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Conserved domains on  [gi|568920993|ref|XP_006535569|]
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PEX5-related protein isoform X14 [Mus musculus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11929115)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|10517866
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
333-602 8.58e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 97.77  E-value: 8.58e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 333 DPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKykylvknkk 412
Cdd:COG0457    4 DPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPD--------- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 413 gspgltrrmskspvdssvlegvkelyleaahqngdmiDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLG 492
Cdd:COG0457   75 -------------------------------------DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLG 117

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 493 ATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALR 572
Cdd:COG0457  118 LALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLL 197

                        250       260       270
                 ....*....|....*....|....*....|
gi 568920993 573 IALSLMDQPELFQAANLGDLDVLLRAFNLD 602
Cdd:COG0457  198 ALLLALEQALRKKLAILTLAALAELLLLAL 227
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 209-404 1.05e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.08  E-value: 1.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 209 ASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSAs 288
Cdd:COG3914   20 AAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEAL- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 289 ekGYYFHT--ENPfKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLEL 366
Cdd:COG3914   99 --ALYRRAlaLNP-DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALEL 175

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 568920993 367 QPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKY 404
Cdd:COG3914  176 DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDN 213
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
333-602 8.58e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 97.77  E-value: 8.58e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 333 DPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKykylvknkk 412
Cdd:COG0457    4 DPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPD--------- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 413 gspgltrrmskspvdssvlegvkelyleaahqngdmiDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLG 492
Cdd:COG0457   75 -------------------------------------DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLG 117

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 493 ATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALR 572
Cdd:COG0457  118 LALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLL 197

                        250       260       270
                 ....*....|....*....|....*....|
gi 568920993 573 IALSLMDQPELFQAANLGDLDVLLRAFNLD 602
Cdd:COG0457  198 ALLLALEQALRKKLAILTLAALAELLLLAL 227
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 314-551 2.29e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 63.56  E-value: 2.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  314 LKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYtntSHQQDACEA 393
Cdd:TIGR02917 578 LGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAY---AVMKNYAKA 654

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  394 LKnwikqnpKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKELY--LEAAHQNgdmiDPDLQTGLGVLFHLSGEFNRAI 471
Cdd:TIGR02917 655 IT-------SLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAksLQKQHPK----AALGFELEGDLYLRQKDYPAAI 723

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  472 DAFNAALTVRPEDYSLWNRLGATLANGDRSeEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRK 551
Cdd:TIGR02917 724 QAYRKALKRAPSSQNAIKLHRALLASGNTA-EAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPD 802
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 209-404 1.05e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.08  E-value: 1.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 209 ASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSAs 288
Cdd:COG3914   20 AAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEAL- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 289 ekGYYFHT--ENPfKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLEL 366
Cdd:COG3914   99 --ALYRRAlaLNP-DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALEL 175

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 568920993 367 QPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKY 404
Cdd:COG3914  176 DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDN 213
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 325-539 4.14e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 45.70  E-value: 4.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 325 FMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNL-KALMAL--------AVSYTNTshqqdACEALK 395
Cdd:cd24142   22 FLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyEKYLYLgqlsggeeALQYYEK-----GIEILE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 396 NWIKQNPKYKYLvkNKKGSPGLTRRMskspvdSSVLEGVKELYL-------------EAAHQNGDMIDPD----LQTgLG 458
Cdd:cd24142   97 EELQALQAASAE--AEEEAEELKRKL------SSALCALAEIYMtdlcdepdaeqrcEELITKALELDPTnpeaLQT-LA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 459 VLfHLS-GEFNRAIDAFNAAltvrpedYSLWNRLGATLANGDRSEEAVEAYTRALEiqpgfirSRYNLGISCINLGAYRE 537
Cdd:cd24142  168 SL-RISqQRPDEAKEALRRS-------LELWKDLKEEDEEEAEEDEAEEEDVPSYE-------FRISLAKLLIELEMYEE 232


                 ..
gi 568920993 538 AV 539
Cdd:cd24142  233 AL 234
TPR_12 pfam13424
Tetratricopeptide repeat;
486-551 8.52e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 8.52e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568920993  486 SLWNRLGATLANGDRSEEAVEAYTRALEIQ--------PGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRK 551
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
PRK11189 PRK11189
lipoprotein NlpI; Provisional
 457-506 1.81e-03

lipoprotein NlpI; Provisional


Pssm-ID: 236875 [Multi-domain]  Cd Length: 296  Bit Score: 40.64  E-value: 1.81e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 568920993 457 LGVLFHLSGEFNRAIDAFNAALTVRPE-DYSLWNRlGATLANGDRSEEAVE 506
Cdd:PRK11189 104 LGIYLTQAGNFDAAYEAFDSVLELDPTyNYAYLNR-GIALYYGGRYELAQD 153
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
333-602 8.58e-23

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 97.77  E-value: 8.58e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 333 DPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKykylvknkk 412
Cdd:COG0457    4 DPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPD--------- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 413 gspgltrrmskspvdssvlegvkelyleaahqngdmiDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLG 492
Cdd:COG0457   75 -------------------------------------DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLG 117

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 493 ATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALR 572
Cdd:COG0457  118 LALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLL 197

                        250       260       270
                 ....*....|....*....|....*....|
gi 568920993 573 IALSLMDQPELFQAANLGDLDVLLRAFNLD 602
Cdd:COG0457  198 ALLLALEQALRKKLAILTLAALAELLLLAL 227
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 340-549 1.97e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 79.77  E-value: 1.97e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 340 WQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKykylvknkkgSPGLTR 419
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPD----------RAEALL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 420 RMSKSPVDSSVLEGVKELYLEAAHQNGDmiDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGD 499
Cdd:COG2956   81 ELAQDYLKAGLLDRAEELLEKLLELDPD--DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQG 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 568920993 500 RSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQ 549
Cdd:COG2956  159 DYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD 208
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
449-549 6.25e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 77.74  E-value: 6.25e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 449 IDPDL---QTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNL 525
Cdd:COG0457    3 LDPDDaeaYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                         90       100
                 ....*....|....*....|....
gi 568920993 526 GISCINLGAYREAVSNFLTALSLQ 549
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELD 106
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
457-601 6.29e-16

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 77.26  E-value: 6.29e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 457 LGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYR 536
Cdd:COG4785   79 RGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYE 158

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568920993 537 EAVSNFLTALSLQRKSRNQqqvphpaisgNIWAALRI-------ALSLMDQPELFQAANLGDLDVLLRAFNL 601
Cdd:COG4785  159 LAIADLEKALELDPNDPER----------ALWLYLAErkldpekALALLLEDWATAYLLQGDTEEARELFKL 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 305-549 3.93e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 75.92  E-value: 3.93e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 305 GAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNT 384
Cdd:COG2956   10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 385 SHQQDAcEALknwikqnpkYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKELYLEAAHQNGDmiDPDLQTGLGVLFHLS 464
Cdd:COG2956   90 GLLDRA-EEL---------LEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPE--NAHAYCELAELYLEQ 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 465 GEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLT 544
Cdd:COG2956  158 GDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRK 237


                 ....*
gi 568920993 545 ALSLQ 549
Cdd:COG2956  238 ALELD 242
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 327-549 4.56e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 78.50  E-value: 4.56e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 327 EAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYky 406
Cdd:COG3914   34 AAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDN-- 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 407 lvknkkgspgltrrmskspvdssvlegvkelylEAAHQNgdmidpdlqtgLGVLFHLSGEFNRAIDAFNAALTVRPEDYS 486
Cdd:COG3914  112 ---------------------------------AEALFN-----------LGNLLLALGRLEEALAALRRALALNPDFAE 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568920993 487 LWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQ 549
Cdd:COG3914  148 AYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 306-525 7.01e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 74.64  E-value: 7.01e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 306 AFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTS 385
Cdd:COG3914   47 LLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALG 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 386 HQQDACEALKNWIKQNPKYkylvknkkgspgltrrmskspvdssvlegvkelylEAAHQNgdmidpdlqtgLGVLFHLSG 465
Cdd:COG3914  127 RLEEALAALRRALALNPDF-----------------------------------AEAYLN-----------LGEALRRLG 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 466 EFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNL 525
Cdd:COG3914  161 RLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 450-558 2.04e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 67.34  E-value: 2.04e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 450 DPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISC 529
Cdd:COG4235   16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAA 95

                         90       100
                 ....*....|....*....|....*....
gi 568920993 530 INLGAYREAVSNFLTALSLQRKSRNQQQV 558
Cdd:COG4235   96 FQQGDYAEAIAAWQKLLALLPADAPARLL 124
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 335-518 1.44e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 65.21  E-value: 1.44e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 335 GDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKykylvknkkgs 414
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD----------- 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 415 pgltrrmskspvdssvlegvkelyleaahqngdmiDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGAT 494
Cdd:COG4783   71 -----------------------------------EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARA 115

                        170       180
                 ....*....|....*....|....
gi 568920993 495 LANGDRSEEAVEAYTRALEIQPGF 518
Cdd:COG4783  116 YRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 452-549 6.88e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.29  E-value: 6.88e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 452 DLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCIN 531
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90
                 ....*....|....*...
gi 568920993 532 LGAYREAVSNFLTALSLQ 549
Cdd:COG4783   85 AGDYDEALALLEKALKLD 102
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 323-496 2.09e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 61.56  E-value: 2.09e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 323 ILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNP 402
Cdd:COG4235    3 IARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 403 KykylvknkkgspgltrrmskspvdssvlegvkelyleaahqngdmiDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRP 482
Cdd:COG4235   83 D----------------------------------------------NPEALYLLGLAAFQQGDYAEAIAAWQKLLALLP 116

                        170
                 ....*....|....
gi 568920993 483 EDySLWNRLGATLA 496
Cdd:COG4235  117 AD-APARLLEASIA 129
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
460-553 2.88e-11

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 60.18  E-value: 2.88e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 460 LFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAvEAYTRALEIQPGFIRSRYNLGISCINLGAYREAV 539
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|....
gi 568920993 540 SNFLTALSLQRKSR 553
Cdd:COG3063   80 AYLERALELDPSAL 93
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 450-549 3.91e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.98  E-value: 3.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 450 DPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISC 529
Cdd:COG4783   37 NPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAY 116

                         90       100
                 ....*....|....*....|
gi 568920993 530 INLGAYREAVSNFLTALSLQ 549
Cdd:COG4783  117 RALGRPDEAIAALEKALELD 136
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 431-549 8.89e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 60.74  E-value: 8.89e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 431 LEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTR 510
Cdd:COG5010   34 ANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEK 113

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 568920993 511 ALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQ 549
Cdd:COG5010  114 ALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 314-551 2.29e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 63.56  E-value: 2.29e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  314 LKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYtntSHQQDACEA 393
Cdd:TIGR02917 578 LGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAY---AVMKNYAKA 654

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  394 LKnwikqnpKYKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKELY--LEAAHQNgdmiDPDLQTGLGVLFHLSGEFNRAI 471
Cdd:TIGR02917 655 IT-------SLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAksLQKQHPK----AALGFELEGDLYLRQKDYPAAI 723

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  472 DAFNAALTVRPEDYSLWNRLGATLANGDRSeEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRK 551
Cdd:TIGR02917 724 QAYRKALKRAPSSQNAIKLHRALLASGNTA-EAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPD 802
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 308-538 3.78e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 63.18  E-value: 3.78e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  308 EEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQ 387
Cdd:TIGR02917  27 EAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKF 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  388 QDAcealknwIKQNPKYKYLvkNKKGSPGLTRRMSKSPVDSSVLEGVKELYLEAAHQNGDmiDPDLQTGLGVLFHLSGEF 467
Cdd:TIGR02917 107 QQV-------LDELPGKTLL--DDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPR--SLYAKLGLAQLALAENRF 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568920993  468 NRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREA 538
Cdd:TIGR02917 176 DEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEA 246
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 355-516 7.62e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 57.32  E-value: 7.62e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 355 AAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKykylvknkkgspgltrrmskspvdssvlegv 434
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPD------------------------------- 49

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 435 kelyleaahqngdmiDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEI 514
Cdd:COG4235   50 ---------------NADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114


                 ..
gi 568920993 515 QP 516
Cdd:COG4235  115 LP 116
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 305-525 2.16e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 60.48  E-value: 2.16e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  305 GAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNT 384
Cdd:TIGR02917 263 AHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRL 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  385 SHQQDACEALKNWIKQNP-----------KY----------KYLVKNKKGSP---------GLTRRMSKSPVdssvlEGV 434
Cdd:TIGR02917 343 GRVDEAIATLSPALGLDPddpaalsllgeAYlalgdfekaaEYLAKATELDPenaaartqlGISKLSQGDPS-----EAI 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  435 KELyLEAAHQNGDMIDPDLqtgLGVLFHL-SGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALE 513
Cdd:TIGR02917 418 ADL-ETAAQLDPELGRADL---LLILSYLrSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALS 493

                         250
                  ....*....|..
gi 568920993  514 IQPGFIRSRYNL 525
Cdd:TIGR02917 494 IEPDFFPAAANL 505
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 209-404 1.05e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.08  E-value: 1.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 209 ASELELVAPAQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQEAQNQVTVSAs 288
Cdd:COG3914   20 AAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEAL- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 289 ekGYYFHT--ENPfKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLEL 366
Cdd:COG3914   99 --ALYRRAlaLNP-DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALEL 175

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 568920993 367 QPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKY 404
Cdd:COG3914  176 DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDN 213
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
301-406 1.32e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 55.69  E-value: 1.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 301 KDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVS 380
Cdd:COG4785   71 DLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIA 150

                         90       100
                 ....*....|....*....|....*.
gi 568920993 381 YTNTSHQQDACEALKNWIKQNPKYKY 406
Cdd:COG4785  151 LYYLGRYELAIADLEKALELDPNDPE 176
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 307-404 1.79e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 53.27  E-value: 1.79e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 307 FEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSH 386
Cdd:COG4783    8 YALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGD 87

                         90
                 ....*....|....*...
gi 568920993 387 QQDACEALKNWIKQNPKY 404
Cdd:COG4783   88 YDEALALLEKALKLDPEH 105
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 457-554 3.54e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 55.12  E-value: 3.54e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 457 LGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYR 536
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLD 93

                         90
                 ....*....|....*...
gi 568920993 537 EAVSNFLTALSLQRKSRN 554
Cdd:COG2956   94 RAEELLEKLLELDPDDAE 111
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 314-515 5.47e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 54.35  E-value: 5.47e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 314 LKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEA 393
Cdd:COG2956  121 EQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAA 200

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 394 LKNWIKQNPKYkylvknkkgspgltrrmskspvdSSVLEGVKELYLEAahqngdmidpdlqtglgvlfhlsGEFNRAIDA 473
Cdd:COG2956  201 LERALEQDPDY-----------------------LPALPRLAELYEKL-----------------------GDPEEALEL 234

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 568920993 474 FNAALTVRPEDySLWNRLGATLANGDRSEEAVEAYTRALEIQ 515
Cdd:COG2956  235 LRKALELDPSD-DLLLALADLLERKEGLEAALALLERQLRRH 275
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 469-549 7.66e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.55  E-value: 7.66e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 469 RAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSL 548
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                 .
gi 568920993 549 Q 549
Cdd:COG4235   81 D 81
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 436-552 8.32e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 53.96  E-value: 8.32e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 436 ELYLEAAHQNGDmiDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQ 515
Cdd:COG2956   29 DLLEEALELDPE--TVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELD 106

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 568920993 516 PGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKS 552
Cdd:COG2956  107 PDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN 143
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 310-548 1.47e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.70  E-value: 1.47e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  310 GLKRLK--EGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQ 387
Cdd:TIGR02917 164 GLAQLAlaENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEF 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  388 QDA---CEALKNWIKQNPKYKYL-----VKNKK---GSPGLTRRMSKSP--VDSSVLEGVKELYL---EAAHQNGDMI-- 449
Cdd:TIGR02917 244 EEAekhADALLKKAPNSPLAHYLkalvdFQKKNyedARETLQDALKSAPeyLPALLLAGASEYQLgnlEQAYQYLNQIlk 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  450 -DPDLQTG---LGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGAT-LANGDrSEEAVEAYTRALEIQPGFIRSRYN 524
Cdd:TIGR02917 324 yAPNSHQArrlLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAyLALGD-FEKAAEYLAKATELDPENAAARTQ 402

                         250       260
                  ....*....|....*....|....
gi 568920993  525 LGISCINLGAYREAVSNFLTALSL 548
Cdd:TIGR02917 403 LGISKLSQGDPSEAIADLETAAQL 426
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 314-404 1.58e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.58  E-value: 1.58e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 314 LKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEA 393
Cdd:COG4783   49 LQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAA 128

                         90
                 ....*....|.
gi 568920993 394 LKNWIKQNPKY 404
Cdd:COG4783  129 LEKALELDPDD 139
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
450-516 2.44e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.84  E-value: 2.44e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568920993 450 DPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPED-YSLWNRlGATLANGDRSEEAVEAYTRALEIQP 516
Cdd:COG4785  106 LAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYaYAYLNR-GIALYYLGRYELAIADLEKALELDP 172
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
467-603 5.23e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 51.07  E-value: 5.23e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 467 FNRAIDAFNAALTvRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTAL 546
Cdd:COG4785   56 AALAAERIDRALA-LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL 134

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 568920993 547 SLQRKsrnqqqvphpaiSGNIWAALRIALSLMDQPELFQAanlgDLDVLLRAFNLDP 603
Cdd:COG4785  135 ELDPD------------YAYAYLNRGIALYYLGRYELAIA----DLEKALELDPNDP 175
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 431-603 5.84e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 52.69  E-value: 5.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 431 LEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTR 510
Cdd:COG3914   24 AELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRR 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 511 ALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQrksrnqqqvphpaiSGNIWAALRIALSLMDQpELFQAAnlg 590
Cdd:COG3914  104 ALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALN--------------PDFAEAYLNLGEALRRL-GRLEEA--- 165

                        170
                 ....*....|...
gi 568920993 591 dLDVLLRAFNLDP 603
Cdd:COG3914  166 -IAALRRALELDP 177
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 297-403 1.41e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.69  E-value: 1.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 297 ENPfKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMA 376
Cdd:COG4235   12 ANP-NDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYL 90

                         90       100
                 ....*....|....*....|....*..
gi 568920993 377 LAVSYTNTSHQQDACEALKNWIKQNPK 403
Cdd:COG4235   91 LGLAAFQQGDYAEAIAAWQKLLALLPA 117
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 431-516 3.07e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.26  E-value: 3.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 431 LEGVKELYLEAAHQNGDmiDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTR 510
Cdd:COG5010   70 FEESLALLEQALQLDPN--NPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147


                 ....*.
gi 568920993 511 ALEIQP 516
Cdd:COG5010  148 ALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
314-403 6.25e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.78  E-value: 6.25e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 314 LKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIvALQRCLELQPNNLKALMALAVSYTNTSHQQDACEA 393
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAY 81

                         90
                 ....*....|
gi 568920993 394 LKNWIKQNPK 403
Cdd:COG3063   82 LERALELDPS 91
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 314-402 6.98e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 46.49  E-value: 6.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 314 LKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEA 393
Cdd:COG5010   65 NKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAA 144


                 ....*....
gi 568920993 394 LKNWIKQNP 402
Cdd:COG5010  145 LQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 332-516 2.30e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 2.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  332 QDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYL---- 407
Cdd:TIGR02917 460 KQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAilal 539

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  408 --VKNKKGSPgltrrmskspvdssvlEGVKELYLEAAHQNGDMIDPDLQtgLGVLFHLSGEFNRAIDAFNAALTVRPEDY 485
Cdd:TIGR02917 540 agLYLRTGNE----------------EEAVAWLEKAAELNPQEIEPALA--LAQYYLGKGQLKKALAILNEAADAAPDSP 601

                         170       180       190
                  ....*....|....*....|....*....|..
gi 568920993  486 SLWNRLGAT-LANGDrSEEAVEAYTRALEIQP 516
Cdd:TIGR02917 602 EAWLMLGRAqLAAGD-LNKAVSSFKKLLALQP 632
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 325-539 4.14e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 45.70  E-value: 4.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 325 FMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNL-KALMAL--------AVSYTNTshqqdACEALK 395
Cdd:cd24142   22 FLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyEKYLYLgqlsggeeALQYYEK-----GIEILE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 396 NWIKQNPKYKYLvkNKKGSPGLTRRMskspvdSSVLEGVKELYL-------------EAAHQNGDMIDPD----LQTgLG 458
Cdd:cd24142   97 EELQALQAASAE--AEEEAEELKRKL------SSALCALAEIYMtdlcdepdaeqrcEELITKALELDPTnpeaLQT-LA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 459 VLfHLS-GEFNRAIDAFNAAltvrpedYSLWNRLGATLANGDRSEEAVEAYTRALEiqpgfirSRYNLGISCINLGAYRE 537
Cdd:cd24142  168 SL-RISqQRPDEAKEALRRS-------LELWKDLKEEDEEEAEEDEAEEEDVPSYE-------FRISLAKLLIELEMYEE 232


                 ..
gi 568920993 538 AV 539
Cdd:cd24142  233 AL 234
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 310-552 6.37e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 6.37e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  310 GLKRLKEGDLPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQD 389
Cdd:TIGR02917 370 GEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDK 449

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  390 ACEALKNWIKQNPKyKYLVKNKKGSPGLTRR-MSKSpvdssvlegvkELYLEAAHQngdmIDPDLQTGLGVLFHLSGEFN 468
Cdd:TIGR02917 450 ALAAAKKLEKKQPD-NASLHNLLGAIYLGKGdLAKA-----------REAFEKALS----IEPDFFPAAANLARIDIQEG 513

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  469 R---AIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTA 545
Cdd:TIGR02917 514 NpddAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEA 593


                  ....*..
gi 568920993  546 LSLQRKS 552
Cdd:TIGR02917 594 ADAAPDS 600
TPR_12 pfam13424
Tetratricopeptide repeat;
486-551 8.52e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 8.52e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568920993  486 SLWNRLGATLANGDRSEEAVEAYTRALEIQ--------PGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRK 551
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 457-559 1.66e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 44.59  E-value: 1.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  457 LGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRsEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYR 536
Cdd:TIGR00990 133 KGNKAYRNKDFNKAIKLYSKAIECKPDPVYYSNRAACHNALGDW-EKVVEDTTAALELDPDYSKALNRRANAYDGLGKYA 211

                          90       100
                  ....*....|....*....|...
gi 568920993  537 EAVSNFlTALSLQRKSRNQQQVP 559
Cdd:TIGR00990 212 DALLDL-TASCIIDGFRNEQSAQ 233
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
502-603 7.03e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 7.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 502 EEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSnFLTALSLQrksrnqqqvphpaiSGNIWAALRIALSLMDQP 581
Cdd:COG3063    9 EEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLD--------------PNNAEALLNLAELLLELG 73

                         90       100
                 ....*....|....*....|..
gi 568920993 582 ELFQAanlgdLDVLLRAFNLDP 603
Cdd:COG3063   74 DYDEA-----LAYLERALELDP 90
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 464-542 8.90e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.20  E-value: 8.90e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 464 SGEFNRAIDAFNAALTVRPEDYSLWN---RLGATLANGDRSEEAVEAYTRALEIQPGFIR---SRYNLGISCINLGAYRE 537
Cdd:COG1729    6 AGDYDEAIAAFKAFLKRYPNSPLAPDalyWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDK 85


                 ....*
gi 568920993 538 AVSNF 542
Cdd:COG1729   86 ARATL 90
TPR_1 pfam00515
Tetratricopeptide repeat;
488-518 1.14e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 36.63  E-value: 1.14e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 568920993  488 WNRLGATLANGDRSEEAVEAYTRALEIQPGF 518
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 314-412 1.47e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.82  E-value: 1.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 314 LKEGDLPVTILFMEAAILQDPGD---AEAWQFLGITQAENENEQAAIVALQRCLELQPNNLK---ALMALAVSYTNTSHQ 387
Cdd:COG1729    4 LKAGDYDEAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDY 83

                         90       100
                 ....*....|....*....|....*
gi 568920993 388 QDACEALKNWIKQNPKYKYLVKNKK 412
Cdd:COG1729   84 DKARATLEELIKKYPDSEAAKEARA 108
PRK11189 PRK11189
lipoprotein NlpI; Provisional
 457-506 1.81e-03

lipoprotein NlpI; Provisional


Pssm-ID: 236875 [Multi-domain]  Cd Length: 296  Bit Score: 40.64  E-value: 1.81e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 568920993 457 LGVLFHLSGEFNRAIDAFNAALTVRPE-DYSLWNRlGATLANGDRSEEAVE 506
Cdd:PRK11189 104 LGIYLTQAGNFDAAYEAFDSVLELDPTyNYAYLNR-GIALYYGGRYELAQD 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 327-410 3.14e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.79  E-value: 3.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 327 EAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKY 406
Cdd:COG5010   44 AAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPN 123


                 ....
gi 568920993 407 LVKN 410
Cdd:COG5010  124 AYSN 127
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 332-504 3.40e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 3.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  332 QDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLkALMALAVSYTNTSHQQDACEALKNWIKQNPK-------- 403
Cdd:TIGR02917 698 QHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQ-NAIKLHRALLASGNTAEAVKTLEAWLKTHPNdavlrtal 776

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993  404 ---YKYLVKNKKGSPGLTRRMSKSPVDSSVLEGVKELYL-----------EAAHQNGDMIDPDLQTgLGVLFHLSGEFNR 469
Cdd:TIGR02917 777 aelYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLelkdpraleyaERALKLAPNIPAILDT-LGWLLVEKGEADR 855

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 568920993  470 AIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEA 504
Cdd:TIGR02917 856 ALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEA 890
TPR_1 pfam00515
Tetratricopeptide repeat;
337-370 5.85e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 5.85e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 568920993  337 AEAWQFLGITQAENENEQAAIVALQRCLELQPNN 370
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 483-603 7.18e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.09  E-value: 7.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568920993 483 EDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKsrnqqqvphpa 562
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPD----------- 70

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 568920993 563 isgNIWAALRIALSLMDQPELFQAanlgdLDVLLRAFNLDP 603
Cdd:COG4783   71 ---EPEARLNLGLALLKAGDYDEA-----LALLEKALKLDP 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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