|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
67-322 |
7.68e-29 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 120.04 E-value: 7.68e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 67 PNTIPELTQRLDLQGNILKVLPAAAFQDLPHLTHLDLRNCQvemvaegAFRGLGRLLLLNLASNRLSTLPqEALDGLGSL 146
Cdd:COG4886 67 LLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLP-EELANLTNL 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 147 RRLELEGNMLEELrPGTFGALGSLTTLNLAHNALVYLPAmAFQGLLRTRWLQLSHNALSVLaPEALAGLPALRRLSLHHN 226
Cdd:COG4886 139 KELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGN 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 227 ELQALPgAALSQARSLARLELGHNPLTytgeedglALPGLRELaldhgslqalgprafahcPRLHTLDLRGNQLTTLPPL 306
Cdd:COG4886 216 QLTDLP-EPLANLTNLETLDLSNNQLT--------DLPELGNL------------------TNLEELDLSNNQLTDLPPL 268
|
250
....*....|....*.
gi 568991976 307 QVPGQLRRLRLQGNPL 322
Cdd:COG4886 269 ANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
455-687 |
2.62e-28 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 118.50 E-value: 2.62e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 455 FPGLRHLVSLHLQHCGvaelepgALAGLDRLLYLYLSHNQLSGLSAAaLEGAPNLGYLYLEHNRFLRIPgTALRALPTLV 534
Cdd:COG4886 92 LGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLSNNQLTDLP-EPLGNLTNLK 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 535 SLHLQDNAVDRLaPGDLAGARALRCLYLSGNHITQVsPGALGPARELEKLHLDRNRLREVPTgALEGLPALKELQLSGNP 614
Cdd:COG4886 163 SLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQ 239
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568991976 615 LRALPdgafqpvgrSLQQLflnssdleqisprafsglgKGLRSLYLHKNQLQSLPAPLGLSGLELVDLSGNPF 687
Cdd:COG4886 240 LTDLP---------ELGNL-------------------TNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQL 284
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
418-615 |
2.92e-16 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 78.29 E-value: 2.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 418 HSTCDGRGLQAVP--RGFPNdTQLLDLRRNHFPSVPraAFPGLRHLVSLHLQHCGVAELEPgaLAGLDRLLYLYLSHNQL 495
Cdd:cd21340 6 HLYLNDKNITKIDnlSLCKN-LKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 496 SGLSaaALEGAPNLGYLYLEHNRflripgtalraLPTLVSLHLQDNAVDRLAPgdlagarALRCLYLSGNHITQVSPgaL 575
Cdd:cd21340 81 SVVE--GLENLTNLEELHIENQR-----------LPPGEKLTFDPRSLAALSN-------SLRVLNISGNNIDSLEP--L 138
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 568991976 576 GPARELEKLHLDRNRLREVP--TGALEGLPALKELQLSGNPL 615
Cdd:cd21340 139 APLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
169-228 |
2.18e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 62.54 E-value: 2.18e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 169 SLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNEL 228
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
459-519 |
2.41e-11 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 59.46 E-value: 2.41e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568991976 459 RHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRF 519
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
426-652 |
6.03e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 65.87 E-value: 6.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 426 LQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPgalaglDRLLYLYLSHNQLSGLSAAALEG 505
Cdd:PRK15370 232 LTSIPATLPDTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENLP------EELRYLSVYDNSIRTLPAHLPSG 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 506 apnLGYLYLEHNRFLRIPGTALRALPTLVSlhlQDNAVDRLaPGDLagARALRCLYLSGNHITqVSPGALGPAreLEKLH 585
Cdd:PRK15370 306 ---ITHLNVQSNSLTALPETLPPGLKTLEA---GENALTSL-PASL--PPELQVLDVSKNQIT-VLPETLPPT--ITTLD 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 586 LDRNRLREVPtgalEGLP-ALKELQLSGNPLRALPDG----------------AFQPVG-RSLQ--QLFLNSSDLEqiSP 645
Cdd:PRK15370 374 VSRNALTNLP----ENLPaALQIMQASRNNLVRLPESlphfrgegpqptriivEYNPFSeRTIQnmQRLMSSVGYQ--GP 447
|
....*..
gi 568991976 646 RAFSGLG 652
Cdd:PRK15370 448 RVLFAMG 454
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
32-322 |
9.75e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 65.49 E-value: 9.75e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 32 QSPAWHVAAQRCpQTCVCDNSRRhVTCRHQNLTEVPNTIPELTQRLDLQGNILKVLPaaafQDLphltHLDLRNCQVEmv 111
Cdd:PRK15370 161 EAANREEAVQRM-RDCLKNNKTE-LRLKILGLTTIPACIPEQITTLILDNNELKSLP----ENL----QGNIKTLYAN-- 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 112 aegafrglgrllllnlaSNRLSTLPQEALDglgSLRRLELEGNMLEELrPGTFGAlgSLTTLNLAHNALVYLPAMAFQGL 191
Cdd:PRK15370 229 -----------------SNQLTSIPATLPD---TIQEMELSINRITEL-PERLPS--ALQSLDLFHNKISCLPENLPEEL 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 192 lrtRWLQLSHNALSVLaPEALAGlpALRRLSLHHNELQALPgAALSQarSLARLELGHNPLTYTGEEdglALPGLRELAL 271
Cdd:PRK15370 286 ---RYLSVYDNSIRTL-PAHLPS--GITHLNVQSNSLTALP-ETLPP--GLKTLEAGENALTSLPAS---LPPELQVLDV 353
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 568991976 272 DHGSLQALgPRAFAhcPRLHTLDLRGNQLTTLPPlQVPGQLRRLRLQGNPL 322
Cdd:PRK15370 354 SKNQITVL-PETLP--PTITTLDVSRNALTNLPE-NLPAALQIMQASRNNL 400
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
55-232 |
3.23e-09 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 57.87 E-value: 3.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 55 HVTCRHQNLTEVPNTI--PELTQrLDLQGNILKVLPAaaFQDLPHLTHLDLRNcqvemvaegafrglgrllllnlasNRL 132
Cdd:cd21340 6 HLYLNDKNITKIDNLSlcKNLKV-LYLYDNKITKIEN--LEFLTNLTHLYLQN------------------------NQI 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 133 STLpqEALDGLGSLRRLELEGN------------MLEELR---------------PGTFGALG-SLTTLNLAHNALVYLp 184
Cdd:cd21340 59 EKI--ENLENLVNLKKLYLGGNrisvveglenltNLEELHienqrlppgekltfdPRSLAALSnSLRVLNISGNNIDSL- 135
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 568991976 185 aMAFQGLLRTRWLQLSHNALSVLAP--EALAGLPALRRLSLHHNELQALP 232
Cdd:cd21340 136 -EPLAPLRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVCKKP 184
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
685-733 |
1.52e-07 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 48.58 E-value: 1.52e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 568991976 685 NPFHCDCQLLPLHRWLTG---LNLRVGATCATPPSVRGQkVKVAAPVFEACP 733
Cdd:smart00082 1 NPFICDCELRWLLRWLQAnehLQDPVDLRCASPSSLRGP-LLELLHSEFKCP 51
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
674-720 |
6.98e-07 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 53.16 E-value: 6.98e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 568991976 674 LSGLELVDLSGNPFHCDCQLLPLHRWLTGLNLRV----GATCATPPSVRGQ 720
Cdd:TIGR00864 18 LCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVrqpeAALCAGPGALAGQ 68
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
405-439 |
1.81e-04 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 39.22 E-value: 1.81e-04
10 20 30
....*....|....*....|....*....|....*
gi 568991976 405 PCPPACACVAetRHSTCDGRGLQAVPRGFPNDTQL 439
Cdd:smart00013 1 ACPAPCNCSG--TAVDCSGRGLTEVPLDLPPDTTL 33
|
|
| LRR |
smart00370 |
Leucine-rich repeats, outliers; |
602-625 |
2.87e-03 |
|
Leucine-rich repeats, outliers;
Pssm-ID: 197688 [Multi-domain] Cd Length: 24 Bit Score: 35.79 E-value: 2.87e-03
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
43-75 |
3.59e-03 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 35.76 E-value: 3.59e-03
10 20 30
....*....|....*....|....*....|...
gi 568991976 43 CPQTCVCdnSRRHVTCRHQNLTEVPNTIPELTQ 75
Cdd:smart00013 2 CPAPCNC--SGTAVDCSGRGLTEVPLDLPPDTT 32
|
|
| LRRNT |
pfam01462 |
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ... |
405-434 |
4.21e-03 |
|
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.
Pssm-ID: 396168 [Multi-domain] Cd Length: 28 Bit Score: 35.30 E-value: 4.21e-03
10 20 30
....*....|....*....|....*....|
gi 568991976 405 PCPPACACVAetRHSTCDGRGLQAVPRGFP 434
Cdd:pfam01462 1 ACPVPCHCSA--TVVNCSDRGLTAVPRDLP 28
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
67-322 |
7.68e-29 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 120.04 E-value: 7.68e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 67 PNTIPELTQRLDLQGNILKVLPAAAFQDLPHLTHLDLRNCQvemvaegAFRGLGRLLLLNLASNRLSTLPqEALDGLGSL 146
Cdd:COG4886 67 LLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLP-EELANLTNL 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 147 RRLELEGNMLEELrPGTFGALGSLTTLNLAHNALVYLPAmAFQGLLRTRWLQLSHNALSVLaPEALAGLPALRRLSLHHN 226
Cdd:COG4886 139 KELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGN 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 227 ELQALPgAALSQARSLARLELGHNPLTytgeedglALPGLRELaldhgslqalgprafahcPRLHTLDLRGNQLTTLPPL 306
Cdd:COG4886 216 QLTDLP-EPLANLTNLETLDLSNNQLT--------DLPELGNL------------------TNLEELDLSNNQLTDLPPL 268
|
250
....*....|....*.
gi 568991976 307 QVPGQLRRLRLQGNPL 322
Cdd:COG4886 269 ANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
455-687 |
2.62e-28 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 118.50 E-value: 2.62e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 455 FPGLRHLVSLHLQHCGvaelepgALAGLDRLLYLYLSHNQLSGLSAAaLEGAPNLGYLYLEHNRFLRIPgTALRALPTLV 534
Cdd:COG4886 92 LGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEE-LANLTNLKELDLSNNQLTDLP-EPLGNLTNLK 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 535 SLHLQDNAVDRLaPGDLAGARALRCLYLSGNHITQVsPGALGPARELEKLHLDRNRLREVPTgALEGLPALKELQLSGNP 614
Cdd:COG4886 163 SLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQ 239
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568991976 615 LRALPdgafqpvgrSLQQLflnssdleqisprafsglgKGLRSLYLHKNQLQSLPAPLGLSGLELVDLSGNPF 687
Cdd:COG4886 240 LTDLP---------ELGNL-------------------TNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQL 284
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
440-668 |
1.93e-26 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 112.72 E-value: 1.93e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 440 LDLRRNHFPSVPrAAFPGLRHLVSLHLQHCGVAELePGALAGLDRLLYLYLSHNQLSGLSAAaLEGAPNLGYLYLEHNRF 519
Cdd:COG4886 118 LDLSGNQLTDLP-EELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQI 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 520 LRIPgTALRALPTLVSLHLQDNAVDRLaPGDLAGARALRCLYLSGNHITQVSpgALGPARELEKLHLDRNRLREVPTgaL 599
Cdd:COG4886 195 TDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLSNNQLTDLPP--L 268
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568991976 600 EGLPALKELQLSGNPLRALPDGAFQPVGRSLQQLFLNSSDLEQISPRAFSGLGKGLRSLYLHKNQLQSL 668
Cdd:COG4886 269 ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTL 337
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
54-277 |
3.28e-21 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 96.93 E-value: 3.28e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 54 RHVTCRHQNLTEVPNTIPELT--QRLDLQGNILKVLPAAaFQDLPHLTHLDLRNcqvemvaegafrglgrllllnlasNR 131
Cdd:COG4886 139 KELDLSNNQLTDLPEPLGNLTnlKSLDLSNNQLTDLPEE-LGNLTNLKELDLSN------------------------NQ 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 132 LSTLPqEALDGLGSLRRLELEGNMLEELrPGTFGALGSLTTLNLAHNALVYLPAMAfqGLLRTRWLQLSHNALSVLAPea 211
Cdd:COG4886 194 ITDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPELG--NLTNLEELDLSNNQLTDLPP-- 267
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568991976 212 LAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDGLALPGLRELALDHGSLQ 277
Cdd:COG4886 268 LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGL 333
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
418-615 |
2.92e-16 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 78.29 E-value: 2.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 418 HSTCDGRGLQAVP--RGFPNdTQLLDLRRNHFPSVPraAFPGLRHLVSLHLQHCGVAELEPgaLAGLDRLLYLYLSHNQL 495
Cdd:cd21340 6 HLYLNDKNITKIDnlSLCKN-LKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 496 SGLSaaALEGAPNLGYLYLEHNRflripgtalraLPTLVSLHLQDNAVDRLAPgdlagarALRCLYLSGNHITQVSPgaL 575
Cdd:cd21340 81 SVVE--GLENLTNLEELHIENQR-----------LPPGEKLTFDPRSLAALSN-------SLRVLNISGNNIDSLEP--L 138
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 568991976 576 GPARELEKLHLDRNRLREVP--TGALEGLPALKELQLSGNPL 615
Cdd:cd21340 139 APLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPV 180
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
129-541 |
3.12e-14 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 75.36 E-value: 3.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 129 SNRLSTLPQEALDGLGSLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNAlvylpamAFQGLLRTRWLQLSHNALSVLa 208
Cdd:COG4886 57 LRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDL- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 209 PEALAGLPALRRLSLHHNELQALPgAALSQARSLARLELGHNPLTYTGEEDGlALPGLRELALDHGSLQALgPRAFAHCP 288
Cdd:COG4886 129 PEELANLTNLKELDLSNNQLTDLP-EPLGNLTNLKSLDLSNNQLTDLPEELG-NLTNLKELDLSNNQITDL-PEPLGNLT 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 289 RLHTLDLRGNQLTTLP-PLqvpGQLRRLrlqgnplwcacharpllewlvrarvrsdgacrgprrlrgealdtlrpsdlrc 367
Cdd:COG4886 206 NLEELDLSGNQLTDLPePL---ANLTNL---------------------------------------------------- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 368 pgdaaagdgdgdededrpagprapplrsphgeaawatpcppacacvaetrhstcdgrglqavprgfpndtQLLDLRRNHF 447
Cdd:COG4886 231 ----------------------------------------------------------------------ETLDLSNNQL 240
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 448 PSVPraAFPGLRHLVSLHLQHCGVAELEPgaLAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPGTAL 527
Cdd:COG4886 241 TDLP--ELGNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLIL 316
|
410
....*....|....
gi 568991976 528 RALPTLVSLHLQDN 541
Cdd:COG4886 317 LLLLTTLLLLLLLL 330
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
426-639 |
5.09e-13 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 71.89 E-value: 5.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 426 LQAVPRGFPNDTQL--LDLRRNHFPSVPrAAFPGLRHLVSLHLQHCGVAELePGALAGLDRLLYLYLSHNQLSGLSAaaL 503
Cdd:COG4886 171 LTDLPEELGNLTNLkeLDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPE--L 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 504 EGAPNLGYLYLEHNRFLRIPgtALRALPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHITQVSPGALGPARELEK 583
Cdd:COG4886 247 GNLTNLEELDLSNNQLTDLP--PLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLL 324
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 568991976 584 LHLDRNRLREVPTGALEGLPALKELQLSGNPLRALPDGAFQPVGRSLQQLFLNSSD 639
Cdd:COG4886 325 LLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLL 380
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
169-228 |
2.18e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 62.54 E-value: 2.18e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 169 SLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNEL 228
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
459-519 |
2.41e-11 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 59.46 E-value: 2.41e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568991976 459 RHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRF 519
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
426-652 |
6.03e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 65.87 E-value: 6.03e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 426 LQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPgalaglDRLLYLYLSHNQLSGLSAAALEG 505
Cdd:PRK15370 232 LTSIPATLPDTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENLP------EELRYLSVYDNSIRTLPAHLPSG 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 506 apnLGYLYLEHNRFLRIPGTALRALPTLVSlhlQDNAVDRLaPGDLagARALRCLYLSGNHITqVSPGALGPAreLEKLH 585
Cdd:PRK15370 306 ---ITHLNVQSNSLTALPETLPPGLKTLEA---GENALTSL-PASL--PPELQVLDVSKNQIT-VLPETLPPT--ITTLD 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 586 LDRNRLREVPtgalEGLP-ALKELQLSGNPLRALPDG----------------AFQPVG-RSLQ--QLFLNSSDLEqiSP 645
Cdd:PRK15370 374 VSRNALTNLP----ENLPaALQIMQASRNNLVRLPESlphfrgegpqptriivEYNPFSeRTIQnmQRLMSSVGYQ--GP 447
|
....*..
gi 568991976 646 RAFSGLG 652
Cdd:PRK15370 448 RVLFAMG 454
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
32-322 |
9.75e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 65.49 E-value: 9.75e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 32 QSPAWHVAAQRCpQTCVCDNSRRhVTCRHQNLTEVPNTIPELTQRLDLQGNILKVLPaaafQDLphltHLDLRNCQVEmv 111
Cdd:PRK15370 161 EAANREEAVQRM-RDCLKNNKTE-LRLKILGLTTIPACIPEQITTLILDNNELKSLP----ENL----QGNIKTLYAN-- 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 112 aegafrglgrllllnlaSNRLSTLPQEALDglgSLRRLELEGNMLEELrPGTFGAlgSLTTLNLAHNALVYLPAMAFQGL 191
Cdd:PRK15370 229 -----------------SNQLTSIPATLPD---TIQEMELSINRITEL-PERLPS--ALQSLDLFHNKISCLPENLPEEL 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 192 lrtRWLQLSHNALSVLaPEALAGlpALRRLSLHHNELQALPgAALSQarSLARLELGHNPLTYTGEEdglALPGLRELAL 271
Cdd:PRK15370 286 ---RYLSVYDNSIRTL-PAHLPS--GITHLNVQSNSLTALP-ETLPP--GLKTLEAGENALTSLPAS---LPPELQVLDV 353
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 568991976 272 DHGSLQALgPRAFAhcPRLHTLDLRGNQLTTLPPlQVPGQLRRLRLQGNPL 322
Cdd:PRK15370 354 SKNQITVL-PETLP--PTITTLDVSRNALTNLPE-NLPAALQIMQASRNNL 400
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
145-204 |
2.47e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 56.76 E-value: 2.47e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 145 SLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNAL 204
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
54-272 |
7.87e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 61.87 E-value: 7.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 54 RHVTCRHQNLTEVPNTIPELT--QRLDLQGNILKVLPAAaFQDLPHLTHLDLRNcqvemvaegafrglgrllllnlasNR 131
Cdd:COG4886 185 KELDLSNNQITDLPEPLGNLTnlEELDLSGNQLTDLPEP-LANLTNLETLDLSN------------------------NQ 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 132 LSTLPQeaLDGLGSLRRLELEGNMLEELRPgtFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEA 211
Cdd:COG4886 240 LTDLPE--LGNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLI 315
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568991976 212 LAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDGLALPGLRELALD 272
Cdd:COG4886 316 LLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLE 376
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
579-640 |
1.21e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 54.45 E-value: 1.21e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568991976 579 RELEKLHLDRNRLREVPTGALEGLPALKELQLSGNPLRALPDGAFQPVgRSLQQLFLNSSDL 640
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGL-PSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
195-252 |
2.12e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 54.07 E-value: 2.12e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 568991976 195 RWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPL 252
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
55-232 |
3.23e-09 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 57.87 E-value: 3.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 55 HVTCRHQNLTEVPNTI--PELTQrLDLQGNILKVLPAaaFQDLPHLTHLDLRNcqvemvaegafrglgrllllnlasNRL 132
Cdd:cd21340 6 HLYLNDKNITKIDNLSlcKNLKV-LYLYDNKITKIEN--LEFLTNLTHLYLQN------------------------NQI 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 133 STLpqEALDGLGSLRRLELEGN------------MLEELR---------------PGTFGALG-SLTTLNLAHNALVYLp 184
Cdd:cd21340 59 EKI--ENLENLVNLKKLYLGGNrisvveglenltNLEELHienqrlppgekltfdPRSLAALSnSLRVLNISGNNIDSL- 135
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 568991976 185 aMAFQGLLRTRWLQLSHNALSVLAP--EALAGLPALRRLSLHHNELQALP 232
Cdd:cd21340 136 -EPLAPLRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVCKKP 184
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
75-156 |
3.71e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 53.30 E-value: 3.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 75 QRLDLQGNILKVLPAAAFQDLPHLTHLDLRNcqvemvaegafrglgrllllnlasNRLSTLPQEALDGLGSLRRLELEGN 154
Cdd:pfam13855 4 RSLDLSNNRLTSLDDGAFKGLSNLKVLDLSN------------------------NLLTTLSPGAFSGLPSLRYLDLSGN 59
|
..
gi 568991976 155 ML 156
Cdd:pfam13855 60 RL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
555-615 |
6.22e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 52.53 E-value: 6.22e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568991976 555 RALRCLYLSGNHITQVSPGALGPARELEKLHLDRNRLREVPTGALEGLPALKELQLSGNPL 615
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
129-180 |
1.26e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.76 E-value: 1.26e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 568991976 129 SNRLSTLPQEALDGLGSLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNAL 180
Cdd:pfam13855 10 NNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
507-567 |
1.74e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 51.37 E-value: 1.74e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568991976 507 PNLGYLYLEHNRFLRIPGTALRALPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHI 567
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
36-541 |
2.53e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 57.55 E-value: 2.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 36 WHVAAQRCP-QTCVCDNSRRHVTC--RHQNLT-EVPNTIPEL--TQRLDLQGNILK-VLPAAAFQDLPHLTHLDLRNCQV 108
Cdd:PLN00113 51 WNSSADVCLwQGITCNNSSRVVSIdlSGKNISgKISSAIFRLpyIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNF 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 109 EMVAEGAFRGLGRLLLLnlASNRLS-TLPQEaLDGLGSLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNALV-YLPAM 186
Cdd:PLN00113 131 TGSIPRGSIPNLETLDL--SNNMLSgEIPND-IGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVgQIPRE 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 187 AfqGLLRT-RWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLT------------ 253
Cdd:PLN00113 208 L--GQMKSlKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgpippsifslqk 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 254 ----------YTGE--EDGLALPGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQ--LRRLRLQG 319
Cdd:PLN00113 286 lisldlsdnsLSGEipELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHnnLTVLDLST 365
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 320 NPLW-----CACHARPLLEWLVRARV------RSDGACRGPRRLR--GEALDTLRPSDL-RCPGDAAAGDGdgdededrp 385
Cdd:PLN00113 366 NNLTgeipeGLCSSGNLFKLILFSNSlegeipKSLGACRSLRRVRlqDNSFSGELPSEFtKLPLVYFLDIS--------- 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 386 agprAPPLRSPHGEAAWATPcppACACVAETRHSTCDGrglqaVPRGFPNDT-QLLDLRRNHFPSVPRAAFPGLRHLVSL 464
Cdd:PLN00113 437 ----NNNLQGRINSRKWDMP---SLQMLSLARNKFFGG-----LPDSFGSKRlENLDLSRNQFSGAVPRKLGSLSELMQL 504
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568991976 465 HLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFL-RIPgTALRALPTLVSLHLQDN 541
Cdd:PLN00113 505 KLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIP-KNLGNVESLVQVNISHN 581
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
264-322 |
3.13e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.60 E-value: 3.13e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568991976 264 PGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPP--LQVPGQLRRLRLQGNPL 322
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
422-613 |
5.78e-08 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 55.05 E-value: 5.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 422 DGRGLQAVPRGFPNDTQL--LDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGL--------DRLLYLYLS 491
Cdd:cd00116 66 IPRGLQSLLQGLTKGCGLqeLDLSDNALGPDGCGVLESLLRSSSLQELKLNNNGLGDRGLRLLakglkdlpPALEKLVLG 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 492 HNQLSGLSAAALEGapnlgylylehnrflripgtALRALPTLVSLHLQDNAVD-----RLAPGdLAGARALRCLYLSGNH 566
Cdd:cd00116 146 RNRLEGASCEALAK--------------------ALRANRDLKELNLANNGIGdagirALAEG-LKANCNLEVLDLNNNG 204
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 568991976 567 ITQVSPGALGPA----RELEKLHLDRNRLREVPTGAL-----EGLPALKELQLSGN 613
Cdd:cd00116 205 LTDEGASALAETlaslKSLEVLNLGDNNLTDAGAAALasallSPNISLLTLSLSCN 260
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
167-322 |
5.79e-08 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 54.02 E-value: 5.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 167 LGSLTTLNLAHNALVYLPAMAFQGLLRTrwLQLSHNALSVLapEALAGLPALRRLSLHHNELQALPGaaLSQARSLARLE 246
Cdd:cd21340 1 LKRITHLYLNDKNITKIDNLSLCKNLKV--LYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLY 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 247 LGHNPLTytgEEDGLA-LPGLRELALDHGSLQ-----ALGPRA-FAHCPRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQG 319
Cdd:cd21340 75 LGGNRIS---VVEGLEnLTNLEELHIENQRLPpgeklTFDPRSlAALSNSLRVLNISGNNIDSLEPLAPLRNLEQLDASN 151
|
...
gi 568991976 320 NPL 322
Cdd:cd21340 152 NQI 154
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
476-687 |
6.31e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 56.39 E-value: 6.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 476 PGALAGLDRLLYLYLSHNQLSG--------LSA----------------AALEGAPNLGYLYLEHNRFL-RIPGTALrAL 530
Cdd:PLN00113 205 PRELGQMKSLKWIYLGYNNLSGeipyeiggLTSlnhldlvynnltgpipSSLGNLKNLQYLFLYQNKLSgPIPPSIF-SL 283
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 531 PTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHITQVSPGALGPARELEKLHLDRNRLR-EVPTGaLEGLPALKELQ 609
Cdd:PLN00113 284 QKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSgEIPKN-LGKHNNLTVLD 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 610 LSGNPLRA-LPDGAFQPvGRsLQQLFLNSSDLEQISPRAFSGLgKGLRSLYLHKNQLqSLPAPLGLSGLELV---DLSGN 685
Cdd:PLN00113 363 LSTNNLTGeIPEGLCSS-GN-LFKLILFSNSLEGEIPKSLGAC-RSLRRVRLQDNSF-SGELPSEFTKLPLVyflDISNN 438
|
..
gi 568991976 686 PF 687
Cdd:PLN00113 439 NL 440
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
685-733 |
1.52e-07 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 48.58 E-value: 1.52e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 568991976 685 NPFHCDCQLLPLHRWLTG---LNLRVGATCATPPSVRGQkVKVAAPVFEACP 733
Cdd:smart00082 1 NPFICDCELRWLLRWLQAnehLQDPVDLRCASPSSLRGP-LLELLHSEFKCP 51
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
440-495 |
2.12e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 48.29 E-value: 2.12e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 568991976 440 LDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQL 495
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
75-252 |
6.10e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 53.31 E-value: 6.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 75 QRLDLQGNILKVLPAAAFQDLPHLTHLDLRNCQVEMVAEGAFRGLGRLLLLNLASNRLS-TLPQeaLDGLGSLRRLELEG 153
Cdd:PLN00113 407 RRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLSLARNKFFgGLPD--SFGSKRLENLDLSR 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 154 NMLEELRPGTFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPG 233
Cdd:PLN00113 485 NQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIP 564
|
170
....*....|....*....
gi 568991976 234 AALSQARSLARLELGHNPL 252
Cdd:PLN00113 565 KNLGNVESLVQVNISHNHL 583
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
60-226 |
6.24e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 53.16 E-value: 6.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 60 HQNLTEVPNTIPELTQRLDLQGNILKVLPAaafqDLPH-LTHLDLRNCQVEMVAEgafRGLGRLLLLNLASNRLSTLPqE 138
Cdd:PRK15370 271 HNKISCLPENLPEELRYLSVYDNSIRTLPA----HLPSgITHLNVQSNSLTALPE---TLPPGLKTLEAGENALTSLP-A 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 139 ALDglGSLRRLELEGN---MLEELRPGTfgalgsLTTLNLAHNALVYLPAMAFQGLlrtRWLQLSHNALSVLaPEALAGL 215
Cdd:PRK15370 343 SLP--PELQVLDVSKNqitVLPETLPPT------ITTLDVSRNALTNLPENLPAAL---QIMQASRNNLVRL-PESLPHF 410
|
170
....*....|....*
gi 568991976 216 ----PALRRLSLHHN 226
Cdd:PRK15370 411 rgegPQPTRIIVEYN 425
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
531-591 |
6.73e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 46.75 E-value: 6.73e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568991976 531 PTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHITQVSPGALGPARELEKLHLDRNRL 591
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PCC |
TIGR00864 |
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ... |
674-720 |
6.98e-07 |
|
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.
Pssm-ID: 188093 [Multi-domain] Cd Length: 2740 Bit Score: 53.16 E-value: 6.98e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 568991976 674 LSGLELVDLSGNPFHCDCQLLPLHRWLTGLNLRV----GATCATPPSVRGQ 720
Cdd:TIGR00864 18 LCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVrqpeAALCAGPGALAGQ 68
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
490-685 |
8.58e-07 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 52.54 E-value: 8.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 490 LSHNQLSG-LSAAALEGAPNLGYLYLEHNRFL-RIPGTALralPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHI 567
Cdd:PLN00113 100 LSNNQLSGpIPDDIFTTSSSLRYLNLSNNNFTgSIPRGSI---PNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVL 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 568 TQVSPGALGPARELEKLHLDRNRLR-EVPTgALEGLPALKELQLSGNPLRA-LPdgafQPVGR--SLQQLFLNSSDLEQI 643
Cdd:PLN00113 177 VGKIPNSLTNLTSLEFLTLASNQLVgQIPR-ELGQMKSLKWIYLGYNNLSGeIP----YEIGGltSLNHLDLVYNNLTGP 251
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 568991976 644 SPRAFSGLgKGLRSLYLHKNQL--QSLPAPLGLSGLELVDLSGN 685
Cdd:PLN00113 252 IPSSLGNL-KNLQYLFLYQNKLsgPIPPSIFSLQKLISLDLSDN 294
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
138-322 |
1.64e-06 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 49.78 E-value: 1.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 138 EALDGLGSLRRLELEGNMLEELRPgtFGALGSLTTLNLAHNALVYLPAmaFQGLLRTRWLQLSHNALSVLapEALAGLPA 217
Cdd:cd21340 18 DNLSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRISVV--EGLENLTN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 218 LRRLSLHHNELQA------LPGAALSQARSLARLELGHNPLTytgeedglalpglrelaldhgSLQALgprafAHCPRLH 291
Cdd:cd21340 92 LEELHIENQRLPPgekltfDPRSLAALSNSLRVLNISGNNID---------------------SLEPL-----APLRNLE 145
|
170 180 190
....*....|....*....|....*....|....*
gi 568991976 292 TLDLRGNQLTTLPPLQVP----GQLRRLRLQGNPL 322
Cdd:cd21340 146 QLDASNNQISDLEELLDLlsswPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
216-300 |
2.87e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.21 E-value: 2.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 216 PALRRLSLHHNELQALPGAALSQARSLARLELGHNpltytgeedglalpglrelaldhgSLQALGPRAFAHCPRLHTLDL 295
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNN------------------------LLTTLSPGAFSGLPSLRYLDL 56
|
....*
gi 568991976 296 RGNQL 300
Cdd:pfam13855 57 SGNRL 61
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
425-687 |
2.99e-06 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 50.93 E-value: 2.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 425 GLQAVPRGFPNDTQLLDLRRNHFPSVPrAAFPGLRHLVSLHLQHCGVAELEPGalagldrLLYLYLSHNQLSGLSAAAle 504
Cdd:PRK15387 212 GLTTLPDCLPAHITTLVIPDNNLTSLP-ALPPELRTLEVSGNQLTSLPVLPPG-------LLELSIFSNPLTHLPALP-- 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 505 gaPNLGYLYLEHNRFLRIPGTAlralPTLVSLHLQDNAVDRLA--PGDLAGaralrcLYLSGNHITQVSPGALGpareLE 582
Cdd:PRK15387 282 --SGLCKLWIFGNQLTSLPVLP----PGLQELSVSDNQLASLPalPSELCK------LWAYNNQLTSLPTLPSG----LQ 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 583 KLHLDRNRLREVPT------------GALEGLPAL----KELQLSGNPLRALPdgafqPVGRSLQQLFLNSSDLEQISPr 646
Cdd:PRK15387 346 ELSVSDNQLASLPTlpselyklwaynNRLTSLPALpsglKELIVSGNRLTSLP-----VLPSELKELMVSGNRLTSLPM- 419
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 568991976 647 afsgLGKGLRSLYLHKNQLQSLPAPL-GLSGLELVDLSGNPF 687
Cdd:PRK15387 420 ----LPSGLLSLSVYRNQLTRLPESLiHLSSETTVNLEGNPL 457
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
143-519 |
3.38e-06 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 50.62 E-value: 3.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 143 LGSLRRLE---LEGNMLEELRPGTFGALGSLTTLNLAHNALV-YLPAMAFQgLLRTRWLQLSHNALSVLAPEALAGLPAL 218
Cdd:PLN00113 256 LGNLKNLQylfLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSgEIPELVIQ-LQNLEILHLFSNNFTGKIPVALTSLPRL 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 219 RRLSLHHNELQALPGAALSQARSLARLELGHNPLTytGE-EDGLALPG-LRELALDHGSLQALGPRAFAHCPRLHTLDLR 296
Cdd:PLN00113 335 QVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLT--GEiPEGLCSSGnLFKLILFSNSLEGEIPKSLGACRSLRRVRLQ 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 297 GNQLT-TLP------PLQVPGQLRRLRLQGN---PLWcachARPLLEWLVRARVRSDGACrgPRRLRGEALDTLrpsDLr 366
Cdd:PLN00113 413 DNSFSgELPseftklPLVYFLDISNNNLQGRinsRKW----DMPSLQMLSLARNKFFGGL--PDSFGSKRLENL---DL- 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 367 cpgdaaagdgdgdededrpagprapplrsphgeaawatpcppacacvAETRHStcdgrglQAVPRGFPNDTQLLDLR--R 444
Cdd:PLN00113 483 -----------------------------------------------SRNQFS-------GAVPRKLGSLSELMQLKlsE 508
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568991976 445 NHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRF 519
Cdd:PLN00113 509 NKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHL 583
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
484-541 |
3.71e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.82 E-value: 3.71e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 568991976 484 RLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPGTALRALPTLVSLHLQDN 541
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
628-687 |
7.01e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.05 E-value: 7.01e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568991976 628 RSLQQLFLNSSDLEQISPRAFSGLgKGLRSLYLHKNQLQSLP--APLGLSGLELVDLSGNPF 687
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGL-SNLKVLDLSNNLLTTLSpgAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
75-302 |
8.16e-06 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 48.51 E-value: 8.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 75 QRLDLQGNILKVLPAAAFQDL---PHLTHLDLRNCQVE-----MVAEGAfrglgrllllnlasnrlsTLPQEALDGLGSL 146
Cdd:cd00116 84 QELDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLGdrglrLLAKGL------------------KDLPPALEKLVLG 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 147 RRLeLEGNMLEELrPGTFGALGSLTTLNLAHNalvylpamafqgllrtrwlQLSHNALSVLApEALAGLPALRRLSLHHN 226
Cdd:cd00116 146 RNR-LEGASCEAL-AKALRANRDLKELNLANN-------------------GIGDAGIRALA-EGLKANCNLEVLDLNNN 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 227 EL-----QALpGAALSQARSLARLELGHNPLTYTG-----EEDGLALPGLRELALDHGSLQALGPRAFAHC----PRLHT 292
Cdd:cd00116 204 GLtdegaSAL-AETLASLKSLEVLNLGDNNLTDAGaaalaSALLSPNISLLTLSLSCNDITDDGAKDLAEVlaekESLLE 282
|
250
....*....|
gi 568991976 293 LDLRGNQLTT 302
Cdd:cd00116 283 LDLRGNKFGE 292
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
138-329 |
1.83e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.86 E-value: 1.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 138 EALDGLGSLRRLELEGN---------MLEELRPGTfgalgSLTTLNLAHNalvylpamafqgllrtrwlQLSHNALSVLA 208
Cdd:COG5238 230 EALKGNKSLTTLDLSNNqigdegviaLAEALKNNT-----TVETLYLSGN-------------------QIGAEGAIALA 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 209 pEALAGLPALRRLSLHHNELQAlPGA-----ALSQARSLARLELGHNPLTYTGEEdGLA-----LPGLRELALDHGSLQA 278
Cdd:COG5238 286 -KALQGNTTLTSLDLSVNRIGD-EGAialaeGLQGNKTLHTLNLAYNGIGAQGAI-ALAkalqeNTTLHSLDLSDNQIGD 362
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 279 LGPRAFAH----CPRLHTLDLRGNQLT-----TLPPLQVPGQLRRLRLQGNPLWCACHAR 329
Cdd:COG5238 363 EGAIALAKylegNTTLRELNLGKNNIGkqgaeALIDALQTNRLHTLILDGNLIGAEAQQR 422
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
478-606 |
1.94e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.86 E-value: 1.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 478 ALAGLDRLLYLYLSHNQLSGLSAAA----LEGAPNLGYLYLEHN-------RFLripGTALRALPTLVSLHLQDNAVdrl 546
Cdd:COG5238 287 ALQGNTTLTSLDLSVNRIGDEGAIAlaegLQGNKTLHTLNLAYNgigaqgaIAL---AKALQENTTLHSLDLSDNQI--- 360
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568991976 547 apGD---------LAGARALRCLYLSGNHITQVSPGALGPARELEKLH---LDRNRLREVPTGAL-EGLPALK 606
Cdd:COG5238 361 --GDegaialakyLEGNTTLRELNLGKNNIGKQGAEALIDALQTNRLHtliLDGNLIGAEAQQRLeQLLERIK 431
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
460-685 |
2.14e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.48 E-value: 2.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 460 HLVSLHLQHCGVAELEPGALAGLD-RLLYLYLSHNQLS--GLS--AAALEGAPNLGYLYLEHNRF----LRIPGTALRAL 530
Cdd:COG5238 156 VHLLGLAARLGLLAAISMAKALQNnSVETVYLGCNQIGdeGIEelAEALTQNTTVTTLWLKRNPIgdegAEILAEALKGN 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 531 PTLVSLHLQDNAVDrlAPGDLAGARALRC------LYLSGNHITqvSPGALGPARELEK------LHLDRNRLREvpTGA 598
Cdd:COG5238 236 KSLTTLDLSNNQIG--DEGVIALAEALKNnttvetLYLSGNQIG--AEGAIALAKALQGnttltsLDLSVNRIGD--EGA 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 599 ------LEGLPALKELQLSGNPLRAlpDGAfQPVGRSLQQLF-LNSSDLE--QISPRAFSGLGK------GLRSLYLHKN 663
Cdd:COG5238 310 ialaegLQGNKTLHTLNLAYNGIGA--QGA-IALAKALQENTtLHSLDLSdnQIGDEGAIALAKylegntTLRELNLGKN 386
|
250 260
....*....|....*....|....*..
gi 568991976 664 QL-----QSLPAPLGLSGLELVDLSGN 685
Cdd:COG5238 387 NIgkqgaEALIDALQTNRLHTLILDGN 413
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
181-623 |
3.13e-05 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 47.56 E-value: 3.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 181 VYLPAMAFQgllRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDG 260
Cdd:COG3321 861 VPLPTYPFQ---REDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAA 937
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 261 LALPGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQGNPLWCACHARPLLEWLVRARV 340
Cdd:COG3321 938 AAAALLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAA 1017
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 341 RSDGACRGPRRLRGEALDTLRPSDLRcpgdaaagdgdgDEDEDRPAGPRAPPLRSPHGEAAWATPCPPACACVAETRHST 420
Cdd:COG3321 1018 AAALLALAALLAAAAAALAAAAAAAA------------AAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALA 1085
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 421 CDGRGLQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSA 500
Cdd:COG3321 1086 LAAALAAAALALALAALAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAA 1165
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 501 AALEGAPNLGYLYLEHNRFLRIPGTALRALPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHITQVSPGALGPARE 580
Cdd:COG3321 1166 ALLAAAALLLALALALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAV 1245
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 568991976 581 LEKLHLDRNRLREVPTGALEGLPALKELQLSGNPLRALPDGAF 623
Cdd:COG3321 1246 AALAAAAAALLAALAALALLAAAAGLAALAAAAAAAAAALALA 1288
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
458-688 |
6.18e-05 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 46.76 E-value: 6.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 458 LRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFL-RIPGTaLRALPTLVSL 536
Cdd:PLN00113 307 LQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTgEIPEG-LCSSGNLFKL 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 537 HLQDNAVDRLAPGDLAGARALRCLYLSGNHIT----------------QVS----------------------------- 571
Cdd:PLN00113 386 ILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSgelpseftklplvyflDISnnnlqgrinsrkwdmpslqmlslarnkff 465
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 572 ---PGALGpARELEKLHLDRNRLREVPTGALEGLPALKELQLSGNPLRA-LPDGAfqPVGRSLQQLFLNSSDLEQISPRA 647
Cdd:PLN00113 466 gglPDSFG-SKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGeIPDEL--SSCKKLVSLDLSHNQLSGQIPAS 542
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 568991976 648 FSGLgKGLRSLYLHKNQLQ-SLPAPLG-LSGLELVDLSGNPFH 688
Cdd:PLN00113 543 FSEM-PVLSQLDLSQNQLSgEIPKNLGnVESLVQVNISHNHLH 584
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
87-558 |
6.49e-05 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 46.79 E-value: 6.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 87 LPAAAFQdLPHLTHLDLRNCQVEMVAEGAFRGLGRLLLLNLASNRLSTLPQEALDGLGSLRRLELEGNMLEELRPGTFGA 166
Cdd:COG3321 863 LPTYPFQ-REDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAA 941
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 167 LGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLE 246
Cdd:COG3321 942 LLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAAL 1021
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 247 LGHNPLTYTGEEDGLALPGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQGNPLWCAC 326
Cdd:COG3321 1022 LALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAA 1101
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 327 HARPLLEWLVRARVRSDGACRGPRRLRGEALDTLRPSDLRCPGDAAAGDGDGDEDEDRPAGPRAPPLRSPHGEAAWATPC 406
Cdd:COG3321 1102 LAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALAL 1181
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 407 PPACACVAETRHSTcDGRGLQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLL 486
Cdd:COG3321 1182 AAALAAALAGLAAL-LLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALAAAAAALLAALA 1260
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568991976 487 YLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPGTALRALPTLVSLHLQDNAVDRLAPGDLAGARALR 558
Cdd:COG3321 1261 ALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALAA 1332
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
130-322 |
1.15e-04 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 45.54 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 130 NRLSTLPQEALDglgsLRRLELEGNMLEELR---PGtfgalgsLTTLNLAHNALVYLPAMAfQGLLRTRWLQLSHNALSV 206
Cdd:PRK15387 232 NNLTSLPALPPE----LRTLEVSGNQLTSLPvlpPG-------LLELSIFSNPLTHLPALP-SGLCKLWIFGNQLTSLPV 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 207 LAPealaglpALRRLSLHHNELQALPgaalSQARSLARLELGHNPLTytgeedglALP----GLRELALDHGSLQALGP- 281
Cdd:PRK15387 300 LPP-------GLQELSVSDNQLASLP----ALPSELCKLWAYNNQLT--------SLPtlpsGLQELSVSDNQLASLPTl 360
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 568991976 282 -----RAFAHCPRLHTLD----------LRGNQLTTLPPLqvPGQLRRLRLQGNPL 322
Cdd:PRK15387 361 pselyKLWAYNNRLTSLPalpsglkeliVSGNRLTSLPVL--PSELKELMVSGNRL 414
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
485-687 |
1.69e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 45.22 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 485 LLYLYLSHNQLSGLSAAAleGAPNLGYLYLEHNRFL-RIPgTALRALPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLS 563
Cdd:PLN00113 120 LRYLNLSNNNFTGSIPRG--SIPNLETLDLSNNMLSgEIP-NDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLA 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 564 GNHITQVSPGALGPARELEKLHLDRNRLR-EVPTgALEGLPALKELQLSGNPLRALPDGAFQPVgRSLQQLFLNSSDLEQ 642
Cdd:PLN00113 197 SNQLVGQIPRELGQMKSLKWIYLGYNNLSgEIPY-EIGGLTSLNHLDLVYNNLTGPIPSSLGNL-KNLQYLFLYQNKLSG 274
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 568991976 643 ISPRAFSGLGKgLRSLYLHKNQLqSLPAP---LGLSGLELVDLSGNPF 687
Cdd:PLN00113 275 PIPPSIFSLQK-LISLDLSDNSL-SGEIPelvIQLQNLEILHLFSNNF 320
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
405-439 |
1.81e-04 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 39.22 E-value: 1.81e-04
10 20 30
....*....|....*....|....*....|....*
gi 568991976 405 PCPPACACVAetRHSTCDGRGLQAVPRGFPNDTQL 439
Cdd:smart00013 1 ACPAPCNCSG--TAVDCSGRGLTEVPLDLPPDTTL 33
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
140-268 |
3.62e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 44.04 E-value: 3.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991976 140 LDGLGslrrLELEGnmLEELRPGTFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALR 219
Cdd:PLN03150 420 IDGLG----LDNQG--LRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLR 493
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 568991976 220 RLSLHHNELQA-LPGAALSQARSLARLELGHNPltytgeedGL-ALPGLRE 268
Cdd:PLN03150 494 ILNLNGNSLSGrVPAALGGRLLHRASFNFTDNA--------GLcGIPGLRA 536
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
653-686 |
7.53e-04 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 37.61 E-value: 7.53e-04
10 20 30
....*....|....*....|....*....|....
gi 568991976 653 KGLRSLYLHKNQLQSLPAPLGLSGLELVDLSGNP 686
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNN 34
|
|
| LRR |
smart00370 |
Leucine-rich repeats, outliers; |
602-625 |
2.87e-03 |
|
Leucine-rich repeats, outliers;
Pssm-ID: 197688 [Multi-domain] Cd Length: 24 Bit Score: 35.79 E-value: 2.87e-03
|
| LRR_TYP |
smart00369 |
Leucine-rich repeats, typical (most populated) subfamily; |
602-625 |
2.87e-03 |
|
Leucine-rich repeats, typical (most populated) subfamily;
Pssm-ID: 197687 [Multi-domain] Cd Length: 24 Bit Score: 35.79 E-value: 2.87e-03
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
43-75 |
3.59e-03 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 35.76 E-value: 3.59e-03
10 20 30
....*....|....*....|....*....|...
gi 568991976 43 CPQTCVCdnSRRHVTCRHQNLTEVPNTIPELTQ 75
Cdd:smart00013 2 CPAPCNC--SGTAVDCSGRGLTEVPLDLPPDTT 32
|
|
| LRRNT |
pfam01462 |
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence ... |
405-434 |
4.21e-03 |
|
Leucine rich repeat N-terminal domain; Leucine Rich Repeats pfam00560 are short sequence motifs present in a number of proteins with diverse functions and cellular locations. Leucine Rich Repeats are often flanked by cysteine rich domains. This domain is often found at the N-terminus of tandem leucine rich repeats.
Pssm-ID: 396168 [Multi-domain] Cd Length: 28 Bit Score: 35.30 E-value: 4.21e-03
10 20 30
....*....|....*....|....*....|
gi 568991976 405 PCPPACACVAetRHSTCDGRGLQAVPRGFP 434
Cdd:pfam01462 1 ACPVPCHCSA--TVVNCSDRGLTAVPRDLP 28
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
581-615 |
5.05e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 35.30 E-value: 5.05e-03
10 20 30
....*....|....*....|....*....|....*
gi 568991976 581 LEKLHLDRNRLREVPtgALEGLPALKELQLSGNPL 615
Cdd:pfam12799 3 LEVLDLSNNQITDIP--PLAKLPNLETLDLSGNNK 35
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
288-322 |
5.15e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 35.30 E-value: 5.15e-03
10 20 30
....*....|....*....|....*....|....*
gi 568991976 288 PRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQGNPL 322
Cdd:pfam12799 1 PNLEVLDLSNNQITDIPPLAKLPNLETLDLSGNNK 35
|
|
| |
