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Conserved domains on  [gi|569005368|ref|XP_006526557|]
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zinc finger protein 236 isoform X3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
653-1058 8.37e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 8.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  653 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHVRTHTGLKSFKCLICNG-AFTTGGS 729
Cdd:COG5048    28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  730 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQEaSSMDDDSTVDQQSMHVAAPMPVEIESAELQ 809
Cdd:COG5048   108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNS-SSVNTPQSNSLHPPLPANSLSKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  810 QTPETVAADPESILELGPQHvvgtedaalgqQLADQPLEADEDGFTASQAPLPGHMDQFEEQGTPQPSfesagLPQGFTV 889
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLS-----------SSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQ-----SPSSLSS 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  890 TDTYSQQTSFPPVQQLQDSSTLESQALSTSFHQQNLLQVPNSDAINvatrllPESSQEDlDLQTQGPQFLEDSEDQSRRS 969
Cdd:COG5048   251 SDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCN------ISFSRSS-PLTRHLRSVNHSGESLKPFS 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  970 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKS-------HEKTHTGVKAFSC--SICNASFTTNGS 1040
Cdd:COG5048   324 CPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETlsNSCIRNFKRDSN 403

                         410
                  ....*....|....*...
gi 569005368 1041 LTRHMATHMSMKPYKCPF 1058
Cdd:COG5048   404 LSLHIITHLSFRPYNCKN 421
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
197-550 4.14e-08

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.78  E-value: 4.14e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  197 FPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 274
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  275 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPPNSTTSaeTAHVITATIFQTLPLQQVEAQVSSVS 348
Cdd:COG5048   104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNN--SSSVNTPQSNSLHPPLPANSLSKDPS 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  349 SEQSSQAVSDVIQQLLELSEPGPVEAQQSPQSgrQLSVTVGINQDILQQALENSGLSslpvaaPPSDCSHAQTATVSTQS 428
Cdd:COG5048   182 SNLSLLISSNVSTSIPSSSENSPLSSSYSIPS--SSSDQNLENSSSSLPLTTNSQLS------PKSLLSQSPSSLSSSDS 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  429 PHASSVSAEQADPMDAEQEKgqespektdkkekkllkkkSPFLPGSIREENGVRWHVCPYCTKEFRKPSDLVRHIRIHTH 508
Cdd:COG5048   254 SSSASESPRSSLPTASSQSS-------------------SPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNH 314

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 569005368  509 E----KPFKCP--QCFRAFAVKSTLTAHIKTHTGIKAFKCQY--CMKSFS 550
Cdd:COG5048   315 SgeslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFS 364
FhaB super family cl27105
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1340-1599 1.12e-07

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


The actual alignment was detected with superfamily member COG3210:

Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.08  E-value: 1.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1340 ASVSAGGDLTVSL--TDGSL-------ATLEGIQLQLAANLVGPNVQISGIDASSINNITLQIDPSILQQTLqQGSLLAQ 1410
Cdd:COG3210   802 GTITAAGTTAINVtgSGGTItintattGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAAT-AASITVG 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1411 PITGESSTASQNSSLQTSDSTVPASVVIQPLSGLSLQPTVTSANLTIGPLSEQDSVLTTSSSGSQDLSQVMTSQGLVSTS 1490
Cdd:COG3210   881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1491 TGPHEITLTINNSSLSQVLAQAAGPTASSSSGSPQEITLTISELNPSSGSLPSTAPMSPSAISAQNLVMSSSGVGADASV 1570
Cdd:COG3210   961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATA 1040

                         250       260
                  ....*....|....*....|....*....
gi 569005368 1571 TLTLADTQGVLSGGLDTVTLNITSQVTDV 1599
Cdd:COG3210  1041 GGQNGVGVNASGISGGNAAALTASGTAGT 1069
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
937-1317 2.95e-06

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.01  E-value: 2.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  937 ATRLLPESSQEDLDLQTQGPQFLEDSEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKSH 1016
Cdd:COG5048     1 ATLTSSQSSSSNNSVLSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1017 ---EKTHTGVKAFSCSICNASFTTNGSLTRHMATHMSMKPYKCPFCEEGfrtavhcrkHMKRHQAVSSAAAAAAETEGGD 1093
Cdd:COG5048    81 rhlRTHHNNPSDLNSKSLPLSNSKASSSSLSSSSSNSNDNNLLSSHSLP---------PSSRDPQLPDLLSISNLRNNPL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1094 TCVEEDEENSDRSASRKPRPEVITFTEEETAQLAKIqPQESATVSEKV------LVQSAAEKDRISEMKDKQAELEAEPK 1167
Cdd:COG5048   152 PGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLL-ISSNVSTSIPSssenspLSSSYSIPSSSSDQNLENSSSSLPLT 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1168 HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCH-VCSNAFSTKGSLKVHMR 1246
Cdd:COG5048   231 TNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSkQCNISFSRSSPLTRHLR 310

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 569005368 1247 --LHTG--AKPFKCPH--CELRFRTSGRRKTHMQFHYKSDPKKarKPVTRSSSESLQSVNLLNSSSTDPNVFIMNNS 1317
Cdd:COG5048   311 svNHSGesLKPFSCPYslCGKLFSRNDALKRHILLHTSISPAK--EKLLNSSSKFSPLLNNEPPQSLQQYKDLKNDK 385
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1696-1720 1.34e-05

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.51  E-value: 1.34e-05
                           10        20
                   ....*....|....*....|....*
gi 569005368  1696 LERHSRIHTGERPFHCTLCDKAFNQ 1720
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
554-579 2.47e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.66  E-value: 2.47e-04
                           10        20
                   ....*....|....*....|....*.
gi 569005368   554 SLKVHIRLHTGVRPFACPHCDKKFRT 579
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
30-234 1.11e-03

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.53  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368   30 DDDCPIPNFHKCEICLLSFPKESQFQRHMREHEQNDKPHRCDQCPQTFNVEFNLTLHKCTHNAEDP-----VCPV--CNK 102
Cdd:COG5048   252 DSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNHSGEslkpfSCPYslCGK 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  103 KFSRVASLKAHIMLHEKEENLICSECGDEFTLHSqlAIHMEEHRQELANTRAHTckacKKEFETSPELKEhmkTHCKVRA 182
Cdd:COG5048   332 LFSRNDALKRHILLHTSISPAKEKLLNSSSKFSP--LLNNEPPQSLQQYKDLKN----DKKSETLSNSCI---RNFKRDS 402

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 569005368  183 SGTRSYNRNIDRSSFPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGK 234
Cdd:COG5048   403 NLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1723-1748 1.66e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 1.66e-03
                           10        20
                   ....*....|....*....|....*.
gi 569005368  1723 ALQVHLKKHTGERPYRCDYCVMGFTQ 1748
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like super family cl41227
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1618-1666 2.82e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


The actual alignment was detected with superfamily member cd20908:

Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.31  E-value: 2.82e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 569005368 1618 CLDCDRAFSSAAVLMHHSKEVHGKerihgCRVCRKAFKRATHLKEHMLT 1666
Cdd:cd20908     4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
653-1058 8.37e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 8.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  653 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHVRTHTGLKSFKCLICNG-AFTTGGS 729
Cdd:COG5048    28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  730 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQEaSSMDDDSTVDQQSMHVAAPMPVEIESAELQ 809
Cdd:COG5048   108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNS-SSVNTPQSNSLHPPLPANSLSKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  810 QTPETVAADPESILELGPQHvvgtedaalgqQLADQPLEADEDGFTASQAPLPGHMDQFEEQGTPQPSfesagLPQGFTV 889
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLS-----------SSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQ-----SPSSLSS 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  890 TDTYSQQTSFPPVQQLQDSSTLESQALSTSFHQQNLLQVPNSDAINvatrllPESSQEDlDLQTQGPQFLEDSEDQSRRS 969
Cdd:COG5048   251 SDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCN------ISFSRSS-PLTRHLRSVNHSGESLKPFS 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  970 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKS-------HEKTHTGVKAFSC--SICNASFTTNGS 1040
Cdd:COG5048   324 CPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETlsNSCIRNFKRDSN 403

                         410
                  ....*....|....*...
gi 569005368 1041 LTRHMATHMSMKPYKCPF 1058
Cdd:COG5048   404 LSLHIITHLSFRPYNCKN 421
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
197-550 4.14e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.78  E-value: 4.14e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  197 FPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 274
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  275 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPPNSTTSaeTAHVITATIFQTLPLQQVEAQVSSVS 348
Cdd:COG5048   104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNN--SSSVNTPQSNSLHPPLPANSLSKDPS 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  349 SEQSSQAVSDVIQQLLELSEPGPVEAQQSPQSgrQLSVTVGINQDILQQALENSGLSslpvaaPPSDCSHAQTATVSTQS 428
Cdd:COG5048   182 SNLSLLISSNVSTSIPSSSENSPLSSSYSIPS--SSSDQNLENSSSSLPLTTNSQLS------PKSLLSQSPSSLSSSDS 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  429 PHASSVSAEQADPMDAEQEKgqespektdkkekkllkkkSPFLPGSIREENGVRWHVCPYCTKEFRKPSDLVRHIRIHTH 508
Cdd:COG5048   254 SSSASESPRSSLPTASSQSS-------------------SPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNH 314

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 569005368  509 E----KPFKCP--QCFRAFAVKSTLTAHIKTHTGIKAFKCQY--CMKSFS 550
Cdd:COG5048   315 SgeslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFS 364
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1340-1599 1.12e-07

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.08  E-value: 1.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1340 ASVSAGGDLTVSL--TDGSL-------ATLEGIQLQLAANLVGPNVQISGIDASSINNITLQIDPSILQQTLqQGSLLAQ 1410
Cdd:COG3210   802 GTITAAGTTAINVtgSGGTItintattGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAAT-AASITVG 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1411 PITGESSTASQNSSLQTSDSTVPASVVIQPLSGLSLQPTVTSANLTIGPLSEQDSVLTTSSSGSQDLSQVMTSQGLVSTS 1490
Cdd:COG3210   881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1491 TGPHEITLTINNSSLSQVLAQAAGPTASSSSGSPQEITLTISELNPSSGSLPSTAPMSPSAISAQNLVMSSSGVGADASV 1570
Cdd:COG3210   961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATA 1040

                         250       260
                  ....*....|....*....|....*....
gi 569005368 1571 TLTLADTQGVLSGGLDTVTLNITSQVTDV 1599
Cdd:COG3210  1041 GGQNGVGVNASGISGGNAAALTASGTAGT 1069
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
937-1317 2.95e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.01  E-value: 2.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  937 ATRLLPESSQEDLDLQTQGPQFLEDSEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKSH 1016
Cdd:COG5048     1 ATLTSSQSSSSNNSVLSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1017 ---EKTHTGVKAFSCSICNASFTTNGSLTRHMATHMSMKPYKCPFCEEGfrtavhcrkHMKRHQAVSSAAAAAAETEGGD 1093
Cdd:COG5048    81 rhlRTHHNNPSDLNSKSLPLSNSKASSSSLSSSSSNSNDNNLLSSHSLP---------PSSRDPQLPDLLSISNLRNNPL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1094 TCVEEDEENSDRSASRKPRPEVITFTEEETAQLAKIqPQESATVSEKV------LVQSAAEKDRISEMKDKQAELEAEPK 1167
Cdd:COG5048   152 PGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLL-ISSNVSTSIPSssenspLSSSYSIPSSSSDQNLENSSSSLPLT 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1168 HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCH-VCSNAFSTKGSLKVHMR 1246
Cdd:COG5048   231 TNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSkQCNISFSRSSPLTRHLR 310

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 569005368 1247 --LHTG--AKPFKCPH--CELRFRTSGRRKTHMQFHYKSDPKKarKPVTRSSSESLQSVNLLNSSSTDPNVFIMNNS 1317
Cdd:COG5048   311 svNHSGesLKPFSCPYslCGKLFSRNDALKRHILLHTSISPAK--EKLLNSSSKFSPLLNNEPPQSLQQYKDLKNDK 385
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1184-1208 3.31e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.05  E-value: 3.31e-06
                           10        20
                   ....*....|....*....|....*
gi 569005368  1184 DLVRHVRIHTGEKPYKCDECGKSFT 1208
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
984-1009 7.61e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 7.61e-06
                           10        20
                   ....*....|....*....|....*.
gi 569005368   984 HLKQHVRSHTGEKPYKCKLCGRAFVS 1009
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
214-238 8.23e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 8.23e-06
                           10        20
                   ....*....|....*....|....*
gi 569005368   214 LTRHIRIHTGERPFKCSECGKAFNQ 238
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1696-1720 1.34e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.51  E-value: 1.34e-05
                           10        20
                   ....*....|....*....|....*
gi 569005368  1696 LERHSRIHTGERPFHCTLCDKAFNQ 1720
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1374-1569 4.01e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 48.76  E-value: 4.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  1374 PNVQISGIDASSINNITLQIDPS----ILQQTLQQGSLLAQPITGESSTASQNSSLQTSDSTVPA---SVVIQPLSGLSL 1446
Cdd:pfam05109  567 PNATIPTLGKTSPTSAVTTPTPNatspTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTgqhNITSSSTSSMSL 646

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  1447 QPTVTSAnlTIGPLSEQDSV----LTTSS--SGSQDLSQVMTSqglvstSTGPHEITlTINNSSLSQVLAQAAGPTASSS 1520
Cdd:pfam05109  647 RPSSISE--TLSPSTSDNSTshmpLLTSAhpTGGENITQVTPA------STSTHHVS-TSSPAPRPGTTSQASGPGNSST 717

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 569005368  1521 SGSPQEITLTiselnpsSGSLP--STAPMSPSAISAQNLVMSSSGVGADAS 1569
Cdd:pfam05109  718 STKPGEVNVT-------KGTPPknATSPQAPSGQKTAVPTVTSTGGKANST 761
zf-H2C2_2 pfam13465
Zinc-finger double domain;
554-579 2.47e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.66  E-value: 2.47e-04
                           10        20
                   ....*....|....*....|....*.
gi 569005368   554 SLKVHIRLHTGVRPFACPHCDKKFRT 579
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 657-708 2.61e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 41.39  E-value: 2.61e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 569005368  657 RPYkCFYCHRAYKKSCHLKQHIRSHTgekpFKCSQCGRGFVSAGVLKAHVRT 708
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHCLQ 47
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
30-234 1.11e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.53  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368   30 DDDCPIPNFHKCEICLLSFPKESQFQRHMREHEQNDKPHRCDQCPQTFNVEFNLTLHKCTHNAEDP-----VCPV--CNK 102
Cdd:COG5048   252 DSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNHSGEslkpfSCPYslCGK 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  103 KFSRVASLKAHIMLHEKEENLICSECGDEFTLHSqlAIHMEEHRQELANTRAHTckacKKEFETSPELKEhmkTHCKVRA 182
Cdd:COG5048   332 LFSRNDALKRHILLHTSISPAKEKLLNSSSKFSP--LLNNEPPQSLQQYKDLKN----DKKSETLSNSCI---RNFKRDS 402

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 569005368  183 SGTRSYNRNIDRSSFPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGK 234
Cdd:COG5048   403 NLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1723-1748 1.66e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 1.66e-03
                           10        20
                   ....*....|....*....|....*.
gi 569005368  1723 ALQVHLKKHTGERPYRCDYCVMGFTQ 1748
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 201-246 2.04e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 2.04e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 569005368  201 CPHCGKTFQKPSQLTRHIRIHTgerpFKCSECGKAFNQKGALQTHM 246
Cdd:cd20908     4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1618-1666 2.82e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.31  E-value: 2.82e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 569005368 1618 CLDCDRAFSSAAVLMHHSKEVHGKerihgCRVCRKAFKRATHLKEHMLT 1666
Cdd:cd20908     4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1196-1245 5.14e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.54  E-value: 5.14e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 569005368 1196 KPYkCDECGKSFTVKSTLDCHVKTHTgqklFSCHVCSNAFSTKGSLKVHM 1245
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
PHA00733 PHA00733
hypothetical protein
 537-587 5.81e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.70  E-value: 5.81e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 569005368  537 IKAFKCQYCMKSFSTSGSLKVHIRL--HTGVrpfaCPHCDKKFRTSGHRKTHV 587
Cdd:PHA00733   71 VSPYVCPLCLMPFSSSVSLKQHIRYteHSKV----CPVCGKEFRNTDSTLDHV 119
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
653-1058 8.37e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 8.37e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  653 NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHVRTHTGLKSFKCLICNG-AFTTGGS 729
Cdd:COG5048    28 SNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASS 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  730 LRRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQEaSSMDDDSTVDQQSMHVAAPMPVEIESAELQ 809
Cdd:COG5048   108 SSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNS-SSVNTPQSNSLHPPLPANSLSKDPSSNLSL 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  810 QTPETVAADPESILELGPQHvvgtedaalgqQLADQPLEADEDGFTASQAPLPGHMDQFEEQGTPQPSfesagLPQGFTV 889
Cdd:COG5048   187 LISSNVSTSIPSSSENSPLS-----------SSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQ-----SPSSLSS 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  890 TDTYSQQTSFPPVQQLQDSSTLESQALSTSFHQQNLLQVPNSDAINvatrllPESSQEDlDLQTQGPQFLEDSEDQSRRS 969
Cdd:COG5048   251 SDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCN------ISFSRSS-PLTRHLRSVNHSGESLKPFS 323

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  970 YRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKS-------HEKTHTGVKAFSC--SICNASFTTNGS 1040
Cdd:COG5048   324 CPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETlsNSCIRNFKRDSN 403

                         410
                  ....*....|....*...
gi 569005368 1041 LTRHMATHMSMKPYKCPF 1058
Cdd:COG5048   404 LSLHIITHLSFRPYNCKN 421
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
197-550 4.14e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.78  E-value: 4.14e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  197 FPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 274
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  275 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPPNSTTSaeTAHVITATIFQTLPLQQVEAQVSSVS 348
Cdd:COG5048   104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNN--SSSVNTPQSNSLHPPLPANSLSKDPS 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  349 SEQSSQAVSDVIQQLLELSEPGPVEAQQSPQSgrQLSVTVGINQDILQQALENSGLSslpvaaPPSDCSHAQTATVSTQS 428
Cdd:COG5048   182 SNLSLLISSNVSTSIPSSSENSPLSSSYSIPS--SSSDQNLENSSSSLPLTTNSQLS------PKSLLSQSPSSLSSSDS 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  429 PHASSVSAEQADPMDAEQEKgqespektdkkekkllkkkSPFLPGSIREENGVRWHVCPYCTKEFRKPSDLVRHIRIHTH 508
Cdd:COG5048   254 SSSASESPRSSLPTASSQSS-------------------SPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNH 314

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 569005368  509 E----KPFKCP--QCFRAFAVKSTLTAHIKTHTGIKAFKCQY--CMKSFS 550
Cdd:COG5048   315 SgeslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFS 364
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1340-1599 1.12e-07

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.08  E-value: 1.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1340 ASVSAGGDLTVSL--TDGSL-------ATLEGIQLQLAANLVGPNVQISGIDASSINNITLQIDPSILQQTLqQGSLLAQ 1410
Cdd:COG3210   802 GTITAAGTTAINVtgSGGTItintattGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAAT-AASITVG 880

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1411 PITGESSTASQNSSLQTSDSTVPASVVIQPLSGLSLQPTVTSANLTIGPLSEQDSVLTTSSSGSQDLSQVMTSQGLVSTS 1490
Cdd:COG3210   881 SGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASAS 960

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1491 TGPHEITLTINNSSLSQVLAQAAGPTASSSSGSPQEITLTISELNPSSGSLPSTAPMSPSAISAQNLVMSSSGVGADASV 1570
Cdd:COG3210   961 DGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATA 1040

                         250       260
                  ....*....|....*....|....*....
gi 569005368 1571 TLTLADTQGVLSGGLDTVTLNITSQVTDV 1599
Cdd:COG3210  1041 GGQNGVGVNASGISGGNAAALTASGTAGT 1069
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
937-1317 2.95e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 52.01  E-value: 2.95e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  937 ATRLLPESSQEDLDLQTQGPQFLEDSEDQSRRSYRCDYCNKGFKKSSHLKQHVRSHTGEKPYKCKLCGRAFVSSGVLKSH 1016
Cdd:COG5048     1 ATLTSSQSSSSNNSVLSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1017 ---EKTHTGVKAFSCSICNASFTTNGSLTRHMATHMSMKPYKCPFCEEGfrtavhcrkHMKRHQAVSSAAAAAAETEGGD 1093
Cdd:COG5048    81 rhlRTHHNNPSDLNSKSLPLSNSKASSSSLSSSSSNSNDNNLLSSHSLP---------PSSRDPQLPDLLSISNLRNNPL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1094 TCVEEDEENSDRSASRKPRPEVITFTEEETAQLAKIqPQESATVSEKV------LVQSAAEKDRISEMKDKQAELEAEPK 1167
Cdd:COG5048   152 PGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLL-ISSNVSTSIPSssenspLSSSYSIPSSSSDQNLENSSSSLPLT 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1168 HANCCTYCPKSFKKPSDLVRHVRIHTGEKPYKCDECGKSFTVKSTLDCHVKTHTGQKLFSCH-VCSNAFSTKGSLKVHMR 1246
Cdd:COG5048   231 TNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSkQCNISFSRSSPLTRHLR 310

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 569005368 1247 --LHTG--AKPFKCPH--CELRFRTSGRRKTHMQFHYKSDPKKarKPVTRSSSESLQSVNLLNSSSTDPNVFIMNNS 1317
Cdd:COG5048   311 svNHSGesLKPFSCPYslCGKLFSRNDALKRHILLHTSISPAK--EKLLNSSSKFSPLLNNEPPQSLQQYKDLKNDK 385
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1184-1208 3.31e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.05  E-value: 3.31e-06
                           10        20
                   ....*....|....*....|....*
gi 569005368  1184 DLVRHVRIHTGEKPYKCDECGKSFT 1208
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
984-1009 7.61e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 7.61e-06
                           10        20
                   ....*....|....*....|....*.
gi 569005368   984 HLKQHVRSHTGEKPYKCKLCGRAFVS 1009
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
214-238 8.23e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.90  E-value: 8.23e-06
                           10        20
                   ....*....|....*....|....*
gi 569005368   214 LTRHIRIHTGERPFKCSECGKAFNQ 238
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1696-1720 1.34e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.51  E-value: 1.34e-05
                           10        20
                   ....*....|....*....|....*
gi 569005368  1696 LERHSRIHTGERPFHCTLCDKAFNQ 1720
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
673-698 2.09e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 2.09e-05
                           10        20
                   ....*....|....*....|....*.
gi 569005368   673 HLKQHIRSHTGEKPFKCSQCGRGFVS 698
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1374-1569 4.01e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 48.76  E-value: 4.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  1374 PNVQISGIDASSINNITLQIDPS----ILQQTLQQGSLLAQPITGESSTASQNSSLQTSDSTVPA---SVVIQPLSGLSL 1446
Cdd:pfam05109  567 PNATIPTLGKTSPTSAVTTPTPNatspTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTgqhNITSSSTSSMSL 646

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  1447 QPTVTSAnlTIGPLSEQDSV----LTTSS--SGSQDLSQVMTSqglvstSTGPHEITlTINNSSLSQVLAQAAGPTASSS 1520
Cdd:pfam05109  647 RPSSISE--TLSPSTSDNSTshmpLLTSAhpTGGENITQVTPA------STSTHHVS-TSSPAPRPGTTSQASGPGNSST 717

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 569005368  1521 SGSPQEITLTiselnpsSGSLP--STAPMSPSAISAQNLVMSSSGVGADAS 1569
Cdd:pfam05109  718 STKPGEVNVT-------KGTPPknATSPQAPSGQKTAVPTVTSTGGKANST 761
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1288-1604 6.49e-05

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 48.22  E-value: 6.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1288 VTRSSSESLQSVNLLNSSSTDPNVFIMNNSVLTGQFDQNVLQPGLVGQAILPASVSAGGDLTVSLTDGSLATLEGIQLQL 1367
Cdd:COG3210   509 GIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSA 588

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1368 AANLVGPNVQISGIDASSINNITLQIDPSILQQTLQQGSLLAQPITGESSTASQNSSLQTSDSTVPASVVIQPLSGLSLQ 1447
Cdd:COG3210   589 TGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAG 668

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1448 PTVTSANLTIGPLSEQDSVLTTSSSGSQDL-----------SQVMTSQGLVSTSTGPHEITLTINNSSLSQVLAQAAGPT 1516
Cdd:COG3210   669 GTGGGTTGTVTSGATGGTTGTTLNAATGGTlnnagntltisTGSITVTGQIGALANANGDTVTFGNLGTGATLTLNAGVT 748

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368 1517 ASS-SSGSP------------QEITLTISELNPSSGSL--PSTAPMSPSAISAQNLVMSSSGV----GADASVTLTLADT 1577
Cdd:COG3210   749 ITSgNAGTLsigltanttasgTTLTLANANGNTSAGATldNAGAEISIDITADGTITAAGTTAinvtGSGGTITINTATT 828

                         330       340
                  ....*....|....*....|....*..
gi 569005368 1578 qGVLSGGLDTVTLNITSQVTDVPAQLT 1604
Cdd:COG3210   829 -GLTGTGDTTSGAGGSNTTDTTTGTTS 854
zf-H2C2_2 pfam13465
Zinc-finger double domain;
554-579 2.47e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.66  E-value: 2.47e-04
                           10        20
                   ....*....|....*....|....*.
gi 569005368   554 SLKVHIRLHTGVRPFACPHCDKKFRT 579
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 657-708 2.61e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 41.39  E-value: 2.61e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 569005368  657 RPYkCFYCHRAYKKSCHLKQHIRSHTgekpFKCSQCGRGFVSAGVLKAHVRT 708
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHCLQ 47
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 199-221 2.72e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 39.59  E-value: 2.72e-04
                           10        20
                   ....*....|....*....|...
gi 569005368   199 YSCPHCGKTFQKPSQLTRHIRIH 221
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1040-1065 4.41e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 4.41e-04
                           10        20
                   ....*....|....*....|....*.
gi 569005368  1040 SLTRHMATHMSMKPYKCPFCEEGFRT 1065
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 685-734 5.55e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.23  E-value: 5.55e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 569005368  685 KPFkCSQCGRGFVSAGVLKAHVRTHTglksFKCLICNGAFTTGGSLRRHM 734
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1240-1265 6.86e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 6.86e-04
                           10        20
                   ....*....|....*....|....*.
gi 569005368  1240 SLKVHMRLHTGAKPFKCPHCELRFRT 1265
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 972-1016 7.10e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 40.23  E-value: 7.10e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 569005368  972 CDYCNKGFKKSSHLKQHVRSHTgekpYKCKLCGRAFVSSGVLKSH 1016
Cdd:cd20908     4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
30-234 1.11e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.53  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368   30 DDDCPIPNFHKCEICLLSFPKESQFQRHMREHEQNDKPHRCDQCPQTFNVEFNLTLHKCTHNAEDP-----VCPV--CNK 102
Cdd:COG5048   252 DSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNHSGEslkpfSCPYslCGK 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  103 KFSRVASLKAHIMLHEKEENLICSECGDEFTLHSqlAIHMEEHRQELANTRAHTckacKKEFETSPELKEhmkTHCKVRA 182
Cdd:COG5048   332 LFSRNDALKRHILLHTSISPAKEKLLNSSSKFSP--LLNNEPPQSLQQYKDLKN----DKKSETLSNSCI---RNFKRDS 402

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 569005368  183 SGTRSYNRNIDRSSFPYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGK 234
Cdd:COG5048   403 NLSLHIITHLSFRPYNCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS 454
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 970-992 1.51e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 37.66  E-value: 1.51e-03
                           10        20
                   ....*....|....*....|...
gi 569005368   970 YRCDYCNKGFKKSSHLKQHVRSH 992
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1723-1748 1.66e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 1.66e-03
                           10        20
                   ....*....|....*....|....*.
gi 569005368  1723 ALQVHLKKHTGERPYRCDYCVMGFTQ 1748
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 201-246 2.04e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 2.04e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 569005368  201 CPHCGKTFQKPSQLTRHIRIHTgerpFKCSECGKAFNQKGALQTHM 246
Cdd:cd20908     4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 227-249 2.75e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.89  E-value: 2.75e-03
                           10        20
                   ....*....|....*....|...
gi 569005368   227 FKCSECGKAFNQKGALQTHMIKH 249
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1618-1666 2.82e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.31  E-value: 2.82e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 569005368 1618 CLDCDRAFSSAAVLMHHSKEVHGKerihgCRVCRKAFKRATHLKEHMLT 1666
Cdd:cd20908     4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 484-506 3.51e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.51  E-value: 3.51e-03
                           10        20
                   ....*....|....*....|...
gi 569005368   484 HVCPYCTKEFRKPSDLVRHIRIH 506
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 510-558 3.86e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.92  E-value: 3.86e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 569005368  510 KPFkCPQCFRAFAVKSTLTAHIKTHTgikaFKCQYCMKSFSTSGSLKVH 558
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
50-320 4.79e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.61  E-value: 4.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368   50 KESQFQRHMREHEQNDKPHRCDQCPQTFNVEFNLTLHKCTHNAEDP-VCPV--CNKKFSRVASLKAHIMLH--------- 117
Cdd:COG5048    16 LSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPsQCSYsgCDKSFSRPLELSRHLRTHhnnpsdlns 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  118 ----------EKEENLICSECGDEFTLHSQLAIHMEEHRQELANTRAHT-------------CKACKKEFETSPELKEHM 174
Cdd:COG5048    96 kslplsnskaSSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISnlrnnplpgnnssSVNTPQSNSLHPPLPANS 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569005368  175 KTHCKVRASGTRSYNRNIDRSSFPYSCPHCGKTFQKPSQLTRHIRIH-TGERPFKCSECGKAFNQKGALQTHmIKHTGEK 253
Cdd:COG5048   176 LSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENsSSSLPLTTNSQLSPKSLLSQSPSS-LSSSDSS 254

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 569005368  254 PHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPT--YNCTECSCVFKSLGSLNTHISKMHMGGPPNSTTS 320
Cdd:COG5048   255 SSASESPRSSLPTASSQSSSPNESDSSSEKGFSlpIKSKQCNISFSRSSPLTRHLRSVNHSGESLKPFS 323
zf-H2C2_2 pfam13465
Zinc-finger double domain;
729-754 5.03e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 5.03e-03
                           10        20
                   ....*....|....*....|....*.
gi 569005368   729 SLRRHMGIHNDLRPYMCPYCQKTFKT 754
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1196-1245 5.14e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.54  E-value: 5.14e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 569005368 1196 KPYkCDECGKSFTVKSTLDCHVKTHTgqklFSCHVCSNAFSTKGSLKVHM 1245
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
PHA00733 PHA00733
hypothetical protein
 537-587 5.81e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 38.70  E-value: 5.81e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 569005368  537 IKAFKCQYCMKSFSTSGSLKVHIRL--HTGVrpfaCPHCDKKFRTSGHRKTHV 587
Cdd:PHA00733   71 VSPYVCPLCLMPFSSSVSLKQHIRYteHSKV----CPVCGKEFRNTDSTLDHV 119
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1673-1742 6.86e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.22  E-value: 6.86e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 569005368 1673 LSSQKPRVFKCDSCEKAFAKPSQLERHSRIHTGERPFHCTL--CDKAFNQKSALQVHLKKHTGERPYRCDYC 1742
Cdd:COG5048    26 SLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKS 97
zf-H2C2_2 pfam13465
Zinc-finger double domain;
527-551 9.08e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 9.08e-03
                           10        20
                   ....*....|....*....|....*
gi 569005368   527 LTAHIKTHTGIKAFKCQYCMKSFST 551
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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