|
Name |
Accession |
Description |
Interval |
E-value |
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
150-938 |
0e+00 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 1143.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 150 LQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQlldarrtkHL 229
Cdd:pfam10174 1 LQAQLRDLQRENELLRRELDIKESKLGSSMNSIKTFWSPELKKERALRKEEAARISVLKEQYRVTQEENQ--------HL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 230 QLTIQALQDELRTQRDLNHLLQQE---SGNRGAEHF-TIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQT 305
Cdd:pfam10174 73 QLTIQALQDELRAQRDLNQLLQQDfttSPVDGEDKFsTPELTEENFRRLQSEHERQAKELFLLRKTLEEMELRIETQKQT 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 306 LNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQ 385
Cdd:pfam10174 153 LGARDESIKKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDPAKTKALQ 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 386 TVIEMKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKL 465
Cdd:pfam10174 233 TVIEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESELLALQTKL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 466 ETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVK 545
Cdd:pfam10174 313 ETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVK 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 546 ERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIES 625
Cdd:pfam10174 393 ERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQREREDRERLEELES 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 626 FRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKqaeqlfnqmy 705
Cdd:pfam10174 473 LKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKK---------- 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 706 npAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKV 785
Cdd:pfam10174 543 --AHNAEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKV 620
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 786 ANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERR 865
Cdd:pfam10174 621 ANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELDATKARLSSTQQSLAEKDGHLTNLRAERR 700
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568987518 866 KQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQqvgrparQTQNRMKL 938
Cdd:pfam10174 701 KQLEEILEMKQEALLAAISEKDANIALLELSSSKKKKTQEEVMALKREKDRLVHQLKQ-------QTQNRMKL 766
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
446-924 |
6.47e-18 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 89.61 E-value: 6.47e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 446 QLKQELSKKESELLALqtKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT 525
Cdd:COG1196 217 ELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 526 EEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERII 605
Cdd:COG1196 295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 606 ERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEE 685
Cdd:COG1196 375 AEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 686 CNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYY-RDECGKAQAEVDRLLEILKEVENEKNDKD 764
Cdd:COG1196 455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgFLEGVKAALLLAGLRGLAGAVAVLIGVEA 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 765 KKIAELE-SLTLRHMKDQNKKVANLKYNQQLEKKKNAQ----LLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDAT 839
Cdd:COG1196 535 AYEAALEaALAAALQNIVVEDDEVAAAAIEYLKAAKAGratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADAR 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 840 KARLASTQQSLAEKEAHLANLRIERRK----QLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD 915
Cdd:COG1196 615 YYVLGDTLLGRTLVAARLEAALRRAVTlagrLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694
|
....*....
gi 568987518 916 RLVHQLKQQ 924
Cdd:COG1196 695 LEEALLAEE 703
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
441-946 |
2.15e-17 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 87.68 E-value: 2.15e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 441 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 520
Cdd:COG1196 252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEE 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 521 LQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSE 600
Cdd:COG1196 332 LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 601 KERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIE 680
Cdd:COG1196 412 LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 681 QKkeecnKLEAQLKKQAEQlFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKA-QAEVDRLLEILKEVENE 759
Cdd:COG1196 492 RL-----LLLLEAEADYEG-FLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAlQNIVVEDDEVAAAAIEY 565
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 760 knDKDKKIAELESLTLRHMKDQNKKVANLKYNQQLEKkknAQLLEEVRRREDSMVDNSQHLQIEELMNA--LEKTRQELD 837
Cdd:COG1196 566 --LKAAKAGRATFLPLDKIRARAALAAALARGAIGAA---VDLVASDLREADARYYVLGDTLLGRTLVAarLEAALRRAV 640
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 838 ATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLE--LSASKKKKTQEEVMALKREKD 915
Cdd:COG1196 641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEalLAEEEEERELAEAEEERLEEE 720
|
490 500 510
....*....|....*....|....*....|.
gi 568987518 916 RLVHQLKQQVGRPARQTQNRMKLMADNYDED 946
Cdd:COG1196 721 LEEEALEEQLEAEREELLEELLEEEELLEEE 751
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
441-700 |
4.67e-17 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 86.66 E-value: 4.67e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 441 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 520
Cdd:TIGR02169 673 PAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 521 LQDLTEEKGTLAGEIRDMKDMLEVKERKINVL-----QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLE 595
Cdd:TIGR02169 753 IENVKSELKELEARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLE 832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 596 EALSEKERIIERLKEQRErddrERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSL 675
Cdd:TIGR02169 833 KEIQELQEQRIDLKEQIK----SIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL 908
|
250 260
....*....|....*....|....*
gi 568987518 676 EIAIEQKKEECNKLEAQLKKQAEQL 700
Cdd:TIGR02169 909 EAQIEKKRKRLSELKAKLEALEEEL 933
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
191-913 |
7.98e-17 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 85.89 E-value: 7.98e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 191 KKERVLRKEEAARMSVLKEQMRVSHEENQLLDARRTKHLQLTIQALQDELRTQRDLNHLLQQESgnrgaehftielTEEN 270
Cdd:TIGR02169 171 KKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEA------------LERQ 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 271 FRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEmlqskglpskslEDDNERTRRMAEAESQVSHL 350
Cdd:TIGR02169 239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE------------EEQLRVKEKIGELEAEIASL 306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 351 EVILDQKEKEnihLREELHRRSQLQPEPAKTKAlqtVIEMKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQI 430
Cdd:TIGR02169 307 ERSIAEKERE---LEDAEERLAKLEAEIDKLLA---EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 431 EVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAkeqraaiLQTEVDALRLRLEEK 510
Cdd:TIGR02169 381 AETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINE-------LEEEKEDKALEIKKQ 453
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 511 ESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSL-----QTDSS 585
Cdd:TIGR02169 454 EWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtvaQLGSV 533
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 586 NTDTALAtLEEALSEK------------ERIIERLKEQR-----------------------------------ERDDRE 618
Cdd:TIGR02169 534 GERYATA-IEVAAGNRlnnvvveddavaKEAIELLKRRKagratflplnkmrderrdlsilsedgvigfavdlvEFDPKY 612
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 619 R------------LEEIESFRK---------------------------------ENKDLKEKVNALQAELTEKE---SS 650
Cdd:TIGR02169 613 EpafkyvfgdtlvVEDIEAARRlmgkyrmvtlegelfeksgamtggsraprggilFSRSEPAELQRLRERLEGLKrelSS 692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 651 LIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDK 730
Cdd:TIGR02169 693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEE 772
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 731 EASYYRDECGKAQAEVDRllEILKEVENEKNDKDKKIAELESLTlrhmKDQNKKVANLKYNQQLEKKKNAQLLEEVRRRE 810
Cdd:TIGR02169 773 DLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARL----REIEQKLNRLTLEKEYLEKEIQELQEQRIDLK 846
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 811 DSMVDNSQhlQIEELMNALEKTRQELDATKARLAstqqSLAEKEAHLANLRIERRKQLEEiLEMKQEALLAAISEKDANI 890
Cdd:TIGR02169 847 EQIKSIEK--EIENLNGKKEELEEELEELEAALR----DLESRLGDLKKERDELEAQLRE-LERKIEELEAQIEKKRKRL 919
|
810 820
....*....|....*....|...
gi 568987518 891 ALLELSASKKKKTQEEVMALKRE 913
Cdd:TIGR02169 920 SELKAKLEALEEELSEIEDPKGE 942
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
371-925 |
8.34e-17 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 85.46 E-value: 8.34e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 371 RSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQE 450
Cdd:TIGR04523 46 KNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVE 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 451 LSKKE--------------SELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALR---LRLEEKESF 513
Cdd:TIGR04523 126 LNKLEkqkkenkknidkflTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKnklLKLELLLSN 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 514 LNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALAT 593
Cdd:TIGR04523 206 LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKE 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 594 LEEALSEKERIIERLKEQRERDdrerleEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLK 673
Cdd:TIGR04523 286 LEKQLNQLKSEISDLNNQKEQD------WNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENS 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 674 SLEIAIEQKKEECNKLE---AQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLL 750
Cdd:TIGR04523 360 EKQRELEEKQNEIEKLKkenQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNN 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 751 EILKEVENEKNDKDKKIAELESLTlrhmKDQNKKVANLKYnqqlEKKKNAQLLEEVRRREDSmvDNSQHLQIEELMNALE 830
Cdd:TIGR04523 440 SEIKDLTNQDSVKELIIKNLDNTR----ESLETQLKVLSR----SINKIKQNLEQKQKELKS--KEKELKKLNEEKKELE 509
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 831 KTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEI-LEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMA 909
Cdd:TIGR04523 510 EKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDdFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQE 589
|
570
....*....|....*.
gi 568987518 910 LKREKDRLVHQLKQQV 925
Cdd:TIGR04523 590 LIDQKEKEKKDLIKEI 605
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
389-917 |
4.88e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 83.45 E-value: 4.88e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 389 EMKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVykshskfMKTKIDQLKQELSKKESELLALQTKLETL 468
Cdd:COG1196 221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAE-------LEAELEELRLELEELELELEEAQAEEYEL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 469 SNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERK 548
Cdd:COG1196 294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 549 INVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRE---RDDRERLEEIES 625
Cdd:COG1196 374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEeeeEALEEAAEEEAE 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 626 FRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLAS---------------------AGLKRDSKLKSLEIAIEQKKE 684
Cdd:COG1196 454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAArllllleaeadyegflegvkaALLLAGLRGLAGAVAVLIGVE 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 685 EC-----------------NKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQ---LDKEASYYRDECGKAQA 744
Cdd:COG1196 534 AAyeaaleaalaaalqnivVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALArgaIGAAVDLVASDLREADA 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 745 EVDRLLEILKEVENEKNDKDKKIAELESL-TLRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIE 823
Cdd:COG1196 614 RYYVLGDTLLGRTLVAARLEAALRRAVTLaGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 824 ELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELsaskkkkt 903
Cdd:COG1196 694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL-------- 765
|
570
....*....|....
gi 568987518 904 QEEVMALKREKDRL 917
Cdd:COG1196 766 ERELERLEREIEAL 779
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
421-917 |
1.74e-15 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 81.65 E-value: 1.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 421 EDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQnsdcKQHIEVLKESLTAKEQRAAILQTEV 500
Cdd:PRK03918 179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKE----VKELEELKEEIEELEKELESLEGSK 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 501 DALRLRLEEKESFLNKKTKQLQDLTE---------EKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLT 571
Cdd:PRK03918 255 RKLEEKIRELEERIEELKKEIEELEEkvkelkelkEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 572 NLKDRVKSLQTDSSNTDTALATLEEALSEKERI------IERLKEQRERDDRERLE-EIESFRKENKDLKEKVNALQAEL 644
Cdd:PRK03918 335 EKEERLEELKKKLKELEKRLEELEERHELYEEAkakkeeLERLKKRLTGLTPEKLEkELEELEKAKEEIEEEISKITARI 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 645 TEKESSLIDLKEHASSLASAG-------------------------LKRDSK-LKSLEIAIEQKKEECNKLEAQLKKQAE 698
Cdd:PRK03918 415 GELKKEIKELKKAIEELKKAKgkcpvcgrelteehrkelleeytaeLKRIEKeLKEIEEKERKLRKELRELEKVLKKESE 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 699 QLFN-QMYNPAHNIEddSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRL---LEILKEVENEKNDKDKKIAELEslt 774
Cdd:PRK03918 495 LIKLkELAEQLKELE--EKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLkkeLEKLEELKKKLAELEKKLDELE--- 569
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 775 lRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEElmNALEKTRQELDATKARLASTQQSLAEKE 854
Cdd:PRK03918 570 -EELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREE--KELKKLEEELDKAFEELAETEKRLEELR 646
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568987518 855 AHLANLRI----ERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRL 917
Cdd:PRK03918 647 KELEELEKkyseEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKEL 713
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
140-772 |
2.14e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 81.26 E-value: 2.14e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 140 RQVRDSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIK--TFWSPELKKERVLRKEEAARMSVLKEQMRVSHEE 217
Cdd:TIGR02168 276 VSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEelEAQLEELESKLDELAEELAELEEKLEELKEELES 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 218 -NQLLDARRTK--HLQLTIQALQDELRTQR-DLNHLLQQESGNRGaehfTIELTEENFRRLQAEHDRQAKELFLLRKTLE 293
Cdd:TIGR02168 356 lEAELEELEAEleELESRLEELEEQLETLRsKVAQLELQIASLNN----EIERLEARLERLEDRRERLQQEIEELLKKLE 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 294 EMELriETQKQTLNARDESIKKLLEMLQS--------KGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLR 365
Cdd:TIGR02168 432 EAEL--KELQAELEELEEELEELQEELERleealeelREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 366 EELHRRSQL-----------QPEPAKTKALQTVIE------------------------------------MKDTKIASL 398
Cdd:TIGR02168 510 ALLKNQSGLsgilgvlseliSVDEGYEAAIEAALGgrlqavvvenlnaakkaiaflkqnelgrvtflpldsIKGTEIQGN 589
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 399 ERNIRDLEDEVQMLKAN-----------------GVLNTEDREEEIKQIEVYKSHSKFM--------------------- 440
Cdd:TIGR02168 590 DREILKNIEGFLGVAKDlvkfdpklrkalsyllgGVLVVDDLDNALELAKKLRPGYRIVtldgdlvrpggvitggsaktn 669
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 441 ------KTKIDQLKQELSKKESELLALQTKLETLSNQNSDckqhievLKESLTAKEQRAAILQTEVDALRLRLEEKESFL 514
Cdd:TIGR02168 670 ssilerRREIEELEEKIEELEEKIAELEKALAELRKELEE-------LEEELEQLRKELEELSRQISALRKDLARLEAEV 742
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 515 NKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATL 594
Cdd:TIGR02168 743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 595 EEALSEKERIIERLKEQRERDD---RERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSK 671
Cdd:TIGR02168 823 RERLESLERRIAATERRLEDLEeqiEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 672 LKSLE---IAIEQKKEECNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQ-LDKEASYYRDECGKAQAEVD 747
Cdd:TIGR02168 903 LRELEskrSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENkIEDDEEEARRRLKRLENKIK 982
|
730 740 750
....*....|....*....|....*....|..
gi 568987518 748 RL-------LEILKEVENEKNDKDKKIAELES 772
Cdd:TIGR02168 983 ELgpvnlaaIEEYEELKERYDFLTAQKEDLTE 1014
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
258-939 |
1.49e-14 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 78.62 E-value: 1.49e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 258 GAEHFTIELTEENF------RRLQAEHDRQAKELFLLRKT-------LEEMEL---------RIETQKQTlNARDESIKK 315
Cdd:pfam15921 72 GKEHIERVLEEYSHqvkdlqRRLNESNELHEKQKFYLRQSvidlqtkLQEMQMerdamadirRRESQSQE-DLRNQLQNT 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 316 LLEMLQSKGLPSKSLEDDN---ERTRRMAEAESQVSH--LEVILDQKEKENIHLREelHRRSQLQPEPAKTKALQTVIEM 390
Cdd:pfam15921 151 VHELEAAKCLKEDMLEDSNtqiEQLRKMMLSHEGVLQeiRSILVDFEEASGKKIYE--HDSMSTMHFRSLGSAISKILRE 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 391 KDTKIASLERNIRDLEDEVQMLKAngvlntedreEEIKQIEVykshskFMKTKIDQLKQELSKKESELLALQTKLETLSN 470
Cdd:pfam15921 229 LDTEISYLKGRIFPVEDQLEALKS----------ESQNKIEL------LLQQHQDRIEQLISEHEVEITGLTEKASSARS 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 471 QNSDCKQHIEVLKESltAKEQRAAILqtevdalrlrleekesflnkktKQLQDLTEEKGTLAGEIRDMKDMLEvkerkin 550
Cdd:pfam15921 293 QANSIQSQLEIIQEQ--ARNQNSMYM----------------------RQLSDLESTVSQLRSELREAKRMYE------- 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 551 vlqKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRER---DDRERLEEIESFR 627
Cdd:pfam15921 342 ---DKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRlwdRDTGNSITIDHLR 418
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 628 KENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLfnqmynp 707
Cdd:pfam15921 419 RELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTL------- 491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 708 ahniEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRhMKDQNKKVAN 787
Cdd:pfam15921 492 ----ESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQ-MAEKDKVIEI 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 788 LKynQQLEKKknAQLLEEVRRREDSMVDNSQHLQIEelmnaLEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQ 867
Cdd:pfam15921 567 LR--QQIENM--TQLVGQHGRTAGAMQVEKAQLEKE-----INDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKL 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 868 LEEILEmKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKR-------EKDRLVHQLKQQVGRPA---RQTQNRMK 937
Cdd:pfam15921 638 VNAGSE-RLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRnfrnkseEMETTTNKLKMQLKSAQselEQTRNTLK 716
|
..
gi 568987518 938 LM 939
Cdd:pfam15921 717 SM 718
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
382-841 |
1.88e-14 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 78.14 E-value: 1.88e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 382 KALQTVIEMKDTKIASLERNIRDLEDEVQMLKANgvlnTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLAL 461
Cdd:TIGR04523 148 KKKEKELEKLNNKYNDLKKQKEELENELNLLEKE----KLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISEL 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 462 QTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKD- 540
Cdd:TIGR04523 224 KKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNq 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 541 -----MLEVKErKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRErd 615
Cdd:TIGR04523 304 keqdwNKELKS-ELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQ-- 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 616 drERLEEIESFRKENKDLKEKV-------NALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNK 688
Cdd:TIGR04523 381 --SYKQEIKNLESQINDLESKIqnqeklnQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKN 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 689 LEA---QLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDK 765
Cdd:TIGR04523 459 LDNtreSLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKES 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 766 KIAELES--------LTLRHMKDQ----NKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQhlQIEELMNALEKTR 833
Cdd:TIGR04523 539 KISDLEDelnkddfeLKKENLEKEidekNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIK--EIEEKEKKISSLE 616
|
....*...
gi 568987518 834 QELDATKA 841
Cdd:TIGR04523 617 KELEKAKK 624
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
395-945 |
1.55e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.48 E-value: 1.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 395 IASLERNIRDLEDEVQmlKANGVLNTEDREEEIkQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQnsd 474
Cdd:TIGR02168 195 LNELERQLKSLERQAE--KAERYKELKAELREL-ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEK--- 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 475 ckqhIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKER------- 547
Cdd:TIGR02168 269 ----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEelaelee 344
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 548 KINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFR 627
Cdd:TIGR02168 345 KLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 628 KENKDLKE-KVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLK--KQAEQLFNQM 704
Cdd:TIGR02168 425 ELLKKLEEaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDslERLQENLEGF 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 705 YNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAE------VDRLLEILKEVENEKNDKDKKIAELESLTLRHM 778
Cdd:TIGR02168 505 SEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGrlqavvVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGT 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 779 KDQNKKVANLKynQQLEKKKNAQLLEEVRRREDSMVDN--SQHLQIEELMNALEKTRQ----ELDATKA-RLASTQQSLA 851
Cdd:TIGR02168 585 EIQGNDREILK--NIEGFLGVAKDLVKFDPKLRKALSYllGGVLVVDDLDNALELAKKlrpgYRIVTLDgDLVRPGGVIT 662
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 852 EKEAHLANLRIERRKQLEEiLEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQVGRPARQ 931
Cdd:TIGR02168 663 GGSAKTNSSILERRREIEE-LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAE 741
|
570
....*....|....
gi 568987518 932 TQNRMKLMADNYDE 945
Cdd:TIGR02168 742 VEQLEERIAQLSKE 755
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
146-928 |
2.13e-13 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 74.77 E-value: 2.13e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 146 TMLDLQAQLKELQRENDLL----RKELDIKDSKLGSSMNSIKtfwspELKKERVLRKEEAARMSVLKEQMRvsheenqll 221
Cdd:pfam15921 111 SVIDLQTKLQEMQMERDAMadirRRESQSQEDLRNQLQNTVH-----ELEAAKCLKEDMLEDSNTQIEQLR--------- 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 222 darrtkHLQLTIQALQDELRTqrdLNHLLQQESGNRGAEHFTieLTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIET 301
Cdd:pfam15921 177 ------KMMLSHEGVLQEIRS---ILVDFEEASGKKIYEHDS--MSTMHFRSLGSAISKILRELDTEISYLKGRIFPVED 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 302 QKQTLNArdESIKKLLEMLQSKGLPSKSLEDDNE-----RTRRMAEAESQV----SHLEVILDQKEKENI----HLREEL 368
Cdd:pfam15921 246 QLEALKS--ESQNKIELLLQQHQDRIEQLISEHEveitgLTEKASSARSQAnsiqSQLEIIQEQARNQNSmymrQLSDLE 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 369 HRRSQLQPEPAKTKAL----------QTVIEMKDTKIASLERN-----IRDLEDEVQMLKANGVLNTEDREEEIKQIEVY 433
Cdd:pfam15921 324 STVSQLRSELREAKRMyedkieelekQLVLANSELTEARTERDqfsqeSGNLDDQLQKLLADLHKREKELSLEKEQNKRL 403
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 434 KSHSKFMKTKIDQLKQELSKKESELLALQTKLETLsnqNSDCKQHIEVLKESLTAKEQRAailqTEVDALRLRLEEKESF 513
Cdd:pfam15921 404 WDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAM---KSECQGQMERQMAAIQGKNESL----EKVSSLTAQLESTKEM 476
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 514 LNkktKQLQDLTEEKGTLAGEIRDMKDM---LEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtdssNTDTA 590
Cdd:pfam15921 477 LR---KVVEELTAKKMTLESSERTVSDLtasLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLR----NVQTE 549
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 591 LATLEEALSEKERIIERLKEQrerddrerleeIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDS 670
Cdd:pfam15921 550 CEALKLQMAEKDKVIEILRQQ-----------IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDA 618
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 671 KLKSLEIAIEQKKEECNKL----------EAQLKKQAEQLFNQMYNPAHNI----EDDSRMNPEFADRLKQLDKEASYYR 736
Cdd:pfam15921 619 KIRELEARVSDLELEKVKLvnagserlraVKDIKQERDQLLNEVKTSRNELnslsEDYEVLKRNFRNKSEEMETTTNKLK 698
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 737 DECGKAQAEVDRLLEILKEVE--------------NEKNDKDKKIAELESlTLRHMKDQNKKVANLKYNQQLEKKKNAQL 802
Cdd:pfam15921 699 MQLKSAQSELEQTRNTLKSMEgsdghamkvamgmqKQITAKRGQIDALQS-KIQFLEEAMTNANKEKHFLKEEKNKLSQE 777
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 803 LEEVRRREDSMVDNSQHLQIEE--LMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEIL-------- 872
Cdd:pfam15921 778 LSTVATEKNKMAGELEVLRSQErrLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQgpgytsns 857
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*..
gi 568987518 873 EMKQEALL-AAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQVGRP 928
Cdd:pfam15921 858 SMKPRLLQpASFTRTHSNVPSSQSTASFLSHHSRKTNALKEDPTRDLKQLLQELRSV 914
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
394-873 |
2.19e-13 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 74.69 E-value: 2.19e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 394 KIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHskfmKTKIDQLKQELSKKESELLALQTKLETLSNQNS 473
Cdd:PRK02224 207 RLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVR 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 474 DCKQHIEVLKESLT--------------AKEQRAAILQTEVDALRLRLEEKESFLNKKTKQL--------------QDLT 525
Cdd:PRK02224 283 DLRERLEELEEERDdllaeaglddadaeAVEARREELEDRDEELRDRLEECRVAAQAHNEEAeslredaddleeraEELR 362
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 526 EEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERII 605
Cdd:PRK02224 363 EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERV 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 606 ERLKEQRE--------------------RDDRERLEEIES----FRKENKDLKEKVNALQaELTEKESSLIDLKEHASSL 661
Cdd:PRK02224 443 EEAEALLEagkcpecgqpvegsphvetiEEDRERVEELEAeledLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDL 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 662 ASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQlfnqmynpAHNIEDDSRmnpEFADRLKQLDKEasyyRDECGK 741
Cdd:PRK02224 522 EELIAERRETIEEKRERAEELRERAAELEAEAEEKREA--------AAEAEEEAE---EAREEVAELNSK----LAELKE 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 742 AQAEVDRLLEILKEVEN------EKNDKDKKIAELESLTLRHMKDQNKKVAnlkynqQLEKKKNAQLLEEVRRREDSMVD 815
Cdd:PRK02224 587 RIESLERIRTLLAAIADaedeieRLREKREALAELNDERRERLAEKRERKR------ELEAEFDEARIEEAREDKERAEE 660
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 568987518 816 nsqhlQIEELMNALEKTRQELDATKARLASTQQSLAEkeahLANLRiERRKQLEEILE 873
Cdd:PRK02224 661 -----YLEQVEEKLDELREERDDLQAEIGAVENELEE----LEELR-ERREALENRVE 708
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
268-946 |
2.87e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 74.79 E-value: 2.87e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 268 EENFRRLQAEHDRQAKELFLLRKTleEMELRIETQKQTLNARD-ESIKKLLEMLQSKGLpSKSLEDDNERTRRMAEAESQ 346
Cdd:PTZ00121 1137 EDARKAEEARKAEDAKRVEIARKA--EDARKAEEARKAEDAKKaEAARKAEEVRKAEEL-RKAEDARKAEAARKAEEERK 1213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 347 VSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEvQMLKANGVLNTED--RE 424
Cdd:PTZ00121 1214 AEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAE-EARKADELKKAEEkkKA 1292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 425 EEIKQIEVYKSHSKFMKTKIDQLKQELSKKESEllALQTKLETLSNQNSDCKQHIEVLK--ESLTAKEQRAAILQTEVDA 502
Cdd:PTZ00121 1293 DEAKKAEEKKKADEAKKKAEEAKKADEAKKKAE--EAKKKADAAKKKAEEAKKAAEAAKaeAEAAADEAEAAEEKAEAAE 1370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 503 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKinvlQKKIENLQEQLRDKDKqltnlKDRVKSLQT 582
Cdd:PTZ00121 1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA----KKKADEAKKKAEEKKK-----ADEAKKKAE 1441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 583 DSSNTDTALATLEEAlSEKERIIERLKEQRERDDRERLEE----IESFRKENKDLKEKVNALQAELTEKESSLIDLKEHA 658
Cdd:PTZ00121 1442 EAKKADEAKKKAEEA-KKAEEAKKKAEEAKKADEAKKKAEeakkADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE 1520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 659 SSLASAGLKRDSKLKSLEI--AIEQKKEECNKLEAQLKKQAEQlfnQMYNPAHNIEDDSRMNPEFADRLKQLDKeasyyr 736
Cdd:PTZ00121 1521 AKKADEAKKAEEAKKADEAkkAEEKKKADELKKAEELKKAEEK---KKAEEAKKAEEDKNMALRKAEEAKKAEE------ 1591
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 737 decgKAQAEVDRLLEILKEVENEKNDKDKKiAELESLTLRHMKDQNKKVANLKYNQQLEKKKnaqlLEEVRRREDSmvdn 816
Cdd:PTZ00121 1592 ----ARIEEVMKLYEEEKKMKAEEAKKAEE-AKIKAEELKKAEEEKKKVEQLKKKEAEEKKK----AEELKKAEEE---- 1658
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 817 sqhlqiEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEM------KQEALLAAISEKDANI 890
Cdd:PTZ00121 1659 ------NKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKeaeekkKAEELKKAEEENKIKA 1732
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*.
gi 568987518 891 ALLELSASKKKKTQEEVMALKREKDRLVHQLKQQVGRPARQTQNRMKLMADNYDED 946
Cdd:PTZ00121 1733 EEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEE 1788
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
339-873 |
3.78e-13 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 73.92 E-value: 3.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 339 RMAEAESQVSHLEVILDQKEKENIHLREELhrrsqlqpepaktKALQTVI---EMKDTKIASLERNIRDLEDEVQmlkan 415
Cdd:PRK02224 207 RLNGLESELAELDEEIERYEEQREQARETR-------------DEADEVLeehEERREELETLEAEIEDLRETIA----- 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 416 gvlNTEDREEEIK-QIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAA 494
Cdd:PRK02224 269 ---ETEREREELAeEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAE 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 495 ILQTEVDALRLRLEEKEsflnkktkqlqdltEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLK 574
Cdd:PRK02224 346 SLREDADDLEERAEELR--------------EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 575 DRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRE--------------------RDDRERLEEIES----FRKEN 630
Cdd:PRK02224 412 DFLEELREERDELREREAELEATLRTARERVEEAEALLEagkcpecgqpvegsphvetiEEDRERVEELEAeledLEEEV 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 631 KDLKEKVNALQaELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQlfnqmynpAHN 710
Cdd:PRK02224 492 EEVEERLERAE-DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREA--------AAE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 711 IEDDSRmnpEFADRLKQLDKEasyyRDECGKAQAEVDRLLEILKEVEN------EKNDKDKKIAELESLTLRHMKDQNKK 784
Cdd:PRK02224 563 AEEEAE---EAREEVAELNSK----LAELKERIESLERIRTLLAAIADaedeieRLREKREALAELNDERRERLAEKRER 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 785 VANL-------KYNQQLEKKKNAQL--------LEEVRRREDS------MVDNSqhlqIEELmNALEKTRQELDATKARL 843
Cdd:PRK02224 636 KRELeaefdeaRIEEAREDKERAEEyleqveekLDELREERDDlqaeigAVENE----LEEL-EELRERREALENRVEAL 710
|
570 580 590
....*....|....*....|....*....|
gi 568987518 844 ASTQQSLAEKEAHLANLRIERRKQLEEILE 873
Cdd:PRK02224 711 EALYDEAEELESMYGDLRAELRQRNVETLE 740
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
443-794 |
2.17e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 71.63 E-value: 2.17e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 443 KIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEvLKESLTAKEqrAAILQTEVDALRLRLEEKESFLNKKTKQLQ 522
Cdd:TIGR02168 180 KLERTRENLDRLEDILNELERQLKSLERQAEKAERYKE-LKAELRELE--LALLVLRLEELREELEELQEELKEAEEELE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 523 DLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKE 602
Cdd:TIGR02168 257 ELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 603 RIIERLKEQRErddrerleeiesfrkenkDLKEKVNALQAELTEK-------ESSLIDLKEHASSLASAGLKRDSKLKSL 675
Cdd:TIGR02168 337 EELAELEEKLE------------------ELKEELESLEAELEELeaeleelESRLEELEEQLETLRSKVAQLELQIASL 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 676 EIAIEQKKEECNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADR-LKQLDKEASYYRDECGKAQAEVDRLLEILK 754
Cdd:TIGR02168 399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEeLEELQEELERLEEALEELREELEEAEQALD 478
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 568987518 755 EVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKYNQQL 794
Cdd:TIGR02168 479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGL 518
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
484-700 |
7.97e-12 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 68.25 E-value: 7.97e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 484 ESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQL 563
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 564 rdkDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRerddRERLEEIESFRKENKDLKEKVNALQAE 643
Cdd:COG4942 100 ---EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLA----PARREQAEELRADLAELAALRAELEAE 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 568987518 644 LTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEEcnklEAQLKKQAEQL 700
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAE----LAELQQEAEEL 225
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
496-882 |
8.84e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 69.71 E-value: 8.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 496 LQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIrdmkdmlEVKERKINVLQKKIENLQEQLRDKDKQLTNLKD 575
Cdd:TIGR02169 686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI-------EQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 576 RvkslqtdssntdtaLATLEEALSEKERIIERLKEQRER-DDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLidl 654
Cdd:TIGR02169 759 E--------------LKELEARIEELEEDLHKLEEALNDlEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKL--- 821
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 655 kehasslasagLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQlfnqmynpahnIEDDSRMNPEFADRLKQLDKEASY 734
Cdd:TIGR02169 822 -----------NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE-----------IENLNGKKEELEEELEELEAALRD 879
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 735 YRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESltlrHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMV 814
Cdd:TIGR02169 880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRK----RLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLED 955
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568987518 815 DNSQHLQIEELMNALE----KTRQELDATKARLastqQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAA 882
Cdd:TIGR02169 956 VQAELQRVEEEIRALEpvnmLAIQEYEEVLKRL----DELKEKRAKLEEERKAILERIEEYEKKKREVFMEA 1023
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
232-655 |
1.66e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 68.53 E-value: 1.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 232 TIQALQDELRTQRD-LNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARD 310
Cdd:PRK02224 311 AVEARREELEDRDEeLRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELE 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 311 ESIKKLLEMLQSKGLPSKSLEDDNERTR-RMAEAESQVSHLEVILdQKEKENIHLREELHRRSQLqPE---PAKTKALQT 386
Cdd:PRK02224 391 EEIEELRERFGDAPVDLGNAEDFLEELReERDELREREAELEATL-RTARERVEEAEALLEAGKC-PEcgqPVEGSPHVE 468
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 387 VIEMKDTKIASLERNIRDLEDEVqmlkangvlntEDREEEIKQIEvykshskfmktkidqlkqELSKKESELLALQTKLE 466
Cdd:PRK02224 469 TIEEDRERVEELEAELEDLEEEV-----------EEVEERLERAE------------------DLVEAEDRIERLEERRE 519
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 467 TLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE------IRDMKD 540
Cdd:PRK02224 520 DLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERieslerIRTLLA 599
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 541 MLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQT--DSSNTDTALATLEEALSEKERIIERLKEQRERDD-- 616
Cdd:PRK02224 600 AIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAefDEARIEEAREDKERAEEYLEQVEEKLDELREERDdl 679
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 568987518 617 -------RERLEEIESFRKENKDLKEKVNALQA---ELTEKESSLIDLK 655
Cdd:PRK02224 680 qaeigavENELEELEELRERREALENRVEALEAlydEAEELESMYGDLR 728
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
338-925 |
8.60e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 66.24 E-value: 8.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 338 RRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAK---------TKALQTVIEMKDTKIASLERNIRDLEDE 408
Cdd:TIGR02169 237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdlgeeeQLRVKEKIGELEAEIASLERSIAEKERE 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 409 VqmlkangvlntEDREEEIKQIEVykshskfmktKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTA 488
Cdd:TIGR02169 317 L-----------EDAEERLAKLEA----------EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 489 KEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDK 568
Cdd:TIGR02169 376 VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 569 QLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQReRDDRERLEEIESFRKENKDLKEKVNALQAELTEKE 648
Cdd:TIGR02169 456 KLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA-RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVG 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 649 sslidlKEHASSLASAGLKRdskLKSLEIAIEQKKEECNKLEAQLK------------KQAEQL---------------- 700
Cdd:TIGR02169 535 ------ERYATAIEVAAGNR---LNNVVVEDDAVAKEAIELLKRRKagratflplnkmRDERRDlsilsedgvigfavdl 605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 701 --FNQMYNPA-----------HNIEDDSRMNPEFadRLKQLDKE--------ASYYRDECGKA------QAEVDRLLEIL 753
Cdd:TIGR02169 606 veFDPKYEPAfkyvfgdtlvvEDIEAARRLMGKY--RMVTLEGElfeksgamTGGSRAPRGGIlfsrsePAELQRLRERL 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 754 KEVENEKNDKDKKIAELESLT---LRHMKDQNKKVANLKYNQQL---EKKKNAQLLEEVRRR-----------EDSMVDN 816
Cdd:TIGR02169 684 EGLKRELSSLQSELRRIENRLdelSQELSDASRKIGEIEKEIEQleqEEEKLKERLEELEEDlssleqeienvKSELKEL 763
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 817 S-----QHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIA 891
Cdd:TIGR02169 764 EarieeLEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI 843
|
650 660 670
....*....|....*....|....*....|....
gi 568987518 892 LLELSASKKKKTQEEVMALKREKDRLVHQLKQQV 925
Cdd:TIGR02169 844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAAL 877
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
306-933 |
1.16e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.85 E-value: 1.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 306 LNARDESIKKLLEmlQSKGLpSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLreelhrrsQLQPEPAKtKALQ 385
Cdd:TIGR02168 150 IEAKPEERRAIFE--EAAGI-SKYKERRKETERKLERTRENLDRLEDILNELERQLKSL--------ERQAEKAE-RYKE 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 386 TVIEMKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKShskfmktKIDQLKQELSKKESELLALQTKL 465
Cdd:TIGR02168 218 LKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE-------KLEELRLEVSELEEEIEELQKEL 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 466 ETLSNQNSDCKQHIEVLKESLtakeqraAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVK 545
Cdd:TIGR02168 291 YALANEISRLEQQKQILRERL-------ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 546 ERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERL-EEIE 624
Cdd:TIGR02168 364 EAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELqAELE 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 625 SFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEiAIEQKKEECNKLEAQLKKQAEQL---- 700
Cdd:TIGR02168 444 ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE-RLQENLEGFSEGVKALLKNQSGLsgil 522
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 701 --------FNQMYNPAHNIEDDSRM------NPEFADRLKQLDKEASYYR------DECGKAQAEVDRLlEILKEVENEK 760
Cdd:TIGR02168 523 gvlselisVDEGYEAAIEAALGGRLqavvveNLNAAKKAIAFLKQNELGRvtflplDSIKGTEIQGNDR-EILKNIEGFL 601
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 761 ---NDKDKKIAELESLtLRHMKDQNKKVANLKYNQQLEKKKNAQ----------------LLEEVRRREDSMVDNSQHL- 820
Cdd:TIGR02168 602 gvaKDLVKFDPKLRKA-LSYLLGGVLVVDDLDNALELAKKLRPGyrivtldgdlvrpggvITGGSAKTNSSILERRREIe 680
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 821 ----QIEELMNALEKTRQELDATKARLASTQQ--SLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLE 894
Cdd:TIGR02168 681 eleeKIEELEEKIAELEKALAELRKELEELEEelEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760
|
650 660 670
....*....|....*....|....*....|....*....
gi 568987518 895 LSASKKKKTQEEVMALKREKDRLVHQLKQQVGRPARQTQ 933
Cdd:TIGR02168 761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK 799
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
262-695 |
1.59e-10 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 65.04 E-value: 1.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 262 FTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQS--KGLPSKSLEDDNERTRr 339
Cdd:TIGR04523 204 SNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKikKQLSEKQKELEQNNKK- 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 340 MAEAESQVSHLEV-ILDQKEKENIHLREELHrrSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKANGVL 418
Cdd:TIGR04523 283 IKELEKQLNQLKSeISDLNNQKEQDWNKELK--SELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSE 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 419 NTEDREEEIKQIEV-------YKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQ 491
Cdd:TIGR04523 361 KQRELEEKQNEIEKlkkenqsYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNS 440
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 492 RAAILQTEVDALRLRLEEkesfLNKKTKQLQDLTEekgTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLT 571
Cdd:TIGR04523 441 EIKDLTNQDSVKELIIKN----LDNTRESLETQLK---VLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVK 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 572 NLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRErlEEIESFRKENKDLKEKVNALQAELTEKESSL 651
Cdd:TIGR04523 514 DLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLE--KEIDEKNKEIEELKQTQKSLKKKQEEKQELI 591
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 568987518 652 IDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKK 695
Cdd:TIGR04523 592 DQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
264-623 |
2.51e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.69 E-value: 2.51e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 264 IELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRmaEA 343
Cdd:TIGR02168 679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK--EL 756
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 344 ESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALqtviemkdtkIASLERNIRDLEDEVQMLKANGVLNTEDR 423
Cdd:TIGR02168 757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE----------LKALREALDELRAELTLLNEEAANLRERL 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 424 EEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQnsdckqhIEVLKESLTAKEQRAAILQTEVDAL 503
Cdd:TIGR02168 827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE-------LEALLNERASLEEALALLRSELEEL 899
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 504 RLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDML-EVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQT 582
Cdd:TIGR02168 900 SEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIdNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLEN 979
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 568987518 583 DSSNT-DTALATLEEALSEKERIIErLKEQRE--RDDRERLEEI 623
Cdd:TIGR02168 980 KIKELgPVNLAAIEEYEELKERYDF-LTAQKEdlTEAKETLEEA 1022
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
148-772 |
2.80e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.57 E-value: 2.80e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 148 LDLQAQLKELQREndLLRKELDIKDSKLGSSMNSIKtfwspELKKERVLRKEEAARMSVLKEQMRVSHEENQLLDARRTK 227
Cdd:COG1196 216 RELKEELKELEAE--LLLLKLRELEAELEELEAELE-----ELEAELEELEAELAELEAELEELRLELEELELELEEAQA 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 228 HLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLN 307
Cdd:COG1196 289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 308 ARDESIKKLLEMLQSKglpsksLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQlqpepAKTKALQTV 387
Cdd:COG1196 369 EAEAELAEAEEELEEL------AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEE-----ALAELEEEE 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 388 IEMKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKfmKTKIDQLKQELSKKESELLALQTKLET 467
Cdd:COG1196 438 EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE--AAARLLLLLEAEADYEGFLEGVKAALL 515
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 468 LSNQnsdCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKER 547
Cdd:COG1196 516 LAGL---RGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAL 592
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 548 KINVLQKKIENLQEQLRDKDKQLTNLKDrvkSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERddRERLEEIESFR 627
Cdd:COG1196 593 ARGAIGAAVDLVASDLREADARYYVLGD---TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGG--SAGGSLTGGSR 667
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 628 KENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEEcnkLEAQLKKQAEQLFNQMYNP 707
Cdd:COG1196 668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEA---LEEQLEAEREELLEELLEE 744
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568987518 708 AHNIEDDSRMNPEFADRLKQLDKEASyyrdecgKAQAEVDRL-------LEILKEVENEKNDKDKKIAELES 772
Cdd:COG1196 745 EELLEEEALEELPEPPDLEELERELE-------RLEREIEALgpvnllaIEEYEELEERYDFLSEQREDLEE 809
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
227-789 |
4.93e-10 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 63.93 E-value: 4.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 227 KHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHD---RQAKELFLLRKTLEEMELRIETQK 303
Cdd:PRK03918 172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEELEKELESLE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 304 QTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQlqpEPAKTKA 383
Cdd:PRK03918 252 GSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEE---EINGIEE 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 384 LQTVIEMKDTKIASLERNIRDLEDEVQMLKA-----NGVLNTEDREEEIKQIEVYKSHSKfMKTKIDQLKQELSKKESEL 458
Cdd:PRK03918 329 RIKELEEKEERLEELKKKLKELEKRLEELEErhelyEEAKAKKEELERLKKRLTGLTPEK-LEKELEELEKAKEEIEEEI 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 459 LALQTKLETLSNQNSDCKQHIEVLKES---------LTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKG 529
Cdd:PRK03918 408 SKITARIGELKKEIKELKKAIEELKKAkgkcpvcgrELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEK 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 530 TLAGE-----IRDMKDMLEVKERKINVLQ--------KKIENLQEQLRDKDKQLTNLKDRVKSLQ---TDSSNTDTALAT 593
Cdd:PRK03918 488 VLKKEselikLKELAEQLKELEEKLKKYNleelekkaEEYEKLKEKLIKLKGEIKSLKKELEKLEelkKKLAELEKKLDE 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 594 LEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEkesslidlkehasslasaglkrdskLK 673
Cdd:PRK03918 568 LEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKE-------------------------LK 622
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 674 SLEIAIEQKKEECNKLEAQLKKQAEQL--FNQMYNpahniEDDSRmnpEFADRLKQLDKEASYYRDECGKAQAEVDRLLE 751
Cdd:PRK03918 623 KLEEELDKAFEELAETEKRLEELRKELeeLEKKYS-----EEEYE---ELREEYLELSRELAGLRAELEELEKRREEIKK 694
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 568987518 752 ILKEVENEKNDKDKKIAELESL--TLRHMKDQNKKVANLK 789
Cdd:PRK03918 695 TLEKLKEELEEREKAKKELEKLekALERVEELREKVKKYK 734
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
156-841 |
5.93e-10 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 63.62 E-value: 5.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 156 ELQRENDLLRKELDIKdsKLGSSMNSIKTFWSPELKKERVLRKEEAARMSvlkEQMRVSHEENQLLDARRTKHLQLTIQA 235
Cdd:PTZ00121 1161 EDARKAEEARKAEDAK--KAEAARKAEEVRKAEELRKAEDARKAEAARKA---EEERKAEEARKAEDAKKAEAVKKAEEA 1235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 236 LQDELRTQRdlnhlLQQESGNRGAEHFTIELTEENFRR---LQAEHDRQAKELFLLRKTLEEMELRIETQKQTLnarDES 312
Cdd:PTZ00121 1236 KKDAEEAKK-----AEEERNNEEIRKFEEARMAHFARRqaaIKAEEARKADELKKAEEKKKADEAKKAEEKKKA---DEA 1307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 313 IKKLLEMLQSKGLPSKSLEDDN--ERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEM 390
Cdd:PTZ00121 1308 KKKAEEAKKADEAKKKAEEAKKkaDAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA 1387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 391 KDTKIA-SLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESEllalQTKLETLS 469
Cdd:PTZ00121 1388 EEKKKAdEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEE----AKKAEEAK 1463
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 470 NQNSDCKQHIEVLKESLTAKE-----QRAAILQTEVDALRLRLEEKE-------SFLNKKTKQLQDLTE----EKGTLAG 533
Cdd:PTZ00121 1464 KKAEEAKKADEAKKKAEEAKKadeakKKAEEAKKKADEAKKAAEAKKkadeakkAEEAKKADEAKKAEEakkaDEAKKAE 1543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 534 EIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLK-----DRVKSLQTDSSNTDTALATLEEALSEKERIIERL 608
Cdd:PTZ00121 1544 EKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEeakkaEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 609 KEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNK 688
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK 1703
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 689 LEAQLKKQAEQLfnqmyNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKkia 768
Cdd:PTZ00121 1704 AEELKKKEAEEK-----KKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRK--- 1775
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568987518 769 ELESLTLRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKA 841
Cdd:PTZ00121 1776 EKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADA 1848
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
441-649 |
1.37e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 61.32 E-value: 1.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 441 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 520
Cdd:COG4942 26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 521 LQDL------TEEKGTL-----AGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT 589
Cdd:COG4942 106 LAELlralyrLGRQPPLalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 590 ALATLEEALSEKERIIERLKEQRERDDrerlEEIESFRKENKDLKEKVNALQAELTEKES 649
Cdd:COG4942 186 ERAALEALKAERQKLLARLEKELAELA----AELAELQQEAEELEALIARLEAEAAAAAE 241
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
511-703 |
1.71e-09 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 61.00 E-value: 1.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 511 ESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLT-----------NLKDRVKS 579
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAeaeaeieerreELGERARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 580 LQTDSSNTDTALATLE----EALSEKERIIERLKEQrerdDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLK 655
Cdd:COG3883 95 LYRSGGSVSYLDVLLGsesfSDFLDRLSALSKIADA----DADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 568987518 656 EhasSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLFNQ 703
Cdd:COG3883 171 A---ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
440-642 |
1.13e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 59.54 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 440 MKTKIDQLK---QELSKKESELLALQTKLETLSNQNSDCKQHIEvLKESLTAKEQRAAIL-----QTEVDALRLRLEEKE 511
Cdd:COG4913 223 TFEAADALVehfDDLERAHEALEDAREQIELLEPIRELAERYAA-ARERLAELEYLRAALrlwfaQRRLELLEAELEELR 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 512 SFLNKKTKQLQDLTEEKGTLAGEIRDMK-DMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTA 590
Cdd:COG4913 302 AELARLEAELERLEARLDALREELDELEaQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEE 381
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 568987518 591 LATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQA 642
Cdd:COG4913 382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLER 433
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
139-611 |
1.23e-08 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 59.36 E-value: 1.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 139 LRQVRD--STMLDLQAQLKELQR----ENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEeAARMSVLKEQMR 212
Cdd:pfam15921 316 MRQLSDleSTVSQLRSELREAKRmyedKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKL-LADLHKREKELS 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 213 VSHEENQLLDARRTKHlQLTIQALQDEL--------RTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKE 284
Cdd:pfam15921 395 LEKEQNKRLWDRDTGN-SITIDHLRRELddrnmevqRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLEST 473
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 285 LFLLRKTLEEMElrieTQKQTLNARDESIKKLLEMLQskglpsksleddnERTRRMAEAESQVSHLEVILDQKEKENIHL 364
Cdd:pfam15921 474 KEMLRKVVEELT----AKKMTLESSERTVSDLTASLQ-------------EKERAIEATNAEITKLRSRVDLKLQELQHL 536
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 365 REElhrRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEV-QMLKANGVLNTEDR--EEEIKQIEVYKSHSKFMK 441
Cdd:pfam15921 537 KNE---GDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVgQHGRTAGAMQVEKAqlEKEINDRRLELQEFKILK 613
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 442 TKIDQLKQELSKKESELLALQTKL------------------ETLSNQNSDCKQHI-------EVLKESLTAKEQRaaiL 496
Cdd:pfam15921 614 DKKDAKIRELEARVSDLELEKVKLvnagserlravkdikqerDQLLNEVKTSRNELnslsedyEVLKRNFRNKSEE---M 690
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 497 QTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDR 576
Cdd:pfam15921 691 ETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEE 770
|
490 500 510
....*....|....*....|....*....|....*...
gi 568987518 577 VKSLQTDSSNTDT---ALATLEEALSEKERiieRLKEQ 611
Cdd:pfam15921 771 KNKLSQELSTVATeknKMAGELEVLRSQER---RLKEK 805
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
209-799 |
1.63e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 58.58 E-value: 1.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 209 EQMRVSHEENQLLDARRTKHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLL 288
Cdd:pfam05483 222 EKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDI 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 289 RKTLEEMELRIETQKQTLNARDESIKKLLEmlqskglpsksleddnERTRRMAEAESQVSHLEVILDQKEKENIHLrEEL 368
Cdd:pfam05483 302 KMSLQRSMSTQKALEEDLQIATKTICQLTE----------------EKEAQMEELNKAKAAHSFVVTEFEATTCSL-EEL 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 369 HRRSQLQPEPAKTKALQTVIEmkdtkiasLERNIRDLEDEVQMLKangvlNTEDREEEIKQIEVYKSHSKFMKTKIDQLK 448
Cdd:pfam05483 365 LRTEQQRLEKNEDQLKIITME--------LQKKSSELEEMTKFKN-----NKEVELEELKKILAEDEKLLDEKKQFEKIA 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 449 QELSKKESELLALqtkLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEK 528
Cdd:pfam05483 432 EELKGKEQELIFL---LQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEA 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 529 GTLAGEIRDMKDMLEVKERKINVLQKKIENLQEqlrdkdkQLTNLKDRVKSLQtdssntdtalatlEEALSEKERIIERL 608
Cdd:pfam05483 509 SDMTLELKKHQEDIINCKKQEERMLKQIENLEE-------KEMNLRDELESVR-------------EEFIQKGDEVKCKL 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 609 kEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIeqkkeecNK 688
Cdd:pfam05483 569 -DKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKV-------NK 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 689 LEAQLkKQAEQLFNQMYNPAHNIEDDSRMNPEfadRLKQLDKEASYYRDECGKAQAEVD-----RLLEILKEVENEKNDK 763
Cdd:pfam05483 641 LELEL-ASAKQKFEEIIDNYQKEIEDKKISEE---KLLEEVEKAKAIADEAVKLQKEIDkrcqhKIAEMVALMEKHKHQY 716
|
570 580 590
....*....|....*....|....*....|....*..
gi 568987518 764 DKKIAELES-LTLRHMKDQNKKVANLKYNQQLEKKKN 799
Cdd:pfam05483 717 DKIIEERDSeLGLYKNKEQEQSSAKAALEIELSNIKA 753
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
514-923 |
1.73e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.54 E-value: 1.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 514 LNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQL---RDKDKQLTNLKDRVKSLQTDSSNTDTA 590
Cdd:PRK03918 174 IKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELeklEKEVKELEELKEEIEELEKELESLEGS 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 591 LATLEEALSEKERIIERLKEQRE--RDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKR 668
Cdd:PRK03918 254 KRKLEEKIRELEERIEELKKEIEelEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 669 DSKLKSLEiAIEQKKEECNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDEcgkAQAEVDR 748
Cdd:PRK03918 334 EEKEERLE-ELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEE---IEEEISK 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 749 LLEILKEVENEKNDKDKKIAELES------LTLRHMKDQNKKVANLKYNQQLEK--KKNAQLLEEVRRREDSMVDNSQHL 820
Cdd:PRK03918 410 ITARIGELKKEIKELKKAIEELKKakgkcpVCGRELTEEHRKELLEEYTAELKRieKELKEIEEKERKLRKELRELEKVL 489
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 821 QIEELMNALEKTRQELDATKARLASTQQSLAEKEAHlanlriERRKQLEEILEMKQEallaaISEKDANIALLELSASKK 900
Cdd:PRK03918 490 KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAE------EYEKLKEKLIKLKGE-----IKSLKKELEKLEELKKKL 558
|
410 420
....*....|....*....|...
gi 568987518 901 KKTQEEVMALKREKDRLVHQLKQ 923
Cdd:PRK03918 559 AELEKKLDELEEELAELLKELEE 581
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
591-917 |
2.62e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.16 E-value: 2.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 591 LATLEEALSEKERIIERLKEQRERDDR------ERLEEIESFRKEnKDLKEKVNALQAELTEKESSLidlkehassLASA 664
Cdd:TIGR02169 162 IAGVAEFDRKKEKALEELEEVEENIERldliidEKRQQLERLRRE-REKAERYQALLKEKREYEGYE---------LLKE 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 665 GLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLfnqmynpaHNIEDDSRmnpEFADRLKQL-DKEASYYRDECGKAQ 743
Cdd:TIGR02169 232 KEALERQKEAIERQLASLEEELEKLTEEISELEKRL--------EEIEQLLE---ELNKKIKDLgEEEQLRVKEKIGELE 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 744 AEVDRLLEILKEVENEKNDKDKKIAELESLTLRhmkdQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQhlQIE 823
Cdd:TIGR02169 301 AEIASLERSIAEKERELEDAEERLAKLEAEIDK----LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA--ELE 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 824 ELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQE------ALLAAISEKDANIALLELSA 897
Cdd:TIGR02169 375 EVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAiagieaKINELEEEKEDKALEIKKQE 454
|
330 340
....*....|....*....|
gi 568987518 898 SKKKKTQEEVMALKREKDRL 917
Cdd:TIGR02169 455 WKLEQLAADLSKYEQELYDL 474
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
292-887 |
2.73e-08 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 57.99 E-value: 2.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 292 LEEMELRIETQKQTLNARDESIKKLLEMLQSKGLP----SKSLEDDNERTRRMaeaESQVSHLEVILDQKEKENIHLREE 367
Cdd:PRK01156 164 LERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLEleniKKQIADDEKSHSIT---LKEIERLSIEYNNAMDDYNNLKSA 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 368 LHRRSQLQPEPAKtkalqtviemkdtkiasLERNIRDLEDEVQM--LKANGVLNTEDREEEIKQIEVYKSHSKF-----M 440
Cdd:PRK01156 241 LNELSSLEDMKNR-----------------YESEIKTAESDLSMelEKNNYYKELEERHMKIINDPVYKNRNYIndyfkY 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 441 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKEsltakeqraailQTEVDALRLRLEEKESFLNKKTKQ 520
Cdd:PRK01156 304 KNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSR------------YDDLNNQILELEGYEMDYNSYLKS 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 521 LQDLTEEKGTLAGEIRDMKD----MLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEe 596
Cdd:PRK01156 372 IESLKKKIEEYSKNIERMSAfiseILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLN- 450
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 597 ALSEKERIIERLKEQRERDDRERLEEiesfrkENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKR----DSKL 672
Cdd:PRK01156 451 GQSVCPVCGTTLGEEKSNHIINHYNE------KKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKsineYNKI 524
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 673 KSLEIAIEQKKEECNKLEAQLKKqAEQLFNQmYNPAHnIEDDSRMNPEFADRLKQ---LDKEASYYRDECGKAQAE--VD 747
Cdd:PRK01156 525 ESARADLEDIKIKINELKDKHDK-YEEIKNR-YKSLK-LEDLDSKRTSWLNALAVislIDIETNRSRSNEIKKQLNdlES 601
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 748 RLLEILKEVENEKNDKDKKIAELESlTLRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRR---REDSMVD-NSQHLQIE 823
Cdd:PRK01156 602 RLQEIEIGFPDDKSYIDKSIREIEN-EANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEidsIIPDLKEiTSRINDIE 680
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568987518 824 ELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEeilemKQEALLAAISEKD 887
Cdd:PRK01156 681 DNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLE-----SMKKIKKAIGDLK 739
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
446-908 |
3.00e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.86 E-value: 3.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 446 QLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQtevdaLRLRLEEKESFLNKKTKQLQDLT 525
Cdd:COG4717 78 EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP-----LYQELEALEAELAELPERLEELE 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 526 EEkgtlAGEIRDMKDMLEVKERKINVLQKKIENLQEQLR-DKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERI 604
Cdd:COG4717 153 ER----LEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEE 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 605 IERLKEQRER-DDRERLEEIESFRKenkdLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK 683
Cdd:COG4717 229 LEQLENELEAaALEERLKEARLLLL----IAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 684 EECNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDEcgKAQAEVDRLLEILKEVENEKNDK 763
Cdd:COG4717 305 EELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL--EEELQLEELEQEIAALLAEAGVE 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 764 DkkiaeLESLTLRHMKDQnkkvanlKYNQQLEKKKNAQllEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARL 843
Cdd:COG4717 383 D-----EEELRAALEQAE-------EYQELKEELEELE--EQLEELLGELEELLEALDEEELEEELEELEEELEELEEEL 448
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568987518 844 ASTQQSLAEKEAHLANLriERRKQLEEILEmKQEALLAAISEKDANIALLELSASKKKKTQEEVM 908
Cdd:COG4717 449 EELREELAELEAELEQL--EEDGELAELLQ-ELEELKAELRELAEEWAALKLALELLEEAREEYR 510
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
441-667 |
3.71e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 56.70 E-value: 3.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 441 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 520
Cdd:COG4942 33 QQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 521 LQDL-TEEKGTLAGEIRDMKDMLevkeRKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSsntdTALATLEEALS 599
Cdd:COG4942 113 LYRLgRQPPLALLLSPEDFLDAV----RRLQYLKYLAPARREQAEELRADLAELAALRAELEAER----AELEALLAELE 184
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568987518 600 EKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLK 667
Cdd:COG4942 185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALK 252
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
338-921 |
7.27e-08 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.85 E-value: 7.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 338 RRMAEAESQVSHLEVILDQKEKenihLREELHRRSQLQPEPAKTKALQtviemKDTKIASLERNIRDLEDEVQMLKAngv 417
Cdd:COG4913 242 EALEDAREQIELLEPIRELAER----YAAARERLAELEYLRAALRLWF-----AQRRLELLEAELEELRAELARLEA--- 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 418 lntedreeeikqievykshskfmktKIDQLKQELSKKESELLALQTKLETLSNQN-SDCKQHIEVLKESLTAKEQRAAIL 496
Cdd:COG4913 310 -------------------------ELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLERELEERERRRARL 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 497 QTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKinvlqkkienLQEQLRDKDKQLTNLKDR 576
Cdd:COG4913 365 EALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRD----------LRRELRELEAEIASLERR 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 577 VKSLqtdSSNTDTALATLEEALSEKE---RIIERLKEQRERDDR-----ERL------------EEIESFRK--ENKDLK 634
Cdd:COG4913 435 KSNI---PARLLALRDALAEALGLDEaelPFVGELIEVRPEEERwrgaiERVlggfaltllvppEHYAAALRwvNRLHLR 511
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 635 EKVNALQAELTEKESSLIDLkeHASSLASaglkrdsKLKSLEIAIEqkkeecNKLEAQLKKQ--------AEQLFN---- 702
Cdd:COG4913 512 GRLVYERVRTGLPDPERPRL--DPDSLAG-------KLDFKPHPFR------AWLEAELGRRfdyvcvdsPEELRRhpra 576
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 703 -----QMYNP----AHNIEDDSRMNPEF----ADRLKQLDKEAsyyrdecGKAQAEVDRLLEILKEVENEKNDKDKKIAE 769
Cdd:COG4913 577 itragQVKGNgtrhEKDDRRRIRSRYVLgfdnRAKLAALEAEL-------AELEEELAEAEERLEALEAELDALQERREA 649
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 770 LESLTLRHMKDQNKKVANLKYNQqlekkknaqlLEEVRRREDSmvDNSQHLQIEELMNALEKTRQELDATKARLASTQQS 849
Cdd:COG4913 650 LQRLAEYSWDEIDVASAEREIAE----------LEAELERLDA--SSDDLAALEEQLEELEAELEELEEELDELKGEIGR 717
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568987518 850 LAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQL 921
Cdd:COG4913 718 LEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
518-924 |
9.72e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 56.18 E-value: 9.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 518 TKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEA 597
Cdd:TIGR04523 39 EKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQ 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 598 LSEKERIIERLKEQRERDDRER---LEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKL-- 672
Cdd:TIGR04523 119 KNKLEVELNKLEKQKKENKKNIdkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLlk 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 673 -----------------------------KSLEIAIEQKKEECNKLEAQLKKQAEQLF----------NQMYNPAHNIED 713
Cdd:TIGR04523 199 lelllsnlkkkiqknkslesqiselkkqnNQLKDNIEKKQQEINEKTTEISNTQTQLNqlkdeqnkikKQLSEKQKELEQ 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 714 DSRMNPEFADRLKQLDKEASYYRDEcgKAQAEVDRLLEILKEVENEKNDKDKKIAELESlTLRHMKDQ---------NKK 784
Cdd:TIGR04523 279 NNKKIKELEKQLNQLKSEISDLNNQ--KEQDWNKELKSELKNQEKKLEEIQNQISQNNK-IISQLNEQisqlkkeltNSE 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 785 VANLKYNQQLEKKKNAqlLEEVRRREDSMVDNSQHL--QIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRI 862
Cdd:TIGR04523 356 SENSEKQRELEEKQNE--IEKLKKENQSYKQEIKNLesQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKE 433
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568987518 863 ERRKQLEEI---------LEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVHQLKQQ 924
Cdd:TIGR04523 434 TIIKNNSEIkdltnqdsvKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEE 504
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
441-650 |
1.34e-07 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 54.84 E-value: 1.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 441 KTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 520
Cdd:COG3883 22 QKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGS 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 521 LQDLT-----EEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtdssntdTALATLE 595
Cdd:COG3883 102 VSYLDvllgsESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELE-------AAKAELE 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 568987518 596 EALSEKERIIERLKEQRerddRERLEEIESFRKENKDLKEKVNALQAELTEKESS 650
Cdd:COG3883 175 AQQAEQEALLAQLSAEE----AAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
425-636 |
2.08e-07 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 55.02 E-value: 2.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 425 EEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLET----------LSNQNSDCKQHI--EVLKESLTAKEQR 492
Cdd:PHA02562 157 EDLLDISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTynknieeqrkKNGENIARKQNKydELVEEAKTIKAEI 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 493 AAiLQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE----------------IRDMKDMLEVKERKINVLQKKI 556
Cdd:PHA02562 237 EE-LTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVikmyekggvcptctqqISEGPDRITKIKDKLKELQHSL 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 557 ENL---QEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDrerlEEIESFRKENKDL 633
Cdd:PHA02562 316 EKLdtaIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNA----EELAKLQDELDKI 391
|
...
gi 568987518 634 KEK 636
Cdd:PHA02562 392 VKT 394
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
464-914 |
2.39e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 55.05 E-value: 2.39e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 464 KLETLSNQNSDCKQHIE-VLKESLTAKEQ-RAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDM 541
Cdd:PRK02224 163 KLEEYRERASDARLGVErVLSDQRGSLDQlKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEV 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 542 LEVKERK---INVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQ----TDSSNTDTALATLEEALSEKERIIERLKEQRER 614
Cdd:PRK02224 243 LEEHEERreeLETLEAEIEDLRETIAETEREREELAEEVRDLRerleELEEERDDLLAEAGLDDADAEAVEARREELEDR 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 615 DD--RERLEE----IESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNK 688
Cdd:PRK02224 323 DEelRDRLEEcrvaAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGD 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 689 LEAQLKkqaeqlfnqmynpahNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILK------EVENEK-- 760
Cdd:PRK02224 403 APVDLG---------------NAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqPVEGSPhv 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 761 ---NDKDKKIAELESLtLRHMKDQNKKVanlkyNQQLEKKKNAQLLEEVRRREDSMVDNSQHLqIEELMNALEKTRQELD 837
Cdd:PRK02224 468 etiEEDRERVEELEAE-LEDLEEEVEEV-----EERLERAEDLVEAEDRIERLEERREDLEEL-IAERRETIEEKRERAE 540
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568987518 838 ATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEalLAAISEKDANIALLELSASKKKKTQEEVMALkREK 914
Cdd:PRK02224 541 ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK--LAELKERIESLERIRTLLAAIADAEDEIERL-REK 614
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
383-618 |
2.47e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.00 E-value: 2.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 383 ALQTVIEMKDTKIASLERNIRDLEDEVQMLKANgvlnTEDREEEIKQIEvykshskfmkTKIDQLKQELSKKESELLALQ 462
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKE----EKALLKQLAALE----------RRIAALARRIRALEQELAALE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 463 TKLETLSNQNSDCKQHIEVLKESLtAKEQRAAILQTEVDALRLRLEEKESF-LNKKTKQLQDLTEEKGTLAGEIRDMKDM 541
Cdd:COG4942 83 AELAELEKEIAELRAELEAQKEEL-AELLRALYRLGRQPPLALLLSPEDFLdAVRRLQYLKYLAPARREQAEELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 542 LEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDR----VKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDR 617
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAALEALKAErqklLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
|
.
gi 568987518 618 E 618
Cdd:COG4942 242 R 242
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
519-772 |
2.51e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.92 E-value: 2.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 519 KQLQDLTEEkgtlageIRDMkdMLEVKErkinvLQKKIENLQEQLRDKD---KQLTNLKDRVKSLQtDSSNTDTALATLE 595
Cdd:COG4913 204 KPIGDLDDF-------VREY--MLEEPD-----TFEAADALVEHFDDLErahEALEDAREQIELLE-PIRELAERYAAAR 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 596 EALSEKERIIERLK-EQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEhasSLASAGLKRdskLKS 674
Cdd:COG4913 269 ERLAELEYLRAALRlWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEA---QIRGNGGDR---LEQ 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 675 LEIAIEQKKEECNKLEAQLKKQAEQLFNQMYNPAHNIEddsrmnpEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILK 754
Cdd:COG4913 343 LEREIERLERELEERERRRARLEALLAALGLPLPASAE-------EFAALRAEAAALLEALEEELEALEEALAEAEAALR 415
|
250
....*....|....*...
gi 568987518 755 EVENEKNDKDKKIAELES 772
Cdd:COG4913 416 DLRRELRELEAEIASLER 433
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
148-647 |
2.55e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.92 E-value: 2.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 148 LDLQAQLKELQRENDLLRKELDIKDSKLGssmnsiktfwspELKKERVLRKEEAARMSVLKEQMRVSHEENqllDARRTK 227
Cdd:COG4913 277 LRAALRLWFAQRRLELLEAELEELRAELA------------RLEAELERLEARLDALREELDELEAQIRGN---GGDRLE 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 228 HLQLTIQALQDELRTQRdlNHLLQQESGNRGAeHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLN 307
Cdd:COG4913 342 QLEREIERLERELEERE--RRRARLEALLAAL-GLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR 418
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 308 ARDESIKKLLEMLQSKGlpsKSLEDDNERTRRMAEAESQVS---------HLEVILDQK------EK------------- 359
Cdd:COG4913 419 RELRELEAEIASLERRK---SNIPARLLALRDALAEALGLDeaelpfvgeLIEVRPEEErwrgaiERvlggfaltllvpp 495
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 360 ----------ENIHLREELH------RRSQLQPEPAKTKALQTVIEMKDTKI-----ASLER--------NIRDLEDEVQ 410
Cdd:COG4913 496 ehyaaalrwvNRLHLRGRLVyervrtGLPDPERPRLDPDSLAGKLDFKPHPFrawleAELGRrfdyvcvdSPEELRRHPR 575
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 411 ------MLKANGVLNTEDREEEIKQIEVYKSHSKfmkTKIDQLKQELSKKESELLALQTKLETLsnqnsdcKQHIEVLKE 484
Cdd:COG4913 576 aitragQVKGNGTRHEKDDRRRIRSRYVLGFDNR---AKLAALEAELAELEEELAEAEERLEAL-------EAELDALQE 645
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 485 SLTAKEQRAAILQTEVD--ALRLRLEEKEsflnkktKQLQDLTEEKGTLAGeirdMKDMLEVKERKINVLQKKIENLQEQ 562
Cdd:COG4913 646 RREALQRLAEYSWDEIDvaSAEREIAELE-------AELERLDASSDDLAA----LEEQLEELEAELEELEEELDELKGE 714
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 563 LRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEkERIIERLKEQRERDDRERLEEiesfrkENKDLKEKVNALQA 642
Cdd:COG4913 715 IGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE-ERFAAALGDAVERELRENLEE------RIDALRARLNRAEE 787
|
....*
gi 568987518 643 ELTEK 647
Cdd:COG4913 788 ELERA 792
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
232-889 |
2.72e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 55.05 E-value: 2.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 232 TIQALQDELRTQR-DLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQK-QTLNAR 309
Cdd:TIGR00606 423 LKQEQADEIRDEKkGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLtETLKKE 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 310 DESIKKL-LEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELhrrSQLQPEPAKTKALQTVI 388
Cdd:TIGR00606 503 VKSLQNEkADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDEL---TSLLGYFPNKKQLEDWL 579
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 389 EMKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSH------SKFMKTKIDQLKQELSKKESELLALQ 462
Cdd:TIGR00606 580 HSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEESDLERLKEEIEKSSKQRAMLA 659
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 463 TK-------LETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEI 535
Cdd:TIGR00606 660 GAtavysqfITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSII 739
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 536 -RDMKDMLEVKERKINVlQKKIENLQEQLRDKDKQLTNLKDRVKS---LQTDSsntdTALATLEEALSEKERIIERL--- 608
Cdd:TIGR00606 740 dLKEKEIPELRNKLQKV-NRDIQRLKNDIEEQETLLGTIMPEEESakvCLTDV----TIMERFQMELKDVERKIAQQaak 814
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 609 --------------KEQRERDDRER--LEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHAS---SLASAGLKRD 669
Cdd:TIGR00606 815 lqgsdldrtvqqvnQEKQEKQHELDtvVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQrrqQFEEQLVELS 894
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 670 SKLKSLEIAIEQKKEECNKLEAQLKK---QAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEA-SYYRDECGKAQAE 745
Cdd:TIGR00606 895 TEVQSLIREIKDAKEQDSPLETFLEKdqqEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIeNKIQDGKDDYLKQ 974
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 746 VDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKYNQQLEKKKNAqlLEEVRRREDSMVDNSQHLQIEEL 825
Cdd:TIGR00606 975 KETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENE--LKEVEEELKQHLKEMGQMQVLQM 1052
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568987518 826 MNALEKTRQELDATKAR--LASTQQSLAEKEAHLANLRIeRRKQLEEILEMKQEALLAAISEKDAN 889
Cdd:TIGR00606 1053 KQEHQKLEENIDLIKRNhvLALGRQKGYEKEIKHFKKEL-REPQFRDAEEKYREMMIVMRTTELVN 1117
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
546-700 |
3.80e-07 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 52.23 E-value: 3.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 546 ERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQ-------RERDDRE 618
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQlgnvrnnKEYEALQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 619 RleEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASaglKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAE 698
Cdd:COG1579 96 K--EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEA---ELEEKKAELDEELAELEAELEELEAEREELAA 170
|
..
gi 568987518 699 QL 700
Cdd:COG1579 171 KI 172
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
521-666 |
4.65e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 53.71 E-value: 4.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 521 LQDLTEEKgtLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRdkdkqltNLKDRVKSLQTDssntdtaLATLEEALSE 600
Cdd:COG2433 382 LEELIEKE--LPEEEPEAEREKEHEERELTEEEEEIRRLEEQVE-------RLEAEVEELEAE-------LEEKDERIER 445
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568987518 601 KERIIERLKEQRERDDRERlEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGL 666
Cdd:COG2433 446 LERELSEARSEERREIRKD-REISRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGEL 510
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
217-745 |
4.78e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 54.15 E-value: 4.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 217 ENQLLDARR-TKHLQ------LTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELT--EENFRRLQAEHDRQAKELFL 287
Cdd:COG4913 241 HEALEDAREqIELLEpirelaERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEelRAELARLEAELERLEARLDA 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 288 LRKTLEEMELRIETQKqtlNARDESIKKLLEMLQskglpskslEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREE 367
Cdd:COG4913 321 LREELDELEAQIRGNG---GDRLEQLEREIERLE---------RELEERERRRARLEALLAALGLPLPASAEEFAALRAE 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 368 LHRRsqLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKANGVlNTEDREEEIKqievykshskfmktkiDQL 447
Cdd:COG4913 389 AAAL--LEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKS-NIPARLLALR----------------DAL 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 448 KQELSKKESEL-----------------LALQTKLETLS-----------------NQNSDcKQHIEVLKESLTAKEQRA 493
Cdd:COG4913 450 AEALGLDEAELpfvgelievrpeeerwrGAIERVLGGFAltllvppehyaaalrwvNRLHL-RGRLVYERVRTGLPDPER 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 494 AilQTEVDALRLRLEEKES----FLNKKTKQLQDL----------TEEKG-TLAGEIRDMKDMLE----VKERKINVL-- 552
Cdd:COG4913 529 P--RLDPDSLAGKLDFKPHpfraWLEAELGRRFDYvcvdspeelrRHPRAiTRAGQVKGNGTRHEkddrRRIRSRYVLgf 606
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 553 --QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDD-RERLEEIESFRKE 629
Cdd:COG4913 607 dnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAElEAELERLDASSDD 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 630 NKDLKEKVNALQAELTEKESSLIDLKEHASSLasaglkrDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLFNQMYNPAH 709
Cdd:COG4913 687 LAALEEQLEELEAELEELEEELDELKGEIGRL-------EKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAL 759
|
570 580 590
....*....|....*....|....*....|....*.
gi 568987518 710 NIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAE 745
Cdd:COG4913 760 GDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
168-860 |
5.51e-07 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 53.93 E-value: 5.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 168 LDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMsvLKEQMRVSHEENQLLdarRTKHLQLTIQALQDELRTQRDLN 247
Cdd:COG5022 714 IDSSKYQIGNTKVFFKAGVLAALEDMRDAKLDNIATR--IQRAIRGRYLRRRYL---QALKRIKKIQVIQHGFRLRRLVD 788
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 248 HLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKEL---FLLRKTLE-EMELRIETQKQTLnARDESIKKLLEMLQSK 323
Cdd:COG5022 789 YELKWRLFIKLQPLLSLLGSRKEYRSYLACIIKLQKTIkreKKLRETEEvEFSLKAEVLIQKF-GRSLKAKKRFSLLKKE 867
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 324 GLPSKS---LEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELH--RRSQLQPEPAKTKALQTVIEMKDTKIASl 398
Cdd:COG5022 868 TIYLQSaqrVELAERQLQELKIDVKSISSLKLVNLELESEIIELKKSLSsdLIENLEFKTELIARLKKLLNNIDLEEGP- 946
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 399 ERNIRDLEDEVQMLKANGVLN--TEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTK---LETLSNQNS 473
Cdd:COG5022 947 SIEYVKLPELNKLHEVESKLKetSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGALQEStkqLKELPVEVA 1026
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 474 DCKQHIEVLKESLTAKEQR-----------AAILQTEVDALRLRLEEKESFLNKKTKQLQDLTE--EKGTLAGEIRDMKD 540
Cdd:COG5022 1027 ELQSASKIISSESTELSILkplqklkglllLENNQLQARYKALKLRRENSLLDDKQLYQLESTEnlLKTINVKDLEVTNR 1106
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 541 MLEVKERKINVL---QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTA--LATLEEALSEKERIieRLKEQRERD 615
Cdd:COG5022 1107 NLVKPANVLQFIvaqMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLfwEANLEALPSPPPFA--ALSEKRLYQ 1184
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 616 DRERLEEIESFRKENKDLKEKVNAL----------QAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEE 685
Cdd:COG5022 1185 SALYDEKSKLSSSEVNDLKNELIALfskifsgwprGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSL 1264
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 686 CNKLEAQLKKQAEQ--LFNQMYNPAHNIEDDSRMNPEFAD----RLKQL-DKEASYYRDECGKAQAEVDRLLE------- 751
Cdd:COG5022 1265 LNSIDNLLSSYKLEeeVLPATINSLLQYINVGLFNALRTKasslRWKSAtEVNYNSEELDDWCREFEISDVDEeleeliq 1344
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 752 ---ILKEVENEKNDKDKKIAELESL---TLRHMKDQnKKVANLKYNqqLEKKKNAQLLEEVRRREDSMVDnsqhlqieEL 825
Cdd:COG5022 1345 avkVLQLLKDDLNKLDELLDACYSLnpaEIQNLKSR-YDPADKENN--LPKEILKKIEALLIKQELQLSL--------EG 1413
|
730 740 750
....*....|....*....|....*....|....*
gi 568987518 826 MNALEKTRQELDATKARLASTQQSLAEKEAHLANL 860
Cdd:COG5022 1414 KDETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSL 1448
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
518-700 |
6.04e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.84 E-value: 6.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 518 TKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEA 597
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 598 LSE-KERIIERLKEQRERDDRERLEEIES-------------FRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLAS 663
Cdd:COG4942 99 LEAqKEELAELLRALYRLGRQPPLALLLSpedfldavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178
|
170 180 190
....*....|....*....|....*....|....*..
gi 568987518 664 AGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQL 700
Cdd:COG4942 179 LLAELEEERAALEALKAERQKLLARLEKELAELAAEL 215
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
314-935 |
6.25e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 53.82 E-value: 6.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 314 KKLLEMLQSKglpsKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDT 393
Cdd:pfam02463 176 KKLIEETENL----AELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQE 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 394 KIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNS 473
Cdd:pfam02463 252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 474 DCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQ 553
Cdd:pfam02463 332 KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 554 KKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTaLATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDL 633
Cdd:pfam02463 412 ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLT-EEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 634 KEKV---------------NALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAE 698
Cdd:pfam02463 491 SRQKleersqkeskarsglKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 699 QLFNQMYNPAHNIEDDSRMN------PEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELE- 771
Cdd:pfam02463 571 TELPLGARKLRLLIPKLKLPlksiavLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRk 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 772 ---------SLTLRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATK-- 840
Cdd:pfam02463 651 gvsleeglaEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQea 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 841 -----ARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD 915
Cdd:pfam02463 731 qdkinEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEEL 810
|
650 660
....*....|....*....|
gi 568987518 916 RLVHQLKQQVGRPARQTQNR 935
Cdd:pfam02463 811 KEEAELLEEEQLLIEQEEKI 830
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
281-532 |
8.42e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.46 E-value: 8.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 281 QAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLqskglpsKSLEDD-NERTRRMAEAESQVSHLEVILDQKEK 359
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL-------AALERRiAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 360 ENIHLREELHRRSQLQpepakTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREeeikQIEVYKSHSKF 439
Cdd:COG4942 91 EIAELRAELEAQKEEL-----AELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----QAEELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 440 MKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE--EKESFLNKK 517
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIArlEAEAAAAAE 241
|
250
....*....|....*
gi 568987518 518 TKQLQDLTEEKGTLA 532
Cdd:COG4942 242 RTPAAGFAALKGKLP 256
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
441-850 |
9.83e-07 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 52.82 E-value: 9.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 441 KTKIDQLKQELSKK-----------ESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEE 509
Cdd:pfam05557 8 KARLSQLQNEKKQMelehkrarielEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 510 KESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT 589
Cdd:pfam05557 88 LNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 590 A---LATLEEALSEKERIIERLKEQRERDDR--------ERLEEIESFRKENKD----LKEKVNALQAELTEKEssliDL 654
Cdd:pfam05557 168 AeqrIKELEFEIQSQEQDSEIVKNSKSELARipelekelERLREHNKHLNENIEnkllLKEEVEDLKRKLEREE----KY 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 655 KEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAqLKKQAEQLfnQMYNPAHNIEDDSRMNpefadRLKQLDKEASY 734
Cdd:pfam05557 244 REEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPED-LSRRIEQL--QQREIVLKEENSSLTS-----SARQLEKARRE 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 735 YRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELEsltlrhmKDQNKKVANLK-YNQQLEKKKNAQLLEEVRRREDSM 813
Cdd:pfam05557 316 LEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLT-------KERDGYRAILEsYDKELTMSNYSPQLLERIEEAEDM 388
|
410 420 430
....*....|....*....|....*....|....*..
gi 568987518 814 VDNSQhLQIEELMNALEKTRQELDATKARLASTQQSL 850
Cdd:pfam05557 389 TQKMQ-AHNEEMEAQLSVAEEELGGYKQQAQTLEREL 424
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
440-639 |
1.08e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 51.08 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 440 MKTKIDQLKqELSKKESELLALQTKLETLsnqnsdcKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLnkktK 519
Cdd:COG1579 2 MPEDLRALL-DLQELDSELDRLEHRLKEL-------PAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEI----E 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 520 QLQDLTEEKGTLAGEIRDMKDMlevkerkiNVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtdssntdTALATLEEALS 599
Cdd:COG1579 70 EVEARIKKYEEQLGNVRNNKEY--------EALQKEIESLKRRISDLEDEILELMERIEELE-------EELAELEAELA 134
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 568987518 600 EKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNA 639
Cdd:COG1579 135 ELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPP 174
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
760-877 |
1.10e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.47 E-value: 1.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 760 KNDKDKKIAELESLTLRHMKDQNKKVANLKYNQQLE-----KKKNAQLLEEVRRREDSMVDNSQHLQIEEL-----MNAL 829
Cdd:PRK12704 26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEakeeiHKLRNEFEKELRERRNELQKLEKRLLQKEEnldrkLELL 105
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 568987518 830 EKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQE 877
Cdd:PRK12704 106 EKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAE 153
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
151-834 |
1.52e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 52.36 E-value: 1.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 151 QAQLKELQRENDLLRKELDIKDSKLGSSMNS----IKTFWSPELKKERVLRKEEAARMSvlkEQMRVSHEENQLLDARRT 226
Cdd:TIGR00606 425 QEQADEIRDEKKGLGRTIELKKEILEKKQEElkfvIKELQQLEGSSDRILELDQELRKA---ERELSKAEKNSLTETLKK 501
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 227 KHLQLTIQALqDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKqTL 306
Cdd:TIGR00606 502 EVKSLQNEKA-DLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLED-WL 579
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 307 NARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEA-ESQVSHLEVIL------DQKEKENIHLREELHR-RSQLQPEP 378
Cdd:TIGR00606 580 HSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESkEEQLSSYEDKLfdvcgsQDEESDLERLKEEIEKsSKQRAMLA 659
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 379 AKTKALQTVIEMKDTKIAS-------LERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQEL 451
Cdd:TIGR00606 660 GATAVYSQFITQLTDENQSccpvcqrVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSII 739
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 452 SKKESELLALQTKLETLSNQNSDCKQHI---EVLKESLTAKEQRAAILQTEV---DALRLRLEEKESFLNKKTKQLQ--D 523
Cdd:TIGR00606 740 DLKEKEIPELRNKLQKVNRDIQRLKNDIeeqETLLGTIMPEEESAKVCLTDVtimERFQMELKDVERKIAQQAAKLQgsD 819
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 524 LTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKER 603
Cdd:TIGR00606 820 LDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQS 899
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 604 IIERLKEQR----------ERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKrdsklk 673
Cdd:TIGR00606 900 LIREIKDAKeqdspletflEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLK------ 973
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 674 sleiaieQKKEECNKLEAQLKKQAEQlfnqmynpAHNIEDDSrmnpefadRLKQLDKEASYYRDECGKAQAEVDRLLEIL 753
Cdd:TIGR00606 974 -------QKETELNTVNAQLEECEKH--------QEKINEDM--------RLMRQDIDTQKIQERWLQDNLTLRKRENEL 1030
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 754 KEVENEKNDKDKKIAELESLtlrHMKDQNKKVANlkyNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTR 833
Cdd:TIGR00606 1031 KEVEEELKQHLKEMGQMQVL---QMKQEHQKLEE---NIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEKYR 1104
|
.
gi 568987518 834 Q 834
Cdd:TIGR00606 1105 E 1105
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
546-731 |
2.11e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.84 E-value: 2.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 546 ERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQ---------TDSSNTDTALATLEEALSEKERIIERLKE------ 610
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQerrealqrlAEYSWDEIDVASAEREIAELEAELERLDAssddla 688
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 611 --QRERDDRErlEEIESFRKENKDLKEKVNALQAELTEKESSLIDLK---EHASSLASAGL---------------KRDS 670
Cdd:COG4913 689 alEEQLEELE--AELEELEEELDELKGEIGRLEKELEQAEEELDELQdrlEAAEDLARLELralleerfaaalgdaVERE 766
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568987518 671 KLKSLEIAIEQKKEECNKLEAQLKKQAEQlFNQMY-NPAHNIEDDSRMNPEFADRLKQLDKE 731
Cdd:COG4913 767 LRENLEERIDALRARLNRAEEELERAMRA-FNREWpAETADLDADLESLPEYLALLDRLEED 827
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
273-565 |
2.70e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 2.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 273 RLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEddnertRRMAEAESQVSHLEV 352
Cdd:TIGR02169 692 SLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE------QEIENVKSELKELEA 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 353 ILDQKEKENIHLREELH------RRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRD-------LEDEVQMLKANgVLN 419
Cdd:TIGR02169 766 RIEELEEDLHKLEEALNdlearlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRltlekeyLEKEIQELQEQ-RID 844
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 420 TEDREEEIKQievykshskfmktKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTE 499
Cdd:TIGR02169 845 LKEQIKSIEK-------------EIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568987518 500 VDALRLRLEEKESflnkktkQLQDLTEEKGTLAGEIRDMKDMLEvKERKINVLQKKIENLQEQLRD 565
Cdd:TIGR02169 912 IEKKRKRLSELKA-------KLEALEEELSEIEDPKGEDEEIPE-EELSLEDVQAELQRVEEEIRA 969
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
145-613 |
2.74e-06 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 51.28 E-value: 2.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 145 STMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMrvshEENQLLdar 224
Cdd:pfam05557 9 ARLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQA----ELNRLK--- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 225 rTKHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRI---ET 301
Cdd:pfam05557 82 -KKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRqnlEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 302 QKQTLNARDESIKKLLEMLQSKglpskslEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKT 381
Cdd:pfam05557 161 QQSSLAEAEQRIKELEFEIQSQ-------EQDSEIVKNSKSELARIPELEKELERLREHNKHLNENIENKLLLKEEVEDL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 382 KALQTVIEMKDTKIASLERNIRDLEDEVQM---LKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESEL 458
Cdd:pfam05557 234 KRKLEREEKYREEAATLELEKEKLEQELQSwvkLAQDTGLNLRSPEDLSRRIEQLQQREIVLKEENSSLTSSARQLEKAR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 459 LALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNkKTKQLQDLTEEKGTLAGEIRDM 538
Cdd:pfam05557 314 RELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESYDKELT-MSNYSPQLLERIEEAEDMTQKM 392
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568987518 539 KDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDrvKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRE 613
Cdd:pfam05557 393 QAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQ--QESLADPSYSKEEVDSLRRKLETLELERQRLREQKN 465
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
376-727 |
3.84e-06 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 50.73 E-value: 3.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 376 PEPAKTKALQTVIEMKDTKIASLerNIRDLEDEVQMLKANGVLntEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKE 455
Cdd:COG5185 198 AEPSGTVNSIKESETGNLGSEST--LLEKAKEIINIEEALKGF--QDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGEN 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 456 SEllalqtKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQT--EVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAG 533
Cdd:COG5185 274 AE------SSKRLNENANNLIKQFENTKEKIAEYTKSIDIKKAteSLEEQLAAAEAEQELEESKRETETGIQNLTAEIEQ 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 534 EIRDMKDMLEV--KERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSN-TDTALATLEEALSEKERIIERLKE 610
Cdd:COG5185 348 GQESLTENLEAikEEIENIVGEVELSKSSEELDSFKDTIESTKESLDEIPQNQRGyAQEILATLEDTLKAADRQIEELQR 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 611 QRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSliDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLE 690
Cdd:COG5185 428 QIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEE--AYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLR 505
|
330 340 350
....*....|....*....|....*....|....*..
gi 568987518 691 AQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQ 727
Cdd:COG5185 506 AKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALE 542
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
354-603 |
4.55e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.15 E-value: 4.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 354 LDQKEKENIHLREELHR-RSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEVQMLkangvlntedrEEEIKQIEv 432
Cdd:COG4942 22 AAEAEAELEQLQQEIAElEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAAL-----------EAELAELE- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 433 ykshskfmkTKIDQLKQELSKKESELLALQTKLETLSNQNSdckqhIEVL--KESLTAKEQRAAILQTEVDALRLRLEEk 510
Cdd:COG4942 90 ---------KEIAELRAELEAQKEELAELLRALYRLGRQPP-----LALLlsPEDFLDAVRRLQYLKYLAPARREQAEE- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 511 esfLNKKTKQLQDLTEEkgtLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTA 590
Cdd:COG4942 155 ---LRADLAELAALRAE---LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
250
....*....|...
gi 568987518 591 LATLEEALSEKER 603
Cdd:COG4942 229 IARLEAEAAAAAE 241
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
388-648 |
5.14e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.68 E-value: 5.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 388 IEMKDTKIASLERNIRDLEDEVQMLKANgVLNTEDREEEIKQIEVYKSHSKFMKT---KIDQLKQELSKKE---SELLAL 461
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLEALEAE-LDALQERREALQRLAEYSWDEIDVASaerEIAELEAELERLDassDDLAAL 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 462 QTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFlnKKTKQLQDLTEEKGTLAGEiRDMKDM 541
Cdd:COG4913 691 EEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDL--ARLELRALLEERFAAALGD-AVEREL 767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 542 LEVKERKINVLQKKIENLQEQLRDKdkqltnLKDRVKSLQTDSSNTDTALATLEEALSEKERII--------ERLKEQRE 613
Cdd:COG4913 768 RENLEERIDALRARLNRAEEELERA------MRAFNREWPAETADLDADLESLPEYLALLDRLEedglpeyeERFKELLN 841
|
250 260 270
....*....|....*....|....*....|....*.
gi 568987518 614 RDDRERLEEIES-FRKENKDLKEKVNALQAELTEKE 648
Cdd:COG4913 842 ENSIEFVADLLSkLRRAIREIKERIDPLNDSLKRIP 877
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
573-832 |
5.28e-06 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 50.40 E-value: 5.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 573 LKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQrERDDRERLEE-IESFRKENKDLKEKVNALQAELTEKESSL 651
Cdd:PHA02562 172 NKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKK-NGENIARKQNkYDELVEEAKTIKAEIEELTDELLNLVMDI 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 652 IDLKEHAsslasaglkrdSKLKSLEIAIEQKKEECNKLEAQLKKQAEqlfnqmyNPA--HNIEDDSRMNPEFADRLKQLD 729
Cdd:PHA02562 251 EDPSAAL-----------NKLNTAAAKIKSKIEQFQKVIKMYEKGGV-------CPTctQQISEGPDRITKIKDKLKELQ 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 730 KEASyyrdecgkaqaEVDRLLEILKEVENEKNDKDKKIAELesltlrhmkdqNKKVANLKYNQQLEKKKNAQLLEEVRRR 809
Cdd:PHA02562 313 HSLE-----------KLDTAIDELEEIMDEFNEQSKKLLEL-----------KNKISTNKQSLITLVDKAKKVKAAIEEL 370
|
250 260
....*....|....*....|...
gi 568987518 810 EDSMVDNSQhlQIEELMNALEKT 832
Cdd:PHA02562 371 QAEFVDNAE--ELAKLQDELDKI 391
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
391-698 |
5.77e-06 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 50.82 E-value: 5.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 391 KDTKIASLERNIRDLEDEVQMLKA--NGVLNT-----EDREEEIKQIEvYKSHSKFMKTKIDQLKQELSKKESELLALQT 463
Cdd:PTZ00108 997 KEYLLGKLERELARLSNKVRFIKHviNGELVItnakkKDLVKELKKLG-YVRFKDIIKKKSEKITAEEEEGAEEDDEADD 1075
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 464 KLETLSNQNSDC-------------KQHIEVLKESLTAKEQRAAILQ---------TEVDALRLRLEEKESFLNKKTKQL 521
Cdd:PTZ00108 1076 EDDEEELGAAVSydyllsmpiwsltKEKVEKLNAELEKKEKELEKLKnttpkdmwlEDLDKFEEALEEQEEVEEKEIAKE 1155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 522 QDLTEEKGTLAGEIRDMKDMLEVKERKIN----------VLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTAL 591
Cdd:PTZ00108 1156 QRLKSKTKGKASKLRKPKLKKKEKKKKKSsadkskkasvVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKP 1235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 592 ATLEEALSEKERIIERLKEQRERDDRERLEEIESFRkenKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSK 671
Cdd:PTZ00108 1236 KKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKP---KNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVKK 1312
|
330 340
....*....|....*....|....*...
gi 568987518 672 -LKSLEIAIEQKKEECNKLEAQLKKQAE 698
Cdd:PTZ00108 1313 rLEGSLAALKKKKKSEKKTARKKKSKTR 1340
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
440-738 |
7.69e-06 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 49.52 E-value: 7.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 440 MKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTK 519
Cdd:COG4372 43 LQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQK 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 520 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKD-----RVKSLQTDSSNTDTALATL 594
Cdd:COG4372 123 ERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEaeaeqALDELLKEANRNAEKEEEL 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 595 EEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKS 674
Cdd:COG4372 203 AEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAA 282
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568987518 675 LEIAIEQKKEECNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDE 738
Cdd:COG4372 283 LELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLL 346
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
389-821 |
1.30e-05 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 49.66 E-value: 1.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 389 EMKDTKIASLERNIRDLEDEVQMLkangvlnTEDREEEIKQIEVYKSHSKFMKTkIDQLKQELSKKESEllalQTKLETL 468
Cdd:TIGR01612 879 EISDDKLNDYEKKFNDSKSLINEI-------NKSIEEEYQNINTLKKVDEYIKI-CENTKESIEKFHNK----QNILKEI 946
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 469 SNQNSDCKQHIEVLKESLTAKEQRAAILQ-TEVDAL--RLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIrdMKDMLEVK 545
Cdd:TIGR01612 947 LNKNIDTIKESNLIEKSYKDKFDNTLIDKiNELDKAfkDASLNDYEAKNNELIKYFNDLKANLGKNKENM--LYHQFDEK 1024
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 546 ERKINVLQKKIENLQEQLRDKD----KQLTNLKDRVKSL---QTDSSNTDTaLATLEEALSEKERIIERLKEQRERD--- 615
Cdd:TIGR01612 1025 EKATNDIEQKIEDANKNIPNIEiaihTSIYNIIDEIEKEigkNIELLNKEI-LEEAEINITNFNEIKEKLKHYNFDDfgk 1103
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 616 --DRERLEEIESFRKENKDLKEKVNALQAELTE----KESSLIDLKEHASSLASAGLKR---------DSKLKSLEIAIE 680
Cdd:TIGR01612 1104 eeNIKYADEINKIKDDIKNLDQKIDHHIKALEEikkkSENYIDEIKAQINDLEDVADKAisnddpeeiEKKIENIVTKID 1183
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 681 QKK---EECNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVE 757
Cdd:TIGR01612 1184 KKKniyDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIE 1263
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568987518 758 NEKNDKDKKIAELESLTLRHMKDQNKKVANLKYNQQLEKKKNAQL-LEEVRRREDSMVDNSQHLQ 821
Cdd:TIGR01612 1264 NEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKSLkIIEDFSEESDINDIKKELQ 1328
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
495-922 |
1.42e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.29 E-value: 1.42e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 495 ILQTEVDALRLRLEEKESFLnKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKInvlqKKIENLQEQLRDKDKQLTNLK 574
Cdd:PRK03918 132 IRQGEIDAILESDESREKVV-RQILGLDDYENAYKNLGEVIKEIKRRIERLEKFI----KRTENIEELIKEKEKELEEVL 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 575 DRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQR-------------ERDDRERLEEIESFRKENKDLKEKVNALQ 641
Cdd:PRK03918 207 REINEISSELPELREELEKLEKEVKELEELKEEIEELEkeleslegskrklEEKIRELEERIEELKKEIEELEEKVKELK 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 642 A--ELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKqAEQLFNQMYNPAHNIEDDSRMnp 719
Cdd:PRK03918 287 ElkEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHEL-- 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 720 efADRLKQLDKEASYYRDEcgKAQAEVDRLLEILKEVENEKNDKDKKIAELEsltlRHMKDQNKKVANLKYNqqLEKKKN 799
Cdd:PRK03918 364 --YEEAKAKKEELERLKKR--LTGLTPEKLEKELEELEKAKEEIEEEISKIT----ARIGELKKEIKELKKA--IEELKK 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 800 AQLLEEVRRREdsmvdnsqhLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEAL 879
Cdd:PRK03918 434 AKGKCPVCGRE---------LTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQ 504
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 568987518 880 LAAISEKDANIALLELSASKKK--KTQEEVMALKREKDRLVHQLK 922
Cdd:PRK03918 505 LKELEEKLKKYNLEELEKKAEEyeKLKEKLIKLKGEIKSLKKELE 549
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
187-877 |
1.46e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 49.20 E-value: 1.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 187 SPELKKERVLRKEEAARMSVLKEQMRVSHEENQLLDARRTKHLqltIQALQDELRTQRDLNHL--LQQESGNRGAEHFTI 264
Cdd:TIGR00618 189 KKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHL---REALQQTQQSHAYLTQKreAQEEQLKKQQLLKQL 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 265 ELTEENFRRLQAEHDRQAKELFLLRKTLEEME-----LRIETQKQTLNARDESIKKLLEmlqskglpsKSLEDDNERTRR 339
Cdd:TIGR00618 266 RARIEELRAQEAVLEETQERINRARKAAPLAAhikavTQIEQQAQRIHTELQSKMRSRA---------KLLMKRAAHVKQ 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 340 MAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKT---KALQTVIEMKDTKIASLERNIRDLEDEVqmlkanG 416
Cdd:TIGR00618 337 QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTqhiHTLQQQKTTLTQKLQSLCKELDILQREQ------A 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 417 VLNTEDREEEIKQIEVYKSHSKF-MKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRaai 495
Cdd:TIGR00618 411 TIDTRTSAFRDLQGQLAHAKKQQeLQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETR--- 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 496 LQTEVDALRLRLEEKESFLNKKTKQLqdltEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKD 575
Cdd:TIGR00618 488 KKAVVLARLLELQEEPCPLCGSCIHP----NPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKE 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 576 RVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTE--KESSLID 653
Cdd:TIGR00618 564 QMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLqqCSQELAL 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 654 LKEHASSLASAGLKRDSKLKSLEIAiEQKKEECNKLEAQLKKqAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEAS 733
Cdd:TIGR00618 644 KLTALHALQLTLTQERVREHALSIR-VLPKELLASRQLALQK-MQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFN 721
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 734 YYRDECGKAQAEVDRLLEILKEVENEKNDKDKkiaelESLTLRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSM 813
Cdd:TIGR00618 722 EIENASSSLGSDLAAREDALNQSLKELMHQAR-----TVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREE 796
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568987518 814 VDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQE 877
Cdd:TIGR00618 797 DTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQ 860
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
501-767 |
1.97e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 48.74 E-value: 1.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 501 DALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKK----IENLQEQLRDKDKqltnLKDR 576
Cdd:PLN02939 96 DHNRASMQRDEAIAAIDNEQQTNSKDGEQLSDFQLEDLVGMIQNAEKNILLLNQArlqaLEDLEKILTEKEA----LQGK 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 577 VKSLQTDSSNTDTALAtleeaLSEKERI-IERLKEQRERDDRERL--------------EEIESFRKENKDLKEKVNALQ 641
Cdd:PLN02939 172 INILEMRLSETDARIK-----LAAQEKIhVEILEEQLEKLRNELLirgateglcvhslsKELDVLKEENMLLKDDIQFLK 246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 642 AELT------------EKESSLID--LKEHASSLASAglKRD-SKLKSLEI-AIEQKKEECNKLEAQLKKQAEQlfnqmy 705
Cdd:PLN02939 247 AELIevaeteervfklEKERSLLDasLRELESKFIVA--QEDvSKLSPLQYdCWWEKVENLQDLLDRATNQVEK------ 318
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568987518 706 npAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKaqaeVDRLLEILKEVENEKNDKDKKI 767
Cdd:PLN02939 319 --AALVLDQNQDLRDKVDKLEASLKEANVSKFSSYK----VELLQQKLKLLEERLQASDHEI 374
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
556-770 |
2.28e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 48.39 E-value: 2.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 556 IENLQE----QLRDKDKQLTNLKDR-VKSLQTDSSNtdtALATLEEALSEKERIIERLKEQRERDdrerLEEIEsfrken 630
Cdd:PRK05771 22 LEALHElgvvHIEDLKEELSNERLRkLRSLLTKLSE---ALDKLRSYLPKLNPLREEKKKVSVKS----LEELI------ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 631 KDLKEKVNALQAELTEKESSLIDLKEHASSLaSAGLKRDSKLKSLEIAIEQKKEECN------KLEAQLKKQAEQLFNQM 704
Cdd:PRK05771 89 KDVEEELEKIEKEIKELEEEISELENEIKEL-EQEIERLEPWGNFDLDLSLLLGFKYvsvfvgTVPEDKLEELKLESDVE 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568987518 705 YnpAHNIEDDSRMNP-------EFADRLKQLDKEASYYR---DECGKAQAEVDRLLEILKEVENEKNDKDKKIAEL 770
Cdd:PRK05771 168 N--VEYISTDKGYVYvvvvvlkELSDEVEEELKKLGFERlelEEEGTPSELIREIKEELEEIEKERESLLEELKEL 241
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
508-905 |
4.55e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 47.41 E-value: 4.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 508 EEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNT 587
Cdd:pfam05483 229 EEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRS 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 588 DTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLK 667
Cdd:pfam05483 309 MSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQK 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 668 RDSKLKSLEIAIEQKKEECNKLEAQLKKQaEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVD 747
Cdd:pfam05483 389 KSSELEEMTKFKNNKEVELEELKKILAED-EKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEE 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 748 RLLEILKEVENEKNDKDKKIAELESlTLRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEE--L 825
Cdd:pfam05483 468 HYLKEVEDLKTELEKEKLKNIELTA-HCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEmnL 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 826 MNALEKTRQEL----DATKARLASTqqslaEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALL--ELSASK 899
Cdd:pfam05483 547 RDELESVREEFiqkgDEVKCKLDKS-----EENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELhqENKALK 621
|
....*.
gi 568987518 900 KKKTQE 905
Cdd:pfam05483 622 KKGSAE 627
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
490-703 |
4.82e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.60 E-value: 4.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 490 EQRAAILQTEVDALRlRLEEKESFLNKKTKQLQDLTE------EKGTLAGEIRDMKDMLEV--KERKINVLQKKIENLQE 561
Cdd:COG4913 224 FEAADALVEHFDDLE-RAHEALEDAREQIELLEPIRElaeryaAARERLAELEYLRAALRLwfAQRRLELLEAELEELRA 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 562 QLRDkdkqltnlkdrvkslqtdssnTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIEsfrKENKDLKEKVNALQ 641
Cdd:COG4913 303 ELAR---------------------LEAELERLEARLDALREELDELEAQIRGNGGDRLEQLE---REIERLERELEERE 358
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568987518 642 AELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLFNQ 703
Cdd:COG4913 359 RRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
289-624 |
5.16e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 47.37 E-value: 5.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 289 RKTLEEMELRIETQKQTLNARDESIKKLLEMLQS---KGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLR 365
Cdd:PRK03918 400 KEEIEEEISKITARIGELKKEIKELKKAIEELKKakgKCPVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLR 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 366 EELHR-RSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEVQML-KANGVLNT-----EDREEEIKQIEVYKSHSK 438
Cdd:PRK03918 480 KELRElEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYeKLKEKLIKlkgeiKSLKKELEKLEELKKKLA 559
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 439 FMKTKIDQLKQELSKKESELLALQTKL-----ETLSNQNSDCKQHIEVL--KESLTAKEQRAAILQTEVDALRLRLEEKE 511
Cdd:PRK03918 560 ELEKKLDELEEELAELLKELEELGFESveeleERLKELEPFYNEYLELKdaEKELEREEKELKKLEEELDKAFEELAETE 639
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 512 SFLNKKTKQLQDLteEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLqtdsSNTDTAL 591
Cdd:PRK03918 640 KRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER----EKAKKEL 713
|
330 340 350
....*....|....*....|....*....|...
gi 568987518 592 ATLEEALSEKERIIERLKEQRERDDRERLEEIE 624
Cdd:PRK03918 714 EKLEKALERVEELREKVKKYKALLKERALSKVG 746
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
428-745 |
7.24e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 46.66 E-value: 7.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 428 KQIEVYKSHSKFMKTKIDQLKQELSKKESELlALQTKLEtlsnqNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRL 507
Cdd:pfam17380 282 KAVSERQQQEKFEKMEQERLRQEKEEKAREV-ERRRKLE-----EAEKARQAEMDRQAAIYAEQERMAMERERELERIRQ 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 508 EEKEsflnkktKQLQDLTEEKgtLAGEIRDMKDMlevkERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNT 587
Cdd:pfam17380 356 EERK-------RELERIRQEE--IAMEISRMREL----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEM 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 588 DTALATLEEALS------------EKERIieRLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLK 655
Cdd:pfam17380 423 EQIRAEQEEARQrevrrleeerarEMERV--RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKE 500
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 656 EHASSlaSAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYY 735
Cdd:pfam17380 501 LEERK--QAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMM 578
|
330
....*....|..
gi 568987518 736 RD--ECGKAQAE 745
Cdd:pfam17380 579 RQivESEKARAE 590
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
438-641 |
7.50e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 46.69 E-value: 7.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 438 KFMKTKIDQLKQELSK--KESELLALQTKLETLSNQnsdcKQHIEVLKESLtakEQRAAILQTEVDALRLRLEEKESFLN 515
Cdd:PRK12704 27 KIAEAKIKEAEEEAKRilEEAKKEAEAIKKEALLEA----KEEIHKLRNEF---EKELRERRNELQKLEKRLLQKEENLD 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 516 KKTKQLQDLTEEkgtlageIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLkdrvkslqtdssntdtalaTLE 595
Cdd:PRK12704 100 RKLELLEKREEE-------LEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGL-------------------TAE 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 568987518 596 EAlseKERIIERLKEQRERDDRERLEEIESFRKENKDLKEK---VNALQ 641
Cdd:PRK12704 154 EA---KEILLEKVEEEARHEAAVLIKEIEEEAKEEADKKAKeilAQAIQ 199
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
743-930 |
9.57e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.60 E-value: 9.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 743 QAEVDRLLEILKEVENEKNDKDKKIAELESLtlrhMKDQNKKVANLKYNQQLE-KKKNAQLLEEVRRREDSMVDNSQhlQ 821
Cdd:TIGR02169 243 ERQLASLEEELEKLTEEISELEKRLEEIEQL----LEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKER--E 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 822 IEELMNALEKTRQELDATKARLASTQQSLAEKeahlanlRIERRKQLEEILEMKQE--ALLAAISEKDANIALL--ELSA 897
Cdd:TIGR02169 317 LEDAEERLAKLEAEIDKLLAEIEELEREIEEE-------RKRRDKLTEEYAELKEEleDLRAELEEVDKEFAETrdELKD 389
|
170 180 190
....*....|....*....|....*....|....*
gi 568987518 898 SKKK--KTQEEVMALKREKDRLVHQLKQQVGRPAR 930
Cdd:TIGR02169 390 YREKleKLKREINELKRELDRLQEELQRLSEELAD 424
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
658-906 |
1.03e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 658 ASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLFNQmynpahnieddsrmnpefADRLKQLDKEASYYRD 737
Cdd:COG4942 15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL------------------ERRIAALARRIRALEQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 738 ECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRhMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRRedsmvDNS 817
Cdd:COG4942 77 ELAALEAELAELEKEIAELRAELEAQKEELAELLRALYR-LGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA-----RRE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 818 QHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEiLEMKQEALLAAISEKDANIALLELSA 897
Cdd:COG4942 151 QAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLAR-LEKELAELAAELAELQQEAEELEALI 229
|
....*....
gi 568987518 898 SKKKKTQEE 906
Cdd:COG4942 230 ARLEAEAAA 238
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
339-873 |
1.15e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 46.32 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 339 RMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKA-LQTVIEMKDTKIASLERNIRDLEDEVQML---KA 414
Cdd:pfam01576 20 RQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRArLAARKQELEEILHELESRLEEEEERSQQLqneKK 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 415 NGVLNTEDREEEIKQIEVYKSHSKFMKTKIDqlkQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAA 494
Cdd:pfam01576 100 KMQQHIQDLEEQLDEEEAARQKLQLEKVTTE---AKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAK 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 495 ILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDmlevkerKINVLQKKIENLQEQLRDKDKQLTNLK 574
Cdd:pfam01576 177 SLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQE-------QIAELQAQIAELRAQLAKKEEELQAAL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 575 DRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERL---EEIESFRKENKDLKEKVNALQAELTEKESSL 651
Cdd:pfam01576 250 ARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRdlgEELEALKTELEDTLDTTAAQQELRSKREQEV 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 652 IDLKE--------HASSLASAGLKRDSKLKSLEIAIEQKKEECNKLE----------AQLKKQAEQLFNQMYNPAHNIED 713
Cdd:pfam01576 330 TELKKaleeetrsHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEkakqalesenAELQAELRTLQQAKQDSEHKRKK 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 714 DSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESltlrHMKD-----QNKKVANL 788
Cdd:pfam01576 410 LEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES----QLQDtqellQEETRQKL 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 789 KYN---QQLEKKKNAqLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERR 865
Cdd:pfam01576 486 NLStrlRQLEDERNS-LQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEK 564
|
....*...
gi 568987518 866 KQLEEILE 873
Cdd:pfam01576 565 AAAYDKLE 572
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
346-840 |
1.16e-04 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 46.58 E-value: 1.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 346 QVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIE-----MKDTKIASLERNIRDLEDEvqmlKANGVLNT 420
Cdd:TIGR01612 407 KLKHLEILYKHQEDILNNFHKTIERLIFEKPDPNNNNIFKDDFDefnkpIPKSKLKALEKRFFEIFEE----EWGSYDIK 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 421 EDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLAlQTKLETLSNQNSDCKQHIEV---LKESLT-AKEQRAAIL 496
Cdd:TIGR01612 483 KDIDENSKQDNTVKLILMRMKDFKDIIDFMELYKPDEVPS-KNIIGFDIDQNIKAKLYKEIeagLKESYElAKNWKKLIH 561
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 497 QtevdaLRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDM-LEVKErkinvlqkKIENLQeqlrDKDKQLTNLKD 575
Cdd:TIGR01612 562 E-----IKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYINKLkLELKE--------KIKNIS----DKNEYIKKAID 624
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 576 RVKSLQTDSSNTD----TALATLEEALSEKERIIERLKEQRER---DDRERL-EEIESFRKENK----DLKEKVNALQAE 643
Cdd:TIGR01612 625 LKKIIENNNAYIDelakISPYQVPEHLKNKDKIYSTIKSELSKiyeDDIDALyNELSSIVKENAidntEDKAKLDDLKSK 704
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 644 LtEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPEFAD 723
Cdd:TIGR01612 705 I-DKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNK 783
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 724 RLKQLDKEASYYRDECG-------KAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVaNLKYN----- 791
Cdd:TIGR01612 784 YKSKISEIKNHYNDQINidnikdeDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFI-NFENNckeki 862
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 568987518 792 -------QQLEKKKNAQLLEEVRRREDSMVDNSQHLqIEELMNALEKTRQELDATK 840
Cdd:TIGR01612 863 dseheqfAELTNKIKAEISDDKLNDYEKKFNDSKSL-INEINKSIEEEYQNINTLK 917
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
269-937 |
1.35e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 46.19 E-value: 1.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 269 ENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKglpSKSLEDDNERTRRMAEAESQVS 348
Cdd:TIGR00606 189 ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSY---ENELDPLKNRLKEIEHNLSKIM 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 349 HLE---VILDQKEKENIHLREELHRRsQLQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEVqmlkanGVLNTEDREE 425
Cdd:TIGR00606 266 KLDneiKALKSRKKQMEKDNSELELK-MEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQREL------EKLNKERRLL 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 426 EIKQIEVYKSHSKfMKTKIDQLKQELSKKESELLALQTKLET-----------------------LSNQNSDCKQHIEVL 482
Cdd:TIGR00606 339 NQEKTELLVEQGR-LQLQADRHQEHIRARDSLIQSLATRLELdgfergpfserqiknfhtlvierQEDEAKTAAQLCADL 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 483 KESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGeirDMKDMLEVKERkinvLQKKIENLqeQ 562
Cdd:TIGR00606 418 QSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEG---SSDRILELDQE----LRKAEREL--S 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 563 LRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKeQRERDDRERLEEIESFRKENKDLKEKVNALQA 642
Cdd:TIGR00606 489 KAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRT-QMEMLTKDKMDKDEQIRKIKSRHSDELTSLLG 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 643 ELTEK---ESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLFN---------QMYNPAHN 710
Cdd:TIGR00606 568 YFPNKkqlEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDvcgsqdeesDLERLKEE 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 711 IEDDSRMNPEFADR-------LKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLtLRHMKDQNK 783
Cdd:TIGR00606 648 IEKSSKQRAMLAGAtavysqfITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESE-LKKKEKRRD 726
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 784 KVANLKYNQQLEKKKNAQLLEEVRRREDSMvdnsqHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAhlanlrIE 863
Cdd:TIGR00606 727 EMLGLAPGRQSIIDLKEKEIPELRNKLQKV-----NRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTI------ME 795
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568987518 864 RRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQE-EVMALKREKDRLVHQLKQQVGRPARQTQNRMK 937
Cdd:TIGR00606 796 RFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHElDTVVSKIELNRKLIQDQQEQIQHLKSKTNELK 870
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
724-885 |
1.72e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.15 E-value: 1.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 724 RLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESltlrHMKDQNKKVAnlKYNQQLEKKKNAQLL 803
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLEL----EIEEVEARIK--KYEEQLGNVRNNKEY 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 804 EEVRRREDSMVDNSQHL--QIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEmKQEALLA 881
Cdd:COG1579 92 EALQKEIESLKRRISDLedEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEA-EREELAA 170
|
....
gi 568987518 882 AISE 885
Cdd:COG1579 171 KIPP 174
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
149-561 |
1.73e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.82 E-value: 1.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 149 DLQAQLKELQRENDLLRKELDIKDSKLGssmnsiktfwspELKKERVLRKEEAARmsvLKEQMRVSHEENQLLDARRTKh 228
Cdd:TIGR02168 702 ELRKELEELEEELEQLRKELEELSRQIS------------ALRKDLARLEAEVEQ---LEERIAQLSKELTELEAEIEE- 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 229 LQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIeltEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNA 308
Cdd:TIGR02168 766 LEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL---REALDELRAELTLLNEEAANLRERLESLERRIAATERRLED 842
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 309 RDESIKKLLEMLQSKglpSKSLEDDNErtrRMAEAESQvshLEVILDQKEKENIHLREELHRRSQLqpepaktkalqtvi 388
Cdd:TIGR02168 843 LEEQIEELSEDIESL---AAEIEELEE---LIEELESE---LEALLNERASLEEALALLRSELEEL-------------- 899
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 389 emkDTKIASLERNIRDLEDEVQMLkangvlntedreeeikqievykshskfmKTKIDQLKQELSKKESEllaLQTKLETL 468
Cdd:TIGR02168 900 ---SEELRELESKRSELRRELEEL----------------------------REKLAQLELRLEGLEVR---IDNLQERL 945
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 469 SNQNSDCKQHIEVLKESLTAKEQRAailQTEVDALRLRL--------------EEKESFLNKKTKQLQDLTEEKGTLAGE 534
Cdd:TIGR02168 946 SEEYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIkelgpvnlaaieeyEELKERYDFLTAQKEDLTEAKETLEEA 1022
|
410 420
....*....|....*....|....*..
gi 568987518 535 IRDMKDmlEVKERKINVLQKKIENLQE 561
Cdd:TIGR02168 1023 IEEIDR--EARERFKDTFDQVNENFQR 1047
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
447-581 |
1.87e-04 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 44.96 E-value: 1.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 447 LKQELSKKESELLALQTKLETLSNQnsdckqhievlkesLTAKEQRAAILQTEVDALRLRLEEKES-------FLNKKTK 519
Cdd:PRK09039 44 LSREISGKDSALDRLNSQIAELADL--------------LSLERQGNQDLQDSVANLRASLSAAEAersrlqaLLAELAG 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 520 QLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQL------------RDKDKQL----------TNLKDRV 577
Cdd:PRK09039 110 AGAAAEGRAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLaaleaaldasekRDRESQAkiadlgrrlnVALAQRV 189
|
....
gi 568987518 578 KSLQ 581
Cdd:PRK09039 190 QELN 193
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
392-566 |
1.88e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.15 E-value: 1.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 392 DTKIASLERNIRDLEDEVQMLKAngvlNTEDREEEIKQIevykshskfmKTKIDQLKQELSKKESELLALQTKLETLSNQ 471
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELED----ELAALEARLEAA----------KTELEDLEKEIKRLELEIEEVEARIKKYEEQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 472 nsdckqhievLKESLTAKEQRAaiLQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINV 551
Cdd:COG1579 82 ----------LGNVRNNKEYEA--LQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDE 149
|
170
....*....|....*
gi 568987518 552 LQKKIENLQEQLRDK 566
Cdd:COG1579 150 ELAELEAELEELEAE 164
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
276-692 |
2.00e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.14 E-value: 2.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 276 AEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSK------SLEDDNERTRRMAEAESQVSH 349
Cdd:COG4717 81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQElealeaELAELPERLEELEERLEELRE 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 350 LEVILDQKEKENIHLREELhRRSQLQPEPAKTKALQTVIEmkdtKIASLERNIRDLEDEVQMLKANGvlntEDREEEIKQ 429
Cdd:COG4717 161 LEEELEELEAELAELQEEL-EELLEQLSLATEEELQDLAE----ELEELQQRLAELEEELEEAQEEL----EELEEELEQ 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 430 IEVYKSHSKfMKTKIDQLKQeLSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEE 509
Cdd:COG4717 232 LENELEAAA-LEERLKEARL-LLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQA 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 510 KESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRdkdkQLTNLKDRVKSLQTDSSNTDT 589
Cdd:COG4717 310 LPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ----LEELEQEIAALLAEAGVEDEE 385
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 590 ALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKD-LKEKVNALQAELTEKESSLIDLKEHASSLAS--AGL 666
Cdd:COG4717 386 ELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEeLEEELEELEEELEELEEELEELREELAELEAelEQL 465
|
410 420
....*....|....*....|....*.
gi 568987518 667 KRDSKLKSLEIAIEQKKEECNKLEAQ 692
Cdd:COG4717 466 EEDGELAELLQELEELKAELRELAEE 491
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
379-607 |
2.62e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.01 E-value: 2.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 379 AKTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKA-NGVLNTEDREEEIKQievykshskfmktKIDQLKQELSKKESE 457
Cdd:COG3206 168 LRREEARKALEFLEEQLPELRKELEEAEAALEEFRQkNGLVDLSEEAKLLLQ-------------QLSELESQLAEARAE 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 458 LLALQTKLETLSNQNSDCKQHIEVLKES--LTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEkgtLAGEI 535
Cdd:COG3206 235 LAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQ---LQQEA 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 536 RDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNT----DTALATLEEALSEKE------RII 605
Cdd:COG3206 312 QRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVArelyESLLQRLEEARLAEAltvgnvRVI 391
|
..
gi 568987518 606 ER 607
Cdd:COG3206 392 DP 393
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
389-634 |
2.66e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 44.92 E-value: 2.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 389 EMKDTKIASLERNIRDLEDEVQMLkanGVLNTEDREEEIKQIEVYKSHSKFMKTK--IDQLKQELSKKESELLALQT-KL 465
Cdd:PRK05771 5 RMKKVLIVTLKSYKDEVLEALHEL---GVVHIEDLKEELSNERLRKLRSLLTKLSeaLDKLRSYLPKLNPLREEKKKvSV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 466 ETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKqLQDLTEEKGT--LAGEI-RDMKDML 542
Cdd:PRK05771 82 KSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGNFDLD-LSLLLGFKYVsvFVGTVpEDKLEEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 543 EVKERKINVLQKKIE---------NLQEQLRDKDKQLtnLKDRVKSLQTDSSNT-DTALATLEEALSEKERIIERLKeqr 612
Cdd:PRK05771 161 KLESDVENVEYISTDkgyvyvvvvVLKELSDEVEEEL--KKLGFERLELEEEGTpSELIREIKEELEEIEKERESLL--- 235
|
250 260
....*....|....*....|..
gi 568987518 613 erddrerlEEIESFRKENKDLK 634
Cdd:PRK05771 236 --------EELKELAKKYLEEL 249
|
|
| RecN |
COG0497 |
DNA repair ATPase RecN [Replication, recombination and repair]; |
476-700 |
2.66e-04 |
|
DNA repair ATPase RecN [Replication, recombination and repair];
Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 44.68 E-value: 2.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 476 KQHIEVLKESLTAKEQRAAILQ---TEVDALRLRLEEKESfLNKKTKQLQDLTEekgtLAGEIRDMKDMLEVKERKINVL 552
Cdd:COG0497 171 KKELEELRADEAERARELDLLRfqlEELEAAALQPGEEEE-LEEERRRLSNAEK----LREALQEALEALSGGEGGALDL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 553 QKKIENLQEQLRDKDKQLTNLKDRVKSlqtdssntdtALATLEEALSEKERIIERLkeqreRDDRERLEEIESFRKENKD 632
Cdd:COG0497 246 LGQALRALERLAEYDPSLAELAERLES----------ALIELEEAASELRRYLDSL-----EFDPERLEEVEERLALLRR 310
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568987518 633 LKEKvnaLQAELTEkessLIDLKEHASslasaglKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQL 700
Cdd:COG0497 311 LARK---YGVTVEE----LLAYAEELR-------AELAELENSDERLEELEAELAEAEAELLEAAEKL 364
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
723-915 |
3.65e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.05 E-value: 3.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 723 DRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELEsltlRHMKDQNKKVANLkyNQQLEKKK---- 798
Cdd:COG3883 16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQ----AEIDKLQAEIAEA--EAEIEERReelg 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 799 ------------------------------NAQLLEEVRRREDSMVDnsqhlQIEELMNALEKTRQELDATKARLASTQQ 848
Cdd:COG3883 90 eraralyrsggsvsyldvllgsesfsdfldRLSALSKIADADADLLE-----ELKADKAELEAKKAELEAKLAELEALKA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568987518 849 SLAEKEAHLANLRIERRKQLEEiLEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD 915
Cdd:COG3883 165 ELEAAKAELEAQQAEQEALLAQ-LSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
445-705 |
3.88e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 44.12 E-value: 3.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 445 DQLKQELSKKESELLALQTKLETL----SNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 520
Cdd:COG4372 2 DRLGEKVGKARLSLFGLRPKTGILiaalSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 521 LQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSE 600
Cdd:COG4372 82 LEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLES 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 601 KERIIERLKEQRERDDRERL-EEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAI 679
Cdd:COG4372 162 LQEELAALEQELQALSEAEAeQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDA 241
|
250 260
....*....|....*....|....*.
gi 568987518 680 EQKKEECNKLEAQLKKQAEQLFNQMY 705
Cdd:COG4372 242 LELEEDKEELLEEVILKEIEELELAI 267
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
339-586 |
4.10e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 44.23 E-value: 4.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 339 RMAEAESQVSHLEVILDQKEkENIHLREELHRRSQlqpepAKTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKANGVL 418
Cdd:PHA02562 175 KIRELNQQIQTLDMKIDHIQ-QQIKTYNKNIEEQR-----KKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVM 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 419 NTEDREEEIKQIEVYKSHskfMKTKIDQLKQELskkesellalqtKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQT 498
Cdd:PHA02562 249 DIEDPSAALNKLNTAAAK---IKSKIEQFQKVI------------KMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQH 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 499 EVDALRLRLEEkesfLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVK 578
Cdd:PHA02562 314 SLEKLDTAIDE----LEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELD 389
|
....*...
gi 568987518 579 SLQTDSSN 586
Cdd:PHA02562 390 KIVKTKSE 397
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
387-640 |
4.47e-04 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 44.51 E-value: 4.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 387 VIEMKDTKIASLERNIRDLEDEVQMLKaNGVLNTEDREEEI--KQIEVYKSHSKFMKTKIDQLKqELSKKESELLALQTK 464
Cdd:PRK01156 470 IINHYNEKKSRLEEKIREIEIEVKDID-EKIVDLKKRKEYLesEEINKSINEYNKIESARADLE-DIKIKINELKDKHDK 547
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 465 LETLSNQNSDCkqHIEVLKESLTA-KEQRAAILQTEVDALRLRLEEKesflnkkTKQLQDLTEEKGTLAGEIRDMK---- 539
Cdd:PRK01156 548 YEEIKNRYKSL--KLEDLDSKRTSwLNALAVISLIDIETNRSRSNEI-------KKQLNDLESRLQEIEIGFPDDKsyid 618
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 540 -----------------DMLEVKERKINVLQKKIENLQEQLRDKD---KQLTNLKDRVKSLQTDSSNTDTALATLEEALS 599
Cdd:PRK01156 619 ksireieneannlnnkyNEIQENKILIEKLRGKIDNYKKQIAEIDsiiPDLKEITSRINDIEDNLKKSRKALDDAKANRA 698
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 568987518 600 EKERIIERLK------EQRERDDRERLEEIESFRKENKDLKEKVNAL 640
Cdd:PRK01156 699 RLESTIEILRtrinelSDRINDINETLESMKKIKKAIGDLKRLREAF 745
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
264-411 |
5.04e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.00 E-value: 5.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 264 IELTEENFRrLQAEHDRQAKELfllRKTLEEMELRIETQKQTLNARDESIKKllemlqskglpsksleddneRTRRMAEA 343
Cdd:PRK12704 60 LEAKEEIHK-LRNEFEKELRER---RNELQKLEKRLLQKEENLDRKLELLEK--------------------REEELEKK 115
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568987518 344 ESQVSHLEVILDQKEKE--NIH--LREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLernIRDLEDEVQM 411
Cdd:PRK12704 116 EKELEQKQQELEKKEEEleELIeeQLQELERISGLTAEEAKEILLEKVEEEARHEAAVL---IKEIEEEAKE 184
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
473-703 |
5.43e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 44.13 E-value: 5.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 473 SDCKQHIEVLKESLTAKEQRAAILQTevdalrlrLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMlevkerkinvl 552
Cdd:PRK11281 39 ADVQAQLDALNKQKLLEAEDKLVQQD--------LEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQA----------- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 553 QKKIENLQEQLRDKDKQlTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRE------RLEEIESF 626
Cdd:PRK11281 100 QAELEALKDDNDEETRE-TLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAAlyansqRLQQIRNL 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 627 RKENKDLKEKVNALQAELTEKESSLIDLK--------EHASSLASAG-LKRDskLKSLEIAIEQK-----KEECN-KLEA 691
Cdd:PRK11281 179 LKGGKVGGKALRPSQRVLLQAEQALLNAQndlqrkslEGNTQLQDLLqKQRD--YLTARIQRLEHqlqllQEAINsKRLT 256
|
250
....*....|..
gi 568987518 692 QLKKQAEQLFNQ 703
Cdd:PRK11281 257 LSEKTVQEAQSQ 268
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
440-605 |
5.45e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 43.92 E-value: 5.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 440 MKTKIDQLKQELSKKESELLALQTKLETLSnqnsdckqhievlKESLTAKEQRAAILQTEVDALRLRLEEKEsflnkktk 519
Cdd:COG0542 402 VRMEIDSKPEELDELERRLEQLEIEKEALK-------------KEQDEASFERLAELRDELAELEEELEALK-------- 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 520 qlQDLTEEKgTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDR--------------VKSLQTDSS 585
Cdd:COG0542 461 --ARWEAEK-ELIEEIQELKEELEQRYGKIPELEKELAELEEELAELAPLLREEVTEediaevvsrwtgipVGKLLEGER 537
|
170 180
....*....|....*....|
gi 568987518 586 NTdtaLATLEEALseKERII 605
Cdd:COG0542 538 EK---LLNLEEEL--HERVI 552
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
210-574 |
6.19e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.18 E-value: 6.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 210 QMRVSH--EENQLLDARRTKHLqltiqalqDELRTQRDLnhlLQQESGNRGAEHFTIELTEENFRRLQAEHDRQA----- 282
Cdd:PRK04863 767 QWRYSRfpEVPLFGRAAREKRI--------EQLRAEREE---LAERYATLSFDVQKLQRLHQAFSRFIGSHLAVAfeadp 835
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 283 -KELFLLRKTLEEME---LRIETQKQTLNARDESIKKLLEMLQsKGLPSKSLEDDNERTRRMAEAESQVSHLEV------ 352
Cdd:PRK04863 836 eAELRQLNRRRVELEralADHESQEQQQRSQLEQAKEGLSALN-RLLPRLNLLADETLADRVEEIREQLDEAEEakrfvq 914
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 353 ----ILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRDL--EDEVQMLKANGVLNtedreee 426
Cdd:PRK04863 915 qhgnALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAHFsyEDAAEMLAKNSDLN------- 987
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 427 ikqievykshskfmktkiDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLR 506
Cdd:PRK04863 988 ------------------EKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVP 1049
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568987518 507 LEEKESflnkktKQLQDLTEEKGTLAGEIRDMKDMLEVK----ERKINVLQKKIENLQEQLRDKDKQLTNLK 574
Cdd:PRK04863 1050 ADSGAE------ERARARRDELHARLSANRSRRNQLEKQltfcEAEMDNLTKKLRKLERDYHEMREQVVNAK 1115
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
398-627 |
6.29e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 43.73 E-value: 6.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 398 LERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQ 477
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 478 HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIE 557
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ 195
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568987518 558 NLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERL--KEQRERDDRERLEEIESFR 627
Cdd:pfam07888 196 ELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLnaSERKVEGLGEELSSMAAQR 267
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
421-926 |
6.58e-04 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 43.56 E-value: 6.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 421 EDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEV 500
Cdd:pfam05483 219 EDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKEL 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 501 DALRLRLEEK-------ESFLNKKTKQLQDLTEEKGTLAGEIRDMKdmlEVKERKINVLQKKIENLQEQLRDKDKQLTNL 573
Cdd:pfam05483 299 EDIKMSLQRSmstqkalEEDLQIATKTICQLTEEKEAQMEELNKAK---AAHSFVVTEFEATTCSLEELLRTEQQRLEKN 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 574 KDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRErDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID 653
Cdd:pfam05483 376 EDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILA-EDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHD 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 654 LKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQlfnqmynpahnieddsrmNPEFADRLKQLDKEAS 733
Cdd:pfam05483 455 LEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLE------------------NKELTQEASDMTLELK 516
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 734 YYRDECGKAQAEVDRLLeilKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANL-KYNQQLEKKKNAQLLEEVRRREDS 812
Cdd:pfam05483 517 KHQEDIINCKKQEERML---KQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLdKSEENARSIEYEVLKKEKQMKILE 593
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 813 MVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIE---RRKQLEEILEMKQEallaAISEKDAN 889
Cdd:pfam05483 594 NKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELElasAKQKFEEIIDNYQK----EIEDKKIS 669
|
490 500 510
....*....|....*....|....*....|....*...
gi 568987518 890 IALLELSASKKKKTQEEVMALKREKD-RLVHQLKQQVG 926
Cdd:pfam05483 670 EEKLLEEVEKAKAIADEAVKLQKEIDkRCQHKIAEMVA 707
|
|
| ClyA_Cry6Aa-like |
cd22656 |
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes ... |
424-600 |
6.91e-04 |
|
Bacillus thuringiensis crystal 6Aa (Cry6Aa) toxin, and similar proteins; This model includes pesticidal Cry6Aa toxin from Bacillus thuringiensis, one of the many parasporal crystal (Cry) toxins produced during the sporulation phase of growth. Many of these proteins are toxic to numerous insect species and have been effectively used as proteinaceous insecticides to directly kill insect pests; some have been used to control insect growth on transgenic agricultural plants. Cry6Aa exists as a protoxin, which is activated by cleavage using trypsin. Structure studies for Cry6Aa support a mechanism of action by pore formation, similar to cytolysin A (ClyA)-type alpha pore-forming toxins (alpha-PFTs) such as HblB, and bioassay and mutation studies show that Cry6Aa is an active pore-forming toxin. Cry6Aa shows atypical features compared to other members of alpha-PFTs, including internal repeat sequences and small loop regions within major alpha helices.
Pssm-ID: 439154 [Multi-domain] Cd Length: 309 Bit Score: 43.13 E-value: 6.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 424 EEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSD--CKQHIEVLKESLtaKEQRAAILQtevd 501
Cdd:cd22656 124 DDLLKEAKKYQDKAAKVVDKLTDFENQTEKDQTALETLEKALKDLLTDEGGaiARKEIKDLQKEL--EKLNEEYAA---- 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 502 ALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKkienLQEQLRDKDKQLTNLKDRVKSLQ 581
Cdd:cd22656 198 KLKAKIDELKALIADDEAKLAAALRLIADLTAADTDLDNLLALIGPAIPALEK----LQGAWQAIATDLDSLKDLLEDDI 273
|
170
....*....|....*....
gi 568987518 582 TDSSNTDTALATLEEALSE 600
Cdd:cd22656 274 SKIPAAILAKLELEKAIEK 292
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
449-851 |
7.33e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.79 E-value: 7.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 449 QELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQ---RAAILqtEVDALRLRLEEKESFLNKKTKQLQDLT 525
Cdd:PRK04863 837 AELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRllpRLNLL--ADETLADRVEEIREQLDEAEEAKRFVQ 914
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 526 EEKGTLAgEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQ----TDSSNTDTALATLEEALSEK 601
Cdd:PRK04863 915 QHGNALA-QLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQRRAhfsyEDAAEMLAKNSDLNEKLRQR 993
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 602 eriIERLKEQRERDdRERLEEIES-FRKENK---DLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKlkSLEI 677
Cdd:PRK04863 994 ---LEQAEQERTRA-REQLRQAQAqLAQYNQvlaSLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARARRD--ELHA 1067
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 678 AIEQKKEECNKLEAQLKKQAEQLFNQmynpahnieddsrmnpefADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVE 757
Cdd:PRK04863 1068 RLSANRSRRNQLEKQLTFCEAEMDNL------------------TKKLRKLERDYHEMREQVVNAKAGWCAVLRLVKDNG 1129
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 758 NEKNDKDKKIAELESLTLRHMKDqnKKVANLKYNQQlekkKNAQLLEEVRRREDS---------MVDNSQHLQ------- 821
Cdd:PRK04863 1130 VERRLHRRELAYLSADELRSMSD--KALGALRLAVA----DNEHLRDVLRLSEDPkrperkvqfYIAVYQHLRerirqdi 1203
|
410 420 430
....*....|....*....|....*....|....*....
gi 568987518 822 ---------IEELMNALEKTRQELDATKARLASTQQSLA 851
Cdd:PRK04863 1204 irtddpveaIEQMEIELSRLTEELTSREQKLAISSESVA 1242
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
482-704 |
7.99e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.47 E-value: 7.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 482 LKESLTAKEQRAAILQTEVDALRLRLEEKEsflnkktKQLQDLTEEKGTLAGEirdmkdmlevkeRKINVLQKKIENLQE 561
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAE-------AALEEFRQKNGLVDLS------------EEAKLLLQQLSELES 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 562 QLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEAlsekeRIIERLKEQRERDDRERLEEIESFRKEN---KDLKEKVN 638
Cdd:COG3206 227 QLAEARAELAEAEARLAALRAQLGSGPDALPELLQS-----PVIQQLRAQLAELEAELAELSARYTPNHpdvIALRAQIA 301
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568987518 639 ALQAEL-TEKESSLIDLKEHASSLASaglkRDSKLKSLEIAIEQKKEECNKLEAQLK------KQAEQLFNQM 704
Cdd:COG3206 302 ALRAQLqQEAQRILASLEAELEALQA----REASLQAQLAQLEARLAELPELEAELRrlerevEVARELYESL 370
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
198-872 |
9.09e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.29 E-value: 9.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 198 KEEAARMSVLKEQMRVSH-----EENQLLDARRTKHLQLTIQALQDELRTQRD-LNHLLQQESGNRGAEHFTIELTEENF 271
Cdd:pfam12128 245 KLQQEFNTLESAELRLSHlhfgyKSDETLIASRQEERQETSAELNQLLRTLDDqWKEKRDELNGELSAADAAVAKDRSEL 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 272 RRLQAEHDRQAKELFLLRKTLEEMELRIETQkqtLNARDESIKKLLEMLQSkglpsksLEDDNERtRRMAEAESQVSHLE 351
Cdd:pfam12128 325 EALEDQHGAFLDADIETAAADQEQLPSWQSE---LENLEERLKALTGKHQD-------VTAKYNR-RRSKIKEQNNRDIA 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 352 VILDQKEKenihLREELHRrsQLQPEPAKTKALQTVIEmKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIK-QI 430
Cdd:pfam12128 394 GIKDKLAK----IREARDR--QLAVAEDDLQALESELR-EQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLlQL 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 431 EVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQ------------------- 491
Cdd:pfam12128 467 ENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELqlfpqagtllhflrkeapd 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 492 ----------RAAILQTEVD---------------ALRLRL------------EEKESFLNKKTKQLQDLTEEKGTLAGE 534
Cdd:pfam12128 547 weqsigkvisPELLHRTDLDpevwdgsvggelnlyGVKLDLkridvpewaaseEELRERLDKAEEALQSAREKQAAAEEQ 626
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 535 IRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRV-KSLQTDSSNTDTALATLEEALSEKERIIERLKEQRE 613
Cdd:pfam12128 627 LVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKnKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQK 706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 614 RDDRE-RLEEIESFRKENKDLKEKVNALQAELTEKESSL------IDlKEHASSLASAGL--KRDSKLKSLEIAIEQKKE 684
Cdd:pfam12128 707 EQKREaRTEKQAYWQVVEGALDAQLALLKAAIAARRSGAkaelkaLE-TWYKRDLASLGVdpDVIAKLKREIRTLERKIE 785
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 685 ECNKLEAQLkKQAEQLFNQMYNPAhnieddsrmNPEFADRLKQLDKEASYYRDECGKAQAEVDRLleiLKEVENEKNDKD 764
Cdd:pfam12128 786 RIAVRRQEV-LRYFDWYQETWLQR---------RPRLATQLSNIERAISELQQQLARLIADTKLR---RAKLEMERKASE 852
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 765 KKIAELESLtLRHMKDQNKKVANLKYNQ-----QLEKKKNAQLLEEVRRREDSMVDNSQHlQIEELMNAL-EKTRQELDA 838
Cdd:pfam12128 853 KQQVRLSEN-LRGLRCEMSKLATLKEDAnseqaQGSIGERLAQLEDLKLKRDYLSESVKK-YVEHFKNVIaDHSGSGLAE 930
|
730 740 750
....*....|....*....|....*....|....
gi 568987518 839 TKARLASTQQSLAEKEAHLANLRiERRKQLEEIL 872
Cdd:pfam12128 931 TWESLREEDHYQNDKGIRLLDYR-KLVPYLEQWF 963
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
443-946 |
9.24e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 43.29 E-value: 9.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 443 KIDQLKQELSKKESELLALQTkletlsnqnsdckqhievLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQ 522
Cdd:pfam12128 242 EFTKLQQEFNTLESAELRLSH------------------LHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKR 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 523 D-LTEEKGTLAGEIRDMKDMLEV-KERKINVLQKKIENLQEQLrdkdkqltnlkDRVKSLQTDSSNTDTALATLEEALSE 600
Cdd:pfam12128 304 DeLNGELSAADAAVAKDRSELEAlEDQHGAFLDADIETAAADQ-----------EQLPSWQSELENLEERLKALTGKHQD 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 601 KERIIERLKEQRERDDRERLEEIESFRKENKDLKEK--------VNALQAELTEK-ESSLIDLKEHASSLASAGLKRDSK 671
Cdd:pfam12128 373 VTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRqlavaeddLQALESELREQlEAGKLEFNEEEYRLKSRLGELKLR 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 672 LKSLEIA------IEQKKEECNKL-EAQLKKQAEQLFNQMYNPAHNIEDDsrmnpEFADRLKQLDKEASYYRDECGKAQA 744
Cdd:pfam12128 453 LNQATATpelllqLENFDERIERArEEQEAANAEVERLQSELRQARKRRD-----QASEALRQASRRLEERQSALDELEL 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 745 EVD----RLLEILKeveNEKNDKDKKIAELESLTLRHMKDQNKKVANLKYN------------QQLEKKKNAQLLEEVRR 808
Cdd:pfam12128 528 QLFpqagTLLHFLR---KEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGgelnlygvkldlKRIDVPEWAASEEELRE 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 809 REDSMVD--NSQHLQIEELMNALEKTRQELDATKA-----------------RLASTQQSLAEK-----EAHLAnLRIER 864
Cdd:pfam12128 605 RLDKAEEalQSAREKQAAAEEQLVQANGELEKASReetfartalknarldlrRLFDEKQSEKDKknkalAERKD-SANER 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 865 RKQLE---EILEMKQEALLAAISEKdaniaLLELSASKKKKTQEEVMALKREKDRLVHQL-KQQVGRPAR----QTQNRM 936
Cdd:pfam12128 684 LNSLEaqlKQLDKKHQAWLEEQKEQ-----KREARTEKQAYWQVVEGALDAQLALLKAAIaARRSGAKAElkalETWYKR 758
|
570
....*....|
gi 568987518 937 KLMADNYDED 946
Cdd:pfam12128 759 DLASLGVDPD 768
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
394-937 |
1.21e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.11 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 394 KIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKID---QLKQELSKKESELLALQtkletlSN 470
Cdd:TIGR00606 420 KERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDrilELDQELRKAERELSKAE------KN 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 471 QNSDCKqhievLKESLTAKEQRAAILQTevdalRLRLEEKESFLNKKT---KQLQDLTEEKGTLAGEIRDMKDMLEVKER 547
Cdd:TIGR00606 494 SLTETL-----KKEVKSLQNEKADLDRK-----LRKLDQEMEQLNHHTttrTQMEMLTKDKMDKDEQIRKIKSRHSDELT 563
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 548 KI-------NVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSE-KERIIERLKEQRERDDRER 619
Cdd:TIGR00606 564 SLlgyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSyEDKLFDVCGSQDEESDLER 643
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 620 L-EEIESFRKENKDLKEKVNALQA---ELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKK 695
Cdd:TIGR00606 644 LkEEIEKSSKQRAMLAGATAVYSQfitQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK 723
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 696 QAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDkdkkiaelesLTL 775
Cdd:TIGR00606 724 RRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTD----------VTI 793
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 776 RHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHL-QIEELMNALEKTRQELDATKARLASTQQSLAEKE 854
Cdd:TIGR00606 794 MERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELdTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEK 873
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 855 AHLANlRIERRKQLEEILEMKQEALLAAISE-KDANIALLELSASKKKKTQ--EEVMALKREKDRLVHQLKQQVGRPARQ 931
Cdd:TIGR00606 874 LQIGT-NLQRRQQFEEQLVELSTEVQSLIREiKDAKEQDSPLETFLEKDQQekEELISSKETSNKKAQDKVNDIKEKVKN 952
|
....*.
gi 568987518 932 TQNRMK 937
Cdd:TIGR00606 953 IHGYMK 958
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
622-855 |
1.24e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.51 E-value: 1.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 622 EIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLF 701
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 702 NQMYNP--------AHNIEDdsrmnpeFADRLKQLDKEASYYRDecgkaqaevdrlleILKEVENEKNDKDKKIAELESl 773
Cdd:COG3883 97 RSGGSVsyldvllgSESFSD-------FLDRLSALSKIADADAD--------------LLEELKADKAELEAKKAELEA- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 774 TLRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEK 853
Cdd:COG3883 155 KLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAA 234
|
..
gi 568987518 854 EA 855
Cdd:COG3883 235 AA 236
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
590-700 |
1.36e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.46 E-value: 1.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 590 ALATLEEALSEKERIIERLKEQRERDDRERLEEIEsfRKENKdLKEKVNALqaeltEKESSLIDLKEHASslasagLKRD 669
Cdd:PRK12704 51 AEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQ--KLEKR-LLQKEENL-----DRKLELLEKREEEL------EKKE 116
|
90 100 110
....*....|....*....|....*....|.
gi 568987518 670 SKLKSLEIAIEQKKEECNKLEAQLKKQAEQL 700
Cdd:PRK12704 117 KELEQKQQELEKKEEELEELIEEQLQELERI 147
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
150-622 |
1.47e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 42.62 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 150 LQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQLLDARRTKHL 229
Cdd:COG1196 321 LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 230 QLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEEN--FRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLN 307
Cdd:COG1196 401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEeaLEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 308 ARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQ----VSHLEVILDQKEKEN----------IHLREELHRRSQ 373
Cdd:COG1196 481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglaGAVAVLIGVEAAYEAaleaalaaalQNIVVEDDEVAA 560
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 374 LQPEPAKTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSK 453
Cdd:COG1196 561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 454 KESELLALQTKLETLSNQNSDCKQHIE-VLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLA 532
Cdd:COG1196 641 TLAGRLREVTLEGEGGSAGGSLTGGSRrELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 533 GEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKD-----------KQLTNLKDRVKSL--------------QTDSSNT 587
Cdd:COG1196 721 LEEEALEEQLEAEREELLEELLEEEELLEEEALEElpeppdleeleRELERLEREIEALgpvnllaieeyeelEERYDFL 800
|
490 500 510
....*....|....*....|....*....|....*
gi 568987518 588 DTALATLEEALSEKERIIERLKEQRerddRERLEE 622
Cdd:COG1196 801 SEQREDLEEARETLEEAIEEIDRET----RERFLE 831
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
221-629 |
1.81e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 42.27 E-value: 1.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 221 LDARRTKHLQLTIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIE 300
Cdd:pfam02463 613 LEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKE 692
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 301 TQKQTLNardesIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREEL-HRRSQLQPEPA 379
Cdd:pfam02463 693 EILRRQL-----EIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSrLKKEEKEEEKS 767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 380 KTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELL 459
Cdd:pfam02463 768 ELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK 847
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 460 ALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMK 539
Cdd:pfam02463 848 LEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEA 927
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 540 DMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTD----TALATLEEALSEKERIIERLKEQRERD 615
Cdd:pfam02463 928 EILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNlmaiEEFEEKEERYNKDELEKERLEEEKKKL 1007
|
410
....*....|....
gi 568987518 616 DRERLEEIESFRKE 629
Cdd:pfam02463 1008 IRAIIEETCQRLKE 1021
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
293-921 |
1.85e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 42.47 E-value: 1.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 293 EEMELRIETQKQTLnardesiKKLLEMLQSKglpsksLEDDNERTRRMAEAESQVShlEVILDQKEkeniHLREELHRRS 372
Cdd:pfam01576 60 EEMRARLAARKQEL-------EEILHELESR------LEEEEERSQQLQNEKKKMQ--QHIQDLEE----QLDEEEAARQ 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 373 QLQPEP----AKTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKAngvlNTEDREEEIKQIEVYKSHSKFMKTKIDQLK 448
Cdd:pfam01576 121 KLQLEKvtteAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTS----NLAEEEEKAKSLSKLKNKHEAMISDLEERL 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 449 QELSKKESELLALQTKLE----TLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVD---------------------AL 503
Cdd:pfam01576 197 KKEEKGRQELEKAKRKLEgestDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEeetaqknnalkkireleaqisEL 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 504 RLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEV-------KERKINVLQKKIEnlqEQLRDKDKQLTNLKDR 576
Cdd:pfam01576 277 QEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAqqelrskREQEVTELKKALE---EETRSHEAQLQEMRQK 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 577 vkslqtdssnTDTALATLEEALSEKERI---IERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLID 653
Cdd:pfam01576 354 ----------HTQALEELTEQLEQAKRNkanLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSE 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 654 LKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEaqlkKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEAS 733
Cdd:pfam01576 424 SERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLS----KDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERN 499
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 734 YYRDECgKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVAN--LKYNQQLEKKKNA-QLLEEVRRR- 809
Cdd:pfam01576 500 SLQEQL-EEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRelEALTQQLEEKAAAyDKLEKTKNRl 578
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 810 ----EDSMVDNSQHLQieeLMNALEKTRQELDatkarlastqQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISE 885
Cdd:pfam01576 579 qqelDDLLVDLDHQRQ---LVSNLEKKQKKFD----------QMLAEEKAISARYAEERDRAEAEAREKETRALSLARAL 645
|
650 660 670
....*....|....*....|....*....|....*...
gi 568987518 886 KDANIALLELSASKK--KKTQEEVMALKREKDRLVHQL 921
Cdd:pfam01576 646 EEALEAKEELERTNKqlRAEMEDLVSSKDDVGKNVHEL 683
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
588-694 |
2.31e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 41.99 E-value: 2.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 588 DTALA-------TLEEALSEKERIIERLKEQRER----DDRERLEEIESFRKENKDLKEKVNALQAELtEKESSLIdlkE 656
Cdd:COG0542 396 DEAAArvrmeidSKPEELDELERRLEQLEIEKEAlkkeQDEASFERLAELRDELAELEEELEALKARW-EAEKELI---E 471
|
90 100 110
....*....|....*....|....*....|....*...
gi 568987518 657 HASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLK 694
Cdd:COG0542 472 EIQELKEELEQRYGKIPELEKELAELEEELAELAPLLR 509
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
444-685 |
2.51e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.43 E-value: 2.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 444 IDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQD 523
Cdd:COG4372 26 IAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELES 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 524 LTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKEr 603
Cdd:COG4372 106 LQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQA- 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 604 IIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK 683
Cdd:COG4372 185 LDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELE 264
|
..
gi 568987518 684 EE 685
Cdd:COG4372 265 LA 266
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
595-695 |
2.52e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.77 E-value: 2.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 595 EEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGL-------- 666
Cdd:COG2433 387 EKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERreirkdre 466
|
90 100 110
....*....|....*....|....*....|.
gi 568987518 667 --KRDSKLKSLEIAIEQKKEECNKLEAQLKK 695
Cdd:COG2433 467 isRLDREIERLERELEEERERIEELKRKLER 497
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
504-871 |
2.95e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 41.48 E-value: 2.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 504 RLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQtD 583
Cdd:COG5185 162 KDIFGKLTQELNQNLKKLEIFGLTLGLLKGISELKKAEPSGTVNSIKESETGNLGSESTLLEKAKEIINIEEALKGFQ-D 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 584 SSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIEsfrKENKDLKEKVNALQAELTEKESSlIDLKEHASSLaS 663
Cdd:COG5185 241 PESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLN---ENANNLIKQFENTKEKIAEYTKS-IDIKKATESL-E 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 664 AGLKRDSKLKSLEIAIEQKKEECNKLEAQLKKQAEQLFNQMynpahNIEDDSRMNPEFADRLKQLDKEASYYRDEcgkAQ 743
Cdd:COG5185 316 EQLAAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENL-----EAIKEEIENIVGEVELSKSSEELDSFKDT---IE 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 744 AEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIE 823
Cdd:COG5185 388 STKESLDEIPQNQRGYAQEILATLEDTLKAADRQIEELQRQIEQATSSNEEVSKLLNELISELNKVMREADEESQSRLEE 467
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 568987518 824 ELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEI 871
Cdd:COG5185 468 AYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGV 515
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
760-924 |
3.50e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 41.23 E-value: 3.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 760 KNDKDKKIAELESLTLRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEElmnALEKTRQELDAT 839
Cdd:PRK12705 27 KRQRLAKEAERILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARREREELQREEERLVQKEE---QLDARAEKLDNL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 840 KARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKDRLVH 919
Cdd:PRK12705 104 ENQLEEREKALSARELELEELEKQLDNELYRVAGLTPEQARKLLLKLLDAELEEEKAQRVKKIEEEADLEAERKAQNILA 183
|
....*
gi 568987518 920 QLKQQ 924
Cdd:PRK12705 184 QAMQR 188
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
380-602 |
4.13e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.58 E-value: 4.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 380 KTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKANgvlnTEDREEEIKQIEvykshskfmkTKIDQLKQELSKKESELL 459
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEE----YNELQAELEALQ----------AEIDKLQAEIAEAEAEIE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 460 ALQTKLETL---SNQNSDCKQHIEVLKESLTAKE--QRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE 534
Cdd:COG3883 83 ERREELGERaraLYRSGGSVSYLDVLLGSESFSDflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEAL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568987518 535 IRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKE 602
Cdd:COG3883 163 KAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| Lebercilin |
pfam15619 |
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of ... |
443-603 |
4.32e-03 |
|
Ciliary protein causing Leber congenital amaurosis disease; Lebercilin is a family of eukaryotic ciliary proteins. Mutations in the gene, LCA5, are implicated in the disease Leber congenital amaurosis. In photoreceptors, lebercilin is uniquely localized at the cilium that bridges the inner and outer segments. Lebercilin functions as an integral element of selective protein transport through photoreceptor cilia. Lebercilin specifically interacts with the intraflagellar transport (IFT), and disruption of IFT can lead to Leber congenital amaurosis.
Pssm-ID: 464776 [Multi-domain] Cd Length: 193 Bit Score: 39.50 E-value: 4.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 443 KIDQLKQELSKKESELLALQTKLETL--------------SNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLE 508
Cdd:pfam15619 12 KIKELQNELAELQSKLEELRKENRLLkrlqkrqekalgkyEGTESELPQLIARHNEEVRVLRERLRRLQEKERDLERKLK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 509 EKESFL---NKKTKQLQDLTEEKG-----TLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRdkdKQLTNLKDRVKSL 580
Cdd:pfam15619 92 EKEAELlrlRDQLKRLEKLSEDKNlaereELQKKLEQLEAKLEDKDEKIQDLERKLELENKSFR---RQLAAEKKKHKEA 168
|
170 180
....*....|....*....|...
gi 568987518 581 QTDSSNTDTALATLEEALSEKER 603
Cdd:pfam15619 169 QEEVKILQEEIERLQQKLKEKER 191
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
333-937 |
4.63e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 40.93 E-value: 4.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 333 DNERTRRmaEAESQVSHLEVILDQKEKENIHLREELHRrsqlqpepaktkaLQTVIEMKDTKIASLERNIRDLEDEVQML 412
Cdd:pfam01576 402 DSEHKRK--KLEGQLQELQARLSESERQRAELAEKLSK-------------LQSELESVSSLLNEAEGKNIKLSKDVSSL 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 413 KANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQR 492
Cdd:pfam01576 467 ESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEG 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 493 AAILQTEVDALRLRLEEKESFLNKKTKQlqdlteeKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTN 572
Cdd:pfam01576 547 KKRLQRELEALTQQLEEKAAAYDKLEKT-------KNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISAR 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 573 LKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQReRDDRERLEEIESFR----KENKDLKEKVNALQAELTEKE 648
Cdd:pfam01576 620 YAEERDRAEAEAREKETRALSLARALEEALEAKEELERTN-KQLRAEMEDLVSSKddvgKNVHELERSKRALEQQVEEMK 698
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 649 SSLIDLKEHASSLASAGLKRDSKLKSLEIAI--------EQKKEECNKLEAQLKKQAEQLFNQMYNPAHNIEDDSRMNPE 720
Cdd:pfam01576 699 TQLEELEDELQATEDAKLRLEVNMQALKAQFerdlqardEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELD 778
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 721 FADRLKQLDkEASYYRDECGKA-----------QAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKD-----QNKK 784
Cdd:pfam01576 779 LKELEAQID-AANKGREEAVKQlkklqaqmkdlQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDlaaseRARR 857
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 785 VANLKYNQQLEK-----KKNAQLLEEVRRREDSMVDNSQHLQIE----ELMN-ALEKTRQELDATKARLASTQQSLAEKE 854
Cdd:pfam01576 858 QAQQERDELADEiasgaSGKSALQDEKRRLEARIAQLEEELEEEqsntELLNdRLRKSTLQVEQLTTELAAERSTSQKSE 937
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 855 ahlaNLRIERRKQLEEILEMKQEALLAAISEKDANIALLElsaSKKKKTQEEVMALKREkdrlvhqlKQQVGRPARQTQN 934
Cdd:pfam01576 938 ----SARQQLERQNKELKAKLQEMEGTVKSKFKSSIAALE---AKIAQLEEQLEQESRE--------RQAANKLVRRTEK 1002
|
...
gi 568987518 935 RMK 937
Cdd:pfam01576 1003 KLK 1005
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
503-643 |
5.19e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 40.00 E-value: 5.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 503 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDmlevkerkinVLQKKIENLQEQLRDKDK----QLTNLKDRVK 578
Cdd:smart00787 145 LKEGLDENLEGLKEDYKLLMKELELLNSIKPKLRDRKD----------ALEEELRQLKQLEDELEDcdptELDRAKEKLK 214
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568987518 579 SLQTDSSNTDTALATLEEALSEKERIIERLKEQRErDDRERLEEIESFRKENKD--------LKEKVNALQAE 643
Cdd:smart00787 215 KLLQEIMIKVKKLEELEEELQELESKIEDLTNKKS-ELNTEIAEAEKKLEQCRGftfkeiekLKEQLKLLQSL 286
|
|
| XRN1 |
COG5049 |
5'-3' exonuclease [Replication, recombination and repair]; |
246-448 |
5.27e-03 |
|
5'-3' exonuclease [Replication, recombination and repair];
Pssm-ID: 227382 [Multi-domain] Cd Length: 953 Bit Score: 40.68 E-value: 5.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 246 LNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGL 325
Cdd:COG5049 366 LAILGSFEDDIFKKDHIQEERKNESLERFSLRKERKEGLKGMPRVVYEQKKLIGSIKPTLMDQLQEKKSPDLPDEEFIDT 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 326 PSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASlernirDL 405
Cdd:COG5049 446 LALPKDLDMKNHELFLKRFANDLGLSISKAIKSKGNYSLEMDIASDSPDEDEEEFESEVDSIRKIPDKYVNI------IV 519
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 568987518 406 EDEVQmlkaNGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLK 448
Cdd:COG5049 520 EEEEE----NETEKTVNLRFPGWKERYYTSKLHFTTDSEEKIR 558
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
428-555 |
5.29e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 40.18 E-value: 5.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 428 KQIEVYKSHSKFMKTKIDQLKQELSKKESE----------LLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQ 497
Cdd:pfam15905 184 GKLQVTQKNLEHSKGKVAQLEEKLVSTEKEkieeksetekLLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEIESLK 263
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568987518 498 TEVDALRLRLEEKESFLNKKTKQLQDLTEEK--------GTLAGEIRDMKDMLEVKERKINVLQKK 555
Cdd:pfam15905 264 QSLEEKEQELSKQIKDLNEKCKLLESEKEELlreyeekeQTLNAELEELKEKLTLEEQEHQKLQQK 329
|
|
| CagA_N |
pfam18971 |
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ... |
503-807 |
6.04e-03 |
|
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.
Pssm-ID: 408741 [Multi-domain] Cd Length: 876 Bit Score: 40.53 E-value: 6.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 503 LRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDM-KDMLEVKER-KINVLQKKIENLQEQLRDKDkqltNLKDRV-KS 579
Cdd:pfam18971 561 LENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFnKAVAEAKSTgNYDEVKKAQKDLEKSLRKRE----HLEKEVeKK 636
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 580 LQTDSSNTDTALATlEEALSEKERIIERLKEQRERDDRErLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHAS 659
Cdd:pfam18971 637 LESKSGNKNKMEAK-AQANSQKDEIFALINKEANRDARA-IAYTQNLKGIKRELSDKLEKISKDLKDFSKSFDEFKNGKN 714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 660 SLASaglKRDSKLKSLEIAIE---------QKKEECNKLEAQLKKQAEQLFNQMYNPAHNIED---DSRMNPEFADRLKQ 727
Cdd:pfam18971 715 KDFS---KAEETLKALKGSVKdlginpewiSKVENLNAALNEFKNGKNKDFSKVTQAKSDLENsvkDVIINQKVTDKVDN 791
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 728 LDKEASyyrdeCGKAQAEVDRLLEILkevenekndkdkkiAELESLTLRHMKDQNKKvanlkyNQQLEKKKNAQLLEEVR 807
Cdd:pfam18971 792 LNQAVS-----VAKAMGDFSRVEQVL--------------ADLKNFSKEQLAQQAQK------NEDFNTGKNSELYQSVK 846
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
694-906 |
6.89e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 40.49 E-value: 6.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 694 KKQAEQLFNQMYNPAHNIEDDSRMNPEFADRLKQLDKEASYYRDECGKA---QAEVDRLLEILKEVENEKNDKDKKIAEL 770
Cdd:pfam17380 295 KMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAmerERELERIRQEERKRELERIRQEEIAMEI 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 771 ESLTLRHMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKAR-LASTQQS 849
Cdd:pfam17380 375 SRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAReMERVRLE 454
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568987518 850 LAEKEAHLANLRIERRKQLEEILEM-KQEALLAAISEKDANIALLELSASKKKKTQEE 906
Cdd:pfam17380 455 EQERQQQVERLRQQEEERKRKKLELeKEKRDRKRAEEQRRKILEKELEERKQAMIEEE 512
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
149-391 |
7.12e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 40.13 E-value: 7.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 149 DLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQLLD--ARRT 226
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAelEAQK 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 227 KHLQLTIQALQdELRTQRDLNHLLQQESGNRGAEHFTIelteenFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTL 306
Cdd:COG4942 104 EELAELLRALY-RLGRQPPLALLLSPEDFLDAVRRLQY------LKYLAPARREQAEELRADLAELAALRAELEAERAEL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 307 NARDESIKKLLEMLQSkglpsksleDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQT 386
Cdd:COG4942 177 EALLAELEEERAALEA---------LKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
|
....*
gi 568987518 387 VIEMK 391
Cdd:COG4942 248 FAALK 252
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
238-651 |
7.49e-03 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 40.05 E-value: 7.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 238 DELRTQRD----LNHLLQQESGNRGAEHFTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESI 313
Cdd:pfam19220 20 EDLRSLKAdfsqLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAAL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 314 KkllemlqskglpskSLEDDNERTR-RMAEAESQVSHLEVILDQKEKENIHLREELhrrsqlqpepaktKALQTVIEMKD 392
Cdd:pfam19220 100 R--------------EAEAAKEELRiELRDKTAQAEALERQLAAETEQNRALEEEN-------------KALREEAQAAE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 393 TKIASLERNIRDLEDEVQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSnqn 472
Cdd:pfam19220 153 KALQRAEGELATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEGQLAAEQAERERAE--- 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 473 sdckqhievlkeslTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVL 552
Cdd:pfam19220 230 --------------AQLEEAVEAHRAERASLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAERRLKEASIERDTL 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 553 QKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKD 632
Cdd:pfam19220 296 ERRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASLSDRIAELTKRFEVERAALEQANRR 375
|
410
....*....|....*....
gi 568987518 633 LKEKVNALQAELTEKESSL 651
Cdd:pfam19220 376 LKEELQRERAERALAQGAL 394
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
354-510 |
7.72e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.14 E-value: 7.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 354 LDQKEKENIHLREEL-HRRSQLQpepAKTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKANgVLNTEDREEEIKQIEV 432
Cdd:COG1579 15 LDSELDRLEHRLKELpAELAELE---DELAALEARLEAAKTELEDLEKEIKRLELEIEEVEAR-IKKYEEQLGNVRNNKE 90
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568987518 433 YKSHSKfmktKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEK 510
Cdd:COG1579 91 YEALQK----EIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
|
|
| DUF4618 |
pfam15397 |
Domain of unknown function (DUF4618); This family of proteins is found in eukaryotes. Proteins ... |
428-656 |
8.45e-03 |
|
Domain of unknown function (DUF4618); This family of proteins is found in eukaryotes. Proteins in this family are typically between 238 and 363 amino acids in length. There are two conserved sequence motifs: EYP and KCTPD.
Pssm-ID: 464704 [Multi-domain] Cd Length: 258 Bit Score: 39.17 E-value: 8.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 428 KQIEVYKSHSKFMKTKIDQLKQEL-------SKKESELLALQTKLETLsnqnsdckqhIEVLKESLtakeqraailQTEV 500
Cdd:pfam15397 6 TSLEELKKHEDFLTKLNLELIKAIqdtedstALKVRKLLQQYEKFGTI----------ISILEYSN----------KKQL 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 501 DALRLRLEEKESFLNKKTKQLQDLTEEkgtLAGEIRDMKDMLEV----KERKINVLQKKIENLQEQLRD-KDKQLTNLKD 575
Cdd:pfam15397 66 QQAKAELQEWEEKEESKLNKLEQQLEQ---LNAKIQKTQEELNFlstyKDKEYPVKAVQIANLVRQLQQlKDSQQDELDE 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 576 RVKSLQTDssntdtaLATLEEALSEKERII------------ERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAE 643
Cdd:pfam15397 143 LEEMRRMV-------LESLSRKIQKKKEKIlsslaektlspyQESLLQKTRDNQVMLKEIEQFREFIDELEEEIPKLKAE 215
|
250
....*....|...
gi 568987518 644 LTEKESSLIDLKE 656
Cdd:pfam15397 216 VQQLQAQRQEPRE 228
|
|
| MPS2 |
pfam17060 |
Monopolar spindle protein 2; Is a fungal transmembrane protein which is part of the component ... |
480-615 |
8.84e-03 |
|
Monopolar spindle protein 2; Is a fungal transmembrane protein which is part of the component of the spindle pole body (SPB) required for the insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication. It seems that Mps2-Spc24 interaction may contribute to the localization of Spc24 and other kinetochore components to the inner plaque of the SPB.
Pssm-ID: 407228 [Multi-domain] Cd Length: 340 Bit Score: 39.57 E-value: 8.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 480 EVLKESLTAKEQRAAILQTEVDALRLRLEEKES------FLNKKTKQLQDLTEekgTLAGEIRDMKDMLEVKERKINVLQ 553
Cdd:pfam17060 105 ELKEDVKSSPRSEADSLGTPIKVDLLRNLKPQEspetprRINRKYKSLELRVE---SMKDELEFKDETIMEKDRELTELT 181
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568987518 554 KKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT----ALATLEEALSEKERIIERLKEQRERD 615
Cdd:pfam17060 182 STISKLKDKYDFLSREFEFYKQHHEHGGNNSIKTATkhefIISELKRKLQEQNRLIRILQEQIQFD 247
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
289-623 |
9.54e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 39.90 E-value: 9.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 289 RKTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQVSHLEVILDQKEKENIHLREEL 368
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALE 691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 369 HRRSQLQpepAKTKALQTVIEMKDTKIASLERNIRDLEDEVQMLKAN-----------GVLNTEDREEEIKQIEVYKSHS 437
Cdd:COG4913 692 EQLEELE---AELEELEEELDELKGEIGRLEKELEQAEEELDELQDRleaaedlarleLRALLEERFAAALGDAVERELR 768
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 438 KFMKTKIDQLKQELSKKESELLALQTKLetlsnqNSDCKQHIEVLKESLTAKEQRAAILqTEVDALRL-RLEEK-ESFLN 515
Cdd:COG4913 769 ENLEERIDALRARLNRAEEELERAMRAF------NREWPAETADLDADLESLPEYLALL-DRLEEDGLpEYEERfKELLN 841
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568987518 516 KKTKQlqDLTEEKGTLAGEIRDMKDMLEvkerKIN-VLQKKIENLQE--QLRDKDKQLTNLKDRVKSLQTDSSNTDTAla 592
Cdd:COG4913 842 ENSIE--FVADLLSKLRRAIREIKERID----PLNdSLKRIPFGPGRylRLEARPRPDPEVREFRQELRAVTSGASLF-- 913
|
330 340 350
....*....|....*....|....*....|....*.
gi 568987518 593 tlEEALSEK-----ERIIERLKEQRERDDRERLEEI 623
Cdd:COG4913 914 --DEELSEArfaalKRLIERLRSEEEESDRRWRARV 947
|
|
| |
