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Conserved domains on  [gi|568939720|ref|XP_006505197|]
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kielin/chordin-like protein isoform X7 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 166-220 5.05e-07

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member pfam00093:

Pssm-ID: 450195  Cd Length: 57  Bit Score: 47.42  E-value: 5.05e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 568939720  166 CSHNGQSYGHGETFSPDACTTCRCLAGTVQCQGPSCSELNCLESF--IPPGECCPIC 220
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRleIPPGECCPVC 57
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 458-514 7.70e-05

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member pfam00093:

Pssm-ID: 450195  Cd Length: 57  Bit Score: 41.26  E-value: 7.70e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568939720  458 CVLNGEEFAEGIQWEPDdqPCTSCSCQDGVPVCRAVLCSPVPCQHPT--QPPGACCPSC 514
Cdd:pfam00093   1 CVQNGVVYENGETWKPD--LCTICTCDDGKVLCDKIICPPLDCPNPRleIPPGECCPVC 57
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 344-399 1.06e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member pfam00093:

Pssm-ID: 450195  Cd Length: 57  Bit Score: 40.87  E-value: 1.06e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568939720  344 CFLNGREHSSGEPVGSqDPCSSCRCTNGSVQCEPLPCPPAPCRYPGRI--PGQCCPVC 399
Cdd:pfam00093   1 CVQNGVVYENGETWKP-DLCTICTCDDGKVLCDKIICPPLDCPNPRLEipPGECCPVC 57
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 634-690 1.63e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member pfam00093:

Pssm-ID: 450195  Cd Length: 57  Bit Score: 40.10  E-value: 1.63e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568939720  634 CAFGGKEYPNGADFpHPtDPCRLCRCLSGNVQCLARRCPPLSCPQPVLT--PGDCCPQC 690
Cdd:pfam00093   1 CVQNGVVYENGETW-KP-DLCTICTCDDGKVLCDKIICPPLDCPNPRLEipPGECCPVC 57
VWC super family cl17735
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 224-280 1.56e-03

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


The actual alignment was detected with superfamily member pfam00093:

Pssm-ID: 450195  Cd Length: 57  Bit Score: 37.40  E-value: 1.56e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568939720  224 CEYEGQLHQEGSSFLSSsnPCLQCSCLRSLVRCVPVKCQPSPCLNP--VPRLGHCCPVC 280
Cdd:pfam00093   1 CVQNGVVYENGETWKPD--LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
 
Name Accession Description Interval E-value
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 166-220 5.05e-07

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 47.42  E-value: 5.05e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 568939720  166 CSHNGQSYGHGETFSPDACTTCRCLAGTVQCQGPSCSELNCLESF--IPPGECCPIC 220
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRleIPPGECCPVC 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 458-514 7.70e-05

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 41.26  E-value: 7.70e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568939720  458 CVLNGEEFAEGIQWEPDdqPCTSCSCQDGVPVCRAVLCSPVPCQHPT--QPPGACCPSC 514
Cdd:pfam00093   1 CVQNGVVYENGETWKPD--LCTICTCDDGKVLCDKIICPPLDCPNPRleIPPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
166-220 8.98e-05

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 40.96  E-value: 8.98e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 568939720   166 CSHNGQSYGHGETFSPDACTTCRCLAG-TVQCQGPSC-SELNCL--ESFIPPGECCPIC 220
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGtTVLCDPVECpPPPDCPnpERVKPPGECCPRC 59
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 344-399 1.06e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 40.87  E-value: 1.06e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568939720  344 CFLNGREHSSGEPVGSqDPCSSCRCTNGSVQCEPLPCPPAPCRYPGRI--PGQCCPVC 399
Cdd:pfam00093   1 CVQNGVVYENGETWKP-DLCTICTCDDGKVLCDKIICPPLDCPNPRLEipPGECCPVC 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 634-690 1.63e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 40.10  E-value: 1.63e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568939720  634 CAFGGKEYPNGADFpHPtDPCRLCRCLSGNVQCLARRCPPLSCPQPVLT--PGDCCPQC 690
Cdd:pfam00093   1 CVQNGVVYENGETW-KP-DLCTICTCDDGKVLCDKIICPPLDCPNPRLEipPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
458-514 3.32e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 39.42  E-value: 3.32e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568939720   458 CVLNGEEFAEGIQWEPDdqPCTSCSCQDGVPV-CRAVLCSPVP-CQHPT--QPPGACCPSC 514
Cdd:smart00214   1 CVHNGRVYNDGETWKPD--PCQICTCLDGTTVlCDPVECPPPPdCPNPErvKPPGECCPRC 59
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 224-280 1.56e-03

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 37.40  E-value: 1.56e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568939720  224 CEYEGQLHQEGSSFLSSsnPCLQCSCLRSLVRCVPVKCQPSPCLNP--VPRLGHCCPVC 280
Cdd:pfam00093   1 CVQNGVVYENGETWKPD--LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
344-399 1.72e-03

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 37.50  E-value: 1.72e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568939720   344 CFLNGREHSSGEpVGSQDPCSSCRCTNGS-VQCEPLPCPPAP-CRYPGRI--PGQCCPVC 399
Cdd:smart00214   1 CVHNGRVYNDGE-TWKPDPCQICTCLDGTtVLCDPVECPPPPdCPNPERVkpPGECCPRC 59
 
Name Accession Description Interval E-value
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 166-220 5.05e-07

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 47.42  E-value: 5.05e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 568939720  166 CSHNGQSYGHGETFSPDACTTCRCLAGTVQCQGPSCSELNCLESF--IPPGECCPIC 220
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRleIPPGECCPVC 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 458-514 7.70e-05

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 41.26  E-value: 7.70e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568939720  458 CVLNGEEFAEGIQWEPDdqPCTSCSCQDGVPVCRAVLCSPVPCQHPT--QPPGACCPSC 514
Cdd:pfam00093   1 CVQNGVVYENGETWKPD--LCTICTCDDGKVLCDKIICPPLDCPNPRleIPPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
166-220 8.98e-05

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 40.96  E-value: 8.98e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 568939720   166 CSHNGQSYGHGETFSPDACTTCRCLAG-TVQCQGPSC-SELNCL--ESFIPPGECCPIC 220
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGtTVLCDPVECpPPPDCPnpERVKPPGECCPRC 59
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 344-399 1.06e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 40.87  E-value: 1.06e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 568939720  344 CFLNGREHSSGEPVGSqDPCSSCRCTNGSVQCEPLPCPPAPCRYPGRI--PGQCCPVC 399
Cdd:pfam00093   1 CVQNGVVYENGETWKP-DLCTICTCDDGKVLCDKIICPPLDCPNPRLEipPGECCPVC 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 634-690 1.63e-04

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 40.10  E-value: 1.63e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568939720  634 CAFGGKEYPNGADFpHPtDPCRLCRCLSGNVQCLARRCPPLSCPQPVLT--PGDCCPQC 690
Cdd:pfam00093   1 CVQNGVVYENGETW-KP-DLCTICTCDDGKVLCDKIICPPLDCPNPRLEipPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
458-514 3.32e-04

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 39.42  E-value: 3.32e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568939720   458 CVLNGEEFAEGIQWEPDdqPCTSCSCQDGVPV-CRAVLCSPVP-CQHPT--QPPGACCPSC 514
Cdd:smart00214   1 CVHNGRVYNDGETWKPD--PCQICTCLDGTTVlCDPVECPPPPdCPNPErvKPPGECCPRC 59
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 224-280 1.56e-03

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 37.40  E-value: 1.56e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 568939720  224 CEYEGQLHQEGSSFLSSsnPCLQCSCLRSLVRCVPVKCQPSPCLNP--VPRLGHCCPVC 280
Cdd:pfam00093   1 CVQNGVVYENGETWKPD--LCTICTCDDGKVLCDKIICPPLDCPNPrlEIPPGECCPVC 57
VWC smart00214
von Willebrand factor (vWF) type C domain;
344-399 1.72e-03

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 37.50  E-value: 1.72e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568939720   344 CFLNGREHSSGEpVGSQDPCSSCRCTNGS-VQCEPLPCPPAP-CRYPGRI--PGQCCPVC 399
Cdd:smart00214   1 CVHNGRVYNDGE-TWKPDPCQICTCLDGTtVLCDPVECPPPPdCPNPERVkpPGECCPRC 59
Amnionless pfam14828
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ...
 478-514 3.80e-03

Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.


Pssm-ID: 464340  Cd Length: 449  Bit Score: 40.45  E-value: 3.80e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 568939720  478 CTSCSCQDGV---PVCRAVL--CSPVPCQHPTQPPGACCPSC 514
Cdd:pfam14828 194 PSGCGCGNDEnleRICANVLqrCPPPHCLSPLRPEGHCCDVC 235
Amnionless pfam14828
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ...
 351-399 4.25e-03

Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.


Pssm-ID: 464340  Cd Length: 449  Bit Score: 40.45  E-value: 4.25e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 568939720  351 HSSGEPVGSQDPC---SSCRCTNGSVQ---CEPLP--CPPAPCRYPGRIPGQCCPVC 399
Cdd:pfam14828 179 HGAGALRVGPEACsdpSGCGCGNDENLeriCANVLqrCPPPHCLSPLRPEGHCCDVC 235
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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