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Conserved domains on  [gi|568942903|ref|XP_006506685|]
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probable serine carboxypeptidase CPVL isoform X5 [Mus musculus]

Protein Classification

S10 family peptidase( domain architecture ID 304)

S10 family peptidase is a serine carboxypeptidase involved in the degradation of small peptides

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
Peptidase_S10 super family cl47550
Serine carboxypeptidase;
1-319 5.27e-88

Serine carboxypeptidase;


The actual alignment was detected with superfamily member pfam00450:

Pssm-ID: 459815 [Multi-domain]  Cd Length: 404  Bit Score: 269.49  E-value: 5.27e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903    1 MLYIDNPVGTGFSFTDHFQGYATSEDDVAQDLYSALIQFFTLFPEYAKNDFYVTGESYAGKYVPALAHYIHSLNPVR-KF 79
Cdd:pfam00450  86 ILFLDQPVGVGFSYSNTSSDYKTNDDKTAKDNYEFLQKFFEKFPEYKSRDFYIAGESYAGHYVPALAQEILDGNKNGsKP 165
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903   80 KIRLKGIAIGDAYTDPESIIGGYAAFLYEIGLLDEQQQKYFQKQCSKCVKYIkEQEWMKAFEILDKLLDGDVTtgssffq 159
Cdd:pfam00450 166 KINLKGLAIGNGLTDPLIQVNSYVPYAYYHGLISDELYESLKRQCCGKYDSC-DQLNTKCANLVENASKCIVS------- 237
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903  160 nvTGCTNYYNILQ-CT-------EPKEQSYFAKFLTLPQVRQAIHVgnqNFSDGA------EVEKHLREDTVKSVKPWLS 225
Cdd:pfam00450 238 --FGGINPYNIYTpCStdtcggyDPYDTSYAEKYLNRPEVRKALHV---NDSVGKweecndDVFNWLYDDIMKSMIPIVP 312
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903  226 EIMNY-YKVLIYNGQLDIIVAAALTERSLMAMDWKGSRAYRRarrkvWKIFKSDNEVAGYVRRVGKFHQVIVRGGGHILP 304
Cdd:pfam00450 313 NLLEGgLRVLIYSGDVDLICNYLGTEAWIKALNWSGKDDFRP-----WMVSPVDGQVAGYVKTYGNLTFATVKGAGHMVP 387
                         330
                  ....*....|....*
gi 568942903  305 YDQPMRSFDMINRFI 319
Cdd:pfam00450 388 EDQPEEALQMFQRFI 402
 
Name Accession Description Interval E-value
Peptidase_S10 pfam00450
Serine carboxypeptidase;
1-319 5.27e-88

Serine carboxypeptidase;


Pssm-ID: 459815 [Multi-domain]  Cd Length: 404  Bit Score: 269.49  E-value: 5.27e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903    1 MLYIDNPVGTGFSFTDHFQGYATSEDDVAQDLYSALIQFFTLFPEYAKNDFYVTGESYAGKYVPALAHYIHSLNPVR-KF 79
Cdd:pfam00450  86 ILFLDQPVGVGFSYSNTSSDYKTNDDKTAKDNYEFLQKFFEKFPEYKSRDFYIAGESYAGHYVPALAQEILDGNKNGsKP 165
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903   80 KIRLKGIAIGDAYTDPESIIGGYAAFLYEIGLLDEQQQKYFQKQCSKCVKYIkEQEWMKAFEILDKLLDGDVTtgssffq 159
Cdd:pfam00450 166 KINLKGLAIGNGLTDPLIQVNSYVPYAYYHGLISDELYESLKRQCCGKYDSC-DQLNTKCANLVENASKCIVS------- 237
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903  160 nvTGCTNYYNILQ-CT-------EPKEQSYFAKFLTLPQVRQAIHVgnqNFSDGA------EVEKHLREDTVKSVKPWLS 225
Cdd:pfam00450 238 --FGGINPYNIYTpCStdtcggyDPYDTSYAEKYLNRPEVRKALHV---NDSVGKweecndDVFNWLYDDIMKSMIPIVP 312
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903  226 EIMNY-YKVLIYNGQLDIIVAAALTERSLMAMDWKGSRAYRRarrkvWKIFKSDNEVAGYVRRVGKFHQVIVRGGGHILP 304
Cdd:pfam00450 313 NLLEGgLRVLIYSGDVDLICNYLGTEAWIKALNWSGKDDFRP-----WMVSPVDGQVAGYVKTYGNLTFATVKGAGHMVP 387
                         330
                  ....*....|....*
gi 568942903  305 YDQPMRSFDMINRFI 319
Cdd:pfam00450 388 EDQPEEALQMFQRFI 402
PTZ00472 PTZ00472
serine carboxypeptidase (CBP1); Provisional
1-322 6.06e-36

serine carboxypeptidase (CBP1); Provisional


Pssm-ID: 240429  Cd Length: 462  Bit Score: 134.95  E-value: 6.06e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903   1 MLYIDNPVGTGFSFTDHFQgYATSEDDVAQDLYSALIQFFTLFPEYAKNDFYVTGESYAGKYVPALAHYIHSLNPVRKFK 80
Cdd:PTZ00472 124 VIYVDQPAGVGFSYADKAD-YDHNESEVSEDMYNFLQAFFGSHEDLRANDLFVVGESYGGHYAPATAYRINMGNKKGDGL 202
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903  81 -IRLKGIAIGDAYTDPESIIGGYAAFLY-----EIG--LLDEQQQKYFQKQCSKCVKYIKE-QEWMKAFEILDKL---LD 148
Cdd:PTZ00472 203 yINLAGLAVGNGLTDPYTQYASYPRLAWdwckeKLGapCVSEEAYDEMSSMVPACQKKIKEcNSNPDDADSSCSVaraLC 282
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903 149 GDVTTGSSffqnVTGCTNYYNILQCTEP--KEQSYFAKFLTLPQVRQAIHVGNQNFSD-GAEVEKHLREDTVKSVKPWLS 225
Cdd:PTZ00472 283 NEYIAVYS----ATGLNNYDIRKPCIGPlcYNMDNTIAFMNREDVQSSLGVKPATWQScNMEVNLMFEMDWMKNFNYTVP 358
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903 226 EIM-NYYKVLIYNGQLDIIVAAALTERSLMAMDWKGSRAYRRARRKVWKifKSDNEVAGYVRRVGK-----FHQVIVRGG 299
Cdd:PTZ00472 359 GLLeDGVRVMIYAGDMDFICNWIGNKAWTLALQWPGNAEFNAAPDVPFS--AVDGRWAGLVRSAASntssgFSFVQVYNA 436
                        330       340
                 ....*....|....*....|...
gi 568942903 300 GHILPYDQPMRSFDMINRFIYDR 322
Cdd:PTZ00472 437 GHMVPMDQPAVALTMINRFLRNR 459
 
Name Accession Description Interval E-value
Peptidase_S10 pfam00450
Serine carboxypeptidase;
1-319 5.27e-88

Serine carboxypeptidase;


Pssm-ID: 459815 [Multi-domain]  Cd Length: 404  Bit Score: 269.49  E-value: 5.27e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903    1 MLYIDNPVGTGFSFTDHFQGYATSEDDVAQDLYSALIQFFTLFPEYAKNDFYVTGESYAGKYVPALAHYIHSLNPVR-KF 79
Cdd:pfam00450  86 ILFLDQPVGVGFSYSNTSSDYKTNDDKTAKDNYEFLQKFFEKFPEYKSRDFYIAGESYAGHYVPALAQEILDGNKNGsKP 165
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903   80 KIRLKGIAIGDAYTDPESIIGGYAAFLYEIGLLDEQQQKYFQKQCSKCVKYIkEQEWMKAFEILDKLLDGDVTtgssffq 159
Cdd:pfam00450 166 KINLKGLAIGNGLTDPLIQVNSYVPYAYYHGLISDELYESLKRQCCGKYDSC-DQLNTKCANLVENASKCIVS------- 237
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903  160 nvTGCTNYYNILQ-CT-------EPKEQSYFAKFLTLPQVRQAIHVgnqNFSDGA------EVEKHLREDTVKSVKPWLS 225
Cdd:pfam00450 238 --FGGINPYNIYTpCStdtcggyDPYDTSYAEKYLNRPEVRKALHV---NDSVGKweecndDVFNWLYDDIMKSMIPIVP 312
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903  226 EIMNY-YKVLIYNGQLDIIVAAALTERSLMAMDWKGSRAYRRarrkvWKIFKSDNEVAGYVRRVGKFHQVIVRGGGHILP 304
Cdd:pfam00450 313 NLLEGgLRVLIYSGDVDLICNYLGTEAWIKALNWSGKDDFRP-----WMVSPVDGQVAGYVKTYGNLTFATVKGAGHMVP 387
                         330
                  ....*....|....*
gi 568942903  305 YDQPMRSFDMINRFI 319
Cdd:pfam00450 388 EDQPEEALQMFQRFI 402
PTZ00472 PTZ00472
serine carboxypeptidase (CBP1); Provisional
1-322 6.06e-36

serine carboxypeptidase (CBP1); Provisional


Pssm-ID: 240429  Cd Length: 462  Bit Score: 134.95  E-value: 6.06e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903   1 MLYIDNPVGTGFSFTDHFQgYATSEDDVAQDLYSALIQFFTLFPEYAKNDFYVTGESYAGKYVPALAHYIHSLNPVRKFK 80
Cdd:PTZ00472 124 VIYVDQPAGVGFSYADKAD-YDHNESEVSEDMYNFLQAFFGSHEDLRANDLFVVGESYGGHYAPATAYRINMGNKKGDGL 202
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903  81 -IRLKGIAIGDAYTDPESIIGGYAAFLY-----EIG--LLDEQQQKYFQKQCSKCVKYIKE-QEWMKAFEILDKL---LD 148
Cdd:PTZ00472 203 yINLAGLAVGNGLTDPYTQYASYPRLAWdwckeKLGapCVSEEAYDEMSSMVPACQKKIKEcNSNPDDADSSCSVaraLC 282
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903 149 GDVTTGSSffqnVTGCTNYYNILQCTEP--KEQSYFAKFLTLPQVRQAIHVGNQNFSD-GAEVEKHLREDTVKSVKPWLS 225
Cdd:PTZ00472 283 NEYIAVYS----ATGLNNYDIRKPCIGPlcYNMDNTIAFMNREDVQSSLGVKPATWQScNMEVNLMFEMDWMKNFNYTVP 358
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903 226 EIM-NYYKVLIYNGQLDIIVAAALTERSLMAMDWKGSRAYRRARRKVWKifKSDNEVAGYVRRVGK-----FHQVIVRGG 299
Cdd:PTZ00472 359 GLLeDGVRVMIYAGDMDFICNWIGNKAWTLALQWPGNAEFNAAPDVPFS--AVDGRWAGLVRSAASntssgFSFVQVYNA 436
                        330       340
                 ....*....|....*....|...
gi 568942903 300 GHILPYDQPMRSFDMINRFIYDR 322
Cdd:PTZ00472 437 GHMVPMDQPAVALTMINRFLRNR 459
PLN02213 PLN02213
sinapoylglucose-malate O-sinapoyltransferase/ carboxypeptidase
1-319 4.27e-17

sinapoylglucose-malate O-sinapoyltransferase/ carboxypeptidase


Pssm-ID: 165857  Cd Length: 319  Bit Score: 80.54  E-value: 4.27e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903   1 MLYIDNPVGTGFSftdhfqgYATSEDDVAQDL------YSALIQFFTLFPEYAKNDFYVTGESYAGKYVPALAHYIHSLN 74
Cdd:PLN02213   4 IIFLDQPVGSGFS-------YSKTPIDKTGDIsevkrtHEFLQKWLSRHPQYFSNPLYVVGDSYSGMIVPALVQEISQGN 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903  75 PV-RKFKIRLKGIAIGDAYTDPESIIGGYAAFLYEIGLLDEQQQKYFQKQC-----------SKCVKYIKEQEWMKAFEI 142
Cdd:PLN02213  77 YIcCEPPINLQGYMLGNPVTYMDFEQNFRIPYAYGMGLISDEIYEPMKRICngnyynvdpsnTQCLKLTEEYHKCTAKIN 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903 143 LDKLL--DGDVTtgssffqNVTG--CTNY-YNILQCTEPKEqsyfakfltlpQVRQAIHVGNQNFSDGAEVEKHL--RED 215
Cdd:PLN02213 157 IHHILtpDCDVT-------NVTSpdCYYYpYHLIECWANDE-----------SVREALHIEKGSKGKWARCNRTIpyNHD 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903 216 TVKSVKPWLSEIMNYYKVLIYNGQLDIIVAAALTERSLMAMDWKGSRAYRRarrkvWKIfksDNEVAGYVRRVG-KFHQV 294
Cdd:PLN02213 219 IVSSIPYHMNNSISGYRSLIYSGDHDIAVPFLATQAWIRSLNYSPIHNWRP-----WMI---NNQIAGYTRAYSnKMTFA 290
                        330       340
                 ....*....|....*....|....*
gi 568942903 295 IVRGGGHILPYdQPMRSFDMINRFI 319
Cdd:PLN02213 291 TIKAGGHTAEY-RPNETFIMFQRWI 314
PLN02209 PLN02209
serine carboxypeptidase
1-319 1.02e-15

serine carboxypeptidase


Pssm-ID: 177859  Cd Length: 437  Bit Score: 77.37  E-value: 1.02e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903   1 MLYIDNPVGTGFSFTdHFQGYATSEDDVAQDLYSALIQFFTLFPEYAKNDFYVTGESYAGKYVPALAHYIHSLNPV-RKF 79
Cdd:PLN02209 120 IIFLDQPVGSGFSYS-KTPIERTSDTSEVKKIHEFLQKWLIKHPQFLSNPFYVVGDSYSGMIVPALVHEISKGNYIcCNP 198
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903  80 KIRLKGIAIGDAYTDPESIIGGYAAFLYEIGLLDEQQQKYFQKQC-----------SKCVKYIkeQEWMKAFEILDKLLD 148
Cdd:PLN02209 199 PINLQGYVLGNPITHIEFEQNFRIPYAHGMSLISDELYESLKRICkgnyfsvdpsnKKCLKLV--EEYHKCTDNINSHHT 276
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903 149 GDVTTGSSFFQNVT-GCTNY-YNILQCTEPKEqsyfakfltlpQVRQAIHVGNQNFSDGAEVEKHL--REDTVKSVKPWL 224
Cdd:PLN02209 277 LIANCDDSNTQHISpDCYYYpYHLVECWANNE-----------SVREALHVDKGSIGEWIRDHRGIpyKSDIRSSIPYHM 345
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903 225 SEIMNYYKVLIYNGQLDIIVAAALTERSLMAMDWKGSRAYRRarrkvWKIfksDNEVAGYVRRVG-KFHQVIVRGGGHIL 303
Cdd:PLN02209 346 NNSINGYRSLIFSGDHDITMPFQATQAWIKSLNYSIIDDWRP-----WMI---KGQIAGYTRTYSnKMTFATVKGGGHTA 417
                        330
                 ....*....|....*.
gi 568942903 304 PYdQPMRSFDMINRFI 319
Cdd:PLN02209 418 EY-LPEESSIMFQRWI 432
PLN03016 PLN03016
sinapoylglucose-malate O-sinapoyltransferase
1-319 1.46e-15

sinapoylglucose-malate O-sinapoyltransferase


Pssm-ID: 178590  Cd Length: 433  Bit Score: 77.00  E-value: 1.46e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903   1 MLYIDNPVGTGFSftdhfqgYATSEDDVAQDL------YSALIQFFTLFPEYAKNDFYVTGESYAGKYVPALAHYIHSLN 74
Cdd:PLN03016 118 IIFLDQPVGSGFS-------YSKTPIDKTGDIsevkrtHEFLQKWLSRHPQYFSNPLYVVGDSYSGMIVPALVQEISQGN 190
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903  75 PV-RKFKIRLKGIAIGDAYTDPESIIGGYAAFLYEIGLLDEQQQKYFQKQC-----------SKCVKYIKEQEWMKAFEI 142
Cdd:PLN03016 191 YIcCEPPINLQGYMLGNPVTYMDFEQNFRIPYAYGMGLISDEIYEPMKRICngnyynvdpsnTQCLKLTEEYHKCTAKIN 270
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903 143 LDKLL--DGDVTtgssffqNVTG--CTNY-YNILQCTEPKEqsyfakfltlpQVRQAIHVGNQNFSDGAEVEKHL--RED 215
Cdd:PLN03016 271 IHHILtpDCDVT-------NVTSpdCYYYpYHLIECWANDE-----------SVREALHIEKGSKGKWARCNRTIpyNHD 332
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568942903 216 TVKSVKPWLSEIMNYYKVLIYNGQLDIIVAAALTERSLMAMDWKGSRAYRRarrkvWKIfksDNEVAGYVRRVG-KFHQV 294
Cdd:PLN03016 333 IVSSIPYHMNNSISGYRSLIYSGDHDIAVPFLATQAWIRSLNYSPIHNWRP-----WMI---NNQIAGYTRAYSnKMTFA 404
                        330       340
                 ....*....|....*....|....*
gi 568942903 295 IVRGGGHILPYdQPMRSFDMINRFI 319
Cdd:PLN03016 405 TIKAGGHTAEY-RPNETFIMFQRWI 428
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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