|
Name |
Accession |
Description |
Interval |
E-value |
| CCDC144C |
pfam14915 |
CCDC144C protein coiled-coil region; This family includes the human protein CCDC144C and the ... |
891-1194 |
6.81e-153 |
|
CCDC144C protein coiled-coil region; This family includes the human protein CCDC144C and the ankyrin repeat domain-containing protein 26-like 1 found in eukaryotes. Its function remains unknown, however, it is known to contain a coiled-coil domain which corresponds to this region. The ankyrin repeat which features in this protein is a common amino acid motif.
Pssm-ID: 464371 [Multi-domain] Cd Length: 304 Bit Score: 469.47 E-value: 6.81e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 891 NQRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTGQLNSLKAENTMLSSKLD 970
Cdd:pfam14915 1 NCMLQDEIAMLRLEIDTIKNQNQEKEKKYLEDIEILKEKNDDLQKTLKLNEETLTKTVFQYNGQLNVLKAENTMLNSKLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 971 NEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERKL 1050
Cdd:pfam14915 81 NEKQNKERLETEVESYRSRLAAAIQDHEQSQTSKRDLELAFQRERDEWLRLQDKMNFDVSNLRDENEILSQQLSKAESKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1051 NSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDA 1130
Cdd:pfam14915 161 NSLENELHRTRDALREKTLLLESVQRDLSQAQCQKKELEHMYQNEQDKVNKYIGKQESLEERLAQLQSENMLLRQQLEDA 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568941650 1131 ANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAER 1194
Cdd:pfam14915 241 QNKADAKEKTVIDIQDQFQDIVKKLQAESEKQVLLLEERNKELINECNHLKERLYQYEKEKAER 304
|
|
| DUF3496 |
pfam12001 |
Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. ... |
1500-1607 |
1.37e-51 |
|
Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 110 amino acids in length.
Pssm-ID: 463425 [Multi-domain] Cd Length: 109 Bit Score: 177.16 E-value: 1.37e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1500 RSQMELRIKDLESQLYRMKA-QEDFDKIELEKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQNRSLLSTLS 1578
Cdd:pfam12001 1 RSQMELRIKDLESELSKMKTsQEDSNKIELEKYKQLYLEELKVRKSLSNKLNKTNERLAEVSTKLLVEKQQNRSLLSTLT 80
|
90 100
....*....|....*....|....*....
gi 568941650 1579 TRPVVECPCVGSFHNSLVFNRTLIPRENI 1607
Cdd:pfam12001 81 TRPVLESPCVGNLNNSLVLNRNFIPRENL 109
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
51-219 |
2.01e-40 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 152.03 E-value: 2.01e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 51 IHKAASVGDVAKVQHILILGKSgVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECA 130
Cdd:COG0666 91 LHAAARNGDLEIVKLLLEAGAD-VNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIV 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 131 AILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVD 210
Cdd:COG0666 170 KLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKD 249
|
....*....
gi 568941650 211 QLGSNRQMF 219
Cdd:COG0666 250 KDGLTALLL 258
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
42-213 |
7.74e-40 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 150.10 E-value: 7.74e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 42 HIHDKDMGKIHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKA 121
Cdd:COG0666 48 ALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLA 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 122 VQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVK 201
Cdd:COG0666 128 AYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLE 207
|
170
....*....|..
gi 568941650 202 KKASIHAVDQLG 213
Cdd:COG0666 208 AGADVNAKDNDG 219
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
51-215 |
1.04e-32 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 129.69 E-value: 1.04e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 51 IHKAASVGDVAKVQHILILGKSgVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECA 130
Cdd:COG0666 124 LHLAAYNGNLEIVKLLLEAGAD-VNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIV 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 131 AILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVD 210
Cdd:COG0666 203 KLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAAL 282
|
....*
gi 568941650 211 QLGSN 215
Cdd:COG0666 283 LDLLT 287
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
43-213 |
5.33e-30 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 121.60 E-value: 5.33e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 43 IHDKDMGKIHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAV 122
Cdd:COG0666 16 LLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 123 QCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKK 202
Cdd:COG0666 96 RNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEA 175
|
170
....*....|.
gi 568941650 203 KASIHAVDQLG 213
Cdd:COG0666 176 GADVNARDNDG 186
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
717-1564 |
1.04e-23 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 109.38 E-value: 1.04e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 717 ELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRK 796
Cdd:TIGR02168 221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 797 GEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQNarmlqdgilashLCKQKEIEMTQKKMTSE 876
Cdd:TIGR02168 301 EQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE------------ELESLEAELEELEAELE 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 877 VSVSHEKEKDLLHknQRLQDEVAVLRLEMDTIKSHNQEKEKRyledIKIANEKNDNLQRMVKLNEETFTKTIFQYT-GQL 955
Cdd:TIGR02168 369 ELESRLEELEEQL--ETLRSKVAQLELQIASLNNEIERLEAR----LERLEDRRERLQQEIEELLKKLEEAELKELqAEL 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 956 NSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMN--FDMSNLR 1033
Cdd:TIGR02168 443 EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKnqSGLSGIL 522
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1034 DnneVLSQQLSKTERKLNSLEIefhhtkdelrektlAL-KHAQRDLSQT-QCQMKEVEHMFQDEQGKVSKFMGKQesieE 1111
Cdd:TIGR02168 523 G---VLSELISVDEGYEAAIEA--------------ALgGRLQAVVVENlNAAKKAIAFLKQNELGRVTFLPLDS----I 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1112 RLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRF-------QAESQRHSLRLEDRnqeLVSECSHLRERL 1184
Cdd:TIGR02168 582 KGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvddldNALELAKKLRPGYR---IVTLDGDLVRPG 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1185 CQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKM 1264
Cdd:TIGR02168 659 GVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL 738
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1265 EDHLQKLELEKSKFEITIKKQSEEIDQLQENLsrvnlsEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVL 1344
Cdd:TIGR02168 739 EAEVEQLEERIAQLSKELTELEAEIEELEERL------EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL 812
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1345 KMTKKELNEYENRELNLRQDIknnhlemdipvSTLIKKIDDLTAKLETASskcLHLGKKNQLLQQELLLMRTIQKKCGKL 1424
Cdd:TIGR02168 813 TLLNEEAANLRERLESLERRI-----------AATERRLEDLEEQIEELS---EDIESLAAEIEELEELIEELESELEAL 878
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1425 EKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREvEERARQDLVEKLKQVNLFLQ-AQAASQESLEQLRENSNASVRSQM 1503
Cdd:TIGR02168 879 LNERASLEEALALLRSELEELSEELRELESKRSE-LRRELEELREKLAQLELRLEgLEVRIDNLQERLSEEYSLTLEEAE 957
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568941650 1504 ELRIKDLESQlyrMKAQEDFDKIElEKYKQL------YQEEFRARKSLSSKLNKTSEKLEEASSKLL 1564
Cdd:TIGR02168 958 ALENKIEDDE---EEARRRLKRLE-NKIKELgpvnlaAIEEYEELKERYDFLTAQKEDLTEAKETLE 1020
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
85-177 |
9.10e-21 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 88.25 E-value: 9.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 85 LHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHgADPNvMDSSGNTALHYAVYSENTSMAA 164
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVN-LKDNGRTALHYAARSGHLEIVK 78
|
90
....*....|...
gi 568941650 165 KLLAHNANIEAKN 177
Cdd:pfam12796 79 LLLEKGADINVKD 91
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
713-1371 |
9.34e-20 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 96.66 E-value: 9.34e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 713 KRLIELKRShCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSAD---QLSEKT 789
Cdd:TIGR02168 330 SKLDELAEE-LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNneiERLEAR 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 790 SEQLRRKGEQCQSEVEA--RQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQN----ARMLQDGILASHLCKQ 863
Cdd:TIGR02168 409 LERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREeleeAEQALDAAERELAQLQ 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 864 KEIEMTQKkMTSEVSVSHEKEKDLLHKNQRLQDEV------------------AVLRLEMDTIKSHNQEKEKRylediKI 925
Cdd:TIGR02168 489 ARLDSLER-LQENLEGFSEGVKALLKNQSGLSGILgvlselisvdegyeaaieAALGGRLQAVVVENLNAAKK-----AI 562
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 926 ANEKNDNLQRMVKLNEETFTKTIFQYTGqLNSLKAENTMLSSKLDNEKQnKERLETDVESFRSR------LASALHDHAE 999
Cdd:TIGR02168 563 AFLKQNELGRVTFLPLDSIKGTEIQGND-REILKNIEGFLGVAKDLVKF-DPKLRKALSYLLGGvlvvddLDNALELAKK 640
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1000 IQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEV--LSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRD 1077
Cdd:TIGR02168 641 LRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIeeLEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE 720
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1078 LSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQA 1157
Cdd:TIGR02168 721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA 800
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1158 ESQRHSlRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLK 1237
Cdd:TIGR02168 801 LREALD-ELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALL 879
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1238 KKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLE-------LEKSKFEITIKKQSEEIDQLQENLS-RVNLSEEDKEKL 1309
Cdd:TIGR02168 880 NERASLEEALALLRSELEELSEELRELESKRSELRreleelrEKLAQLELRLEGLEVRIDNLQERLSeEYSLTLEEAEAL 959
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568941650 1310 QKLTELKEslectvDQEQKRSSALEKELAEFKEVLKMTkkeLNEYEnrELNLRQDIKNNHLE 1371
Cdd:TIGR02168 960 ENKIEDDE------EEARRRLKRLENKIKELGPVNLAA---IEEYE--ELKERYDFLTAQKE 1010
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
51-184 |
2.98e-19 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 90.01 E-value: 2.98e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 51 IHKAASVGDVAKVQhILIlgKSG--VNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEE 128
Cdd:COG0666 157 LHLAAANGNLEIVK-LLL--EAGadVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLE 233
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 568941650 129 CAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPM 184
Cdd:COG0666 234 IVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLTLL 289
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
51-144 |
1.85e-18 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 81.70 E-value: 1.85e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 51 IHKAASVGDVAKVQHILILGkSGVNDRDKKDRTALHLACAYGHPEVVTLLVErKCEIDARDsESSTALIKAVQCQEEECA 130
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENG-ADANLQDKNGRTALHLAAKNGHLEIVKLLLE-HADVNLKD-NGRTALHYAARSGHLEIV 77
|
90
....*....|....
gi 568941650 131 AILLDHGADPNVMD 144
Cdd:pfam12796 78 KLLLEKGADINVKD 91
|
|
| ANKYR |
COG0666 |
Ankyrin repeat [Signal transduction mechanisms]; |
66-213 |
1.91e-17 |
|
Ankyrin repeat [Signal transduction mechanisms];
Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 85.01 E-value: 1.91e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 66 ILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDS 145
Cdd:COG0666 6 LLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDD 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568941650 146 SGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
Cdd:COG0666 86 GGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDG 153
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
700-1391 |
8.72e-17 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 87.03 E-value: 8.72e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 700 ASLLKIRDAVYSYKRLIELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKR 779
Cdd:TIGR02168 267 EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKL 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 780 RSADQLSEKTSEQLrrkgeqcQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSR---------EQNARM 850
Cdd:TIGR02168 347 EELKEELESLEAEL-------EELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERlearlerleDRRERL 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 851 LQDGILASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRL---QDEVAVLRLEMDTIKSHNQEKEKRY--LEDIKI 925
Cdd:TIGR02168 420 QQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALeelREELEEAEQALDAAERELAQLQARLdsLERLQE 499
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 926 ANEKNDNLQRMVKLNEETFTktifQYTGQLNSL--------KAENTMLSSKL-----DNEKQNKERLETDVESFRSR--- 989
Cdd:TIGR02168 500 NLEGFSEGVKALLKNQSGLS----GILGVLSELisvdegyeAAIEAALGGRLqavvvENLNAAKKAIAFLKQNELGRvtf 575
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 990 LASALHDHAEIQTAKRDL---EIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTE-RKLNSLEIEFHHTKDEL- 1064
Cdd:TIGR02168 576 LPLDSIKGTEIQGNDREIlknIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALElAKKLRPGYRIVTLDGDLv 655
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1065 -REKTLALKHAQRDLSqTQCQMKEVEHMfqdeQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVN 1143
Cdd:TIGR02168 656 rPGGVITGGSAKTNSS-ILERRREIEEL----EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA 730
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1144 IQDQFQDVLTRFQAESQRHSlRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLK-KQSMSEASLEVS 1222
Cdd:TIGR02168 731 LRKDLARLEAEVEQLEERIA-QLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEeLKALREALDELR 809
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1223 SRYRsNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQenlsrvNLS 1302
Cdd:TIGR02168 810 AELT-LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALL------NER 882
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1303 EEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNH-LEMDIPVsTLIK 1381
Cdd:TIGR02168 883 ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYsLTLEEAE-ALEN 961
|
730
....*....|
gi 568941650 1382 KIDDLTAKLE 1391
Cdd:TIGR02168 962 KIEDDEEEAR 971
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1061-1571 |
5.65e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.22 E-value: 5.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1061 KDELREKTLALKHAQRDLSQTQCQMKEVEHmfQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKT 1140
Cdd:COG1196 219 KEELKELEAELLLLKLRELEAELEELEAEL--EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1141 IVNIQDQFQDVLTRFQAESQRhSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLE 1220
Cdd:COG1196 297 LARLEQDIARLEERRRELEER-LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1221 VSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRvn 1300
Cdd:COG1196 376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE-- 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1301 LSEEDKEKLQKLTELKESLEctvdQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELN-LRQDIKNNHLEMDIPVSTL 1379
Cdd:COG1196 454 LEEEEEALLELLAELLEEAA----LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVL 529
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1380 IKKIDDLTAKLETASS---------------KCLHLGKKNQLLQQELLLMRTIQkkcgKLEKNKKQLEQEVVNLRSHMEK 1444
Cdd:COG1196 530 IGVEAAYEAALEAALAaalqnivveddevaaAAIEYLKAAKAGRATFLPLDKIR----ARAALAAALARGAIGAAVDLVA 605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1445 NMVEHSQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQMELRIKDLESQLYRMKAQEDFD 1524
Cdd:COG1196 606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 568941650 1525 KIELEKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQNR 1571
Cdd:COG1196 686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1033-1396 |
6.41e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 80.87 E-value: 6.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1033 RDNNEVLSQQLSKTERKLNSLEI------EFHHTKDELREKTLAL-----KHAQRDLSQTQCQMKEVEHMFQDEQGKVSK 1101
Cdd:TIGR02168 185 RENLDRLEDILNELERQLKSLERqaekaeRYKELKAELRELELALlvlrlEELREELEELQEELKEAEEELEELTAELQE 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1102 FMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQdvltrfqaesqrhslRLEDRNQELVSECSHLR 1181
Cdd:TIGR02168 265 LEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA---------------NLERQLEELEAQLEELE 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1182 ERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREavhha 1261
Cdd:TIGR02168 330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER----- 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1262 ekMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEklqkLTELKESLECTVDQEqkrsSALEKELAEFK 1341
Cdd:TIGR02168 405 --LEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEE----LEELQEELERLEEAL----EELREELEEAE 474
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 568941650 1342 EVLKMTKKELNEYENReLNLRQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSK 1396
Cdd:TIGR02168 475 QALDAAERELAQLQAR-LDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL 528
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
41-210 |
1.22e-14 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 78.53 E-value: 1.22e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 41 YHIHDKDMGKIHKAASVGDVAKVQHILILGkSGVNDRDKKDRTALHLACAYGHP---EVVTLLVERKCEIDARDSESSTA 117
Cdd:PHA03095 8 DIIMEAALYDYLLNASNVTVEEVRRLLAAG-ADVNFRGEYGKTPLHLYLHYSSEkvkDIVRLLLEAGADVNAPERCGFTP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 118 LIKAVQCQ-EEECAAILLDHGADPNVMDSSGNTALHyaVY----SENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENK 192
Cdd:PHA03095 87 LHLYLYNAtTLDVIKLLIKAGADVNAKDKVGRTPLH--VYlsgfNINPKVIRLLLRKGADVNALDLYGMTPLAVLLKSRN 164
|
170 180
....*....|....*....|
gi 568941650 193 QHI--VEFLVKKKASIHAVD 210
Cdd:PHA03095 165 ANVelLRLLIDAGADVYAVD 184
|
|
| PHA02875 |
PHA02875 |
ankyrin repeat protein; Provisional |
51-204 |
2.28e-14 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 77.34 E-value: 2.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 51 IHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECA 130
Cdd:PHA02875 72 LHDAVEEGDVKAVEELLDLGKFADDVFYKDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGI 151
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568941650 131 AILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKD-DLTPMLLAVKENKQHIVEFLVKKKA 204
Cdd:PHA02875 152 ELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNgCVAALCYAIENNKIDIVRLFIKRGA 226
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
745-1249 |
3.51e-14 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 78.29 E-value: 3.51e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 745 SETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTV 824
Cdd:pfam01576 57 AEAEEMRARLAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKL 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 825 KSHLNqVLEERNEtqrQLSREQNARMLQDGILASHLCKQKE--IEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLR 902
Cdd:pfam01576 137 EEDIL-LLEDQNS---KLSKERKLLEERISEFTSNLAEEEEkaKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRK 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 903 LEMDTIKSHNQEKE-KRYLEDIKIAN-EKNDNLQR-MVKLNEETFTKTIFQytGQLNSLKAENTMLSSKLDNEKQNKER- 978
Cdd:pfam01576 213 LEGESTDLQEQIAElQAQIAELRAQLaKKEEELQAaLARLEEETAQKNNAL--KKIRELEAQISELQEDLESERAARNKa 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 979 ------LETDVESFRSRLASALHDHAEIQT--AKRDLEIA-FQRARDEWFRVKDKMNFDMSNLRDNN-EVLSQQLSKTER 1048
Cdd:pfam01576 291 ekqrrdLGEELEALKTELEDTLDTTAAQQElrSKREQEVTeLKKALEEETRSHEAQLQEMRQKHTQAlEELTEQLEQAKR 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1049 KLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLD 1128
Cdd:pfam01576 371 NKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLN 450
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1129 DAANKAESKDKTIVNIQDQFQDVLTRFQAESqRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADT 1208
Cdd:pfam01576 451 EAEGKNIKLSKDVSSLESQLQDTQELLQEET-RQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDM 529
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 568941650 1209 LKKQSMSEASLEVssryrsnLEEEARDLKKKLGQLRSQLQE 1249
Cdd:pfam01576 530 KKKLEEDAGTLEA-------LEEGKKRLQRELEALTQQLEE 563
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
66-226 |
8.92e-14 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 75.83 E-value: 8.92e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 66 ILILGKSGVNDRDKKDRTALHLACAYGHP--EVVTLLVERKCEIDARDSESSTAL-IKAVQCQeeeCAAI----LLDHGA 138
Cdd:PHA03095 172 LLIDAGADVYAVDDRFRSLLHHHLQSFKPraRIVRELIRAGCDPAATDMLGNTPLhSMATGSS---CKRSlvlpLLIAGI 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 139 DPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAV----DQLGS 214
Cdd:PHA03095 249 SINARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGNTPLSLMVRNNNGRAVRAALAKNPSAETVaatlNTASV 328
|
170
....*....|..
gi 568941650 215 NRQMFEYDGKRL 226
Cdd:PHA03095 329 AGGDIPSDATRL 340
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
712-1339 |
2.14e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 75.74 E-value: 2.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 712 YKRL-IELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTS 790
Cdd:COG1196 215 YRELkEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 791 EQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQNARMLqdgilashlcKQKEIEMTQ 870
Cdd:COG1196 295 AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE----------AEAELAEAE 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 871 KKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEEtftktifq 950
Cdd:COG1196 365 EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE-------- 436
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 951 ytgqlnsLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEwfrvkdkmnfdmS 1030
Cdd:COG1196 437 -------EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL------------L 497
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1031 NLRDNNEVLSQQLSKTERKLNSLEIefHHTKDELREKTLALKHAQRDLSQTQCQMKEVEhmfQDEQGKvskfmgkqESIE 1110
Cdd:COG1196 498 EAEADYEGFLEGVKAALLLAGLRGL--AGAVAVLIGVEAAYEAALEAALAAALQNIVVE---DDEVAA--------AAIE 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1111 ERLAQLQSENTLLrqqlddAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENE 1190
Cdd:COG1196 565 YLKAAKAGRATFL------PLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRR 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1191 KAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQK 1270
Cdd:COG1196 639 AVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLE 718
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941650 1271 LELEKSKFEITIKKQSEEIDQLQEnlsrvnlsEEDKEKLQKLTELKESLEcTVDQEQKRSSALEKELAE 1339
Cdd:COG1196 719 EELEEEALEEQLEAEREELLEELL--------EEEELLEEEALEELPEPP-DLEELERELERLEREIEA 778
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1098-1465 |
3.46e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 75.10 E-value: 3.46e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1098 KVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKtivniqdqFQDVLTRFQaesqrhslrlEDRNQELVSEC 1177
Cdd:TIGR02169 171 KKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--------YQALLKEKR----------EYEGYELLKEK 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1178 SHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASL-EVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHRE 1256
Cdd:TIGR02169 233 EALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLeELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAE 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1257 AVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDqlQENLSRVNLSEEDKEKLQKLTELKESLEctvdQEQKRSSALEKE 1336
Cdd:TIGR02169 313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIE--EERKRRDKLTEEYAELKEELEDLRAELE----EVDKEFAETRDE 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1337 LAEFKEVLKMTKKELNEYENRELNL-----RQDIKNNHLEMDIPVstLIKKIDDLTAKLETASSKclhlgkknqllqqel 1411
Cdd:TIGR02169 387 LKDYREKLEKLKREINELKRELDRLqeelqRLSEELADLNAAIAG--IEAKINELEEEKEDKALE--------------- 449
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 568941650 1412 llmrtIQKKCGKLEKNKKQL---EQEVVNLRSHMEKNMVEHSQAQQYAREVEERARQ 1465
Cdd:TIGR02169 450 -----IKKQEWKLEQLAADLskyEQELYDLKEEYDRVEKELSKLQRELAEAEAQARA 501
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
729-1566 |
4.89e-13 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 74.72 E-value: 4.89e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 729 KLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEAR- 807
Cdd:TIGR02169 217 LKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKi 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 808 QQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSReqnarmlqdgilashlcKQKEIEMTQKKMTSEvsvshEKEKDl 887
Cdd:TIGR02169 297 GELEAEIASLERSIAEKERELEDAEERLAKLEAEIDK-----------------LLAEIEELEREIEEE-----RKRRD- 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 888 lhknqRLQDEVAVLRLEMDTIKSHNQEKEKRYlediKIANEKNDNLQrmvklneetftKTIFQYTGQLNSLKAEntmlss 967
Cdd:TIGR02169 354 -----KLTEEYAELKEELEDLRAELEEVDKEF----AETRDELKDYR-----------EKLEKLKREINELKRE------ 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 968 kLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMnfdmsnlrdnnEVLSQQLSKTE 1047
Cdd:TIGR02169 408 -LDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADL-----------SKYEQELYDLK 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1048 RKLNSLEIEFHhtkdELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEER--------------- 1112
Cdd:TIGR02169 476 EEYDRVEKELS----KLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaagnrlnn 551
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1113 -------------------------------LAQLQSENTLLRQQ--LDDAANKAESKDKTIVNIQDQFQDVLTRFQAES 1159
Cdd:TIGR02169 552 vvveddavakeaiellkrrkagratflplnkMRDERRDLSILSEDgvIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIEA 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1160 QRH---SLRLEDRNQELVSECSHL----RERLCQYENEKAEREVVvrqlqQELADTLKKQSMSEASLEVSSRYRSNLEEE 1232
Cdd:TIGR02169 632 ARRlmgKYRMVTLEGELFEKSGAMtggsRAPRGGILFSRSEPAEL-----QRLRERLEGLKRELSSLQSELRRIENRLDE 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1233 AR----DLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEED--- 1305
Cdd:TIGR02169 707 LSqelsDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlea 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1306 ---KEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEMDipvsTLIKK 1382
Cdd:TIGR02169 787 rlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIE----NLNGK 862
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1383 IDDLTAKLETASSKCLHLGKKNQLLQQELLLMrtiQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEER 1462
Cdd:TIGR02169 863 KEELEEELEELEAALRDLESRLGDLKKERDEL---EAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDP 939
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1463 ARQDL--------VEKLKQVNLFLQAQAASQESLEQLRENSNASVrsqmELRIKDLESQLYRMKAQEDFDKIELEKYKQL 1534
Cdd:TIGR02169 940 KGEDEeipeeelsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEV----LKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
|
890 900 910
....*....|....*....|....*....|...
gi 568941650 1535 YQEEF-RARKSLSSKLNKTSEKLEEASSKLLLE 1566
Cdd:TIGR02169 1016 KREVFmEAFEAINENFNEIFAELSGGTGELILE 1048
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
62-210 |
5.35e-13 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 73.16 E-value: 5.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 62 KVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTAL-----IKAVQCQEEECAAILLDH 136
Cdd:PHA03100 16 KNIKYIIMEDDLNDYSYKKPVLPLYLAKEARNIDVVKILLDNGADINSSTKNNSTPLhylsnIKYNLTDVKEIVKLLLEY 95
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568941650 137 GADPNVMDSSGNTALHYAVY--SENTSMAAKLLAHNANIEAKNKDDLTPMLLAVK--ENKQHIVEFLVKKKASIHAVD 210
Cdd:PHA03100 96 GANVNAPDNNGITPLLYAISkkSNSYSIVEYLLDNGANVNIKNSDGENLLHLYLEsnKIDLKILKLLIDKGVDINAKN 173
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
771-1342 |
3.11e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.89 E-value: 3.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 771 ALKQEEEKR---------RSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQ 841
Cdd:COG1196 217 ELKEELKELeaellllklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 842 LSREQNARMLQDGilashlcKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLE 921
Cdd:COG1196 297 LARLEQDIARLEE-------RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 922 DIKIANEKNDNLQRmvklneetFTKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQ 1001
Cdd:COG1196 370 AEAELAEAEEELEE--------LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1002 TAKRDLEIAFQRARDEwfrvkdkmnfdmsnlRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQT 1081
Cdd:COG1196 442 EALEEAAEEEAELEEE---------------EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGF 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1082 QCQMKEVEHmfQDEQGKVSKFMGKQESIEERLAQLQsENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAES-Q 1160
Cdd:COG1196 507 LEGVKAALL--LAGLRGLAGAVAVLIGVEAAYEAAL-EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKiR 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1161 RHSLRLEDRNQELVSECSHLRERLCQYENEKAER---EVVVRQLQQELADTLKKQSMS------EASLEVSSRYRSNLEE 1231
Cdd:COG1196 584 ARAALAAALARGAIGAAVDLVASDLREADARYYVlgdTLLGRTLVAARLEAALRRAVTlagrlrEVTLEGEGGSAGGSLT 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1232 EARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQK 1311
Cdd:COG1196 664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
|
570 580 590
....*....|....*....|....*....|.
gi 568941650 1312 LTELKESLECTVDQEQKRSSALEKELAEFKE 1342
Cdd:COG1196 744 EEELLEEEALEELPEPPDLEELERELERLER 774
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
772-1433 |
4.04e-12 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 71.54 E-value: 4.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 772 LKQEEEKRRSADQLSEKTSEQLRRKGEQcQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNEtQRQLSReqnarml 851
Cdd:TIGR00618 224 LEKELKHLREALQQTQQSHAYLTQKREA-QEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINR-ARKAAP------- 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 852 qdgiLASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKryledIKIANEKnD 931
Cdd:TIGR00618 295 ----LAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIH-----IRDAHEV-A 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 932 NLQRMVKLNEETFTKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAF 1011
Cdd:TIGR00618 365 TSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCA 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1012 QRARDEWFRVKDKmNFDMSNLRDNNEVLSQQLSKTE---RKLNSLEIEFHHTKDELREKTLALKHAQRDLSQ-------- 1080
Cdd:TIGR00618 445 AAITCTAQCEKLE-KIHLQESAQSLKEREQQLQTKEqihLQETRKKAVVLARLLELQEEPCPLCGSCIHPNParqdidnp 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1081 --TQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAE 1158
Cdd:TIGR00618 524 gpLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKL 603
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1159 SQ-RHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEV------SSRYRSNLEE 1231
Cdd:TIGR00618 604 SEaEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIrvlpkeLLASRQLALQ 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1232 EARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRvnlseEDKEKLQK 1311
Cdd:TIGR00618 684 KMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMH-----QARTVLKA 758
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1312 LTELKE--SLECTVD-QEQKRSSALEKELAEFKEVLKMTKKELNEYENRelnLRQDIKNNHLEMDIPVSTLIKKIDDLTA 1388
Cdd:TIGR00618 759 RTEAHFnnNEEVTAAlQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAE---IGQEIPSDEDILNLQCETLVQEEEQFLS 835
|
650 660 670 680
....*....|....*....|....*....|....*....|....*
gi 568941650 1389 KLETASSKclhlgkknqllqqelllMRTIQKKCGKLEKNKKQLEQ 1433
Cdd:TIGR00618 836 RLEEKSAT-----------------LGEITHQLLKYEECSKQLAQ 863
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1032-1512 |
5.18e-12 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 71.22 E-value: 5.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1032 LRDNNEVLSQQLSKTERK--------LNSLEIEFHHTKDEL------REKTLALKHAQRDL----SQTQCQMKEVEHMFQ 1093
Cdd:PRK02224 182 LSDQRGSLDQLKAQIEEKeekdlherLNGLESELAELDEEIeryeeqREQARETRDEADEVleehEERREELETLEAEIE 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1094 DEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRF------------------ 1155
Cdd:PRK02224 262 DLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDeelrdrleecrvaaqahn 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1156 -QAESQRHS-LRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEA 1233
Cdd:PRK02224 342 eEAESLREDaDDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1234 RDLKKKLGQLRSQLQEARDQHREA---------------------VHHAEKMEDHLQKLELEKSKFEITI---------- 1282
Cdd:PRK02224 422 DELREREAELEATLRTARERVEEAealleagkcpecgqpvegsphVETIEEDRERVEELEAELEDLEEEVeeveerlera 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1283 ---KKQSEEIDQLQENLSRVN--------LSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKEL 1351
Cdd:PRK02224 502 edlVEAEDRIERLEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKL 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1352 NEYENRELNLRQdiknnhlemdipVSTLIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMRTiqkkcgklekNKKQL 1431
Cdd:PRK02224 582 AELKERIESLER------------IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRE----------RKREL 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1432 EQEVVNLRshMEKNMVEHSQAQQYAREVEERARQdLVEKLKQVNLFLQAQAASQESLEQLRENsnasvRSQMELRIKDLE 1511
Cdd:PRK02224 640 EAEFDEAR--IEEAREDKERAEEYLEQVEEKLDE-LREERDDLQAEIGAVENELEELEELRER-----REALENRVEALE 711
|
.
gi 568941650 1512 S 1512
Cdd:PRK02224 712 A 712
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
864-1391 |
7.32e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 70.74 E-value: 7.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 864 KEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTI-KSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEE 942
Cdd:COG1196 235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELeLELEEAQAEEYELLAELARLEQDIARLEERRREL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 943 TftktifqytGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVK 1022
Cdd:COG1196 315 E---------ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELA 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1023 DkmnfDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKF 1102
Cdd:COG1196 386 E----ELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1103 MGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSEC-SHLR 1181
Cdd:COG1196 462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYeAALE 541
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1182 ERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSN---------------LEEEARDLKKKLGQLRSQ 1246
Cdd:COG1196 542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALaaalargaigaavdlVASDLREADARYYVLGDT 621
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1247 LQEARDQHREAVHHAEKMEDHLQKLE-------------LEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLT 1313
Cdd:COG1196 622 LLGRTLVAARLEAALRRAVTLAGRLRevtlegeggsaggSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568941650 1314 ELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEMDIpvSTLIKKIDDLTAKLE 1391
Cdd:COG1196 702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL--EELERELERLEREIE 777
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
726-1365 |
7.90e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 70.48 E-value: 7.90e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 726 LTGKLKRM-ENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRS----ADQLSEKTSEQLRRKgEQC 800
Cdd:TIGR02169 277 LNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKllaeIEELEREIEEERKRR-DKL 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 801 QSEVEAR-----------QQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQ-----------NARMLQDGILAS 858
Cdd:TIGR02169 356 TEEYAELkeeledlraelEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQeelqrlseelaDLNAAIAGIEAK 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 859 HL-------CKQKEI-EMTQKKMTSEVSVSHEKEK--DLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANE 928
Cdd:TIGR02169 436 INeleeekeDKALEIkKQEWKLEQLAADLSKYEQElyDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEV 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 929 KNDNLQ-------RMVKLNEETFTKTIFQYTGQLNS---------------LKAEN----TMLS-SKLDNEKQNKERLET 981
Cdd:TIGR02169 516 LKASIQgvhgtvaQLGSVGERYATAIEVAAGNRLNNvvveddavakeaielLKRRKagraTFLPlNKMRDERRDLSILSE 595
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 982 DV------------ESFRSRLASALHDH---AEIQTAKRDLEIA---------FQR--ARDEWFRVKDKMNFDMSNLRDN 1035
Cdd:TIGR02169 596 DGvigfavdlvefdPKYEPAFKYVFGDTlvvEDIEAARRLMGKYrmvtlegelFEKsgAMTGGSRAPRGGILFSRSEPAE 675
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1036 NEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQcqmKEVEHMFQDEQgkvsKFMGKQESIEERLAQ 1115
Cdd:TIGR02169 676 LQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE---KEIEQLEQEEE----KLKERLEELEEDLSS 748
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1116 LQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTR----FQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEK 1191
Cdd:TIGR02169 749 LEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARlshsRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEK 828
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1192 AEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKL 1271
Cdd:TIGR02169 829 EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEEL 908
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1272 ELEKSKFEITIKKQSEEIDQLQENLSRV-------------NLSEED-KEKLQKLTELKESLE---CTVDQEQKRSSALE 1334
Cdd:TIGR02169 909 EAQIEKKRKRLSELKAKLEALEEELSEIedpkgedeeipeeELSLEDvQAELQRVEEEIRALEpvnMLAIQEYEEVLKRL 988
|
730 740 750
....*....|....*....|....*....|.
gi 568941650 1335 KELAEFKEVLKMTKKELNEYENRELNLRQDI 1365
Cdd:TIGR02169 989 DELKEKRAKLEEERKAILERIEEYEKKKREV 1019
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
795-1520 |
1.38e-11 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 69.82 E-value: 1.38e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 795 RKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQNARMLQDGILASHLCKQKEIEMTQKKMT 874
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 875 SEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQE----------KEKRYLEDIKIANEKNDNLQRMVKLNEEtf 944
Cdd:pfam01576 82 SRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKlqlekvtteaKIKKLEEDILLLEDQNSKLSKERKLLEE-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 945 tkTIFQYTGQLnslkAENTMLSSKLDNEKQNKERLETDVEsfrSRLASALHDHAEIQTAKRDLEIAFQRARDEwfrvkdk 1024
Cdd:pfam01576 160 --RISEFTSNL----AEEEEKAKSLSKLKNKHEAMISDLE---ERLKKEEKGRQELEKAKRKLEGESTDLQEQ------- 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1025 mnfdMSNLRDNNEVLSQQLSKTERKLNSLEiefhhtkDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMG 1104
Cdd:pfam01576 224 ----IAELQAQIAELRAQLAKKEEELQAAL-------ARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEK 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1105 KQESIEERLAQLQSEntlLRQQLDDAANKAESKDKtivniQDQFQDVLTR-FQAESQRHSLRLEDRNQELVSECSHLRER 1183
Cdd:pfam01576 293 QRRDLGEELEALKTE---LEDTLDTTAAQQELRSK-----REQEVTELKKaLEEETRSHEAQLQEMRQKHTQALEELTEQ 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1184 LCQYENEKAEREVVVRQLQQELADTlkkqsmsEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEK 1263
Cdd:pfam01576 365 LEQAKRNKANLEKAKQALESENAEL-------QAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSK 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1264 MEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVN--LSEEDKEKLQ------KLTELKESLECTVDQEQKRSSALEK 1335
Cdd:pfam01576 438 LQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQelLQEETRQKLNlstrlrQLEDERNSLQEQLEEEEEAKRNVER 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1336 ELAEFKEVLKMTKKELNEYENRELNLRQDIKNnhlemdipvstLIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMR 1415
Cdd:pfam01576 518 QLSTLQAQLSDMKKKLEEDAGTLEALEEGKKR-----------LQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLL 586
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1416 TIQKK----CGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVE------ERARQDLVEKLKQVNLFLQAQAASQ 1485
Cdd:pfam01576 587 VDLDHqrqlVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKEtralslARALEEALEAKEELERTNKQLRAEM 666
|
730 740 750
....*....|....*....|....*....|....*
gi 568941650 1486 ESLEQLRENSNASVRsQMELRIKDLESQLYRMKAQ 1520
Cdd:pfam01576 667 EDLVSSKDDVGKNVH-ELERSKRALEQQVEEMKTQ 700
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
730-1515 |
1.46e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 69.76 E-value: 1.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 730 LKRMENKYKGLQKEMSETEEVKsrlEHEKVGWEQELCRLRFALKQEEEKRrsaDQLSEktseqLRRKGEQCQSEVeaRQQ 809
Cdd:pfam15921 80 LEEYSHQVKDLQRRLNESNELH---EKQKFYLRQSVIDLQTKLQEMQMER---DAMAD-----IRRRESQSQEDL--RNQ 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 810 LEASLRtlemELKTVKSHLNQVLEERNETQRQLSReqnarmlqdgILASHLCKQKEI--------EMTQKKMTSEVSVSH 881
Cdd:pfam15921 147 LQNTVH----ELEAAKCLKEDMLEDSNTQIEQLRK----------MMLSHEGVLQEIrsilvdfeEASGKKIYEHDSMST 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 882 EKEKDL---LHKNQR-LQDEVAVLRL-------EMDTIKSHNQEKEKRYLEdikianEKNDNLQRMVKLNE---ETFTKT 947
Cdd:pfam15921 213 MHFRSLgsaISKILReLDTEISYLKGrifpvedQLEALKSESQNKIELLLQ------QHQDRIEQLISEHEveiTGLTEK 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 948 IFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHD-----HAEIQTAKRDLEIA---FQRARDEwf 1019
Cdd:pfam15921 287 ASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREakrmyEDKIEELEKQLVLAnseLTEARTE-- 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1020 rvKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQ----DE 1095
Cdd:pfam15921 365 --RDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKamksEC 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1096 QGKVSKFM----GKQESIEE---RLAQLQSENTLLRQQLDDAANKA---ESKDKTIVNIQDQFQDVLTRFQAESQRHSlR 1165
Cdd:pfam15921 443 QGQMERQMaaiqGKNESLEKvssLTAQLESTKEMLRKVVEELTAKKmtlESSERTVSDLTASLQEKERAIEATNAEIT-K 521
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1166 LEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQEladtlkkqsmsEASLEVssryrsnLEEEARDLKKKLGQlrs 1245
Cdd:pfam15921 522 LRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEK-----------DKVIEI-------LRQQIENMTQLVGQ--- 580
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1246 qlqEARDQHREAVHHAEkMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLseedkEKLQKLTELKESLECTVDQ 1325
Cdd:pfam15921 581 ---HGRTAGAMQVEKAQ-LEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLEL-----EKVKLVNAGSERLRAVKDI 651
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1326 EQKRSSALEKelaefkevLKMTKKELNEYENRELNLRQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHL-GKKN 1404
Cdd:pfam15921 652 KQERDQLLNE--------VKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMeGSDG 723
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1405 QLLQQELLLMRTIQKKCGKLE--KNKKQLEQEVV---NLRSHM---EKNMVEH------SQAQQYAREVEERARQDLVEK 1470
Cdd:pfam15921 724 HAMKVAMGMQKQITAKRGQIDalQSKIQFLEEAMtnaNKEKHFlkeEKNKLSQelstvaTEKNKMAGELEVLRSQERRLK 803
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|
gi 568941650 1471 LKQVNLFLQAQAASQESLE-----QLRENSNASVRSQMELRIKDLESQLY 1515
Cdd:pfam15921 804 EKVANMEVALDKASLQFAEcqdiiQRQEQESVRLKLQHTLDVKELQGPGY 853
|
|
| PHA03100 |
PHA03100 |
ankyrin repeat protein; Provisional |
41-211 |
1.69e-11 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 68.54 E-value: 1.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 41 YHIHDKDMgkihkaASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAY--GHPEVVTLLVERKCEIDARDSESSTAL 118
Cdd:PHA03100 72 LHYLSNIK------YNLTDVKEIVKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEYLLDNGANVNIKNSDGENLL 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 119 IKAVQC--QEEECAAILLDHGADPNVMDS----------------SGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDD 180
Cdd:PHA03100 146 HLYLESnkIDLKILKLLIDKGVDINAKNRvnyllsygvpinikdvYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYG 225
|
170 180 190
....*....|....*....|....*....|.
gi 568941650 181 LTPMLLAVKENKQHIVEFLVKKKASIHAVDQ 211
Cdd:PHA03100 226 DTPLHIAILNNNKEIFKLLLNNGPSIKTIIE 256
|
|
| PLN03192 |
PLN03192 |
Voltage-dependent potassium channel; Provisional |
54-277 |
1.99e-11 |
|
Voltage-dependent potassium channel; Provisional
Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 69.13 E-value: 1.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 54 AASVGDVAKVQHILILGKSGvNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAIL 133
Cdd:PLN03192 532 VASTGNAALLEELLKAKLDP-DIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRIL 610
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 134 --LDHGADPNvmdsSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAV-- 209
Cdd:PLN03192 611 yhFASISDPH----AAGDLLCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVDKAnt 686
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568941650 210 DQLGSNRQMFEYDGKRlQRSENSNPVDNGSEDGSLTRSYNTPGPADSWPTSdeedynFDNKNVPKINL 277
Cdd:PLN03192 687 DDDFSPTELRELLQKR-ELGHSITIVDSVPADEPDLGRDGGSRPGRLQGTS------SDNQCRPRVSI 747
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1105-1563 |
4.11e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 68.17 E-value: 4.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1105 KQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQaesqrhslRLEDRNQELVSECSHLRERL 1184
Cdd:PRK03918 159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREIN--------EISSELPELREELEKLEKEV 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1185 CQYENEKAEREvvvrQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSqLQEARDQHREAVHHAEKM 1264
Cdd:PRK03918 231 KELEELKEEIE----ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE-LKEKAEEYIKLSEFYEEY 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1265 EDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVN-LSEEDKEKLQKLTELKESLEC--TVDQEQKRSSALEKELAEfk 1341
Cdd:PRK03918 306 LDELREIEKRLSRLEEEINGIEERIKELEEKEERLEeLKKKLKELEKRLEELEERHELyeEAKAKKEELERLKKRLTG-- 383
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1342 EVLKMTKKELNEYENRELNLRQDIKNnHLEMDIPVSTLIKKIDDLTAKLETASSKCLHLGK------KNQLLQQELLLMR 1415
Cdd:PRK03918 384 LTPEKLEKELEELEKAKEEIEEEISK-ITARIGELKKEIKELKKAIEELKKAKGKCPVCGRelteehRKELLEEYTAELK 462
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1416 TIQKKCGKLEKNKKQLEQEVVNLRSHMEK------------------------NMVEHSQAQQYAREVEERARQ------ 1465
Cdd:PRK03918 463 RIEKELKEIEEKERKLRKELRELEKVLKKeseliklkelaeqlkeleeklkkyNLEELEKKAEEYEKLKEKLIKlkgeik 542
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1466 DLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQMELRIKDLESQLYRMKAQEDFDK--IELEKYKQLYQEEFRARK 1543
Cdd:PRK03918 543 SLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNeyLELKDAEKELEREEKELK 622
|
490 500
....*....|....*....|
gi 568941650 1544 SLSSKLNKTSEKLEEASSKL 1563
Cdd:PRK03918 623 KLEEELDKAFEELAETEKRL 642
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
74-214 |
4.99e-11 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 66.91 E-value: 4.99e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 74 VNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHY 153
Cdd:PHA02874 117 VNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHN 196
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568941650 154 AVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQhIVEFLVkKKASIHAVDQLGS 214
Cdd:PHA02874 197 AAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIIHNRS-AIELLI-NNASINDQDIDGS 255
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
726-1252 |
7.02e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 67.45 E-value: 7.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 726 LTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVE 805
Cdd:pfam15921 375 LDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 806 ARQQLEASLRTLEMELKTVKSHLNQVLEERneTQRQLSREQNARMLQDgILASHLCKQKEIEMTQKKMTSEVSVSHEKEK 885
Cdd:pfam15921 455 GKNESLEKVSSLTAQLESTKEMLRKVVEEL--TAKKMTLESSERTVSD-LTASLQEKERAIEATNAEITKLRSRVDLKLQ 531
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 886 DLLH-KNQrlQDEVAVLRLEMDTIKSHNQEKEKRyledIKIANEKNDNLQRMVKLNEETFTKTIF---QYTGQLNSLK-- 959
Cdd:pfam15921 532 ELQHlKNE--GDHLRNVQTECEALKLQMAEKDKV----IEILRQQIENMTQLVGQHGRTAGAMQVekaQLEKEINDRRle 605
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 960 -AENTMLSSKLDNEKQNKERLETDVESFRSRLASA----LHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRD 1034
Cdd:pfam15921 606 lQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAgserLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRN 685
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1035 NNEVLSQQLSKTERKLNSLEIEFHHTKDELR----------------EKTLALKHAQRDLSQTQCQMKEV--------EH 1090
Cdd:pfam15921 686 KSEEMETTTNKLKMQLKSAQSELEQTRNTLKsmegsdghamkvamgmQKQITAKRGQIDALQSKIQFLEEamtnankeKH 765
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1091 MFQDEQGKVSKFMGKQESIEERLA-QLQSENTLLRQQLDDAANKAESKDKTIVNIQdQFQDVLTRFQAESQR----HSLR 1165
Cdd:pfam15921 766 FLKEEKNKLSQELSTVATEKNKMAgELEVLRSQERRLKEKVANMEVALDKASLQFA-ECQDIIQRQEQESVRlklqHTLD 844
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1166 LEDRNQELVSECSHLRERLCQYENEKAEREVVVRQlqQELADTLKKQSMSEASLEvssryrsnlEEEARDLKKKLGQLRS 1245
Cdd:pfam15921 845 VKELQGPGYTSNSSMKPRLLQPASFTRTHSNVPSS--QSTASFLSHHSRKTNALK---------EDPTRDLKQLLQELRS 913
|
....*..
gi 568941650 1246 QLQEARD 1252
Cdd:pfam15921 914 VINEEPT 920
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
730-1392 |
7.32e-11 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 67.35 E-value: 7.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 730 LKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQcqseveaRQQ 809
Cdd:TIGR04523 49 LKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQ-------KNK 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 810 LEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQNArmlqdgilASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLh 889
Cdd:TIGR04523 122 LEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNK--------YNDLKKQKEELENELNLLEKEKLNIQKNIDKI- 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 890 KNQRLQDEVAVLRLEmdTIKSHNQEKEKRYLEDIKIANEKNDNLQRmvKLNEETFTKTIFQYT-GQLNSLKAENTMLSSK 968
Cdd:TIGR04523 193 KNKLLKLELLLSNLK--KKIQKNKSLESQISELKKQNNQLKDNIEK--KQQEINEKTTEISNTqTQLNQLKDEQNKIKKQ 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 969 LDNEKQNKERLETDVESFRsrlasalhdhAEIQTAKRDLEIAFQRARDEWFRvkdKMNFDMSNLRDNNEVLSQQLSKTER 1048
Cdd:TIGR04523 269 LSEKQKELEQNNKKIKELE----------KQLNQLKSEISDLNNQKEQDWNK---ELKSELKNQEKKLEEIQNQISQNNK 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1049 KLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHmfqdeqgkvskfmgKQESIEERLAQLQSENTLLRQQLD 1128
Cdd:TIGR04523 336 IISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK--------------ENQSYKQEIKNLESQINDLESKIQ 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1129 DAANKAESKDKTIVNIQDQFQdvltrfqaesqrhslRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQeLADT 1208
Cdd:TIGR04523 402 NQEKLNQQKDEQIKKLQQEKE---------------LLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDN-TRES 465
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1209 LKKQsMSEASLEVSSrYRSNLEEEARDLKKK---LGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQ 1285
Cdd:TIGR04523 466 LETQ-LKVLSRSINK-IKQNLEQKQKELKSKekeLKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDL 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1286 SEEIDQLQENLSRVNLSEEDKEKLQKLTELKEslecTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDI 1365
Cdd:TIGR04523 544 EDELNKDDFELKKENLEKEIDEKNKEIEELKQ----TQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619
|
650 660
....*....|....*....|....*..
gi 568941650 1366 KNNHLEMDiPVSTLIKKIDDLTAKLET 1392
Cdd:TIGR04523 620 EKAKKENE-KLSSIIKNIKSKKNKLKQ 645
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
999-1579 |
7.42e-11 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 67.56 E-value: 7.42e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 999 EIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRdnnevlsQQLSKTERKLNSLEiEFHHTKDELREKTLALKHAQRDL 1078
Cdd:pfam12128 280 ERQETSAELNQLLRTLDDQWKEKRDELNGELSAAD-------AAVAKDRSELEALE-DQHGAFLDADIETAAADQEQLPS 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1079 SQTQCQMKEVEH-MFQDEQGKVskfmgkQESIEERLAQLQSEN-TLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQ 1156
Cdd:pfam12128 352 WQSELENLEERLkALTGKHQDV------TAKYNRRRSKIKEQNnRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELR 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1157 AESQRHSLRLEDRNQELVSECSHLRERL--CQYENE----KAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLE 1230
Cdd:pfam12128 426 EQLEAGKLEFNEEEYRLKSRLGELKLRLnqATATPElllqLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQAS 505
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1231 EEARDLKKKLGQLRSQLQEARDQHREAVH--------HAEKMEDHLQKL---EL------------EKSKFEITIKKQSE 1287
Cdd:pfam12128 506 EALRQASRRLEERQSALDELELQLFPQAGtllhflrkEAPDWEQSIGKVispELlhrtdldpevwdGSVGGELNLYGVKL 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1288 EIDQLQENlSRVNLSEEDKEKLQKLTElkeslecTVDQEQKRSSALEKELAEFKEVLKMTKKELNE----YENRELNLRQ 1363
Cdd:pfam12128 586 DLKRIDVP-EWAASEEELRERLDKAEE-------ALQSAREKQAAAEEQLVQANGELEKASREETFartaLKNARLDLRR 657
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1364 diknnhlemdipvstlikkiddLTAKLETASSKClhlgkknqlLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRSHME 1443
Cdd:pfam12128 658 ----------------------LFDEKQSEKDKK---------NKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQK 706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1444 KNMVEHSQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQES-LEQLRENSNAS------VRSQMELRIKDLESQLYR 1516
Cdd:pfam12128 707 EQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKaLETWYKRDLASlgvdpdVIAKLKREIRTLERKIER 786
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568941650 1517 MKAqedfDKIELEKYKQLYQEEFRARK-SLSSKLNKTSEKLEEASSKLLLEEQQNRSLLSTLST 1579
Cdd:pfam12128 787 IAV----RRQEVLRYFDWYQETWLQRRpRLATQLSNIERAISELQQQLARLIADTKLRRAKLEM 846
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
59-210 |
1.31e-10 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 66.24 E-value: 1.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 59 DVAKVQHILILGkSGVNDRDKKDRTALHLACAYG-HPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHG 137
Cdd:PHA02876 320 DTENIRTLIMLG-ADVNAADRLYITPLHQASTLDrNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYG 398
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568941650 138 ADPNVMDSSGNTALHYAVYSENTSMAAK-LLAHNANIEAKNKDDLTPMLLAVKEN-KQHIVEFLVKKKASIHAVD 210
Cdd:PHA02876 399 ADIEALSQKIGTALHFALCGTNPYMSVKtLIDRGANVNSKNKDLSTPLHYACKKNcKLDVIEMLLDNGADVNAIN 473
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
736-1571 |
5.65e-10 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 64.61 E-value: 5.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 736 KYKGLQKEMSETEEVKSRLehekvGWEQELCRLRFALKQEEEKRRSADQLSEKtsEQLRRKGEQCQSEVEARQQLEASLR 815
Cdd:pfam02463 171 KKEALKKLIEETENLAELI-----IDLEELKLQELKLKEQAKKALEYYQLKEK--LELEEEYLLYLDYLKLNEERIDLLQ 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 816 TLEMELKTVKSHLNQVLEERNETQRQLSREQNARMLQDGILASHLC-KQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRL 894
Cdd:pfam02463 244 ELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKlLAKEEEELKSELLKLERRKVDDEEKLKESEKEK 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 895 QDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKNDNLQRMVKL--NEETFTKTIFQYTGQLNSLKAENTMLSSKLDNE 972
Cdd:pfam02463 324 KKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLeqLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 973 KQNKERLetdvesfrSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEV-LSQQLSKTERKLN 1051
Cdd:pfam02463 404 EKEAQLL--------LELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLkDELELKKSEDLLK 475
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1052 SLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQD-EQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDA 1130
Cdd:pfam02463 476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDgVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSA 555
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1131 ANKAESKDKTIVNIQDQFQDVLTRFQAESqRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLK 1210
Cdd:pfam02463 556 TADEVEERQKLVRALTELPLGARKLRLLI-PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTEL 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1211 KQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARdqhreavhHAEKMEDHLQKLELEKSKFEITIKKQSEEID 1290
Cdd:pfam02463 635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKEL--------LEIQELQEKAESELAKEEILRRQLEIKKKEQ 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1291 QLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEF--KEVLKMTKKELNEYENRELNLRQDIKNN 1368
Cdd:pfam02463 707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRlkKEEKEEEKSELSLKEKELAEEREKTEKL 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1369 HLEMDIpVSTLIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVE 1448
Cdd:pfam02463 787 KVEEEK-EEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITK 865
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1449 HSQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQL------RENSNASVRSQMELRIKDLESQLYRMKAQED 1522
Cdd:pfam02463 866 EELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKlnlleeKENEIEERIKEEAEILLKYEEEPEELLLEEA 945
|
810 820 830 840
....*....|....*....|....*....|....*....|....*....
gi 568941650 1523 FDKIELEKYKQlyQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQNR 1571
Cdd:pfam02463 946 DEKEKEENNKE--EEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNK 992
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
43-190 |
1.60e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 62.20 E-value: 1.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 43 IHDKDMGK--IHKAASVGDvAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIK 120
Cdd:PHA02878 162 MKDRHKGNtaLHYATENKD-QRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLHI 240
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568941650 121 AV-QCQEEECAAILLDHGADPNVMDS-SGNTALHYAVYSENTSMAakLLAHNANIEAKNKDDLTPMLLAVKE 190
Cdd:PHA02878 241 SVgYCKDYDILKLLLEHGVDVNAKSYiLGLTALHSSIKSERKLKL--LLEYGADINSLNSYKLTPLSSAVKQ 310
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
715-1541 |
1.89e-09 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 62.68 E-value: 1.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 715 LIELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLR 794
Cdd:pfam02463 192 LEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVL 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 795 RKGEQCQSEVEARQQLEASLRTLEMELKTVKSHL-NQVLEERNETQRQLSREQNARMLQDGILASHLCKQKEIEMTQKKM 873
Cdd:pfam02463 272 KENKEEEKEKKLQEEELKLLAKEEEELKSELLKLeRRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKR 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 874 TSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKS----HNQEKEKRYlEDIKIANEKNDNLQRMVKLNEETFTKtif 949
Cdd:pfam02463 352 EAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSaaklKEEELELKS-EEEKEAQLLLELARQLEDLLKEEKKE--- 427
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 950 qytgqlnSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMnFDM 1029
Cdd:pfam02463 428 -------ELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLE-ERS 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1030 SNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHA-----QRDLSQTQCQMKEVEHMFQ------DEQGK 1098
Cdd:pfam02463 500 QKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAistavIVEVSATADEVEERQKLVRaltelpLGARK 579
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1099 VSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLtrfQAESQRHSLRLEDRNQELVSecs 1178
Cdd:pfam02463 580 LRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTE---LTKLKESAKAKESGLRKGVS--- 653
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1179 hlrerLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAV 1258
Cdd:pfam02463 654 -----LEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQ 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1259 HHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVnLSEEDKEKLQKLTELKESLEctvDQEQKRSSALEKELA 1338
Cdd:pfam02463 729 EAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSEL-SLKEKELAEEREKTEKLKVE---EEKEEKLKAQEEELR 804
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1339 EFKEVLKMTKKELNEYENRELNL--RQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMRT 1416
Cdd:pfam02463 805 ALEEELKEEAELLEEEQLLIEQEekIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKL 884
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1417 IQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEERaRQDLVEKLKQVNLFLQAQAASQESLEQLRENSN 1496
Cdd:pfam02463 885 KDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEIL-LKYEEEPEELLLEEADEKEKEENNKEEEEERNK 963
|
810 820 830 840
....*....|....*....|....*....|....*....|....*..
gi 568941650 1497 ASVRSQMELRIKDLES--QLYRMKAQEDFDKIELEKYKQLYQEEFRA 1541
Cdd:pfam02463 964 RLLLAKEELGKVNLMAieEFEEKEERYNKDELEKERLEEEKKKLIRA 1010
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1167-1578 |
1.93e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 62.77 E-value: 1.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1167 EDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKklgqLRSQ 1246
Cdd:PRK03918 164 YKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE----LKEE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1247 LQEARDQhreavhhAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQE 1326
Cdd:PRK03918 240 IEELEKE-------LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREI 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1327 QKRSSALEKELAEFKEVLK---MTKKELNEYENRELNLRQD---IKNNHLEMDiPVSTLIKKIDDLTAKLetassKCLHL 1400
Cdd:PRK03918 313 EKRLSRLEEEINGIEERIKeleEKEERLEELKKKLKELEKRleeLEERHELYE-EAKAKKEELERLKKRL-----TGLTP 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1401 GKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEERARQDLVEK-LKQVNLFLQ 1479
Cdd:PRK03918 387 EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEyTAELKRIEK 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1480 AQAASQESLEQLREN-----------SNASVRSQMELRIKDLESQLyrmkaqEDFDKIELEKYKQLYQ---EEFRARKSL 1545
Cdd:PRK03918 467 ELKEIEEKERKLRKElrelekvlkkeSELIKLKELAEQLKELEEKL------KKYNLEELEKKAEEYEklkEKLIKLKGE 540
|
410 420 430
....*....|....*....|....*....|...
gi 568941650 1546 SSKLNKTSEKLEEASSKLLLEEQQNRSLLSTLS 1578
Cdd:PRK03918 541 IKSLKKELEKLEELKKKLAELEKKLDELEEELA 573
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
772-1558 |
2.18e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 62.76 E-value: 2.18e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 772 LKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRtlemelKTVKSHLNQvLEERNETQRQLSREQNARML 851
Cdd:TIGR00606 194 VRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSR------EIVKSYENE-LDPLKNRLKEIEHNLSKIMK 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 852 QDGILASHLCKQKEIEMTQK----KMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMD-TIKSHNQEKEKRYLEDIKIA 926
Cdd:TIGR00606 267 LDNEIKALKSRKKQMEKDNSelelKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQrELEKLNKERRLLNQEKTELL 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 927 NEkndnlQRMVKLNEETFTKTIFQYTG--QLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQtak 1004
Cdd:TIGR00606 347 VE-----QGRLQLQADRHQEHIRARDSliQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQ--- 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1005 rDLEIAFQRARDEwfrVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEiEFHHTKDELREKTLALKHAQRDLSQ---- 1080
Cdd:TIGR00606 419 -SKERLKQEQADE---IRDEKKGLGRTIELKKEILEKKQEELKFVIKELQ-QLEGSSDRILELDQELRKAERELSKaekn 493
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1081 --TQCQMKEVEHMfQDEQGKVSKfmgKQESIEERLAQLQSENTLLRQQLDDAANKAEsKDKTIVNIQDQFQDVLTRF--- 1155
Cdd:TIGR00606 494 slTETLKKEVKSL-QNEKADLDR---KLRKLDQEMEQLNHHTTTRTQMEMLTKDKMD-KDEQIRKIKSRHSDELTSLlgy 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1156 -----QAESQRHSLR-----LEDRNQELVSECSHLRERLCQYENEKAER--------------------EVVVRQLQQEL 1205
Cdd:TIGR00606 569 fpnkkQLEDWLHSKSkeinqTRDRLAKLNKELASLEQNKNHINNELESKeeqlssyedklfdvcgsqdeESDLERLKEEI 648
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1206 ADTLKKQSMSEASLEVSSRYRSNLEEEARD---LKKKLGQLRSQLQEA----RDQHREAVHHAEKMEDHLQKLELEKSKF 1278
Cdd:TIGR00606 649 EKSSKQRAMLAGATAVYSQFITQLTDENQSccpVCQRVFQTEAELQEFisdlQSKLRLAPDKLKSTESELKKKEKRRDEM 728
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1279 EITIKKQSEEIDQLQENLSRVnlseedKEKLQKLTELKESLECTVDQEQKRSSAL--EKELAE--FKEVLKMTKKELNEY 1354
Cdd:TIGR00606 729 LGLAPGRQSIIDLKEKEIPEL------RNKLQKVNRDIQRLKNDIEEQETLLGTImpEEESAKvcLTDVTIMERFQMELK 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1355 ENRELNLRQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHLGKknqLLQQELLLMRTIQKKCGKLEKNKKQLEQE 1434
Cdd:TIGR00606 803 DVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRK---LIQDQQEQIQHLKSKTNELKSEKLQIGTN 879
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1435 VVNLRSHMEKNMVEHSQAQQYAREVEERARQDLVEKLkqvnlFLQAQAASQESLEQLRENSNASVRSQMELRIKDLESQL 1514
Cdd:TIGR00606 880 LQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLET-----FLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIH 954
|
810 820 830 840
....*....|....*....|....*....|....*....|....
gi 568941650 1515 YRMKAQEDFDKIELEKYKQLYQEEFRARKSLSSKLNKTSEKLEE 1558
Cdd:TIGR00606 955 GYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINE 998
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
25-212 |
2.51e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 62.00 E-value: 2.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 25 CVGFGRESASGSHVPRYHIHDK-DMGKIHKAASVGDVAKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVER 103
Cdd:PHA02876 121 CIHILKEAISGNDIHYDKINESiEYMKLIKERIQQDELLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSY 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 104 ---------------KCEIDARDSESSTALI--------------KAVQCQEEECAAILLDHGADPNVMDSSGNTALHYA 154
Cdd:PHA02876 201 gadvniialddlsvlECAVDSKNIDTIKAIIdnrsninkndlsllKAIRNEDLETSLLLYDAGFSVNSIDDCKNTPLHHA 280
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 155 VYSENTS-MAAKLLAHNANIEAKNKDDLTPMLLAVKEN-KQHIVEFLVKKKASIHAVDQL 212
Cdd:PHA02876 281 SQAPSLSrLVPKLLERGADVNAKNIKGETPLYLMAKNGyDTENIRTLIMLGADVNAADRL 340
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
41-210 |
2.91e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 61.43 E-value: 2.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 41 YHIHDKDMGKIHKAASVGdvAKVQHILILGKSGVNDRDK-KDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALI 119
Cdd:PHA02878 129 QTIDLVYIDKKSKDDIIE--AEITKLLLSYGADINMKDRhKGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLH 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 120 KAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAV-YSENTSMAAKLLAHNANIEAKNK-DDLTPMLLAVKEnkQHIVE 197
Cdd:PHA02878 207 HAVKHYNKPIVHILLENGASTDARDKCGNTPLHISVgYCKDYDILKLLLEHGVDVNAKSYiLGLTALHSSIKS--ERKLK 284
|
170
....*....|...
gi 568941650 198 FLVKKKASIHAVD 210
Cdd:PHA02878 285 LLLEYGADINSLN 297
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
908-1558 |
3.51e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 61.57 E-value: 3.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 908 IKSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTK---TIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVe 984
Cdd:TIGR04523 27 IANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKdeeKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDL- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 985 sfrSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDEL 1064
Cdd:TIGR04523 106 ---SKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEK 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1065 REKtlalkhaQRDLSQTQCQMKEVEHMFQDEQGKVSKfmgkQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNI 1144
Cdd:TIGR04523 183 LNI-------QKNIDKIKNKLLKLELLLSNLKKKIQK----NKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNT 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1145 QDQFQDVLTrfqaESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKkqsmseaslevssr 1224
Cdd:TIGR04523 252 QTQLNQLKD----EQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELK-------------- 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1225 yrsnleEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENlsrvnlSEE 1304
Cdd:TIGR04523 314 ------SELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKE------NQS 381
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1305 DKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNnhLEMDIPV-STLIKKI 1383
Cdd:TIGR04523 382 YKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKD--LTNQDSVkELIIKNL 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1384 DDLTAKLETASSKCLHLGKKNQLlqqelllmrtiqkkcgKLEKNKKQLEQEVVNLRSHMEKNmvehsqaqqyareveera 1463
Cdd:TIGR04523 460 DNTRESLETQLKVLSRSINKIKQ----------------NLEQKQKELKSKEKELKKLNEEK------------------ 505
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1464 rQDLVEKLKQVNlflQAQAASQESLEQLRensnaSVRSQMELRIKDLESQLYRMKaqEDFDKIELEKYKQLYQEEFRARK 1543
Cdd:TIGR04523 506 -KELEEKVKDLT---KKISSLKEKIEKLE-----SEKKEKESKISDLEDELNKDD--FELKKENLEKEIDEKNKEIEELK 574
|
650
....*....|....*
gi 568941650 1544 SLSSKLNKTSEKLEE 1558
Cdd:TIGR04523 575 QTQKSLKKKQEEKQE 589
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
745-1324 |
6.02e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 61.21 E-value: 6.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 745 SETEEVKSRLEHEKV-GWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLrrkgeqcqSEVEARQQleaslrtlemELKT 823
Cdd:PRK02224 194 AQIEEKEEKDLHERLnGLESELAELDEEIERYEEQREQARETRDEADEVL--------EEHEERRE----------ELET 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 824 VKSHLNQVLEERNETQRQlsREQNARmlqdgilashlckqkeiemtqkkmtsEVSVSHEKEKDLLHKNQRLQDEVAVLRL 903
Cdd:PRK02224 256 LEAEIEDLRETIAETERE--REELAE--------------------------EVRDLRERLEELEEERDDLLAEAGLDDA 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 904 EMDTIKSHNQEKEKRyledikiANEKNDNLQRmVKLNEETFTKTIFQYTGQLNSLKAENTmlsskldnEKQNK-ERLETD 982
Cdd:PRK02224 308 DAEAVEARREELEDR-------DEELRDRLEE-CRVAAQAHNEEAESLREDADDLEERAE--------ELREEaAELESE 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 983 VESFRSRLASALHDHAEIQTAKRDLEIAFQRARDewfrvkdkmnfDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKD 1062
Cdd:PRK02224 372 LEEAREAVEDRREEIEELEEEIEELRERFGDAPV-----------DLGNAEDFLEELREERDELREREAELEATLRTARE 440
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1063 ELREktlalkhAQRDLSQTQC-----QMKEVEHMFQDEQGKVskfmgKQESIEERLAQLQSENTLLRQQLDDA--ANKAE 1135
Cdd:PRK02224 441 RVEE-------AEALLEAGKCpecgqPVEGSPHVETIEEDRE-----RVEELEAELEDLEEEVEEVEERLERAedLVEAE 508
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1136 SKDKTIVNIQDQFQDVLTRFQAESQRHSLRLE---DRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELAdTLKKQ 1212
Cdd:PRK02224 509 DRIERLEERREDLEELIAERRETIEEKRERAEelrERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLA-ELKER 587
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1213 SMSEASLEVSSRYRSNLEEEARDLKKKLGQL-------RSQLQEARDQHREAvhHAEKMEDHLQKLELEKSKFEITIKKQ 1285
Cdd:PRK02224 588 IESLERIRTLLAAIADAEDEIERLREKREALaelnderRERLAEKRERKREL--EAEFDEARIEEAREDKERAEEYLEQV 665
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 568941650 1286 SEEIDQLQEN----LSRVNLSEEDKEKLQKLTELKESLECTVD 1324
Cdd:PRK02224 666 EEKLDELREErddlQAEIGAVENELEELEELRERREALENRVE 708
|
|
| PHA02878 |
PHA02878 |
ankyrin repeat protein; Provisional |
51-214 |
8.15e-09 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 59.89 E-value: 8.15e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 51 IHKAASVGDVAKVQHILILGKSgVNDRDKKDRTALHLACAY----GHPEVVTLLVERKCE-------------------- 106
Cdd:PHA02878 41 LHQAVEARNLDVVKSLLTRGHN-VNQPDHRDLTPLHIICKEpnklGMKEMIRSINKCSVFytlvaikdafnnrnveifki 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 107 --IDARDSESSTALIKAVQCQ-----EEECAAILLDHGADPNVMD-SSGNTALHYAVYSENTSMAAKLLAHNANIEAKNK 178
Cdd:PHA02878 120 ilTNRYKNIQTIDLVYIDKKSkddiiEAEITKLLLSYGADINMKDrHKGNTALHYATENKDQRLTELLLSYGANVNIPDK 199
|
170 180 190
....*....|....*....|....*....|....*.
gi 568941650 179 DDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLGS 214
Cdd:PHA02878 200 TNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGN 235
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
914-1361 |
9.05e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 60.46 E-value: 9.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 914 EKEKRYLEDIKIANEkndNLQRMVKLNEETFTKTIfqytGQLNSLKAENTMLSSKLDNEKQNKERLEtdveSFRSRLASA 993
Cdd:PRK03918 175 KRRIERLEKFIKRTE---NIEELIKEKEKELEEVL----REINEISSELPELREELEKLEKEVKELE----ELKEEIEEL 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 994 LHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVlsQQLSKTERKLNSLEIEFhhtKDELREKTLALKH 1073
Cdd:PRK03918 244 EKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL--KEKAEEYIKLSEFYEEY---LDELREIEKRLSR 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1074 AQRDLSQTQCQMKEVEhmfqDEQGKVSKFMGKQESIEERLAQLQSENTLL---RQQLDDAAN-KAESKDKTIVNIQDQFQ 1149
Cdd:PRK03918 319 LEEEINGIEERIKELE----EKEERLEELKKKLKELEKRLEELEERHELYeeaKAKKEELERlKKRLTGLTPEKLEKELE 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1150 DvltrfqaesqrhslrLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQ----------QELADTLKKQSMSEASL 1219
Cdd:PRK03918 395 E---------------LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgRELTEEHRKELLEEYTA 459
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1220 EVSsryrsNLEEEARDLKKKLGQLRSQLQEardqhreavhhaekmedhLQKLELEKSKFeITIKKQSEEIDQLQENLSRV 1299
Cdd:PRK03918 460 ELK-----RIEKELKEIEEKERKLRKELRE------------------LEKVLKKESEL-IKLKELAEQLKELEEKLKKY 515
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568941650 1300 NLS--EEDKEKLQKLTELKESLEC---TVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNL 1361
Cdd:PRK03918 516 NLEelEKKAEEYEKLKEKLIKLKGeikSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEEL 582
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
713-1317 |
9.20e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 60.46 E-value: 9.20e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 713 KRLIELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQ 792
Cdd:PRK03918 171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 793 LRRKGEqcqsevearqqLEASLRTLEMELKTVKSHLnQVLEERNETQRQLSREQNARMLQDGILASHLCKQKEIEMTQKK 872
Cdd:PRK03918 251 EGSKRK-----------LEEKIRELEERIEELKKEI-EELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 873 MTSEVSVSHEKEKDLLHKNQRLQDevavlrlemdtIKSHNQEKEKRYLEdikianekndnLQRMVKLNEEtftktIFQYT 952
Cdd:PRK03918 319 LEEEINGIEERIKELEEKEERLEE-----------LKKKLKELEKRLEE-----------LEERHELYEE-----AKAKK 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 953 GQLNSLKAENTMLS-----SKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQR--------ARDEWF 1019
Cdd:PRK03918 372 EELERLKKRLTGLTpekleKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelTEEHRK 451
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1020 RVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLA--LKHAQRDLSQTQCQ-MKEVEHMFQDEQ 1096
Cdd:PRK03918 452 ELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAeqLKELEEKLKKYNLEeLEKKAEEYEKLK 531
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1097 GKVSKFMGKQESIE---ERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQ-DQFQDVLTRFQAESQRHSLRLEDRNQE 1172
Cdd:PRK03918 532 EKLIKLKGEIKSLKkelEKLEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPFYNEYLELKDAE 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1173 lvSECSHLRERLcqyenEKAEREVVvrQLQQELADTLKKQSMSEASLEVSSRYRSnlEEEARDLKKKLGQLRSQLQEARD 1252
Cdd:PRK03918 612 --KELEREEKEL-----KKLEEELD--KAFEELAETEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRA 680
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568941650 1253 QHREAVHHAEKMEDHLQKLELEKSKfeitIKKQSEEIDQLQENLSRVnlsEEDKEKLQKL-TELKE 1317
Cdd:PRK03918 681 ELEELEKRREEIKKTLEKLKEELEE----REKAKKELEKLEKALERV---EELREKVKKYkALLKE 739
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
761-1569 |
1.45e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 60.06 E-value: 1.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 761 WEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQR 840
Cdd:TIGR00606 243 YENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELV 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 841 QLSREQNaRMLQDGILASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDT---IKSHNQEKEK 917
Cdd:TIGR00606 323 DCQRELE-KLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSerqIKNFHTLVIE 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 918 RYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTGQLNSLKAENTMLSSKLDN-----------EKQNKERLETDVESF 986
Cdd:TIGR00606 402 RQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEElkfvikelqqlEGSSDRILELDQELR 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 987 RSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERK----------------- 1049
Cdd:TIGR00606 482 KAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKmdkdeqirkiksrhsde 561
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1050 LNSLEIEFHHTK---DELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQ------LQSEN 1120
Cdd:TIGR00606 562 LTSLLGYFPNKKqleDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDvcgsqdEESDL 641
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1121 TLLRQQLDDAAnKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQ 1200
Cdd:TIGR00606 642 ERLKEEIEKSS-KQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKK 720
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1201 LQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHL------QKLELE 1274
Cdd:TIGR00606 721 KEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLtdvtimERFQME 800
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1275 KSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLEctvdqeqkrssALEKELAEFKEVLKMTKKELNEY 1354
Cdd:TIGR00606 801 LKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIE-----------LNRKLIQDQQEQIQHLKSKTNEL 869
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1355 ENRELNLRQDIKNNHlEMDIPVSTLIKKIDDLTAKLETASSKCLHLgkKNQLLQQELLLMRTIQKKcgklEKNKKQLEQE 1434
Cdd:TIGR00606 870 KSEKLQIGTNLQRRQ-QFEEQLVELSTEVQSLIREIKDAKEQDSPL--ETFLEKDQQEKEELISSK----ETSNKKAQDK 942
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1435 VVNLRSHMEKNMVEHSQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQmELRIKDLESQL 1514
Cdd:TIGR00606 943 VNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ-KIQERWLQDNL 1021
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*...
gi 568941650 1515 YRMKAQEDFDKIELEK---YKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQ 1569
Cdd:TIGR00606 1022 TLRKRENELKEVEEELkqhLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKG 1079
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
83-207 |
1.57e-08 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 59.26 E-value: 1.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 83 TALHLACAYGHPEVVTLLVERKCE-IDARD-----SESSTALIK--------AVQCQEEECAAILLDHGADPNVMDSSGN 148
Cdd:cd22192 91 TALHIAVVNQNLNLVRELIARGADvVSPRAtgtffRPGPKNLIYygehplsfAACVGNEEIVRLLIEHGADIRAQDSLGN 170
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941650 149 TALHYAVYSENTSMAAK----LLAHNANIEA------KNKDDLTPMLLAVKENKQHIVEFLVKKKASIH 207
Cdd:cd22192 171 TVLHILVLQPNKTFACQmydlILSYDKEDDLqpldlvPNNQGLTPFKLAAKEGNIVMFQHLVQKRRHIQ 239
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
115-167 |
2.02e-08 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 51.89 E-value: 2.02e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 568941650 115 STALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLL 167
Cdd:pfam13637 2 LTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
741-1368 |
2.74e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 58.96 E-value: 2.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 741 QKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEK--TSEQLRRKGEQCQSEVEARQQLE---ASLR 815
Cdd:pfam05483 103 QKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENnaTRHLCNLLKETCARSAEKTKKYEyerEETR 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 816 TLEMELKTVKSHLNQVLEERNETQRQLSREQNARMLQDGILASHLCK--QKEIEMTQKKMTSEVSVSHEKE---KDLLHK 890
Cdd:pfam05483 183 QVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEeyKKEINDKEKQVSLLLIQITEKEnkmKDLTFL 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 891 NQRLQDEVAVL----RLEMDTIKSHNQEKE--KRYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTGQ---------- 954
Cdd:pfam05483 263 LEESRDKANQLeektKLQDENLKELIEKKDhlTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEkeaqmeelnk 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 955 --------LNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQrardewfRVKDKMN 1026
Cdd:pfam05483 343 akaahsfvVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELE-------ELKKILA 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1027 FDMSNLRDNNEV--LSQQLSKTERKLNSL----EIEFHHTKDELREKTLALKHAQRdlsqtqcQMKEVEHMFQDEQGKVS 1100
Cdd:pfam05483 416 EDEKLLDEKKQFekIAEELKGKEQELIFLlqarEKEIHDLEIQLTAIKTSEEHYLK-------EVEDLKTELEKEKLKNI 488
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1101 KFMGKQEsieerlaQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQA-ESQRHSLR--LEDRNQELVSEC 1177
Cdd:pfam05483 489 ELTAHCD-------KLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENlEEKEMNLRdeLESVREEFIQKG 561
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1178 SHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKK--------------KLGQL 1243
Cdd:pfam05483 562 DEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKkgsaenkqlnayeiKVNKL 641
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1244 RSQLQEARDQHREAVHHAEK--------MEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSR-VNLSEEDKEKLQKLTE 1314
Cdd:pfam05483 642 ELELASAKQKFEEIIDNYQKeiedkkisEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEmVALMEKHKHQYDKIIE 721
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 568941650 1315 LKES-LECTVDQEQKRSS---ALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNN 1368
Cdd:pfam05483 722 ERDSeLGLYKNKEQEQSSakaALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKEN 779
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1007-1393 |
7.71e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.08 E-value: 7.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1007 LEIAFQRARDEWFRVKDKmnfdmsnlrdNNEVLSQQLSKTERKLNSLEIEfhhtKDELREKTLALKHAQRDLSQTQCQMK 1086
Cdd:COG4717 47 LLERLEKEADELFKPQGR----------KPELNLKELKELEEELKEAEEK----EEEYAELQEELEELEEELEELEAELE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1087 EVEHMFQ--DEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLD---DAANKAESKDKTIVNIQDQFQDVLTRFQAESQR 1161
Cdd:COG4717 113 ELREELEklEKLLQLLPLYQELEALEAELAELPERLEELEERLEelrELEEELEELEAELAELQEELEELLEQLSLATEE 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1162 HSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEAS----------------------- 1218
Cdd:COG4717 193 ELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARlllliaaallallglggsllsli 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1219 ---------------LEVSSRYRSNLEEEARDLKKKLGQLRSQLQEAR--------------------------DQHREA 1257
Cdd:COG4717 273 ltiagvlflvlgllaLLFLLLAREKASLGKEAEELQALPALEELEEEEleellaalglppdlspeellelldriEELQEL 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1258 VHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSS--ALEK 1335
Cdd:COG4717 353 LREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDeeELEE 432
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 568941650 1336 ELAEFKEVLKMTKKELNEYENRELNLRQDIKnnHLEMDIPVSTLIKKIDDLTAKLETA 1393
Cdd:COG4717 433 ELEELEEELEELEEELEELREELAELEAELE--QLEEDGELAELLQELEELKAELREL 488
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
825-1471 |
1.13e-07 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 57.05 E-value: 1.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 825 KSHLNQVLEERN----ETQRQLSREQNARMLQDGILASHL----CKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQD 896
Cdd:pfam15921 73 KEHIERVLEEYShqvkDLQRRLNESNELHEKQKFYLRQSVidlqTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVH 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 897 EVAVLR-LEMDTIKSHNQEKEK----------------RYLEDIKIANEK----NDNLQRM---------VKLNEETFTK 946
Cdd:pfam15921 153 ELEAAKcLKEDMLEDSNTQIEQlrkmmlshegvlqeirSILVDFEEASGKkiyeHDSMSTMhfrslgsaiSKILRELDTE 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 947 T------IFQYTGQLNSLKAENT-----MLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTakrDLEIAFQRAR 1015
Cdd:pfam15921 233 IsylkgrIFPVEDQLEALKSESQnkielLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQS---QLEIIQEQAR 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1016 DE---WFRVKDKMNFDMSNLR-----------DNNEVLSQQL---------SKTER------------KLNSLEIEFHHT 1060
Cdd:pfam15921 310 NQnsmYMRQLSDLESTVSQLRselreakrmyeDKIEELEKQLvlanselteARTERdqfsqesgnlddQLQKLLADLHKR 389
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1061 KDELR-EK-------------TLALKHAQRDLSQTQCQMKEVEHMFQ----DEQGKVSKFM----GKQESIEE---RLAQ 1115
Cdd:pfam15921 390 EKELSlEKeqnkrlwdrdtgnSITIDHLRRELDDRNMEVQRLEALLKamksECQGQMERQMaaiqGKNESLEKvssLTAQ 469
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1116 LQSENTLLRQQLDDAANKA---ESKDKTIVNIQDQFQDVLTRFQAES-------QRHSLRLEDRnQELVSECSHLRERLC 1185
Cdd:pfam15921 470 LESTKEMLRKVVEELTAKKmtlESSERTVSDLTASLQEKERAIEATNaeitklrSRVDLKLQEL-QHLKNEGDHLRNVQT 548
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1186 QYENEK---AEREVVVRQLQQELADTLKKQSMseaslevSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAE 1262
Cdd:pfam15921 549 ECEALKlqmAEKDKVIEILRQQIENMTQLVGQ-------HGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIR 621
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1263 KMEDHLQKLELEKSKFeitIKKQSEEIDQLQE-NLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFK 1341
Cdd:pfam15921 622 ELEARVSDLELEKVKL---VNAGSERLRAVKDiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLK 698
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1342 EVLKMTKKELNEYENRELNLRQdiKNNH-----LEMDIPVSTLIKKIDDLTAKLE------TASSKCLHLGK--KNQLLQ 1408
Cdd:pfam15921 699 MQLKSAQSELEQTRNTLKSMEG--SDGHamkvaMGMQKQITAKRGQIDALQSKIQfleeamTNANKEKHFLKeeKNKLSQ 776
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568941650 1409 QELLLMRTIQKKCGKLE---KNKKQLEQEVVNLRSHMEKNMVEHSQAQQ-YAREVEERARQDLVEKL 1471
Cdd:pfam15921 777 ELSTVATEKNKMAGELEvlrSQERRLKEKVANMEVALDKASLQFAECQDiIQRQEQESVRLKLQHTL 843
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
907-1573 |
1.15e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 56.65 E-value: 1.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 907 TIKSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTGQLNSLKAENT------MLSSKLDNEKQNKERLE 980
Cdd:pfam05483 96 SIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNAtrhlcnLLKETCARSAEKTKKYE 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 981 TDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEW-FRVKDkmnfDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHH 1059
Cdd:pfam05483 176 YEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMhFKLKE----DHEKIQHLEEEYKKEINDKEKQVSLLLIQITE 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1060 TKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAAnkaeskdK 1139
Cdd:pfam05483 252 KENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIAT-------K 324
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1140 TIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQEladtlkkqsmsEASL 1219
Cdd:pfam05483 325 TICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKK-----------SSEL 393
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1220 EVSSRYRSNLEEEARDLKKKLG----------QLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEI 1289
Cdd:pfam05483 394 EEMTKFKNNKEVELEELKKILAedeklldekkQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEV 473
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1290 DQLQENLsrvnlsEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNH 1369
Cdd:pfam05483 474 EDLKTEL------EKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLR 547
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1370 LEMDIPVSTLIKKIDDLTAKL----ETASSKCLHLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRshmEKN 1445
Cdd:pfam05483 548 DELESVREEFIQKGDEVKCKLdkseENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALK---KKG 624
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1446 MVEHSQAQQYAREVE------ERARQDLVEKLKQVNLFLQAQAASQESL----EQLRENSNASVRSQMEL------RIKD 1509
Cdd:pfam05483 625 SAENKQLNAYEIKVNklelelASAKQKFEEIIDNYQKEIEDKKISEEKLleevEKAKAIADEAVKLQKEIdkrcqhKIAE 704
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1510 LESQLYRMKAQedFDKI------ELEKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQNRSL 1573
Cdd:pfam05483 705 MVALMEKHKHQ--YDKIieerdsELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKL 772
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
74-121 |
1.51e-07 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 49.65 E-value: 1.51e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 568941650 74 VNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKA 121
Cdd:pfam13857 9 LNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1168-1367 |
1.58e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.54 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1168 DRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQL 1247
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1248 QEARDQHREAVHHAEKMEDHLQKLELEKSK-----------FEITIKKQSEEIDQLQENLsrvnlsEEDKEKLQKLTELK 1316
Cdd:COG4942 100 EAQKEELAELLRALYRLGRQPPLALLLSPEdfldavrrlqyLKYLAPARREQAEELRADL------AELAALRAELEAER 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 568941650 1317 ESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKN 1367
Cdd:COG4942 174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
656-1249 |
1.67e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.48 E-value: 1.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 656 AAVDNLDDFTESSETASEDHELQGPDSESILCAIEHLRleckdtASLLKIRDAVYSYKRLIELKRSHCELLTGKLKRMEN 735
Cdd:COG1196 229 LLLLKLRELEAELEELEAELEELEAELEELEAELAELE------AELEELRLELEELELELEEAQAEEYELLAELARLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 736 KYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLR 815
Cdd:COG1196 303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 816 TLEMELKTVKSHLNQVLEERNETQRQLSREQNARmlqdgilASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQ 895
Cdd:COG1196 383 ELAEELLEALRAAAELAAQLEELEEAEEALLERL-------ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 896 DEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKN---DNLQRMVKLNEEtftktiFQYTGQLNSLKAENTMLSSKLDNE 972
Cdd:COG1196 456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAarlLLLLEAEADYEG------FLEGVKAALLLAGLRGLAGAVAVL 529
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 973 KQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNfdmsNLRDNNEVLSQQLSKTERKLNS 1052
Cdd:COG1196 530 IGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR----ARAALAAALARGAIGAAVDLVA 605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1053 LEIEFHHTKDELREKTLALK-HAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAA 1131
Cdd:COG1196 606 SDLREADARYYVLGDTLLGRtLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1132 NKAEskdktivniqdqfqdvltrfQAESQRHSLRLEDRNQELvsecsHLRERLCQYENEKAEREVVVRQLQQELADTLKK 1211
Cdd:COG1196 686 ERLA--------------------EEELELEEALLAEEEEER-----ELAEAEEERLEEELEEEALEEQLEAEREELLEE 740
|
570 580 590
....*....|....*....|....*....|....*...
gi 568941650 1212 QSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQE 1249
Cdd:COG1196 741 LLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
734-1373 |
2.15e-07 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 56.21 E-value: 2.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 734 ENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSEQLRRKG--EQCQSEVEARQQLE 811
Cdd:TIGR00606 318 ERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGfeRGPFSERQIKNFHT 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 812 ASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQNARMLQDGILASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKN 891
Cdd:TIGR00606 398 LVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELD 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 892 QRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIK--IANEKNDNLQRMVKLNEETFTKTI-------------------FQ 950
Cdd:TIGR00606 478 QELRKAERELSKAEKNSLTETLKKEVKSLQNEKadLDRKLRKLDQEMEQLNHHTTTRTQmemltkdkmdkdeqirkikSR 557
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 951 YTGQLNSLKAE---NTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNF 1027
Cdd:TIGR00606 558 HSDELTSLLGYfpnKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE 637
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1028 --DMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDelrEKTLALKHAQRDLsQTQcqmKEVEHMFQDEQGKVSKFMGK 1105
Cdd:TIGR00606 638 esDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTD---ENQSCCPVCQRVF-QTE---AELQEFISDLQSKLRLAPDK 710
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1106 QESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQ--------AESQRHSLRLEDRNQELVSEC 1177
Cdd:TIGR00606 711 LKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQrlkndieeQETLLGTIMPEEESAKVCLTD 790
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1178 SHLRERLcQYENEKAEREV--------------VVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQL 1243
Cdd:TIGR00606 791 VTIMERF-QMELKDVERKIaqqaaklqgsdldrTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNEL 869
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1244 RSQlqeaRDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEI--------DQLQENLSRVNLSEEDKEKLQ-KLTE 1314
Cdd:TIGR00606 870 KSE----KLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDspletfleKDQQEKEELISSKETSNKKAQdKVND 945
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568941650 1315 LKESlectVDQEQKRSSALEKELAEFKEVLKMTKK--------ELNEYENRELNLRQDIKNNHLEMD 1373
Cdd:TIGR00606 946 IKEK----VKNIHGYMKDIENKIQDGKDDYLKQKEtelntvnaQLEECEKHQEKINEDMRLMRQDID 1008
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
1107-1579 |
2.90e-07 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 55.57 E-value: 2.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1107 ESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQdqfqdvLTRFQAESQRHSLR-----LEDRNQELVSECSHLR 1181
Cdd:pfam01576 85 EEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQ------LEKVTTEAKIKKLEedillLEDQNSKLSKERKLLE 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1182 ERLCQYENEKAEREVVVRQLQQ----------ELADTLKKQSMSEASLEVSSRyrsNLEEEARDLKKKLGQLRSQLQEAR 1251
Cdd:pfam01576 159 ERISEFTSNLAEEEEKAKSLSKlknkheamisDLEERLKKEEKGRQELEKAKR---KLEGESTDLQEQIAELQAQIAELR 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1252 DQHREavhHAEKMEDHLQKLELEKSKFEITIKKQSE---EIDQLQENLSRVNLSEEDKEKLQK---------LTELKESL 1319
Cdd:pfam01576 236 AQLAK---KEEELQAALARLEEETAQKNNALKKIREleaQISELQEDLESERAARNKAEKQRRdlgeelealKTELEDTL 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1320 ECTVDQEQKRSSAlEKELAEFKEVLKmtkKELNEYENRELNLRQdiKNNhlemdipvstliKKIDDLTAKLETASSKCLH 1399
Cdd:pfam01576 313 DTTAAQQELRSKR-EQEVTELKKALE---EETRSHEAQLQEMRQ--KHT------------QALEELTEQLEQAKRNKAN 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1400 LGKKN----QLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLrshmeknMVEHSQAqqyareveERARQDLVEKLKQVN 1475
Cdd:pfam01576 375 LEKAKqaleSENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-------QARLSES--------ERQRAELAEKLSKLQ 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1476 LFLQAQAASQESLEqlrensNASVRSQMELriKDLESQLYrmKAQEdfdkielekykqLYQEEFRARKSLSSKLNKTSEK 1555
Cdd:pfam01576 440 SELESVSSLLNEAE------GKNIKLSKDV--SSLESQLQ--DTQE------------LLQEETRQKLNLSTRLRQLEDE 497
|
490 500
....*....|....*....|....
gi 568941650 1556 LEEASSKLLLEEQQNRSLLSTLST 1579
Cdd:pfam01576 498 RNSLQEQLEEEEEAKRNVERQLST 521
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
737-1370 |
3.23e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 55.31 E-value: 3.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 737 YKGLQKEMSETEEVKSRLEhekvgweqELCRLRFALKQEEEKRRSADQLSEK-TSEQLRRKGEQCQSEVEarqQLEASLR 815
Cdd:COG4913 237 LERAHEALEDAREQIELLE--------PIRELAERYAAARERLAELEYLRAAlRLWFAQRRLELLEAELE---ELRAELA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 816 TLEMELKTVKSHLNQVLEERNETQRQLSReqnarmlQDGILASHLckQKEIEMTQkkmtsevsvshEKEKDLLHKNQRLQ 895
Cdd:COG4913 306 RLEAELERLEARLDALREELDELEAQIRG-------NGGDRLEQL--EREIERLE-----------RELEERERRRARLE 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 896 DEVAVLRLEMDTIkshnqekEKRYLEDIKIANEKNDNLQRMVKLNEETFTKTIfqytGQLNSLKAENTMLSSKLDNEKQN 975
Cdd:COG4913 366 ALLAALGLPLPAS-------AEEFAALRAEAAALLEALEEELEALEEALAEAE----AALRDLRRELRELEAEIASLERR 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 976 KERLETDVESFRSRLASAL-----------------HDHAEIQTA--------KRDL---EIAFQRARdEWF-RVKDKMN 1026
Cdd:COG4913 435 KSNIPARLLALRDALAEALgldeaelpfvgelievrPEEERWRGAiervlggfALTLlvpPEHYAAAL-RWVnRLHLRGR 513
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1027 FDMSNLRDNNEvlSQQLSKTE-----RKLNSLEIEFHHT-KDELREKTL--------ALKHAQRDLSQTqCQMKEVEHMF 1092
Cdd:COG4913 514 LVYERVRTGLP--DPERPRLDpdslaGKLDFKPHPFRAWlEAELGRRFDyvcvdspeELRRHPRAITRA-GQVKGNGTRH 590
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1093 Q-DEQGKVSK--FMGkqESIEERLAQLQSENTLLRQQLDDAANKAESkdktivnIQDQFQDVLTRFQAESQRHSLRLEDR 1169
Cdd:COG4913 591 EkDDRRRIRSryVLG--FDNRAKLAALEAELAELEEELAEAEERLEA-------LEAELDALQERREALQRLAEYSWDEI 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1170 N-QELVSECSHLRERLCQYENEKAErevvVRQLQQELaDTLKKQsmseaslevssryRSNLEEEARDLKKKLGQLRSQLQ 1248
Cdd:COG4913 662 DvASAEREIAELEAELERLDASSDD----LAALEEQL-EELEAE-------------LEELEEELDELKGEIGRLEKELE 723
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1249 EARDQHREA---VHHAEKMEDHLQKLELEKsKFEITIKKQSEeiDQLQENLSrvnlseedkEKLQKLTELKESLEctvdq 1325
Cdd:COG4913 724 QAEEELDELqdrLEAAEDLARLELRALLEE-RFAAALGDAVE--RELRENLE---------ERIDALRARLNRAE----- 786
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 568941650 1326 eqkrsSALEKELAEFKEVLKMTKKEL-------NEYenreLNLRQDIKNNHL 1370
Cdd:COG4913 787 -----EELERAMRAFNREWPAETADLdadleslPEY----LALLDRLEEDGL 829
|
|
| Ank_2 |
pfam12796 |
Ankyrin repeats (3 copies); |
151-202 |
8.06e-07 |
|
Ankyrin repeats (3 copies);
Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 48.57 E-value: 8.06e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 568941650 151 LHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKK 202
Cdd:pfam12796 1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH 52
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
130-224 |
9.32e-07 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 53.75 E-value: 9.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 130 AAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHav 209
Cdd:PTZ00322 98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRHSQCHF-- 175
|
90
....*....|....*
gi 568941650 210 dQLGSNRQMFEYDGK 224
Cdd:PTZ00322 176 -ELGANAKPDSFTGK 189
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
728-1467 |
1.02e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.99 E-value: 1.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 728 GKLKRMENKYKGLQKEMSETEEVKSRLEH----EKVGWEQELCRLRFALKQEEEKRRSADQLSEKTSE-QLRRKGEQCQS 802
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDarkaEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKaEEARKAEDAKK 1177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 803 EVEARQQLEasLRTLEmELKTVKSHLNQVLEERNETQRqlsREQNARMLQDGILASHLCKQKEIemtqkKMTSEVSVSHE 882
Cdd:PTZ00121 1178 AEAARKAEE--VRKAE-ELRKAEDARKAEAARKAEEER---KAEEARKAEDAKKAEAVKKAEEA-----KKDAEEAKKAE 1246
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 883 KEKDLLHKNQRLQDEVAVLRLEMDTIKShnqeKEKRYLEDIKIANE--KNDNLQRMVKLNEETFTKTIFQYTGQLNSLKA 960
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKA----EEARKADELKKAEEkkKADEAKKAEEKKKADEAKKKAEEAKKADEAKK 1322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 961 ENTMLSSKLDNEKQNKERLETDVESFRsrlasalhdhAEIQTAKRDLEIAFQRAR-DEWFRVKDKMNFDMSNLRDNNEVL 1039
Cdd:PTZ00121 1323 KAEEAKKKADAAKKKAEEAKKAAEAAK----------AEAEAAADEAEAAEEKAEaAEKKKEEAKKKADAAKKKAEEKKK 1392
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1040 SQQLSKTERklnsleiEFHHTKDELREKTLALKHAQrDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSE 1119
Cdd:PTZ00121 1393 ADEAKKKAE-------EDKKKADELKKAAAAKKKAD-EAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1120 NTLLRQQLDDAANKAESKDKTivniqdqfqDVLTRFQAESQRHS--LRLEDRNQELVSECSHLRERLCQYENEKAEREVV 1197
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKA---------DEAKKKAEEAKKKAdeAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK 1535
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1198 VRQLQQ----ELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLEL 1273
Cdd:PTZ00121 1536 ADEAKKaeekKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKA 1615
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1274 EKSKFEITIKKQSEEIDQLQENLSRVnlSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFK--EVLKMTKKEL 1351
Cdd:PTZ00121 1616 EEAKIKAEELKKAEEEKKKVEQLKKK--EAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKkaEEDEKKAAEA 1693
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1352 NEYENRELNLRQDIKNNHLEMdipvstlIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQL 1431
Cdd:PTZ00121 1694 LKKEAEEAKKAEELKKKEAEE-------KKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766
|
730 740 750
....*....|....*....|....*....|....*..
gi 568941650 1432 EQEVVNLRSHMEKNMVEHSQAQQYAREVE-ERARQDL 1467
Cdd:PTZ00121 1767 EKKAEEIRKEKEAVIEEELDEEDEKRRMEvDKKIKDI 1803
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
974-1572 |
1.49e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.14 E-value: 1.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 974 QNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVkDKMNFDMSNLRDNNEVLSQQLSKTERKLNSL 1053
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKLEEKIREL 264
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1054 EIEFHHTKDELREktlaLKHAQRDLSQtqcqMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAank 1133
Cdd:PRK03918 265 EERIEELKKEIEE----LEEKVKELKE----LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL--- 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1134 aESKDKTIVNIQDQFQDVLTRFQAESQRHslRLEDRNQELVSECSHLRERLCQYENEKAEREVvvrqlqqELADTLKKQS 1213
Cdd:PRK03918 334 -EEKEERLEELKKKLKELEKRLEELEERH--ELYEEAKAKKEELERLKKRLTGLTPEKLEKEL-------EELEKAKEEI 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1214 MSEASlEVSSRyRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKmeDHLQKLELEKSKFEITIKKQSEEIDQLQ 1293
Cdd:PRK03918 404 EEEIS-KITAR-IGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRK--ELLEEYTAELKRIEKELKEIEEKERKLR 479
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1294 ENLSRVNLSEEDKEKLQKLTELKESLEctvdqeqkrssALEKELAEF-KEVLKMTKKELNEYENRELNLRQDIKNnhLEM 1372
Cdd:PRK03918 480 KELRELEKVLKKESELIKLKELAEQLK-----------ELEEKLKKYnLEELEKKAEEYEKLKEKLIKLKGEIKS--LKK 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1373 DIpvstliKKIDDLTAKLetasskclhlgkknqllqqelllmRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHsqa 1452
Cdd:PRK03918 547 EL------EKLEELKKKL------------------------AELEKKLDELEEELAELLKELEELGFESVEELEER--- 593
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1453 qqyAREVEERARQDLveKLKQVNLFLQAQAASQESLEQLRENSNASVrSQMELRIKDLESQLYRMKAQedFDKIELEKYK 1532
Cdd:PRK03918 594 ---LKELEPFYNEYL--ELKDAEKELEREEKELKKLEEELDKAFEEL-AETEKRLEELRKELEELEKK--YSEEEYEELR 665
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 568941650 1533 QLYQEEFRARKSLSSKLNKTSEKLEEASSKL--LLEEQQNRS 1572
Cdd:PRK03918 666 EEYLELSRELAGLRAELEELEKRREEIKKTLekLKEELEERE 707
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
977-1557 |
1.53e-06 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 53.20 E-value: 1.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 977 ERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTerkLNSLEIE 1056
Cdd:pfam15921 81 EEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNT---VHELEAA 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1057 FHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEErlAQLQSENTLLRQQLDDAANKAES 1136
Cdd:pfam15921 158 KCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMST--MHFRSLGSAISKILRELDTEISY 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1137 KDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSE----CSHLRERLC----QYENEKAEREVVVRQLQQELADT 1208
Cdd:pfam15921 236 LKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEheveITGLTEKASsarsQANSIQSQLEIIQEQARNQNSMY 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1209 LKKQSMSEASLevsSRYRSNLEEEAR-------DLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKL--ELEKSKFE 1279
Cdd:pfam15921 316 MRQLSDLESTV---SQLRSELREAKRmyedkieELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLlaDLHKREKE 392
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1280 ITIKKQSEE------------IDQLQENLSRVNLSEEDKEKLQKL--TELKESLECTVDQEQKRSSALEK------ELAE 1339
Cdd:pfam15921 393 LSLEKEQNKrlwdrdtgnsitIDHLRRELDDRNMEVQRLEALLKAmkSECQGQMERQMAAIQGKNESLEKvssltaQLES 472
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1340 FKEVLKMTKKELN----EYENRELNLrQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHLgkknqllQQELLLMR 1415
Cdd:pfam15921 473 TKEMLRKVVEELTakkmTLESSERTV-SDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHL-------KNEGDHLR 544
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1416 TIQKKCGKLEKNKKQLEQEVVNLRSHMEkNMVEhsQAQQYAREveerARQDLVEKlKQVNLFLQAQAASQESLEQLRENS 1495
Cdd:pfam15921 545 NVQTECEALKLQMAEKDKVIEILRQQIE-NMTQ--LVGQHGRT----AGAMQVEK-AQLEKEINDRRLELQEFKILKDKK 616
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568941650 1496 NASVRsQMELRIKDLESQLYRMKAQEDFDKIELEKYKQLYQEEFRARKSLSSKLNKTSEKLE 1557
Cdd:pfam15921 617 DAKIR-ELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYE 677
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1140-1361 |
1.61e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.38 E-value: 1.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1140 TIVNIQDQFQDvLTRFQ-----AESQRHSLR-LEDRNQELVsecsHLRERLCQYENEKAEREVVVRQLQQELADtlKKQS 1213
Cdd:COG4913 226 AADALVEHFDD-LERAHealedAREQIELLEpIRELAERYA----AARERLAELEYLRAALRLWFAQRRLELLE--AELE 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1214 MSEASLEvssryrsNLEEEARDLKKKLGQLRSQLQEARDQHREAVHhaekmeDHLQKLELEKSKFEITIKKQSEEIDQLQ 1293
Cdd:COG4913 299 ELRAELA-------RLEAELERLEARLDALREELDELEAQIRGNGG------DRLEQLEREIERLERELEERERRRARLE 365
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568941650 1294 ENLSRVNLSEED-----KEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNL 1361
Cdd:COG4913 366 ALLAALGLPLPAsaeefAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNI 438
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
133-187 |
2.11e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 46.19 E-value: 2.11e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 568941650 133 LLDHG-ADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLA 187
Cdd:pfam13857 1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
926-1563 |
2.35e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 52.66 E-value: 2.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 926 ANEKNDNLQRMVKLNEETFTKTIFQYTGQLNSLKAENTmlsskldneKQNKERLE--TDVESFRSRLASALHDHAEIQTA 1003
Cdd:TIGR00618 125 KSETEEVIHDLLKLDYKTFTRVVLLPQGEFAQFLKAKS---------KEKKELLMnlFPLDQYTQLALMEFAKKKSLHGK 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1004 KRDLEIAFQrardewfRVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEI--EFHHTKDELREKTL----ALKHAQRD 1077
Cdd:TIGR00618 196 AELLTLRSQ-------LLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQshAYLTQKREAQEEQLkkqqLLKQLRAR 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1078 LSQTQCQMKEVEHMFQ--DEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLddaaNKAESKDKTIVNIQDQFQDVLTRF 1155
Cdd:TIGR00618 269 IEELRAQEAVLEETQEriNRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKM----RSRAKLLMKRAAHVKQQSSIEEQR 344
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1156 QAESQRHslRLEDRNQELVSECSHLRERLCQyenEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEA-- 1233
Cdd:TIGR00618 345 RLLQTLH--SQEIHIRDAHEVATSIREISCQ---QHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSaf 419
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1234 RDLKKKLGQLRSQLQEardQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQeNLSRVNLSEEDKEKL--QK 1311
Cdd:TIGR00618 420 RDLQGQLAHAKKQQEL---QQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQ-TKEQIHLQETRKKAVvlAR 495
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1312 LTELKEsLECTVDQE-----------------QKRSSALEKELAEFKEVLKMTKKELNEyenrELNLRQDIKNNHLEMDI 1374
Cdd:TIGR00618 496 LLELQE-EPCPLCGScihpnparqdidnpgplTRRMQRGEQTYAQLETSEEDVYHQLTS----ERKQRASLKEQMQEIQQ 570
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1375 PVSTLIKKIDDLTA---KLETASSKCLHLGKKNQLLQQelllmrtiqKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQ 1451
Cdd:TIGR00618 571 SFSILTQCDNRSKEdipNLQNITVRLQDLTEKLSEAED---------MLACEQHALLRKLQPEQDLQDVRLHLQQCSQEL 641
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1452 AQQ---YAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQMElrikDLESQLYRMKAQEDfdkiEL 1528
Cdd:TIGR00618 642 ALKltaLHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKE----MLAQCQTLLRELET----HI 713
|
650 660 670
....*....|....*....|....*....|....*
gi 568941650 1529 EKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKL 1563
Cdd:TIGR00618 714 EEYDREFNEIENASSSLGSDLAAREDALNQSLKEL 748
|
|
| trp |
TIGR00870 |
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ... |
74-203 |
2.46e-06 |
|
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273311 [Multi-domain] Cd Length: 743 Bit Score: 52.39 E-value: 2.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 74 VNDRDK----KDRTALHLACAYGHPEVVTLLVERKCEIDAR----------------DSESSTALIKAVQcqEEECAAIL 133
Cdd:TIGR00870 117 ANDQYTseftPGITALHLAAHRQNYEIVKLLLERGASVPARacgdffvksqgvdsfyHGESPLNAAACLG--SPSIVALL 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 134 LDHGADPNVMDSSGNTALHYAV-----YSENTSM-------AAKLLAHNANIEA----KNKDDLTPMLLAVKENK----Q 193
Cdd:TIGR00870 195 SEDPADILTADSLGNTLLHLLVmenefKAEYEELscqmynfALSLLDKLRDSKEleviLNHQGLTPLKLAAKEGRivlfR 274
|
170
....*....|
gi 568941650 194 HIVEFLVKKK 203
Cdd:TIGR00870 275 LKLAIKYKQK 284
|
|
| PHA03095 |
PHA03095 |
ankyrin-like protein; Provisional |
56-251 |
2.47e-06 |
|
ankyrin-like protein; Provisional
Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 51.95 E-value: 2.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 56 SVGDVAKVqhILILGKSG--VNDRDKKDRTALHL-ACAYGHPEVVTLLVERKCEIDARDSESSTALIK--AVQCQEEECA 130
Cdd:PHA03095 58 SSEKVKDI--VRLLLEAGadVNAPERCGFTPLHLyLYNATTLDVIKLLIKAGADVNAKDKVGRTPLHVylSGFNINPKVI 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 131 AILLDHGADPNVMDSSGNTALHYAVYSENTSMA--AKLLAHNANIEAKNKDDLTP---MLLAVKENKQhIVEFLVKKKAS 205
Cdd:PHA03095 136 RLLLRKGADVNALDLYGMTPLAVLLKSRNANVEllRLLIDAGADVYAVDDRFRSLlhhHLQSFKPRAR-IVRELIRAGCD 214
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 568941650 206 IHAVDQLGSNRQMFEYDGKRLQRSENSNPVDNGSEDGSLTRSYNTP 251
Cdd:PHA03095 215 PAATDMLGNTPLHSMATGSSCKRSLVLPLLIAGISINARNRYGQTP 260
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
147-200 |
3.79e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 45.73 E-value: 3.79e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 568941650 147 GNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLV 200
Cdd:pfam13637 1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1122-1567 |
5.06e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.31 E-value: 5.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1122 LLRQQLDDAANKAESKD-KTIVNIQDQFQDVLTRFQAESQRhslrlEDRNQELVSECSHLRERLCQYENEKAEREVVVRQ 1200
Cdd:COG4717 46 MLLERLEKEADELFKPQgRKPELNLKELKELEEELKEAEEK-----EEEYAELQEELEELEEELEELEAELEELREELEK 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1201 LQQELADTLKKQSMSEASLEVSS------------RYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHA-EKMEDH 1267
Cdd:COG4717 121 LEKLLQLLPLYQELEALEAELAElperleeleerlEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1268 LQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLE-----CTVDQEQKRSSALEKELAEF-K 1341
Cdd:COG4717 201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLiaaalLALLGLGGSLLSLILTIAGVlF 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1342 EVLKMTKKELNEYENRELNLRQDIKnnhlemDIPVSTLIKKIDDLTAKlETASSKCLHLGKKNQLLQQELLLMRTIQKKC 1421
Cdd:COG4717 281 LVLGLLALLFLLLAREKASLGKEAE------ELQALPALEELEEEELE-ELLAALGLPPDLSPEELLELLDRIEELQELL 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1422 GKLEKNKKQLEQEVV--NLRSHMEKNMVEhSQAQQYAREVEERARQDLVEKLKQVNLFLQAQA------ASQESLEQLRE 1493
Cdd:COG4717 354 REAEELEEELQLEELeqEIAALLAEAGVE-DEEELRAALEQAEEYQELKEELEELEEQLEELLgeleelLEALDEEELEE 432
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1494 ---------NSNASVRSQMELRIKDLESQLYRMKAQEDFDKIELEKYKQLYQ-----EEFRARKSLSSKLNKTSEKLEEA 1559
Cdd:COG4717 433 eleeleeelEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAElrelaEEWAALKLALELLEEAREEYREE 512
|
....*...
gi 568941650 1560 SSKLLLEE 1567
Cdd:COG4717 513 RLPPVLER 520
|
|
| TRPV |
cd21882 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ... |
80-205 |
5.19e-06 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).
Pssm-ID: 411975 [Multi-domain] Cd Length: 600 Bit Score: 51.42 E-value: 5.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 80 KDRTALHLACAYGHPEVVTLLVERKCEIDARdseSSTALIKAVQC----------------QEEECAAILLDHGADP--- 140
Cdd:cd21882 72 QGQTALHIAIENRNLNLVRLLVENGADVSAR---ATGRFFRKSPGnlfyfgelplslaactNQEEIVRLLLENGAQPaal 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 141 NVMDSSGNTALHYAVYSEN---------TSMAAKLLAHNANI-------EAKNKDDLTPMLLAVKENKQHIVEFLVKKKA 204
Cdd:cd21882 149 EAQDSLGNTVLHALVLQADntpensafvCQMYNLLLSYGAHLdptqqleEIPNHQGLTPLKLAAVEGKIVMFQHILQREF 228
|
.
gi 568941650 205 S 205
Cdd:cd21882 229 S 229
|
|
| Ank_5 |
pfam13857 |
Ankyrin repeats (many copies); |
99-154 |
6.15e-06 |
|
Ankyrin repeats (many copies);
Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 45.03 E-value: 6.15e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 568941650 99 LLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYA 154
Cdd:pfam13857 1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
|
|
| PHA02876 |
PHA02876 |
ankyrin repeat protein; Provisional |
67-211 |
6.37e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165207 [Multi-domain] Cd Length: 682 Bit Score: 51.22 E-value: 6.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 67 LILGKSG--VNDRDKKDRTALHLAC-AYGHPEVVTLLVERKCEIDARDSESSTAL-IKAVQCQEEECAAILLDHGADPNV 142
Cdd:PHA02876 257 LLLYDAGfsVNSIDDCKNTPLHHASqAPSLSRLVPKLLERGADVNAKNIKGETPLyLMAKNGYDTENIRTLIMLGADVNA 336
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 143 MDSSGNTALHYA-VYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQ 211
Cdd:PHA02876 337 ADRLYITPLHQAsTLDRNKDIVITLLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQ 406
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
771-1432 |
6.38e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 50.98 E-value: 6.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 771 ALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEV----EARQQLEASLRTLEMELKTVKSHLNQvLEERNETQRQL--SR 844
Cdd:pfam10174 78 ALQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPelteENFRRLQSEHERQAKELFLLRKTLEE-MELRIETQKQTlgAR 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 845 EQNAR----MLQDGILASHLcKQKEIEMTQKKMTSEVSVSH------EKEKDL------LHKNQRLQDEVAVLR-----L 903
Cdd:pfam10174 157 DESIKklleMLQSKGLPKKS-GEEDWERTRRIAEAEMQLGHlevlldQKEKENihlreeLHRRNQLQPDPAKTKalqtvI 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 904 EMDTIKSHNQEKEKRYLEDikianekndnLQRMVKLNEETFTKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDV 983
Cdd:pfam10174 236 EMKDTKISSLERNIRDLED----------EVQMLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKIDQLKQELSKKESEL 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 984 ESFRSRLasalhdhaeiqtakrdleiafqrardewfrvkDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFhhtkDE 1063
Cdd:pfam10174 306 LALQTKL--------------------------------ETLTNQNSDCKQHIEVLKESLTAKEQRAAILQTEV----DA 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1064 LRektLALKHAQRDLSQTQCQMKEVehmfQDEQGKvskfmgkqesieerlaqLQSENTLLRQQLDDAANKAESKDKTIVN 1143
Cdd:pfam10174 350 LR---LRLEEKESFLNKKTKQLQDL----TEEKST-----------------LAGEIRDLKDMLDVKERKINVLQKKIEN 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1144 IQDQFQDvltrfqAESQRHSLRleDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQEladtlkKQSMSEASLEVSS 1223
Cdd:pfam10174 406 LQEQLRD------KDKQLAGLK--ERVKSLQTDSSNTDTALTTLEEALSEKERIIERLKEQ------REREDRERLEELE 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1224 RYRsnleEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSE 1303
Cdd:pfam10174 472 SLK----KENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEECSKLENQLKKAHNAE 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1304 EDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEMDIPVStlikKI 1383
Cdd:pfam10174 548 EAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIAELESLTLRQMKEQNKKVA----NI 623
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 568941650 1384 DDLTAKLETASSKCLHLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQLE 1432
Cdd:pfam10174 624 KHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGALEKTRQELD 672
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1039-1257 |
7.35e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.15 E-value: 7.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1039 LSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEhmfqdeqGKVSKFMGKQESIEERLAQLQS 1118
Cdd:COG4942 32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALE-------AELAELEKEIAELRAELEAQKE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1119 EntlLRQQLDDA-ANKAESKDKTIVNiQDQFQDVLTRFQAeSQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVV 1197
Cdd:COG4942 105 E---LAELLRALyRLGRQPPLALLLS-PEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1198 VRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREA 1257
Cdd:COG4942 180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
819-1461 |
8.04e-06 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 51.21 E-value: 8.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 819 MELKTVKSHLNQVLEERNETqrqLSREQNARMLQDGILASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEV 898
Cdd:TIGR01612 715 METATVELHLSNIENKKNEL---LDIIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAKEKDELNKYKSKISEI 791
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 899 AVL---RLEMDTIKS----HNQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTG-------QLNSLKAENTM 964
Cdd:TIGR01612 792 KNHyndQINIDNIKDedakQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINfennckeKIDSEHEQFAE 871
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 965 LSSKLDNEKQNK-----ERLETDVESFRSRLASALH-DHAEIQTAKRdleiafqraRDEWFRVKDKMNFDMSNLRDNNEV 1038
Cdd:TIGR01612 872 LTNKIKAEISDDklndyEKKFNDSKSLINEINKSIEeEYQNINTLKK---------VDEYIKICENTKESIEKFHNKQNI 942
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1039 LSQQLSK---TERKLNSLEIEFHHTKDE-LREKTLALKHAQRDLSqtqcqmkevehmFQDEQGKVSKFMGKQESIEERLA 1114
Cdd:TIGR01612 943 LKEILNKnidTIKESNLIEKSYKDKFDNtLIDKINELDKAFKDAS------------LNDYEAKNNELIKYFNDLKANLG 1010
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1115 QlQSENTLLRQ------QLDDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRH-SLRLEDRNQELVsecshlrerlcqy 1187
Cdd:TIGR01612 1011 K-NKENMLYHQfdekekATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEiGKNIELLNKEIL------------- 1076
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1188 enEKAEREVVVRQlqqELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDH 1267
Cdd:TIGR01612 1077 --EEAEINITNFN---EIKEKLKHYNFDDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQ 1151
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1268 LQKLE--------------LEKSKFEITIK--KQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKES---------LEcT 1322
Cdd:TIGR01612 1152 INDLEdvadkaisnddpeeIEKKIENIVTKidKKKNIYDEIKKLLNEIAEIEKDKTSLEEVKGINLSygknlgklfLE-K 1230
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1323 VDQEQKRSSALEKELAEFKEVLKMTKKELNEYENrELNLRQDIKNNHLEMDIPVS------TLIKKIDDLTAKLEtasSK 1396
Cdd:TIGR01612 1231 IDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIEN-EMGIEMDIKAEMETFNISHDddkdhhIISKKHDENISDIR---EK 1306
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1397 CLHLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQ---EVVNLRSHMEKNMVEH--SQAQQYAREVEE 1461
Cdd:TIGR01612 1307 SLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLylnEIANIYNILKLNKIKKiiDEVKEYTKEIEE 1376
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
51-212 |
8.43e-06 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 50.35 E-value: 8.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 51 IHKAASVGDVAKVQHILILGkSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECA 130
Cdd:PHA02874 128 LHYAIKKGDLESIKMLFEYG-ADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACI 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 131 AILLDHG-------------------------------ADPNVMDSSGNTALHYAV-YSENTSMAAKLLAHNANIEAKNK 178
Cdd:PHA02874 207 KLLIDHGnhimnkckngftplhnaiihnrsaiellinnASINDQDIDGSTPLHHAInPPCDIDIIDILLYHKADISIKDN 286
|
170 180 190
....*....|....*....|....*....|....*
gi 568941650 179 DDLTPMLLAVKE-NKQHIVEFLVKKKASIHAVDQL 212
Cdd:PHA02874 287 KGENPIDTAFKYiNKDPVIKDIIANAVLIKEADKL 321
|
|
| PTZ00322 |
PTZ00322 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
52-136 |
8.89e-06 |
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 50.67 E-value: 8.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 52 HKAASvGDVAKVQhILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAA 131
Cdd:PTZ00322 88 QLAAS-GDAVGAR-ILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQ 165
|
....*
gi 568941650 132 ILLDH 136
Cdd:PTZ00322 166 LLSRH 170
|
|
| TRPV5-6 |
cd22192 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ... |
98-213 |
1.00e-05 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.
Pssm-ID: 411976 [Multi-domain] Cd Length: 609 Bit Score: 50.40 E-value: 1.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 98 TLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDhgADP----NVMDSS---GNTALHYAVYSENTSMAAKLLAHN 170
Cdd:cd22192 35 KLLKCPSCDLFQRGALGETALHVAALYDNLEAAVVLME--AAPelvnEPMTSDlyqGETALHIAVVNQNLNLVRELIARG 112
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 568941650 171 ANIEA---------KNKDDLT-----PMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
Cdd:cd22192 113 ADVVSpratgtffrPGPKNLIyygehPLSFAACVGNEEIVRLLIEHGADIRAQDSLG 169
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
1042-1579 |
1.01e-05 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 50.51 E-value: 1.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1042 QLSKTERKLNSLEIEFHHTKDELREKTLALKhaqRDLSQTQCQMKEVehmfqdeQGKVSKfMGKQESIEERLAQLQSENT 1121
Cdd:pfam05557 10 RLSQLQNEKKQMELEHKRARIELEKKASALK---RQLDRESDRNQEL-------QKRIRL-LEKREAEAEEALREQAELN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1122 LLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQL 1201
Cdd:pfam05557 79 RLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1202 QQeladtlKKQSMSEAslevssryrsnlEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEkMEDHLQKLElekskfeit 1281
Cdd:pfam05557 159 EK------QQSSLAEA------------EQRIKELEFEIQSQEQDSEIVKNSKSELARIPE-LEKELERLR--------- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1282 ikkqsEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKEVLKMTKKELN--------- 1352
Cdd:pfam05557 211 -----EHNKHLNENIENKLLLKEEVEDLKRKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLRspedlsrri 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1353 -EYENRELNLRQD----------IKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMR------ 1415
Cdd:pfam05557 286 eQLQQREIVLKEEnssltssarqLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRailesy 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1416 ----TIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEERARQDLVE--KLKQVNLFLQAQAASQESLE 1489
Cdd:pfam05557 366 dkelTMSNYSPQLLERIEEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERElqALRQQESLADPSYSKEEVDS 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1490 QLRENSNASV-RSQMELRIKDLESQLYRMKAQEDFDkieLEKYKQLY------QEEFRARKSLSSKLNKTSEKLEEASSK 1562
Cdd:pfam05557 446 LRRKLETLELeRQRLREQKNELEMELERRCLQGDYD---PKKTKVLHlsmnpaAEAYQQRKNQLEKLQAEIERLKRLLKK 522
|
570
....*....|....*..
gi 568941650 1563 LLLEEQQNRSLLSTLST 1579
Cdd:pfam05557 523 LEDDLEQVLRLPETTST 539
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
954-1271 |
1.03e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 50.68 E-value: 1.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 954 QLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLaSALHDHAEIQTAKRDLEIAfQRARDEWFRVKDKMNFDMSNLR 1033
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELDALQERR-EALQRLAEYSWDEIDVASA-EREIAELEAELERLDASSDDLA 688
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1034 dnneVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQgkvskfmgkQESIEERL 1113
Cdd:COG4913 689 ----ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL---------RALLEERF 755
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1114 AQLQSENTL------LRQQLDDAANKAESKDKTIVNIQDQFQDvltRFQAESQRHSLRLEDrNQELVSECSHL------- 1180
Cdd:COG4913 756 AAALGDAVErelrenLEERIDALRARLNRAEEELERAMRAFNR---EWPAETADLDADLES-LPEYLALLDRLeedglpe 831
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1181 -RERLCQYENEKAEREVVvrQLQQELADTLK--KQSMSE--ASLEVSS---------RYRSNLEEEARDLKKKLGQLRSQ 1246
Cdd:COG4913 832 yEERFKELLNENSIEFVA--DLLSKLRRAIReiKERIDPlnDSLKRIPfgpgrylrlEARPRPDPEVREFRQELRAVTSG 909
|
330 340
....*....|....*....|....*
gi 568941650 1247 LQEARDQHREavHHAEKMEDHLQKL 1271
Cdd:COG4913 910 ASLFDEELSE--ARFAALKRLIERL 932
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
713-1049 |
1.53e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 50.14 E-value: 1.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 713 KRLIELKRSHCELLTGKLK--RMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQLSEKTS 790
Cdd:PTZ00121 1592 ARIEEVMKLYEEEKKMKAEeaKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE 1671
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 791 EQlRRKGEQCQSEVEARQQLEASLRTLEMELKTVKsHLNQVLEERNETQRQLSREQNARMLQdgilASHLCKQKEIEmtq 870
Cdd:PTZ00121 1672 ED-KKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE-ELKKKEAEEKKKAEELKKAEEENKIK----AEEAKKEAEED--- 1742
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 871 KKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTI--KSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEETfTKTI 948
Cdd:PTZ00121 1743 KKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVieEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEG-NLVI 1821
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 949 FQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFD 1028
Cdd:PTZ00121 1822 NDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIERE 1901
|
330 340
....*....|....*....|....
gi 568941650 1029 MSNLR---DNNEVLSQQLSKTERK 1049
Cdd:PTZ00121 1902 IPNNNmagKNNDIIDDKLDKDEYI 1925
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1327-1580 |
1.60e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.38 E-value: 1.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1327 QKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNnhlemdipvstLIKKIDDLTAKLETASSKclhlgkknql 1406
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAA-----------LERRIAALARRIRALEQE---------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1407 lqqelllMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQE 1486
Cdd:COG4942 78 -------LAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1487 SLEQLRENSNasvrsqmelRIKDLESQLYRMKAQEDFDKIELEKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLE 1566
Cdd:COG4942 151 QAEELRADLA---------ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
|
250
....*....|....
gi 568941650 1567 EQQNRSLLSTLSTR 1580
Cdd:COG4942 222 AEELEALIARLEAE 235
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
54-213 |
1.90e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 49.19 E-value: 1.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 54 AASVGDVaKVQHILILGKSGVNDRDKKDRTALHLACAYGHPEVVTLLVerkceIDARDSEsstalIKAVQCQEEECAAIL 133
Cdd:PHA02874 42 AIRSGDA-KIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLI-----DNGVDTS-----ILPIPCIEKDMIKTI 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 134 LDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKASIHAVDQLG 213
Cdd:PHA02874 111 LDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNG 190
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
1106-1363 |
2.30e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 49.52 E-value: 2.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1106 QESIEERLAQL------QSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVL-TRFQAESQRhslRLEDRNQELVSECS 1178
Cdd:PRK11281 62 QQDLEQTLALLdkidrqKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETrETLSTLSLR---QLESRLAQTLDQLQ 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1179 HLRERLCQYEN---------EKAEREVVVRQLQ-QELADTLKKQSMSEASLEVSSRYRSNLEEEARDLK----KKLGQLR 1244
Cdd:PRK11281 139 NAQNDLAEYNSqlvslqtqpERAQAALYANSQRlQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQndlqRKSLEGN 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1245 SQLQEARDQHREavhhaEKMEdHLQKLElekskfeitikkqsEEIDQLQENLSRVNLsEEDKEKLQKLTELKESLECTVD 1324
Cdd:PRK11281 219 TQLQDLLQKQRD-----YLTA-RIQRLE--------------HQLQLLQEAINSKRL-TLSEKTVQEAQSQDEAARIQAN 277
|
250 260 270
....*....|....*....|....*....|....*....
gi 568941650 1325 QEQKRSSALEKELAEFkeVLKMTKKeLNEYENRELNLRQ 1363
Cdd:PRK11281 278 PLVAQELEINLQLSQR--LLKATEK-LNTLTQQNLRVKN 313
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1099-1363 |
2.43e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 49.24 E-value: 2.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1099 VSKFMGKQESIEERLAQLQSENTLLR----QQLDDAANKAESKDKTIVNiqdqfqDVLTRFQAESQRHS----LRLEDRN 1170
Cdd:COG3206 73 LSSLSASDSPLETQIEILKSRPVLERvvdkLNLDEDPLGEEASREAAIE------RLRKNLTVEPVKGSnvieISYTSPD 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1171 QEL-------VSEcSHLRERLcqyENEKAEREVVVRQLQQELADTLKKQSMSEASLEvssRYRS-----NLEEEARDLKK 1238
Cdd:COG3206 147 PELaaavanaLAE-AYLEQNL---ELRREEARKALEFLEEQLPELRKELEEAEAALE---EFRQknglvDLSEEAKLLLQ 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1239 KLGQLRSQLQEARDQHREAVHHAEKMEDhlqklELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKE--------KLQ 1310
Cdd:COG3206 220 QLSELESQLAEARAELAEAEARLAALRA-----QLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSarytpnhpDVI 294
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 568941650 1311 KLTELKESLECTVDQEQKRS-SALEKELAEFKEVLKMTKKELNEYENRELNLRQ 1363
Cdd:COG3206 295 ALRAQIAALRAQLQQEAQRIlASLEAELEALQAREASLQAQLAQLEARLAELPE 348
|
|
| Ank_4 |
pfam13637 |
Ankyrin repeats (many copies); |
51-101 |
2.81e-05 |
|
Ankyrin repeats (many copies);
Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 43.03 E-value: 2.81e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 568941650 51 IHKAASVGDVAKVQHILILGKSgVNDRDKKDRTALHLACAYGHPEVVTLLV 101
Cdd:pfam13637 5 LHAAAASGHLELLRLLLEKGAD-INAVDGNGETALHFAASNGNVEVLKLLL 54
|
|
| PHA02874 |
PHA02874 |
ankyrin repeat protein; Provisional |
95-206 |
2.94e-05 |
|
ankyrin repeat protein; Provisional
Pssm-ID: 165205 [Multi-domain] Cd Length: 434 Bit Score: 48.42 E-value: 2.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 95 EVVTLLVERKCEIDARDSESSTALIKAVQCQEEECAAILLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIE 174
Cdd:PHA02874 105 DMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYAN 184
|
90 100 110
....*....|....*....|....*....|..
gi 568941650 175 AKNKDDLTPMLLAVKENKQHIVEFLVKKKASI 206
Cdd:PHA02874 185 VKDNNGESPLHNAAEYGDYACIKLLIDHGNHI 216
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
1038-1560 |
3.06e-05 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 49.05 E-value: 3.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1038 VLSQQLSKTERKLNSLEIEFHHTKDELRektlalkhAQRDLSQTqcqmkeVEHMFQDEQGKVSKFMGKQESIEERLAQLQ 1117
Cdd:pfam10174 57 VLKEQYRVTQEENQHLQLTIQALQDELR--------AQRDLNQL------LQQDFTTSPVDGEDKFSTPELTEENFRRLQ 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1118 S-------ENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLED-----RNQELVSECSHLRERLC 1185
Cdd:pfam10174 123 SeherqakELFLLRKTLEEMELRIETQKQTLGARDESIKKLLEMLQSKGLPKKSGEEDwertrRIAEAEMQLGHLEVLLD 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1186 QYENEKAE-REVVVR--QLQQELADTLKKQSMseasLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAE 1262
Cdd:pfam10174 203 QKEKENIHlREELHRrnQLQPDPAKTKALQTV----IEMKDTKISSLERNIRDLEDEVQMLKTNGLLHTEDREEEIKQME 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1263 KMEDH--LQKLELEKSKFEITiKKQSEeIDQLQENLSRVNLSEEDKEklQKLTELKESLECtvdqEQKRSSALEKELAEF 1340
Cdd:pfam10174 279 VYKSHskFMKNKIDQLKQELS-KKESE-LLALQTKLETLTNQNSDCK--QHIEVLKESLTA----KEQRAAILQTEVDAL 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1341 KEVLKMTKKELNEYENRELNLRQDiknnhlemdipVSTLIKKIDDLTAKLETASSKCLHLGKKnqlLQQELLLMRTIQKK 1420
Cdd:pfam10174 351 RLRLEEKESFLNKKTKQLQDLTEE-----------KSTLAGEIRDLKDMLDVKERKINVLQKK---IENLQEQLRDKDKQ 416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1421 CGKLEKNKKQLEQEVVNLRSH---MEKNMVEHS---QAQQYAREVEERARQDLVEKLKQVNL-------FLQAQAASQE- 1486
Cdd:pfam10174 417 LAGLKERVKSLQTDSSNTDTAlttLEEALSEKEriiERLKEQREREDRERLEELESLKKENKdlkekvsALQPELTEKEs 496
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1487 SLEQLRE--NSNASVRSQMELRIKDLESQLYRMKaqEDFDKIELEKYK-QLYQEEFRARKSLSSKL----NKTSEKLEEA 1559
Cdd:pfam10174 497 SLIDLKEhaSSLASSGLKKDSKLKSLEIAVEQKK--EECSKLENQLKKaHNAEEAVRTNPEINDRIrlleQEVARYKEES 574
|
.
gi 568941650 1560 S 1560
Cdd:pfam10174 575 G 575
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
689-1117 |
3.41e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.91 E-value: 3.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 689 IEHLRLECKD----TASLLKIRDAVYSYKRLIELKRSHCELLTG---KLKRMENKYKGLQKEMSETEEVKSRLEH---EK 758
Cdd:PRK03918 268 IEELKKEIEEleekVKELKELKEKAEEYIKLSEFYEEYLDELREiekRLSRLEEEINGIEERIKELEEKEERLEElkkKL 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 759 VGWEQELCRLR-------FALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQV 831
Cdd:PRK03918 348 KELEKRLEELEerhelyeEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKA 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 832 LEERNETQ-------RQLSREQNARmlqdgILASHLCKQKEIEMTQKKMTSEVSvSHEKEKDLLHKNQRLQDEVAVLRLE 904
Cdd:PRK03918 428 IEELKKAKgkcpvcgRELTEEHRKE-----LLEEYTAELKRIEKELKEIEEKER-KLRKELRELEKVLKKESELIKLKEL 501
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 905 MDTIKSHNQEKEKRYLEDIKIANEKNDNL-QRMVKLNEEtfTKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLET-- 981
Cdd:PRK03918 502 AEQLKELEEKLKKYNLEELEKKAEEYEKLkEKLIKLKGE--IKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKel 579
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 982 ---------DVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEwfRVKDKMNFDMSNLRDNN-EVLSQQLSKTERKLN 1051
Cdd:PRK03918 580 eelgfesveELEERLKELEPFYNEYLELKDAEKELEREEKELKKL--EEELDKAFEELAETEKRlEELRKELEELEKKYS 657
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941650 1052 slEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQD---EQGKVSKFMGKQESIEERLAQLQ 1117
Cdd:PRK03918 658 --EEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKlkeELEEREKAKKELEKLEKALERVE 724
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
82-111 |
3.71e-05 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 42.28 E-value: 3.71e-05
10 20 30
....*....|....*....|....*....|.
gi 568941650 82 RTALHLACA-YGHPEVVTLLVERKCEIDARD 111
Cdd:pfam00023 3 NTPLHLAAGrRGNLEIVKLLLSKGADVNARD 33
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
736-1345 |
4.01e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 48.68 E-value: 4.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 736 KYKGLQKEMSETEEVKSRLEHEKVGWEQElcRLRFALKQEEEKRRSADQlsektSEQLRRKGEQCQSEV-EARQQL---E 811
Cdd:pfam12128 242 EFTKLQQEFNTLESAELRLSHLHFGYKSD--ETLIASRQEERQETSAEL-----NQLLRTLDDQWKEKRdELNGELsaaD 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 812 ASLRTLEMELKTVKSHLNQVLEERNET----QRQLSREQNARMLQDGILASHLCKQKEIEMTQKKMTSEVSVSHEKEKDL 887
Cdd:pfam12128 315 AAVAKDRSELEALEDQHGAFLDADIETaaadQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAG 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 888 LHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTKTIFQYTGQLNSLKAENTMLSS 967
Cdd:pfam12128 395 IKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIE 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 968 KLDNEKQ----NKERLETDVESFRSRLASALHDH-------AEIQTAKRDLE----------IAFQRA-----RDEWFRV 1021
Cdd:pfam12128 475 RAREEQEaanaEVERLQSELRQARKRRDQASEALrqasrrlEERQSALDELElqlfpqagtlLHFLRKeapdwEQSIGKV 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1022 KDKMNFDMSNL--RDNNEVLSQQLSKTERKLNSLEI---EFHHTKDELREKTLALKHAQRDLSQTQCQMKEvehmfqdEQ 1096
Cdd:pfam12128 555 ISPELLHRTDLdpEVWDGSVGGELNLYGVKLDLKRIdvpEWAASEEELRERLDKAEEALQSAREKQAAAEE-------QL 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1097 GKVSKFMGKQESIEERLAQL--QSENTLLR-----QQLDDAANKA--ESKDKTIVNIQD----------QFQDVLTRFQA 1157
Cdd:pfam12128 628 VQANGELEKASREETFARTAlkNARLDLRRlfdekQSEKDKKNKAlaERKDSANERLNSleaqlkqldkKHQAWLEEQKE 707
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1158 ESQRHSLRLEDRNQELVSECSHLRERLCQ-YENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLE---EEA 1233
Cdd:pfam12128 708 QKREARTEKQAYWQVVEGALDAQLALLKAaIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLErkiERI 787
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1234 RDLKKKLGQLRSQLQEARDQHREAV--------HHAEKMEDHL-----------QKLELEKSKFEITIKKQSEEIDQLQE 1294
Cdd:pfam12128 788 AVRRQEVLRYFDWYQETWLQRRPRLatqlsnieRAISELQQQLarliadtklrrAKLEMERKASEKQQVRLSENLRGLRC 867
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....
gi 568941650 1295 NLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKR---SSALEKELAEFKEVLK 1345
Cdd:pfam12128 868 EMSKLATLKEDANSEQAQGSIGERLAQLEDLKLKRdylSESVKKYVEHFKNVIA 921
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1229-1396 |
4.88e-05 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 46.84 E-value: 4.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1229 LEEEARDLKKKLGQLRSQLQEARDQHreavhhaEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEdkek 1308
Cdd:COG1579 22 LEHRLKELPAELAELEDELAALEARL-------EAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE---- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1309 LQKLTELKESLEctvdqeqKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEMDIPVSTLIKKIDDLTA 1388
Cdd:COG1579 91 YEALQKEIESLK-------RRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEA 163
|
....*...
gi 568941650 1389 KLETASSK 1396
Cdd:COG1579 164 EREELAAK 171
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
737-1482 |
5.13e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 48.30 E-value: 5.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 737 YKGLQKEMSETEEVKSRLEHEKVGwEQELCRLRFALKQEEekRRSADQLsektseqlrrkgEQCQsevEARQQLEASLRT 816
Cdd:pfam12128 233 IAGIMKIRPEFTKLQQEFNTLESA-ELRLSHLHFGYKSDE--TLIASRQ------------EERQ---ETSAELNQLLRT 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 817 LEMELKTVKSHLNQVLE------ERNETQRQLSREQNARMLQDGILASHLCKQKEiemtqKKMTSEVSVSHEKEKDLLHK 890
Cdd:pfam12128 295 LDDQWKEKRDELNGELSaadaavAKDRSELEALEDQHGAFLDADIETAAADQEQL-----PSWQSELENLEERLKALTGK 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 891 NQRLQDevavlrlEMDTIKSHNQEKEKRYLEDIkiaNEKNDNlQRMVKLNEETFTKTIFQytGQLNSLKAEntmLSSKLD 970
Cdd:pfam12128 370 HQDVTA-------KYNRRRSKIKEQNNRDIAGI---KDKLAK-IREARDRQLAVAEDDLQ--ALESELREQ---LEAGKL 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 971 NEKQNKERLETDVESFRSRLASALHDhAEIQTAKRDLEIAFQRARDEwfrvkdkmnfdmsnlrdnnevlsqqLSKTERKL 1050
Cdd:pfam12128 434 EFNEEEYRLKSRLGELKLRLNQATAT-PELLLQLENFDERIERAREE-------------------------QEAANAEV 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1051 NSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESI-EERLAQLQSENTLLRQQLDD 1129
Cdd:pfam12128 488 ERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDwEQSIGKVISPELLHRTDLDP 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1130 AANKAESKDktivniQDQFQDVLTRFQAESQRHSLRLEDRnqelvsecshLRERLCQYENEKAEREVVVRQLQQELADTL 1209
Cdd:pfam12128 568 EVWDGSVGG------ELNLYGVKLDLKRIDVPEWAASEEE----------LRERLDKAEEALQSAREKQAAAEEQLVQAN 631
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1210 KKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHReavhhaEKMEDHLQKLELEKSKFEITIKKQSEEI 1289
Cdd:pfam12128 632 GELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERK------DSANERLNSLEAQLKQLDKKHQAWLEEQ 705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1290 -DQLQENlsrvnlSEEDKEKLQKLTELKESLECTVDQE-QKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKN 1367
Cdd:pfam12128 706 kEQKREA------RTEKQAYWQVVEGALDAQLALLKAAiAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRT 779
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1368 NHLEM--------------DIPVSTLIKKIDDLTAKLETASSKCLHL-GKKNQLLQQELLLMRTIQKKCGKLEKNKKQLE 1432
Cdd:pfam12128 780 LERKIeriavrrqevlryfDWYQETWLQRRPRLATQLSNIERAISELqQQLARLIADTKLRRAKLEMERKASEKQQVRLS 859
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|..
gi 568941650 1433 QEVVNLRSHMEK--NMVEHSQAQQYAREVEERARQdlVEKLKQVNLFLQAQA 1482
Cdd:pfam12128 860 ENLRGLRCEMSKlaTLKEDANSEQAQGSIGERLAQ--LEDLKLKRDYLSESV 909
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1276-1578 |
6.09e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.14 E-value: 6.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1276 SKFEITIKKQSEEIDQLQENLSRVNLSE--------------EDKEKLQKLTELKESLECTVDQEQKRS-----SALEKE 1336
Cdd:TIGR02169 166 AEFDRKKEKALEELEEVEENIERLDLIIdekrqqlerlrrerEKAERYQALLKEKREYEGYELLKEKEAlerqkEAIERQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1337 LAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEMDIPVS----TLIKKIDDLTAKLETASSKclhLGKKNQLLQQELL 1412
Cdd:TIGR02169 246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeeqlRVKEKIGELEAEIASLERS---IAEKERELEDAEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1413 LMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQaqqyAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQLR 1492
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAE----LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1493 ENSNASVRSQMEL--RIKDLESQLYRMKAqedfdkiELEKYKQLYQEEFRARKSLSSKLNKTSEKLEEASSKLLLEEQQN 1570
Cdd:TIGR02169 399 REINELKRELDRLqeELQRLSEELADLNA-------AIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQEL 471
|
....*...
gi 568941650 1571 RSLLSTLS 1578
Cdd:TIGR02169 472 YDLKEEYD 479
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
713-1385 |
6.35e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.21 E-value: 6.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 713 KRLIELKRSHCELLTGKLKRMENKYKGlQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQEEEKRRSADQL---SEKT 789
Cdd:PTZ00121 1212 RKAEEARKAEDAKKAEAVKKAEEAKKD-AEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELkkaEEKK 1290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 790 SEQLRRKGEQCQSEVEARQQLEASLRTleMELKTVKSHLNQVLEERNETQRQLSREQNARMLQDGILASHLCKQKEIEMT 869
Cdd:PTZ00121 1291 KADEAKKAEEKKKADEAKKKAEEAKKA--DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEA 1368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 870 QKKMTSEVSVSHE---KEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKE-----KRYLEDIKIANEKNDNLQRMVKLnE 941
Cdd:PTZ00121 1369 AEKKKEEAKKKADaakKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKkadeaKKKAEEKKKADEAKKKAEEAKKA-D 1447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 942 ETFTKTIFQYTGQLNSLKAENTMLSSKLDN---EKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEW 1018
Cdd:PTZ00121 1448 EAKKKAEEAKKAEEAKKKAEEAKKADEAKKkaeEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA 1527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1019 FRVKDKMNFDmsNLRDNNEVL-SQQLSKTERKLNSLEI-EFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQ 1096
Cdd:PTZ00121 1528 KKAEEAKKAD--EAKKAEEKKkADELKKAEELKKAEEKkKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1097 GKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTivnIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSE 1176
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKA---EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKK 1682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1177 CSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARD-QHR 1255
Cdd:PTZ00121 1683 AEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKiAHL 1762
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1256 EAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENL--SRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSAL 1333
Cdd:PTZ00121 1763 KKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIfdNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQ 1842
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|...
gi 568941650 1334 EKELAEFKEVLKMTKKELNEYENRELNLRQDIKN-NHLEMDIPVSTLIKKIDD 1385
Cdd:PTZ00121 1843 LEEADAFEKHKFNKNNENGEDGNKEADFNKEKDLkEDDEEEIEEADEIEKIDK 1895
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
876-1298 |
7.25e-05 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 47.38 E-value: 7.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 876 EVSVSHEKEKDLLHKNQRLQDEVAVLrlemdtikshnQEKEKRYLEDIKIANEKNDNLQRMVKLNEETFTKtIFQYTGQL 955
Cdd:pfam05622 1 DLSEAQEEKDELAQRCHELDQQVSLL-----------QEEKNSLQQENKKLQERLDQLESGDDSGTPGGKK-YLLLQKQL 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 956 NSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIaFQRARDEWFRV-------KDKMNfD 1028
Cdd:pfam05622 69 EQLQEENFRLETARDDYRIKCEELEKEVLELQHRNEELTSLAEEAQALKDEMDI-LRESSDKVKKLeatvetyKKKLE-D 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1029 MSNLRdnNEVLSQQLSKTERKLNSLEIEfhhtkDELReKTLALKhAQRDLSQTQCQmkEVEHMFQDEQGKVSKFMGKQES 1108
Cdd:pfam05622 147 LGDLR--RQVKLLEERNAEYMQRTLQLE-----EELK-KANALR-GQLETYKRQVQ--ELHGKLSEESKKADKLEFEYKK 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1109 IEERLAQLQSENTLLRQQLDdaANKAESKDKTIVNIQdqfQDVLTRFQAESQRHSLRLEDRNQELVSecSHLRERLcqye 1188
Cdd:pfam05622 216 LEEKLEALQKEKERLIIERD--TLRETNEELRCAQLQ---QAELSQADALLSPSSDPGDNLAAEIMP--AEIREKL---- 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1189 nEKAEREVVVRQLQQELADTlKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAE------ 1262
Cdd:pfam05622 285 -IRLQHENKMLRLGQEGSYR-ERLTELQQLLEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEdssllk 362
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 568941650 1263 -KMEDHLQKL-----ELEKSKFEITIKKQ------SEEIDQLQENLSR 1298
Cdd:pfam05622 363 qKLEEHLEKLheaqsELQKKKEQIEELEPkqdsnlAQKIDELQEALRK 410
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
977-1354 |
7.70e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 47.20 E-value: 7.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 977 ERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEI- 1055
Cdd:pfam07888 30 ELLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSAs 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1056 --EFHHTKDELREKTLALKHAQRDLSQ------TQCQMKEVEHMFQDEQGKVSKFMGKQESIEER-----LAQLQSENTL 1122
Cdd:pfam07888 110 seELSEEKDALLAQRAAHEARIRELEEdiktltQRVLERETELERMKERAKKAGAQRKEEEAERKqlqakLQQTEEELRS 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1123 LRQQLDDAANKAESKDKTIVNIQDQFQdVLTRFQAESQRHSLRLEDRNQELVSecshLRERLCQYENEkaerevvVRQLQ 1202
Cdd:pfam07888 190 LSKEFQELRNSLAQRDTQVLQLQDTIT-TLTQKLTTAHRKEAENEALLEELRS----LQERLNASERK-------VEGLG 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1203 QELADTLKKQSMSEASLevssrYRSNLeeEARDLKKKLGQLRSQLQEAR---DQHREAVHH-AEKMEDHLQKLELEKSKF 1278
Cdd:pfam07888 258 EELSSMAAQRDRTQAEL-----HQARL--QAAQLTLQLADASLALREGRarwAQERETLQQsAEADKDRIEKLSAELQRL 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1279 EITIKKQSEEIDQLQENL------SRVNLSEEDKEklqkLTELKESLEctvdqeqkrssALEKElaefKEVLKMTKKELN 1352
Cdd:pfam07888 331 EERLQEERMEREKLEVELgrekdcNRVQLSESRRE----LQELKASLR-----------VAQKE----KEQLQAEKQELL 391
|
..
gi 568941650 1353 EY 1354
Cdd:pfam07888 392 EY 393
|
|
| TRPV3 |
cd22194 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a ... |
80-207 |
7.75e-05 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 3; TRPV3 is a temperature-sensitive Transient Receptor Potential (TRP) ion channel that is activated by warm temperatures, synthetic small-molecule chemicals, and natural compounds from plants. TRPV3 function is regulated by physiological factors such as extracellular divalent cations and acidic pH, intracellular adenosine triphosphate, membrane voltage, and arachidonic acid. It is expressed in both neuronal and non-neuronal tissues including epidermal keratinocytes, epithelial cells in the gut, endothelial cells in blood vessels, and neurons in dorsal root ganglia and CNS. TRPV3 null mice have abnormal hair morphogenesis and compromised skin barrier function. It may play roles in inflammatory skin disorders, such as itch and pain sensation. TRPV3 is also expressed by many neuronal and non-neuronal tissues, showing that TRPV3 might play roles in other unknown cellular and physiological functions. TRPV3 belongs to the vanilloid TRP subfamily (TRPV), named after the founding member vanilloid receptor 1 (TRPV1). The structure of TRPV shows the typical topology features of all TRP ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.
Pssm-ID: 411978 [Multi-domain] Cd Length: 680 Bit Score: 47.45 E-value: 7.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 80 KDRTALHLACAYGHPEVVTLLVERKCEIDARDSE--------------SSTALIKAVQCQEEECAAILLDHGADPNVM-D 144
Cdd:cd22194 140 EGQTALNIAIERRQGDIVKLLIAKGADVNAHAKGvffnpkykhegfyfGETPLALAACTNQPEIVQLLMEKESTDITSqD 219
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941650 145 SSGNTALHYAVY----SEN-----TSMAAKLL--AHNANIEA-KNKDDLTPMLLAVKENK----QHIVEFLVKKKASIH 207
Cdd:cd22194 220 SRGNTVLHALVTvaedSKTqndfvKRMYDMILlkSENKNLETiRNNEGLTPLQLAAKMGKaeilKYILSREIKEKPNRS 298
|
|
| Ank |
pfam00023 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
147-178 |
1.73e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.
Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 40.35 E-value: 1.73e-04
10 20 30
....*....|....*....|....*....|...
gi 568941650 147 GNTALHYAVYSE-NTSMAAKLLAHNANIEAKNK 178
Cdd:pfam00023 2 GNTPLHLAAGRRgNLEIVKLLLSKGADVNARDK 34
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
1183-1344 |
1.76e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.92 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1183 RLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQhREavhhAE 1262
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNN-KE----YE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1263 KMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRvnLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKE 1342
Cdd:COG1579 93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAE--LEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAA 170
|
..
gi 568941650 1343 VL 1344
Cdd:COG1579 171 KI 172
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1071-1257 |
1.92e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.59 E-value: 1.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1071 LKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESK----DKTIVNIQ- 1145
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERreelGERARALYr 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1146 --------------DQFQDVLTRFQAESqrhslRLEDRNQELVSECSHLRERLcqyENEKAEREVVVRQLQQELADTLKK 1211
Cdd:COG3883 98 sggsvsyldvllgsESFSDFLDRLSALS-----KIADADADLLEELKADKAEL---EAKKAELEAKLAELEALKAELEAA 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 568941650 1212 QSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREA 1257
Cdd:COG3883 170 KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
925-1345 |
1.93e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 46.49 E-value: 1.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 925 IANEKNDNLQRMVKLNEETFTKTifqytGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASAlhdhaeiQTAK 1004
Cdd:PRK04863 277 HANERRVHLEEALELRRELYTSR-----RQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLV-------QTAL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1005 RDLEiAFQRARDEWfrvkDKMNFdmsNLRDNNEVL---SQQLSKTERKLNSLEIEFHHTK----------DELREKTLAL 1071
Cdd:PRK04863 345 RQQE-KIERYQADL----EELEE---RLEEQNEVVeeaDEQQEENEARAEAAEEEVDELKsqladyqqalDVQQTRAIQY 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1072 KHAQRDL--SQTQCQMKEVEhmfqdeqgkvskfmgkQESIEERLAQLQSENTLLRQQLDDAANKAESKDktivNIQDQFQ 1149
Cdd:PRK04863 417 QQAVQALerAKQLCGLPDLT----------------ADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQ----AAHSQFE 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1150 dvltrfQAESQRHSLRLE-DRNQELvsecSHLRERLCQYENEK--AEREVVVRQLQQELADTLKKQSMSEASL-EVSSRY 1225
Cdd:PRK04863 477 ------QAYQLVRKIAGEvSRSEAW----DVARELLRRLREQRhlAEQLQQLRMRLSELEQRLRQQQRAERLLaEFCKRL 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1226 RSNLEEEArDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEitikKQSEEIDQLQENLSRVN-LSEE 1304
Cdd:PRK04863 547 GKNLDDED-ELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLA----ARAPAWLAAQDALARLReQSGE 621
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 568941650 1305 DKEKLQKLTELKESLectvdQEQKRSSALEK-ELAEFKEVLK 1345
Cdd:PRK04863 622 EFEDSQDVTEYMQQL-----LERERELTVERdELAARKQALD 658
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
882-1342 |
2.05e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 2.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 882 EKEKDLLHKNQRLQDEVAVLRLEMDTIKSHN-QEKEKRYLEDIKIANEKNDNLQRmVKLNEETFTKTIFQYTGQLNSLKA 960
Cdd:COG4717 52 EKEADELFKPQGRKPELNLKELKELEEELKEaEEKEEEYAELQEELEELEEELEE-LEAELEELREELEKLEKLLQLLPL 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 961 ENTM--LSSKLDNEKQNKERLETDVESFRSRLASALHDHAEIQTAKRDLEIAFQRARDEWFRvkdkmnfDMSNLRDNNEV 1038
Cdd:COG4717 131 YQELeaLEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEE-------ELQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1039 LSQQLSKTERKLNSLEIEFHHTKDELR--EKTLALKHAQRDLSQTQCQMK------EVEHMFQDEQGKVSKFMGKQESIE 1110
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEqlENELEAAALEERLKEARLLLLiaaallALLGLGGSLLSLILTIAGVLFLVL 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1111 ERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAEsqrhslrlEDRNQELVSECSHLRERLCQYENE 1190
Cdd:COG4717 284 GLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLP--------PDLSPEELLELLDRIEELQELLRE 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1191 KAEREvvvRQLQQELADTLKKQSMSEASLEVSSRYRSNLE--EEARDLKKKLGQLRSQLQEARD--QHREAVHHAEKMED 1266
Cdd:COG4717 356 AEELE---EELQLEELEQEIAALLAEAGVEDEEELRAALEqaEEYQELKEELEELEEQLEELLGelEELLEALDEEELEE 432
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941650 1267 HLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSA---LEKELAEFKE 1342
Cdd:COG4717 433 ELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQELEELKAELRELAEEWAALKLAlelLEEAREEYRE 511
|
|
| Ank_3 |
pfam13606 |
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
82-109 |
3.61e-04 |
|
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.
Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 39.16 E-value: 3.61e-04
10 20
....*....|....*....|....*...
gi 568941650 82 RTALHLACAYGHPEVVTLLVERKCEIDA 109
Cdd:pfam13606 3 NTPLHLAARNGRLEIVKLLLENGADINA 30
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1062-1253 |
4.09e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 45.33 E-value: 4.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1062 DELREKTLALKHAQRDLSQTQCQMKEV----EHM-FQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAES 1136
Cdd:PRK04863 938 EQLKQDYQQAQQTQRDAKQQAFALTEVvqrrAHFsYEDAAEMLAKNSDLNEKLRQRLEQAEQERTRAREQLRQAQAQLAQ 1017
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1137 KDKTivniqdqFQDVLTRFQAESQRHslrledrnQELVSECSHLRERLCQYENEKAerevvvRQLQQELADTLKKQSMSE 1216
Cdd:PRK04863 1018 YNQV-------LASLKSSYDAKRQML--------QELKQELQDLGVPADSGAEERA------RARRDELHARLSANRSRR 1076
|
170 180 190
....*....|....*....|....*....|....*..
gi 568941650 1217 ASLEvssRYRSNLEEEARDLKKKLGQLRSQLQEARDQ 1253
Cdd:PRK04863 1077 NQLE---KQLTFCEAEMDNLTKKLRKLERDYHEMREQ 1110
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
998-1251 |
4.15e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 45.01 E-value: 4.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 998 AEIQTAKRDLEIAFQRARDewFRVKDkmnfDMSNLRDNNEVLSQQLSKTERKLNSLEIEfhhtkdeLREKTLALKHAQRD 1077
Cdd:COG3206 182 EQLPELRKELEEAEAALEE--FRQKN----GLVDLSEEAKLLLQQLSELESQLAEARAE-------LAEAEARLAALRAQ 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1078 LSQTQCQMKEVehmfqdeqgkvskfmgkqeSIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQA 1157
Cdd:COG3206 249 LGSGPDALPEL-------------------LQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQ 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1158 ESQRhslrledrnqelvsecshlreRLCQYENEKAEREVVVRQLQQELADtLKKQSMSEASLEVssRYRsNLEEEARDLK 1237
Cdd:COG3206 310 EAQR---------------------ILASLEAELEALQAREASLQAQLAQ-LEARLAELPELEA--ELR-RLEREVEVAR 364
|
250
....*....|....
gi 568941650 1238 KKLGQLRSQLQEAR 1251
Cdd:COG3206 365 ELYESLLQRLEEAR 378
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
1220-1353 |
4.27e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 45.07 E-value: 4.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1220 EVSSRYR---SNLEEEARDLKKKLGQLRSQLQEA-RDQHREAVHHAEKMEDHLQKLElekskfeitikkqsEEIDQLQEN 1295
Cdd:COG0542 397 EAAARVRmeiDSKPEELDELERRLEQLEIEKEALkKEQDEASFERLAELRDELAELE--------------EELEALKAR 462
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 568941650 1296 LsrvnlsEEDKEKLQKLTELKESLEctvdQEQKRSSALEKELAEFKEVLKMTKKELNE 1353
Cdd:COG0542 463 W------EAEKELIEEIQELKEELE----QRYGKIPELEKELAELEEELAELAPLLRE 510
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
726-1320 |
4.34e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 45.17 E-value: 4.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 726 LTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKVGWEQELCRLRFALKQE-------EEKRRSADQLSEKTSEQLRRKGE 798
Cdd:pfam01576 487 LSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDagtlealEEGKKRLQRELEALTQQLEEKAA 566
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 799 QCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSREQN--ARMLQDGILASHLCKQKEiemtqkkmTSE 876
Cdd:pfam01576 567 AYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAisARYAEERDRAEAEAREKE--------TRA 638
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 877 VSVSHEKEKDLLHKNQrLQDEVAVLRLEMDTIKS---------HNQEKEKRYLEdiKIANEKNDNLQRMV-KLNEETFTK 946
Cdd:pfam01576 639 LSLARALEEALEAKEE-LERTNKQLRAEMEDLVSskddvgknvHELERSKRALE--QQVEEMKTQLEELEdELQATEDAK 715
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 947 TIFQYTGQlnSLKAENTMLSSKLDNEKQNKER--------LETDVESFRSRLASALHDHAEIQTAKRDLEI---AFQRAR 1015
Cdd:pfam01576 716 LRLEVNMQ--ALKAQFERDLQARDEQGEEKRRqlvkqvreLEAELEDERKQRAQAVAAKKKLELDLKELEAqidAANKGR 793
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1016 DEWFRVKDKMNFDMSNL-------RDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQcqmkev 1088
Cdd:pfam01576 794 EEAVKQLKKLQAQMKDLqreleeaRASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELA------ 867
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1089 EHMFQDEQGKVSKFMGKQEsIEERLAQLQSEntllrqqLDDAANKAESKDKTIVNIQDQFQDVLTRFQAEsQRHSLRLED 1168
Cdd:pfam01576 868 DEIASGASGKSALQDEKRR-LEARIAQLEEE-------LEEEQSNTELLNDRLRKSTLQVEQLTTELAAE-RSTSQKSES 938
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1169 RNQELVSECSHLRERLcqyenekAEREVVVRQLQQELADTLK-KQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQL 1247
Cdd:pfam01576 939 ARQQLERQNKELKAKL-------QEMEGTVKSKFKSSIAALEaKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVLLQV 1011
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568941650 1248 QEARdqhreavHHAEKMEDHLQKLELEKSKfeitIKKQSEEIdqlQENLSRVNLSeedKEKLQK-LTELKESLE 1320
Cdd:pfam01576 1012 EDER-------RHADQYKDQAEKGNSRMKQ----LKRQLEEA---EEEASRANAA---RRKLQReLDDATESNE 1068
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1070-1277 |
4.40e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 4.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1070 ALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQ-------LQSENTLLRQQLDDAANKAESKDKTIV 1142
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlarriraLEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1143 NIQDQFQDVLTRFQAESQRHSLRL----ED-----RNQELVSECS-HLRERLCQYENEKAEREVVVRQLQQE---LADTL 1209
Cdd:COG4942 101 AQKEELAELLRALYRLGRQPPLALllspEDfldavRRLQYLKYLApARREQAEELRADLAELAALRAELEAEraeLEALL 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568941650 1210 KKQsmseaslevsSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSK 1277
Cdd:COG4942 181 AEL----------EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1041-1559 |
5.07e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 5.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1041 QQLSKTERKLNSLEiefhhtkdELREKTLALKHAQRDLSQTQcQMKEVEHMFQDEQgKVSKFMGKQESIEERLAQLQSEN 1120
Cdd:COG4913 242 EALEDAREQIELLE--------PIRELAERYAAARERLAELE-YLRAALRLWFAQR-RLELLEAELEELRAELARLEAEL 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1121 TLLRQQLDDAAnkaESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQElvsecshlRERLcqyenekaerEVVVRQ 1200
Cdd:COG4913 312 ERLEARLDALR---EELDELEAQIRGNGGDRLEQLEREIERLERELEERERR--------RARL----------EALLAA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1201 LQQELADT----LKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKL----- 1271
Cdd:COG4913 371 LGLPLPASaeefAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALrdala 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1272 -ELEKSKFE-------ITIKKQSEE----------------------IDQLQENLSRVNLS--------EEDKEKLQKLT 1313
Cdd:COG4913 451 eALGLDEAElpfvgelIEVRPEEERwrgaiervlggfaltllvppehYAAALRWVNRLHLRgrlvyervRTGLPDPERPR 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1314 ELKESLECTVD-QEQKRSSALEKELAEFKEVLK------------------MTKkelNEYENRELNLRQDIKNNHLemdI 1374
Cdd:COG4913 531 LDPDSLAGKLDfKPHPFRAWLEAELGRRFDYVCvdspeelrrhpraitragQVK---GNGTRHEKDDRRRIRSRYV---L 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1375 PVSTlIKKIDDLTAKLETASSKCLHLGKKNQLLQQELLLMRTIQKKCGKL------EKNKKQLEQEVVNL---RSHMEKN 1445
Cdd:COG4913 605 GFDN-RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLaeyswdEIDVASAEREIAELeaeLERLDAS 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1446 MVEHSQAQQYAREVEERaRQDLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQMELRIKDLESQLYRMKAQEDFDK 1525
Cdd:COG4913 684 SDDLAALEEQLEELEAE-LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDA 762
|
570 580 590
....*....|....*....|....*....|....
gi 568941650 1526 IELEKYKQLYQEefraRKSLSSKLNKTSEKLEEA 1559
Cdd:COG4913 763 VERELRENLEER----IDALRARLNRAEEELERA 792
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
80-109 |
5.44e-04 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 38.72 E-value: 5.44e-04
10 20 30
....*....|....*....|....*....|
gi 568941650 80 KDRTALHLACAYGHPEVVTLLVERKCEIDA 109
Cdd:smart00248 1 DGRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
778-1172 |
6.57e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 44.34 E-value: 6.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 778 KRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELK---TVKSHLNQVLEERNETQRQLSREQNARMLQDg 854
Cdd:pfam17380 286 ERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDrqaAIYAEQERMAMERERELERIRQEERKRELER- 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 855 ilashlCKQKEIEMTQKKMTSEVSVSHEKEKdllhKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLEDIKIANEKNDNLQ 934
Cdd:pfam17380 365 ------IRQEEIAMEISRMRELERLQMERQQ----KNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEARQ 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 935 RMVKLNEETFTKTIFQYtgQLNSLKAENTMLSSKLDNEKQNKERLETDVESfrsrlasalHDHAEIQTAKRDLeiafqra 1014
Cdd:pfam17380 435 REVRRLEEERAREMERV--RLEEQERQQQVERLRQQEEERKRKKLELEKEK---------RDRKRAEEQRRKI------- 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1015 rdewfrvkdkmnfdmsnLRDNNEVLSQQLSKTERKLNSLEIEFhhtkdELREKTLALKHAQRDLSQTQCQMKEVEhmfqd 1094
Cdd:pfam17380 497 -----------------LEKELEERKQAMIEEERKRKLLEKEM-----EERQKAIYEEERRREAEEERRKQQEME----- 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1095 EQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKT-IVNIQDQFQDVLTRFQ-AESQRHSLRLEDRNQE 1172
Cdd:pfam17380 550 ERRRIQEQMRKATEERSRLEAMEREREMMRQIVESEKARAEYEATTpITTIKPIYRPRISEYQpPDVESHMIRFTTQSPE 629
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
1040-1314 |
7.01e-04 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 44.07 E-value: 7.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1040 SQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQgkvskFMGKQESIEERLAQlqSE 1119
Cdd:pfam06160 178 REVLEKLEEETDALEELMEDIPPLYEELKTELPDQLEELKEGYREMEEEGYALEHLN-----VDKEIQQLEEQLEE--NL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1120 NTLLRQQLDDAANKAESKDKTIVNIQDQF-------QDVLTRfQAESQRHSLRLEDRNQELVSECSHLR----------E 1182
Cdd:pfam06160 251 ALLENLELDEAEEALEEIEERIDQLYDLLekevdakKYVEKN-LPEIEDYLEHAEEQNKELKEELERVQqsytlnenelE 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1183 RLCQYENEKAEREVVVRQLQQELADtlKKQSMSEASLEVSSRYRS--NLEEEARDLKKKLGQLRSQLQEARDQhreavhh 1260
Cdd:pfam06160 330 RVRGLEKQLEELEKRYDEIVERLEE--KEVAYSELQEELEEILEQleEIEEEQEEFKESLQSLRKDELEAREK------- 400
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568941650 1261 AEKMEDHLQ--KLELEKSK-------FEITIKKQSEEIDQLQENLSR-----------VNLSEEDKEKLQKLTE 1314
Cdd:pfam06160 401 LDEFKLELReiKRLVEKSNlpglpesYLDYFFDVSDEIEDLADELNEvplnmdevnrlLDEAQDDVDTLYEKTE 474
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
990-1253 |
7.86e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 7.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 990 LASALHDHAEIQTAKRDLEiAFQRARDEWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTL 1069
Cdd:COG4942 12 ALAAAAQADAAAEAEAELE-QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1070 ALKHAQRDLSQTQCQMKevehmfqdEQGKVSKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAeskdktivnIQDQFQ 1149
Cdd:COG4942 91 EIAELRAELEAQKEELA--------ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA---------RREQAE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1150 DvLTRFQAESQRHSLRLEDRNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQsmseaslevssryrSNL 1229
Cdd:COG4942 154 E-LRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAEL--------------AEL 218
|
250 260
....*....|....*....|....
gi 568941650 1230 EEEARDLKKKLGQLRSQLQEARDQ 1253
Cdd:COG4942 219 QQEAEELEALIARLEAEAAAAAER 242
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
1232-1515 |
7.93e-04 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 44.51 E-value: 7.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1232 EARDLKKKLGQLRSQLQEARDQHREAVH---HAEKMEDHLQKLELEKSKFEIT----IKKQSEEIDQLQ-ENLSRVNLSE 1303
Cdd:PLN02939 164 EKEALQGKINILEMRLSETDARIKLAAQekiHVEILEEQLEKLRNELLIRGATeglcVHSLSKELDVLKeENMLLKDDIQ 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1304 EDKEKLQKLTELKESLectvdqeqkrsSALEKELAEFKEVLKmtkkelnEYENRELNLRQDI-KNNHLEMDIpvstLIKK 1382
Cdd:PLN02939 244 FLKAELIEVAETEERV-----------FKLEKERSLLDASLR-------ELESKFIVAQEDVsKLSPLQYDC----WWEK 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1383 IDDLTAKLETASSKCLHlgkknqlLQQELLLMRTIQKKCGKLEKNKKqlEQEVVNLRSHMEKNMvehsqaQQYAREVEER 1462
Cdd:PLN02939 302 VENLQDLLDRATNQVEK-------AALVLDQNQDLRDKVDKLEASLK--EANVSKFSSYKVELL------QQKLKLLEER 366
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 568941650 1463 ARQDLVEKLKQVNLFLQAQAASQESLEQLRENSNasvRSQMELRIKDLESQLY 1515
Cdd:PLN02939 367 LQASDHEIHSYIQLYQESIKEFQDTLSKLKEESK---KRSLEHPADDMPSEFW 416
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1105-1339 |
8.24e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.67 E-value: 8.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1105 KQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQfqdvLTRFQAESQRHSLRLEDRNQELVSECSHLRERL 1184
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAE----LEALQAEIDKLQAEIAEAEAEIEERREELGERA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1185 -CQYENEKAEREVVVRQLQQELADTLKKQSMseasLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAvhhAEK 1263
Cdd:COG3883 93 rALYRSGGSVSYLDVLLGSESFSDFLDRLSA----LSKIADADADLLEELKADKAELEAKKAELEAKLAELEAL---KAE 165
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568941650 1264 MEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRvnLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAE 1339
Cdd:COG3883 166 LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAE--LEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 239
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
783-1275 |
8.80e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.99 E-value: 8.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 783 DQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRtlemELKTVKSHLNQVLEERNETQRQLSREQNARmlqdgilashlcK 862
Cdd:COG4717 49 ERLEKEADELFKPQGRKPELNLKELKELEEELK----EAEEKEEEYAELQEELEELEEELEELEAEL------------E 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 863 QKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKsHNQEKEKRYLEDIKIANEKNDNLQRMVKLNEE 942
Cdd:COG4717 113 ELREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELR-ELEEELEELEAELAELQEELEELLEQLSLATE 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 943 tftKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLASAlHDHAEIQTAKRDLEIAFQRA--RDEWFR 1020
Cdd:COG4717 192 ---EELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAA-ALEERLKEARLLLLIAAALLalLGLGGS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1021 VKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVS 1100
Cdd:COG4717 268 LLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1101 KFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDK--TIVNIQDQFQDVLTRF-QAESQRHSLRLEDRNQELVSEC 1177
Cdd:COG4717 348 ELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEElrAALEQAEEYQELKEELeELEEQLEELLGELEELLEALDE 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1178 SHLRERLCQYENEKAEREVVVRQLQQELADTlkKQSMSEASlevssryrsnLEEEARDLKKKLGQLRSQLQEARDQHREA 1257
Cdd:COG4717 428 EELEEELEELEEELEELEEELEELREELAEL--EAELEQLE----------EDGELAELLQELEELKAELRELAEEWAAL 495
|
490
....*....|....*...
gi 568941650 1258 VHHAEKMEDHLQKLELEK 1275
Cdd:COG4717 496 KLALELLEEAREEYREER 513
|
|
| TMCO5 |
pfam14992 |
TMCO5 family; The TMCO5 family includes human transmembrane and coiled-coil domain-containing ... |
1230-1314 |
1.10e-03 |
|
TMCO5 family; The TMCO5 family includes human transmembrane and coiled-coil domain-containing proteins 5A and 5B.
Pssm-ID: 464427 [Multi-domain] Cd Length: 278 Bit Score: 42.78 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1230 EEEARDLKKKLGQLRSqlqEARDQHREAVHHAE-KMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSR---------- 1298
Cdd:pfam14992 30 EEEIQSLEREITLTRS---LAEDEEREELNFTImEKEDALQELELETAKLEKKNEILVKSVMELQRKLSRksdkntgleq 106
|
90
....*....|....*....
gi 568941650 1299 ---VNLSEEDKEKLQKLTE 1314
Cdd:pfam14992 107 etlKQMLEELKVKLQQSEE 125
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1106-1356 |
1.22e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.57 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1106 QESIEERLAQ---LQSENTLLRQQLDDAANKAESKDKtIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELvsecSHLRE 1182
Cdd:pfam17380 281 QKAVSERQQQekfEKMEQERLRQEKEEKAREVERRRK-LEEAEKARQAEMDRQAAIYAEQERMAMEREREL----ERIRQ 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1183 RLCQYENEKAEREVV------VRQLQQELADTLKKQSMSEASLEVSSRYRsnLEEEARdlKKKLGQLRSQLQEARDQHRE 1256
Cdd:pfam17380 356 EERKRELERIRQEEIameisrMRELERLQMERQQKNERVRQELEAARKVK--ILEEER--QRKIQQQKVEMEQIRAEQEE 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1257 AvhhaekMEDHLQKLELEKSKfeiTIKKQSEEIDQLQENLSRVNLSEEDKEKlQKLTELKESLECTVDQEQKRsSALEKE 1336
Cdd:pfam17380 432 A------RQREVRRLEEERAR---EMERVRLEEQERQQQVERLRQQEEERKR-KKLELEKEKRDRKRAEEQRR-KILEKE 500
|
250 260
....*....|....*....|....*..
gi 568941650 1337 LAEFKEVL-------KMTKKELNEYEN 1356
Cdd:pfam17380 501 LEERKQAMieeerkrKLLEKEMEERQK 527
|
|
| DUF4686 |
pfam15742 |
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ... |
1164-1353 |
1.24e-03 |
|
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.
Pssm-ID: 464838 [Multi-domain] Cd Length: 384 Bit Score: 43.13 E-value: 1.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1164 LRLED-RNQELVSECSHLRERLCQYENEKAEREVVVRQLQQELadtlkKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQ 1242
Cdd:pfam15742 95 LELEVlKQAQSIKSQNSLQEKLAQEKSRVADAEEKILELQQKL-----EHAHKVCLTDTCILEKKQLEERIKEASENEAK 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1243 LRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRV----NLSEEDKEKLQKLTELKES 1318
Cdd:pfam15742 170 LKQQYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLEMTNSQQQLRIQQQEAQLKQLenekRKSDEHLKSNQELSEKLSS 249
|
170 180 190
....*....|....*....|....*....|....*
gi 568941650 1319 LectvdqeQKRSSALEKELAEFKEVLKMTKKELNE 1353
Cdd:pfam15742 250 L-------QQEKEALQEELQQVLKQLDVHVRKYNE 277
|
|
| TRPV1-4 |
cd22193 |
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 1-4; TRPV1-4 are ... |
83-207 |
1.34e-03 |
|
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 1-4; TRPV1-4 are thermo-sensing channels that function directly in temperature-sensing and nociception; they share substantial structural and functional properties. Transient Receptor Potential (TRP) ion channels activated by temperature (thermo TRPs) are important molecular players in acute, inflammatory, and chronic pain states. So far, 11 TRP channels in mammalian cells have been identified as thermosensitive TRP (thermo-TRP) channels. TRPV1-4 channels are activated by different heat temperatures, for example, TRPV1 and TRPV2 are activated by high temperatures (>43C and >55C, respectively). TRPV1-4 belong to the vanilloid TRP subfamily (TRPV), named after the founding member vanilloid receptor 1 (TRPV1). The structure of TRPV shows the typical topology features of all TRP ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains.
Pssm-ID: 411977 [Multi-domain] Cd Length: 607 Bit Score: 43.25 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 83 TALHLACAYGHPEVVTLLVE---RKCEIDARDSESSTALIKAVQCQEeecaailldhgadpnvmDSSGNTALHYAVYSEN 159
Cdd:cd22193 125 LPLSLAACTNQPDIVQYLLEnehQPADIEAQDSRGNTVLHALVTVAD-----------------NTKENTKFVTRMYDMI 187
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 568941650 160 TSMAAKLLAHNANIEAKNKDDLTPMLLAVKENK----QHIVEFLVKKKASIH 207
Cdd:cd22193 188 LIRGAKLCPTVELEEIRNNDGLTPLQLAAKMGKieilKYILQREIKEPELRH 239
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
1033-1364 |
1.41e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 43.29 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1033 RDNNEVLSQQLSKTERKLNSLEiefhhtkDELRekTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEER 1112
Cdd:PRK04778 71 QKWDEIVTNSLPDIEEQLFEAE-------ELND--KFRFRKAKHEINEIESLLDLIEEDIEQILEELQELLESEEKNREE 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1113 LAQL-----QSENTLL--RQQLDDAANKAESKdktIVNIQDQFQDVLTRFQA----ESQRHSLRLEDRNQELvsecSHLR 1181
Cdd:PRK04778 142 VEQLkdlyrELRKSLLanRFSFGPALDELEKQ---LENLEEEFSQFVELTESgdyvEAREILDQLEEELAAL----EQIM 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1182 ERLCQyenekaerevVVRQLQQELADTLKKQSMSEASLEVSSRY--RSNLEEEARDLKKKLGQLRSQLQEAR-DQHREAV 1258
Cdd:PRK04778 215 EEIPE----------LLKELQTELPDQLQELKAGYRELVEEGYHldHLDIEKEIQDLKEQIDENLALLEELDlDEAEEKN 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1259 HHAEKMEDHL-----------QKLELEKSKFEITIKKQSEEIDQLQENLSRVN----LSEEDKEKLQKLTELKESLECTV 1323
Cdd:PRK04778 285 EEIQERIDQLydilerevkarKYVEKNSDTLPDFLEHAKEQNKELKEEIDRVKqsytLNESELESVRQLEKQLESLEKQY 364
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 568941650 1324 DQEQKRS-------SALEKELAEFKEVLKMTKKELNEYENRELNLRQD 1364
Cdd:PRK04778 365 DEITERIaeqeiaySELQEELEEILKQLEEIEKEQEKLSEMLQGLRKD 412
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
1228-1506 |
1.46e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 43.41 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1228 NLEEEARDLKKKLGQLRSQLQEARDQhREAVHHAEKMEDHLQKLELE------KSKFEITIKKQSEEIDQLQ-------- 1293
Cdd:COG5185 279 RLNENANNLIKQFENTKEKIAEYTKS-IDIKKATESLEEQLAAAEAEqeleesKRETETGIQNLTAEIEQGQesltenle 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1294 ---ENLSRVNLSEEDKEKLQKLTELKESLECTVDQ-EQKRSSALEKElaefKEVLKMTKKELNEYENRELNLRQDIKNNH 1369
Cdd:COG5185 358 aikEEIENIVGEVELSKSSEELDSFKDTIESTKESlDEIPQNQRGYA----QEILATLEDTLKAADRQIEELQRQIEQAT 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1370 LEMDIPVSTLIKKIDDLTAKLETASSKclhlgKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEH 1449
Cdd:COG5185 434 SSNEEVSKLLNELISELNKVMREADEE-----SQSRLEEAYDEINRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKL 508
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 568941650 1450 SQAQQYAREVEERARQDLVEKLKQVNLFLQAQAASQESLEQLRENSNASVRSQMELR 1506
Cdd:COG5185 509 ERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNAKTDGQAANL 565
|
|
| NIP100 |
COG5244 |
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle ... |
779-1390 |
1.83e-03 |
|
Dynactin complex subunit involved in mitotic spindle partitioning in anaphase B [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 227569 [Multi-domain] Cd Length: 669 Bit Score: 43.14 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 779 RRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLE--ERNETQRQLSREQNARMLQDGIL 856
Cdd:COG5244 65 RPDDDSLLNGNAAYEKIKGGLVCESKGMDKDGEIKQENHEDRIHFEESKIRRLEEtiEALKSTEKEEIVELRRENEELDK 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 857 ASHLCKQKEIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYLedikiANEKNDNLQRM 936
Cdd:COG5244 145 INLSLRERISSEEPELNKDGSKLSYDELKEFVEESRVQVYDMVELVSDISETLNRNGSIQRSSV-----RECERSNIHDV 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 937 VKLNEETFTKTIFQYTGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSrlasalhdhaeiqtakrdLEIAFQRARD 1016
Cdd:COG5244 220 LFLVNGILDGVIDELNGELERLRRQLVSLMSSHGIEVEENSRLKATLEKFQS------------------LELKVNTLQE 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1017 EWFRVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNS-----LE-IEFHHTKDELREKTLALK------HAQRDLSQTQCQ 1084
Cdd:COG5244 282 ELYQNKLLKKFYQIYEPFAQAALSSQLQYLAEVIESenfgkLEnIEIHIILKVLSSISYALHiytiknTPDHLETTLQCF 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1085 MKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENT------LLRQQLDDAANKAESKDKTIVNIQD------------ 1146
Cdd:COG5244 362 VNIAPISMWLSEFLQRKFSSKQETAFSICQFLEDNKDvtlilkILHPILETTVPKLLAFLRTNSNFNDndtlcligslye 441
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1147 -QFQDVLTRFQAESQRHSlRLEDRNQELVSECSHLR-------ERLCQYeNEKAEREVVVRQLQQELADTLKKQSMSEAS 1218
Cdd:COG5244 442 iARIDKLIGKEEISKQDN-RLFLYPSCDITLSSILTilfsdklEVFFQG-IESLLENITIFPEQPSQQTSDSENIKENSL 519
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1219 LevssryRSNLEEEARDLKKKLGQLRSQLQEardqhreavhhaEKMEDHLQKLELEKSKFEITIKKQSEEIdqlqeNLSR 1298
Cdd:COG5244 520 L------SDRLNEENIRLKEVLVQKENMLTE------------ETKIKIIIGRDLERKTLEENIKTLKVEL-----NNKN 576
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1299 VNLSEEDKEKLQKLTELKESLECTVDQ--EQKRSSALEKELAEFKEVLKMTKKELNEyENRELNLRQDIKNNHLEMDIPV 1376
Cdd:COG5244 577 NKLKEENFNLVNRLKNMELKLYQIKDNntLNKIYLDLVSEIMELRETIRRQIKEQKR-VSIDFSWLDELKQPFKEHIIEM 655
|
650
....*....|....
gi 568941650 1377 STLIKKIDDLTAKL 1390
Cdd:COG5244 656 FNFVSTSRILDLKL 669
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
1041-1205 |
1.98e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.02 E-value: 1.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1041 QQLSKTERKLNSLEIEFHHtKDELREKTLALKHAQRDLSQTQCQMKEV----EHM-FQDEQGKVSKFMGKQESIEERLAQ 1115
Cdd:COG3096 917 KALAQLEPLVAVLQSDPEQ-FEQLQADYLQAKEQQRRLKQQIFALSEVvqrrPHFsYEDAVGLLGENSDLNEKLRARLEQ 995
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1116 LQSENTLLRQQLDDAANKAESKDKTIVNIQDQF---QDVLTRFQAESQRHSLRL--------EDRNQELVSECSHLRERL 1184
Cdd:COG3096 996 AEEARREAREQLRQAQAQYSQYNQVLASLKSSRdakQQTLQELEQELEELGVQAdaeaeeraRIRRDELHEELSQNRSRR 1075
|
170 180
....*....|....*....|.
gi 568941650 1185 CQYENEKAEREVVVRQLQQEL 1205
Cdd:COG3096 1076 SQLEKQLTRCEAEMDSLQKRL 1096
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
716-1318 |
2.36e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 43.12 E-value: 2.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 716 IELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEK---VGWEQELCRLrFALKQEEEKRRSADQLSE----- 787
Cdd:TIGR01612 1171 IEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTSLEEVKginLSYGKNLGKL-FLEKIDEEKKKSEHMIKAmeayi 1249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 788 KTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHlnQVLEERNETQRQLSREQNARMLQDgilashLCKQKEIE 867
Cdd:TIGR01612 1250 EDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDH--HIISKKHDENISDIREKSLKIIED------FSEESDIN 1321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 868 MTQKKMTSEVSVSHEKEKDLlhkNQRLqDEVAVLR--LEMDTIKSHnQEKEKRYLEDIKianEKNDNLQRMVKlNEETFT 945
Cdd:TIGR01612 1322 DIKKELQKNLLDAQKHNSDI---NLYL-NEIANIYniLKLNKIKKI-IDEVKEYTKEIE---ENNKNIKDELD-KSEKLI 1392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 946 KTIfQYTGQLNSLKA--ENTMLSSKLDNEKQNKERLETDVESFRSRLASALHDHAE----IQTAKRDLEIAFQRARDEWF 1019
Cdd:TIGR01612 1393 KKI-KDDINLEECKSkiESTLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADEnnenVLLLFKNIEMADNKSQHILK 1471
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1020 RVKDK----MNFDMSNLRDNNEvlSQQLSKTERKLNSLEIE-----FHHTKDELRE-----KTLALKHaqrDLSQTQcqm 1085
Cdd:TIGR01612 1472 IKKDNatndHDFNINELKEHID--KSKGCKDEADKNAKAIEknkelFEQYKKDVTEllnkySALAIKN---KFAKTK--- 1543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1086 KEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRqqlDDAANKAESkDKTIVNIQDQFQDVLTRFqaesqrhsLR 1165
Cdd:TIGR01612 1544 KDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIE---DDAAKNDKS-NKAAIDIQLSLENFENKF--------LK 1611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1166 LEDRNQELVSecshlrerlCQYENEKAEREVvvrqlqqeladtlkkqsmSEASLEVSSRYRSNLEEEARDLKKKLGQLRS 1245
Cdd:TIGR01612 1612 ISDIKKKIND---------CLKETESIEKKI------------------SSFSIDSQDTELKENGDNLNSLQEFLESLKD 1664
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568941650 1246 QLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIdqlqenlsrvnlSEEDKEKLQKLTELKES 1318
Cdd:TIGR01612 1665 QKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEI------------AIANKEEIESIKELIEP 1725
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
691-1146 |
2.86e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 42.58 E-value: 2.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 691 HLRLECKDTASLLKIRDAVYSYKRLIELKRSHCELLTGKLKRMENKYKglqkEMSETEEVKSRLE-HEKVGWEQELCRLR 769
Cdd:PRK01156 236 NLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHM----KIINDPVYKNRNYiNDYFKYKNDIENKK 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 770 FALKQEEEKRRSADQLSEKTS--EQLRRKGEQCQSEVEARQQLEASLRTLEME----LKTVKShLNQVLEERNETQRQLS 843
Cdd:PRK01156 312 QILSNIDAEINKYHAIIKKLSvlQKDYNDYIKKKSRYDDLNNQILELEGYEMDynsyLKSIES-LKKKIEEYSKNIERMS 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 844 REQNARMLQDGILASHLCKQK-EIEMTQKKMTSEVSVSHEKEKDLLHKNQRLQDEVAVLRLE--------------MDTI 908
Cdd:PRK01156 391 AFISEILKIQEIDPDAIKKELnEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQsvcpvcgttlgeekSNHI 470
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 909 KSHNQEKEKRYLEDI--------KIANEKNDNLQRMVKLNEETFTKTIFQYTgQLNSLKAENTMLSSKLDNEKQNKERLE 980
Cdd:PRK01156 471 INHYNEKKSRLEEKIreieievkDIDEKIVDLKKRKEYLESEEINKSINEYN-KIESARADLEDIKIKINELKDKHDKYE 549
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 981 TDVESFRSRlasalhdhaeiqtakrDLEIAFQRaRDEWFRVKDKM-NFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHH 1059
Cdd:PRK01156 550 EIKNRYKSL----------------KLEDLDSK-RTSWLNALAVIsLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPD 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1060 TKD-------ELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQ---QLDD 1129
Cdd:PRK01156 613 DKSyidksirEIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKsrkALDD 692
|
490
....*....|....*...
gi 568941650 1130 A-ANKAESKDKTIVNIQD 1146
Cdd:PRK01156 693 AkANRARLESTIEILRTR 710
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1231-1472 |
3.39e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 3.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1231 EEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKlq 1310
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA-- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1311 KLTELKESLECTVDQEQKRSSALEKEL----AEFKEVLKMTK--KELNEYENRELN-LRQDIKNnhlemdipVSTLIKKI 1383
Cdd:COG4942 98 ELEAQKEELAELLRALYRLGRQPPLALllspEDFLDAVRRLQylKYLAPARREQAEeLRADLAE--------LAALRAEL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1384 DDLTAKLETAsskclhLGKKNQLLQQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEERA 1463
Cdd:COG4942 170 EAERAELEAL------LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
....*....
gi 568941650 1464 RQDLVEKLK 1472
Cdd:COG4942 244 PAAGFAALK 252
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1031-1558 |
3.49e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 42.31 E-value: 3.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1031 NLRDNNEVLSQQLSKterKLNSLEIEFHHTKDELR--EKTLALKHAQRDLSQTQcqMKEVEHMFQDEQGKVSKFMGKQES 1108
Cdd:TIGR04523 26 NIANKQDTEEKQLEK---KLKTIKNELKNKEKELKnlDKNLNKDEEKINNSNNK--IKILEQQIKDLNDKLKKNKDKINK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1109 IEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFqaesqrhsLRLEDRNQELVSECSHLRERLCQYE 1188
Cdd:TIGR04523 101 LNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEI--------KKKEKELEKLNNKYNDLKKQKEELE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1189 NEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRY-----------------RSNLEEEARDLKKKLGQLRSQLQEAR 1251
Cdd:TIGR04523 173 NELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKiqknkslesqiselkkqNNQLKDNIEKKQQEINEKTTEISNTQ 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1252 DQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRVNlSEEDKEKLQKLTELKESLECTVDQEQKRSS 1331
Cdd:TIGR04523 253 TQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN-NQKEQDWNKELKSELKNQEKKLEEIQNQIS 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1332 ALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEmdipVSTLIKKIDDLTAKLETASSKCLHLGKKNQLLQQEL 1411
Cdd:TIGR04523 332 QNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNE----IEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLN 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1412 LLmrtIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHS--QAQQYAREVE----ERARQDLVEKLKQVNLFLQAQAASQ 1485
Cdd:TIGR04523 408 QQ---KDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKdlTNQDSVKELIiknlDNTRESLETQLKVLSRSINKIKQNL 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1486 ESLEQLRENSNA------SVRSQMELRIKDLESQLYRMKA-QEDFDKIELEKYKQLYQEEfraRKSLSSKLNKTSEKLEE 1558
Cdd:TIGR04523 485 EQKQKELKSKEKelkklnEEKKELEEKVKDLTKKISSLKEkIEKLESEKKEKESKISDLE---DELNKDDFELKKENLEK 561
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
1211-1342 |
3.69e-03 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 42.12 E-value: 3.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1211 KQSMSEASLEVSsRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAEKMEDHLQKLELE-KSKFEITIKKQSEEI 1289
Cdd:PRK00409 508 KKLIGEDKEKLN-ELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEaEKEAQQAIKEAKKEA 586
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 568941650 1290 DQLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKELAEFKE 1342
Cdd:PRK00409 587 DEIIKELRQLQKGGYASVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELKV 639
|
|
| ANK |
smart00248 |
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
147-175 |
3.73e-03 |
|
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.
Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 36.41 E-value: 3.73e-03
10 20
....*....|....*....|....*....
gi 568941650 147 GNTALHYAVYSENTSMAAKLLAHNANIEA 175
Cdd:smart00248 2 GRTPLHLAAENGNLEVVKLLLDKGADINA 30
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
1194-1567 |
4.19e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 41.81 E-value: 4.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1194 REVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQ--LRSQLQEARDQHREAVHHAEKMEDHLQKL 1271
Cdd:PLN02939 40 RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQksTSSDDDHNRASMQRDEAIAAIDNEQQTNS 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1272 ELEKSKFEITIKKQSEEIDQLQENLSRVNLSE----EDKEKLqkLTElKESLectvdqeQKRSSALEKELAEFKEVLKMT 1347
Cdd:PLN02939 120 KDGEQLSDFQLEDLVGMIQNAEKNILLLNQARlqalEDLEKI--LTE-KEAL-------QGKINILEMRLSETDARIKLA 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1348 KKELNEYENRE---LNLRQDIKNNHLEMDIPVSTLIKKIDDLtaKLETASSK--CLHLGKKNQLLQQELLLMRTIQKKCG 1422
Cdd:PLN02939 190 AQEKIHVEILEeqlEKLRNELLIRGATEGLCVHSLSKELDVL--KEENMLLKddIQFLKAELIEVAETEERVFKLEKERS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1423 KLEKNKKQLEQEVVNLRSHMEKnmVEHSQAQQYAREVEERarQDLVEKLK----QVNLFLQAQAASQESLEQLRENSNAS 1498
Cdd:PLN02939 268 LLDASLRELESKFIVAQEDVSK--LSPLQYDCWWEKVENL--QDLLDRATnqveKAALVLDQNQDLRDKVDKLEASLKEA 343
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568941650 1499 VRSQMELRIKDLESQlyRMKA-QEDFDKI--ELEKYKQLYQEefrarksLSSKLNKTSEKLEEASSKLLLEE 1567
Cdd:PLN02939 344 NVSKFSSYKVELLQQ--KLKLlEERLQASdhEIHSYIQLYQE-------SIKEFQDTLSKLKEESKKRSLEH 406
|
|
| PHA02736 |
PHA02736 |
Viral ankyrin protein; Provisional |
132-204 |
4.53e-03 |
|
Viral ankyrin protein; Provisional
Pssm-ID: 165103 [Multi-domain] Cd Length: 154 Bit Score: 39.47 E-value: 4.53e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568941650 132 ILLDHGADPNVMDS-SGNTALHYAVYSENTSMAAKLLAH-NANIEAKNKDDLTPMLLAVKENKQHIVEFLVKKKA 204
Cdd:PHA02736 76 LLMEWGADINGKERvFGNTPLHIAVYTQNYELATWLCNQpGVNMEILNYAFKTPYYVACERHDAKMMNILRAKGA 150
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
689-949 |
5.63e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.50 E-value: 5.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 689 IEHLRLECKDTASLLKIRDAVYSYKRLIELKRSHCELLTGKLKRMENKYKGLQKEMSETEEVKSRLEHEKvgwEQELCRL 768
Cdd:pfam02463 755 SRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLI---EQEEKIK 831
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 769 RFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEVEARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSR---E 845
Cdd:pfam02463 832 EEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQklnL 911
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 846 QNARMLQDGILASHLCKQKEIEMTQKKMTS-----EVSVSHEKEKDLLHKNQRLQDEVAVLRLEMDTIKSHNQEKEKRYL 920
Cdd:pfam02463 912 LEEKENEIEERIKEEAEILLKYEEEPEELLleeadEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYN 991
|
250 260 270
....*....|....*....|....*....|...
gi 568941650 921 ED----IKIANEKNDNLQRMVKLNEETFTKTIF 949
Cdd:pfam02463 992 KDelekERLEEEKKKLIRAIIEETCQRLKEFLE 1024
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1171-1466 |
5.93e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.04 E-value: 5.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1171 QELVSECSHLRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEA 1250
Cdd:COG4372 41 DKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEEL 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1251 RDQHREAVHHAEKMEDHLQKLELEKSKFEITIKKQSEEIDQLQENLSRV---NLSEEDKEKLQKLTELKESLECTVDQEQ 1327
Cdd:COG4372 121 QKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALeqeLQALSEAEAEQALDELLKEANRNAEKEE 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1328 KRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEMDIPVSTLIKKIDDLTAKLETASSKCLHLGKKNQLL 1407
Cdd:COG4372 201 ELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEI 280
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 568941650 1408 QQELLLMRTIQKKCGKLEKNKKQLEQEVVNLRSHMEKNMVEHSQAQQYAREVEERARQD 1466
Cdd:COG4372 281 AALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAEL 339
|
|
| RecN |
COG0497 |
DNA repair ATPase RecN [Replication, recombination and repair]; |
1106-1287 |
6.31e-03 |
|
DNA repair ATPase RecN [Replication, recombination and repair];
Pssm-ID: 440263 [Multi-domain] Cd Length: 555 Bit Score: 41.21 E-value: 6.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1106 QESIEERLAQLQSENTLLRQQLDDAANKAESkdktIVNIQDQFQDVLTRFQ-AESQrhslrLEDRNQELVSECSHLR--- 1181
Cdd:COG0497 225 REALQEALEALSGGEGGALDLLGQALRALER----LAEYDPSLAELAERLEsALIE-----LEEAASELRRYLDSLEfdp 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1182 ERLcqyeNEKAEREVVVRQLQQ----------ELADTLKKQSmseASLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEAR 1251
Cdd:COG0497 296 ERL----EEVEERLALLRRLARkygvtveellAYAEELRAEL---AELENSDERLEELEAELAEAEAELLEAAEKLSAAR 368
|
170 180 190
....*....|....*....|....*....|....*..
gi 568941650 1252 dqhREAVHH-AEKMEDHLQKLELEKSKFEITIKKQSE 1287
Cdd:COG0497 369 ---KKAAKKlEKAVTAELADLGMPNARFEVEVTPLEE 402
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
1110-1437 |
6.65e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 41.48 E-value: 6.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1110 EERLAQlqsentlLRQQLDDAANKAESKDKTIVNIQDQFQDvLTRFQAESQRHSLRlEDRNQELVSecshLRERLCQYEN 1189
Cdd:PRK04863 785 EKRIEQ-------LRAEREELAERYATLSFDVQKLQRLHQA-FSRFIGSHLAVAFE-ADPEAELRQ----LNRRRVELER 851
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1190 EKAEREVVVRQLQQELaDTLKKQSMSEASLEVSSryrSNLEEEarDLKKKLGQLRSQLQEARDQHREAVHH---AEKMED 1266
Cdd:PRK04863 852 ALADHESQEQQQRSQL-EQAKEGLSALNRLLPRL---NLLADE--TLADRVEEIREQLDEAEEAKRFVQQHgnaLAQLEP 925
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1267 HLQKLELEKSKFEiTIKKQSEEIDQLQENLS------------RVNLSEEDKEK-LQKLTELKESLectvdqeQKRSSAL 1333
Cdd:PRK04863 926 IVSVLQSDPEQFE-QLKQDYQQAQQTQRDAKqqafaltevvqrRAHFSYEDAAEmLAKNSDLNEKL-------RQRLEQA 997
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1334 EKELAEFKEVLKMTKKELNEYENRELNL----------RQDIKNNHLEMDIPVST-----LIKKIDDLTAKLETASSKCL 1398
Cdd:PRK04863 998 EQERTRAREQLRQAQAQLAQYNQVLASLkssydakrqmLQELKQELQDLGVPADSgaeerARARRDELHARLSANRSRRN 1077
|
330 340 350
....*....|....*....|....*....|....*....
gi 568941650 1399 HLGKKnqlLQQELLLMRTIQKKCGKLEKNKKQLEQEVVN 1437
Cdd:PRK04863 1078 QLEKQ---LTFCEAEMDNLTKKLRKLERDYHEMREQVVN 1113
|
|
| PHA02946 |
PHA02946 |
ankyin-like protein; Provisional |
133-213 |
7.22e-03 |
|
ankyin-like protein; Provisional
Pssm-ID: 165256 [Multi-domain] Cd Length: 446 Bit Score: 40.81 E-value: 7.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 133 LLDHGADPNVMDSSGNTALHYAVYSENTSMAAKLLAHNANIEAKNKDDLTPMLLAVKENKQHI--VEFLVKKKASI-HAV 209
Cdd:PHA02946 58 LLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLYYLSGTDDEVIerINLLVQYGAKInNSV 137
|
....
gi 568941650 210 DQLG 213
Cdd:PHA02946 138 DEEG 141
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
886-1391 |
7.84e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 41.04 E-value: 7.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 886 DLLHKNQRLQDEVAVLRLEMD---TIKSHNQEKEKRYLEDIKIANEKNDN----LQRMVKLNEET--FTKTIFQYTGQLN 956
Cdd:PRK01156 187 YLEEKLKSSNLELENIKKQIAddeKSHSITLKEIERLSIEYNNAMDDYNNlksaLNELSSLEDMKnrYESEIKTAESDLS 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 957 SLKAENTMLSS------KLDNEKQNKER--------LETDVESFRSRLASALHDHAEIQTAKRDLEIaFQRARDEWF--- 1019
Cdd:PRK01156 267 MELEKNNYYKEleerhmKIINDPVYKNRnyindyfkYKNDIENKKQILSNIDAEINKYHAIIKKLSV-LQKDYNDYIkkk 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1020 RVKDKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKV 1099
Cdd:PRK01156 346 SRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKV 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1100 SKFMGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVsecsH 1179
Cdd:PRK01156 426 SSLNQRIRALRENLDELSRNMEMLNGQSVCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIV----D 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1180 LRERLCQYENEKAEREVVVRQLQQELADTLKKQSMSEASL--------EVSSRYRS----NLEEEARDLKKKLGQLRS-Q 1246
Cdd:PRK01156 502 LKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINELkdkhdkyeEIKNRYKSlkleDLDSKRTSWLNALAVISLiD 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1247 LQEARDQHREAVHHAEKMEDHLQKLELE----KSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLECT 1322
Cdd:PRK01156 582 IETNRSRSNEIKKQLNDLESRLQEIEIGfpddKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAE 661
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 568941650 1323 VDQEQKRSSALEKELAEFKEVLKMTKKELNEYENRELNLRQDIKNNHLEmdipVSTLIKKIDDLTAKLE 1391
Cdd:PRK01156 662 IDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTR----INELSDRINDINETLE 726
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
926-1352 |
8.09e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.09 E-value: 8.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 926 ANEKNDNLQRMVKLNEETFTKTifqytGQLNSLKAENTMLSSKLDNEKQNKERLETDVESFRSRLAsalhdhaEIQTAKR 1005
Cdd:COG3096 277 ANERRELSERALELRRELFGAR-----RQLAEEQYRLVEMARELEELSARESDLEQDYQAASDHLN-------LVQTALR 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1006 DLEiAFQRARDewfrvkdkmnfDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQR--DLSQT-- 1081
Cdd:COG3096 345 QQE-KIERYQE-----------DLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQalDVQQTra 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1082 -QCQ-----MKEVEHMFQDEQGKVSKFMGKQESIEERLAQLQSENTLLRQQL---DDAANKAESKDKTIVNIQDQfqdvL 1152
Cdd:COG3096 413 iQYQqavqaLEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLsvaDAARRQFEKAYELVCKIAGE----V 488
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1153 TRFQAESQRHSLRLEDRNQELVSE-CSHLRERLCQYENEKAEREVVVRQLQ---QELADTLKKQSMSEASLEVSSRYRSN 1228
Cdd:COG3096 489 ERSQAWQTARELLRRYRSQQALAQrLQQLRAQLAELEQRLRQQQNAERLLEefcQRIGQQLDAAEELEELLAELEAQLEE 568
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1229 LEEEARDLKKKLGQLRSQLQEARDQHREavhhaekmedhlqklelekskfeitIKKQSEEIDQLQENLSRvnLSEEDKEK 1308
Cdd:COG3096 569 LEEQAAEAVEQRSELRQQLEQLRARIKE-------------------------LAARAPAWLAAQDALER--LREQSGEA 621
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 568941650 1309 LQKLTELKESLECTVDQEQKRsSALEKELAEFKEVLKMTKKELN 1352
Cdd:COG3096 622 LADSQEVTAAMQQLLEREREA-TVERDELAARKQALESQIERLS 664
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
692-852 |
8.59e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.91 E-value: 8.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 692 LRLECKDTASLLKIRDAVYSYKRLIELKRSHCELLTGKLKRMEnKYKGLQKEMSETEEVKSRLEHEKVGWE---QELCRL 768
Cdd:COG4717 80 LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE-KLLQLLPLYQELEALEAELAELPERLEeleERLEEL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 769 RFALKQEEEKRRSADQLSEKTSEQLRRKGEQCQSEV----EARQQLEASLRTLEMELKTVKSHLNQVLEERNETQRQLSR 844
Cdd:COG4717 159 RELEEELEELEAELAELQEELEELLEQLSLATEEELqdlaEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEA 238
|
....*...
gi 568941650 845 EQNARMLQ 852
Cdd:COG4717 239 AALEERLK 246
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1023-1353 |
9.14e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 40.27 E-value: 9.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1023 DKMNFDMSNLRDNNEVLSQQLSKTERKLNSLEIEFHHTKDELREKTLALKHAQRDLSQTQCQMKEVEHMFQDEQGKVSKF 1102
Cdd:COG4372 34 RKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEEL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1103 MGKQESIEERLAQLQSENTLLRQQLDDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLRLEDRNQELVSECSHLRE 1182
Cdd:COG4372 114 QEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEAN 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1183 RLCQYENEKAEREVVVRQLQQELADTLKKQSMSEaSLEVSSRYRSNLEEEARDLKKKLGQLRSQLQEARDQHREAVHHAE 1262
Cdd:COG4372 194 RNAEKEEELAEAEKLIESLPRELAEELLEAKDSL-EAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKD 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1263 KMEDHLQKLELEKSKFEITIKKQSEE-----IDQLQENLSRVNLSEEDKEKLQKLTELKESLECTVDQEQKRSSALEKEL 1337
Cdd:COG4372 273 TEEEELEIAALELEALEEAALELKLLalllnLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLD 352
|
330
....*....|....*.
gi 568941650 1338 AEFKEVLKMTKKELNE 1353
Cdd:COG4372 353 NDVLELLSKGAEAGVA 368
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
1035-1340 |
9.62e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 40.83 E-value: 9.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1035 NNEVLSQQLSKTERKLNSLEIEfhhTKDELREKTLA-LKHAQRDLSQTQCQMKEVEHMFQdeqgkvsKFMGKQESIEERL 1113
Cdd:COG5022 843 KAEVLIQKFGRSLKAKKRFSLL---KKETIYLQSAQrVELAERQLQELKIDVKSISSLKL-------VNLELESEIIELK 912
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1114 AQLQSentllrqqldDAANKAESKDKTIVNIQDQFQDVLTRFQAESQRHSLrleDRNQELVSECSHLRERLCQYENEKAE 1193
Cdd:COG5022 913 KSLSS----------DLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKL---PELNKLHEVESKLKETSEEYEDLLKK 979
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1194 REVVVRQLQQELADTLK-KQSMSEASLEvssryRSNLEEEARDLKKKLGQLRSQLQearDQHREAVHHAEKmedhLQKLE 1272
Cdd:COG5022 980 STILVREGNKANSELKNfKKELAELSKQ-----YGALQESTKQLKELPVEVAELQS---ASKIISSESTEL----SILKP 1047
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568941650 1273 LEKSKFEITIKKQSEEIDQLQENLSRVNLSEEDKEKLQKLTELKESLECTVD--QEQKRSSALEKELAEF 1340
Cdd:COG5022 1048 LQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINVKdlEVTNRNLVKPANVLQF 1117
|
|
| |
