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Conserved domains on  [gi|568972033|ref|XP_006532471|]
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microtubule-associated protein tau isoform X19 [Mus musculus]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 264-293 9.54e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 56.27  E-value: 9.54e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 568972033  264 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 293
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 295-325 6.36e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.95  E-value: 6.36e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 568972033  295 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 325
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 241-262 2.28e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 46.64  E-value: 2.28e-07
                          10        20
                  ....*....|....*....|..
gi 568972033  241 DLKNVRSKIGSTENLKHQPGGG 262
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 27-260 1.73e-05

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.09  E-value: 1.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033   27 DMDHGLKESPPQPPADDGAEEPGSETSDAKSTPTAEDVTAPLVDERAPDKQAAAQPHTEIPEGITAEEAGIGDTPnQEDQ 106
Cdd:PHA03307  177 SSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGP-ENEC 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033  107 AAGHVTQARVASKDRTGNdEKKAKGADGKTGAKIATPRGAASPAQKGTSNAtriPAKTTPSPKTPPGSGEPPKSGERSGY 186
Cdd:PHA03307  256 PLPRPAPITLPTRIWEAS-GWNGPSSRPGPASSSSSPRERSPSPSPSSPGS---GPAPSSPRASSSSSSSRESSSSSTSS 331

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568972033  187 SSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMPDLKNVRSKIGSTENLKHQPG 260
Cdd:PHA03307  332 SSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATG 405
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 264-293 9.54e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 56.27  E-value: 9.54e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 568972033  264 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 293
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 295-325 6.36e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.95  E-value: 6.36e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 568972033  295 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 325
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 241-262 2.28e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 46.64  E-value: 2.28e-07
                          10        20
                  ....*....|....*....|..
gi 568972033  241 DLKNVRSKIGSTENLKHQPGGG 262
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 27-260 1.73e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.09  E-value: 1.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033   27 DMDHGLKESPPQPPADDGAEEPGSETSDAKSTPTAEDVTAPLVDERAPDKQAAAQPHTEIPEGITAEEAGIGDTPnQEDQ 106
Cdd:PHA03307  177 SSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGP-ENEC 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033  107 AAGHVTQARVASKDRTGNdEKKAKGADGKTGAKIATPRGAASPAQKGTSNAtriPAKTTPSPKTPPGSGEPPKSGERSGY 186
Cdd:PHA03307  256 PLPRPAPITLPTRIWEAS-GWNGPSSRPGPASSSSSPRERSPSPSPSSPGS---GPAPSSPRASSSSSSSRESSSSSTSS 331

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568972033  187 SSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMPDLKNVRSKIGSTENLKHQPG 260
Cdd:PHA03307  332 SSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATG 405
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 264-293 9.54e-11

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 56.27  E-value: 9.54e-11
                          10        20        30
                  ....*....|....*....|....*....|
gi 568972033  264 VQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 293
Cdd:pfam00418   1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 295-325 6.36e-10

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.95  E-value: 6.36e-10
                          10        20        30
                  ....*....|....*....|....*....|.
gi 568972033  295 VEVKSEKLDFKdRVQSKIGSLDNITHVPGGG 325
Cdd:pfam00418   1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 241-262 2.28e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 46.64  E-value: 2.28e-07
                          10        20
                  ....*....|....*....|..
gi 568972033  241 DLKNVRSKIGSTENLKHQPGGG 262
Cdd:pfam00418   9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 27-260 1.73e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 47.09  E-value: 1.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033   27 DMDHGLKESPPQPPADDGAEEPGSETSDAKSTPTAEDVTAPLVDERAPDKQAAAQPHTEIPEGITAEEAGIGDTPnQEDQ 106
Cdd:PHA03307  177 SSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGP-ENEC 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033  107 AAGHVTQARVASKDRTGNdEKKAKGADGKTGAKIATPRGAASPAQKGTSNAtriPAKTTPSPKTPPGSGEPPKSGERSGY 186
Cdd:PHA03307  256 PLPRPAPITLPTRIWEAS-GWNGPSSRPGPASSSSSPRERSPSPSPSSPGS---GPAPSSPRASSSSSSSRESSSSSTSS 331

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568972033  187 SSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMPDLKNVRSKIGSTENLKHQPG 260
Cdd:PHA03307  332 SSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATG 405
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 40-238 1.26e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.39  E-value: 1.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033   40 PADDGAEEPGSETSDAKSTPTAEDVTAPLVDERAPDkqaaaqPHTEIPEGITAEEAGIGDTPNQEDQAAGHVTQARVASK 119
Cdd:PHA03307   27 TPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAAC------DRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASP 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033  120 DRTGNDEKKAKGADGKTGAKIATPRGAASPAQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGERSGYSSPGSP---GTPG 196
Cdd:PHA03307  101 AREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAAlplSSPE 180

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 568972033  197 SRSRTPS--LPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVP 238
Cdd:PHA03307  181 ETARAPSspPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAP 224
PHA03247 PHA03247
large tegument protein UL36; Provisional
 32-240 2.59e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 2.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033   32 LKESPPQPPADDGAEEPGSETSDAKSTPTAEDVTAP---LVDERAPDKQAAAQPHTEIPEGITAEEAGIGDTPNQEDQAA 108
Cdd:PHA03247 2698 LADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPalpAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA 2777

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033  109 G---HVTQARVASKdrtgndekkAKGADGKTGAKIATPRGAASPAQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGERSG 185
Cdd:PHA03247 2778 GpprRLTRPAVASL---------SESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPP 2848

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568972033  186 YSSPGSPGTPGS--RSRTPSLPTPPT----REPKKVAVVRTPPKSPSASKSRLQTAPVPMP 240
Cdd:PHA03247 2849 SLPLGGSVAPGGdvRRRPPSRSPAAKpaapARPPVRRLARPAVSRSTESFALPPDQPERPP 2909
PHA03247 PHA03247
large tegument protein UL36; Provisional
 37-240 2.70e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.39  E-value: 2.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033   37 PQPPADDGAEEPGSETSDAKSTPTAEDVTAPLVDERAPDKQAAAQPHTEIPEgiTAEEAGIGDTPNQEDQAAGHVTQARV 116
Cdd:PHA03247 2769 PAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP--AASPAGPLPPPTSAQPTAPPPPPGPP 2846

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033  117 ASKDRTGNdeKKAKGADGKTgakiatpRGAASPAQKGTSNATRIPAKTTPSPKTPPGS---GEPPKSGERSGYSSPGSPG 193
Cdd:PHA03247 2847 PPSLPLGG--SVAPGGDVRR-------RPPSRSPAAKPAAPARPPVRRLARPAVSRSTesfALPPDQPERPPQPQAPPPP 2917

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 568972033  194 TPGSRSRTPSLPTPPTrepkkvavvRTPPKSPSASKSRLQTAPVPMP 240
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPP---------PPPPRPQPPLAPTTDPAGAGEP 2955
PHA03247 PHA03247
large tegument protein UL36; Provisional
 26-240 7.34e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 7.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033   26 GDMDHGLKESPPQP-PADDGAEEPGSETSDAKSTPTAEDVTAPlVDERAPDKQAAAQPHTEIPEGIT--AEEAGIGDTPN 102
Cdd:PHA03247 2603 DDRGDPRGPAPPSPlPPDTHAPDPPPPSPSPAANEPDPHPPPT-VPPPERPRDDPAPGRVSRPRRARrlGRAAQASSPPQ 2681

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033  103 QEDQAAGHVTQARVASKDRTGNDEKKAKGADGKTGAKIATPRGAAspAQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGE 182
Cdd:PHA03247 2682 RPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPA--AARQASPALPAAPAPPAVPAGPATPGGPARPAR 2759

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568972033  183 RSGYSSPGSPGTPGSRSRTPSLPTPPtrePKKVAVVRTPPKSPSASKSRLQTAPVPMP 240
Cdd:PHA03247 2760 PPTTAGPPAPAPPAAPAAGPPRRLTR---PAVASLSESRESLPSPWDPADPPAAVLAP 2814
valS PRK14900
valyl-tRNA synthetase; Provisional
 49-171 1.06e-03

valyl-tRNA synthetase; Provisional


Pssm-ID: 237855 [Multi-domain]  Cd Length: 1052  Bit Score: 41.52  E-value: 1.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033   49 GSE-TSDAKSTPTAEDVTAPLVDERAPDkqAAAQPHTEIPEGITAEEAGIGDTPNQEDQAAGHVTQARVASKDRTGNDEK 127
Cdd:PRK14900  905 GSEaNSARRDTMEIQNEQKPTQDGPAAE--AQPAQENTVVESAEKAVAAVSEAAQQAATAVASGIEKVAEAVRKTVRRSV 982

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 568972033  128 KAKGADGKTGAKIATPRGAASPAQKGTSNATRIPAKTTPSPKTP 171
Cdd:PRK14900  983 KKAAATRAAMKKKVAKKAPAKKAAAKKAAAKKAAAKKKVAKKAP 1026
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 41-203 1.09e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 41.12  E-value: 1.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033  41 ADDGAEEPGSETSDAKSTPTAEDVTAPlVDERAPDK-----QAAAQPHTEIPEGITAEEAGIGDTPNQEDQAAGHVTQAR 115
Cdd:PRK13108 291 VVDEALEREPAELAAAAVASAASAVGP-VGPGEPNQpddvaEAVKAEVAEVTDEVAAESVVQVADRDGESTPAVEETSEA 369

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033 116 VASKDRTGNDEKKAKGAD--GKTGAKIATPRGAASPAQKGTSNATRIPAKTTPSpktpPGSGEPPKSGERSGYSSPGSPG 193
Cdd:PRK13108 370 DIEREQPGDLAGQAPAAHqvDAEAASAAPEEPAALASEAHDETEPEVPEKAAPI----PDPAKPDELAVAGPGDDPAEPD 445

                        170
                 ....*....|
gi 568972033 194 TPGSRSRTPS 203
Cdd:PRK13108 446 GIRRQDDFSS 455
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 34-217 1.11e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 1.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033  34 ESPPQPPADDGAEEPGSETSDAKSTPTAEDVTAPLVDERAPDKQAAAQPHTEIPEGITAEEAGIGD----TPNQEDQAAG 109
Cdd:PRK07764 610 EEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGaapaAPPPAPAPAA 689

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033 110 HVTQARVASKD-RTGNDEKKAKGADGKTGAKIATPRGAASPAQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGERSGYSS 188
Cdd:PRK07764 690 PAAPAGAAPAQpAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAA 769

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 568972033 189 PGSPGTPGSRSR--------TPSLPTPPTREPKKVAV 217
Cdd:PRK07764 770 PAAAPPPSPPSEeeemaeddAPSMDDEDRRDAEEVAM 806
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 121-240 2.66e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.08  E-value: 2.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033 121 RTGNDEKKAKGADGKTGAKIATPRGAASPAQKGTSNA--TRIPAKTTPSPKTPPGSGEPPKSGeRSGYSSPGSPGTPGSR 198
Cdd:PRK14951 365 KPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPapAAAPAAAASAPAAPPAAAPPAPVA-APAAAAPAAAPAAAPA 443

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 568972033 199 SRT--PSLPTPPTREPKKVAVVRTPPKSPSASKSRLQTAPVPMP 240
Cdd:PRK14951 444 AVAlaPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAAR 487
PHA03247 PHA03247
large tegument protein UL36; Provisional
 34-234 6.41e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.15  E-value: 6.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033   34 ESPPQPPADDGAEEPGSETsdakstptAEDVTAPLvderapdkqaaAQPHTEIPEGITAEEAGIGDTPNQ-EDQAAGhvt 112
Cdd:PHA03247  314 DPPPPAPAGDAEEEDDEDG--------AMEVVSPL-----------PRPRQHYPLGFPKRRRPTWTPPSSlEDLSAG--- 371

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033  113 qarvaskdrtgndEKKAKGADGKTGAKIATPRGAASPAQKGTSNATRIPAKTTPSPKTPPGSGEPPKSGERSGYSSPGSP 192
Cdd:PHA03247  372 -------------RHHPKRASLPTRKRRSARHAATPFARGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSA 438

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 568972033  193 GTPGSRSRTPslptPPTREPKKVAVVRTPPKSPSASKSRLQT 234
Cdd:PHA03247  439 EPGSDDGPAP----PPERQPPAPATEPAPDDPDDATRKALDA 476
PHA03378 PHA03378
EBNA-3B; Provisional
 143-240 6.69e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 38.89  E-value: 6.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033 143 PRGAASPAQKGTSNATRIPakttpSPKTPPGSGEPPKSGERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKvAVVRTPP 222
Cdd:PHA03378 707 PAAPPGRAQRPAAATGRAR-----PPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGA-PTPQPPP 780

                         90
                 ....*....|....*...
gi 568972033 223 KSPSASKSRLQTAPVPMP 240
Cdd:PHA03378 781 QAPPAPQQRPRGAPTPQP 798
PHA02682 PHA02682
ORF080 virion core protein; Provisional
 143-243 7.83e-03

ORF080 virion core protein; Provisional


Pssm-ID: 177464 [Multi-domain]  Cd Length: 280  Bit Score: 37.92  E-value: 7.83e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033 143 PRGAASPAQKGTSNATRIPAKT--TPSPKTPPGSGE---PPKSGERSGYSSPGSPGTPGSRSRTPSLPTP---PTREPKK 214
Cdd:PHA02682  87 ACAAPAPACPACAPAAPAPAVTcpAPAPACPPATAPtcpPPAVCPAPARPAPACPPSTRQCPPAPPLPTPkpaPAAKPIF 166

                         90       100
                 ....*....|....*....|....*....
gi 568972033 215 VAVVRTPPKSPSASKSRLQTAPVPMPDLK 243
Cdd:PHA02682 167 LHNQLPPPDYPAASCPTIETAPAASPVLE 195
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 142-255 8.88e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 38.25  E-value: 8.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568972033 142 TPRGAASPAQkgTSNATRIPAKTTPSPKTPPGSGEPpksgersgysSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP 221
Cdd:PRK14950 361 VPVPAPQPAK--PTAAAPSPVRPTPAPSTRPKAAAA----------ANIPPKEPVRETATPPPVPPRPVAPPVPHTPESA 428

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 568972033 222 PKSPSASkSRLQTAPV---PMPDLKNVRSKIGSTENL 255
Cdd:PRK14950 429 PKLTRAA-IPVDEKPKytpPAPPKEEEKALIADGDVL 464
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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