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Conserved domains on  [gi|569003891|ref|XP_006526012|]
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histone deacetylase complex subunit SAP130 isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SAP130_C pfam16014
Histone deacetylase complex subunit SAP130 C-terminus;
655-1060 0e+00

Histone deacetylase complex subunit SAP130 C-terminus;


:

Pssm-ID: 464973 [Multi-domain]  Cd Length: 371  Bit Score: 550.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   655 AQGSSPRPSILRKKPATDGmavrktllppqppdvatprvessmrsasgsprpagAKPKSEVHVSIATPVTVSLETISNQN 734
Cdd:pfam16014    1 ALGSSPRPSILRKKPATEG-----------------------------------AKPKPDIHVAVAPPVTVAVEALPGQN 45
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   735 AEQPTVAVPPTAQQPPPTIPSMIAAASPPSQPAIALSTIPGAVPVTPP----ITTIAATPTLSApVGGTPSTVLGPPVPE 810
Cdd:pfam16014   46 SEQQTASASPPSQHPAQAIPTILAPAAPPSQPSVVLSTLPAAMAVTPPipasMANVVAPPTQPA-ASSTAACAVSSVLPE 124
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   811 IKVKEEAEPVDITRpvsTVPPLATNTVSPSLALLASNLSMPPSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKS 890
Cdd:pfam16014  125 IKIKQEAEPMDTSQ---SVPPLTPTSISPALTSLANNLSVPAGDLLPGASPRKKPRKQQHVISTEEGEMMETNSTDEEKS 201
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   891 AAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSC 970
Cdd:pfam16014  202 APKPLTSRAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKGTLQDMANQKGVTC 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   971 RAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLD 1050
Cdd:pfam16014  282 RAQGWKIHLCAAQLLQLTNLEHDVYSRLTTLQEGLIPKKKAGTDDDLHRINELIQGNMQRCKLVMDQITEARDSMMKVLD 361
                          410
                   ....*....|
gi 569003891  1051 HKDRVLKLLN 1060
Cdd:pfam16014  362 HKDRVLKLLN 371
PHA03247 super family cl33720
large tegument protein UL36; Provisional
437-906 8.59e-07

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 8.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  437 PRIQPDYPPERSSLIPiSGHRASPNPVAMETRNDNRPSVPVQfqyflPTYPPSAYPlaahTYTPITSSVSTIRQYPVSAQ 516
Cdd:PHA03247 2641 HPPPTVPPPERPRDDP-APGRVSRPRRARRLGRAAQASSPPQ-----RPRRRAARP----TVGSLTSLADPPPPPPTPEP 2710
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  517 APNSTITAqtgvgvastvhlNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGtsgiqPAPIGTPGIHSAAPINTQGL 596
Cdd:PHA03247 2711 APHALVSA------------TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG-----PARPARPPTTAGPPAPAPPA 2773
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  597 QPAAmanqQPQPEGKTSAVVLADGATivaNPISNPFSAAPAATTVVQTHSQSASTNTPAQGSSPRPSILRKKPATdgmav 676
Cdd:PHA03247 2774 APAA----GPPRRLTRPAVASLSESR---ESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPP----- 2841
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  677 rktllPPQPPDVATPR----VESSMRSASGSPRPAGAKPKSEVHVSIATPVTVSLETiSNQNAEQPTVAVPPTAQQPPPT 752
Cdd:PHA03247 2842 -----PPGPPPPSLPLggsvAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSR-STESFALPPDQPERPPQPQAPP 2915
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  753 IPSMIAAASPPSQPAIALSTIPGAVPVTPPITTIAATPtlsAPVGGTPSTVLGP------PVPEIKVKEEAEPVDItrPV 826
Cdd:PHA03247 2916 PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAG---EPSGAVPQPWLGAlvpgrvAVPRFRVPQPAPSREA--PA 2990
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  827 STVPPLaTNTVSPSLALLASNLSMPPSDLPPGASprkkpRKQQHVIS--TEEGDMMETNSTDDEKSAAKSLLVKAEKRKS 904
Cdd:PHA03247 2991 SSTPPL-TGHSLSRVSSWASSLALHEETDPPPVS-----LKQTLWPPddTEDSDADSLFDSDSERSDLEALDPLPPEPHD 3064

                  ..
gi 569003891  905 PP 906
Cdd:PHA03247 3065 PF 3066
PHA03247 super family cl33720
large tegument protein UL36; Provisional
8-359 2.34e-05

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 2.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891    8 RLRIPQASGLNVEMSSQQFPRLGTPSPGLSQPPSQIASSGSAGLINQVATVNDEAGRDADVGTREHVGPSSSLPPREEKQ 87
Cdd:PHA03247 2597 RPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQA 2676
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   88 EPVVVRPYPQVQMLPAHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTMSlPPKVPGQVT 167
Cdd:PHA03247 2677 SSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPA-GPATPGGPA 2755
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  168 VTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRgaaaaavmsSSKVTTVLRPTS 247
Cdd:PHA03247 2756 RPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAP---------AAALPPAASPAG 2826
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  248 QLPNAATAQPAVQHLIHQPIQsrPPVTTSSTIPPAVVATVSATRAQSPVITTTAAHAADSTLSRPTLSIQHPPSA--AIS 325
Cdd:PHA03247 2827 PLPPPTSAQPTAPPPPPGPPP--PSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQ 2904
                         330       340       350
                  ....*....|....*....|....*....|....
gi 569003891  326 IQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQ 359
Cdd:PHA03247 2905 PERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR 2938
 
Name Accession Description Interval E-value
SAP130_C pfam16014
Histone deacetylase complex subunit SAP130 C-terminus;
655-1060 0e+00

Histone deacetylase complex subunit SAP130 C-terminus;


Pssm-ID: 464973 [Multi-domain]  Cd Length: 371  Bit Score: 550.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   655 AQGSSPRPSILRKKPATDGmavrktllppqppdvatprvessmrsasgsprpagAKPKSEVHVSIATPVTVSLETISNQN 734
Cdd:pfam16014    1 ALGSSPRPSILRKKPATEG-----------------------------------AKPKPDIHVAVAPPVTVAVEALPGQN 45
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   735 AEQPTVAVPPTAQQPPPTIPSMIAAASPPSQPAIALSTIPGAVPVTPP----ITTIAATPTLSApVGGTPSTVLGPPVPE 810
Cdd:pfam16014   46 SEQQTASASPPSQHPAQAIPTILAPAAPPSQPSVVLSTLPAAMAVTPPipasMANVVAPPTQPA-ASSTAACAVSSVLPE 124
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   811 IKVKEEAEPVDITRpvsTVPPLATNTVSPSLALLASNLSMPPSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKS 890
Cdd:pfam16014  125 IKIKQEAEPMDTSQ---SVPPLTPTSISPALTSLANNLSVPAGDLLPGASPRKKPRKQQHVISTEEGEMMETNSTDEEKS 201
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   891 AAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSC 970
Cdd:pfam16014  202 APKPLTSRAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKGTLQDMANQKGVTC 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   971 RAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLD 1050
Cdd:pfam16014  282 RAQGWKIHLCAAQLLQLTNLEHDVYSRLTTLQEGLIPKKKAGTDDDLHRINELIQGNMQRCKLVMDQITEARDSMMKVLD 361
                          410
                   ....*....|
gi 569003891  1051 HKDRVLKLLN 1060
Cdd:pfam16014  362 HKDRVLKLLN 371
PHA03247 PHA03247
large tegument protein UL36; Provisional
437-906 8.59e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 8.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  437 PRIQPDYPPERSSLIPiSGHRASPNPVAMETRNDNRPSVPVQfqyflPTYPPSAYPlaahTYTPITSSVSTIRQYPVSAQ 516
Cdd:PHA03247 2641 HPPPTVPPPERPRDDP-APGRVSRPRRARRLGRAAQASSPPQ-----RPRRRAARP----TVGSLTSLADPPPPPPTPEP 2710
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  517 APNSTITAqtgvgvastvhlNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGtsgiqPAPIGTPGIHSAAPINTQGL 596
Cdd:PHA03247 2711 APHALVSA------------TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG-----PARPARPPTTAGPPAPAPPA 2773
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  597 QPAAmanqQPQPEGKTSAVVLADGATivaNPISNPFSAAPAATTVVQTHSQSASTNTPAQGSSPRPSILRKKPATdgmav 676
Cdd:PHA03247 2774 APAA----GPPRRLTRPAVASLSESR---ESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPP----- 2841
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  677 rktllPPQPPDVATPR----VESSMRSASGSPRPAGAKPKSEVHVSIATPVTVSLETiSNQNAEQPTVAVPPTAQQPPPT 752
Cdd:PHA03247 2842 -----PPGPPPPSLPLggsvAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSR-STESFALPPDQPERPPQPQAPP 2915
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  753 IPSMIAAASPPSQPAIALSTIPGAVPVTPPITTIAATPtlsAPVGGTPSTVLGP------PVPEIKVKEEAEPVDItrPV 826
Cdd:PHA03247 2916 PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAG---EPSGAVPQPWLGAlvpgrvAVPRFRVPQPAPSREA--PA 2990
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  827 STVPPLaTNTVSPSLALLASNLSMPPSDLPPGASprkkpRKQQHVIS--TEEGDMMETNSTDDEKSAAKSLLVKAEKRKS 904
Cdd:PHA03247 2991 SSTPPL-TGHSLSRVSSWASSLALHEETDPPPVS-----LKQTLWPPddTEDSDADSLFDSDSERSDLEALDPLPPEPHD 3064

                  ..
gi 569003891  905 PP 906
Cdd:PHA03247 3065 PF 3066
PHA03247 PHA03247
large tegument protein UL36; Provisional
578-869 2.44e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 52.25  E-value: 2.44e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  578 APIGTPGiHSAAPINTQGLQPAAMANQQPQPEGKTSAVVLADGATIVANPISNPFSAApaATTVVQTHSQSASTNTPAQG 657
Cdd:PHA03247 2600 APVDDRG-DPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDP--APGRVSRPRRARRLGRAAQA 2676
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  658 SSPrPSILRKKPATDGMAVRKTLLPPQPPdvatprvessmrsasgsPRPAGAKPKSEVHVSIATPVTVSletiSNQNAEQ 737
Cdd:PHA03247 2677 SSP-PQRPRRRAARPTVGSLTSLADPPPP-----------------PPTPEPAPHALVSATPLPPGPAA----ARQASPA 2734
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  738 PTVAVPPTAQQPPPTIPSMIAAASPPSQPAIALSTIPGAVPVT--PPITTIAATPTLSAPVGGTPSTVLGPPVPEIKVKE 815
Cdd:PHA03247 2735 LPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAgpPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAP 2814
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 569003891  816 EAEPVDITRPVSTVPPLATNT-VSPSLALLASNLSMPP-SDLPPGASPRKKPRKQQ 869
Cdd:PHA03247 2815 AAALPPAASPAGPLPPPTSAQpTAPPPPPGPPPPSLPLgGSVAPGGDVRRRPPSRS 2870
PHA03247 PHA03247
large tegument protein UL36; Provisional
8-359 2.34e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 2.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891    8 RLRIPQASGLNVEMSSQQFPRLGTPSPGLSQPPSQIASSGSAGLINQVATVNDEAGRDADVGTREHVGPSSSLPPREEKQ 87
Cdd:PHA03247 2597 RPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQA 2676
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   88 EPVVVRPYPQVQMLPAHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTMSlPPKVPGQVT 167
Cdd:PHA03247 2677 SSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPA-GPATPGGPA 2755
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  168 VTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRgaaaaavmsSSKVTTVLRPTS 247
Cdd:PHA03247 2756 RPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAP---------AAALPPAASPAG 2826
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  248 QLPNAATAQPAVQHLIHQPIQsrPPVTTSSTIPPAVVATVSATRAQSPVITTTAAHAADSTLSRPTLSIQHPPSA--AIS 325
Cdd:PHA03247 2827 PLPPPTSAQPTAPPPPPGPPP--PSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQ 2904
                         330       340       350
                  ....*....|....*....|....*....|....
gi 569003891  326 IQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQ 359
Cdd:PHA03247 2905 PERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR 2938
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
473-849 2.37e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 45.53  E-value: 2.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   473 PSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQ-YPVSAQAPNSTI-TAQTGVGVASTVHLNPMQLMTvdashar 550
Cdd:pfam03154  172 PVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQgSPATSQPPNQTQsTAAPHTLIQQTPTLHPQRLPS------- 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   551 hiqgiqPAPISTQGIQPAPIGTSGIQPAPigTPGIHSAAPINTQGLQPAAMANQQPQPEgktsavvladgATIVANPISN 630
Cdd:pfam03154  245 ------PHPPLQPMTQPPPPSQVSPQPLP--QPSLHGQMPPMPHSLQTGPSHMQHPVPP-----------QPFPLTPQSS 305
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   631 PFSAAPAATTVVQTHSQSASTNTPAQGSSPRPSILRKKPATDG-MAVRKTLLPPQPPDVATPRVESSMRSA--------- 700
Cdd:pfam03154  306 QSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPApLSMPHIKPPPTTPIPQLPNPQSHKHPPhlsgpspfq 385
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   701 --SGSPRPAGAKPKSEV---HVSIATPVTVSLETISNQ----NAEQPTVAVPPTAQQPPPTIPSMIAAASPPSQPAIAL- 770
Cdd:pfam03154  386 mnSNLPPPPALKPLSSLsthHPPSAHPPPLQLMPQSQQlpppPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQh 465
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   771 STIPGAVPV-----TPPITTIAATPTLSAPVGGTPST------VLGPPVPEIKVKEEAePVDITRPVSTVPPLATNTVSP 839
Cdd:pfam03154  466 PFVPGGPPPitppsGPPTSTSSAMPGIQPPSSASVSSsgpvpaAVSCPLPPVQIKEEA-LDEAEEPESPPPPPRSPSPEP 544
                          410
                   ....*....|
gi 569003891   840 SLALLASNLS 849
Cdd:pfam03154  545 TVVNTPSHAS 554
 
Name Accession Description Interval E-value
SAP130_C pfam16014
Histone deacetylase complex subunit SAP130 C-terminus;
655-1060 0e+00

Histone deacetylase complex subunit SAP130 C-terminus;


Pssm-ID: 464973 [Multi-domain]  Cd Length: 371  Bit Score: 550.69  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   655 AQGSSPRPSILRKKPATDGmavrktllppqppdvatprvessmrsasgsprpagAKPKSEVHVSIATPVTVSLETISNQN 734
Cdd:pfam16014    1 ALGSSPRPSILRKKPATEG-----------------------------------AKPKPDIHVAVAPPVTVAVEALPGQN 45
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   735 AEQPTVAVPPTAQQPPPTIPSMIAAASPPSQPAIALSTIPGAVPVTPP----ITTIAATPTLSApVGGTPSTVLGPPVPE 810
Cdd:pfam16014   46 SEQQTASASPPSQHPAQAIPTILAPAAPPSQPSVVLSTLPAAMAVTPPipasMANVVAPPTQPA-ASSTAACAVSSVLPE 124
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   811 IKVKEEAEPVDITRpvsTVPPLATNTVSPSLALLASNLSMPPSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKS 890
Cdd:pfam16014  125 IKIKQEAEPMDTSQ---SVPPLTPTSISPALTSLANNLSVPAGDLLPGASPRKKPRKQQHVISTEEGEMMETNSTDEEKS 201
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   891 AAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSC 970
Cdd:pfam16014  202 APKPLTSRAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKKGTLQDMANQKGVTC 281
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   971 RAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLD 1050
Cdd:pfam16014  282 RAQGWKIHLCAAQLLQLTNLEHDVYSRLTTLQEGLIPKKKAGTDDDLHRINELIQGNMQRCKLVMDQITEARDSMMKVLD 361
                          410
                   ....*....|
gi 569003891  1051 HKDRVLKLLN 1060
Cdd:pfam16014  362 HKDRVLKLLN 371
PHA03247 PHA03247
large tegument protein UL36; Provisional
437-906 8.59e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 53.40  E-value: 8.59e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  437 PRIQPDYPPERSSLIPiSGHRASPNPVAMETRNDNRPSVPVQfqyflPTYPPSAYPlaahTYTPITSSVSTIRQYPVSAQ 516
Cdd:PHA03247 2641 HPPPTVPPPERPRDDP-APGRVSRPRRARRLGRAAQASSPPQ-----RPRRRAARP----TVGSLTSLADPPPPPPTPEP 2710
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  517 APNSTITAqtgvgvastvhlNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGtsgiqPAPIGTPGIHSAAPINTQGL 596
Cdd:PHA03247 2711 APHALVSA------------TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGG-----PARPARPPTTAGPPAPAPPA 2773
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  597 QPAAmanqQPQPEGKTSAVVLADGATivaNPISNPFSAAPAATTVVQTHSQSASTNTPAQGSSPRPSILRKKPATdgmav 676
Cdd:PHA03247 2774 APAA----GPPRRLTRPAVASLSESR---ESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPP----- 2841
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  677 rktllPPQPPDVATPR----VESSMRSASGSPRPAGAKPKSEVHVSIATPVTVSLETiSNQNAEQPTVAVPPTAQQPPPT 752
Cdd:PHA03247 2842 -----PPGPPPPSLPLggsvAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSR-STESFALPPDQPERPPQPQAPP 2915
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  753 IPSMIAAASPPSQPAIALSTIPGAVPVTPPITTIAATPtlsAPVGGTPSTVLGP------PVPEIKVKEEAEPVDItrPV 826
Cdd:PHA03247 2916 PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAG---EPSGAVPQPWLGAlvpgrvAVPRFRVPQPAPSREA--PA 2990
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  827 STVPPLaTNTVSPSLALLASNLSMPPSDLPPGASprkkpRKQQHVIS--TEEGDMMETNSTDDEKSAAKSLLVKAEKRKS 904
Cdd:PHA03247 2991 SSTPPL-TGHSLSRVSSWASSLALHEETDPPPVS-----LKQTLWPPddTEDSDADSLFDSDSERSDLEALDPLPPEPHD 3064

                  ..
gi 569003891  905 PP 906
Cdd:PHA03247 3065 PF 3066
PHA03247 PHA03247
large tegument protein UL36; Provisional
578-869 2.44e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 52.25  E-value: 2.44e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  578 APIGTPGiHSAAPINTQGLQPAAMANQQPQPEGKTSAVVLADGATIVANPISNPFSAApaATTVVQTHSQSASTNTPAQG 657
Cdd:PHA03247 2600 APVDDRG-DPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDP--APGRVSRPRRARRLGRAAQA 2676
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  658 SSPrPSILRKKPATDGMAVRKTLLPPQPPdvatprvessmrsasgsPRPAGAKPKSEVHVSIATPVTVSletiSNQNAEQ 737
Cdd:PHA03247 2677 SSP-PQRPRRRAARPTVGSLTSLADPPPP-----------------PPTPEPAPHALVSATPLPPGPAA----ARQASPA 2734
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  738 PTVAVPPTAQQPPPTIPSMIAAASPPSQPAIALSTIPGAVPVT--PPITTIAATPTLSAPVGGTPSTVLGPPVPEIKVKE 815
Cdd:PHA03247 2735 LPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAgpPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAP 2814
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 569003891  816 EAEPVDITRPVSTVPPLATNT-VSPSLALLASNLSMPP-SDLPPGASPRKKPRKQQ 869
Cdd:PHA03247 2815 AAALPPAASPAGPLPPPTSAQpTAPPPPPGPPPPSLPLgGSVAPGGDVRRRPPSRS 2870
PHA03247 PHA03247
large tegument protein UL36; Provisional
8-359 2.34e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.78  E-value: 2.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891    8 RLRIPQASGLNVEMSSQQFPRLGTPSPGLSQPPSQIASSGSAGLINQVATVNDEAGRDADVGTREHVGPSSSLPPREEKQ 87
Cdd:PHA03247 2597 RPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQA 2676
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   88 EPVVVRPYPQVQMLPAHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTMSlPPKVPGQVT 167
Cdd:PHA03247 2677 SSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPA-GPATPGGPA 2755
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  168 VTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRgaaaaavmsSSKVTTVLRPTS 247
Cdd:PHA03247 2756 RPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAP---------AAALPPAASPAG 2826
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  248 QLPNAATAQPAVQHLIHQPIQsrPPVTTSSTIPPAVVATVSATRAQSPVITTTAAHAADSTLSRPTLSIQHPPSA--AIS 325
Cdd:PHA03247 2827 PLPPPTSAQPTAPPPPPGPPP--PSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFAlpPDQ 2904
                         330       340       350
                  ....*....|....*....|....*....|....
gi 569003891  326 IQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQ 359
Cdd:PHA03247 2905 PERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR 2938
PHA03247 PHA03247
large tegument protein UL36; Provisional
118-512 9.72e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 9.72e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  118 PPAHLTPA---------VPLSFSEGLMKPPPKPTMPSRPIAPAPPSTMSLPPKVPGQVTVTMESS-IPQASAIPVATISG 187
Cdd:PHA03247 2551 PPPPLPPAappaapdrsVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSpLPPDTHAPDPPPPS 2630
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  188 QQGHPSNLHHIMTTNVQMSIIRSNAPGPP------------LHIGASHLPRGAAAAAVMSS-SKVTTVLRPTSQLPNAAT 254
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVPPPERPRDDPAPGrvsrprrarrlgRAAQASSPPQRPRRRAARPTvGSLTSLADPPPPPPTPEP 2710
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  255 AQPAVQHLIHQPIQSRPPVTTSSTIPPAVVATVSATRAQSPV-ITTTAAHAADSTLSRPTLSIQHPPSAAISIQRPAQSR 333
Cdd:PHA03247 2711 APHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGgPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVAS 2790
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  334 DVTTRITLPS------HPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTLPSTTTAGSVSHTQAPtstiVTMTM 407
Cdd:PHA03247 2791 LSESRESLPSpwdpadPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGD----VRRRP 2866
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  408 PSHSSHATAVTTSNIPVAKVvpqqithtsPRIQPDYPPERSSLIPISGHRASPNPVAMETRNDNRPSVPVQFQYFLPTYP 487
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRL---------ARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPP 2937
                         410       420
                  ....*....|....*....|....*
gi 569003891  488 PSAYPLAAHTYTPITSSVSTIRQYP 512
Cdd:PHA03247 2938 RPQPPLAPTTDPAGAGEPSGAVPQP 2962
Atrophin-1 pfam03154
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
473-849 2.37e-04

Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.


Pssm-ID: 460830 [Multi-domain]  Cd Length: 991  Bit Score: 45.53  E-value: 2.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   473 PSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQ-YPVSAQAPNSTI-TAQTGVGVASTVHLNPMQLMTvdashar 550
Cdd:pfam03154  172 PVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQgSPATSQPPNQTQsTAAPHTLIQQTPTLHPQRLPS------- 244
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   551 hiqgiqPAPISTQGIQPAPIGTSGIQPAPigTPGIHSAAPINTQGLQPAAMANQQPQPEgktsavvladgATIVANPISN 630
Cdd:pfam03154  245 ------PHPPLQPMTQPPPPSQVSPQPLP--QPSLHGQMPPMPHSLQTGPSHMQHPVPP-----------QPFPLTPQSS 305
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   631 PFSAAPAATTVVQTHSQSASTNTPAQGSSPRPSILRKKPATDG-MAVRKTLLPPQPPDVATPRVESSMRSA--------- 700
Cdd:pfam03154  306 QSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPApLSMPHIKPPPTTPIPQLPNPQSHKHPPhlsgpspfq 385
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   701 --SGSPRPAGAKPKSEV---HVSIATPVTVSLETISNQ----NAEQPTVAVPPTAQQPPPTIPSMIAAASPPSQPAIAL- 770
Cdd:pfam03154  386 mnSNLPPPPALKPLSSLsthHPPSAHPPPLQLMPQSQQlpppPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQh 465
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891   771 STIPGAVPV-----TPPITTIAATPTLSAPVGGTPST------VLGPPVPEIKVKEEAePVDITRPVSTVPPLATNTVSP 839
Cdd:pfam03154  466 PFVPGGPPPitppsGPPTSTSSAMPGIQPPSSASVSSsgpvpaAVSCPLPPVQIKEEA-LDEAEEPESPPPPPRSPSPEP 544
                          410
                   ....*....|
gi 569003891   840 SLALLASNLS 849
Cdd:pfam03154  545 TVVNTPSHAS 554
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
551-866 3.97e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.31  E-value: 3.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  551 HIQGIQPAPISTQGIQPAPIGTSGIQPAPIGTPGihSAAPINTQGLQPAAMANQQPQPEGKTSAVVLADGATIVANPISN 630
Cdd:PHA03307   91 SLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPA--SPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAAS 168
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  631 PFSAAPAATTVVQTHSQSASTNTPAQGSSPRPSilrkkpatdgmavrktlLPPQPPDVATPRVESSMRSASGSPRPAGAK 710
Cdd:PHA03307  169 SRQAALPLSSPEETARAPSSPPAEPPPSTPPAA-----------------ASPRPPRRSSPISASASSPAPAPGRSAADD 231
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  711 PKSEVHVSIATPVTVSLETISNQNAEQPtvavpptaqqppptiPSMIAAASPPSQPAIALSTIPGAVPVTPPITTIAATP 790
Cdd:PHA03307  232 AGASSSDSSSSESSGCGWGPENECPLPR---------------PAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSP 296
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 569003891  791 TLSAPVGGTPSTVLGPPVPEIKVKEEAEPVDITRPVSTVPPLATNTVSPSLALLASnlSMPPSDLPPGASPRKKPR 866
Cdd:PHA03307  297 SPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPS--PSRPPPPADPSSPRKRPR 370
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
761-881 4.23e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 40.95  E-value: 4.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  761 SPPSQPAIALSTIPGAVPVTPPITTIAATPTLSAPVGGTPSTVLGPPVPEIKVKEEAEPV--DITRPVSTVPPLATNTVS 838
Cdd:PRK14950  344 TSYGQLPLELAVIEALLVPVPAPQPAKPTAAAPSPVRPTPAPSTRPKAAAAANIPPKEPVreTATPPPVPPRPVAPPVPH 423
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 569003891  839 PSLALLASNLSMPPSDLPPGASPrKKPRKQQHVISTEEGDMME 881
Cdd:PRK14950  424 TPESAPKLTRAAIPVDEKPKYTP-PAPPKEEEKALIADGDVLE 465
PHA02732 PHA02732
hypothetical protein; Provisional
257-486 5.13e-03

hypothetical protein; Provisional


Pssm-ID: 165099 [Multi-domain]  Cd Length: 1467  Bit Score: 40.89  E-value: 5.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  257 PAVQHLIHQPIQSRPPVTTSST--IPPAVVA----TVSATRAQSPVITTTAAHAADSTLSRPTLSIQHPPSAAISIQrPA 330
Cdd:PHA02732 1182 PAPQLLSSYIPTGSVLYQDPIFtyIPPGIIGmsgtNTFTFKAAQLQLSAASSPPAATTPTPPPSSSSSSSAQSISTS-PG 1260
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  331 QSR-----DVTTRITLPSHPALGTPKqqlhtmaqktifsTGTPVAAATVapilatntlpSTTTAGSVSHTQAPTSTIVTM 405
Cdd:PHA02732 1261 QIQivlngSTTIHINFLFFPALSTPK-------------IGQILAMPIV----------NSSGAFISLYVNSAISANFNV 1317
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003891  406 TMPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPPErSSLIPISGHRASPNPVAMETRNDNRPSVPVQFQYFLPT 485
Cdd:PHA02732 1318 TIEYVFSNGTVIKRFTDEPGQIFPLPLINGDEEVIISVENE-STTFNISANNLGSAQLALQLRNAISASLPGPFAFFGPI 1396

                  .
gi 569003891  486 Y 486
Cdd:PHA02732 1397 L 1397
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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