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Conserved domains on  [gi|578835604|ref|XP_006723714|]
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protein sel-1 homolog 2 isoform X7 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11434433)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
282-476 2.94e-48

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 168.57  E-value: 2.94e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 282 WDIYQYYKFLAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKY 361
Cdd:COG0790   48 AAAAAAAAAAAAAGGAEAQYNLGLMYAEGR-GVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEW 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 362 FSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 441
Cdd:COG0790  126 YEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQG 205

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 578835604 442 QPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 476
Cdd:COG0790  206 DADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
124-331 1.59e-19

TPR repeat [General function prediction only];


:

Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 88.06  E-value: 1.59e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 124 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 203
Cdd:COG0790   80 PKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 204 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVadyiadtfeksegvpvekvrlterpenlssnseildwd 283
Cdd:COG0790  160 EWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKA-------------------------------------- 201

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 578835604 284 iyqyykflAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKA 331
Cdd:COG0790  202 --------AEQGDADAQYNLGRLYLNGE-GVEKDLEKALRWLRKAAEQ 240
Mplasa_alph_rch super family cl37461
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 18-128 1.00e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


The actual alignment was detected with superfamily member TIGR04523:

Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 1.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604   18 IKTIKAEEHNKRQKERNVTTQVS-----VNEIKQYLSHILEQRTSSNV--------INKRENLLEKKKNQRKIRIKGIQN 84
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQISqnnkiISQLNEQISQLKKELTNSESensekqreLEEKQNEIEKLKKENQSYKQEIKN 388

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 578835604   85 kdiLKRNKNHLQKQAEKNftDEGDQLFKMGIKVLQQSKSQKQKE 128
Cdd:TIGR04523 389 ---LESQINDLESKIQNQ--EKLNQQKDEQIKKLQQEKELLEKE 427
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
282-476 2.94e-48

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 168.57  E-value: 2.94e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 282 WDIYQYYKFLAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKY 361
Cdd:COG0790   48 AAAAAAAAAAAAAGGAEAQYNLGLMYAEGR-GVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEW 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 362 FSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 441
Cdd:COG0790  126 YEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQG 205

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 578835604 442 QPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 476
Cdd:COG0790  206 DADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
124-331 1.59e-19

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 88.06  E-value: 1.59e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 124 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 203
Cdd:COG0790   80 PKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 204 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVadyiadtfeksegvpvekvrlterpenlssnseildwd 283
Cdd:COG0790  160 EWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKA-------------------------------------- 201

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 578835604 284 iyqyykflAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKA 331
Cdd:COG0790  202 --------AEQGDADAQYNLGRLYLNGE-GVEKDLEKALRWLRKAAEQ 240
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 407-441 2.22e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 44.47  E-value: 2.22e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 578835604   407 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 441
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 371-405 5.83e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 43.28  E-value: 5.83e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 578835604  371 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 405
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 18-128 1.00e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 1.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604   18 IKTIKAEEHNKRQKERNVTTQVS-----VNEIKQYLSHILEQRTSSNV--------INKRENLLEKKKNQRKIRIKGIQN 84
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQISqnnkiISQLNEQISQLKKELTNSESensekqreLEEKQNEIEKLKKENQSYKQEIKN 388

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 578835604   85 kdiLKRNKNHLQKQAEKNftDEGDQLFKMGIKVLQQSKSQKQKE 128
Cdd:TIGR04523 389 ---LESQINDLESKIQNQ--EKLNQQKDEQIKKLQQEKELLEKE 427
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 216-247 8.28e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 34.46  E-value: 8.28e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 578835604   216 MSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
 
Name Accession Description Interval E-value
TPR COG0790
TPR repeat [General function prediction only];
282-476 2.94e-48

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 168.57  E-value: 2.94e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 282 WDIYQYYKFLAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKY 361
Cdd:COG0790   48 AAAAAAAAAAAAAGGAEAQYNLGLMYAEGR-GVPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLG-VPQDYAKALEW 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 362 FSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 441
Cdd:COG0790  126 YEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQG 205

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 578835604 442 QPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCEL 476
Cdd:COG0790  206 DADAQYNLGRLYLNGEGVEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
316-478 1.78e-39

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 144.69  E-value: 1.78e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 316 QDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEAL 395
Cdd:COG0790   45 AGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRG-VPKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKAL 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 396 KYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCE 475
Cdd:COG0790  124 EWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAE 203


                 ...
gi 578835604 476 LGH 478
Cdd:COG0790  204 QGD 206
TPR COG0790
TPR repeat [General function prediction only];
128-437 1.28e-33

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 128.51  E-value: 1.28e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 128 EEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKALIYYT 207
Cdd:COG0790   12 AAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFE 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 208 FGSAGGNMMSQMILGYRYLSGinvlqncevalsyykkvadyiadtfeksegvpvekvrlterpenlssnseildwdiyqy 287
Cdd:COG0790   92 KAAEQGDAEAQYNLGLMYEEG----------------------------------------------------------- 112

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 288 ykflaergdvqiqvslgqlhligrKGLDQDYYKALHYFLKAAKAGSANAMAFIGKMYLEGNaAVPQNNATAFKYFSMAAS 367
Cdd:COG0790  113 ------------------------LGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGE-GVPKDPAKAAEWYRKAAE 167

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 368 KGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLA 437
Cdd:COG0790  168 QGDADAQYNLGVLYENGRGVPKDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEGVEKDLEKALRWLRKA 237
TPR COG0790
TPR repeat [General function prediction only];
326-548 9.41e-31

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 120.42  E-value: 9.41e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 326 LKAAKAGSANAMAFIGKMYLEGNAAVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 405
Cdd:COG0790   18 LAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVPKDYEKALEWFEKAAEQG 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 406 WPDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCELGH-WAEKFL 484
Cdd:COG0790   98 DAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAAEWYRKAAEQGDaDAQYNL 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578835604 485 TAYFAYKDG---DIDSSLVQYALLAEMGYEVAQSNSAFILESKKAnileKEKMYPMALLLWNRAAIQ 548
Cdd:COG0790  178 GVLYENGRGvpkDPAKALEWYRKAAEQGDADAQYNLGRLYLNGEG----VEKDLEKALRWLRKAAEQ 240
TPR COG0790
TPR repeat [General function prediction only];
345-554 7.93e-20

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 88.83  E-value: 7.93e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 345 LEGNAAVPQNNATAFKYFSMAASKGNAIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKGWPDAQFQLGFMYYSGSGIW 424
Cdd:COG0790    1 LALAAAAAAAAAAAAAALAAAAAAAGAAAAAAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGLMYAEGRGVP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 425 KDYKLAFKYFYLASQSGQPLAIYYLAKMYATGTGVVRSCRTAVELYKGVCELGH-WAEKFLTAYFAYKDG---DIDSSLV 500
Cdd:COG0790   81 KDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDaDAQYNLGLLYLNGEGvpkDPAKAAE 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 578835604 501 QYALLAEMGYEVAQSNSAFILESKKanilEKEKMYPMALLLWNRAAIQGHSLGQ 554
Cdd:COG0790  161 WYRKAAEQGDADAQYNLGVLYENGR----GVPKDPAKALEWYRKAAEQGDADAQ 210
TPR COG0790
TPR repeat [General function prediction only];
124-331 1.59e-19

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 88.06  E-value: 1.59e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 124 QKQKEEAYLLFAKAADMGNLKAMEKMADALLFGNFGVQNITAAIQLYESLAKEGSCKAQNALGFLSSYGIGMEYDQAKAL 203
Cdd:COG0790   80 PKDYEKALEWFEKAAEQGDAEAQYNLGLMYEEGLGVPQDYAKALEWYEKAAEQGDADAQYNLGLLYLNGEGVPKDPAKAA 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604 204 IYYTFGSAGGNMMSQMILGYRYLSGINVLQNCEVALSYYKKVadyiadtfeksegvpvekvrlterpenlssnseildwd 283
Cdd:COG0790  160 EWYRKAAEQGDADAQYNLGVLYENGRGVPKDPAKALEWYRKA-------------------------------------- 201

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 578835604 284 iyqyykflAERGDVQIQVSLGQLHLIGRkGLDQDYYKALHYFLKAAKA 331
Cdd:COG0790  202 --------AEQGDADAQYNLGRLYLNGE-GVEKDLEKALRWLRKAAEQ 240
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 407-441 2.22e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 44.47  E-value: 2.22e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 578835604   407 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 441
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 371-405 3.38e-06

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 43.70  E-value: 3.38e-06
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 578835604   371 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 405
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELG 35
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 371-405 5.83e-06

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 43.28  E-value: 5.83e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 578835604  371 AIGLHGLGLLYFHGKGVPLNYAEALKYFQKAAEKG 405
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 443-478 9.79e-05

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 39.85  E-value: 9.79e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 578835604   443 PLAIYYLAKMYATGTGVVRSCRTAVELYKGVCELGH 478
Cdd:smart00671   1 AEAQYNLGQMYEYGLGVPKDLEKALEYYKKAAELGN 36
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 18-128 1.00e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 1.00e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578835604   18 IKTIKAEEHNKRQKERNVTTQVS-----VNEIKQYLSHILEQRTSSNV--------INKRENLLEKKKNQRKIRIKGIQN 84
Cdd:TIGR04523 309 NKELKSELKNQEKKLEEIQNQISqnnkiISQLNEQISQLKKELTNSESensekqreLEEKQNEIEKLKKENQSYKQEIKN 388

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 578835604   85 kdiLKRNKNHLQKQAEKNftDEGDQLFKMGIKVLQQSKSQKQKE 128
Cdd:TIGR04523 389 ---LESQINDLESKIQNQ--EKLNQQKDEQIKKLQQEKELLEKE 427
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 407-441 1.59e-04

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 39.04  E-value: 1.59e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 578835604  407 PDAQFQLGFMYYSGSGIWKDYKLAFKYFYLASQSG 441
Cdd:pfam08238   1 AEAQYRLGYLYLYGLGVPKDPEKALEWYEKAAELG 35
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 334-370 2.83e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 35.61  E-value: 2.83e-03
                           10        20        30
                   ....*....|....*....|....*....|....*..
gi 578835604   334 ANAMAFIGKMYLEGNAaVPQNNATAFKYFSMAASKGN 370
Cdd:smart00671   1 AEAQYNLGQMYEYGLG-VPKDLEKALEYYKKAAELGN 36
SEL1 smart00671
Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.
 216-247 8.28e-03

Sel1-like repeats; These represent a subfamily of TPR (tetratricopeptide repeat) sequences.


Pssm-ID: 214772 [Multi-domain]  Cd Length: 36  Bit Score: 34.46  E-value: 8.28e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 578835604   216 MSQMILGYRYLSGINVLQNCEVALSYYKKVAD 247
Cdd:smart00671   2 EAQYNLGQMYEYGLGVPKDLEKALEYYKKAAE 33
Sel1 pfam08238
Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.
 334-369 9.94e-03

Sel1 repeat; This short repeat is found in the Sel1 protein. It is related to TPR repeats.


Pssm-ID: 429881 [Multi-domain]  Cd Length: 35  Bit Score: 34.03  E-value: 9.94e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 578835604  334 ANAMAFIGKMYLEGnAAVPQNNATAFKYFSMAASKG 369
Cdd:pfam08238   1 AEAQYRLGYLYLYG-LGVPKDPEKALEWYEKAAELG 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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