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Conserved domains on  [gi|568930825|ref|XP_006538728|]
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NAD kinase isoform X2 [Mus musculus]

Protein Classification

diacylglycerol kinase catalytic domain-containing protein( domain architecture ID 546)

diacylglycerol kinase catalytic domain-containing protein is involved in the conversion of diacylglycerol (DAG) to phosphatidic acid (PA), utilizing ATP as a source of the phosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DAGK_cat super family cl01255
Diacylglycerol kinase catalytic domain; Diacylglycerol (DAG) is a second messenger that acts ...
 98-310 1.92e-47

Diacylglycerol kinase catalytic domain; Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologs. YegS is the Escherichia coli protein in this family whose crystal structure reveals an active site in the inter-domain cleft formed by four conserved sequence motifs, revealing a novel metal-binding site. The residues of this site are conserved across the family.


The actual alignment was detected with superfamily member PLN02935:

Pssm-ID: 445337 [Multi-domain]  Cd Length: 508  Bit Score: 166.93  E-value: 1.92e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825  98 LTWNKSPKSVLVIKKIRDASLLQPFKELCIYLMEENNMIVYVEKKVLEDpAIVSDENFGPVKKkfCTFREDYDDISNQID 177
Cdd:PLN02935 188 LKWESDPQTVLIITKPNSTSVRVLCAEMVRWLREQKGLNIYVEPRVKKE-LLSESSYFNFVQT--WEDEKEILLLHTKVD 264

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 178 FIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKEPRdkktaih 257
Cdd:PLN02935 265 LVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGPISITLRHRLQCHIIRDAA------- 337

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 568930825 258 nglsENGLDTEGgkqamQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGD 310
Cdd:PLN02935 338 ----KNEYETEE-----PILVLNEVTIDRGISSFLTNLECYCDNSFVTCVQGD 381
 
Name Accession Description Interval E-value
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 98-310 1.92e-47

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 166.93  E-value: 1.92e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825  98 LTWNKSPKSVLVIKKIRDASLLQPFKELCIYLMEENNMIVYVEKKVLEDpAIVSDENFGPVKKkfCTFREDYDDISNQID 177
Cdd:PLN02935 188 LKWESDPQTVLIITKPNSTSVRVLCAEMVRWLREQKGLNIYVEPRVKKE-LLSESSYFNFVQT--WEDEKEILLLHTKVD 264

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 178 FIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKEPRdkktaih 257
Cdd:PLN02935 265 LVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGPISITLRHRLQCHIIRDAA------- 337

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 568930825 258 nglsENGLDTEGgkqamQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGD 310
Cdd:PLN02935 338 ----KNEYETEE-----PILVLNEVTIDRGISSFLTNLECYCDNSFVTCVQGD 381
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
105-310 9.12e-28

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 109.07  E-value: 9.12e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 105 KSVLVIKKIRDASLLQPFKELCIYLmEENNMIVYVEKKVLEDPAivsdenfgpvkkkfctfreDYDDISNQIDFIICLGG 184
Cdd:COG0061    2 KRIAIVAKPGKPEALEAAEELAELL-EERGIEVVLDEDTAVPGV-------------------PLEELGEEADLVIVLGG 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 185 DGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVvkeprdkktaihnglseng 264
Cdd:COG0061   62 DGTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATV------------------- 122

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 568930825 265 ldTEGGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGD 310
Cdd:COG0061  123 --DRDGEVVHEALALNEVVVLRGSIARMIELEVYIDGEFLEEFRGD 166
NAD_kinase pfam01513
ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 107-230 6.85e-17

ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.


Pssm-ID: 426300 [Multi-domain]  Cd Length: 128  Bit Score: 75.86  E-value: 6.85e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825  107 VLVIKKIRDASLLQPFKELCIYLMEENNMIVYVEKKV-------LEDPAIVSDENFGPVK---KKFCTFREdyddisNQI 176
Cdd:pfam01513   1 VGIVVNPDKKEALERAREVARWLLDRLGITVTVEEKMgeslafaAGDRPEVIGCLKKVVDdtrRATRAFAD------AGV 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568930825  177 DFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIE 230
Cdd:pfam01513  75 DLIIVLGGDGTALRAARLLQKAVIPILGVNTGVLGFLTEFEPEAAFELLERLLE 128
 
Name Accession Description Interval E-value
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 98-310 1.92e-47

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 166.93  E-value: 1.92e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825  98 LTWNKSPKSVLVIKKIRDASLLQPFKELCIYLMEENNMIVYVEKKVLEDpAIVSDENFGPVKKkfCTFREDYDDISNQID 177
Cdd:PLN02935 188 LKWESDPQTVLIITKPNSTSVRVLCAEMVRWLREQKGLNIYVEPRVKKE-LLSESSYFNFVQT--WEDEKEILLLHTKVD 264

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 178 FIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKEPRdkktaih 257
Cdd:PLN02935 265 LVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGPISITLRHRLQCHIIRDAA------- 337

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 568930825 258 nglsENGLDTEGgkqamQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGD 310
Cdd:PLN02935 338 ----KNEYETEE-----PILVLNEVTIDRGISSFLTNLECYCDNSFVTCVQGD 381
PLN02727 PLN02727
NAD kinase
 96-317 2.13e-44

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 162.36  E-value: 2.13e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825  96 QRLTWNKSPKSVLVIKKIRDAsLLQPFKELCIYLMEENNMIVYVEKKVLEDPAIVSdeNFGPVKkkfcTF-REDYDDISN 174
Cdd:PLN02727 670 QMLMWKSTPKTVLLLKKLGQE-LMEEAKEVASFLYHQEKMNVLVEPDVHDIFARIP--GFGFVQ----TFySQDTSDLHE 742

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 175 QIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAA-----VILRSRLKVRVVKep 249
Cdd:PLN02727 743 RVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVIHGNNTldgvyITLRMRLRCEIFR-- 820

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568930825 250 rdkktaihNGlsengldteggkQAMQ---YQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDDYAV---TGS 317
Cdd:PLN02727 821 --------NG------------KAMPgkvFDVLNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVatpTGS 874
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
105-310 9.12e-28

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 109.07  E-value: 9.12e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 105 KSVLVIKKIRDASLLQPFKELCIYLmEENNMIVYVEKKVLEDPAivsdenfgpvkkkfctfreDYDDISNQIDFIICLGG 184
Cdd:COG0061    2 KRIAIVAKPGKPEALEAAEELAELL-EERGIEVVLDEDTAVPGV-------------------PLEELGEEADLVIVLGG 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 185 DGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVvkeprdkktaihnglseng 264
Cdd:COG0061   62 DGTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATV------------------- 122

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 568930825 265 ldTEGGKQAMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGD 310
Cdd:COG0061  123 --DRDGEVVHEALALNEVVVLRGSIARMIELEVYIDGEFLEEFRGD 166
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
100-322 1.92e-18

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 85.94  E-value: 1.92e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 100 WNKSPKSVLVIKKIRDASLLQPFKELCIYLmEENNMIVYVEKKVLEdpaivsdenfgPVKKKFCTFREDYDDISNqIDFI 179
Cdd:PRK14076 286 WRIKPTKFGIVSRIDNEEAINLALKIIKYL-DSKGIPYELESFLYN-----------KLKNRLNEECNLIDDIEE-ISHI 352

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 180 ICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKEPRDKKTaihng 259
Cdd:PRK14076 353 ISIGGDGTVLRASKLVNGEEIPIICINMGTVGFLTEFSKEEIFKAIDSIISGEYEIEKRTKLSGFILKDGHQNIL----- 427

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568930825 260 lsengldteggkqamqYQVLNEVVI-DRGPSSYLsNVDVYLDGHLITTVQGDDYAV---TGSQEHGM 322
Cdd:PRK14076 428 ----------------PSALNEVVItTKNPAKML-HFEVYVNGELVEEVRADGIIIstpTGSTAYSL 477
NAD_kinase pfam01513
ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 107-230 6.85e-17

ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.


Pssm-ID: 426300 [Multi-domain]  Cd Length: 128  Bit Score: 75.86  E-value: 6.85e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825  107 VLVIKKIRDASLLQPFKELCIYLMEENNMIVYVEKKV-------LEDPAIVSDENFGPVK---KKFCTFREdyddisNQI 176
Cdd:pfam01513   1 VGIVVNPDKKEALERAREVARWLLDRLGITVTVEEKMgeslafaAGDRPEVIGCLKKVVDdtrRATRAFAD------AGV 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 568930825  177 DFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIE 230
Cdd:pfam01513  75 DLIIVLGGDGTALRAARLLQKAVIPILGVNTGVLGFLTEFEPEAAFELLERLLE 128
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 120-317 3.29e-14

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 71.88  E-value: 3.29e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 120 QPFKELCIYLMEENNMIVYVEKKVLEdpAIVSDENFGPVKKKFCTFredyDDISNQIDFIICLGGDGTLLYASSLFQGSV 199
Cdd:PRK01911  15 SPYIQELFDELEERGAEVLIEEKFLD--FLKQDLKFHPSYDTFSDN----EELDGSADMVISIGGDGTFLRTATYVGNSN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 200 PPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRvvkeprdkktaihnglSENGLDTEggkqaMQYqVL 279
Cdd:PRK01911  89 IPILGINTGRLGFLATVSKEEIEETIDELLNGDYTIEERSLLQLE----------------SNPKLFGE-----LNF-AL 146

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 568930825 280 NEVVIDRGPSSYLSNVDVYLDGHLITTVQGDDYAV---TGS 317
Cdd:PRK01911 147 NEIAILKRDTSSMITVHTYLNGEYLNSYWADGLIVatpTGS 187
ppnK PRK03708
NAD(+) kinase;
160-322 7.49e-13

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 67.43  E-value: 7.49e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 160 KKFCTFRE-DYDDISN-QIDFIICLGGDGTLLYASSLFQGSVpPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVil 237
Cdd:PRK03708  40 EHLPEFSEeDVLPLEEmDVDFIIAIGGDGTILRIEHKTKKDI-PILGINMGTLGFLTEVEPEETFFALSRLLEGDYFI-- 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 238 RSRLKVRVvkeprdkktaIHNGlsENGLDteggkqamqyqVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDDYAV--- 314
Cdd:PRK03708 117 DERIKLRV----------YING--ENVPD-----------ALNEVVILTGIPGKIIHLKYYVDGELADEVRADGLIIstp 173


                 ....*...
gi 568930825 315 TGSQEHGM 322
Cdd:PRK03708 174 TGSTAYAM 181
ppnK PRK01231
NAD(+) kinase;
177-317 1.46e-11

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 63.82  E-value: 1.46e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 177 DFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVvkepRDKKTAI 256
Cdd:PRK01231  64 DLVIVVGGDGSLLGAARALARHNVPVLGINRGRLGFLTDIRPDELEFKLAEVLDGHYQEEERFLLEAEV----RRGGEVI 139

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568930825 257 HNGLSengldteggkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDDYAV---TGS 317
Cdd:PRK01231 140 GQGDA-----------------LNDVVLHPGKSTRMIEFELYIDGQFVCSQRSDGLIVstpTGS 186
ppnK PRK02155
NAD kinase;
168-317 2.17e-10

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 60.34  E-value: 2.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 168 DYDDISNQIDFIICLGGDGTLL-YASSLFQGSVPPVMAFHlGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVV 246
Cdd:PRK02155  56 TPEEIGARADLAVVLGGDGTMLgIGRQLAPYGVPLIGINH-GRLGFITDIPLDDMQETLPPMLAGNYEEEERMLLEARVV 134

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568930825 247 kepRDKKTaIHNGLSengldteggkqamqyqvLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDDYAV---TGS 317
Cdd:PRK02155 135 ---RDGEP-IFHALA-----------------FNDVVVNRSGFSGMVELRVSVDGRFMYNQRSDGLIVatpTGS 187
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 119-317 1.11e-08

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 55.25  E-value: 1.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 119 LQPFKELCIYLMEENNMIVYVEKKVLEDPAIVSDENFGpvkkkfCTFReDYDDISNQIDFIICLGGDGTLLYASSLFQGS 198
Cdd:PRK04539  19 IQDTAHTLITFLKQHGFTVYLDEVGIKEGCIYTQDTVG------CHIV-NKTELGQYCDLVAVLGGDGTFLSVAREIAPR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 199 VPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKEprdkktaihnglsengldtegGKQAMQYQV 278
Cdd:PRK04539  92 AVPIIGINQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIRE---------------------GKTAERALA 150

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 568930825 279 LNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDDYAV---TGS 317
Cdd:PRK04539 151 LNDAVLSRGGAGQMIEFEVFVNREFVYTQRSDGLIVstpTGS 192
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 279-323 2.06e-06

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 46.14  E-value: 2.06e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 568930825  279 LNEVVIDRGPSSYLSNVDVYLDGHLITTVQGDDYAV---TGSQEHGMG 323
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVstpTGSTAYSLS 48
pnk PRK14077
NAD(+) kinase;
170-310 3.13e-06

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 47.85  E-value: 3.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 170 DDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKep 249
Cdd:PRK14077  59 DELFKISDFLISLGGDGTLISLCRKAAEYDKFVLGIHAGHLGFLTDITVDEAEKFFQAFFQGEFEIEKPYMLSVFLEK-- 136

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568930825 250 RDKKTaihnglsengldteggkqaMQYQVLNEVVIDRGPSSYLSNVDVYLDGHLITTVQGD 310
Cdd:PRK14077 137 KQGKI-------------------LEKLAFNDVVISKNNQASMAHIEAFLNEKYFNEYFGD 178
ppnK PRK02649
NAD(+) kinase;
176-309 7.27e-06

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 46.90  E-value: 7.27e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 176 IDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTpfnfENFQSQVN----QVIEGNAAVILRSRLKVRVVKEprd 251
Cdd:PRK02649  69 MKFAIVLGGDGTVLSAARQLAPCGIPLLTINTGHLGFLT----EAYLNQLDeaidQVLAGQYTIEERTMLTVSVMRG--- 141

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568930825 252 kKTAIHNGLSengldteggkqamqyqvLNEVVIDRGPSSYL----------SNVDVYLDGHLITTVQG 309
Cdd:PRK02649 142 -DQLRWEALS-----------------LNEMVLHREPLTSMchfeiaigrhAPVDIAADGVILSTPTG 191
ppnK PRK02645
NAD(+) kinase;
173-317 1.08e-05

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 46.44  E-value: 1.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 173 SNQIDFIICLGGDGTLLYAS-SLFQGSVpPVMAFHL-GSLGFLT-PFNFENFQSQVNQVIEGNAAVILRSRLKVRVVKEP 249
Cdd:PRK02645  55 SELIDLAIVLGGDGTVLAAArHLAPHDI-PILSVNVgGHLGFLThPRDLLQDESVWDRLQEDRYAIERRMMLQARVFEGD 133

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568930825 250 RDKKTAIhnglSENgldteggkqamqYQVLNE-----VVIDRGPSSYLsnvDVYLDGHLITTVQGDDYAV---TGS 317
Cdd:PRK02645 134 RSNEEPV----SES------------YYALNDfylkpASEDRSPTCIL---ELEIDGEVVDQYQGDGLIVstpTGS 190
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 143-245 1.97e-04

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 42.60  E-value: 1.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 143 VLEDPAIVSDENFGPV---KKKFCTFREDyDDISNQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFLTPFNFE 219
Cdd:PRK03372  38 RVLDAEAVDLGATHPApddFRAMEVVDAD-PDAADGCELVLVLGGDGTILRAAELARAADVPVLGVNLGHVGFLAEAEAE 116

                         90       100
                 ....*....|....*....|....*.
gi 568930825 220 NFQSQVNQVIEGNAAVILRSRLKVRV 245
Cdd:PRK03372 117 DLDEAVERVVDRDYRVEERMTLDVTV 142
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 169-213 2.20e-03

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 39.03  E-value: 2.20e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 568930825 169 YDDIS-NQIDFIICLGGDGTLLYASSLFQGSVPPVMAFHLGSLGFL 213
Cdd:PRK04761  18 YGDVPiEEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFL 63
PLN02929 PLN02929
NADH kinase
 163-245 2.40e-03

NADH kinase


Pssm-ID: 215502 [Multi-domain]  Cd Length: 301  Bit Score: 39.25  E-value: 2.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568930825 163 CTFREDYDDISNQIDFIICLGGDGTLLYASSLFQGSVPPvmafhLG----------------------SLGFLTPFNFEN 220
Cdd:PLN02929  52 CVLRNELSQPIRDVDLVVAVGGDGTLLQASHFLDDSIPV-----LGvnsdptqkdeveeysdefdarrSTGHLCAATAED 126

                         90       100
                 ....*....|....*....|....*
gi 568930825 221 FQSQVNQVIEGNAAVILRSRLKVRV 245
Cdd:PLN02929 127 FEQVLDDVLFGRLKPTELSRISTVV 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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