 786
Cdd:TIGR02169  519 siqgvhgTVAQLGSVGERYAtaievaagnrlnnvvvedDAVAkeaiellkrrkagratflpLNKMRDERRdlsilsedgv 598

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   787 ----LEIETLRQQLEGAEKQI-------KNLEMERNAESS------------KANSIT---KDLQGKELMLTSLQSNLNE 840
Cdd:TIGR02169  599 igfaVDLVEFDPKYEPAFKYVfgdtlvvEDIEAARRLMGKyrmvtlegelfeKSGAMTggsRAPRGGILFSRSEPAELQR 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   841 VNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDeredqlvk 920
Cdd:TIGR02169  679 LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE-------- 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   921 akEKLENDIAEimkmsgdnssqLTKMNDELRLKERSVEELQLKLT--KANENASLLQKSIGEVT-LKAEQSQQEAAKKHE 997
Cdd:TIGR02169  751 --QEIENVKSE-----------LKELEARIEELEEDLHKLEEALNdlEARLSHSRIPEIQAELSkLEEEVSRIEARLREI 817

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   998 EEKKELENKLLELEKKmETSHYQCQDLKAKYEKASSETKIkheeilQNFQKMLVDTEDKLKAAQEANRDLMQDMEELKSQ 1077
Cdd:TIGR02169  818 EQKLNRLTLEKEYLEK-EIQELQEQRIDLKEQIKSIEKEI------ENLNGKKEELEEELEELEAALRDLESRLGDLKKE 890

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1078 ADKaksltylltsAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVnENLHLE 1157
Cdd:TIGR02169  891 RDE----------LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSL-EDVQAE 959

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|..
gi 672073054  1158 KERISEEKQ-------VAEKRYQQEHRDKESLVVEREKLLKE 1192
Cdd:TIGR02169  960 LQRVEEEIRalepvnmLAIQEYEEVLKRLDELKEKRAKLEEE 1001
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1206-1947 1.50e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 60.13  E-value: 1.50e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1206 EKDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKDDVIQKLQSAYEELVK---DQK 1282
Cdd:pfam15921  104 QKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKmmlSHE 183

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1283 ALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSN--RDLQFEKDTLRQGQEKLSASLEAtlqvkqlLSTEAET 1360
Cdd:pfam15921  184 GVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKilRELDTEISYLKGRIFPVEDQLEA-------LKSESQN 256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1361 lrtqldcatkalrKAELDMRQLQTSNTSLtklleeiktcraITDSEC-IQLLHEKESLAASERALLAEKEELL-----NE 1434
Cdd:pfam15921  257 -------------KIELLLQQHQDRIEQL------------ISEHEVeITGLTEKASSARSQANSIQSQLEIIqeqarNQ 311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1435 NRVITEKLNKHSEEVTRLEVSLNE-------KITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIK 1507
Cdd:pfam15921  312 NSMYMRQLSDLESTVSQLRSELREakrmyedKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREK 391

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1508 aigDLKRKYEQeatNRRLAVQEKVKLLgNIDALKKELQQRKKENQELAS------SKCDLSLMLKEAQTAKKNLEKEHTS 1581
Cdd:pfam15921  392 ---ELSLEKEQ---NKRLWDRDTGNSI-TIDHLRRELDDRNMEVQRLEAllkamkSECQGQMERQMAAIQGKNESLEKVS 464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1582 MMQAKEDLNAELKTCCCEKnillrdglnLQEECQKLNEEIREIQQ-TLMLEKEARAKESESSlyESNKLHGRIVLLEEEI 1660
Cdd:pfam15921  465 SLTAQLESTKEMLRKVVEE---------LTAKKMTLESSERTVSDlTASLQEKERAIEATNA--EITKLRSRVDLKLQEL 533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1661 QGLRTCSEQL---QTENFTLTQEKTNSEqKVVEIIKEK-ELLSAETAQLAANIETLKSDFAALSKS----KLELQELHSC 1732
Cdd:pfam15921  534 QHLKNEGDHLrnvQTECEALKLQMAEKD-KVIEILRQQiENMTQLVGQHGRTAGAMQVEKAQLEKEindrRLELQEFKIL 612

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1733 ----------LTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEI----SQLAQ 1798
Cdd:pfam15921  613 kdkkdakireLEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFrnksEEMET 692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1799 TNSHISADLLEAQSEnrtlrKDKSKLTLKIRELETLHSFTAAqtaedaMQIMEQMTKEKTETLAsledtkqtnakLQSEL 1878
Cdd:pfam15921  693 TTNKLKMQLKSAQSE-----LEQTRNTLKSMEGSDGHAMKVA------MGMQKQITAKRGQIDA-----------LQSKI 750

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672073054  1879 DTLKEnnlkTVEELNKSKELLNEENQKMeefkkeietlkqaaaqkSQQLSALQEENVKLAEELGRTRDE 1947
Cdd:pfam15921  751 QFLEE----AMTNANKEKHFLKEEKNKL-----------------SQELSTVATEKNKMAGELEVLRSQ 798
PTZ00121 PTZ00121
MAEBL; Provisional
 683-1492 2.40e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.77  E-value: 2.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  683 ERSAHAKEMESMKAKLMKI---IKEKEDSLEAVKARLDTAEDQHLVEMEEMLSKLQEAEIKVKELEVLQAKYSEQTQVVG 759
Cdd:PTZ00121 1061 EAKAHVGQDEGLKPSYKDFdfdAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDAR 1140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  760 HLTSQLSVVEEQLLDLDalRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNAESSKANSITKdlqGKELMLTSLQSNLN 839
Cdd:PTZ00121 1141 KAEEARKAEDAKRVEIA--RKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARK---AEAARKAEEERKAE 1215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  840 EVNQVKETLEKELQTLKEKFASASEEAvstqtsmqdtvnKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDERE-DQL 918
Cdd:PTZ00121 1216 EARKAEDAKKAEAVKKAEEAKKDAEEA------------KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKaDEL 1283

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  919 VKAKEKLENDIAEimkmsgdnSSQLTKMNDELRLK---ERSVEELQLKLTKANENASLLQKSIGEVTLKAEQSQQEAAKK 995
Cdd:PTZ00121 1284 KKAEEKKKADEAK--------KAEEKKKADEAKKKaeeAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAA 1355

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  996 HEEEKKELENKLLELEKKMETSHyQCQDLKAKYE--KASSETKIKHEEILQNFQKMLVDTEDKLKAAQEANR-DLMQDME 1072
Cdd:PTZ00121 1356 ADEAEAAEEKAEAAEKKKEEAKK-KADAAKKKAEekKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKaEEKKKAD 1434

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1073 ELKSQADKAKSLTYLLTSAKK-----EIEVMSEELRGLKSEKQLFAQEASALKLEK-GSLLSKLIEVETKITLLQEDQQK 1146
Cdd:PTZ00121 1435 EAKKKAEEAKKADEAKKKAEEakkaeEAKKKAEEAKKADEAKKKAEEAKKADEAKKkAEEAKKKADEAKKAAEAKKKADE 1514

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1147 LWSVNENLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKMHMEKDSLEASKVSMQVLIEELRF 1226
Cdd:PTZ00121 1515 AKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI 1594

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1227 CKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLD 1306
Cdd:PTZ00121 1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1307 NTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTqldcATKALRKAELDMRQLQTSN 1386
Cdd:PTZ00121 1675 KKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIK----AEEAKKEAEEDKKKAEEAK 1750

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1387 TSLTkllEEIKTCRAITDSECIQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRlevSLNEKITYLTSE 1466
Cdd:PTZ00121 1751 KDEE---EKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIE---GGKEGNLVINDS 1824

                         810       820
                  ....*....|....*....|....*.
gi 672073054 1467 KEMACQKVARLKKQQDSLLKEKSALE 1492
Cdd:PTZ00121 1825 KEMEDSAIKEVADSKNMQLEEADAFE 1850
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1472-2046 2.41e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 2.41e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1472 QKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKEN 1551
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERL 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1552 QELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELKTcccEKNILLRDGLNLQEECQKLNEEIREIQQTLMLE 1631
Cdd:COG1196   319 EELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE---AEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1632 KEARAKESEsslyesnklhgrivlLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIET 1711
Cdd:COG1196   396 AELAAQLEE---------------LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1712 LKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQDNKN-LLAEKREMMLRNEEVLKEKEKLEESYFVLQ 1790
Cdd:COG1196   461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEAAL 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1791 KEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTlkIRELETLHSFTAAQTAEDAMQIMEqmtkektETLASLEDTKQT 1870
Cdd:COG1196   541 EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAT--FLPLDKIRARAALAAALARGAIGA-------AVDLVASDLREA 611

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1871 NAKLQSELDTLKENNLKTVEELNKSKELLNEENqkmeefkKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTS 1950
Cdd:COG1196   612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAG-------RLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1951 HQKLEEERSVLNNQLLEMKKRESEYRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQT 2030
Cdd:COG1196   685 AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEE 764

                         570
                  ....*....|....*.
gi 672073054 2031 LESDKVKLELKVKNLE 2046
Cdd:COG1196   765 LERELERLEREIEALG 780
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 878-1705 2.99e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 2.99e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   878 NKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAeiMKMSGDNSSQLTKMNDELRLKERSV 957
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLY--LDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   958 EELQLKLTKANENASLLQKSIGEVTlKAEQSQQEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKI 1037
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEE-KEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKK 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1038 KHEEILQnFQKMLVDTEDKLKAAQEANRDLMQDME--ELKSQADKAKSLTY------LLTSAKKEIEVMSEELRGLKSEK 1109
Cdd:pfam02463  333 EKEEIEE-LEKELKELEIKREAEEEEEEELEKLQEklEQLEEELLAKKKLEserlssAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1110 QLFAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNENLHLEK----------ERISEEKQVAEKRYQQEHRDK 1179
Cdd:pfam02463  412 ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLlkdelelkksEDLLKETQLVKLQEQLELLLS 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1180 ESLVVEREKLLKEINVTQ--EELLKMHMEKDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENM 1257
Cdd:pfam02463  492 RQKLEERSQKESKARSGLkvLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALT 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1258 VLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQ 1337
Cdd:pfam02463  572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1338 EKLSASLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRAITDSECIQLLHEKESL 1417
Cdd:pfam02463  652 VSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQ 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1418 AASERALLAEKEELLNENRVITEKLNKHSEEVTRlEVSLNEKITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGD 1497
Cdd:pfam02463  732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEE-KSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEEL 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1498 LLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEK 1577
Cdd:pfam02463  811 KEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELES 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1578 EHTSMMQAKEDLNAELKTCCcekNILLRDGLNLQEECQKLNEEIREIQQTLMLEKEARAKESESSLYESNKLHgRIVLLE 1657
Cdd:pfam02463  891 KEEKEKEEKKELEEESQKLN---LLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE-RNKRLL 966

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*...
gi 672073054  1658 EEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQL 1705
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEE 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 344-991 3.24e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.31  E-value: 3.24e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   344 RKISGTTALQEALKEKQQHIEQLLAE-----RDLERAEVAKATSHVGEIEQELALARDGHDQHVLELE------------ 406
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEElnkkiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEdaeerlakleae 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   407 -----AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQiSEDPENTQTKLEHARIKELEQ 481
Cdd:TIGR02169  331 idkllAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK-DYREKLEKLKREINELKRELD 409

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   482 SLLFEKTKADKlqrELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLES-SKPPGDVDMSLSLLQ--------EIS 552
Cdd:TIGR02169  410 RLQEELQRLSE---ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQlAADLSKYEQELYDLKeeydrvekELS 486

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   553 ALQEKLEVTHTDHQNEVTSLKDHFGTrEEMFQKEIKALHAATEKLSKENESLRSKLDHA--NKENSDVIAlwksklETAI 630
Cdd:TIGR02169  487 KLQRELAEAEAQARASEERVRGGRAV-EEVLKASIQGVHGTVAQLGSVGERYATAIEVAagNRLNNVVVE------DDAV 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   631 AshQQAMEELKvsfSKGIGtdSAEFAEL-KTQIERLRLDYQHEIESLQSKQD----SERSAHA-----------KEMESM 694
Cdd:TIGR02169  560 A--KEAIELLK---RRKAG--RATFLPLnKMRDERRDLSILSEDGVIGFAVDlvefDPKYEPAfkyvfgdtlvvEDIEAA 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   695 KAKLMKI--------IKEKEDSLEAVKARLDTAEDQHLVEMEEMLSKLQEAEIKVKELEVLQAKYSEQTQVVGHLTSQLS 766
Cdd:TIGR02169  633 RRLMGKYrmvtlegeLFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELS 712

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   767 VVEEQlldLDALRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQvkE 846
Cdd:TIGR02169  713 DASRK---IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA--R 787

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   847 TLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLE 926
Cdd:TIGR02169  788 LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELE 867

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054   927 NDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASLLQKSIGEVTLKAEQSQQE 991
Cdd:TIGR02169  868 EELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 371-932 3.27e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 3.27e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  371 DLERAEVAKATSHVGEIEQELALARDGHDqhvlELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESIT 450
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELE----ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  451 KGDLEQKsqisEDPENTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRR 530
Cdd:COG1196   297 LARLEQD----IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  531 RLESskppgDVDMSLSLLQEISALQEKLEVTHTDHQNEVTSLKDHFGTREEMfQKEIKALHAATEKLSKENESLRSKLDH 610
Cdd:COG1196   373 ELAE-----AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL-EEELEELEEALAELEEEEEEEEEALEE 446

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  611 ANKENSDVIALwKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIErLRLDYQHEIESLQSKQDSERSAH--- 687
Cdd:COG1196   447 AAEEEAELEEE-EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE-AEADYEGFLEGVKAALLLAGLRGlag 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  688 -------------AKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEDQHLVEMEEMLSKLQEAEIKVKELEVLQAKYSEQ 754
Cdd:COG1196   525 avavligveaayeAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  755 TQVVGHLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSL 834
Cdd:COG1196   605 ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  835 QSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDtvnKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDER 914
Cdd:COG1196   685 AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA---LEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                         570
                  ....*....|....*...
gi 672073054  915 EDQLVKAKEKLENDIAEI 932
Cdd:COG1196   762 LEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1539-2102 3.62e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.18  E-value: 3.62e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1539 ALKKELQQRKkenQELASSKcdlslmLKEAQTAKKNLEKEHTSMMQAKEDLNAELKtccceknillrdglNLQEECQKLN 1618
Cdd:COG1196   217 ELKEELKELE---AELLLLK------LRELEAELEELEAELEELEAELEELEAELA--------------ELEAELEELR 273

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1619 EEIREIQQTLmleKEARAKESESSLyESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELL 1698
Cdd:COG1196   274 LELEELELEL---EEAQAEEYELLA-ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA 349

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1699 SAETAQLAANIETLKSDFAALSKSKLELQELhscltkiLDDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVLKE 1778
Cdd:COG1196   350 EEELEEAEAELAEAEEALLEAEAELAEAEEE-------LEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEE 422

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1779 KEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLHS------FTAAQTAEDAMQIMEQ 1852
Cdd:COG1196   423 LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAelleelAEAAARLLLLLEAEAD 502

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1853 MTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAA--------QKS 1924
Cdd:COG1196   503 YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratflplDKI 582

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1925 QQLSALQEENVKLAEELGR-------------------TRDEVTSHQKLEEERSVLNNQLLEMKKRESEYRKDADEEKAS 1985
Cdd:COG1196   583 RARAALAAALARGAIGAAVdlvasdlreadaryyvlgdTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSL 662

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1986 LQKSISLTSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDV 2065
Cdd:COG1196   663 TGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL 742

                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 672073054 2066 QTEEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMM 2102
Cdd:COG1196   743 EEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 760-1628 5.06e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 5.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   760 HLTSQLSVVEEQLLDLDA-LRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNA-------ESSKANSITKDLQG----- 826
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRrLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAmadirrrESQSQEDLRNQLQNtvhel 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   827 ------KELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASAsEEAVSTQTSMQDTVNKLHqkeeqFNMLSSELEK-LRE 899
Cdd:pfam15921  155 eaakclKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDF-EEASGKKIYEHDSMSTMH-----FRSLGSAISKiLRE 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   900 NLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLtkmndelrlkersVEELQLKLTKANENASLLQKSIG 979
Cdd:pfam15921  229 LDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQL-------------ISEHEVEITGLTEKASSARSQAN 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   980 EVTLKAEQSQQEAAKkheeekkelenkllelekkmETSHYQCQ--DLKAKYEKASSETKikheeilqnfqkmlvdtedkl 1057
Cdd:pfam15921  296 SIQSQLEIIQEQARN--------------------QNSMYMRQlsDLESTVSQLRSELR--------------------- 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1058 kaaqEANRDLMQDMEELKSQADKAKSltylltsakkeievmseELRGLKSEKQLFAQEASALKLEKGSLLSKLIEVETKI 1137
Cdd:pfam15921  335 ----EAKRMYEDKIEELEKQLVLANS-----------------ELTEARTERDQFSQESGNLDDQLQKLLADLHKREKEL 393

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1138 TLLQEDQQKLWSVNENlhlekeriseeKQVAEKRYQQEHRDKESLVVEREKLLKEINV-----TQEELLKMHMEKDSLEa 1212
Cdd:pfam15921  394 SLEKEQNKRLWDRDTG-----------NSITIDHLRRELDDRNMEVQRLEALLKAMKSecqgqMERQMAAIQGKNESLE- 461

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1213 sKVSMqvLIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLvKDKDDVIQKLQSAYEELVKDQKALVQEIEDLT 1292
Cdd:pfam15921  462 -KVSS--LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASL-QEKERAIEATNAEITKLRSRVDLKLQELQHLK 537

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1293 TEKKSAAEKQMNLDNTCLTLkAERENLLQSNRDlQFEKDTLRQGQEKLSASleATLQVKQLLSTEAETLRTQLDCATKAL 1372
Cdd:pfam15921  538 NEGDHLRNVQTECEALKLQM-AEKDKVIEILRQ-QIENMTQLVGQHGRTAG--AMQVEKAQLEKEINDRRLELQEFKILK 613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1373 RKAELDMRQLQTSNTSLTklLEEIKTCRAitdseciqllhEKESLAASeRALLAEKEELLNENRVITEKLNKHSEEVTRL 1452
Cdd:pfam15921  614 DKKDAKIRELEARVSDLE--LEKVKLVNA-----------GSERLRAV-KDIKQERDQLLNEVKTSRNELNSLSEDYEVL 679

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1453 EVSLNEKitylTSEKEMACQKVA-RLKKQQDSLLKEKSALEVQNGdllADRESSIKAIGdlkrkYEQEATNRRlavqekv 1531
Cdd:pfam15921  680 KRNFRNK----SEEMETTTNKLKmQLKSAQSELEQTRNTLKSMEG---SDGHAMKVAMG-----MQKQITAKR------- 740

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1532 kllGNIDALKKELQqrkkenqelasskcdlslMLKEAQTakkNLEKEHTSMMQAKEDLNAELKTCCCEKNILLRDGLNLQ 1611
Cdd:pfam15921  741 ---GQIDALQSKIQ------------------FLEEAMT---NANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLR 796

                          890
                   ....*....|....*..
gi 672073054  1612 EECQKLNEEIREIQQTL 1628
Cdd:pfam15921  797 SQERRLKEKVANMEVAL 813
PTZ00121 PTZ00121
MAEBL; Provisional
 415-1185 6.37e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.23  E-value: 6.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  415 MVEAADREKVELLNQLEEEKRKVEdlQFRVEEESitkgDLEQKSQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQ 494
Cdd:PTZ00121 1084 KEDNRADEATEEAFGKAEEAKKTE--TGKAEEAR----KAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIA 1157

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  495 RELEDTRVATVSEKSRimelEKDLALRVQEVAELRRRLESSKPpgdvdmslsllQEISALQEKLEVTHTDHQNEVTSLKD 574
Cdd:PTZ00121 1158 RKAEDARKAEEARKAE----DAKKAEAARKAEEVRKAEELRKA-----------EDARKAEAARKAEEERKAEEARKAED 1222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  575 hfgtreemfQKEIKALHAATEKLSKENESLRSKLDHANKE----NSDVIALWKSKLETAIASHQQAMEELKVSFSKGiGT 650
Cdd:PTZ00121 1223 ---------AKKAEAVKKAEEAKKDAEEAKKAEEERNNEEirkfEEARMAHFARRQAAIKAEEARKADELKKAEEKK-KA 1292

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  651 DSAEFAELKTQIERLRLDYQheieslQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEDqhlvEMEEM 730
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAE------EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD----EAEAA 1362

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  731 LSKLQEAEIKVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQqlegAEKQIKNLEMER 810
Cdd:PTZ00121 1363 EEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKK----AEEKKKADEAKK 1438

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  811 NAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKekfasaSEEAVSTQTSMQDTVNKLHQKEEQfNML 890
Cdd:PTZ00121 1439 KAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKK------ADEAKKKAEEAKKKADEAKKAAEA-KKK 1511

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  891 SSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDiaEIMKMSGDNSSQLTKMNDElrlKERSVEELQLKLTKANEN 970
Cdd:PTZ00121 1512 ADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD--ELKKAEELKKAEEKKKAEE---AKKAEEDKNMALRKAEEA 1586

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  971 ASLLQKSIGEVTLKAEQSQQEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEilqnfqkml 1050
Cdd:PTZ00121 1587 KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEE--------- 1657

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1051 vdtEDKLKAAQEANRDlmqdmEELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKL 1130
Cdd:PTZ00121 1658 ---ENKIKAAEEAKKA-----EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK 1729

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 672073054 1131 IEVETKITLLQEDQQKLWSVNENlHLEKERISEEKQVAEKRYQQEHRDKESLVVE 1185
Cdd:PTZ00121 1730 IKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
775-1401 6.59e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.15  E-value: 6.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  775 LDALRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLnevnqvketleKELQT 854
Cdd:PRK03918  167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV-----------KELEE 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  855 LKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEaKFKEKDEREDQLVKAKEKLENDIAEIMK 934
Cdd:PRK03918  236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEK 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  935 MSGDNSSQLtkmndelrlkersvEELQLKLTKANEnaslLQKSIGEVTLKAEQSQQEAAKkheeekkelenkllelekkM 1014
Cdd:PRK03918  315 RLSRLEEEI--------------NGIEERIKELEE----KEERLEELKKKLKELEKRLEE-------------------L 357

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1015 ETSHYQCQDLKAKYEKASSETKIKHEEILQNFQKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKAKSLTYLLTSAKKE 1094
Cdd:PRK03918  358 EERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGK 437

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1095 IEVMSEELRGlKSEKQLFAQeasaLKLEKGSLLSKLIEVETKITLLQEDQQKLwsvnENLHLEKERISEEKQVAEKRYQQ 1174
Cdd:PRK03918  438 CPVCGRELTE-EHRKELLEE----YTAELKRIEKELKEIEEKERKLRKELREL----EKVLKKESELIKLKELAEQLKEL 508

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1175 EHRDKESLVVEREKLLKEINVTQEELLKMHMEKDSLEASkvsmqvlIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTA 1254
Cdd:PRK03918  509 EEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKE-------LEKLEELKKKLAELEKKLDELEEELAELLKELEE 581

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1255 ENMVLVKDKDDVIQKLQSAYEELV------KDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQF 1328
Cdd:PRK03918  582 LGFESVEELEERLKELEPFYNEYLelkdaeKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY 661

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672073054 1329 EKdtLRQGQEKLS---ASLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRA 1401
Cdd:PRK03918  662 EE--LREEYLELSrelAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKA 735
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1773-2074 6.93e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 6.93e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1773 EEVLKEKEKLE------ESYFVLQKEISQLaqtnshisaDLLEAQSENRTLRKDKSKLTLKIRELEtlhsftaaQTAEDA 1846
Cdd:COG1196   196 GELERQLEPLErqaekaERYRELKEELKEL---------EAELLLLKLRELEAELEELEAELEELE--------AELEEL 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1847 MQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQ 1926
Cdd:COG1196   259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1927 LSALQEENVKLAEELGRTRDEVTSHQK----LEEERSVLNNQLLEMKKRESEYRKDADEEKASLQKSISLTSALLTEKDA 2002
Cdd:COG1196   339 LEELEEELEEAEEELEEAEAELAEAEEalleAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672073054 2003 ELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDVQTEEDERAQ 2074
Cdd:COG1196   419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA 490
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
351-990 1.42e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.97  E-value: 1.42e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  351 ALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELalardghdQHVLELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:PRK02224  210 GLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERR--------EELETLEAEIEDLRETIAETEREREELAEEV 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  431 EEEKRKVEDLQfrvEEESITKGDLEQKSQISEDPEntqtklehARIKELEqsllfekTKADKLQRELEDTRV---ATVSE 507
Cdd:PRK02224  282 RDLRERLEELE---EERDDLLAEAGLDDADAEAVE--------ARREELE-------DRDEELRDRLEECRVaaqAHNEE 343

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  508 KSRIMELEKDLALRVQEVAELRRRLESskppgdvdmslsllqEISALQEKLEvthtDHQNEVTSLKDHFGTREEMFQKEI 587
Cdd:PRK02224  344 AESLREDADDLEERAEELREEAAELES---------------ELEEAREAVE----DRREEIEELEEEIEELRERFGDAP 404

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  588 KALhaatEKLSKENESLRSKLDHANKENSDVIALWKSkLETAIASHQQAMEELKVSfskgigtdsaefaelktqierlrl 667
Cdd:PRK02224  405 VDL----GNAEDFLEELREERDELREREAELEATLRT-ARERVEEAEALLEAGKCP------------------------ 455

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  668 dyqheiESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEDqhLVEMEEMLSKLQEAEIKVKELevl 747
Cdd:PRK02224  456 ------ECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAED--LVEAEDRIERLEERREDLEEL--- 524

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  748 qakyseqtqvvghLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEGAEKqiknlemernaESSKANSITKDLQGK 827
Cdd:PRK02224  525 -------------IAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEE-----------EAEEAREEVAELNSK 580

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  828 ELMLTSLQSNLNEVNQVKETLE---KELQTLKEK---FASASEEAVSTQTSMQDTVNKLHQK--EEQFNMLSSELEKLRE 899
Cdd:PRK02224  581 LAELKERIESLERIRTLLAAIAdaeDEIERLREKreaLAELNDERRERLAEKRERKRELEAEfdEARIEEAREDKERAEE 660

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  900 NLTDMEAKFKEKDEREDQLVKAKEKLENDIAEImkmsgdnssqltkmnDELRLKERSVEELQLKLTKANENASLLQKSIG 979
Cdd:PRK02224  661 YLEQVEEKLDELREERDDLQAEIGAVENELEEL---------------EELRERREALENRVEALEALYDEAEELESMYG 725

                         650
                  ....*....|.
gi 672073054  980 EvtLKAEQSQQ 990
Cdd:PRK02224  726 D--LRAELRQR 734
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1420-2056 1.45e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.04  E-value: 1.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1420 SERALLAEKEELLNENRVITEKLNKHSEEvtrlevslnekityLTSEKEMACQKVARLKKQQDSLLKEKSAleVQNGDLL 1499
Cdd:pfam05483   96 SIEAELKQKENKLQENRKIIEAQRKAIQE--------------LQFENEKVSLKLEEEIQENKDLIKENNA--TRHLCNL 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1500 ADRESSIKAIGDLKRKYEQEATNrrlavQEKVKLLGNIDALKKELQQRKKENQelaSSKCDLSLMLKEAQTAKKNLEKEH 1579
Cdd:pfam05483  160 LKETCARSAEKTKKYEYEREETR-----QVYMDLNNNIEKMILAFEELRVQAE---NARLEMHFKLKEDHEKIQHLEEEY 231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1580 TSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEECQklnEEIREIQQTLMLEKEARAKESESSLYESNKLHGRIVLLEEE 1659
Cdd:pfam05483  232 KKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESR---DKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRS 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1660 IQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEK------------------ELLSAETAQLAANIETLKSDFAALSK 1721
Cdd:pfam05483  309 MSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKaahsfvvtefeattcsleELLRTEQQRLEKNEDQLKIITMELQK 388

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1722 SKLELQELhscltkilDDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEV------------LKEKE--------- 1780
Cdd:pfam05483  389 KSSELEEM--------TKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELkgkeqelifllqAREKEihdleiqlt 460

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1781 --KLEESYFV-----LQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIR------------------ELETLH 1835
Cdd:pfam05483  461 aiKTSEEHYLkevedLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKkhqediinckkqeermlkQIENLE 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1836 SfTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIET 1915
Cdd:pfam05483  541 E-KEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKA 619

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1916 LKQAAAQKSQQLSALQEENVKLAEELGRTRDE----VTSHQKLEEERSVLNNQLLEmkkrESEYRKDADEEKASLQKSIS 1991
Cdd:pfam05483  620 LKKKGSAENKQLNAYEIKVNKLELELASAKQKfeeiIDNYQKEIEDKKISEEKLLE----EVEKAKAIADEAVKLQKEID 695

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672073054  1992 L-TSALLTEKDAELEKLRNEVTVLRGENASAKSLH-SVVQTLESDKVKLELKVKNLELQLKENKRQL 2056
Cdd:pfam05483  696 KrCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYkNKEQEQSSAKAALEIELSNIKAELLSLKKQL 762
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2171-2187 1.59e-07

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 49.00  E-value: 1.59e-07
                           10
                   ....*....|....*..
gi 672073054  2171 RPYCEICEMFGHWATNC 2187
Cdd:pfam16641    1 RPYCEICEVFGHDTEDC 17
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1494-1996 4.82e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.07  E-value: 4.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1494 QNGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKK 1573
Cdd:PRK03918  197 EKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIE 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1574 NLE-------------KEHTSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEECQKLNEEIREIQQTLMLEKEARAKESE 1640
Cdd:PRK03918  277 ELEekvkelkelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1641 ssLYESNKLHGRIVLLEEEIQGLRT-----CSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSD 1715
Cdd:PRK03918  357 --LEERHELYEEAKAKKEELERLKKrltglTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA 434

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1716 FAALSKSKLELQELHSclTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREM---------MLRNEEVLKEKEKLEESY 1786
Cdd:PRK03918  435 KGKCPVCGRELTEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRELekvlkkeseLIKLKELAEQLKELEEKL 512

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1787 FVLQKE-ISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLHSftAAQTAEDAMQIMEQMTKEK-------- 1857
Cdd:PRK03918  513 KKYNLEeLEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEK--KLDELEEELAELLKELEELgfesveel 590

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1858 TETLASLEDTKQTNAKL---QSELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQlsALQEEN 1934
Cdd:PRK03918  591 EERLKELEPFYNEYLELkdaEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYE--ELREEY 668

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672073054 1935 VKLAEELGRTRDEVTSHQKLEEERSvlnnQLLEMKKRESEYRKDADEEKASLQKSISLTSAL 1996
Cdd:PRK03918  669 LELSRELAGLRAELEELEKRREEIK----KTLEKLKEELEEREKAKKELEKLEKALERVEEL 726
PTZ00121 PTZ00121
MAEBL; Provisional
 1611-2105 5.04e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 5.04e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1611 QEECQKLNEEIREIQQTLMLEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQ--KV 1688
Cdd:PTZ00121 1117 AEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEElrKA 1196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1689 VEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREM 1768
Cdd:PTZ00121 1197 EDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEE 1276

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1769 MLRNEEVLK--EKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDA 1846
Cdd:PTZ00121 1277 ARKADELKKaeEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAA 1356

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1847 MQIMEQMTKEKTETLASLEDTKQTNA--------------KLQSELDTLKENNLKTVEELNKSKELLN---EENQKMEEF 1909
Cdd:PTZ00121 1357 DEAEAAEEKAEAAEKKKEEAKKKADAakkkaeekkkadeaKKKAEEDKKKADELKKAAAAKKKADEAKkkaEEKKKADEA 1436

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1910 KKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTshQKLEEERsvlnnQLLEMKKRESEYRKDADEEKASLQKS 1989
Cdd:PTZ00121 1437 KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK--KKAEEAK-----KADEAKKKAEEAKKKADEAKKAAEAK 1509

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1990 ISLTSALLTEKDAELEKLRNEVTVLRGENA-SAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDVQTE 2068
Cdd:PTZ00121 1510 KKADEAKKAEEAKKADEAKKAEEAKKADEAkKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA 1589

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 672073054 2069 EDERAQESQIDFLNSVIVDLQ--RKNQDLKMKVEMMSEA 2105
Cdd:PTZ00121 1590 EEARIEEVMKLYEEEKKMKAEeaKKAEEAKIKAEELKKA 1628
PRK11281 PRK11281
mechanosensitive channel MscK;
656-901 6.68e-07

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 54.92  E-value: 6.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  656 AELKTQIERLRLDYQHEIESLQSKQDSERS--------AHAKEMESMKAKLM---KIIKEKEDSLEAVKARLDTAEDQH- 723
Cdd:PRK11281   39 ADVQAQLDALNKQKLLEAEDKLVQQDLEQTlalldkidRQKEETEQLKQQLAqapAKLRQAQAELEALKDDNDEETRETl 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  724 ----LVEMEEMLSKLQEaeikvkELEVLQAKYSE-QTQVVGHLT------SQLSVVEEQLLDLDALRKANSEGKLEIETL 792
Cdd:PRK11281  119 stlsLRQLESRLAQTLD------QLQNAQNDLAEyNSQLVSLQTqperaqAALYANSQRLQQIRNLLKGGKVGGKALRPS 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  793 RQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLnevnqvketLEKELQTLKE----KFASASEEAVS 868
Cdd:PRK11281  193 QRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQR---------LEHQLQLLQEainsKRLTLSEKTVQ 263

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 672073054  869 TQTSMQDTV----NKLHQKEEQFNM-LSSELEKLRENL 901
Cdd:PRK11281  264 EAQSQDEAAriqaNPLVAQELEINLqLSQRLLKATEKL 301
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1427-2059 6.94e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 6.94e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1427 EKEELLNENRVITEKLNKHSEEVTRLEVSLNEKITYLTSEKEmacqKVARLKKQQDSLlkeKSALEVQNGDLLADRESSI 1506
Cdd:TIGR04523   34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNN----KIKILEQQIKDL---NDKLKKNKDKINKLNSDLS 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1507 KAIGDLKRKYEQeatnrrlavqeKVKLLGNIDALKKELQQRKKEnqelasskcdlslmLKEAQTAKKNLEKEHTSMMQAK 1586
Cdd:TIGR04523  107 KINSEIKNDKEQ-----------KNKLEVELNKLEKQKKENKKN--------------IDKFLTEIKKKEKELEKLNNKY 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1587 EDLNAELKTCCCEKNILLRDGLNLQEECQKLNEEIREIQQTLML--EKEARAKESESSLYE----SNKLHGRIVLLEEEI 1660
Cdd:TIGR04523  162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNlkKKIQKNKSLESQISElkkqNNQLKDNIEKKQQEI 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1661 QGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLE--LQELHSCLTKILD 1738
Cdd:TIGR04523  242 NEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdwNKELKSELKNQEK 321

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1739 DLRlnhevavTERAEVLQDNKNLlaekremmlrneevlkekEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLR 1818
Cdd:TIGR04523  322 KLE-------EIQNQISQNNKII------------------SQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLK 376

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1819 KDKS-------KLTLKIRELETLHSFTAAQTAEDAMQImEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEE 1891
Cdd:TIGR04523  377 KENQsykqeikNLESQINDLESKIQNQEKLNQQKDEQI-KKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELI 455

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1892 LNKSKELLNEENQKMEEFKKEIETLKQAA-------AQKSQQLSALQEENVKLAEELGRTRDEVTS----HQKLEEERSV 1960
Cdd:TIGR04523  456 IKNLDNTRESLETQLKVLSRSINKIKQNLeqkqkelKSKEKELKKLNEEKKELEEKVKDLTKKISSlkekIEKLESEKKE 535

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1961 LNNQLLEMKKRESEyrKDADEEKASLQKSISltsalltEKDAELEKLRNEVTVLRGENASAKSLhsvVQTLESDKVKLEL 2040
Cdd:TIGR04523  536 KESKISDLEDELNK--DDFELKKENLEKEID-------EKNKEIEELKQTQKSLKKKQEEKQEL---IDQKEKEKKDLIK 603

                          650
                   ....*....|....*....
gi 672073054  2041 KVKNLELQLKENKRQLSSS 2059
Cdd:TIGR04523  604 EIEEKEKKISSLEKELEKA 622
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 788-993 1.08e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 1.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  788 EIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAV 867
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  868 STQTSMQDTVNKLHQKEEQ------------------FNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDI 929
Cdd:COG4942   101 AQKEELAELLRALYRLGRQpplalllspedfldavrrLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672073054  930 AEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASLLQKSIGEVTLKAEQSQQEAA 993
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 404-1629 1.37e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 53.90  E-value: 1.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   404 ELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRV------------EEESITKGDLEQKSQ---ISEDPENTQ 468
Cdd:TIGR01612  541 EIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIkdlfdkyleiddEIIYINKLKLELKEKiknISDKNEYIK 620

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   469 TKLEHARIKELEQSLLFEKTKADKLQ----RELEDTRVATV-SEKSRIME-----LEKDLALRVQEVA----ELRRRLES 534
Cdd:TIGR01612  621 KAIDLKKIIENNNAYIDELAKISPYQvpehLKNKDKIYSTIkSELSKIYEddidaLYNELSSIVKENAidntEDKAKLDD 700

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   535 SKppGDVDMSLSLLQEISAlqEKLEVTHTDHQNEVTSLKDHFGTREEMFQKEI-KALHAATEKLSKENESLRSKLDHANK 613
Cdd:TIGR01612  701 LK--SKIDKEYDKIQNMET--ATVELHLSNIENKKNELLDIIVEIKKHIHGEInKDLNKILEDFKNKEKELSNKINDYAK 776

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   614 ENsDVIALWKSKLetaiashqqamEELKVSFSKGIGTDSAEFAELKTQIERLRldyqHEIESLQSKQDsERSAHAKEMES 693
Cdd:TIGR01612  777 EK-DELNKYKSKI-----------SEIKNHYNDQINIDNIKDEDAKQNYDKSK----EYIKTISIKED-EIFKIINEMKF 839

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   694 MKAKLMKIIKEKEDSLEAVKARLDTAEDQhlveMEEMLSKLQeAEIKVKELEVLQAKYSEQTQVVGHLTSQlsvVEEQLL 773
Cdd:TIGR01612  840 MKDDFLNKVDKFINFENNCKEKIDSEHEQ----FAELTNKIK-AEISDDKLNDYEKKFNDSKSLINEINKS---IEEEYQ 911

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   774 DLDALRKANSEGKL------EIETLR-QQLEGAEKQIKNLEMERNA---ESSKANSITKDLQGK---------ELMLTSL 834
Cdd:TIGR01612  912 NINTLKKVDEYIKIcentkeSIEKFHnKQNILKEILNKNIDTIKESnliEKSYKDKFDNTLIDKineldkafkDASLNDY 991

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   835 QSNLNEVNQVKETLEKELQTLKEKFasaseeavstqtsmqdTVNKLHQKEEQFNMLSSELEKLRENLTDME-----AKFK 909
Cdd:TIGR01612  992 EAKNNELIKYFNDLKANLGKNKENM----------------LYHQFDEKEKATNDIEQKIEDANKNIPNIEiaihtSIYN 1055

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   910 EKDEREDQLVKAKEKLENdiaEIMKMSGDNSSQLTKMNDELRLKERS--VEELQLKLTkanENASLLQKSIGEVTLKAEQ 987
Cdd:TIGR01612 1056 IIDEIEKEIGKNIELLNK---EILEEAEINITNFNEIKEKLKHYNFDdfGKEENIKYA---DEINKIKDDIKNLDQKIDH 1129

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   988 SQQEaakkheeeKKELENKLLELEKKMETshyQCQDLKAKYEKASSETKIkhEEILQNFQKMLVDTEDKLKAAQEANRDL 1067
Cdd:TIGR01612 1130 HIKA--------LEEIKKKSENYIDEIKA---QINDLEDVADKAISNDDP--EEIEKKIENIVTKIDKKKNIYDEIKKLL 1196

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1068 --MQDMEELKSQADKAK--SLTYLLTSAKKEIEVMSEELRglKSEKQLFAQEASALKLEKGSLLSKLIEVETKITLlqed 1143
Cdd:TIGR01612 1197 neIAEIEKDKTSLEEVKgiNLSYGKNLGKLFLEKIDEEKK--KSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEM---- 1270

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1144 qqklwsvNENLHLEKERISEEKQvaEKRYQQEHRDKESLVVEREKLLK---------EINVTQEELLK------MHMEKD 1208
Cdd:TIGR01612 1271 -------DIKAEMETFNISHDDD--KDHHIISKKHDENISDIREKSLKiiedfseesDINDIKKELQKnlldaqKHNSDI 1341

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1209 SLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKDDVIQKLQSAYEELVKDQKALVQEI 1288
Cdd:TIGR01612 1342 NLYLNEIANIYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKDIDECI 1421

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1289 EDLTTEKKSAAEKQMNLDNTCLTLKAEREN--LLQSNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLST--EAETLRTQ 1364
Cdd:TIGR01612 1422 KKIKELKNHILSEESNIDTYFKNADENNENvlLLFKNIEMADNKSQHILKIKKDNATNDHDFNINELKEHidKSKGCKDE 1501

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1365 LDCATKALRKAELDMRQLQTSNTS-LTKLLE-EIKTCRAITDSECIQLLHEKESlAASERALLAEKEEllnenrvitEKL 1442
Cdd:TIGR01612 1502 ADKNAKAIEKNKELFEQYKKDVTElLNKYSAlAIKNKFAKTKKDSEIIIKEIKD-AHKKFILEAEKSE---------QKI 1571

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1443 NKHSEEVTRLE--VSLNEK-------ITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLAD-RESSIKAIGDL 1512
Cdd:TIGR01612 1572 KEIKKEKFRIEddAAKNDKsnkaaidIQLSLENFENKFLKISDIKKKINDCLKETESIEKKISSFSIDsQDTELKENGDN 1651

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1513 K---RKYEQEATNRRLAVQEKVKLLGNIDA----LKKELQQRKKeNQELAsskcdlsLMLKEAQTAKKNLEKehtsMMQA 1585
Cdd:TIGR01612 1652 LnslQEFLESLKDQKKNIEDKKKELDELDSeiekIEIDVDQHKK-NYEIG-------IIEKIKEIAIANKEE----IESI 1719

                         1290      1300      1310      1320
                   ....*....|....*....|....*....|....*....|....
gi 672073054  1586 KEDLNAELKTCCCEKNILLRDGLNLQEECQKLNEEIREIQQTLM 1629
Cdd:TIGR01612 1720 KELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFI 1763
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1112-1796 1.88e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.43  E-value: 1.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1112 FAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLK 1191
Cdd:TIGR00618  154 FAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLRE 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1192 EINVTQEELLKMHMEKDSLEASKVSMQVLIEELRFCKDklmAMSEKARAEKEQLEGQVKKLTAENMVLVKDKDDVIQKLQ 1271
Cdd:TIGR00618  234 ALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEE---LRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQ 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1272 SAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQF-----EKDTLRQGQEKLSASLEA 1346
Cdd:TIGR00618  311 RIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIreiscQQHTLTQHIHTLQQQKTT 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1347 TLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERALLA 1426
Cdd:TIGR00618  391 LTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1427 EKEELLNENRVITEKLNKHSEEVTRLEVSLNEKITYLTSEKEMACQKVA---------RLKKQQDSLLKEKSALEVQNGD 1497
Cdd:TIGR00618  471 REQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDidnpgpltrRMQRGEQTYAQLETSEEDVYHQ 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1498 LLADRE--SSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDAL--------------KKELQQRKKENQELASSKCDL 1561
Cdd:TIGR00618  551 LTSERKqrASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRlqdlteklseaedmLACEQHALLRKLQPEQDLQDV 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1562 SLML----KEAQTAKKNLEKEHTSMMQAKEDLNA----ELKTCCCEKNILLRDGLNLQEECQKLNEEIREIQQTLMLEKE 1633
Cdd:TIGR00618  631 RLHLqqcsQELALKLTALHALQLTLTQERVREHAlsirVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1634 ARAKESESSLYE-SNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETL 1712
Cdd:TIGR00618  711 THIEEYDREFNEiENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFF 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1713 KSDFAALSKS-KLELQELHSCLTKILDDLRLNHEVAVTERAEV---LQDNKNLLAEKREMMLRNEEVLKEKEKLEESyfv 1788
Cdd:TIGR00618  791 NRLREEDTHLlKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFlsrLEEKSATLGEITHQLLKYEECSKQLAQLTQE--- 867


                   ....*...
gi 672073054  1789 lQKEISQL 1796
Cdd:TIGR00618  868 -QAKIIQL 874
PRK11281 PRK11281
mechanosensitive channel MscK;
1870-2095 2.21e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 52.99  E-value: 2.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1870 TNAKLQSELDTLKENNLKTVEE------LNKSKELLneenQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELG- 1942
Cdd:PRK11281   37 TEADVQAQLDALNKQKLLEAEDklvqqdLEQTLALL----DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDe 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1943 --RTRDEVTSHQKLEEERSVLNNQLLEMKKRESEYrkdaDEEKASLQKSISLTSALLTEKDAELEKLRNEvtvLRGENAS 2020
Cdd:PRK11281  113 etRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEY----NSQLVSLQTQPERAQAALYANSQRLQQIRNL---LKGGKVG 185

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 672073054 2021 AKSLHSvvqtleSDKVKLELKVKNLELQLKENKRQLsssSGNTDVQTEEderaqESQIDFLNSVIVDLQRKNQDL 2095
Cdd:PRK11281  186 GKALRP------SQRVLLQAEQALLNAQNDLQRKSL---EGNTQLQDLL-----QKQRDYLTARIQRLEHQLQLL 246
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1330-1917 2.60e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.76  E-value: 2.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1330 KDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLdcatKALRKAELDMRQLQTSNTSLTKLLEEIKTCRAITDSECIQ 1409
Cdd:PRK03918  171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVL----REINEISSELPELREELEKLEKEVKELEELKEEIEELEKE 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1410 LLHEKESLAASErALLAEKEELLNENRVITEKLNKHSEEVTRLEVSLNEKITyLTSEKEMACQKVARLKKQQDSLLKEKS 1489
Cdd:PRK03918  247 LESLEGSKRKLE-EKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK-LSEFYEEYLDELREIEKRLSRLEEEIN 324

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1490 ALEVQngdlLADRESSIKAIGDLKRKyEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKENQELasSKCDLSLMLKEAQ 1569
Cdd:PRK03918  325 GIEER----IKELEEKEERLEELKKK-LKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGL--TPEKLEKELEELE 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1570 TAKKNLEKEHTSMMQAKEDLN---AELKTCCCE----KNILLRDGLNLQEECQK--LNEEIREIQQtlMLEKEARAKESE 1640
Cdd:PRK03918  398 KAKEEIEEEISKITARIGELKkeiKELKKAIEElkkaKGKCPVCGRELTEEHRKelLEEYTAELKR--IEKELKEIEEKE 475

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1641 SSLYESNKLHGRIVLLEEEIQGLRTCSEQLqtENFTLTQEKTNSEqKVVEIIKEKELLSAETAQLAANIETLKSDFAALS 1720
Cdd:PRK03918  476 RKLRKELRELEKVLKKESELIKLKELAEQL--KELEEKLKKYNLE-ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE 552

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1721 KSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEEsyfvLQKEISQLAQTN 1800
Cdd:PRK03918  553 ELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELER----EEKELKKLEEEL 628

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1801 SHISADLLEAQSENRTLRKdkskltlKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSELdt 1880
Cdd:PRK03918  629 DKAFEELAETEKRLEELRK-------ELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL-- 699

                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 672073054 1881 lkENNLKTVEELNKSKELLNEENQKMEEFKKEIETLK 1917
Cdd:PRK03918  700 --KEELEEREKAKKELEKLEKALERVEELREKVKKYK 734
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
648-1170 2.97e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 52.76  E-value: 2.97e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  648 IGTDSAEFAELKTQIERLRldyqHEIESLQSKQDsERSAHAKEMESMKAKLMKIIKEK---EDSLEAVKARLDTAEDQ-- 722
Cdd:PRK03918  195 IKEKEKELEEVLREINEIS----SELPELREELE-KLEKEVKELEELKEEIEELEKELeslEGSKRKLEEKIRELEERie 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  723 ----HLVEMEEMLSKLQEAEIKVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEG 798
Cdd:PRK03918  270 elkkEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKE 349

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  799 AEKQIKNLEmERNAESSKANSITKDLQG-----KELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSM 873
Cdd:PRK03918  350 LEKRLEELE-ERHELYEEAKAKKEELERlkkrlTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAI 428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  874 QD---------TVNKLHQKEEQFNMlsseLEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMsgdnsSQLT 944
Cdd:PRK03918  429 EElkkakgkcpVCGRELTEEHRKEL----LEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEL-----IKLK 499

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  945 KMNDELRLKERSVEELQL-KLTKANENASLLQKSIGEvtLKAEQSQQEAAKKHEEEKKELENKLLELEKKMETShyqcqd 1023
Cdd:PRK03918  500 ELAEQLKELEEKLKKYNLeELEKKAEEYEKLKEKLIK--LKGEIKSLKKELEKLEELKKKLAELEKKLDELEEE------ 571

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1024 lKAKYEKASSETKIKHEEILQNFQKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKAKSLTYLLTSAKKEIEVMSEELR 1103
Cdd:PRK03918  572 -LAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE 650

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 672073054 1104 GLKSEkqlFAQEASALKLEKGSLLSKLIE-VETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEK 1170
Cdd:PRK03918  651 ELEKK---YSEEEYEELREEYLELSRELAgLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEK 715
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 595-991 2.99e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 2.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   595 EKLSKENESLRSKLDHANKENSdvialwksKLETAIASHQQAMEELKvsfskgigtdsAEFAELKTQIERLRLDYQHEIE 674
Cdd:TIGR04523  207 KKKIQKNKSLESQISELKKQNN--------QLKDNIEKKQQEINEKT-----------TEISNTQTQLNQLKDEQNKIKK 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   675 SLQSKQdsersahaKEMESMKAKlmkiIKEKEDSLEAVKARLDTAEDQHlvemEEMLSKLQEAEIKVKE--LEVLQAKYS 752
Cdd:TIGR04523  268 QLSEKQ--------KELEQNNKK----IKELEKQLNQLKSEISDLNNQK----EQDWNKELKSELKNQEkkLEEIQNQIS 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   753 EQTQVVGHLTSQLSVVEEQLLDLDA----LRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKE 828
Cdd:TIGR04523  332 QNNKIISQLNEQISQLKKELTNSESenseKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKD 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   829 LMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKF 908
Cdd:TIGR04523  412 EQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   909 KEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANEN--ASLLQKSIGEVTLKAE 986
Cdd:TIGR04523  492 KSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFElkKENLEKEIDEKNKEIE 571


                   ....*
gi 672073054   987 QSQQE 991
Cdd:TIGR04523  572 ELKQT 576
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 761-972 4.11e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 4.11e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  761 LTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEGAEKQIKNLEmernaesSKANSITKDLQGKELMLTSLQSNLNE 840
Cdd:COG4942    15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALE-------RRIAALARRIRALEQELAALEAELAE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  841 VNQVKETLEKELQTLKEKFA-----------SASEEAVSTQTSMQDTVNKLH-------QKEEQFNMLSSELEKLRENLT 902
Cdd:COG4942    88 LEKEIAELRAELEAQKEELAellralyrlgrQPPLALLLSPEDFLDAVRRLQylkylapARREQAEELRADLAELAALRA 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  903 DMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENAS 972
Cdd:COG4942   168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
711-927 5.75e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.84  E-value: 5.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  711 AVKARLDTAEDQ--HLVEMEEMLSKLQEaeiKVKELEVLQAKYSEQTQvvghLTSQLSVVEEQL--LDLDALRKANSEGK 786
Cdd:COG4913   222 DTFEAADALVEHfdDLERAHEALEDARE---QIELLEPIRELAERYAA----ARERLAELEYLRaaLRLWFAQRRLELLE 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  787 LEIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQ---GKELmlTSLQSNLNEVNQVKETLEKELQTLKEKFASAS 863
Cdd:COG4913   295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRgngGDRL--EQLEREIERLERELEERERRRARLEALLAALG 372

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 672073054  864 EEAVSTQTSMQDTVNKLHQKEEQfnmLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLEN 927
Cdd:COG4913   373 LPLPASAEEFAALRAEAAALLEA---LEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
354-951 6.87e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 6.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  354 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALAR-DGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEE 432
Cdd:COG4913   255 EPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRG 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  433 EK-RKVEDLQFRVEEEsitKGDLEQKSQISEDPENTQTKLEHARIKELEQsllFEKTKA------DKLQRELEDTRVATV 505
Cdd:COG4913   335 NGgDRLEQLEREIERL---ERELEERERRRARLEALLAALGLPLPASAEE---FAALRAeaaallEALEEELEALEEALA 408

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  506 SEKSRIMELEKDLALRVQEVAELRRRlESSKPPGDVDMSLSLLQEISALQEKL-------EVthtdhqnevtslkdhfGT 578
Cdd:COG4913   409 EAEAALRDLRRELRELEAEIASLERR-KSNIPARLLALRDALAEALGLDEAELpfvgeliEV----------------RP 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  579 REEMFQKEI-KALH--------------AATEKLskENESLRSKLDhankenSDVIALWKSKLETAIASHQQAMEELKVS 643
Cdd:COG4913   472 EEERWRGAIeRVLGgfaltllvppehyaAALRWV--NRLHLRGRLV------YERVRTGLPDPERPRLDPDSLAGKLDFK 543

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  644 fskgigtDSAEFAELKTQIERlRLDYqHEIESLQSKQDSERS------------AHAKEMESMKAKLMKIIKEKEDSLEA 711
Cdd:COG4913   544 -------PHPFRAWLEAELGR-RFDY-VCVDSPEELRRHPRAitragqvkgngtRHEKDDRRRIRSRYVLGFDNRAKLAA 614

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  712 VKARLDTAEDQhLVEMEEMLSKLQEaeikvkELEVLQAKYSEQTQVVGHLTSQLSV--VEEQLLDLDALRKANSEGKLEI 789
Cdd:COG4913   615 LEAELAELEEE-LAEAEERLEALEA------ELDALQERREALQRLAEYSWDEIDVasAEREIAELEAELERLDASSDDL 687

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  790 ETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELqtLKEKFASASEEAV-- 867
Cdd:COG4913   688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAL--LEERFAAALGDAVer 765

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  868 ----STQTSMQDTVNKLHQKEEQ-----------FNMLSSE--------------LEKLREN-LTDMEAKFKE-KDERED 916
Cdd:COG4913   766 elreNLEERIDALRARLNRAEEEleramrafnreWPAETADldadleslpeylalLDRLEEDgLPEYEERFKElLNENSI 845

                         650       660       670
                  ....*....|....*....|....*....|....*.
gi 672073054  917 QLVKA-KEKLENDIAEImkmsgdnSSQLTKMNDELR 951
Cdd:COG4913   846 EFVADlLSKLRRAIREI-------KERIDPLNDSLK 874
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1533-2112 7.42e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 7.42e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1533 LLGNIDALKKELQQRKKENQElasskcDLSLMLKEAQTAKKNLEKEHTSMMqakedlnaelkTCCCEKNILLRDGLN-LQ 1611
Cdd:pfam15921  236 LKGRIFPVEDQLEALKSESQN------KIELLLQQHQDRIEQLISEHEVEI-----------TGLTEKASSARSQANsIQ 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1612 EECQKLNEEIREIQQTLML---EKEARAKESESSLYESNKLHgrivllEEEIQGLRtcsEQLQTENFTLTQEKTnseqkv 1688
Cdd:pfam15921  299 SQLEIIQEQARNQNSMYMRqlsDLESTVSQLRSELREAKRMY------EDKIEELE---KQLVLANSELTEART------ 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1689 veiikEKELLSAETAQLAANIETLKSDfaaLSKSKLELQeLHSCLTKILDDLRLNHEVAVTERAEVLqDNKNLLAEKREM 1768
Cdd:pfam15921  364 -----ERDQFSQESGNLDDQLQKLLAD---LHKREKELS-LEKEQNKRLWDRDTGNSITIDHLRREL-DDRNMEVQRLEA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1769 MLRNEEVlKEKEKLEESYFVLQKEISQLAQTNShISADLleaQSENRTLRKDKSKLTLKIRELETLHSFTAAQTA--EDA 1846
Cdd:pfam15921  434 LLKAMKS-ECQGQMERQMAAIQGKNESLEKVSS-LTAQL---ESTKEMLRKVVEELTAKKMTLESSERTVSDLTAslQEK 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1847 MQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKenNLKTveELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQ 1926
Cdd:pfam15921  509 ERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLR--NVQT--ECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1927 LSALQEENVKLAEELGRTRDEVTSHQKLEEERsvlnnqllEMKKRESEYR-KDADEEKASLQKSISLTSALLTEKDAELE 2005
Cdd:pfam15921  585 AGAMQVEKAQLEKEINDRRLELQEFKILKDKK--------DAKIRELEARvSDLELEKVKLVNAGSERLRAVKDIKQERD 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  2006 KLRNEVTVLRGE-NASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDVQTEEDERAQESQIDfLNSV 2084
Cdd:pfam15921  657 QLLNEVKTSRNElNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMG-MQKQ 735

                          570       580
                   ....*....|....*....|....*...
gi 672073054  2085 IVDLQRKNQDLKMKVEMMSEAALNGNGE 2112
Cdd:pfam15921  736 ITAKRGQIDALQSKIQFLEEAMTNANKE 763
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
846-1375 7.47e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 7.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  846 ETLEkELQTLKEKFASASEEAvSTQTSMQDTVNkLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKL 925
Cdd:COG4913   252 ELLE-PIRELAERYAAARERL-AELEYLRAALR-LWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEL 328

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  926 ENDIAEImkmSGDNSSQLtkmndelrlkERSVEELQLKLTKANENASLLQKSIGEVTLKAEQSQQEAAKKHEEEKKELEN 1005
Cdd:COG4913   329 EAQIRGN---GGDRLEQL----------EREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEA 395

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1006 KLLELEKKMETSHyqcqDLKAKYEKASSETKIKHEEIL----------QNFQKMLVDTEDKLKAAQEANR---DLMQDME 1072
Cdd:COG4913   396 LEEELEALEEALA----EAEAALRDLRRELRELEAEIAslerrksnipARLLALRDALAEALGLDEAELPfvgELIEVRP 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1073 E-----------LKSQAdkakslTYLLTSAKKEIEVmSEELRGLKSEKQL-------FAQEASALKLEKGSLLSKLIEVE 1134
Cdd:COG4913   472 EeerwrgaiervLGGFA------LTLLVPPEHYAAA-LRWVNRLHLRGRLvyervrtGLPDPERPRLDPDSLAGKLDFKP 544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1135 TKIT--LLQE--DQQKLWSVN--ENLHLEKERISEEKQVAEKRYQQEHRDK-----------------ESLVVEREKLLK 1191
Cdd:COG4913   545 HPFRawLEAElgRRFDYVCVDspEELRRHPRAITRAGQVKGNGTRHEKDDRrrirsryvlgfdnraklAALEAELAELEE 624

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1192 EINVTQEELLKMHMEKDSLEASKVSMQVLiEELRFCKDKLMAmsekARAEKEQLEGQVKKLTAENmvlvkdkdDVIQKLQ 1271
Cdd:COG4913   625 ELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVAS----AEREIAELEAELERLDASS--------DDLAALE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1272 SAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLSASLEatlQVK 1351
Cdd:COG4913   692 EQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVER---ELR 768

                         570       580
                  ....*....|....*....|....
gi 672073054 1352 QLLSTEAETLRTQLDCATKALRKA 1375
Cdd:COG4913   769 ENLEERIDALRARLNRAEEELERA 792
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 779-1536 8.25e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.12  E-value: 8.25e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   779 RKANSEGKLEIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSlqsnlnevnqVKETLEKELQTLKEk 858
Cdd:TIGR00618  165 KKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHE----------RKQVLEKELKHLRE- 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   859 fasaseeavsTQTSMQDTVNKLHQKEEQFNmlssELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLEND-----IAEIM 933
Cdd:TIGR00618  234 ----------ALQQTQQSHAYLTQKREAQE----EQLKKQQLLKQLRARIEELRAQEAVLEETQERINRArkaapLAAHI 299

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   934 KMSGDNSSQLTKMNDELRLKERSVE-ELQLKLTKANENASLLQKSIGEVTLKAEQSQQEAAKKHEEEKKELENKLLELEK 1012
Cdd:TIGR00618  300 KAVTQIEQQAQRIHTELQSKMRSRAkLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQ 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1013 KMETSHYQCQDLKAKYEKASSETKIKHEEI-LQNFQKMLVDTEDKLKAAQEANRDLMQDMEELKSQAdkaksLTYLLTSA 1091
Cdd:TIGR00618  380 HIHTLQQQKTTLTQKLQSLCKELDILQREQaTIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAA-----ITCTAQCE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1092 KKEIEVMSEELRGLKSEKQLFAQEASALKLEKgsllSKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEK------ 1165
Cdd:TIGR00618  455 KLEKIHLQESAQSLKEREQQLQTKEQIHLQET----RKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGpltrrm 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1166 QVAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKMHMEKDSL----EASKVSMQVLIEELRFCKDKLMAMSEKARAE 1241
Cdd:TIGR00618  531 QRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILtqcdNRSKEDIPNLQNITVRLQDLTEKLSEAEDML 610

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1242 KEQLEGQVKKLTAEnmvlvKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDNtcLTLKAERENLLQ 1321
Cdd:TIGR00618  611 ACEQHALLRKLQPE-----QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLP--KELLASRQLALQ 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1322 S----NRDLQFEKDTLRQGQEKLSASLEATL-------QVKQLLSTEAETLRTQLDCATKALRKAELDMR---QLQTSNT 1387
Cdd:TIGR00618  684 KmqseKEQLTYWKEMLAQCQTLLRELETHIEeydrefnEIENASSSLGSDLAAREDALNQSLKELMHQARtvlKARTEAH 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1388 SLTKLLEEIKTCRAITDSECIQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRLEV----SLNEKITYL 1463
Cdd:TIGR00618  764 FNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEeqflSRLEEKSAT 843

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672073054  1464 TSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEAT---NRRLAVQEKVKLLGN 1536
Cdd:TIGR00618  844 LGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITlyaNVRLANQSEGRFHGR 919
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1750-1977 8.25e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 8.25e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1750 ERAEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIR 1829
Cdd:COG4942    28 ELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1830 ELetlhsftaaqtaEDAMQIMEQMTKEKteTLASLEDTKQTNAKLQSeLDTLKENNLKTVEELNKSKELLNEENQKMEEF 1909
Cdd:COG4942   108 EL------------LRALYRLGRQPPLA--LLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAELEAE 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 672073054 1910 KKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSH-QKLEEERSVLNNQLLEMKKRESEYRK 1977
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAElAELQQEAEELEALIARLEAEAAAAAE 241
PRK11281 PRK11281
mechanosensitive channel MscK;
708-993 8.61e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 51.07  E-value: 8.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  708 SLEAVKARLDTAEDQhlvemeemlsKLQEAEIKVkelevlqakyseqtqVVGHLtsqlsvvEEQLLDLDALRKAnsegKL 787
Cdd:PRK11281   37 TEADVQAQLDALNKQ----------KLLEAEDKL---------------VQQDL-------EQTLALLDKIDRQ----KE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  788 EIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKeLMLTSLQSNLNEVNQvketlekELQTLKEKFASASEEAV 867
Cdd:PRK11281   81 ETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLST-LSLRQLESRLAQTLD-------QLQNAQNDLAEYNSQLV 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  868 STQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLEndiaeimKMSGDNSSQLTkmn 947
Cdd:PRK11281  153 SLQTQPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQ-------RKSLEGNTQLQ--- 222

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 672073054  948 dELRLKERsvEELQLKLTKANENASLLQKSIG-------EVTLKAEQSQQEAA 993
Cdd:PRK11281  223 -DLLQKQR--DYLTARIQRLEHQLQLLQEAINskrltlsEKTVQEAQSQDEAA 272
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1833-2058 8.93e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 8.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1833 TLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKEnnlktveELNKSKELLNEENQKMEEFKKE 1912
Cdd:COG4942    12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER-------RIAALARRIRALEQELAALEAE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1913 IETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEYRKDADEEKASLQKSISL 1992
Cdd:COG4942    85 LAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672073054 1993 TSALLTEKDAELEKLRNEVTVLRGENASAKSLH-SVVQTLESDKVKLELKVKNLELQLKENKRQLSS 2058
Cdd:COG4942   165 LRAELEAERAELEALLAELEEERAALEALKAERqKLLARLEKELAELAAELAELQQEAEELEALIAR 231
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
337-738 9.00e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 9.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  337 ETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHD----------QHVLELE 406
Cdd:PRK02224  241 EVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGlddadaeaveARREELE 320

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  407 AKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKSQIS----EDPENTQTKLEhARIKELEQS 482
Cdd:PRK02224  321 DRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAreavEDRREEIEELE-EEIEELRER 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  483 LLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESSKPP------------GDVDMSLSLLQE 550
Cdd:PRK02224  400 FGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPecgqpvegsphvETIEEDRERVEE 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  551 ISALQEKLEVTHTDHQNEVTSLKDHFGTREEMFQKEIKAlHAATEKLSKENESL---RSKLDHANKENSDVIALWKSKLE 627
Cdd:PRK02224  480 LEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERR-EDLEELIAERRETIeekRERAEELRERAAELEAEAEEKRE 558

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  628 TAIASHQQAMEELKVsfskgIGTDSAEFAELKTQIERL---------RLDYQHEIESLQSK------QDSERSAHAKEME 692
Cdd:PRK02224  559 AAAEAEEEAEEAREE-----VAELNSKLAELKERIESLerirtllaaIADAEDEIERLREKrealaeLNDERRERLAEKR 633

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 672073054  693 SMKAKLMKiiKEKEDSLEAVKARLDTAEdQHLVEMEEMLSKLQEAE 738
Cdd:PRK02224  634 ERKRELEA--EFDEARIEEAREDKERAE-EYLEQVEEKLDELREER 676
PTZ00121 PTZ00121
MAEBL; Provisional
 892-1696 9.39e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 9.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  892 SELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENdIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENA 971
Cdd:PTZ00121 1106 TETGKAEEARKAEEAKKKAEDARKAEEARKAEDARK-AEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKA 1184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  972 SLLQKSigEVTLKAEQSQQEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEILQNFQKMLV 1051
Cdd:PTZ00121 1185 EEVRKA--EELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARM 1262

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1052 DTEDKLKAAQEANRdlMQDMEELKSQADKAKSltyllTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLE---KGSLLS 1128
Cdd:PTZ00121 1263 AHFARRQAAIKAEE--ARKADELKKAEEKKKA-----DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEakkKADAAK 1335

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1129 KLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLK---EINVTQEELLKMHM 1205
Cdd:PTZ00121 1336 KKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKkaeEDKKKADELKKAAA 1415

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1206 EKDSLEASKVSMqvliEELRFCKDKLMAMSEKARAEKEQLEGQVKKlTAENMVLVKDKDDVIQKLQSAYEELVK--DQKA 1283
Cdd:PTZ00121 1416 AKKKADEAKKKA----EEKKKADEAKKKAEEAKKADEAKKKAEEAK-KAEEAKKKAEEAKKADEAKKKAEEAKKadEAKK 1490

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1284 LVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQfEKDTLRQGQEKLSAslEATLQVKQLLSTE----AE 1359
Cdd:PTZ00121 1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK-KADEAKKAEEKKKA--DELKKAEELKKAEekkkAE 1567

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1360 TLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRAitdseciqllheKESLAASERALLAEKEELLNENRVIT 1439
Cdd:PTZ00121 1568 EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA------------EEAKKAEEAKIKAEELKKAEEEKKKV 1635

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1440 EKLNKHSEEVTRLEVSLNEKITYLTSEKEMACQKVARLKKQQDSLLKEKSAlEVQNGDLLADRESSIKAIGDLKRKYEQE 1519
Cdd:PTZ00121 1636 EQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEED-EKKAAEALKKEAEEAKKAEELKKKEAEE 1714

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1520 ATN-RRLAVQEKVKLLGNIDALKKELQQRKK--ENQELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELKTC 1596
Cdd:PTZ00121 1715 KKKaEELKKAEEENKIKAEEAKKEAEEDKKKaeEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRM 1794

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1597 CCEKNI--LLRDGLNLQEECQKLNEEIREIQQTLMLEKEARAKESESSLYESNKlhgrivlLEEEIQGLRTCSEQLQTEN 1674
Cdd:PTZ00121 1795 EVDKKIkdIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADA-------FEKHKFNKNNENGEDGNKE 1867

                         810       820
                  ....*....|....*....|..
gi 672073054 1675 FTLTQEKTNSEQKVVEIIKEKE 1696
Cdd:PTZ00121 1868 ADFNKEKDLKEDDEEEIEEADE 1889
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 334-975 9.86e-06

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 50.88  E-value: 9.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   334 LLTETSSRYARKISGTTALQEALKEKQQHIEQLLaERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDqlr 413
Cdd:pfam05483  159 LLKETCARSAEKTKKYEYEREETRQVYMDLNNNI-EKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKE--- 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   414 tmVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEQKsqisedpentqTKLEHARIKELEQsllfektKADKL 493
Cdd:pfam05483  235 --INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEK-----------TKLQDENLKELIE-------KKDHL 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   494 QRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESSkppgdvdmslslLQEISALQEKLEVTHTDHQNEVTSLK 573
Cdd:pfam05483  295 TKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQ------------MEELNKAKAAHSFVVTEFEATTCSLE 362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   574 DHFGTREEMFQKEIKALHAATEKLSKENESLRSKLDHANKENSDVIAL-----WKSKLETAIASHQQAMEELKVSFSKGI 648
Cdd:pfam05483  363 ELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELkkilaEDEKLLDEKKQFEKIAEELKGKEQELI 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   649 G---TDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEDQHLV 725
Cdd:pfam05483  443 FllqAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDI 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   726 --------EMEEMLSKLQEAEIKVK-ELEVLQAKYSEQ-TQVVGHLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQ 795
Cdd:pfam05483  523 inckkqeeRMLKQIENLEEKEMNLRdELESVREEFIQKgDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQ 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   796 LEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQ----VKETLEKELQTLKEKFASASEEAVSTQT 871
Cdd:pfam05483  603 IENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQkfeeIIDNYQKEIEDKKISEEKLLEEVEKAKA 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   872 SMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDN-SSQLTKMNDEL 950
Cdd:pfam05483  683 IADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNiKAELLSLKKQL 762

                          650       660
                   ....*....|....*....|....*
gi 672073054   951 RLKERSVEELQLkltKANENASLLQ 975
Cdd:pfam05483  763 EIEKEEKEKLKM---EAKENTAILK 784
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1536-2054 1.03e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 51.06  E-value: 1.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1536 NIDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELKTCcceknillrdgLNLQEECQ 1615
Cdd:PRK01156  184 NIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNEL-----------SSLEDMKN 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1616 KLNEEIREIQQTLMLEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLqtENFTLTQEKTNSE-QKVVEIIKE 1694
Cdd:PRK01156  253 RYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDI--ENKKQILSNIDAEiNKYHAIIKK 330

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1695 KELLSAETAQ-------------LAANIETLKSDFAALSKS-----------KLELQELHSCLTKILDDLRLNHEVAVTE 1750
Cdd:PRK01156  331 LSVLQKDYNDyikkksryddlnnQILELEGYEMDYNSYLKSieslkkkieeySKNIERMSAFISEILKIQEIDPDAIKKE 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1751 RAEV-------------LQDNKNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEISQlaQTNSHISADLLEAQSENRTL 1817
Cdd:PRK01156  411 LNEInvklqdisskvssLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSN--HIINHYNEKKSRLEEKIREI 488

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1818 RKDKSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKtetlASLEDTKqtnaklqSELDTLKENNLKTVEELNKSKE 1897
Cdd:PRK01156  489 EIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESAR----ADLEDIK-------IKINELKDKHDKYEEIKNRYKS 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1898 L-LNEENQKMEEFKK--------EIETLKQAAAQKSQQL----SALQEENVKLAE-------ELGRTRDEVTSHQKLEEE 1957
Cdd:PRK01156  558 LkLEDLDSKRTSWLNalavisliDIETNRSRSNEIKKQLndleSRLQEIEIGFPDdksyidkSIREIENEANNLNNKYNE 637

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1958 RSVLNNQLLEMKKRESEYRKDAdEEKASLQKSISLTSALLTEKDAELEKLRNEvtvLRGENASAKSLHSVVQTLESDKVK 2037
Cdd:PRK01156  638 IQENKILIEKLRGKIDNYKKQI-AEIDSIIPDLKEITSRINDIEDNLKKSRKA---LDDAKANRARLESTIEILRTRINE 713

                         570
                  ....*....|....*..
gi 672073054 2038 LELKVKNLELQLKENKR 2054
Cdd:PRK01156  714 LSDRINDINETLESMKK 730
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 513-1232 1.14e-05

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 50.59  E-value: 1.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   513 ELEKDLALRVQEVAELRRRLESSKPPGDVDMSLSLlqEISALQEKL----EVTHTDHQNEVTSLK---DHFGTREeMFQK 585
Cdd:pfam10174   40 ELKKERALRKEEAARISVLKEQYRVTQEENQHLQL--TIQALQDELraqrDLNQLLQQDFTTSPVdgeDKFSTPE-LTEE 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   586 EIKALHAATEKLSKENESLRSKLDHANKEnsdvIALWKSKLETAIASHQQAMEELKvsfSKGIGTDSAEF--------AE 657
Cdd:pfam10174  117 NFRRLQSEHERQAKELFLLRKTLEEMELR----IETQKQTLGARDESIKKLLEMLQ---SKGLPKKSGEEdwertrriAE 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   658 LKTQIERLR-LDYQHEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEDQHLVEMEEMLSKLQE 736
Cdd:pfam10174  190 AEMQLGHLEvLLDQKEKENIHLREELHRRNQLQPDPAKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTED 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   737 AEIKVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLL----DLDALRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNA 812
Cdd:pfam10174  270 REEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLalqtKLETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDA 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   813 esskansITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSS 892
Cdd:pfam10174  350 -------LRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKE 422

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   893 ELEKLREN-------LTDMEAKFKEKDEREDQLVKAKEKLENDIAEimkmsgdnssQLTKMNDELRLKERSVEELQLKLT 965
Cdd:pfam10174  423 RVKSLQTDssntdtaLTTLEEALSEKERIIERLKEQREREDRERLE----------ELESLKKENKDLKEKVSALQPELT 492

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   966 KANENASLLQksigevtlkaEQSQQEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEILQN 1045
Cdd:pfam10174  493 EKESSLIDLK----------EHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRIRL 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1046 FQKMLV-DTEDKLKAAQEANR--DLMQDMEELKSqaDKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALkLE 1122
Cdd:pfam10174  563 LEQEVArYKEESGKAQAEVERllGILREVENEKN--DKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQL-LE 639

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1123 KGSLLSKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEKRyqqeHRDKESLVVEREKLLKEI-NVTQEELL 1201
Cdd:pfam10174  640 EARRREDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSLAEK----DGHLTNLRAERRKQLEEIlEMKQEALL 715

                          730       740       750
                   ....*....|....*....|....*....|....*...
gi 672073054  1202 KMHMEKDS----LEAS---KVSMQVLIEELRFCKDKLM 1232
Cdd:pfam10174  716 AAISEKDAnialLELSsskKKKTQEEVMALKREKDRLV 753
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 690-1490 1.38e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.56  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   690 EMESMKAKLMKIIKEKEDSLEAVKARLDTAED---QHLVEMEEMLSKLQEAEIKVKELEVLQAKYseQTQVVGhLTSQLS 766
Cdd:pfam01576   58 EAEEMRARLAARKQELEEILHELESRLEEEEErsqQLQNEKKKMQQHIQDLEEQLDEEEAARQKL--QLEKVT-TEAKIK 134

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   767 VVEEQLLDL-DALRKANSEGKLeietlrqqlegAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVK 845
Cdd:pfam01576  135 KLEEDILLLeDQNSKLSKERKL-----------LEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGR 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   846 ETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQfnmLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKL 925
Cdd:pfam01576  204 QELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEE---LQAALARLEEETAQKNNALKKIRELEAQISELQEDL 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   926 ENDIA----------------EIMKMSGDNSSQLTKMNDELRLK-------------------ERSVEELQLKLTKANE- 969
Cdd:pfam01576  281 ESERAarnkaekqrrdlgeelEALKTELEDTLDTTAAQQELRSKreqevtelkkaleeetrshEAQLQEMRQKHTQALEe 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   970 -NASLLQKSIGEVTL-KAEQSQQEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKAS------SETKIKHEE 1041
Cdd:pfam01576  361 lTEQLEQAKRNKANLeKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESErqraelAEKLSKLQS 440

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1042 ILQNFQKMLVDTEDK-LKAAQEANR--DLMQDMEELKSQADKAK-SLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEAS 1117
Cdd:pfam01576  441 ELESVSSLLNEAEGKnIKLSKDVSSleSQLQDTQELLQEETRQKlNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLS 520

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1118 ALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEK---RYQQEHRDKESLVVEREKLLKEIN 1194
Cdd:pfam01576  521 TLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKtknRLQQELDDLLVDLDHQRQLVSNLE 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1195 VTQEELLKMHMEKDSLEASKVSMQVLIE-ELRFCKDKLMAMS---EKARAEKEQLEGQVKKLTAENMVLVKDKDDV---- 1266
Cdd:pfam01576  601 KKQKKFDQMLAEEKAISARYAEERDRAEaEAREKETRALSLAralEEALEAKEELERTNKQLRAEMEDLVSSKDDVgknv 680

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1267 --IQKLQSAYEELVKDQKALVQEIEDlttEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQ-EKLSAS 1343
Cdd:pfam01576  681 heLERSKRALEQQVEEMKTQLEELED---ELQATEDAKLRLEVNMQALKAQFERDLQARDEQGEEKRRQLVKQvRELEAE 757

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1344 LE-------ATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRA---ITDSEC------ 1407
Cdd:pfam01576  758 LEderkqraQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDeilAQSKESekklkn 837

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1408 --IQLLHEKESLAASERA---LLAEKEELLNENRVITEKLNKHSEEVTRLEV---SLNEKITYLTSEKEMACQKVARLKK 1479
Cdd:pfam01576  838 leAELLQLQEDLAASERArrqAQQERDELADEIASGASGKSALQDEKRRLEAriaQLEEELEEEQSNTELLNDRLRKSTL 917

                          890
                   ....*....|.
gi 672073054  1480 QQDSLLKEKSA 1490
Cdd:pfam01576  918 QVEQLTTELAA 928
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1029-1771 1.57e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 1.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1029 EKASSETKIKHEEILQNFQKMLVDTEDKLKAaqeanRDLMQDMEELKsqadkAKSLTYLLTSAKKEIEVMSEELRGLKSE 1108
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRREREKAERY-----QALLKEKREYE-----GYELLKEKEALERQKEAIERQLASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1109 KQLFAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKlwSVNENLH-LEKERISEEKQVAEKRYQQEHRDKES--LVVE 1185
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQL--RVKEKIGeLEAEIASLERSIAEKERELEDAEERLakLEAE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1186 REKLLKEINVTQEELLKMHMEKDSLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKD- 1264
Cdd:TIGR02169  331 IDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDr 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1265 --DVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLSA 1342
Cdd:TIGR02169  411 lqEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1343 SLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRA--------ITDSECIQLLHEK 1414
Cdd:TIGR02169  491 ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLnnvvveddAVAKEAIELLKRR 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1415 E----------SLAASERAL--------------------------------------LAEKEELLNENRVIT------E 1440
Cdd:TIGR02169  571 KagratflplnKMRDERRDLsilsedgvigfavdlvefdpkyepafkyvfgdtlvvedIEAARRLMGKYRMVTlegelfE 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1441 K---------------LNKHSEEVTRLEvsLNEKITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESS 1505
Cdd:TIGR02169  651 KsgamtggsraprggiLFSRSEPAELQR--LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQL 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1506 IKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKENQELASSKCDLSLML-----KEAQTAKKNLEKEHT 1580
Cdd:TIGR02169  729 EQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLshsriPEIQAELSKLEEEVS 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1581 SMMQAKEDLNAELKTCCCEKNILLRDGLNLQEECQKLNEEIREIQQT---LMLEKEARAKESESSLYESNKLHGRIVLLE 1657
Cdd:TIGR02169  809 RIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEienLNGKKEELEEELEELEAALRDLESRLGDLK 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1658 EEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAA---LSKSKLELQELHSCLT 1734
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEelsLEDVQAELQRVEEEIR 968

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 672073054  1735 KI-----------------LDDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLR 1771
Cdd:TIGR02169  969 ALepvnmlaiqeyeevlkrLDELKEKRAKLEEERKAILERIEEYEKKKREVFME 1022
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1076-1301 2.81e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1076 SQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKLWSVNENLH 1155
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1156 LEKERISEE-KQVAEKRYQQEHRDKESLV---------VEREKLLKEINVTQEELLkmhmekDSLEASKVSMQVLIEELR 1225
Cdd:COG4942    97 AELEAQKEElAELLRALYRLGRQPPLALLlspedfldaVRRLQYLKYLAPARREQA------EELRADLAELAALRAELE 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672073054 1226 FCKDKLMAMSEKARAEKEQLEgqvkKLTAENMVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEK 1301
Cdd:COG4942   171 AERAELEALLAELEEERAALE----ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 425-1391 3.05e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.66  E-value: 3.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   425 ELLNQLEEEKRKVED-LQFRVEEESITKGDLEQKSQISEDPENTQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVA 503
Cdd:TIGR00606  210 KYLKQYKEKACEIRDqITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   504 TVSEK------SRIMELEKDLALRVQEVAELRRRLESSKPPGDVDMSL------SLLQEISALQEKLEVtHTDHQNEVTS 571
Cdd:TIGR00606  290 LKMEKvfqgtdEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLlnqektELLVEQGRLQLQADR-HQEHIRARDS 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   572 LKDHFGTREEM--------FQKEIKALHaateKLSKENESLRSKLdhankensdvIALWKSKLETAIASHQQAMEELKVS 643
Cdd:TIGR00606  369 LIQSLATRLELdgfergpfSERQIKNFH----TLVIERQEDEAKT----------AAQLCADLQSKERLKQEQADEIRDE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   644 FSKGIGTDSAEFAELKTQIERLRldyqHEIESLQSKQDSersahakemesmkaklMKIIKEKEDSLEAVKARLDTAEDQH 723
Cdd:TIGR00606  435 KKGLGRTIELKKEILEKKQEELK----FVIKELQQLEGS----------------SDRILELDQELRKAERELSKAEKNS 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   724 LVE---MEEMLSKLQEAEIkVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEGKLEIETlrqqLEGAE 800
Cdd:TIGR00606  495 LTEtlkKEVKSLQNEKADL-DRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTS----LLGYF 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   801 KQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEK-FASASEEAVstQTSMQDTVNK 879
Cdd:TIGR00606  570 PNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlFDVCGSQDE--ESDLERLKEE 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   880 LHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEE 959
Cdd:TIGR00606  648 IEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDE 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   960 LQLKLTKANENASLLQKSIGEVTLKAEQSQQEAAKKHEEEKKELENKLLELEKkmETSHYQCQDLKAKYEKASSETKIKH 1039
Cdd:TIGR00606  728 MLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPE--EESAKVCLTDVTIMERFQMELKDVE 805

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1040 EEILQNFQKMlvDTEDKLKAAQEANRDLMQDMEELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASAL 1119
Cdd:TIGR00606  806 RKIAQQAAKL--QGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1120 KLEKGSLLSKLIEVETKITLLQEdqqklwsvnenlhlEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQEE 1199
Cdd:TIGR00606  884 QQFEEQLVELSTEVQSLIREIKD--------------AKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEK 949

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1200 LLKMHMEKDSLEAskvsmQVLIEELRFCKDKLMAMSeKARAEKEQLEGQVKKLTAENMVLVKDKDDviqklQSAYEELVK 1279
Cdd:TIGR00606  950 VKNIHGYMKDIEN-----KIQDGKDDYLKQKETELN-TVNAQLEECEKHQEKINEDMRLMRQDIDT-----QKIQERWLQ 1018

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1280 DQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLSAsleatlqvKQLLSTEAE 1359
Cdd:TIGR00606 1019 DNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYE--------KEIKHFKKE 1090

                          970       980       990
                   ....*....|....*....|....*....|..
gi 672073054  1360 TLRTQLDCATKALRKAELDMRQLQTSNTSLTK 1391
Cdd:TIGR00606 1091 LREPQFRDAEEKYREMMIVMRTTELVNKDLDI 1122
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1764-2016 3.47e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 3.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1764 EKREMMLRNEEVLKEKEKLEESYFVLQKEISQLAQtnshisadLLEAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTA 1843
Cdd:COG4913   219 EEPDTFEAADALVEHFDDLERAHEALEDAREQIEL--------LEPIRELAERYAAARERLAELEYLRAALRLWFAQRRL 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1844 EDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKEnnlktveelnkskELLNEENQKMEEFKKEIETLKQAAAQK 1923
Cdd:COG4913   291 ELLEAELEELRAELARLEAELERLEARLDALREELDELEA-------------QIRGNGGDRLEQLEREIERLERELEER 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1924 SQQLSALQEenvkLAEELGRTRDEvtSHQKLEEERSVLNNQLLEMKKRESEYRKDADEEKASLQksisltsalltEKDAE 2003
Cdd:COG4913   358 ERRRARLEA----LLAALGLPLPA--SAEEFAALRAEAAALLEALEEELEALEEALAEAEAALR-----------DLRRE 420

                         250
                  ....*....|...
gi 672073054 2004 LEKLRNEVTVLRG 2016
Cdd:COG4913   421 LRELEAEIASLER 433
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1129-1828 3.73e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 3.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1129 KLIEVETKITLLQEDQQKLWSVNENL-----HLEKERISEEKQVAEKRyqQEHRDKESLVVEREKLLKEINVTQEELLKM 1203
Cdd:PRK03918  166 NLGEVIKEIKRRIERLEKFIKRTENIeelikEKEKELEEVLREINEIS--SELPELREELEKLEKEVKELEELKEEIEEL 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1204 HMEKDSLEASKVSMQVLIEELRfckdklmAMSEKARAEKEQLEGQVKKLTAenmvlvkdkddvIQKLQSAYEELVKDQKA 1283
Cdd:PRK03918  244 EKELESLEGSKRKLEEKIRELE-------ERIEELKKEIEELEEKVKELKE------------LKEKAEEYIKLSEFYEE 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1284 LVQEIEDLTTEKKSAAEKQMNLDNtcltLKAERENLLQSNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLsTEAETLRT 1363
Cdd:PRK03918  305 YLDELREIEKRLSRLEEEINGIEE----RIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKK-EELERLKK 379

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1364 QLDCATKALRKAELDmrQLQTSNTSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERALLAEKEELLNENRviTEKLN 1443
Cdd:PRK03918  380 RLTGLTPEKLEKELE--ELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHR--KELLE 455

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1444 KHSEEVTRLEVSLnEKITYLTSEKEMACQKVARLKKQQDSLLKEKSALevqngDLLADRESSIKAIGdlKRKYEQEATNR 1523
Cdd:PRK03918  456 EYTAELKRIEKEL-KEIEEKERKLRKELRELEKVLKKESELIKLKELA-----EQLKELEEKLKKYN--LEELEKKAEEY 527

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1524 RLAVQEKVKLLGNIDALKKELqqrkKENQELASSKCDLSLMLKEAQTAKKNLEKEHTSM-MQAKEDLNAELKTcccekni 1602
Cdd:PRK03918  528 EKLKEKLIKLKGEIKSLKKEL----EKLEELKKKLAELEKKLDELEEELAELLKELEELgFESVEELEERLKE------- 596

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1603 lLRDGLNLQEECQKLNEEIREIQQTLMLEKEarakESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENftLTQEKT 1682
Cdd:PRK03918  597 -LEPFYNEYLELKDAEKELEREEKELKKLEE----ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEE--LREEYL 669

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1683 NSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKiLDDLRlnhevavteraevlqdnknll 1762
Cdd:PRK03918  670 ELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALER-VEELR--------------------- 727

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672073054 1763 aekremmlrnEEVLKEKEKLEESYFvlqKEISQLAqtnSHISADLLEAQSENRTLRKDKSKLTLKI 1828
Cdd:PRK03918  728 ----------EKVKKYKALLKERAL---SKVGEIA---SEIFEELTEGKYSGVRVKAEENKVKLFV 777
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1129-2038 3.74e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.27  E-value: 3.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1129 KLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAekryqqehRDKESLVVEREKLLKEINVTQEELLKMHMEKD 1208
Cdd:TIGR00606  201 KVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIV--------KSYENELDPLKNRLKEIEHNLSKIMKLDNEIK 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1209 SLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKddvIQKLQSAYEELVKDQKALVQEI 1288
Cdd:TIGR00606  273 ALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRE---LEKLNKERRLLNQEKTELLVEQ 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1289 EDLTTEKKSAAEKQMNLDNTCLTLKAERE-NLLQSNRDLQFEKDT----LRQGQE-------KLSASLEATLQVKQLLST 1356
Cdd:TIGR00606  350 GRLQLQADRHQEHIRARDSLIQSLATRLElDGFERGPFSERQIKNfhtlVIERQEdeaktaaQLCADLQSKERLKQEQAD 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1357 EAE--------TLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLE-EIKTCRAITDSECIQLLHEKESLAASERALLAE 1427
Cdd:TIGR00606  430 EIRdekkglgrTIELKKEILEKKQEELKFVIKELQQLEGSSDRILElDQELRKAERELSKAEKNSLTETLKKEVKSLQNE 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1428 KEELLNENRVITEK---LNKHSEEVTRLEVSLNEKITYLTSEKEMACQKVARL---------KKQQDSLLKEKSALEVQN 1495
Cdd:TIGR00606  510 KADLDRKLRKLDQEmeqLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELtsllgyfpnKKQLEDWLHSKSKEINQT 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1496 GDLLADRESSIKAIGDLK---RKYEQEATNRRLAVQEKV-------KLLGNIDALKKELQQRKKENQELASSKCDLSLML 1565
Cdd:TIGR00606  590 RDRLAKLNKELASLEQNKnhiNNELESKEEQLSSYEDKLfdvcgsqDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFI 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1566 KEAQTAKKNLEKEHTSMMQAKEDLNAELKtcccEKNILLRDGLNLQEECQKLNEEIREIQQTLMLEKEARAKESESSLYE 1645
Cdd:TIGR00606  670 TQLTDENQSCCPVCQRVFQTEAELQEFIS----DLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKE 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1646 SNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSE--QKVVEIIK----EKELLSAETAQLAANIETLKSDFAAL 1719
Cdd:TIGR00606  746 IPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvcLTDVTIMErfqmELKDVERKIAQQAAKLQGSDLDRTVQ 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1720 SKSKlELQELHSCLTKILDDLRLNHEVaVTERAEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEISQLaqt 1799
Cdd:TIGR00606  826 QVNQ-EKQEKQHELDTVVSKIELNRKL-IQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSL--- 900

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1800 NSHISADLLEAQSENRTLRKDKSKLTLKIRELETlhsftAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNaklqseld 1879
Cdd:TIGR00606  901 IREIKDAKEQDSPLETFLEKDQQEKEELISSKET-----SNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDG-------- 967

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1880 tlKENNLKTVE-ELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQ--------EENVKLAEELGRTRD---- 1946
Cdd:TIGR00606  968 --KDDYLKQKEtELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQdnltlrkrENELKEVEEELKQHLkemg 1045

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1947 ------EVTSHQKLEEERSVLNNQLLEMKKRESEYRKDADEEKASLQKSisltsallTEKDAElEKLRNEVTVLRGENAS 2020
Cdd:TIGR00606 1046 qmqvlqMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREP--------QFRDAE-EKYREMMIVMRTTELV 1116

                          970
                   ....*....|....*...
gi 672073054  2021 AKSLHSVVQTLESDKVKL 2038
Cdd:TIGR00606 1117 NKDLDIYYKTLDQAIMKF 1134
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1054-1569 4.34e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 48.95  E-value: 4.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1054 EDKLKAAQEANRDLMQDmEELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKLIEV 1133
Cdd:pfam05483  265 ESRDKANQLEEKTKLQD-ENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKA 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1134 ETKITLL-QEDQQKLWSVNENLHLEKERIsEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKMHMEKDSLEA 1212
Cdd:pfam05483  344 KAAHSFVvTEFEATTCSLEELLRTEQQRL-EKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLD 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1213 SKVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKDDVIQKLQ----------SAYEELVKDQK 1282
Cdd:pfam05483  423 EKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEkeklknieltAHCDKLLLENK 502

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1283 ALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLR 1362
Cdd:pfam05483  503 ELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEV 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1363 TQLDCATKALRKAELDMR-QLQTSNTSLTKLLEEIKTCRAITDSECIQllhekesLAASERALLAEKEELLNENRVITEK 1441
Cdd:pfam05483  583 LKKEKQMKILENKCNNLKkQIENKNKNIEELHQENKALKKKGSAENKQ-------LNAYEIKVNKLELELASAKQKFEEI 655

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1442 LNKHSEEVTRLEVSlNEKITYLTSEKEMACQKVARLKKQQDSLLKEKSALEV--------QNGDLLADRESSIkaigDLK 1513
Cdd:pfam05483  656 IDNYQKEIEDKKIS-EEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMValmekhkhQYDKIIEERDSEL----GLY 730

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 672073054  1514 RKYEQEATNRRLAVQEKVKLLGN-IDALKKELQQRKKENQELASSKCDLSLMLKEAQ 1569
Cdd:pfam05483  731 KNKEQEQSSAKAALEIELSNIKAeLLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1857-2100 4.52e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.90  E-value: 4.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1857 KTETLASLEDTKQTNAKLQ---SELDTLKENNLKTVEELNKSKELLNEENQK--------MEEFKKEIETLKQAAAQKSQ 1925
Cdd:TIGR02168  174 RKETERKLERTRENLDRLEdilNELERQLKSLERQAEKAERYKELKAELRELelallvlrLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1926 QLSALQEENVKLAEELGRTRDEVTS-HQKLEEERSVLNNQLLEMKKRESEYRKdADEEKASLQKSISLTSALLTEKDAEL 2004
Cdd:TIGR02168  254 ELEELTAELQELEEKLEELRLEVSElEEEIEELQKELYALANEISRLEQQKQI-LRERLANLERQLEELEAQLEELESKL 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  2005 EKLRNEVTVLRGENASAKslhSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDvQTEEDERAQESQIDFLNSV 2084
Cdd:TIGR02168  333 DELAEELAELEEKLEELK---EELESLEAELEELEAELEELESRLEELEEQLETLRSKVA-QLELQIASLNNEIERLEAR 408

                          250
                   ....*....|....*.
gi 672073054  2085 IVDLQRKNQDLKMKVE 2100
Cdd:TIGR02168  409 LERLEDRRERLQQEIE 424
COG5022 COG5022
Myosin heavy chain [General function prediction only];
664-1159 4.95e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.92  E-value: 4.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  664 RLRLDY-QHEIESLQSKQDSERSAHAKEMEsMKAKLMKIIKekedsleavkARLDTAEDqhlveMEEMLSKLqeAEIKVK 742
Cdd:COG5022   761 RRRYLQaLKRIKKIQVIQHGFRLRRLVDYE-LKWRLFIKLQ----------PLLSLLGS-----RKEYRSYL--ACIIKL 822

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  743 ELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEGKLEI-ETLRQQLEGAEKQIKNLEME-RNAESSKANSI 820
Cdd:COG5022   823 QKTIKREKKLRETEEVEFSLKAEVLIQKFGRSLKAKKRFSLLKKETIyLQSAQRVELAERQLQELKIDvKSISSLKLVNL 902

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  821 TKDLQGKELMlTSLQSNLNEVNQVKETLEKELQTLKEKfaSASEEAVSTQTSMQDTVNKLHQKEeqfnmlsSELEKLREN 900
Cdd:COG5022   903 ELESEIIELK-KSLSSDLIENLEFKTELIARLKKLLNN--IDLEEGPSIEYVKLPELNKLHEVE-------SKLKETSEE 972

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  901 LTDMeakFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSqLTKMNDELRLKERSVEELQ------LKLTKANENASLL 974
Cdd:COG5022   973 YEDL---LKKSTILVREGNKANSELKNFKKELAELSKQYGA-LQESTKQLKELPVEVAELQsaskiiSSESTELSILKPL 1048

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  975 QKSIGEVTLKAEQSQQEAakKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEILQNfqkmLVDTE 1054
Cdd:COG5022  1049 QKLKGLLLLENNQLQARY--KALKLRRENSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPANVLQF----IVAQM 1122

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1055 DKLKAAQEA---NRDLMQDMEELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFaqEASALKLEKGSLLSKLI 1131
Cdd:COG5022  1123 IKLNLLQEIskfLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAALSEKRLY--QSALYDEKSKLSSSEVN 1200

                         490       500
                  ....*....|....*....|....*....
gi 672073054 1132 EVETKITLLQEDQQKLWSVN-ENLHLEKE 1159
Cdd:COG5022  1201 DLKNELIALFSKIFSGWPRGdKLKKLISE 1229
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1031-2099 5.13e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.58  E-value: 5.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1031 ASSETKIKHEEILQNFQKMLVDTEDKLKAAQEANRDLMQDMeelKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQ 1110
Cdd:pfam15921  128 AMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDS---NTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKI 204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1111 LFAQEASALKLEK-GSLLSKLI-EVETKITLLQedqQKLWSVNENLhlekERISEEKQVAEKRYQQEHRDK-ESLVVERE 1187
Cdd:pfam15921  205 YEHDSMSTMHFRSlGSAISKILrELDTEISYLK---GRIFPVEDQL----EALKSESQNKIELLLQQHQDRiEQLISEHE 277

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1188 KllkEINVTQEELLKMHMEKDSLEAskvsmqvlieelrfckdKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKDDVI 1267
Cdd:pfam15921  278 V---EITGLTEKASSARSQANSIQS-----------------QLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAK 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1268 QKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAErenLLQSNRDLQFEKD-TLRQGQEKLSASLEA 1346
Cdd:pfam15921  338 RMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLAD---LHKREKELSLEKEqNKRLWDRDTGNSITI 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1347 TLQVKQLLSTEAETLRtqLDCATKALR-----KAELDMRQLQTSNTSLTKLleeiktcraitDSECIQLLHEKESLAASE 1421
Cdd:pfam15921  415 DHLRRELDDRNMEVQR--LEALLKAMKsecqgQMERQMAAIQGKNESLEKV-----------SSLTAQLESTKEMLRKVV 481

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1422 RALLAEKEELLNENRVITEkLNKHSEEVTRLEVSLNEKITYLTSEKEMACQKVARLKKQQDSLLK---EKSALEVQngdl 1498
Cdd:pfam15921  482 EELTAKKMTLESSERTVSD-LTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNvqtECEALKLQ---- 556

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1499 LADRESSIKAIgdlkrkyEQEATNRRLAVQEKVKLLGNIDA----LKKELQQRKKENQELASSKCDLSLMLKEAQTAKKN 1574
Cdd:pfam15921  557 MAEKDKVIEIL-------RQQIENMTQLVGQHGRTAGAMQVekaqLEKEINDRRLELQEFKILKDKKDAKIRELEARVSD 629

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1575 LEKEHTSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEECQKLNEEIReiqqtlMLEKEARAKeSESSLYESNKLHGRIV 1654
Cdd:pfam15921  630 LELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE------VLKRNFRNK-SEEMETTTNKLKMQLK 702

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1655 LLEEEIQglrtcseqlQTENFTLTQEKTNSEQKVVEIIKEKELLS--AETAQLAANIETLKSDFAALSKSKLELQELHSC 1732
Cdd:pfam15921  703 SAQSELE---------QTRNTLKSMEGSDGHAMKVAMGMQKQITAkrGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNK 773

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1733 LTKILddlrlnhevavteraEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEEsyFVLQKEISQLAQTNshisaDLLEAQS 1812
Cdd:pfam15921  774 LSQEL---------------STVATEKNKMAGELEVLRSQERRLKEKVANME--VALDKASLQFAECQ-----DIIQRQE 831

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1813 ENRTlrKDKSKLTLKIRELETlhsftAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSEldTLKENNLKTvEEL 1892
Cdd:pfam15921  832 QESV--RLKLQHTLDVKELQG-----PGYTSNSSMKPRLLQPASFTRTHSNVPSSQSTASFLSHH--SRKTNALKE-DPT 901

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1893 NKSKELLNEenqkmeefkkeietlKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERS-VLNNQLLEMKKR 1971
Cdd:pfam15921  902 RDLKQLLQE---------------LRSVINEEPTVQLSKAEDKGRAPSLGALDDRVRDCIIESSLRSdICHSSSNSLQTE 966

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1972 ESEYRKDADEEKASLQKS-ISLTSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNlelqlk 2050
Cdd:pfam15921  967 GSKSSETCSREPVLLHAGeLEDPSSCFTFPSTASPSVKNSASRSFHSSPKKSPVHSLLTSSAEGSIGSSSQYRS------ 1040

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 672073054  2051 enKRQLSSSSGNTDVQTEEDE------RAQESQIDFLNSVIVDLQRKNQDLKMKV 2099
Cdd:pfam15921 1041 --AKTIHSPDSVKDSQSLPIEttgktcRKLQNRLESLQTLVEDLQLKNQAMSSMI 1093
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1235-1979 6.47e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.43  E-value: 6.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1235 SEKARAEKEQLEGQVKKLTAENMVlvKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQmNLDNTCLTLKA 1314
Cdd:TIGR00618  191 SLHGKAELLTLRSQLLTLCTPCMP--DTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL-KKQQLLKQLRA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1315 ERENL--LQSNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQ---LQTSNTSL 1389
Cdd:TIGR00618  268 RIEELraQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQqssIEEQRRLL 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1390 TKLLEEIKTCRAITDSECIQLLHEKESLAASE--RALLAEKEELLNENRVITEKLNKHSEEVTrlevslneKITYLTSEK 1467
Cdd:TIGR00618  348 QTLHSQEIHIRDAHEVATSIREISCQQHTLTQhiHTLQQQKTTLTQKLQSLCKELDILQREQA--------TIDTRTSAF 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1468 EMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKY----EQEATNRRLAVQEKVKllgnidalKKE 1543
Cdd:TIGR00618  420 RDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLkereQQLQTKEQIHLQETRK--------KAV 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1544 LQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEhTSMMQAKEDLNAELKTcccEKNILLRDGLNLQEECQKLNEEIRE 1623
Cdd:TIGR00618  492 VLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPL-TRRMQRGEQTYAQLET---SEEDVYHQLTSERKQRASLKEQMQE 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1624 IQQTLMLEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETA 1703
Cdd:TIGR00618  568 IQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTA 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1704 QLAANIETLKSDFAALSKSKLELQELhscltkiLDDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVLKEKEKL- 1782
Cdd:TIGR00618  648 LHALQLTLTQERVREHALSIRVLPKE-------LLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREf 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1783 EESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKdkskltlkireletlHSFTAAQTAEDAMQIMEQMTKEKTETLA 1862
Cdd:TIGR00618  721 NEIENASSSLGSDLAAREDALNQSLKELMHQARTVLK---------------ARTEAHFNNNEEVTAALQTGAELSHLAA 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1863 SLEDTKQTNAKLQSELdtlkennlktveelnksKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQEENvklaeelG 1942
Cdd:TIGR00618  786 EIQFFNRLREEDTHLL-----------------KTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEK-------S 841

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 672073054  1943 RTRDEVTSHQKLEEERSVLNNQLLEMKKRESEYRKDA 1979
Cdd:TIGR00618  842 ATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
335-535 7.11e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 7.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  335 LTETSSRYARKISGTTALQEALKEKQQHIEQLlAERDLERAEVAKATSHVGEIEQELALARDGHDQhVLELEAKMDQLRT 414
Cdd:COG4913   622 LEEELAEAEERLEALEAELDALQERREALQRL-AEYSWDEIDVASAEREIAELEAELERLDASSDD-LAALEEQLEELEA 699

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  415 MVEAADREKVELLNQLEEEKRKVEDLQFRVEEesiTKGDLEQKSQISEDPENT--QTKLEHARIKELEQSLLF------- 485
Cdd:COG4913   700 ELEELEEELDELKGEIGRLEKELEQAEEELDE---LQDRLEAAEDLARLELRAllEERFAAALGDAVERELREnleerid 776

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 672073054  486 -EKTKADKLQRELEDTRVATVSE-KSRIMELEKDLAlRVQEVAELRRRLESS 535
Cdd:COG4913   777 aLRARLNRAEEELERAMRAFNREwPAETADLDADLE-SLPEYLALLDRLEED 827
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 584-1147 8.70e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 47.79  E-value: 8.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   584 QKEIKALHAATEKLSKENESLRSKLDHANKENSDVIA------LWKSKLETAIAS----------HQQAMEELKVSFSKG 647
Cdd:pfam05483  112 RKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKennatrHLCNLLKETCARsaektkkyeyEREETRQVYMDLNNN 191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   648 IGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEM---ESMKAKLMKIIKEKEDSLEAVKARLDTAED--- 721
Cdd:pfam05483  192 IEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEIndkEKQVSLLLIQITEKENKMKDLTFLLEESRDkan 271

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   722 --------------QHLVEMEEMLSKLQEAEIKVKELEVLQAKYSEQTQVVGHLTSQLSVVEE-QLLDLDALRKANSEGK 786
Cdd:pfam05483  272 qleektklqdenlkELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEaQMEELNKAKAAHSFVV 351

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   787 LEIETL-----------RQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNE----------VNQVK 845
Cdd:pfam05483  352 TEFEATtcsleellrteQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEdeklldekkqFEKIA 431

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   846 ETLEKE-------LQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQF--------------NMLSSELEKLRENLTDM 904
Cdd:pfam05483  432 EELKGKeqeliflLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELekeklknieltahcDKLLLENKELTQEASDM 511

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   905 EAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKErsvEELQLKLTKANENASL----------- 973
Cdd:pfam05483  512 TLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKG---DEVKCKLDKSEENARSieyevlkkekq 588

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   974 ----------LQKSIGEVTLKAEQSQQEAAKKHEEEKKELEN------KLLELEKKMETSHYQCQDLKAKYEKASSETKI 1037
Cdd:pfam05483  589 mkilenkcnnLKKQIENKNKNIEELHQENKALKKKGSAENKQlnayeiKVNKLELELASAKQKFEEIIDNYQKEIEDKKI 668

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1038 KHEEILQNFQKMLVDTEDKLKAAQEANRDLMQDMEELKSQADKAKSltylltSAKKEIEVMSEELRGLKSEKQLFAQEAS 1117
Cdd:pfam05483  669 SEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKH------QYDKIIEERDSELGLYKNKEQEQSSAKA 742

                          650       660       670
                   ....*....|....*....|....*....|
gi 672073054  1118 ALKLEKGSLLSKLIEVETKITLLQEDQQKL 1147
Cdd:pfam05483  743 ALEIELSNIKAELLSLKKQLEIEKEEKEKL 772
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1657-2100 1.05e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.71  E-value: 1.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1657 EEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELH------ 1730
Cdd:TIGR04523   67 EEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIdkflte 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1731 -SCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEIsqlaQTNSHISADLLE 1809
Cdd:TIGR04523  147 iKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKI----QKNKSLESQISE 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1810 AQSENRTLRKDKSKLTLKIRELETLHSFTAAQTaedaMQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKtV 1889
Cdd:TIGR04523  223 LKKQNNQLKDNIEKKQQEINEKTTEISNTQTQL----NQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSE-I 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1890 EELNKSK----------ELLNEENQKME------EFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEV----- 1948
Cdd:TIGR04523  298 SDLNNQKeqdwnkelksELKNQEKKLEEiqnqisQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIeklkk 377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1949 ------TSHQKLEEERSVLNNQLLEMKKRESEYR---KDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLrgeNA 2019
Cdd:TIGR04523  378 enqsykQEIKNLESQINDLESKIQNQEKLNQQKDeqiKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVK---EL 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  2020 SAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSssgntdvqteederaQESQIDFLNSVIVDLQRKNQDLKMKV 2099
Cdd:TIGR04523  455 IIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKS---------------KEKELKKLNEEKKELEEKVKDLTKKI 519


                   .
gi 672073054  2100 E 2100
Cdd:TIGR04523  520 S 520
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1872-2017 1.16e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.07  E-value: 1.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1872 AKLQSELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRD--EVT 1949
Cdd:COG1579    13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNnkEYE 92

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672073054 1950 SHQK----LEEERSVLNNQLLEMKKRESEYRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGE 2017
Cdd:COG1579    93 ALQKeiesLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1073-1974 1.20e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.48  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1073 ELKSQADKAKSLTYLLTSAKKEIEVMSEELrglksEKQLFAQEAS--ALKLEKGSLLSKLIEVETKITLLQEDQQKLwsv 1150
Cdd:pfam01576   79 ELESRLEEEEERSQQLQNEKKKMQQHIQDL-----EEQLDEEEAArqKLQLEKVTTEAKIKKLEEDILLLEDQNSKL--- 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1151 NENLHLEKERISE------EKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKMhmeKDSLEASKVSMQVLIEEL 1224
Cdd:pfam01576  151 SKERKLLEERISEftsnlaEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKA---KRKLEGESTDLQEQIAEL 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1225 RfckdklmamsekarAEKEQLEGQVKKltaenmvlvkdKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEkksAAEKQMN 1304
Cdd:pfam01576  228 Q--------------AQIAELRAQLAK-----------KEEELQAALARLEEETAQKNNALKKIRELEAQ---ISELQED 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1305 LDNTcltlKAERENLLQSNRDLQFEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQT 1384
Cdd:pfam01576  280 LESE----RAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHT 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1385 SN-TSLTKLLEEIKTCRAITDSECIQLLHEKESLAASERALLAEKEELLNENR---VITEKLNKHSEEVTRLEVSLNEKI 1460
Cdd:pfam01576  356 QAlEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKkleGQLQELQARLSESERQRAELAEKL 435

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1461 TYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGD---LLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGN- 1536
Cdd:pfam01576  436 SKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDtqeLLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNv 515

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1537 ---IDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEE 1613
Cdd:pfam01576  516 erqLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQL 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1614 CQKLNEEIREIQQTLMLEKEARAK---ESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQE-------KTN 1683
Cdd:pfam01576  596 VSNLEKKQKKFDQMLAEEKAISARyaeERDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEmedlvssKDD 675

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1684 SEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQelhscltKILDDLRLNHEVAVTERAEVLQDNKNLLA 1763
Cdd:pfam01576  676 VGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLE-------VNMQALKAQFERDLQARDEQGEEKRRQLV 748

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1764 EK-REMMLRNEEVLKEKEKLEESYFVLQKEISQLaqtNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLHS-----F 1837
Cdd:pfam01576  749 KQvRELEAELEDERKQRAQAVAAKKKLELDLKEL---EAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARAsrdeiL 825

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1838 TAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELNKSKELLNEENQKMEEfkkEIETLK 1917
Cdd:pfam01576  826 AQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEE---ELEEEQ 902

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 672073054  1918 QAAAQKSQQLSALQEENVKLAEELGRTRdevTSHQKLEEERSVLNNQLLEMKKRESE 1974
Cdd:pfam01576  903 SNTELLNDRLRKSTLQVEQLTTELAAER---STSQKSESARQQLERQNKELKAKLQE 956
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 551-955 1.26e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.53  E-value: 1.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   551 ISALQEKLEVTHTDHQNEVTSLKDHFGTREEMFQKEIKALHAATEKLSKENESLRSKLDHANKENSDVIALWKSKLETaI 630
Cdd:pfam12128  274 IASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQLPS-W 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   631 ASHQQAMEELKVSFSKGIGTDSAEFAELKTQIErlrLDYQHEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKEDSLE 710
Cdd:pfam12128  353 QSELENLEERLKALTGKHQDVTAKYNRRRSKIK---EQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLE 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   711 AVKARLDTAEDQHLVEMEEMLSKLQEAEIKVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKA--NSEGKLE 788
Cdd:pfam12128  430 AGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRrdQASEALR 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   789 IETLR-QQLEGAEKQIKN---------LEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKET----LEKELQT 854
Cdd:pfam12128  510 QASRRlEERQSALDELELqlfpqagtlLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELnlygVKLDLKR 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   855 LKEKFASASEEAV-----STQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDI 929
Cdd:pfam12128  590 IDVPEWAASEEELrerldKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKK 669

                          410       420
                   ....*....|....*....|....*..
gi 672073054   930 AEIMKMSGDNS-SQLTKMNDELRLKER 955
Cdd:pfam12128  670 NKALAERKDSAnERLNSLEAQLKQLDK 696
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
355-530 1.35e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.16  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  355 ALKEKQQHIEQLLAE---RDLERAEVAKATS-----------HVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAAD 420
Cdd:COG2433   347 AYKNKFERVEKKVPPdvdRDEVKARVIRGLSieealeeliekELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLE 426

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  421 REKVELLNQLEEEKRKVEDLQFRVEEESItkgdlEQKSQISEDPEntQTKLEhARIKELEQSLLFEKTKADKLQRELEDT 500
Cdd:COG2433   427 AEVEELEAELEEKDERIERLERELSEARS-----EERREIRKDRE--ISRLD-REIERLERELEEERERIEELKRKLERL 498

                         170       180       190
                  ....*....|....*....|....*....|.
gi 672073054  501 RvatvseksRIMELE-KDLALRVQEVAELRR 530
Cdd:COG2433   499 K--------ELWKLEhSGELVPVKVVEKFTK 521
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1749-2100 1.62e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 1.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1749 TERAEVLQDNKNLLAEKRemmlRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKI 1828
Cdd:PRK02224  213 SELAELDEEIERYEEQRE----QARETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1829 RELETLHSFTAAQT------AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVE------------ 1890
Cdd:PRK02224  289 EELEEERDDLLAEAglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEEraeelreeaael 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1891 --ELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQ-KLEEERSVL--NNQL 1965
Cdd:PRK02224  369 esELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTARERVeeAEAL 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1966 LEMKK--------RESEYRKDADEEKASLQksisltsalltEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVK 2037
Cdd:PRK02224  449 LEAGKcpecgqpvEGSPHVETIEEDRERVE-----------ELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEER 517

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 672073054 2038 LELKVKNLELQ---LKENKRQLSSSSGNTD------VQTEEDERAQESQIDFLNSVIVDLQRKNQDLKMKVE 2100
Cdd:PRK02224  518 REDLEELIAERretIEEKRERAEELRERAAeleaeaEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIE 589
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1413-2017 1.72e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.09  E-value: 1.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1413 EKESLAASERALLAEKEELLNENRVITEKLNKH---SEEVTRLEVSLNEKITYLTSEKEMACQKVARLKKQQDSLLKEKS 1489
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHqqlCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1490 ALEVQ---NGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNI-----DALKKELQQRK--KENQELASSKC 1559
Cdd:pfam01576   83 RLEEEeerSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIkkleeDILLLEDQNSKlsKERKLLEERIS 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1560 DLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEECQKLNEEIREIQQTLMLEKEARAKEs 1639
Cdd:pfam01576  163 EFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKK- 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1640 esslyesnklhgrivllEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQ-------LAANIETL 1712
Cdd:pfam01576  242 -----------------EEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKaekqrrdLGEELEAL 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1713 KSDFAALSKSKLELQELHS-------CLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVL-KEKEKLEE 1784
Cdd:pfam01576  305 KTELEDTLDTTAAQQELRSkreqevtELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLeKAKQALES 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1785 SYFVLQKEISQLAQtnshisadlleAQSENRTLRKdksKLTLKIRELETLHSFTAAQTAEdAMQIMEQMTKEKTETLASL 1864
Cdd:pfam01576  385 ENAELQAELRTLQQ-----------AKQDSEHKRK---KLEGQLQELQARLSESERQRAE-LAEKLSKLQSELESVSSLL 449

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1865 EDTKQTNAKLQSELDTLKEnnlktveELNKSKELLNEENQkmeefkkeietlkqAAAQKSQQLSALQEENVKLAEELgrt 1944
Cdd:pfam01576  450 NEAEGKNIKLSKDVSSLES-------QLQDTQELLQEETR--------------QKLNLSTRLRQLEDERNSLQEQL--- 505

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672073054  1945 RDEVTSHQKLEEERSVLNNQLLEMKKR---ESEYRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGE 2017
Cdd:pfam01576  506 EEEEEAKRNVERQLSTLQAQLSDMKKKleeDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQE 581
CLIP1_ZNF pfam16641
CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of ...
 2131-2148 1.90e-04

CLIP1 zinc knuckle; This zinc knuckle domain is found tandemly repeated at the C-terminal of the cytoplasmic linker protein CLIP1 (CLIP170). It forms a complex with the CAP-Gly domain of Dynactin.


Pssm-ID: 465212  Cd Length: 17  Bit Score: 40.14  E-value: 1.90e-04
                           10
                   ....*....|....*...
gi 672073054  2131 RLFCDICDCFDlHDTEDC 2148
Cdd:pfam16641    1 RPYCEICEVFG-HDTEDC 17
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1474-1976 2.04e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 2.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1474 VARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQ--RKKEN 1551
Cdd:COG4717    48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKleKLLQL 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1552 QELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNaelktccceknillrdglNLQEECQKLNEEIREIQQTLMLE 1631
Cdd:COG4717   128 LPLYQELEALEAELAELPERLEELEERLEELRELEEELE------------------ELEAELAELQEELEELLEQLSLA 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1632 KEARAKESESSLyesNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKvvEIIKEKELLSAETAQLAAnIET 1711
Cdd:COG4717   190 TEEELQDLAEEL---EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE--ERLKEARLLLLIAAALLA-LLG 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1712 LKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQdnknllAEKREMMLRNEEVLKEKEKLEESYFVLQK 1791
Cdd:COG4717   264 LGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQ------ALPALEELEEEELEELLAALGLPPDLSPE 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1792 EISQLAQtnshisaDLLEAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDamqimeqmtkektETLASLEDTKQTN 1871
Cdd:COG4717   338 ELLELLD-------RIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDE-------------EELRAALEQAEEY 397

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1872 AKLQSELDTLKENnlktVEELNKSKELLNEENQKmEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEvTSH 1951
Cdd:COG4717   398 QELKEELEELEEQ----LEELLGELEELLEALDE-EELEEELEELEEELEELEEELEELREELAELEAELEQLEED-GEL 471

                         490       500
                  ....*....|....*....|....*
gi 672073054 1952 QKLEEERSVLNNQLLEMKKRESEYR 1976
Cdd:COG4717   472 AELLQELEELKAELRELAEEWAALK 496
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1700-2023 2.24e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 2.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1700 AETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAvtERAEVLQDNKN------LLAEKREMMLRNE 1773
Cdd:TIGR02169  163 AGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA--ERYQALLKEKReyegyeLLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1774 EVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEA--------QSENRTLRKDKSKLTLKIRELETLHSFtAAQTAED 1845
Cdd:TIGR02169  241 AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkikdlgEEEQLRVKEKIGELEAEIASLERSIAE-KERELED 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1846 AMQIMEQMTKEKTETLA-------SLEDTKQTNAKLQSELDtlkennlktveelnKSKELLNEENQKMEEFKKEIETLKQ 1918
Cdd:TIGR02169  320 AEERLAKLEAEIDKLLAeieelerEIEEERKRRDKLTEEYA--------------ELKEELEDLRAELEEVDKEFAETRD 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1919 AAAQKSQQLSALQEENVKLAEELGRTRDEVtshQKLEEERSVLNNQL--LEMKKRESEYR-KDADEEKASLQKSISLTSA 1995
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEEL---QRLSEELADLNAAIagIEAKINELEEEkEDKALEIKKQEWKLEQLAA 462

                          330       340
                   ....*....|....*....|....*...
gi 672073054  1996 LLTEKDAELEKLRNEVTVLRGENASAKS 2023
Cdd:TIGR02169  463 DLSKYEQELYDLKEEYDRVEKELSKLQR 490
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 771-931 2.58e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.92  E-value: 2.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  771 QLLD--LDALRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVNQVKE-- 846
Cdd:COG1579    13 QELDseLDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEye 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  847 TLEKELQTLKEKFASASEEavstqtsMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEK----DEREDQLVKAK 922
Cdd:COG1579    93 ALQKEIESLKRRISDLEDE-------ILELMERIEELEEELAELEAELAELEAELEEKKAELDEElaelEAELEELEAER 165


                  ....*....
gi 672073054  923 EKLENDIAE 931
Cdd:COG1579   166 EELAAKIPP 174
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 788-993 2.74e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.59  E-value: 2.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  788 EIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLNEVN----QVKETLEKELQTLKEKFASAS 863
Cdd:COG3883    24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEaeieERREELGERARALYRSGGSVS 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  864 E-EAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQ 942
Cdd:COG3883   104 YlDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEAL 183

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 672073054  943 LTKMNDELRLKERSVEELQLKLTKANENASLLQKSIGEVTLKAEQSQQEAA 993
Cdd:COG3883   184 LAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAA 234
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 735-899 4.02e-04

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 45.51  E-value: 4.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   735 QEAEIKVKELEVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNAES 814
Cdd:pfam07111   63 QQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDALAVAEKAGQAEAEGLRAALAGAEMVRKNLEEGSQREL 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   815 SKANSITKD-----LQGKELMLTSLQSNlnevnqvKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNM 889
Cdd:pfam07111  143 EEIQRLHQEqlsslTQAHEEALSSLTSK-------AEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLSKTQEELEA 215

                          170
                   ....*....|
gi 672073054   890 LSSELEKLRE 899
Cdd:pfam07111  216 QVTLVESLRK 225
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1740-2129 4.03e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 45.84  E-value: 4.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1740 LRLNHEVAVTERAEVLQDN--KNLLAEKREMMLRNEEVL----KEKEKLEESYFVLQ---KEISQLAQTNSHISADLLEA 1810
Cdd:COG5022   832 LRETEEVEFSLKAEVLIQKfgRSLKAKKRFSLLKKETIYlqsaQRVELAERQLQELKidvKSISSLKLVNLELESEIIEL 911

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1811 QSENRTLRKDKSKLtlkireletlhsftaaqtaedamqimeqmtkeKTETLASLEDTKQTnaklqSELDTLKENNLKTVE 1890
Cdd:COG5022   912 KKSLSSDLIENLEF--------------------------------KTELIARLKKLLNN-----IDLEEGPSIEYVKLP 954

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1891 ELNKskelLNEENQKMEEFKKEIE-TLKQAAAQKSQQLSALQE------ENVKLAEELGRTRDEVTSHQKLEEERSVLNN 1963
Cdd:COG5022   955 ELNK----LHEVESKLKETSEEYEdLLKKSTILVREGNKANSElknfkkELAELSKQYGALQESTKQLKELPVEVAELQS 1030

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1964 qllEMKKRESEYRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLrgENASAKSLHSVVQTLESDKVKlELKVK 2043
Cdd:COG5022  1031 ---ASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLL--DDKQLYQLESTENLLKTINVK-DLEVT 1104

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 2044 NLELQLKENKRQLSSSSG-NTDVQTEEDEraqesqidFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDPNSYDSDDQ 2122
Cdd:COG5022  1105 NRNLVKPANVLQFIVAQMiKLNLLQEISK--------FLSQLVNTLEPVFQKLSVLQLELDGLFWEANLEALPSPPPFAA 1176


                  ....*..
gi 672073054 2123 EKQSKKK 2129
Cdd:COG5022  1177 LSEKRLY 1183
PRK01156 PRK01156
chromosome segregation protein; Provisional
 726-1319 4.65e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 45.66  E-value: 4.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  726 EMEEMLSK--LQEAEI--KVKELEVLQAKYSEQTQVVGHLTSQLSvveeqllDLDALRKANSEGKLEIETLRQQLEGAEK 801
Cdd:PRK01156  139 EMDSLISGdpAQRKKIldEILEINSLERNYDKLKDVIDMLRAEIS-------NIDYLEEKLKSSNLELENIKKQIADDEK 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  802 QIKNLEMERNAESSKANSITKDLQgkelMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAV----STQTSMQDTV 877
Cdd:PRK01156  212 SHSITLKEIERLSIEYNNAMDDYN----NLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNyykeLEERHMKIIN 287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  878 NKLHQKEEQFN-----------------MLSSELEKLREN---LTDMEA---KFKEKDEREDQLVKAKEKLENDIAEIMK 934
Cdd:PRK01156  288 DPVYKNRNYINdyfkykndienkkqilsNIDAEINKYHAIikkLSVLQKdynDYIKKKSRYDDLNNQILELEGYEMDYNS 367

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  935 MSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASLLQKSIGEVTLKAEQ-SQQEAAKKHEEEKKELENKLLELEKK 1013
Cdd:PRK01156  368 YLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDiSSKVSSLNQRIRALRENLDELSRNME 447

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1014 METSHYQCQDLKAKYEKASSETKIKH-EEILQNFQKMLVDTEDKLKAAQEANRDLMQdMEELKSQADKAKSLTY--LLTS 1090
Cdd:PRK01156  448 MLNGQSVCPVCGTTLGEEKSNHIINHyNEKKSRLEEKIREIEIEVKDIDEKIVDLKK-RKEYLESEEINKSINEynKIES 526

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1091 AKKEIEVMSEELRGLKsEKQLfaqEASALKLEKGSLlsKLIEVETKITLLQEDQQKLWSVN-ENLHLEKERISEEKQVAE 1169
Cdd:PRK01156  527 ARADLEDIKIKINELK-DKHD---KYEEIKNRYKSL--KLEDLDSKRTSWLNALAVISLIDiETNRSRSNEIKKQLNDLE 600

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1170 KRYQQEHRDKESLVVEREKLLKEInvtQEELLKMHMEKDSLEASKVSMQVLIEELRFCKDKLMAMSEKaraEKEQLEGQV 1249
Cdd:PRK01156  601 SRLQEIEIGFPDDKSYIDKSIREI---ENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSI---IPDLKEITS 674

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672073054 1250 KKLTAE-NMVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENL 1319
Cdd:PRK01156  675 RINDIEdNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKKIKKAIGDLKRLREAF 745
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1865-1984 5.07e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 45.20  E-value: 5.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1865 EDTKQTN---AKLQSELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQ-LSALQEENVKLAEE 1940
Cdd:PRK00409  513 EDKEKLNeliASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQaIKEAKKEADEIIKE 592

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 672073054 1941 LGRTRDEVTSHQK---LEEERSVLNNQLLEMKKRESEYRKDADEEKA 1984
Cdd:PRK00409  593 LRQLQKGGYASVKaheLIEARKRLNKANEKKEKKKKKQKEKQEELKV 639
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1370-2010 5.34e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 5.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1370 KALRKAEL--DMRQLQTSNTSLTKLLEEIKTCRAITDSECIQllHEKESLAASERALLAEKEELLNENRVITEKLNKHSE 1447
Cdd:COG4913   246 DAREQIELlePIRELAERYAAARERLAELEYLRAALRLWFAQ--RRLELLEAELEELRAELARLEAELERLEARLDALRE 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1448 EVTRLEVSLNE----KITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEatnR 1523
Cdd:COG4913   324 ELDELEAQIRGnggdRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEE---L 400

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1524 RLAVQEKVKLLGNIDALKKELQQRKKENQELASSKcdlSLMLKEAQTAKKNLEkEHTSMmqAKEDLN--AELktcccekn 1601
Cdd:COG4913   401 EALEEALAEAEAALRDLRRELRELEAEIASLERRK---SNIPARLLALRDALA-EALGL--DEAELPfvGEL-------- 466

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1602 illrdgLNLQEECQK----LNEEIREIQQTLMLEKE--ARAkeseSSLYESNKLHGRIVLleeeiqglrtcseqlqtenf 1675
Cdd:COG4913   467 ------IEVRPEEERwrgaIERVLGGFALTLLVPPEhyAAA----LRWVNRLHLRGRLVY-------------------- 516

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1676 tltqektnseQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKIlDDLRlNHEVAVTeRAEVL 1755
Cdd:COG4913   517 ----------ERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRFDYVCVDSP-EELR-RHPRAIT-RAGQV 583

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1756 QDNKNLLAEKREMMLRNEEVL--KEKEKLEEsyfvLQKEISQLAQtnshisaDLLEAQSENRTLRKDKSKLTLKIRELET 1833
Cdd:COG4913   584 KGNGTRHEKDDRRRIRSRYVLgfDNRAKLAA----LEAELAELEE-------ELAEAEERLEALEAELDALQERREALQR 652

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1834 LHSFTAAQtaEDAMQIMEQMTkEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEI 1913
Cdd:COG4913   653 LAEYSWDE--IDVASAEREIA-ELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEEL 729

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1914 ETLKQAAAQKSQQLSALQEENV-KLAEELGRTRDEVTSHQKLEEERSVLNNQLL----EMKKRESEYRKDADEEKASLQK 1988
Cdd:COG4913   730 DELQDRLEAAEDLARLELRALLeERFAAALGDAVERELRENLEERIDALRARLNraeeELERAMRAFNREWPAETADLDA 809

                         650       660
                  ....*....|....*....|..
gi 672073054 1989 SIsltsALLTEKDAELEKLRNE 2010
Cdd:COG4913   810 DL----ESLPEYLALLDRLEED 827
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 461-666 5.71e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 5.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  461 SEDPENTQTKLE--HARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLE----- 533
Cdd:COG4942    19 ADAAAEAEAELEqlQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAelrae 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  534 ----------------------------SSKPPGDVDMSLSLLQEISALQEKLEVTHTDHQNEVTSLKdhfgtreemfqK 585
Cdd:COG4942    99 leaqkeelaellralyrlgrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALR-----------A 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  586 EIKALHAATEKLSKENESLRSKLDHANKENSDVIAlwksKLETAIASHQQAMEELKvsfskgigtdsAEFAELKTQIERL 665
Cdd:COG4942   168 ELEAERAELEALLAELEEERAALEALKAERQKLLA----RLEKELAELAAELAELQ-----------QEAEELEALIARL 232


                  .
gi 672073054  666 R 666
Cdd:COG4942   233 E 233
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1543-2105 6.04e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 45.17  E-value: 6.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1543 ELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHtsmMQAKEDLNAELKTCCCEKNILLRdglnLQEECQKLNEEIR 1622
Cdd:pfam01576    6 EMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEK---NALQEQLQAETELCAEAEEMRAR----LAARKQELEEILH 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1623 EIQQTLMLEKEarakESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAET 1702
Cdd:pfam01576   79 ELESRLEEEEE----RSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKER 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1703 AQLAANIETLKSDFAalsksklELQELHSCLTKilddLRLNHEVAVTERAEVLQDNKNLlaeKREMMLRNEEVLKEKEKL 1782
Cdd:pfam01576  155 KLLEERISEFTSNLA-------EEEEKAKSLSK----LKNKHEAMISDLEERLKKEEKG---RQELEKAKRKLEGESTDL 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1783 EESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLHS-------------FTAAQTAEDAMQI 1849
Cdd:pfam01576  221 QEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISelqedleseraarNKAEKQRRDLGEE 300

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1850 MEQMTKEKTETLASLEDTKQTNAKLQSELDTLKennlKTVEELNKS-----KELLNEENQKMEEFKKEIETLKQAAAQKS 1924
Cdd:pfam01576  301 LEALKTELEDTLDTTAAQQELRSKREQEVTELK----KALEEETRSheaqlQEMRQKHTQALEELTEQLEQAKRNKANLE 376

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1925 QQLSALQEENVKLAEELgrtRDEVTSHQKLEEERSVLNNQLLEMKKRESE---YRKDADEEKASLQKSISLTSALLTEKD 2001
Cdd:pfam01576  377 KAKQALESENAELQAEL---RTLQQAKQDSEHKRKKLEGQLQELQARLSEserQRAELAEKLSKLQSELESVSSLLNEAE 453

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  2002 AELEKLRNEVTVLRGENASAKSLhsvVQTLESDKVKLELKVKNLELQLKENKRQLSsssgntdvQTEEDERAQESQIDFL 2081
Cdd:pfam01576  454 GKNIKLSKDVSSLESQLQDTQEL---LQEETRQKLNLSTRLRQLEDERNSLQEQLE--------EEEEAKRNVERQLSTL 522

                          570       580
                   ....*....|....*....|....
gi 672073054  2082 NSVIVDLQRKNQDLKMKVEMMSEA 2105
Cdd:pfam01576  523 QAQLSDMKKKLEEDAGTLEALEEG 546
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
659-1335 6.90e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 6.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  659 KTQIERLRLDYQHEIESLQS----KQDSERSAHAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEDQhLVEMEEMLSKL 734
Cdd:PRK02224  175 RLGVERVLSDQRGSLDQLKAqieeKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEV-LEEHEERREEL 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  735 QEAEIKVKEL-EVLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEGAEKQIKNLEmERNAE 813
Cdd:PRK02224  254 ETLEAEIEDLrETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELR-DRLEE 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  814 SSkansitkdlqgkelmlTSLQSNLNEVnqvkETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSE 893
Cdd:PRK02224  333 CR----------------VAAQAHNEEA----ESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEE 392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  894 LEKLRENLTDMEAKFKEKDEREDQLVKAKEKLENDIAEimkmsgdnssqltkmndeLRLKERSVEElqlkltKANENASL 973
Cdd:PRK02224  393 IEELRERFGDAPVDLGNAEDFLEELREERDELREREAE------------------LEATLRTARE------RVEEAEAL 448

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  974 LQKSigevtlKAEQSQQEAAKKHEEEKKElenkllelekkmetshyQCQDLKAKYEKASSETKIKHEEILQNFqkmlvdt 1053
Cdd:PRK02224  449 LEAG------KCPECGQPVEGSPHVETIE-----------------EDRERVEELEAELEDLEEEVEEVEERL------- 498

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1054 eDKLKAAQEANRdlmqdmeELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQE-------ASALKLEKGSL 1126
Cdd:PRK02224  499 -ERAEDLVEAED-------RIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEaeekreaAAEAEEEAEEA 570

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1127 LSKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEEKQVAEKRYQQEHRDKESlvverekllkeinvtQEELLKMHME 1206
Cdd:PRK02224  571 REEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDER---------------RERLAEKRER 635

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1207 KDSLEASkvsmqvlIEELRFckdklmamsEKARAEKEQLEGQVKKLTAENMVLVKDKDDVIQKLQSAYEELvkdqkalvQ 1286
Cdd:PRK02224  636 KRELEAE-------FDEARI---------EEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL--------E 691

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*....
gi 672073054 1287 EIEDLTTEKKSAAEKQMNLDntclTLKAERENLLQSNRDLQFEkdtLRQ 1335
Cdd:PRK02224  692 ELEELRERREALENRVEALE----ALYDEAEELESMYGDLRAE---LRQ 733
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1235-1916 9.14e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 9.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1235 SEKARAEKEQLEgqVKKLTAENMVLVKDKDDVIQKLQSAYEELVKdqkalvqEIEDLTTEKKSAAEKQMNLDNTCLTLKA 1314
Cdd:TIGR04523  124 VELNKLEKQKKE--NKKNIDKFLTEIKKKEKELEKLNNKYNDLKK-------QKEELENELNLLEKEKLNIQKNIDKIKN 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1315 ERENLLQSNRDLQfekdTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLE 1394
Cdd:TIGR04523  195 KLLKLELLLSNLK----KKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1395 EiktcraitdseciqllheKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRLEV-----SLNEKITYLTSEKEM 1469
Cdd:TIGR04523  271 E------------------KQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELkselkNQEKKLEEIQNQISQ 332

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1470 ACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEatnrrlaVQEKVKLLGNIDALKKELQQRKK 1549
Cdd:TIGR04523  333 NNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSY-------KQEIKNLESQINDLESKIQNQEK 405

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1550 ENQELASSkcdlslmLKEAQTAKKNLEKEHTSMMQAKEDLNAELKtccceknillrdglNLQEECQKLNEEIREIQQTLM 1629
Cdd:TIGR04523  406 LNQQKDEQ-------IKKLQQEKELLEKEIERLKETIIKNNSEIK--------------DLTNQDSVKELIIKNLDNTRE 464

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1630 LEKEarakesesslyesnklhgRIVLLEEEIQGLRTCSEQLQtenftltQEKTNSEQKVVEIIKEKELLSAETAQLAANI 1709
Cdd:TIGR04523  465 SLET------------------QLKVLSRSINKIKQNLEQKQ-------KELKSKEKELKKLNEEKKELEEKVKDLTKKI 519

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1710 ETLKSDFAALSKSKLEL-QELHSCLTKIL-DDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEESYF 1787
Cdd:TIGR04523  520 SSLKEKIEKLESEKKEKeSKISDLEDELNkDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKK 599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1788 VLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLHSFTAaQTAEDAMQIMEQMTKEKTETLASLEDT 1867
Cdd:TIGR04523  600 DLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIK-ETIKEIRNKWPEIIKKIKESKTKIDDI 678

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 672073054  1868 KQTNAKLQSELDTLKENNLKT------VEELNKSKELLNEENQKMEEFKKEIETL 1916
Cdd:TIGR04523  679 IELMKDWLKELSLHYKKYITRmirikdLPKLEEKYKEIEKELKKLDEFSKELENI 733
HEC1 COG5185
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ...
 1883-2129 9.49e-04

Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444066 [Multi-domain]  Cd Length: 594  Bit Score: 44.18  E-value: 9.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1883 ENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAA----AQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEER 1958
Cdd:COG5185   232 EEALKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKlgenAESSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKAT 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1959 SVLNNQLLEMKKRES--EYRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKV 2036
Cdd:COG5185   312 ESLEEQLAAAEAEQEleESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKSSEELDSFKDTIESTKE 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 2037 KLELKVKNLELQLKENKRQLSSSSGNTDVQTEEDERaqesQIDFLNSVIVDLQRKNQDL-KMKVEMMSEAALNGNGEDPN 2115
Cdd:COG5185   392 SLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQR----QIEQATSSNEEVSKLLNELiSELNKVMREADEESQSRLEE 467

                         250
                  ....*....|....
gi 672073054 2116 SYDSDDQEKQSKKK 2129
Cdd:COG5185   468 AYDEINRSVRSKKE 481
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1368-2129 1.09e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.27  E-value: 1.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1368 ATKALRKAELDMRQ-LQTSNTSLTKLLEEIKTCRAITDSeciqlLHEKESLAASERALLAEKEELLNEnrvITEKLNKHS 1446
Cdd:TIGR00606  187 ALETLRQVRQTQGQkVQEHQMELKYLKQYKEKACEIRDQ-----ITSKEAQLESSREIVKSYENELDP---LKNRLKEIE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1447 EEVTRLEVSLNEKITYLTSEKEMACQKvarlKKQQDSLLKEKSALEVQNGDLLADRESSIKAIG----DLKRKYEQEATN 1522
Cdd:TIGR00606  259 HNLSKIMKLDNEIKALKSRKKQMEKDN----SELELKMEKVFQGTDEQLNDLYHNHQRTVREKErelvDCQRELEKLNKE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1523 RRLAVQEKVKLLGNIDALkkelqQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAK-------EDLNAELKT 1595
Cdd:TIGR00606  335 RRLLNQEKTELLVEQGRL-----QLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKnfhtlviERQEDEAKT 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1596 CCCEKNILLRDGLNLQEECQKLNEEIREIQQTLMLEKEARAKESES---SLYESNKLHG---RIVLLEEE-IQGLRTCSE 1668
Cdd:TIGR00606  410 AAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEElkfVIKELQQLEGssdRILELDQElRKAERELSK 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1669 QLQTENF-TLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLrlNHEVA 1747
Cdd:TIGR00606  490 AEKNSLTeTLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDEL--TSLLG 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1748 VTERAEVLQDN-KNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEA---QSENRTLRKDKSK 1823
Cdd:TIGR00606  568 YFPNKKQLEDWlHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVcgsQDEESDLERLKEE 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1824 LTLKIRELETLHSFTAAQTaedamQIMEQMTKEKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELNKSKELLNEEN 1903
Cdd:TIGR00606  648 IEKSSKQRAMLAGATAVYS-----QFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1904 QKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEE--------------ERSVLNNQLLEMK 1969
Cdd:TIGR00606  723 KRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGtimpeeesakvcltDVTIMERFQMELK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1970 KRESEYRKDADEEKAS-LQKSISLTSALLTEKDAELEKLRNEVTVLRG----ENASAKSLHSVVQTLESDKVKLELKVKN 2044
Cdd:TIGR00606  803 DVERKIAQQAAKLQGSdLDRTVQQVNQEKQEKQHELDTVVSKIELNRKliqdQQEQIQHLKSKTNELKSEKLQIGTNLQR 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  2045 ---LELQLKENKRQLSSSSGNTDVQTEEDERAQESQIDFLNSVIVDLQRKNQDLK---MKVEMMSEAALN--GNGEDPNS 2116
Cdd:TIGR00606  883 rqqFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKkaqDKVNDIKEKVKNihGYMKDIEN 962

                          810
                   ....*....|...
gi 672073054  2117 YDSDDQEKQSKKK 2129
Cdd:TIGR00606  963 KIQDGKDDYLKQK 975
PTZ00121 PTZ00121
MAEBL; Provisional
 1473-2105 1.20e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1473 KVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAigDLKRKYEQEatnRRLAVQEKVKLLGNIDALKKELQQRKKENQ 1552
Cdd:PTZ00121 1167 EEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKA--EAARKAEEE---RKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1553 ELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELKTCCCEKNillrdglnlQEECQKLNEEIREIQQTLMLEK 1632
Cdd:PTZ00121 1242 AKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKK---------KADEAKKAEEKKKADEAKKKAE 1312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1633 EARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAA----N 1708
Cdd:PTZ00121 1313 EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAeekkK 1392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1709 IETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREMMLRNEEVLKEKEKLEEsyfv 1788
Cdd:PTZ00121 1393 ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEE---- 1468

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1789 lqKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTK 1868
Cdd:PTZ00121 1469 --AKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKK 1546

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1869 QTNAKLQSElDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEV 1948
Cdd:PTZ00121 1547 KADELKKAE-ELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL 1625

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1949 TSHQKLEEERSVLNNQLLEMKKRESEYRKDADEEKASLQKsisltsallTEKDAELEKLRNEvtVLRGENASAKSLHSVV 2028
Cdd:PTZ00121 1626 KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE---------EAKKAEEDKKKAE--EAKKAEEDEKKAAEAL 1694

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672073054 2029 QTLESDKVKLElKVKNLELQLKENKRQLSSSSGNTDVQTEEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSEA 2105
Cdd:PTZ00121 1695 KKEAEEAKKAE-ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA 1770
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1892-2095 1.31e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1892 LNKSKELLNEENQKMEEF-KKEIETLKQAAAQKSQQLSALQEEN--VKLAEELGRTRDEVTShqkLEEERSVLNNQLLEM 1968
Cdd:COG3206   162 LEQNLELRREEARKALEFlEEQLPELRKELEEAEAALEEFRQKNglVDLSEEAKLLLQQLSE---LESQLAEARAELAEA 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1969 KKRESEYRKDADEEKASLqkSISLTSALLTEKDAELEKLRNEVTVLRgenASAKSLHSVVQTLESdkvklelKVKNLELQ 2048
Cdd:COG3206   239 EARLAALRAQLGSGPDAL--PELLQSPVIQQLRAQLAELEAELAELS---ARYTPNHPDVIALRA-------QIAALRAQ 306

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 672073054 2049 LKENKRQLSSSSGNTDVQTEEDERAQESQIDFLNSVIVDLQRKNQDL 2095
Cdd:COG3206   307 LQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAEL 353
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 670-1553 1.33e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.27  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   670 QHEIESLQSKQDSERSAHAKEM----ESMKAKLMKIIKEKEDSLEAVKARLDtaedqhlvEMEEMLSKLQEAEIKVKELE 745
Cdd:TIGR00606  204 EHQMELKYLKQYKEKACEIRDQitskEAQLESSREIVKSYENELDPLKNRLK--------EIEHNLSKIMKLDNEIKALK 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   746 VLQAKY-SEQTQVVGHLTSQLSVVEEQLLDLDALRKANSEGK--------LEIETLRQQLEGAEKQIKNLEMERNAESSK 816
Cdd:TIGR00606  276 SRKKQMeKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKerelvdcqRELEKLNKERRLLNQEKTELLVEQGRLQLQ 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   817 ANSITKDLQGKELMLTSLQSNLnEVNQVKETLEKELQT---LKEKFASASEEAVSTQTSMQDTVNKLHQKEEQfnmlsse 893
Cdd:TIGR00606  356 ADRHQEHIRARDSLIQSLATRL-ELDGFERGPFSERQIknfHTLVIERQEDEAKTAAQLCADLQSKERLKQEQ------- 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   894 LEKLRENLTDMEAKFKEKDERedqLVKAKEKLENDIAEIMKMSGdNSSQLTKMNDELRLKERsveelqlKLTKANENASL 973
Cdd:TIGR00606  428 ADEIRDEKKGLGRTIELKKEI---LEKKQEELKFVIKELQQLEG-SSDRILELDQELRKAER-------ELSKAEKNSLT 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   974 LQKSIGEVTLKAEQSQQEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEILQNF--QKMLV 1051
Cdd:TIGR00606  497 ETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFpnKKQLE 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1052 DTEDKLKAAQEANRDLMQDME-ELKSQADKAKSLTYLLTSAKKEIEVMSEEL------RGLKSEKQLFAQEASALKLEKG 1124
Cdd:TIGR00606  577 DWLHSKSKEINQTRDRLAKLNkELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKSSKQRA 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1125 SLLSKLIEVETKITLLQEDQQKLWSVNENLHLEKERISEekqvAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKMh 1204
Cdd:TIGR00606  657 MLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQE----FISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGL- 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1205 mekdsLEASKVSMQVLIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKD-----DVIQKLQSAYEELVK 1279
Cdd:TIGR00606  732 -----APGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVcltdvTIMERFQMELKDVER 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1280 DQKALVQEIE------DLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQ-GQEKLSASlEATLQVKQ 1352
Cdd:TIGR00606  807 KIAQQAAKLQgsdldrTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNElKSEKLQIG-TNLQRRQQ 885

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1353 L------LSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIKTCRAITDSECIQLLHEKESLAAS-ERALL 1425
Cdd:TIGR00606  886 FeeqlveLSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDiENKIQ 965

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1426 AEKEELLNENRVITEKLNKHSEEVTRLEVSLNEKITYLTSEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESS 1505
Cdd:TIGR00606  966 DGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMG 1045

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*...
gi 672073054  1506 IKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKENQE 1553
Cdd:TIGR00606 1046 QMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELRE 1093
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1055-1484 1.41e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1055 DKLKAAQEANRDLMQDMEELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFA--QEASALKLEKGSLLSKLIE 1132
Cdd:COG4717    71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPERLEE 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1133 VETKITLLQEDQQKLWSVNENLHLEKERISEEKQ----VAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKMHMEKD 1208
Cdd:COG4717   151 LEERLEELRELEEELEELEAELAELQEELEELLEqlslATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELE 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1209 SLEASKVSMQvLIEELRFCKDKLMAMSEKARAEKEQLEGQVKKLTAENMVLVkdkddVIQKLQSAYEELVKDQKALVQEI 1288
Cdd:COG4717   231 QLENELEAAA-LEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFL-----VLGLLALLFLLLAREKASLGKEA 304

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1289 EDLTTEKKSAAEKQMNLDNTCLTLKAERENLLQSNRDLQFEKDTLRQGQEKLsASLEATLQVKQLLSTEAETLRTQLDCA 1368
Cdd:COG4717   305 EELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREA-EELEEELQLEELEQEIAALLAEAGVED 383

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1369 TKALRKAELDMRQLQtsntsltKLLEEIKTCRAITDSECIQLLHEKEslAASERALLAEKEELLNENRVITEKLNKHSEE 1448
Cdd:COG4717   384 EEELRAALEQAEEYQ-------ELKEELEELEEQLEELLGELEELLE--ALDEEELEEELEELEEELEELEEELEELREE 454

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|.
gi 672073054 1449 VTRLEVSLN-----EKITYLTSEKEMACQKVARLKKQQDSL 1484
Cdd:COG4717   455 LAELEAELEqleedGELAELLQELEELKAELRELAEEWAAL 495
FPP pfam05911
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ...
 760-931 1.48e-03

Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.


Pssm-ID: 461778 [Multi-domain]  Cd Length: 859  Bit Score: 43.90  E-value: 1.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   760 HLTSQLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQSNLN 839
Cdd:pfam05911  654 SEIDNLSSDPEIPSDGPLVSGSNDLKTEENKRLKEEFEQLKSEKENLEVELASCTENLESTKSQLQESEQLIAELRSELA 733

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   840 EVNQVKETLEKELQTLKEkfasaSEEAVSTQTSMQDT-VNKLHQKeeqFNMLSSELEKLRENLTDMEAKFKEKDEREdQL 918
Cdd:pfam05911  734 SLKESNSLAETQLKCMAE-----SYEDLETRLTELEAeLNELRQK---FEALEVELEEEKNCHEELEAKCLELQEQL-ER 804

                          170
                   ....*....|...
gi 672073054   919 VKAKEKLENDIAE 931
Cdd:pfam05911  805 NEKKESSNCDADQ 817
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1238-1452 1.56e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1238 ARAEKEQLEGQVKKLTAEnmvlVKDKDDVIQKLQSAYEELvKDQKALVQEIEDLTTEKKSAAEKQMNLDNtcltLKAERE 1317
Cdd:COG4913   608 NRAKLAALEAELAELEEE----LAEAEERLEALEAELDAL-QERREALQRLAEYSWDEIDVASAEREIAE----LEAELE 678

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1318 NLLQSNRDLqfekdtlrqgqEKLSASLEAtlqvkqlLSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIK 1397
Cdd:COG4913   679 RLDASSDDL-----------AALEEQLEE-------LEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAE 740

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 672073054 1398 TCRAITDSECIQLLHEKESLAASERALlaeKEELLNENRVITEKLNKHSEEVTRL 1452
Cdd:COG4913   741 DLARLELRALLEERFAAALGDAVEREL---RENLEERIDALRARLNRAEEELERA 792
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1185-1719 1.59e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 1.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1185 EREKLLKEINVTQEELLKMHMEKDSLEASKVSMQVLIEELRFckDKLMAMSEKARAEKEQLEGQVKKLTAEnmvlVKDKD 1264
Cdd:COG4913   249 EQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRL--ELLEAELEELRAELARLEAELERLEAR----LDALR 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1265 DVIQKLQSAYEELVKDQKA-LVQEIEDLTTEKKSAAEKQMNLDNTCLTLKAERENllqsnrdlqfEKDTLRQGQEKLSAS 1343
Cdd:COG4913   323 EELDELEAQIRGNGGDRLEqLEREIERLERELEERERRRARLEALLAALGLPLPA----------SAEEFAALRAEAAAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1344 LEATLQVKQLLSTEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKLLEEIKT--CRAITDS--------ECIQLLHE 1413
Cdd:COG4913   393 LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDalAEALGLDeaelpfvgELIEVRPE 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1414 KES-LAASERAL-------------LAEKEELLNEN----RVITEKLNKHSEEVTRLEV---SLNEKITYLTS------E 1466
Cdd:COG4913   473 EERwRGAIERVLggfaltllvppehYAAALRWVNRLhlrgRLVYERVRTGLPDPERPRLdpdSLAGKLDFKPHpfrawlE 552

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1467 KEMA-------CQKVARLKKQQDSLLKE-------------------------------KSALEVQNGDLLADRESSIKA 1508
Cdd:COG4913   553 AELGrrfdyvcVDSPEELRRHPRAITRAgqvkgngtrhekddrrrirsryvlgfdnrakLAALEAELAELEEELAEAEER 632

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1509 IGDLKRkyEQEATNRRLAVQEKVKLLG----NIDALKKELQQRKKENQELASSKCDLSLM---LKEAQTAKKNLEKEHTS 1581
Cdd:COG4913   633 LEALEA--ELDALQERREALQRLAEYSwdeiDVASAEREIAELEAELERLDASSDDLAALeeqLEELEAELEELEEELDE 710

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1582 MMQAKEDLNAELKtccceknillrdglNLQEECQKLNEEIREIQQTLMLEKEARAKEsesslyesnklhgrivLLEEEIQ 1661
Cdd:COG4913   711 LKGEIGRLEKELE--------------QAEEELDELQDRLEAAEDLARLELRALLEE----------------RFAAALG 760

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672073054 1662 G--LRTCSEQLQTENFTLTQEKTNSEQKVVEIIKE-KELLSAETAQLAANIETLkSDFAAL 1719
Cdd:COG4913   761 DavERELRENLEERIDALRARLNRAEEELERAMRAfNREWPAETADLDADLESL-PEYLAL 820
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
354-781 1.76e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  354 EALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHvlELEAKMDQLRTMVEAADREKVELLNQLEEE 433
Cdd:COG4717    81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL--PLYQELEALEAELAELPERLEELEERLEEL 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  434 KRKVEDLQFRVEEESITKGDLEQKSQisEDPENTQTKLEHA--RIKELEQSLLFEKTKADKLQRELEDTR--VATVSEKS 509
Cdd:COG4717   159 RELEEELEELEAELAELQEELEELLE--QLSLATEEELQDLaeELEELQQRLAELEEELEEAQEELEELEeeLEQLENEL 236

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  510 RIMELEKDL-----------ALRVQEVAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEVTHTDHQNEVTSLKDHFGT 578
Cdd:COG4717   237 EAAALEERLkearlllliaaALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEEL 316

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  579 REEMFQKEIKALHAATEKLSKENESLRSKLDHANKENSDVIALWKSkletaiASHQQAMEELKVSFSKGIGTDSAEFAEL 658
Cdd:COG4717   317 EEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE------LQLEELEQEIAALLAEAGVEDEEELRAA 390

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  659 KTQIERLRlDYQHEIESLQSKQDSERSAHAKEMEsmkaklmkiiKEKEDSLEAVKARLDTAEDQHLVEMEEMLSKLQEAE 738
Cdd:COG4717   391 LEQAEEYQ-ELKEELEELEEQLEELLGELEELLE----------ALDEEELEEELEELEEELEELEEELEELREELAELE 459

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 672073054  739 IKVKELEvLQAKYSEQTQVVGHLTSQLSVVEEQLLDLDALRKA 781
Cdd:COG4717   460 AELEQLE-EDGELAELLQELEELKAELRELAEEWAALKLALEL 501
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1178-1466 1.94e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 43.35  E-value: 1.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1178 DKESLVVEREKLLKEINVtqeelLKMHMEKdsleaskvsmqvlieelrfcKDKLMAMSEKARAEKEQLEGQVKKLTAENM 1257
Cdd:PLN02939  157 DLEKILTEKEALQGKINI-----LEMRLSE--------------------TDARIKLAAQEKIHVEILEEQLEKLRNELL 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1258 VLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKqmnlDNTCLTLKAERENLLQSNRDLQFekdTLRQGQ 1337
Cdd:PLN02939  212 IRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAET----EERVFKLEKERSLLDASLRELES---KFIVAQ 284

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1338 EKLSASleATLQVKQLLStEAETLRTQLDCATKALRKAELDMRQLQTSNTSLTKL---LEEIKTCRaiTDSECIQLLHEK 1414
Cdd:PLN02939  285 EDVSKL--SPLQYDCWWE-KVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLeasLKEANVSK--FSSYKVELLQQK 359

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 672073054 1415 esLAASERALLAEKEELLNENRV-------ITEKLNKHSEEVTRLevSLNEKITYLTSE 1466
Cdd:PLN02939  360 --LKLLEERLQASDHEIHSYIQLyqesikeFQDTLSKLKEESKKR--SLEHPADDMPSE 414
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
846-964 2.24e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 42.92  E-value: 2.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  846 ETLEKELQTLKEKfaSASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDER----EDQLVKA 921
Cdd:COG2433   376 LSIEEALEELIEK--ELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERierlERELSEA 453

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 672073054  922 KEKLENDI---AEIMKMSGDNsSQLTKmndELRLKERSVEELQLKL 964
Cdd:COG2433   454 RSEERREIrkdREISRLDREI-ERLER---ELEEERERIEELKRKL 495
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1465-1919 2.44e-03

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 43.19  E-value: 2.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1465 SEKEMACQKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKEL 1544
Cdd:pfam05557   65 AEAEEALREQAELNRLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLL 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1545 QQRKKENQELASSKCDLSLMLKEAQTAKKNLEKEHTSMMQAKE-------------DLNAELKTCCcEKNILLRDglnLQ 1611
Cdd:pfam05557  145 KAKASEAEQLRQNLEKQQSSLAEAEQRIKELEFEIQSQEQDSEivknskselaripELEKELERLR-EHNKHLNE---NI 220

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1612 EECQKLNEEIREIQQTLMLEKEARAK---------ESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKT 1682
Cdd:pfam05557  221 ENKLLLKEEVEDLKRKLEREEKYREEaatlelekeKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQREIVLKEENS 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1683 NSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHE----------------V 1746
Cdd:pfam05557  301 SLTSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILEsydkeltmsnyspqllE 380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1747 AVTERAEVLQDNKNLLAEKREMMLRNEE-----------------VLKEKEKLEESYFVlQKEISQLAQTNSHISADL-- 1807
Cdd:pfam05557  381 RIEEAEDMTQKMQAHNEEMEAQLSVAEEelggykqqaqtlerelqALRQQESLADPSYS-KEEVDSLRRKLETLELERqr 459

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1808 -------LEAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSELDT 1880
Cdd:pfam05557  460 lreqkneLEMELERRCLQGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTST 539

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|
gi 672073054  1881 LkenNLKTVEELNKSKELLNEENQKMEE-FKKEIETLKQA 1919
Cdd:pfam05557  540 M---NFKEVLDLRKELESAELKNQRLKEvFQAKIQEFRDV 576
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1152-1626 2.48e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 2.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1152 ENLHLEKERISEEKQVAEKRYQQEHRDKESLVVEREKLLKEINVTQEELLKMHMEKDSLEASKVSMQVLIEELRFCKDKL 1231
Cdd:COG4717    49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1232 MAMSEKARAEKE--QLEGQVKKLtaenmvlvKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNldntc 1309
Cdd:COG4717   129 PLYQELEALEAElaELPERLEEL--------EERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ----- 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1310 lTLKAERENLLQSNRDLQFEKDTLRQGQEKLSASLEAtLQVKQLLSTEAETLRtqldcATKALRKAELDMRQLQTSNTSL 1389
Cdd:COG4717   196 -DLAEELEELQQRLAELEEELEEAQEELEELEEELEQ-LENELEAAALEERLK-----EARLLLLIAAALLALLGLGGSL 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1390 TKLLEEIKTCRAITDSECIQLLHEKESLAASERALLAEKEELLNENRVITEKLNKHSEEVTRLEVSLNEKITYLTSEKEM 1469
Cdd:COG4717   269 LSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEE 348

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1470 ACQKVARLKKQQDSLLKEKSALEVQNgdLLAdrESSIKAIGDLKRKYEQeatnrrlaVQEKVKLLGNIDALKKELQQRKK 1549
Cdd:COG4717   349 LQELLREAEELEEELQLEELEQEIAA--LLA--EAGVEDEEELRAALEQ--------AEEYQELKEELEELEEQLEELLG 416

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1550 ENQELAS--SKCDLSLMLKEAQTAKKNLEKEHTSMMQAKEDLNAELKTcccekniLLRDGL--NLQEECQKLNEEIREIQ 1625
Cdd:COG4717   417 ELEELLEalDEEELEEELEELEEELEELEEELEELREELAELEAELEQ-------LEEDGElaELLQELEELKAELRELA 489


                  .
gi 672073054 1626 Q 1626
Cdd:COG4717   490 E 490
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 375-977 2.53e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 2.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   375 AEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVE---AADREKVELLNQLEEEKRKVEDLQFRVEEEsitk 451
Cdd:pfam01576   12 EELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETElcaEAEEMRARLAARKQELEEILHELESRLEEE---- 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   452 gdlEQKSQISEdpenTQTKLEHARIKELEQSLLFEKTKADKLQREledtrvaTVSEKSRIMELEKDLALRvqevaelrrr 531
Cdd:pfam01576   88 ---EERSQQLQ----NEKKKMQQHIQDLEEQLDEEEAARQKLQLE-------KVTTEAKIKKLEEDILLL---------- 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   532 lesskppgdVDMSLSLLQEISALQEKLEVTHTDHQNEVTSLKD--HFGTREEMFQKEIKALHAATEKLSKENESLRSKLD 609
Cdd:pfam01576  144 ---------EDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSlsKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLE 214

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   610 HANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKgigtdSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAhak 689
Cdd:pfam01576  215 GESTDLQEQIAELQAQIAELRAQLAKKEEELQAALAR-----LEEETAQKNNALKKIRELEAQISELQEDLESERAA--- 286

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   690 emesmKAKLMKIIKEKEDSLEAVKARLD-----TAEDQHLVEMEE----MLSKLQEAEIKVKELEVLQAKySEQTQVVGH 760
Cdd:pfam01576  287 -----RNKAEKQRRDLGEELEALKTELEdtldtTAAQQELRSKREqevtELKKALEEETRSHEAQLQEMR-QKHTQALEE 360

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   761 LTSQLSVVEEQLLDLD----ALRKANSEGKLEIETLRQQLEGAEKQIKNLEMERNAESSKANSITKDLQGKELMLTSLQS 836
Cdd:pfam01576  361 LTEQLEQAKRNKANLEkakqALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQS 440

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   837 NLNEVNQVKETLEKelqtlkeKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDERED 916
Cdd:pfam01576  441 ELESVSSLLNEAEG-------KNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKR 513

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 672073054   917 QLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASLLQKS 977
Cdd:pfam01576  514 NVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKT 574
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1537-2039 2.76e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.11  E-value: 2.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1537 IDALKKELQQRKKENQELASSKCDLSLMLKEAQTAKKNLEkehtSMMQAKEDLNAELKTCCCEKNILLRDGLNLQEECQK 1616
Cdd:PRK02224  215 LAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE----TLEAEIEDLRETIAETEREREELAEEVRDLRERLEE 290

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1617 LNEEIREIQQTLMLEkearAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKE 1696
Cdd:PRK02224  291 LEEERDDLLAEAGLD----DADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAA 366

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1697 LLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKREMmlrnEEVL 1776
Cdd:PRK02224  367 ELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA----RERV 442

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1777 KEKEKLEESYFVlqKEISQLAQTNSHISAdLLEAQSENRTLRKDKSKLTLKIRELETLHsftaaQTAEDAmqimeqmtKE 1856
Cdd:PRK02224  443 EEAEALLEAGKC--PECGQPVEGSPHVET-IEEDRERVEELEAELEDLEEEVEEVEERL-----ERAEDL--------VE 506

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1857 KTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVK 1936
Cdd:PRK02224  507 AEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKE 586

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1937 LAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEYR----------------------KDADEEKASLQKSISLTS 1994
Cdd:PRK02224  587 RIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRerlaekrerkreleaefdeariEEAREDKERAEEYLEQVE 666

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*
gi 672073054 1995 ALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLE 2039
Cdd:PRK02224  667 EKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEALE 711
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1856-2079 2.81e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 2.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1856 EKTETLASLEDTKQTNAKLQSELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQK----SQQLSALQ 1931
Cdd:COG3883    17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERreelGERARALY 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1932 E--------ENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEYRKDADEEKASLQKSIsltsALLTEKDAE 2003
Cdd:COG3883    97 RsggsvsylDVLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALK----AELEAAKAE 172

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672073054 2004 LEKLRNEVTVLrgenasakslhsvVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDVQTEEDERAQESQID 2079
Cdd:COG3883   173 LEAQQAEQEAL-------------LAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1472-1721 2.85e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1472 QKVARLKKQQDSLLKEKSALEVQNGDLLADRESSIKAIGDLKRKYEQEATNRRLAVQEKVKLLGNIDALKKELQQRKKEn 1551
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE- 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1552 qelasskcdLSLMLKEAQtakKNLEKEHTSMMQAKEDLNAelktcccekniLLRDGLNLQEECQKLNEEIREIQQTLmle 1631
Cdd:COG4942   106 ---------LAELLRALY---RLGRQPPLALLLSPEDFLD-----------AVRRLQYLKYLAPARREQAEELRADL--- 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1632 kearakesesslyesNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIET 1711
Cdd:COG4942   160 ---------------AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224

                         250
                  ....*....|
gi 672073054 1712 LKSDFAALSK 1721
Cdd:COG4942   225 LEALIARLEA 234
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 1806-1960 2.86e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 42.68  E-value: 2.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1806 DLLEAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSEldTLKENN 1885
Cdd:pfam05262  202 DLKERESQEDAKRAQQLKEELDKKQIDADKAQQKADFAQDNADKQRDEVRQKQQEAKNLPKPADTSSPKEDK--QVAENQ 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1886 LKTVEELNK-----SKELLNEENQKMEEFKKEIETLKQAAAQKSQQlsaLQEENVKLAEELGRTRDEVTSHQKLEEERSV 1960
Cdd:pfam05262  280 KREIEKAQIeikknDEEALKAKDHKAFDLKQESKASEKEAEDKELE---AQKKREPVAEDLQKTKPQVEAQPTSLNEDAI 356
PRK11281 PRK11281
mechanosensitive channel MscK;
1679-1931 2.91e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.98  E-value: 2.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1679 QEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSK---SKLELQELHSCLTKILDDLR--------LNHEVA 1747
Cdd:PRK11281   73 DKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRetlSTLSLRQLESRLAQTLDQLQnaqndlaeYNSQLV 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1748 ----VTERAEV--------LQDNKNLLAEKREMMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSEnr 1815
Cdd:PRK11281  153 slqtQPERAQAalyansqrLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQRKSLEGNTQLQDLLQKQRD-- 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1816 tlrkdksKLTLKIRELEtlHSFTAAQTAEDAMQImeQMTKEKTETLASLEDT--KQTNAKLQSELDTlkenNLKTVEELN 1893
Cdd:PRK11281  231 -------YLTARIQRLE--HQLQLLQEAINSKRL--TLSEKTVQEAQSQDEAarIQANPLVAQELEI----NLQLSQRLL 295

                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 672073054 1894 KSKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQ 1931
Cdd:PRK11281  296 KATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVLK 333
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1685-1984 3.16e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 3.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1685 EQKVVEIIKEKELLSAEtaqlaaNIETLKSDFAALSKSKLELQELHScLTKILDDLRLNHEVAVTEraEVLQDnknllae 1764
Cdd:PRK05771   27 ELGVVHIEDLKEELSNE------RLRKLRSLLTKLSEALDKLRSYLP-KLNPLREEKKKVSVKSLE--ELIKD------- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1765 kremmlrneeVLKEKEKLEESYFVLQKEISQLaqtnshisadlleaqsENRtlrkdKSKLTLKIRELETLHSFTA----A 1840
Cdd:PRK05771   91 ----------VEEELEKIEKEIKELEEEISEL----------------ENE-----IKELEQEIERLEPWGNFDLdlslL 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1841 QTAEDAMQIMEQMTKEKTETLASLEDtkQTNAKlqsELDTLKENNLKTVEELNKSKELLNEENQKMEEFKKEI---ETLK 1917
Cdd:PRK05771  140 LGFKYVSVFVGTVPEDKLEELKLESD--VENVE---YISTDKGYVYVVVVVLKELSDEVEEELKKLGFERLELeeeGTPS 214

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672073054 1918 QAAAQKSQQLSALQEENVKLAEELGRtrdevtSHQKLEEERSVLNNQLLEMKKRESEYRKDADEEKA 1984
Cdd:PRK05771  215 ELIREIKEELEEIEKERESLLEELKE------LAKKYLEELLALYEYLEIELERAEALSKFLKTDKT 275
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1738-1976 3.60e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 3.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1738 DDLRLNHEVAVTERAEVlqdnkNLLAEKREMMLRNEEVLKEKEKLEE-----SYFVLQKEISQLAQTNSHISADLLEAQS 1812
Cdd:COG4913   235 DDLERAHEALEDAREQI-----ELLEPIRELAERYAAARERLAELEYlraalRLWFAQRRLELLEAELEELRAELARLEA 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1813 ENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQSELDT----LKENNLKT 1888
Cdd:COG4913   310 ELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPAsaeeFAALRAEA 389

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1889 VEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEM 1968
Cdd:COG4913   390 AALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELPFVGELIEV 469


                  ....*...
gi 672073054 1969 KKRESEYR 1976
Cdd:COG4913   470 RPEEERWR 477
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1656-1873 3.63e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 3.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1656 LEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQELHSCLTK 1735
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLR 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1736 ILDDLRLNHEVAVTERAEVLQDnknllAEKREMMLR--NEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSE 1813
Cdd:COG4942   112 ALYRLGRQPPLALLLSPEDFLD-----AVRRLQYLKylAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEE 186

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1814 NRTLRKDKSKLTLKIRELEtlhsfTAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAK 1873
Cdd:COG4942   187 RAALEALKAERQKLLARLE-----KELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 842-1085 4.40e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  842 NQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKA 921
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  922 KEKLENDIAEIM----KMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASLLQKSIGEVTLKAEQSQQEAAKKHE 997
Cdd:COG4942    99 LEAQKEELAELLralyRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  998 EEKKElenkllelekkmetshyqcQDLKAKYEKASSEtkikHEEILQNFQKMLVDTEDKLKAAQEANRDLMQDMEELKSQ 1077
Cdd:COG4942   179 LLAEL-------------------EEERAALEALKAE----RQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235


                  ....*...
gi 672073054 1078 ADKAKSLT 1085
Cdd:COG4942   236 AAAAAERT 243
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 347-614 4.43e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  347 SGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELAlardghdqhvlELEAKMDQLRTMVEAADREKVEL 426
Cdd:COG4942    13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLA-----------ALERRIAALARRIRALEQELAAL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  427 LNQLEEEKRKVEDLQFRVEeesitkgdlEQKSQISEDPENTQTKLEHARIKeleqsLLFEKTKADKLQRELEDTRVATVS 506
Cdd:COG4942    82 EAELAELEKEIAELRAELE---------AQKEELAELLRALYRLGRQPPLA-----LLLSPEDFLDAVRRLQYLKYLAPA 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  507 EKSRIMELEKDLalrvQEVAELRRRLESSKppgdvDMSLSLLQEISALQEKLEVTHTDHQNEVTSLkdhfgtreemfQKE 586
Cdd:COG4942   148 RREQAEELRADL----AELAALRAELEAER-----AELEALLAELEEERAALEALKAERQKLLARL-----------EKE 207

                         250       260
                  ....*....|....*....|....*...
gi 672073054  587 IKALHAATEKLSKENESLRSKLDHANKE 614
Cdd:COG4942   208 LAELAAELAELQQEAEELEALIARLEAE 235
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 786-955 4.46e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.38  E-value: 4.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  786 KLEIETLRQQLEGAEKQIKNLEMERNAESSKansitKDLQGKELmltslqsnlnevnqvKETLEKELQTLKEKFASASEE 865
Cdd:COG0542   403 RMEIDSKPEELDELERRLEQLEIEKEALKKE-----QDEASFER---------------LAELRDELAELEEELEALKAR 462

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  866 avstQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKakeklENDIAEIM---------KMS 936
Cdd:COG0542   463 ----WEAEKELIEEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLREEVT-----EEDIAEVVsrwtgipvgKLL 533

                         170
                  ....*....|....*....
gi 672073054  937 GDNSSQLTKMNDElrLKER 955
Cdd:COG0542   534 EGEREKLLNLEEE--LHER 550
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
829-1175 5.11e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 5.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  829 LMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKF 908
Cdd:COG4372    24 ILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEEL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  909 KEKDEREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASLLQKSIGEVTLKAEQS 988
Cdd:COG4372   104 ESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQ 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  989 QQEAAKKHEEEKKELENKLLELEKKMETSHYQCQDLKAKYEKASSETKIKHEEILQNFQKMLVDTEDKLKAAQEANRDLM 1068
Cdd:COG4372   184 ALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEEL 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054 1069 QDMEELKSQADKAKSLTYLLTSAKKEIEVMSEELRGLKSEKQLFAQEASALKLEKGSLLSKLIEVETKITLLQEDQQKLW 1148
Cdd:COG4372   264 ELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLL 343

                         330       340
                  ....*....|....*....|....*..
gi 672073054 1149 SVNENLHLEKERISEEKQVAEKRYQQE 1175
Cdd:COG4372   344 QLLLVGLLDNDVLELLSKGAEAGVADG 370
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
479-1070 5.77e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 5.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  479 LEQSLLFEKtkADKLQ---RELEDTRVATVSEKSRIMELE--KDLALRVQEVAELRRRLESSKPPGDVDMSLSLLQEISA 553
Cdd:COG4913   218 LEEPDTFEA--ADALVehfDDLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  554 LQEKLEVTHTDHQNEVTSLKDHFGTREEmfqkEIKALHAATEKLSKEN-ESLRSKLDHANKEnsdvialwKSKLETAIAS 632
Cdd:COG4913   296 ELEELRAELARLEAELERLEARLDALRE----ELDELEAQIRGNGGDRlEQLEREIERLERE--------LEERERRRAR 363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  633 HQQAMEELKVSFSkgigTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAhakemesmKAKLMKIIKEKEDSLEAV 712
Cdd:COG4913   364 LEALLAALGLPLP----ASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA--------LRDLRRELRELEAEIASL 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  713 KARlDTAEDQHLVEMEEMLSklQEAEIKVKEL----EVLQAKYSE---QTQVVGHLTSQ-LS-VVEEQLLDlDALRKANS 783
Cdd:COG4913   432 ERR-KSNIPARLLALRDALA--EALGLDEAELpfvgELIEVRPEEerwRGAIERVLGGFaLTlLVPPEHYA-AALRWVNR 507

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  784 EgKLEietLRQQLEGAEKQIKNLEMERnaesSKANSITKDLQGKElmltslqsnlnevNQVKETLEKELQtlkEKFASA- 862
Cdd:COG4913   508 L-HLR---GRLVYERVRTGLPDPERPR----LDPDSLAGKLDFKP-------------HPFRAWLEAELG---RRFDYVc 563

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  863 --SEEAVS------TQTSM-----------------------QDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAKFKEK 911
Cdd:COG4913   564 vdSPEELRrhpraiTRAGQvkgngtrhekddrrrirsryvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDAL 643

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  912 DEREDQLVKAKEKL--ENDIAEIMKMSGDNSSQLTKM---NDELRLKERSVEELQLKLTKANENASLLQKSIGEVTLKAE 986
Cdd:COG4913   644 QERREALQRLAEYSwdEIDVASAEREIAELEAELERLdasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELE 723

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  987 QSQQEAAKKHEEEKKELENKLLELEkkmetshyqcQDLKAKYEKASSETkiKHEEILQNFQKMLVDTEDKLKAAQEANRD 1066
Cdd:COG4913   724 QAEEELDELQDRLEAAEDLARLELR----------ALLEERFAAALGDA--VERELRENLEERIDALRARLNRAEEELER 791


                  ....
gi 672073054 1067 LMQD 1070
Cdd:COG4913   792 AMRA 795
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1611-1938 5.96e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 41.88  E-value: 5.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1611 QEECQKLNEEIREIQQTLMLEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVVE 1690
Cdd:pfam02463  182 TENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIE 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1691 IIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQE---LHSCLTKILDDLRLNHEVAVTERAEVLQDNKNLLAEKRE 1767
Cdd:pfam02463  262 KEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKselLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1768 MMLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLHSFTAAQTAEDAM 1847
Cdd:pfam02463  342 KELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1848 QIMEQMTKEKTETLASLEDTKQTNAKLQSELDTL--KENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQKSQ 1925
Cdd:pfam02463  422 KEEKKEELEILEEEEESIELKQGKLTEEKEELEKqeLKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQK 501

                          330
                   ....*....|...
gi 672073054  1926 QLSALQEENVKLA 1938
Cdd:pfam02463  502 ESKARSGLKVLLA 514
PLN02939 PLN02939
transferase, transferring glycosyl groups
 643-991 6.12e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 41.81  E-value: 6.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  643 SFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMESMKAKLMKIIKEKED----SLEAVKARLDT 718
Cdd:PLN02939   60 SSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSKDGEQlsdfQLEDLVGMIQN 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  719 AEDQHLVEMEEMLSKLQEAEIKVKELEVLQAKyseqtqvvghltsqLSVVEEQLLDLDALRKANSEGKLEIETLRQQLEg 798
Cdd:PLN02939  140 AEKNILLLNQARLQALEDLEKILTEKEALQGK--------------INILEMRLSETDARIKLAAQEKIHVEILEEQLE- 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  799 aekqikNLEMERNAESSKANSITKDLqGKELMLTSLQSNLnevnqvketLEKELQTLKEKFASASEeavstqtsmqdtvn 878
Cdd:PLN02939  205 ------KLRNELLIRGATEGLCVHSL-SKELDVLKEENML---------LKDDIQFLKAELIEVAE-------------- 254

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  879 klhqKEEQFNMLSSELEKLRENLTDMEAKFKEKDEREDQLVKAK-----EKLEN--DIAEIMKMSGDNSSQLTKMNDELR 951
Cdd:PLN02939  255 ----TEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQydcwwEKVENlqDLLDRATNQVEKAALVLDQNQDLR 330

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 672073054  952 LKersVEELQLKLTKAN------ENASLLQKSIGEVTLKAEQSQQE 991
Cdd:PLN02939  331 DK---VDKLEASLKEANvskfssYKVELLQQKLKLLEERLQASDHE 373
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1150-1482 7.05e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.65  E-value: 7.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1150 VNENLHLekerISEEKQVAEkRYQQEHRDKeslvVEREKLLKEinvtQEELLKMHMEKDSLEASKVSMQVLIEELR--FC 1227
Cdd:pfam17380  271 LNQLLHI----VQHQKAVSE-RQQQEKFEK----MEQERLRQE----KEEKAREVERRRKLEEAEKARQAEMDRQAaiYA 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1228 KDKLMAMSEKARAEKEQLEGQVKKLTAENMVLVKDKDDVIQKLQSAYEELVKDQKALVQEIEDLTTEKKSAAEKQMNLDN 1307
Cdd:pfam17380  338 EQERMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQ 417

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1308 TCLTL---KAERENLLQsnRDLQ-FEKDTLRQGQEKLSASLEATLQVKQLLSTEAETLRTQLDCATKALRKAELDmrqlQ 1383
Cdd:pfam17380  418 QKVEMeqiRAEQEEARQ--REVRrLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAE----E 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1384 TSNTSLTKLLEEIKtcRAITDSECIQLLHEKE------SLAASERALLAE----KEELLNENRVITEKLNKHSEEVTRLE 1453
Cdd:pfam17380  492 QRRKILEKELEERK--QAMIEEERKRKLLEKEmeerqkAIYEEERRREAEeerrKQQEMEERRRIQEQMRKATEERSRLE 569

                          330       340
                   ....*....|....*....|....*....
gi 672073054  1454 VslnekityLTSEKEMACQKVARLKKQQD 1482
Cdd:pfam17380  570 A--------MEREREMMRQIVESEKARAE 590
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1609-1946 7.17e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.42  E-value: 7.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1609 NLQEECQKlneEIREIQQTLMLEKEARAKESESSLYESNKLHGRIVLLEEEIQGLRTCSEQLQTENFTLTQEKTNSEQKV 1688
Cdd:pfam07888   34 NRLEECLQ---ERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASS 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1689 VEIIKEKELLSAETAQLAANIETLKSDFAALSKSKLELQelhscltkilddlrlnhevavTERAEVLQDNKNLLAEKREM 1768
Cdd:pfam07888  111 EELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERE---------------------TELERMKERAKKAGAQRKEE 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1769 MLRNEEVLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSENRTLRKDKSKLTLKIRELETLHS-FTAAQTAEDAM 1847
Cdd:pfam07888  170 EAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEeLRSLQERLNAS 249

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1848 QIMEQMTKEKTETLASLEDTKQTN---AKLQSELDTLK--ENNLKTVEELNKSKELLNEENQKMEEFKKEIETLKQAAAQ 1922
Cdd:pfam07888  250 ERKVEGLGEELSSMAAQRDRTQAElhqARLQAAQLTLQlaDASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQR 329

                          330       340
                   ....*....|....*....|....
gi 672073054  1923 KSQQLSALQEENVKLAEELGRTRD 1946
Cdd:pfam07888  330 LEERLQEERMEREKLEVELGREKD 353
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 670-866 7.51e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 7.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  670 QHEIESLQSKQDSERSAhAKEMESMKAKLMKIIKEKEDSLEAVKARLDTAEDQhLVEMEEMLSKLQEAEIKV-KELEVLQ 748
Cdd:COG4942    26 EAELEQLQQEIAELEKE-LAALKKEEKALLKQLAALERRIAALARRIRALEQE-LAALEAELAELEKEIAELrAELEAQK 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  749 AKYSEQ----------------------TQVVGHLTSQLSVVEEQLLDLDALRKAnsegKLEIETLRQQLEGAEKQIKNL 806
Cdd:COG4942   104 EELAELlralyrlgrqpplalllspedfLDAVRRLQYLKYLAPARREQAEELRAD----LAELAALRAELEAERAELEAL 179

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  807 EMERNAEsskANSITKDLQGKELMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEA 866
Cdd:COG4942   180 LAELEEE---RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 353-951 7.75e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.49  E-value: 7.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   353 QEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGH--DQHVLELEAKMDQLRTMVEAADREKVELLNQL 430
Cdd:TIGR00618  337 QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHtlQQQKTTLTQKLQSLCKELDILQREQATIDTRT 416

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   431 EEEKRKVEDLQFRVEEESITKGDLEQKSQISEDpENTQTKLEHARIKELEQSLLFEKTK-ADKLQRELEDTRVATVSEKS 509
Cdd:TIGR00618  417 SAFRDLQGQLAHAKKQQELQQRYAELCAAAITC-TAQCEKLEKIHLQESAQSLKEREQQlQTKEQIHLQETRKKAVVLAR 495

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   510 RIMELEKDLALRVQEVAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEvtHTDHQneVTSLKDHFGTREEMFQKEIKA 589
Cdd:TIGR00618  496 LLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE--DVYHQ--LTSERKQRASLKEQMQEIQQS 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   590 LHAATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQameelkvsfskgigtdsaefaELKTQIErlrLDY 669
Cdd:TIGR00618  572 FSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHAL---------------------LRKLQPE---QDL 627

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   670 QHEIESLQSKQDSErsahAKEMESMKAKLMKIIKEKE-DSLEAVKARLDTAEDQHLVEMEEMLSKLQEAEIKVKELEVLQ 748
Cdd:TIGR00618  628 QDVRLHLQQCSQEL----ALKLTALHALQLTLTQERVrEHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQ 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   749 AKYSEQTQVVGHLTSQlsvVEEQLLdldALRKANSEGKLEIETLRQQLEGAEKQIKN-LEMERNAESSKANSITKDLQgk 827
Cdd:TIGR00618  704 TLLRELETHIEEYDRE---FNEIEN---ASSSLGSDLAAREDALNQSLKELMHQARTvLKARTEAHFNNNEEVTAALQ-- 775

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054   828 elMLTSLQSNLNEVNQVKETLEKELQTLKEKFASASEEAVSTQTSMQDTVNKLHQKEEQFNMLSSELEKLRENLTDMEAK 907
Cdd:TIGR00618  776 --TGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLK 853

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 672073054   908 FKEKDEREDQLVKAKEKLendIAEIMKMSGDNSSQLTKMNDELR 951
Cdd:TIGR00618  854 YEECSKQLAQLTQEQAKI---IQLSDKLNGINQIKIQFDGDALI 894
CCDC73 pfam15818
Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil ...
 1657-1974 9.10e-03

Coiled-coil domain-containing protein 73 family; CCDC73 is a family of eukaryotic coiled-coil containing proteins. The function is not known. The alternative name is sarcoma antigen NY-SAR-79.


Pssm-ID: 464893 [Multi-domain]  Cd Length: 1048  Bit Score: 41.47  E-value: 9.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1657 EEEIQGLRTCSEQLQTENFTLTQEKTNSEQKVveiikEKELLSAETAQLAANietlksdfaalsksklELQELHSCLTKI 1736
Cdd:pfam15818   91 EKEIEGLKETLKALQVSKYSLQKKVSEMEQKL-----QLHLLAKEDHHKQLN----------------EIEKYYATITGQ 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1737 LDDLRLNHEVAVTERAEVLQDNKNL--LAEKREMMLRNeevLKEKEKLEESYFVLQKEISQLAQTNSHISADLLEAQSEN 1814
Cdd:pfam15818  150 FGLVKENHGKLEQNVQEAIQLNKRLsaLNKKQESEICS---LKKELKKVTSDLIKSKVTCQYKMGEENINLTIKEQKFQE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1815 RTLRKD-KSKLTLKIRElETLHSFTAAQTAEDAMQIMEQMTKEKTetlasledtkQTNAKLQSELDTLKENN--LKTVEE 1891
Cdd:pfam15818  227 LQERLNmELELNKKINE-EITHIQEEKQDIIISFQHMQQLLQQQT----------QANTEMEAELKALKENNqtLERDNE 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672073054  1892 LNKSK---------ELLNEENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEElgrtRDEVTSHQKLEEERSV-- 1960
Cdd:pfam15818  296 LQREKvkeneekflNLQNEHEKALGTWKKHVEELNGEINEIKNELSSLKETHIKLQEH----YNKLCNQKKFEEDKKFqn 371

                          330
                   ....*....|....*..
gi 672073054  1961 ---LNNQLLEMKKRESE 1974
Cdd:pfam15818  372 vpeVNNENSEMSTEKSE 388
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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