|
Name |
Accession |
Description |
Interval |
E-value |
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
24-296 |
2.52e-165 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 461.55 E-value: 2.52e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 24 IDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSERRKMVFHITT 103
Cdd:TIGR02238 1 IDKLQAHGINAADIKKLKSAGICTVNGVIMTTRRALCKIKGLSEAKVDKIKEAASKIINPGFITAFEISQKRKKVLKITT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 104 GSQEF------------------EISYWKnSAVSYPLC-------------------------RPDRLRDIADRFNVDHE 140
Cdd:TIGR02238 81 GSQALdgilgggiesmsitevfgEFRCGK-TQLSHTLCvtaqlpremgggngkvayidtegtfRPDRIRAIAERFGVDPD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 141 AVLDNVLYARAYTSEHQMELLDYVAAKFHEEagIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNV 220
Cdd:TIGR02238 160 AVLDNILYARAYTSEHQMELLDYLAAKFSEE--PFRLLIVDSIMALFRVDFSGRGELSERQQKLAQMLSRLNKISEEFNV 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568991289 221 AVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDA 296
Cdd:TIGR02238 238 AVFVTNQVQADPGATMTFIADPKKPIGGHVLAHASTTRILLRKGRGEERVAKLYDSPDMPEAEASFQITEGGIADA 313
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
2-298 |
3.47e-147 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 416.32 E-value: 3.47e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 2 KEDQVVQEESGfqDDEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLI 81
Cdd:PTZ00035 3 ESQNEQQEEEE--EEEAEGFQEIEKLQSAGINAADIKKLKEAGICTVESVAYATKKDLCNIKGISEAKVEKIKEAASKLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 82 EPGFLTAFQYSERRKMVFHITTGSQEF--------------EIsYWKNSAVSYPLC------------------------ 123
Cdd:PTZ00035 81 PMGFISATEYLEARKNIIRITTGSTQLdkllgggietgsitEL-FGEFRTGKTQLChtlcvtcqlpieqgggegkvlyid 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 124 -----RPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGELA 198
Cdd:PTZ00035 160 tegtfRPERIVQIAERFGLDPEDVLDNIAYARAYNHEHQMQLLSQAAAKMAEER--FALLIVDSATALFRVDYSGRGELA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 199 ERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPE 278
Cdd:PTZ00035 238 ERQQHLGKFLRALQKLADEFNVAVVITNQVMADVDGASMFVADPKKPIGGHIIAHASTTRLSLRKGRGEQRICKIYDSPN 317
|
330 340
....*....|....*....|
gi 568991289 279 MPENEATFAITAGGIGDAKE 298
Cdd:PTZ00035 318 LPESEAVFAISEGGIIDAKD 337
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
124-295 |
1.67e-135 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 382.86 E-value: 1.67e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 124 RPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgIFKLLIIDSIMALFRVDFSGRGELAERQQK 203
Cdd:cd19514 66 RPDRIRPIAERFGVDHDAVLDNILYARAYTSEHQMELLDYVAAKFHEEA-VFRLLIIDSIMALFRVDFSGRGELAERQQK 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 204 LAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENE 283
Cdd:cd19514 145 LAQMLSRLQKISEEYNVAVFITNQVTADPGAAMTFQADPKKPIGGHILAHASTTRISLRKGRGEERIAKIYDSPDLPENE 224
|
170
....*....|..
gi 568991289 284 ATFAITAGGIGD 295
Cdd:cd19514 225 ATFAITAGGIAD 236
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
5-298 |
8.50e-127 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 364.87 E-value: 8.50e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 5 QVVQEESGfqDDEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPG 84
Cdd:PLN03187 14 QLVEAEEV--DEEEDLFESIDKLISQGINAGDVKKLQDAGIYTCNGLMMHTKKNLTGIKGLSEAKVDKICEAAEKLLNQG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 85 FLTAFQYSERRKMVFHITTGSQE--------FEISY-------WK--NSAVSYPLC------------------------ 123
Cdd:PLN03187 92 FITGSDALLKRKSVVRITTGSQAldellgggIETRCiteafgeFRsgKTQLAHTLCvttqlptemgggngkvayidtegt 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 124 -RPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGELAERQQ 202
Cdd:PLN03187 172 fRPDRIVPIAERFGMDADAVLDNIIYARAYTYEHQYNLLLGLAAKMAEEP--FRLLIVDSVIALFRVDFTGRGELAERQQ 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 203 KLAQMLSRLQKISEEYNVAVFVTNQMTADPGAtMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPEN 282
Cdd:PLN03187 250 KLAQMLSRLTKIAEEFNVAVYMTNQVIADPGG-GMFISDPKKPAGGHVLAHAATIRLMLRKGKGEQRVCKVFDAPNLPEA 328
|
330
....*....|....*.
gi 568991289 283 EATFAITAGGIGDAKE 298
Cdd:PLN03187 329 EAEFQITSGGIMDAKD 344
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
124-294 |
4.12e-110 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 318.71 E-value: 4.12e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 124 RPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEagIFKLLIIDSIMALFRVDFSGRGELAERQQK 203
Cdd:cd01123 66 RPERLRAIAQRFGLDPDDVLDNVAYARAFNSDHQTQLLDQAAAMMVES--RFKLLIVDSATALYRTDYSGRGELSARQMH 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 204 LAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENE 283
Cdd:cd01123 144 LAKFLRMLQRLADEFGVAVVVTNQVVAQVDGAMMFAADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAE 223
|
170
....*....|.
gi 568991289 284 ATFAITAGGIG 294
Cdd:cd01123 224 AVFAITADGVG 234
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
24-298 |
1.41e-109 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 320.13 E-value: 1.41e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 24 IDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSERRKMVFHITT 103
Cdd:TIGR02239 1 IEKLEGNGITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRQEVIQLTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 104 GSQEF------------------EISYWKnSAVSYPLC-------------------------RPDRLRDIADRFNVDHE 140
Cdd:TIGR02239 81 GSKELdkllgggietgsiteifgEFRTGK-TQLCHTLAvtcqlpidqgggegkalyidtegtfRPERLLAIAERYGLNPE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 141 AVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNV 220
Cdd:TIGR02239 160 DVLDNVAYARAYNTDHQLQLLQQAAAMMSESR--FALLIVDSATALYRTDFSGRGELSARQMHLARFLRSLQRLADEFGV 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568991289 221 AVFVTNQMTADP-GATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE 298
Cdd:TIGR02239 238 AVVITNQVVAQVdGAGSMFAGDPKKPIGGNIMAHASTTRLSLRKGRGEQRICKIYDSPCLPESEAMFAIYEDGIGDPKE 316
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
24-298 |
5.95e-107 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 314.36 E-value: 5.95e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 24 IDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSERRKMVFHITT 103
Cdd:PLN03186 28 IEQLQASGIAALDIKKLKDAGIHTVESLAYAPKKDLLQIKGISEAKVEKILEAASKLVPLGFTTASQLHAQRQEIIQITT 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 104 GSQEF--------------EIsYWKNSAVSYPLC-----------------------------RPDRLRDIADRFNVDHE 140
Cdd:PLN03186 108 GSRELdkileggietgsitEI-YGEFRTGKTQLChtlcvtcqlpldqgggegkamyidtegtfRPQRLIQIAERFGLNGA 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 141 AVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNV 220
Cdd:PLN03186 187 DVLENVAYARAYNTDHQSELLLEAASMMAETR--FALMIVDSATALYRTEFSGRGELSARQMHLGKFLRSLQRLADEFGV 264
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568991289 221 AVFVTNQMTADPGAtMTFQADPK-KPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE 298
Cdd:PLN03186 265 AVVITNQVVAQVDG-SAFFAGPQlKPIGGNIMAHASTTRLALRKGRGENRICKVISSPCLPEAEARFSISSEGVTDVKD 342
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
84-296 |
3.04e-104 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 304.61 E-value: 3.04e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 84 GFLTAFQYSERRKMVFHITTGSQEF--------------EI---SYWKNSAVSYPLC----------------------- 123
Cdd:pfam08423 2 GFTTATELHQRRSELIQITTGSKELdkllgggietgsitEIfgeFRTGKTQLCHTLCvtcqlplemgggegkalyidteg 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 124 --RPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGELAERQ 201
Cdd:pfam08423 82 tfRPERLVAIAERYGLDPEDVLDNVAYARAYNSEHQMQLLQQAAAMMSESR--FALLIVDSATALYRTDFSGRGELAERQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 202 QKLAQMLSRLQKISEEYNVAVFVTNQMTADP-GATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMP 280
Cdd:pfam08423 160 QHLAKFLRTLQRLADEFGVAVVITNQVVAQVdGAAGMFSGDPKKPIGGHIMAHASTTRLSLRKGRGEQRICKIYDSPCLP 239
|
250
....*....|....*.
gi 568991289 281 ENEATFAITAGGIGDA 296
Cdd:pfam08423 240 ESEAVFAIGSGGIIDP 255
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
124-295 |
1.21e-92 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 274.20 E-value: 1.21e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 124 RPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAgiFKLLIIDSIMALFRVDFSGRGELAERQQK 203
Cdd:cd19513 66 RPERLLAIAERYGLNGEDVLDNVAYARAYNTDHQMQLLIQASAMMAESR--YALLIVDSATALYRTDYSGRGELSARQMH 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 204 LAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENE 283
Cdd:cd19513 144 LAKFLRMLQRLADEFGVAVVITNQVVAQVDGAAMFAGDPKKPIGGNIMAHASTTRLYLRKGRGETRICKIYDSPCLPEAE 223
|
170
....*....|..
gi 568991289 284 ATFAITAGGIGD 295
Cdd:cd19513 224 AVFAITEDGIGD 235
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
23-296 |
1.14e-80 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 246.71 E-value: 1.14e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 23 DIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIE-PGFLTAFQYSERRKMVFHI 101
Cdd:PRK04301 5 EKDLEDLPGVGPATAEKLREAGYDTVEAIAVASPKELSEAAGIGESTAAKIIEAAREAADiGGFETALEVLERRKNVGKI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 102 TTGSQEF------------------EISYWKnSAVSYPLC-------------------------RPDRLRDIADRFNVD 138
Cdd:PRK04301 85 TTGSKELdellgggietqsitefygEFGSGK-TQICHQLAvnvqlpeekgglegkavyidtegtfRPERIEQMAEALGLD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 139 HEAVLDNVLYARAYTSEHQMELLDYvAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEY 218
Cdd:PRK04301 164 PDEVLDNIHVARAYNSDHQMLLAEK-AEELIKEGENIKLVIVDSLTAHFRAEYVGRGNLAERQQKLNKHLHDLLRLADLY 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568991289 219 NVAVFVTNQMTADPGAtmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDA 296
Cdd:PRK04301 243 NAAVVVTNQVMARPDA---FFGDPTQPIGGHILGHTATFRIYLRKSKGNKRIARLVDSPHLPEGEAVFRITEEGIRDA 317
|
|
| recomb_radA |
TIGR02236 |
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
31-295 |
1.11e-75 |
|
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 233.87 E-value: 1.11e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 31 GINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPG-FLTAFQYSERRKMVFHITTGSQEF- 108
Cdd:TIGR02236 6 GVGPATAEKLREAGYDTFEAIAVASPKELSEIAGISEGTAAKIIQAARKAADLGgFETADDVLERRKTIGKITTGSKELd 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 109 -----------------EISYWKnSAVSYPLC-------------------------RPDRLRDIADRFNVDHEAVLDNV 146
Cdd:TIGR02236 86 ellgggietqaitevfgEFGSGK-TQICHQLAvnvqlpeekgglggkavyidtentfRPERIMQMAEARGLDPDEVLKNI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 147 LYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTN 226
Cdd:TIGR02236 165 YVARAYNSNHQMLLVEKAEDLIKELNNPVKLLIVDSLTSHFRAEYVGRGALAERQQKLNKHLHDLLRLADLYNAAVVVTN 244
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568991289 227 QMTADPGAtmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGD 295
Cdd:TIGR02236 245 QVMARPDA---FFGDPTRPIGGHILGHAATFRVYLRKGKGDKRIARLVDSPHLPEGEAVFRITEKGIED 310
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
124-295 |
6.33e-68 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 211.07 E-value: 6.33e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 124 RPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIfKLLIIDSIMALFRVDFSGRGELAERQQK 203
Cdd:cd19515 66 RPERIMQMAKALGLDPDEVLDNIYVARAYNSNHQMLLVEKAEDLIKEGNNI-KLLIVDSLTSHFRAEYVGRGTLAERQQK 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 204 LAQMLSRLQKISEEYNVAVFVTNQMTADPGAtmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENE 283
Cdd:cd19515 145 LNKHLHDLHRLADLYNIAVLVTNQVMAKPDA---FFGDPTQAIGGHILGHAATFRVYLRKGKGGKRIARLVDSPHLPEGE 221
|
170
....*....|..
gi 568991289 284 ATFAITAGGIGD 295
Cdd:cd19515 222 AVFRITEKGIED 233
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
123-263 |
1.71e-29 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 110.52 E-value: 1.71e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 123 CRPDRLRDIA---DRFNVDHEAVLDNVLYARAYTSEHQMELLDYvaakfHEEAGI----FKLLIIDSIMALFRVDF---- 191
Cdd:cd01393 41 FPPSRLVQILeasPSSELELAEALSRLLYFRPPDTLAHLLALDS-----LPESLFpppnTSLVVVDSVSALFRKAFprgg 115
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568991289 192 SGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGAtmTFQADPKKPIGGHILAHASTTRISLRK 263
Cdd:cd01393 116 DGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTTKIRG--GSGASLVPPALGNTWEHSVSTRLLLYR 185
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
125-293 |
2.67e-23 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 95.31 E-value: 2.67e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 125 PDRLRDIADRfnvDHEAVLDNVLYARAYTSEHQ----MELLDYVAAKFheeagifKLLIIDSIMALFRVDFSGRGELAER 200
Cdd:PRK09361 64 PERFKQIAGE---DFEELLSNIIIFEPSSFEEQseaiRKAEKLAKENV-------GLIVLDSATSLYRLELEDEEDNSKL 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 201 QQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTfqadpkKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMP 280
Cdd:PRK09361 134 NRELGRQLTHLLKLARKHDLAVVITNQVYSDIDSDGL------RPLGGHTLEHWSKTILRLEKFRNGKRRATLEKHRSRP 207
|
170
....*....|....
gi 568991289 281 ENE-ATFAITAGGI 293
Cdd:PRK09361 208 EGEsAEFRITDRGI 221
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
125-293 |
3.69e-20 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 86.60 E-value: 3.69e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 125 PDRLRDIA-DRFnvdhEAVLDNVLYARAYTSEHQMELLDYvAAKFhEEAGIFKLLIIDSIMALFRVDfsgRGELAERQQK 203
Cdd:cd01394 60 PERFQQIAgERF----ESIASNIIVFEPYSFDEQGVAIQE-AEKL-LKSDKVDLVVVDSATALYRLE---LGDDSEANRE 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 204 LAQMLSRLQKISEEYNVAVFVTNQMTADpgatmtFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPEMPENE 283
Cdd:cd01394 131 LSRQMSKLLSIARKYDIPVVITNQVYSD------IDDDRLKPVGGTLLEHWSKAIIRLEKSPPGLRRATLEKHRSRPEGQ 204
|
170
....*....|.
gi 568991289 284 -ATFAITAGGI 293
Cdd:cd01394 205 sAGFRITDRGI 215
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
127-263 |
6.33e-20 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 86.58 E-value: 6.33e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 127 RLRDIADRF-----NVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIfKLLIIDSIMALFRVDF-SGRGELAER 200
Cdd:cd19491 62 RLQQLASSLpkryhLEKAKNFLDNIFVEHVADLETLEHCLNYQLPALLERGPI-RLVVIDSIAALFRSEFdTSRSDLVER 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 201 QQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGA---------------TMTFQADP----KKPIGGHILAHASTTRISL 261
Cdd:cd19491 141 AKYLRRLADHLKRLADKYNLAVVVVNQVTDRFDSssdasglgvldylsqFSSFSGGVsgnrKVPALGLTWANLVNTRLML 220
|
..
gi 568991289 262 RK 263
Cdd:cd19491 221 SR 222
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
119-277 |
4.66e-18 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 80.83 E-value: 4.66e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 119 SYPLCRPDRLRDIADRFNVDHEAVLDNVLyaraytsEHQMELLDYVAAKfheeaGIfKLLIIDSIMALFRVDFSG-RGEL 197
Cdd:cd19493 75 SGFMEENERAEEMLKRVAVVRVTTLAQLL-------ERLPNLEEHILSS-----GV-RLVVIDSIAALVRREFGGsDGEV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 198 AERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIgGHILAHASTTRISLRKGRG-ELRIAKIYDS 276
Cdd:cd19493 142 TERHNALAREASSLKRLAEEFRIAVLVTNQATTHFGDAGDGSSGVTAAL-GDAWAHAVNTRLRLERCLLqLRRVLEIVKS 220
|
.
gi 568991289 277 P 277
Cdd:cd19493 221 P 221
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
145-277 |
3.52e-15 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 71.87 E-value: 3.52e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 145 NVLYARAYTSEHQMELLDYVAAKFHEEAGIfKLLIIDSIMALFRVDFSGrgeLAERQQKLAQMLSRLQKISEEYNVAVFV 224
Cdd:cd19492 48 NIHYFRVHDYVELLALINSLPKFLEDHPKV-KLIVVDSIAFPFRHDFDD---LAQRTRLLNGLAQLLHSLARQHNLAVVL 123
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 568991289 225 TNQMTADPGATMTFQAdpkKPIGGHILAHASTTRISLRKGRGElRIAKIYDSP 277
Cdd:cd19492 124 TNQVTTKISEDGQSQL---VPALGESWSHACTTRLFLTWDEKQ-RFAHLYKSP 172
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
132-264 |
1.15e-10 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 61.34 E-value: 1.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 132 ADRFNVDheavLDNVLYARAYTSEHQMELLDYVAakfheEAGIFKLLIIDSIMALF-RVDFSGR---GELAERQQKLAQM 207
Cdd:COG0468 108 AKKLGVD----IDNLLVSQPDTGEQALEIAETLV-----RSGAVDLIVVDSVAALVpKAEIEGEmgdSHVGLQARLMSQA 178
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 568991289 208 LSRLQKISEEYNVAVFVTNQMTADPGatMTFqADPKKPIGGHILAHASTTRISLRKG 264
Cdd:COG0468 179 LRKLTGAISKSNTTVIFINQLREKIG--VMF-GNPETTTGGNALKFYASVRLDIRRI 232
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
125-263 |
4.32e-08 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 52.64 E-value: 4.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 125 PDRLRDIAD-RFNVDHE--AVLDNVLYARAYTSEHQMELLDYVAAKFHEE----AGIFKLLIIDSIMALFRVDFSGrgel 197
Cdd:cd19489 50 ARRLAQILKsRAQDAEEidKALQRIRVVRVFDPYELLDLLEELRNTLSQQqenlYSRLKLVIIDSLSALISPLLGG---- 125
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568991289 198 AERQQKLAQM--LSR-LQKISEEYNVAVFVTNQMTADPGatMTFQADPkKPIGGHILAHASTTRISLRK 263
Cdd:cd19489 126 SKHSEGHALLasLARlLKKLAAEYQIAVLVTNLTVRGGD--GGQQGST-KPALGEYWESVPSTRLLLSR 191
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
137-263 |
5.47e-06 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 46.57 E-value: 5.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 137 VDHEAV----LDNVLYARAYTSEH---QMELLDYVAAK--FHEEAGifkLLIIDSIMALFRVDFSGRGELAERQQK---- 203
Cdd:cd19490 79 EDVEEIarecLQRLHIFRCHSSLQllaTLLSLENYLLSlsANPELG---LLLIDSISAFYWQDRFSAELARAAPLLqeaa 155
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568991289 204 LAQMLSRLQKISEEYNVAVFVTNQM-----------TADPGATMTFQADPKKPIGGHILAHASTTRISLRK 263
Cdd:cd19490 156 LRAILRELRRLRRRFQLVVIATKQAlfpgksastdnPAANNAVSKASAPSHREYLPRPWQRLVTHRLVLSR 226
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
124-293 |
8.67e-05 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 42.98 E-value: 8.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 124 RPDRLRDIADRFNVDHEAVLDN--VLYARAYTSEHQM---ELLDYVAAKFHEEAGifKLLIIDSIMALFRvdfsgrgeLA 198
Cdd:COG0467 59 SPEQLLRRAESLGLDLEEYIESglLRIIDLSPEELGLdleELLARLREAVEEFGA--KRVVIDSLSGLLL--------AL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568991289 199 ERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGatmtfqadpkkPIGGHILAHASTTRISLRK--GRGE----LRIAK 272
Cdd:COG0467 129 PDPERLREFLHRLLRYLKKRGVTTLLTSETGGLED-----------EATEGGLSYLADGVILLRYveLGGElrraLSVLK 197
|
170 180
....*....|....*....|.
gi 568991289 273 IYDSPeMPENEATFAITAGGI 293
Cdd:COG0467 198 MRGSA-HDRTIREFEITDGGI 217
|
|
| HHH_5 |
pfam14520 |
Helix-hairpin-helix domain; |
25-79 |
1.18e-04 |
|
Helix-hairpin-helix domain;
Pssm-ID: 434010 [Multi-domain] Cd Length: 57 Bit Score: 39.39 E-value: 1.18e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 568991289 25 DLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANK 79
Cdd:pfam14520 3 ELLSISGIGPKTALALLSAGIGTVEDLAEADVDELAEIPGIGEKTAQRIILELRD 57
|
|
| |
