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Conserved domains on  [gi|672069501|ref|XP_008766504|]
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microtubule-associated protein tau isoform X1 [Rattus norvegicus]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 604-633 9.34e-15

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 68.21  E-value: 9.34e-15
                          10        20        30
                  ....*....|....*....|....*....|
gi 672069501  604 VQIINKKLDLSNVQSKCGSKDNIKHVPGGG 633
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 635-664 6.72e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 57.42  E-value: 6.72e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 672069501  635 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 664
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 666-696 4.26e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 55.11  E-value: 4.26e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 672069501  666 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 696
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 221-591 8.17e-10

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 62.65  E-value: 8.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  221 SPPSQASLAPGTATPQARSVSASGVSGETTSIP----GFPAEGSIPLPADFFSKVSAETQASPPEGP------------- 283
Cdd:PHA03247 2617 LPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPerprDDPAPGRVSRPRRARRLGRAAQASSPPQRPrrraarptvgslt 2696

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  284 ---GTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGRPV 360
Cdd:PHA03247 2697 slaDPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPA 2776

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  361 SRVPQLKARVAGVSKDRTGNdekkAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPR 440
Cdd:PHA03247 2777 AGPPRRLTRPAVASLSESRE----SLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  441 NGS--PGtKQMKLKGADGKTGAKIATPRG--AATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGAKTERGE 516
Cdd:PHA03247 2853 GGSvaPG-GDVRRRPPSRSPAAKPAAPARppVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672069501  517 PPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTRE--PKKVAVVRTppKSPSASKSRLQTAPVPMPDLKNVRSKIGS 591
Cdd:PHA03247 2932 PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAlvPGRVAVPRF--RVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
PRK10263 super family cl35903
DNA translocase FtsK; Provisional
 34-264 5.12e-03

DNA translocase FtsK; Provisional


The actual alignment was detected with superfamily member PRK10263:

Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.45  E-value: 5.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501   34 ESPPQPPADDGSEEPGSETSDAKSTPTAEDVTAPLVEERAPDKQ-----ATAQSHTEIP-EGTTAEEAGIGDTPNMEDQA 107
Cdd:PRK10263  342 QTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQyaqpaVQYNEPLQQPvQPQQPYYAPAAEQPAQQPYY 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  108 AGHVTQEPQKVEIFSQSllVEPGRREGQAPDSGISDWTHQ------QVPSMSGAPLPPQGLREATHQPLGTRPED-VERS 180
Cdd:PRK10263  422 APAPEQPAQQPYYAPAP--EQPVAGNAWQAEEQQSTFAPQstyqteQTYQQPAAQEPLYQQPQPVEQQPVVEPEPvVEET 499

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  181 HPASELLW--QESPQKEAWGKDRLGS-----EEEVDEDITMDESSqeSPPSQASLAPGTATPQARSVSAS-------GVS 246
Cdd:PRK10263  500 KPARPPLYyfEEVEEKRAREREQLAAwyqpiPEPVKEPEPIKSSL--KAPSVAAVPPVEAAAAVSPLASGvkkatlaTGA 577

                         250
                  ....*....|....*....
gi 672069501  247 GETTSIPGF-PAEGSIPLP 264
Cdd:PRK10263  578 AATVAAPVFsLANSGGPRP 596
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 604-633 9.34e-15

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 68.21  E-value: 9.34e-15
                          10        20        30
                  ....*....|....*....|....*....|
gi 672069501  604 VQIINKKLDLSNVQSKCGSKDNIKHVPGGG 633
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 635-664 6.72e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 57.42  E-value: 6.72e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 672069501  635 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 664
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 666-696 4.26e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 55.11  E-value: 4.26e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 672069501  666 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 696
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 221-591 8.17e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 62.65  E-value: 8.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  221 SPPSQASLAPGTATPQARSVSASGVSGETTSIP----GFPAEGSIPLPADFFSKVSAETQASPPEGP------------- 283
Cdd:PHA03247 2617 LPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPerprDDPAPGRVSRPRRARRLGRAAQASSPPQRPrrraarptvgslt 2696

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  284 ---GTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGRPV 360
Cdd:PHA03247 2697 slaDPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPA 2776

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  361 SRVPQLKARVAGVSKDRTGNdekkAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPR 440
Cdd:PHA03247 2777 AGPPRRLTRPAVASLSESRE----SLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  441 NGS--PGtKQMKLKGADGKTGAKIATPRG--AATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGAKTERGE 516
Cdd:PHA03247 2853 GGSvaPG-GDVRRRPPSRSPAAKPAAPARppVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672069501  517 PPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTRE--PKKVAVVRTppKSPSASKSRLQTAPVPMPDLKNVRSKIGS 591
Cdd:PHA03247 2932 PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAlvPGRVAVPRF--RVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 346-580 1.49e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.87  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  346 PTDKQPAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTP-----SNRPCLSPTRPTPGSSDPLIKPSS 420
Cdd:pfam17823 145 PRAAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPttaasSAPATLTPARGISTAATATGHPAA 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  421 pavcpepATSPKYVSSVTPrngSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQ 500
Cdd:pfam17823 225 -------GTALAAVGNSSP---AAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARN 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  501 PqrkLPPAGAKTERGEPPKSGERSGYSSPGSPgTPGSRSRTPSLPTPPTREPKKVAVVRTP---PKSPSASksrlqtaPV 577
Cdd:pfam17823 295 P---AAPMGAQAQGPIIQVSTDQPVHNTAGEP-TPSPSNTTLEPNTPKSVASTNLAVVTTTkaqAKEPSAS-------PV 363


                  ...
gi 672069501  578 PMP 580
Cdd:pfam17823 364 PVL 366
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 34-264 5.12e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.45  E-value: 5.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501   34 ESPPQPPADDGSEEPGSETSDAKSTPTAEDVTAPLVEERAPDKQ-----ATAQSHTEIP-EGTTAEEAGIGDTPNMEDQA 107
Cdd:PRK10263  342 QTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQyaqpaVQYNEPLQQPvQPQQPYYAPAAEQPAQQPYY 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  108 AGHVTQEPQKVEIFSQSllVEPGRREGQAPDSGISDWTHQ------QVPSMSGAPLPPQGLREATHQPLGTRPED-VERS 180
Cdd:PRK10263  422 APAPEQPAQQPYYAPAP--EQPVAGNAWQAEEQQSTFAPQstyqteQTYQQPAAQEPLYQQPQPVEQQPVVEPEPvVEET 499

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  181 HPASELLW--QESPQKEAWGKDRLGS-----EEEVDEDITMDESSqeSPPSQASLAPGTATPQARSVSAS-------GVS 246
Cdd:PRK10263  500 KPARPPLYyfEEVEEKRAREREQLAAwyqpiPEPVKEPEPIKSSL--KAPSVAAVPPVEAAAAVSPLASGvkkatlaTGA 577

                         250
                  ....*....|....*....
gi 672069501  247 GETTSIPGF-PAEGSIPLP 264
Cdd:PRK10263  578 AATVAAPVFsLANSGGPRP 596
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 604-633 9.34e-15

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 68.21  E-value: 9.34e-15
                          10        20        30
                  ....*....|....*....|....*....|
gi 672069501  604 VQIINKKLDLSNVQSKCGSKDNIKHVPGGG 633
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 635-664 6.72e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 57.42  E-value: 6.72e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 672069501  635 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 664
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 666-696 4.26e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 55.11  E-value: 4.26e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 672069501  666 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 696
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 221-591 8.17e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 62.65  E-value: 8.17e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  221 SPPSQASLAPGTATPQARSVSASGVSGETTSIP----GFPAEGSIPLPADFFSKVSAETQASPPEGP------------- 283
Cdd:PHA03247 2617 LPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPerprDDPAPGRVSRPRRARRLGRAAQASSPPQRPrrraarptvgslt 2696

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  284 ---GTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGRPV 360
Cdd:PHA03247 2697 slaDPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPA 2776

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  361 SRVPQLKARVAGVSKDRTGNdekkAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPR 440
Cdd:PHA03247 2777 AGPPRRLTRPAVASLSESRE----SLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPL 2852

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  441 NGS--PGtKQMKLKGADGKTGAKIATPRG--AATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGAKTERGE 516
Cdd:PHA03247 2853 GGSvaPG-GDVRRRPPSRSPAAKPAAPARppVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672069501  517 PPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTRE--PKKVAVVRTppKSPSASKSRLQTAPVPMPDLKNVRSKIGS 591
Cdd:PHA03247 2932 PPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAlvPGRVAVPRF--RVPQPAPSREAPASSTPPLTGHSLSRVSS 3006
PHA03247 PHA03247
large tegument protein UL36; Provisional
 262-583 9.12e-10

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 62.65  E-value: 9.12e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  262 PLPADFFSkvSAETQASPPEGPGTGPSEEGHEAApeftfhvEIKASAPKEQDlEGATVVGAPAEEQKARGPSVGKGTKEA 341
Cdd:PHA03247 2554 PLPPAAPP--AAPDRSVPPPRPAPRPSEPAVTSR-------ARRPDAPPQSA-RPRAPVDDRGDPRGPAPPSPLPPDTHA 2623

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  342 SLLEPTDKQPAAGLPGRP-VSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSS 420
Cdd:PHA03247 2624 PDPPPPSPSPAANEPDPHpPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPP 2703

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  421 PAVCPEPAtsPKYVSSVTPRNGSPGTKQMKLKgADGKTGAKIATPRGAATPGqkGTSNATRIPAKTTPSPKTPPGSASKQ 500
Cdd:PHA03247 2704 PPPTPEPA--PHALVSATPLPPGPAAARQASP-ALPAAPAPPAVPAGPATPG--GPARPARPPTTAGPPAPAPPAAPAAG 2778

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  501 PQRKLPP------AGAKTERGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTREPkkvaVVRTPPKSPSASKSRLQT 574
Cdd:PHA03247 2779 PPRRLTRpavaslSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQP----TAPPPPPGPPPPSLPLGG 2854


                  ....*....
gi 672069501  575 APVPMPDLK 583
Cdd:PHA03247 2855 SVAPGGDVR 2863
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 274-552 5.05e-09

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 60.09  E-value: 5.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 274 ETQASPPEGPGTGPSEEGHEaAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQK-------ARGPSVGKGTKEASLLEP 346
Cdd:PTZ00449 515 EASGLPPKAPGDKEGEEGEH-EDSKESDEPKEGGKPGETKEGEVGKKPGPAKEHKpskiptlSKKPEFPKDPKHPKDPEE 593

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 347 TDKQPAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPscaktPSNRPcLSPTRPtpgSSDPLIKPSSPAVCPE 426
Cdd:PTZ00449 594 PKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPP-----PPQRP-SSPERP---EGPKIIKSPKPPKSPK 664

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 427 PATSPKYVSSV--TPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAK-TTPS-PKTPPGS-ASKQP 501
Cdd:PTZ00449 665 PPFDPKFKEKFydDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRPLPPKLpRDEEfPFEPIGDpDAEQP 744

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 672069501 502 ---QRKLPPAGAKTERGEPPKSGERSG-----------YSSPGSPGTPGSRSRTPS--LPTPPTREP 552
Cdd:PTZ00449 745 ddiEFFTPPEEERTFFHETPADTPLPDilaeefkeediHAETGEPDEAMKRPDSPSehEDKPPGDHP 811
PHA03247 PHA03247
large tegument protein UL36; Provisional
 210-580 9.15e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 59.57  E-value: 9.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  210 EDITMDESSQESPPSQASLAPGTA-----TPQAR---SVSASGVSGETTSIPGFPAEGSIPLPADFFSKVSAETQASPPE 281
Cdd:PHA03247 2541 EELASDDAGDPPPPLPPAAPPAAPdrsvpPPRPAprpSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPD 2620

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  282 GPGTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATV--------VGAPAEEQKARGPSVGKGTKEA--------SLLE 345
Cdd:PHA03247 2621 THAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPgrvsrprrARRLGRAAQASSPPQRPRRRAArptvgsltSLAD 2700

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  346 PTDKQPAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPS--NRPCLSPTRPTPGSSDPlikPSSPAV 423
Cdd:PHA03247 2701 PPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGgpARPARPPTTAGPPAPAP---PAAPAA 2777

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  424 CPEPATSPKYVSSVTP-RNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPP-------- 494
Cdd:PHA03247 2778 GPPRRLTRPAVASLSEsRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSlplggsva 2857

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  495 --GSASKQPQRKLPPAGAKTERGEPPKSGERSGYSSPGS----PGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSAS 568
Cdd:PHA03247 2858 pgGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTEsfalPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPP 2937

                         410
                  ....*....|..
gi 672069501  569 KSRLQTAPVPMP 580
Cdd:PHA03247 2938 RPQPPLAPTTDP 2949
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 581-602 1.87e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 47.41  E-value: 1.87e-07
                          10        20
                  ....*....|....*....|..
gi 672069501  581 DLKNVRSKIGSTENLKHQPGGG 602
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 273-600 1.99e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 51.71  E-value: 1.99e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  273 AETQASPPEGPGTGPS--EEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQ 350
Cdd:PHA03307   61 ACDRFEPPTGPPPGPGteAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRP 140

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  351 PAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPSN-------RPCLSPTRPTPGSSDPLIKPSSPAV 423
Cdd:PHA03307  141 VGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSppaepppSTPPAAASPRPPRRSSPISASASSP 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  424 CPEPATSPKYVSSVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQR 503
Cdd:PHA03307  221 APAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSP 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  504 KLPPAGAKTERgePPKSGERSGY----------SSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQ 573
Cdd:PHA03307  301 SSPGSGPAPSS--PRASSSSSSSressssstssSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSP 378

                         330       340
                  ....*....|....*....|....*..
gi 672069501  574 TAPVPMPDLKNVRSKIGSTENLKHQPG 600
Cdd:PHA03307  379 AASAGRPTRRRARAAVAGRARRRDATG 405
PHA03378 PHA03378
EBNA-3B; Provisional
 387-580 4.18e-05

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 47.37  E-value: 4.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 387 TSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPS---SPAVCPEPATSPKYVSSVTPRNGSPgtkqmklkgadgkTGAKIA 463
Cdd:PHA03378 618 TSAPRQWPMPLRPIPMRPLRMQPITFNVLVFPTphqPPQVEITPYKPTWTQIGHIPYQPSP-------------TGANTM 684

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 464 TPRGAAtPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGAKTeRGEPPKSGERSGYSSPGSPGTPGSRSRTPS 543
Cdd:PHA03378 685 LPIQWA-PGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPG-RARPPAAAPGRARPPAAAPGRARPPAAAPG 762

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 672069501 544 LPTPPTREPKKvAVVRTPPKSPSASKSRLQTAPVPMP 580
Cdd:PHA03378 763 RARPPAAAPGA-PTPQPPPQAPPAPQQRPRGAPTPQP 798
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 220-565 1.24e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 45.75  E-value: 1.24e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 220 ESPPSQASLAPGTATPQARSVSASGVSGETTSIPGFPAEGSIPLPAdffskvsAETQASPPEGPGTGPSEEGHEAAPEFT 299
Cdd:PRK07764 379 ERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPA-------PAAAPQPAPAPAPAPAPPSPAGNAPAG 451

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 300 FHVEIKASAPKEQDLEGAtvvGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGRPVSRV----PQLK-------- 367
Cdd:PRK07764 452 GAPSPPPAAAPSAQPAPA---PAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLrerwPEILaavpkrsr 528

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 368 ---------ARVAGVSKDR------TGNDEK-----------------------------------KAKTSTPSCAKTPS 397
Cdd:PRK07764 529 ktwaillpeATVLGVRGDTlvlgfsTGGLARrfaspgnaevlvtalaeelggdwqveavvgpapgaAGGEGPPAPASSGP 608

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 398 NRPCLSPTRPTPGSSDPLIKPSSPAVCPEPAtSPKYVSSVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTS 477
Cdd:PRK07764 609 PEEAARPAAPAAPAAPAAPAPAGAAAAPAEA-SAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAP 687

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 478 NATRIP---AKTTPSPKTPPGSASKQPQRKLPPAGAKTERGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKK 554
Cdd:PRK07764 688 AAPAAPagaAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPA 767

                        410
                 ....*....|.
gi 672069501 555 VAVVRTPPKSP 565
Cdd:PRK07764 768 AAPAAAPPPSP 778
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 164-581 1.49e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.55  E-value: 1.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  164 EATHQPLGTRPEDVERSHPASELLWQESPQKEAwGKDRLGSEEEVDEDITMDESSQESPPSQASLAPGTATPQARSVSAS 243
Cdd:PHA03307   66 EPPTGPPPGPGTEAPANESRSTPTWSLSTLAPA-SPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSP 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  244 GVSGETTSIPGFPAEG-------SIPLPADFFSKVSAETQASPPEGPGTGPSEEGHEAAP-EFTFHVEIKASAPKEQDLE 315
Cdd:PHA03307  145 GPPPAASPPAAGASPAavasdaaSSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPrPPRRSSPISASASSPAPAP 224

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  316 GATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAG-LPGRPvsrvpqlkarvagvskdrtgndekkaktSTPSCAK 394
Cdd:PHA03307  225 GRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPItLPTRI----------------------------WEASGWN 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  395 TPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPRNGSpgtkqmklkgaDGKTGAKIATPRGAATPGQK 474
Cdd:PHA03307  277 GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESS-----------SSSTSSSSESSRGAAVSPGP 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  475 GTSNAtripakttPSPKTPPGSASKQPQRKLPPAGAKTERGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTRepkk 554
Cdd:PHA03307  346 SPSRS--------PSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPR---- 413

                         410       420
                  ....*....|....*....|....*..
gi 672069501  555 vavvRTPPKSPSASKSRLQTAPVPMPD 581
Cdd:PHA03307  414 ----PSPLDAGAASGAFYARYPLLTPS 436
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
287-508 1.75e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.87  E-value: 1.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 287 PSEEGHEAAPeftfhveikASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAglpgrPVSRVPQL 366
Cdd:PRK12323 365 PGQSGGGAGP---------ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAA-----PARRSPAP 430

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 367 KARVAGVSKDRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATS--------PKYVSSVT 438
Cdd:PRK12323 431 EALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDdpppweelPPEFASPA 510

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 439 PRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGqkgtSNATRIPAKTTPSPKTPPGSASKQPQRKLPPA 508
Cdd:PRK12323 511 PAQPDAAPAGWVAESIPDPATADPDDAFETLAPA----PAAAPAPRAAAATEPVVAPRPPRASASGLPDM 576
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 202-572 3.31e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.39  E-value: 3.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  202 LGSEEEVDEDITMDESSQESPPSQASLAP---GTATPQARSVSASGVSGETTSIPGFPAEGSIPLPADFFSKVSAETQAS 278
Cdd:PHA03307   43 LVSDSAELAAVTVVAGAAACDRFEPPTGPppgPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPP 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  279 PPEGPGTGPSEEGHEAAPEFTFHVEIKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEAS---LLEPTDKQPAAGL 355
Cdd:PHA03307  123 PASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPsspPAEPPPSTPPAAA 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  356 PGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVS 435
Cdd:PHA03307  203 SPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRP 282

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  436 SVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNAtripAKTTPSPKTPPGSASkqpqrklPPAGAKTERG 515
Cdd:PHA03307  283 GPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSS----SSTSSSSESSRGAAV-------SPGPSPSRSP 351

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 672069501  516 EPPKSGERSGYSSPGSPGTPGSRSRTPSlPTPPTREPKKVAVVRTPPKSPSASKSRL 572
Cdd:PHA03307  352 SPSRPPPPADPSSPRKRPRPSRAPSSPA-ASAGRPTRRRARAAVAGRARRRDATGRF 407
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
387-575 4.96e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.71  E-value: 4.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 387 TSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVtPRNGSPGTKQM---KLKGADGKTGAKIA 463
Cdd:PRK12323 372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAA-PARRSPAPEALaaaRQASARGPGGAPAP 450

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 464 TPRGAATPGqKGTSNATRIPAKTTPSPKTPPGSASKQ-----------PQRKLPPAGAKTERGEP---PKSGERSGYSSP 529
Cdd:PRK12323 451 APAPAAAPA-AAARPAAAGPRPVAAAAAAAPARAAPAaapapadddppPWEELPPEFASPAPAQPdaaPAGWVAESIPDP 529

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 672069501 530 G-SPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTA 575
Cdd:PRK12323 530 AtADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDM 576
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
463-580 1.22e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 1.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 463 ATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGAKTERGEPPKSGERSGYSSPGSPGTPGSRSRTP 542
Cdd:PRK12323 372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPA 451

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 672069501 543 SLP--TPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMP 580
Cdd:PRK12323 452 PAPaaAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP 491
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 346-580 1.49e-03

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 41.87  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  346 PTDKQPAAGLPGRPVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTP-----SNRPCLSPTRPTPGSSDPLIKPSS 420
Cdd:pfam17823 145 PRAAACRANASAAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPttaasSAPATLTPARGISTAATATGHPAA 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  421 pavcpepATSPKYVSSVTPrngSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQ 500
Cdd:pfam17823 225 -------GTALAAVGNSSP---AAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARN 294

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  501 PqrkLPPAGAKTERGEPPKSGERSGYSSPGSPgTPGSRSRTPSLPTPPTREPKKVAVVRTP---PKSPSASksrlqtaPV 577
Cdd:pfam17823 295 P---AAPMGAQAQGPIIQVSTDQPVHNTAGEP-TPSPSNTTLEPNTPKSVASTNLAVVTTTkaqAKEPSAS-------PV 363


                  ...
gi 672069501  578 PMP 580
Cdd:pfam17823 364 PVL 366
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
351-580 1.56e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.14  E-value: 1.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 351 PAAGLPGRPVSRVPQLKARVAGvskdrtgndekkAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATS 430
Cdd:PRK07003 368 PGGGVPARVAGAVPAPGARAAA------------AVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPAT 435

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 431 PKYVSSVTPRNGSPGTKQMKLKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKLPPAGA 510
Cdd:PRK07003 436 ADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAA 515

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 511 KTERGEPPKSGERSGYSSPGSPG--TPGSRS----------RTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVP 578
Cdd:PRK07003 516 ASREDAPAAAAPPAPEARPPTPAaaAPAARAggaaaaldvlRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQ 595


                 ..
gi 672069501 579 MP 580
Cdd:PRK07003 596 VP 597
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 418-565 2.74e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 41.21  E-value: 2.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 418 PSSPAVCPEPATSPKYVSSVTPRNG-SPGTKQMKLKGADGKTGAKIATPRgaatPGQKGTSNATRIPAKTtpspKTPPG- 495
Cdd:PTZ00449 511 PEGPEASGLPPKAPGDKEGEEGEHEdSKESDEPKEGGKPGETKEGEVGKK----PGPAKEHKPSKIPTLS----KKPEFp 582

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 496 SASKQPQRKLPPAGAKT----ERGEPPKSGERSGYS----SPGSPGTPGSRSRTPSlPTPPT--REPKKVAVVRT--PPK 563
Cdd:PTZ00449 583 KDPKHPKDPEEPKKPKRprsaQRPTRPKSPKLPELLdipkSPKRPESPKSPKRPPP-PQRPSspERPEGPKIIKSpkPPK 661


                 ..
gi 672069501 564 SP 565
Cdd:PTZ00449 662 SP 663
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 136-321 3.22e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 3.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 136 APDSGISDWTHQQVPSMSGAPLPPQGLREATHQPLGTRPEDVERSHP-ASELLWQESPQKEAWGKDRLGSEEEVDEDITM 214
Cdd:PRK07764 616 AAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDAsDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAG 695

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 215 DESSQESP------PSQASLAPGTATPQARSVSASGVSGETTSIPGFPAEGSIPLPADFFSKVSAETQASPPEGPGTGPS 288
Cdd:PRK07764 696 AAPAQPAPapaatpPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPP 775

                        170       180       190
                 ....*....|....*....|....*....|...
gi 672069501 289 EEGHEAAPEFtfhVEIKASAPKEQDLEGATVVG 321
Cdd:PRK07764 776 PSPPSEEEEM---AEDDAPSMDDEDRRDAEEVA 805
PRK13863 PRK13863
T-DNA border endonuclease VirD2;
379-549 4.42e-03

T-DNA border endonuclease VirD2;


Pssm-ID: 237533 [Multi-domain]  Cd Length: 446  Bit Score: 40.31  E-value: 4.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 379 GNDEKKAKTSTPSCAKTPSNRPcLSPTRPTPGSSDPLIKPSSPAVCPEPATSPKYVSSVTPRNGSPGTKQMKLKGADGKT 458
Cdd:PRK13863 223 EDHREPSQSFDTSPGEAPQGEP-ESAERPEKLQNESEVRLQEPAGSSIKADARIRVSLESERRAQPSASKIPVADDFGIE 301

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 459 GAKIATPRGAATPGQKGTSNATRIPAKTTPSpktppgsaSKQPQRKLP------PAGAKTERGEPPKSGERSGYSSPGSP 532
Cdd:PRK13863 302 TSYVAEGDVRKLEGNSGTPRLATEVATHTTS--------ERQQRRKRPrddegePSGAKRTRLNGIAVGPEANAGEQDGR 373

                        170
                 ....*....|....*..
gi 672069501 533 GTPGSRSRTPSLPTPPT 549
Cdd:PRK13863 374 DDPITSPAQPPRSNPLA 390
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
279-582 4.49e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.60  E-value: 4.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 279 PPEGPGTGPSEEGHEAAPEftfhveiKASAPKEQDLEGATVVGAPAEEQKARGPSVGKGTKEASLLEPTDKQPAAGLPGR 358
Cdd:PRK07003 360 PAVTGGGAPGGGVPARVAG-------AVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAP 432

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 359 PVSRVPQLKARVAGVSKDRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDPLIKPSSPAVCPEPATSPkyvssvt 438
Cdd:PRK07003 433 PATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPA------- 505

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501 439 prngspgtkqmklKGADGKTGAKIATPRGAATPGQKGTSNATRIPAKTTPSPKTPPGSASKQPQRKlppAGAK--TERGE 516
Cdd:PRK07003 506 -------------AVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAALDVLRN---AGMRvsSDRGA 569

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 672069501 517 PPKSGERSGYSSPGSPGTPGSRsrtPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMPDL 582
Cdd:PRK07003 570 RAAAAAKPAAAPAAAPKPAAPR---VAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPPPWEDI 632
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 34-264 5.12e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 40.45  E-value: 5.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501   34 ESPPQPPADDGSEEPGSETSDAKSTPTAEDVTAPLVEERAPDKQ-----ATAQSHTEIP-EGTTAEEAGIGDTPNMEDQA 107
Cdd:PRK10263  342 QTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQyaqpaVQYNEPLQQPvQPQQPYYAPAAEQPAQQPYY 421

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  108 AGHVTQEPQKVEIFSQSllVEPGRREGQAPDSGISDWTHQ------QVPSMSGAPLPPQGLREATHQPLGTRPED-VERS 180
Cdd:PRK10263  422 APAPEQPAQQPYYAPAP--EQPVAGNAWQAEEQQSTFAPQstyqteQTYQQPAAQEPLYQQPQPVEQQPVVEPEPvVEET 499

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  181 HPASELLW--QESPQKEAWGKDRLGS-----EEEVDEDITMDESSqeSPPSQASLAPGTATPQARSVSAS-------GVS 246
Cdd:PRK10263  500 KPARPPLYyfEEVEEKRAREREQLAAwyqpiPEPVKEPEPIKSSL--KAPSVAAVPPVEAAAAVSPLASGvkkatlaTGA 577

                         250
                  ....*....|....*....
gi 672069501  247 GETTSIPGF-PAEGSIPLP 264
Cdd:PRK10263  578 AATVAAPVFsLANSGGPRP 596
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 376-568 7.94e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 39.90  E-value: 7.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  376 DRTGNDEKKAKTSTPSCAKTPSNRPCLSPTRPTPGSSDplikpsspAVCPEPATSPKYVSSVTPrngSPGTKQmklKGAD 455
Cdd:pfam05109 435 NTTGFAAPNTTTGLPSSTHVPTNLTAPASTGPTVSTAD--------VTSPTPAGTTSGASPVTP---SPSPRD---NGTE 500

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 672069501  456 GKTGAKIATPRGAATPGQKGTSNAtriPAKTTPSP--------KTPPGSASKQP----QRKLPPAGAKTERGEPPKSGER 523
Cdd:pfam05109 501 SKAPDMTSPTSAVTTPTPNATSPT---PAVTTPTPnatsptlgKTSPTSAVTTPtpnaTSPTPAVTTPTPNATIPTLGKT 577

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 672069501  524 SGYSSPGSPgTPGSRSRTPSLPTPPTREPK-------KVAVVRTPPKSPSAS 568
Cdd:pfam05109 578 SPTSAVTTP-TPNATSPTVGETSPQANTTNhtlggtsSTPVVTSPPKNATSA 628
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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