NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|672069799|ref|XP_008766595|]
View 

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B isoform X1 [Rattus norvegicus]

Protein Classification

glycosyltransferase family 18 protein( domain architecture ID 10633245)

glycosyltransferase family 18 protein may act as alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase that contributes to the creation of branches in complex-type N-glycans

CAZY:  GT18
EC:  2.4.1.-
Gene Ontology:  GO:0030144|GO:0006487

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Glyco_transf_18 pfam15024
Glycosyltransferase family 18; Enzymes belonging to glycosyltransferase family 18 (alpha-1, ...
184-775 0e+00

Glycosyltransferase family 18; Enzymes belonging to glycosyltransferase family 18 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase) contribute to the creation of branches in complex-type N-glycans. This domain is responsible for the catalytic activity of the enzyme.


:

Pssm-ID: 434401  Cd Length: 557  Bit Score: 1058.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  184 CYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTATRTAHKslpRVQAMFRSNLSHLLELMGSGKEsLIFMKKRTRRFTA 263
Cdd:pfam15024   1 CYAFYGVDGSECSFLIYLSEVENWCPPLPWRNKTTAPTRKK---PGQAVIRTSLTRLLEIIGSSEE-FKWMKQRIRRMWE 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  264 QWTKAAKYLAQKLGDIRRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILAALYMLGHSLRVTVSLKELQSN 343
Cdd:pfam15024  77 QWLEAARSLAEKYNLTMRKQKKILVHLGFLANESGFKIAEKAFKGGPLGELVQWSDLIAALYILGHHLKVSTSLEELRSL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  344 LGVPPGRGNCPLTVPLPFDLIYTDYHGLQQMKQYMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNP 423
Cdd:pfam15024 157 LGVPPGRGSCPITGPLPFDLIYTDIHGLAQLKQVMGLSFKHYRCRIRVLDSFGTEPEFNHASYATKHGYRTPWGGWNLNP 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  424 KQFMTMFPHTPDNSFMGFVSEE-LNETEKQLIKDGKASNMAVVYGKEASIWKGKEKFLAILNKYMEIHGTVYYESQRPPE 502
Cdd:pfam15024 237 KQFMTMFPHTPDNSFLGFVVEEhLNETDTELIDSIKKQNQALVYGKEDYMWKGKEKYLDVIHKYMEIHGTVYYEGGRPSH 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  503 VPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPY 582
Cdd:pfam15024 317 VPSFVKNHGILPGRELQQLLREAKVFVGLGFPYEGPAPLEAIANGCVFLNPRFKPPHSSLNTEFFKGKPTLREVTSQHPY 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  583 AENFIGKPHVWTVDYNNSDEFEATIKAIMNTQVDPYLPYEYTCVGMLERINAYIQHQDFCGGPSPVplgsntaqslfvla 662
Cdd:pfam15024 397 AEEFIGKPHVWTVDINNSTEVEEAIKAILNTKVKPYLPYEFTCEGMLERVNALIEKQDFCSDSSPR-------------- 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  663 pnathlewaqnissvpgaWPPPHSLRAWLAAPGRACTDACLDHGLVCEPSFFPFLNSQDAFLRLQVPCDSTEWEMHHLYP 742
Cdd:pfam15024 463 ------------------WPPLSALRVLLGEAGQSCKQACQSKGLICEPAFFPHINKPKAFARLGISCSSTESEMDHLFP 524
                         570       580       590
                  ....*....|....*....|....*....|...
gi 672069799  743 AFAQPGQECYLQKEPLLFSCAGASTKYQRLCPC 775
Cdd:pfam15024 525 AYSPKGRHCYLQSDPLLFSCAGSSPSYRRLCPC 557
 
Name Accession Description Interval E-value
Glyco_transf_18 pfam15024
Glycosyltransferase family 18; Enzymes belonging to glycosyltransferase family 18 (alpha-1, ...
184-775 0e+00

Glycosyltransferase family 18; Enzymes belonging to glycosyltransferase family 18 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase) contribute to the creation of branches in complex-type N-glycans. This domain is responsible for the catalytic activity of the enzyme.


Pssm-ID: 434401  Cd Length: 557  Bit Score: 1058.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  184 CYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTATRTAHKslpRVQAMFRSNLSHLLELMGSGKEsLIFMKKRTRRFTA 263
Cdd:pfam15024   1 CYAFYGVDGSECSFLIYLSEVENWCPPLPWRNKTTAPTRKK---PGQAVIRTSLTRLLEIIGSSEE-FKWMKQRIRRMWE 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  264 QWTKAAKYLAQKLGDIRRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILAALYMLGHSLRVTVSLKELQSN 343
Cdd:pfam15024  77 QWLEAARSLAEKYNLTMRKQKKILVHLGFLANESGFKIAEKAFKGGPLGELVQWSDLIAALYILGHHLKVSTSLEELRSL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  344 LGVPPGRGNCPLTVPLPFDLIYTDYHGLQQMKQYMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNP 423
Cdd:pfam15024 157 LGVPPGRGSCPITGPLPFDLIYTDIHGLAQLKQVMGLSFKHYRCRIRVLDSFGTEPEFNHASYATKHGYRTPWGGWNLNP 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  424 KQFMTMFPHTPDNSFMGFVSEE-LNETEKQLIKDGKASNMAVVYGKEASIWKGKEKFLAILNKYMEIHGTVYYESQRPPE 502
Cdd:pfam15024 237 KQFMTMFPHTPDNSFLGFVVEEhLNETDTELIDSIKKQNQALVYGKEDYMWKGKEKYLDVIHKYMEIHGTVYYEGGRPSH 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  503 VPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPY 582
Cdd:pfam15024 317 VPSFVKNHGILPGRELQQLLREAKVFVGLGFPYEGPAPLEAIANGCVFLNPRFKPPHSSLNTEFFKGKPTLREVTSQHPY 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  583 AENFIGKPHVWTVDYNNSDEFEATIKAIMNTQVDPYLPYEYTCVGMLERINAYIQHQDFCGGPSPVplgsntaqslfvla 662
Cdd:pfam15024 397 AEEFIGKPHVWTVDINNSTEVEEAIKAILNTKVKPYLPYEFTCEGMLERVNALIEKQDFCSDSSPR-------------- 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  663 pnathlewaqnissvpgaWPPPHSLRAWLAAPGRACTDACLDHGLVCEPSFFPFLNSQDAFLRLQVPCDSTEWEMHHLYP 742
Cdd:pfam15024 463 ------------------WPPLSALRVLLGEAGQSCKQACQSKGLICEPAFFPHINKPKAFARLGISCSSTESEMDHLFP 524
                         570       580       590
                  ....*....|....*....|....*....|...
gi 672069799  743 AFAQPGQECYLQKEPLLFSCAGASTKYQRLCPC 775
Cdd:pfam15024 525 AYSPKGRHCYLQSDPLLFSCAGSSPSYRRLCPC 557
 
Name Accession Description Interval E-value
Glyco_transf_18 pfam15024
Glycosyltransferase family 18; Enzymes belonging to glycosyltransferase family 18 (alpha-1, ...
184-775 0e+00

Glycosyltransferase family 18; Enzymes belonging to glycosyltransferase family 18 (alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase) contribute to the creation of branches in complex-type N-glycans. This domain is responsible for the catalytic activity of the enzyme.


Pssm-ID: 434401  Cd Length: 557  Bit Score: 1058.42  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  184 CYAFFGVDGTECSFLIYLSEVEWFCPPLPWRNQTATRTAHKslpRVQAMFRSNLSHLLELMGSGKEsLIFMKKRTRRFTA 263
Cdd:pfam15024   1 CYAFYGVDGSECSFLIYLSEVENWCPPLPWRNKTTAPTRKK---PGQAVIRTSLTRLLEIIGSSEE-FKWMKQRIRRMWE 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  264 QWTKAAKYLAQKLGDIRRDQKQILVHIGFLTEESGDVFSPRVLKGGPLGEMVQWADILAALYMLGHSLRVTVSLKELQSN 343
Cdd:pfam15024  77 QWLEAARSLAEKYNLTMRKQKKILVHLGFLANESGFKIAEKAFKGGPLGELVQWSDLIAALYILGHHLKVSTSLEELRSL 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  344 LGVPPGRGNCPLTVPLPFDLIYTDYHGLQQMKQYMGLSFKKYRCRIRVIDTFGTEPAYNHEEYATLHGYRTNWGYWNLNP 423
Cdd:pfam15024 157 LGVPPGRGSCPITGPLPFDLIYTDIHGLAQLKQVMGLSFKHYRCRIRVLDSFGTEPEFNHASYATKHGYRTPWGGWNLNP 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  424 KQFMTMFPHTPDNSFMGFVSEE-LNETEKQLIKDGKASNMAVVYGKEASIWKGKEKFLAILNKYMEIHGTVYYESQRPPE 502
Cdd:pfam15024 237 KQFMTMFPHTPDNSFLGFVVEEhLNETDTELIDSIKKQNQALVYGKEDYMWKGKEKYLDVIHKYMEIHGTVYYEGGRPSH 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  503 VPAFVKNHGLLPQPEFQQLLRKAKLFIGFGFPYEGPAPLEAIANGCIFLQSRFSPPHSSLNHEFFRGKPTSREVFSQHPY 582
Cdd:pfam15024 317 VPSFVKNHGILPGRELQQLLREAKVFVGLGFPYEGPAPLEAIANGCVFLNPRFKPPHSSLNTEFFKGKPTLREVTSQHPY 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  583 AENFIGKPHVWTVDYNNSDEFEATIKAIMNTQVDPYLPYEYTCVGMLERINAYIQHQDFCGGPSPVplgsntaqslfvla 662
Cdd:pfam15024 397 AEEFIGKPHVWTVDINNSTEVEEAIKAILNTKVKPYLPYEFTCEGMLERVNALIEKQDFCSDSSPR-------------- 462
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069799  663 pnathlewaqnissvpgaWPPPHSLRAWLAAPGRACTDACLDHGLVCEPSFFPFLNSQDAFLRLQVPCDSTEWEMHHLYP 742
Cdd:pfam15024 463 ------------------WPPLSALRVLLGEAGQSCKQACQSKGLICEPAFFPHINKPKAFARLGISCSSTESEMDHLFP 524
                         570       580       590
                  ....*....|....*....|....*....|...
gi 672069799  743 AFAQPGQECYLQKEPLLFSCAGASTKYQRLCPC 775
Cdd:pfam15024 525 AYSPKGRHCYLQSDPLLFSCAGSSPSYRRLCPC 557
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH