|
Name |
Accession |
Description |
Interval |
E-value |
| BAH_BAHCC1 |
cd04714 |
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. ... |
2798-2942 |
5.03e-57 |
|
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.
:
Pssm-ID: 240065 Cd Length: 121 Bit Score: 193.77 E-value: 5.03e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2798 KEMIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKqfhegqhwdqksghslpaalrassqR 2877
Cdd:cd04714 1 KEIIRVGDCVLFKSPGRPSLPYVARIESLWEDPEGNMVVRVKWYYRPEETKGGR-------------------------K 55
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568938691 2878 KDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLK-TKKYQDSEGLYYLAGTYEPTTGMIFS 2942
Cdd:cd04714 56 PNHGEKELFASDHQDENSVQTIEHKCYVLTFAEYERLARvKKKPQDGVDFYYCAGTYNPDTGMLKC 121
|
|
| Tudor_SF super family |
cl02573 |
Tudor domain superfamily; The Tudor domain is a conserved structural domain, originally ... |
2203-2269 |
9.72e-37 |
|
Tudor domain superfamily; The Tudor domain is a conserved structural domain, originally identified in the Tudor protein of Drosophila, that adopts a beta-barrel-like core structure containing four short beta-strands followed by an alpha-helical region. It binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions. Tudor domain-containing proteins may mediate protein-protein interactions required for various DNA-templated biological processes, such as RNA metabolism, as well as histone modification and the DNA damage response. Members of this superfamily contain one or more copies of the Tudor domain.
The actual alignment was detected with superfamily member cd20469:
Pssm-ID: 470623 Cd Length: 67 Bit Score: 133.70 E-value: 9.72e-37
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568938691 2203 STRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKI 2269
Cdd:cd20469 1 SVRFLPEGTRVCAYWSQQYRCLYPGTVVKGSPDPEEDDDLITVEFDDGDSGRIPLDHIRLLPPDYPI 67
|
|
| PRK12323 super family |
cl46901 |
DNA polymerase III subunit gamma/tau; |
2264-2478 |
1.34e-03 |
|
DNA polymerase III subunit gamma/tau;
The actual alignment was detected with superfamily member PRK12323:
Pssm-ID: 481241 [Multi-domain] Cd Length: 700 Bit Score: 44.48 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2264 PPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEVKEGAATGPQEATGGKARgrgRKPSTKA-KADRAVVLEEGAATNEVP 2342
Cdd:PRK12323 375 ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPAR---RSPAPEAlAAARQASARGPGGAPAPA 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2343 SAPLALEPISTPNSKKSTPEPVDKRARAPKARSISAQPSPVP---PTFSSCPA--PEPFGELPTPATAPLVTMPVTMPAT 2417
Cdd:PRK12323 452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADddpPPWEELPPefASPAPAQPDAAPAGWVAESIPDPAT 531
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568938691 2418 RPKPKKARAAEGSGAKGPRRPgeddellVKLDHEGVMSPKSKKAKEALLlrEDPGPGGWPE 2478
Cdd:PRK12323 532 ADPDDAFETLAPAPAAAPAPR-------AAAATEPVVAPRPPRASASGL--PDMFDGDWPA 583
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
1048-1357 |
9.85e-03 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 9.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1048 PFQALFTDIPPRYPFQALPPhyGRPYPFLLQPAAASDADglAPDVPLPADGPERLALSPEDKPICLSPSkiPEPPRDSPE 1127
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPP--PRPAPRPSEPAVTSRAR--RPDAPPQSARPRAPVDDRGDPRGPAPPS--PLPPDTHAP 2624
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1128 EEQLADREVKAEvEDIEEGPTELPPLESPLALPVPeTMVAVSPAGGCGGSPLEAQAlSTAGPGCRE-PSEVSDFAQVAEP 1206
Cdd:PHA03247 2625 DPPPPSPSPAAN-EPDPHPPPTVPPPERPRDDPAP-GRVSRPRRARRLGRAAQASS-PPQRPRRRAaRPTVGSLTSLADP 2701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1207 QIElPSKTEHRMTALELGTQLTPEPLVETKEEPVEVPLDVPMEEPTTEAGPED-----------------------SLPQ 1263
Cdd:PHA03247 2702 PPP-PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGparparppttagppapappaapaAGPP 2780
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1264 PSLTEPQ-PSLELSDCDLPVPEgqclnleAQEAVPAPASTCYLEETHSESLLPGLDDPLAGMNALAAAAELPQARPLPSL 1342
Cdd:PHA03247 2781 RRLTRPAvASLSESRESLPSPW-------DPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853
|
330
....*....|....*
gi 568938691 1343 GPGVPAGEKLDTAPS 1357
Cdd:PHA03247 2854 GSVAPGGDVRRRPPS 2868
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| BAH_BAHCC1 |
cd04714 |
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. ... |
2798-2942 |
5.03e-57 |
|
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.
Pssm-ID: 240065 Cd Length: 121 Bit Score: 193.77 E-value: 5.03e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2798 KEMIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKqfhegqhwdqksghslpaalrassqR 2877
Cdd:cd04714 1 KEIIRVGDCVLFKSPGRPSLPYVARIESLWEDPEGNMVVRVKWYYRPEETKGGR-------------------------K 55
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568938691 2878 KDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLK-TKKYQDSEGLYYLAGTYEPTTGMIFS 2942
Cdd:cd04714 56 PNHGEKELFASDHQDENSVQTIEHKCYVLTFAEYERLARvKKKPQDGVDFYYCAGTYNPDTGMLKC 121
|
|
| Tudor_TNRC18 |
cd20469 |
Tudor domain found in trinucleotide repeat-containing gene 18 protein (TNRC18) and similar ... |
2203-2269 |
9.72e-37 |
|
Tudor domain found in trinucleotide repeat-containing gene 18 protein (TNRC18) and similar proteins; TNRC18, also called long CAG trinucleotide repeat-containing gene 79 protein (CAGL79), is a protein that in humans is encoded by the TNRC18 gene. Its biological function remains unclear. TNRC18 contains one Tudor domain. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
Pssm-ID: 410540 Cd Length: 67 Bit Score: 133.70 E-value: 9.72e-37
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568938691 2203 STRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKI 2269
Cdd:cd20469 1 SVRFLPEGTRVCAYWSQQYRCLYPGTVVKGSPDPEEDDDLITVEFDDGDSGRIPLDHIRLLPPDYPI 67
|
|
| BAH |
smart00439 |
Bromo adjacent homology domain; |
2800-2938 |
1.77e-13 |
|
Bromo adjacent homology domain;
Pssm-ID: 214664 [Multi-domain] Cd Length: 121 Bit Score: 69.24 E-value: 1.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2800 MIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNN--MVVRVKWFYHPEETSPGKQFHegqhwdqksghslpaalrassqr 2877
Cdd:smart00439 1 TISVGDFVLVEPDDADEPYYIGRIEEIFETKKNSesKMVRVRWFYRPEETVLEKAAL----------------------- 57
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568938691 2878 kdFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQmLKTKKYQDSEGLYYLAGTYEPTTG 2938
Cdd:smart00439 58 --FDKNEVFLSDEYDTVPLSDIIGKCNVLYKSDYPG-LRPEGSIGEPDVFFCESAYDPEKG 115
|
|
| BAH |
pfam01426 |
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ... |
2799-2938 |
1.15e-10 |
|
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.
Pssm-ID: 460207 Cd Length: 120 Bit Score: 61.17 E-value: 1.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2799 EMIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMV-VRVKWFYHPEETSpgkqfhegqhwdqksgHSLPAAlrassqr 2877
Cdd:pfam01426 1 ETYSVGDFVLVEPDDADEPYYVARIEELFEDTKNGKKmVRVQWFYRPEETV----------------HRAGKA------- 57
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568938691 2878 kdFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKyqDSEGLYYLAGTYEPTTG 2938
Cdd:pfam01426 58 --FNKDELFLSDEEDDVPLSAIIGKCSVLHKSDLESLDPYKI--KEPDDFFCELLYDPKTK 114
|
|
| Tudor_3 |
pfam18115 |
DNA repair protein Crb2 Tudor domain; This is the tudor domain found in DNA repair protein ... |
2211-2263 |
1.51e-05 |
|
DNA repair protein Crb2 Tudor domain; This is the tudor domain found in DNA repair protein crb2. Structural and functional studies of Crb2 and its mammalian homolog 53BP1 indicate that the conserved tandem-Tudor domain of 53BP1 and Crb2 preferentially interacts with H4K20me2, though it also binds to H4K20me1. Furthermore, despite low amino acid sequence similarity, Crb2 is structurally related to 53BP1 in having two tudor domains and a conserved dimethyllysine-binding pocket, and that, like 53BP1, it directly binds H4-K20me2.
Pssm-ID: 436284 Cd Length: 50 Bit Score: 44.47 E-value: 1.51e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 568938691 2211 TRIAAYWSQQYRCLYPGTVVRgllDLEDDGDLITVEFDDGDTGRIPLSHIRLL 2263
Cdd:pfam18115 1 NRVFALWKGKDRAYYPATCLG---TSGSGSQRYLVRFDDGTPTEVDSGQVRRL 50
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2264-2478 |
1.34e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.48 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2264 PPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEVKEGAATGPQEATGGKARgrgRKPSTKA-KADRAVVLEEGAATNEVP 2342
Cdd:PRK12323 375 ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPAR---RSPAPEAlAAARQASARGPGGAPAPA 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2343 SAPLALEPISTPNSKKSTPEPVDKRARAPKARSISAQPSPVP---PTFSSCPA--PEPFGELPTPATAPLVTMPVTMPAT 2417
Cdd:PRK12323 452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADddpPPWEELPPefASPAPAQPDAAPAGWVAESIPDPAT 531
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568938691 2418 RPKPKKARAAEGSGAKGPRRPgeddellVKLDHEGVMSPKSKKAKEALLlrEDPGPGGWPE 2478
Cdd:PRK12323 532 ADPDDAFETLAPAPAAAPAPR-------AAAATEPVVAPRPPRASASGL--PDMFDGDWPA 583
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1048-1357 |
9.85e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 9.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1048 PFQALFTDIPPRYPFQALPPhyGRPYPFLLQPAAASDADglAPDVPLPADGPERLALSPEDKPICLSPSkiPEPPRDSPE 1127
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPP--PRPAPRPSEPAVTSRAR--RPDAPPQSARPRAPVDDRGDPRGPAPPS--PLPPDTHAP 2624
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1128 EEQLADREVKAEvEDIEEGPTELPPLESPLALPVPeTMVAVSPAGGCGGSPLEAQAlSTAGPGCRE-PSEVSDFAQVAEP 1206
Cdd:PHA03247 2625 DPPPPSPSPAAN-EPDPHPPPTVPPPERPRDDPAP-GRVSRPRRARRLGRAAQASS-PPQRPRRRAaRPTVGSLTSLADP 2701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1207 QIElPSKTEHRMTALELGTQLTPEPLVETKEEPVEVPLDVPMEEPTTEAGPED-----------------------SLPQ 1263
Cdd:PHA03247 2702 PPP-PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGparparppttagppapappaapaAGPP 2780
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1264 PSLTEPQ-PSLELSDCDLPVPEgqclnleAQEAVPAPASTCYLEETHSESLLPGLDDPLAGMNALAAAAELPQARPLPSL 1342
Cdd:PHA03247 2781 RRLTRPAvASLSESRESLPSPW-------DPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853
|
330
....*....|....*
gi 568938691 1343 GPGVPAGEKLDTAPS 1357
Cdd:PHA03247 2854 GSVAPGGDVRRRPPS 2868
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| BAH_BAHCC1 |
cd04714 |
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. ... |
2798-2942 |
5.03e-57 |
|
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.
Pssm-ID: 240065 Cd Length: 121 Bit Score: 193.77 E-value: 5.03e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2798 KEMIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKqfhegqhwdqksghslpaalrassqR 2877
Cdd:cd04714 1 KEIIRVGDCVLFKSPGRPSLPYVARIESLWEDPEGNMVVRVKWYYRPEETKGGR-------------------------K 55
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568938691 2878 KDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLK-TKKYQDSEGLYYLAGTYEPTTGMIFS 2942
Cdd:cd04714 56 PNHGEKELFASDHQDENSVQTIEHKCYVLTFAEYERLARvKKKPQDGVDFYYCAGTYNPDTGMLKC 121
|
|
| Tudor_TNRC18 |
cd20469 |
Tudor domain found in trinucleotide repeat-containing gene 18 protein (TNRC18) and similar ... |
2203-2269 |
9.72e-37 |
|
Tudor domain found in trinucleotide repeat-containing gene 18 protein (TNRC18) and similar proteins; TNRC18, also called long CAG trinucleotide repeat-containing gene 79 protein (CAGL79), is a protein that in humans is encoded by the TNRC18 gene. Its biological function remains unclear. TNRC18 contains one Tudor domain. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
Pssm-ID: 410540 Cd Length: 67 Bit Score: 133.70 E-value: 9.72e-37
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568938691 2203 STRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKI 2269
Cdd:cd20469 1 SVRFLPEGTRVCAYWSQQYRCLYPGTVVKGSPDPEEDDDLITVEFDDGDSGRIPLDHIRLLPPDYPI 67
|
|
| Tudor_BAHCC1-like |
cd20397 |
Tudor domain found in the BAH and coiled-coil domain-containing protein 1 (BAHCC1) family; The ... |
2203-2268 |
9.14e-30 |
|
Tudor domain found in the BAH and coiled-coil domain-containing protein 1 (BAHCC1) family; The family of BAHCC1 includes BAHCC1 and trinucleotide repeat-containing gene 18 protein (TNRC18). BAHCC1 may function as a transcriptional regulator. The biological function of TNRC18 remains unclear. Members of this family contain one Tudor domain. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
Pssm-ID: 410468 Cd Length: 67 Bit Score: 113.96 E-value: 9.14e-30
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568938691 2203 STRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDD-GDLITVEFDDGDTGRIPLSHIRLLPPDYK 2268
Cdd:cd20397 1 SVEYLPPGTRVCAYWSQQYRCLYPGTVISGEPDSEDSqEGKVPVEFDDGDSGKIPLSDIRLLPPDYP 67
|
|
| Tudor_BAHCC1 |
cd20470 |
Tudor domain found in BAH and coiled-coil domain-containing protein 1 (BAHCC1) and similar ... |
2201-2268 |
1.20e-24 |
|
Tudor domain found in BAH and coiled-coil domain-containing protein 1 (BAHCC1) and similar proteins; BAHCC1, also called Bromo adjacent homology domain-containing protein 2 (BAHD2), or BAH domain-containing protein 2, may function as a transcriptional regulator. BAHCC1 contains one Tudor domain. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
Pssm-ID: 410541 Cd Length: 70 Bit Score: 99.49 E-value: 1.20e-24
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2201 PASTRFLPQGTRIAAYWSQQYRCLYPGTVVR--GLLDLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYK 2268
Cdd:cd20470 1 PQSSRQLPPGTRVCAYWSQKSRCLYPGNVVRgsSGIDEEDDEDSVMVEFDDGDRGRISVSNIRLLPPDYK 70
|
|
| BAH |
cd04370 |
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). ... |
2798-2938 |
2.90e-21 |
|
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in mammalian DNA methyltransferases and the MTA1 subunits of histone deacetylase complexes. A BAH domain is also found in Yeast Sir3p and in the origin receptor complex protein 1 (Orc1p), where it was found to interact with the N-terminal lobe of the silence information regulator 1 protein (Sir1p), confirming the initial hypothesis that BAH plays a role in protein-protein interactions.
Pssm-ID: 239835 [Multi-domain] Cd Length: 123 Bit Score: 91.68 E-value: 2.90e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2798 KEMIRIGDCAVFLSAG--RPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKQFHEGqhwdqksghslpaalrass 2875
Cdd:cd04370 1 GITYEVGDSVYVEPDDsiKSDPPYIARIEELWEDTNGSKQVKVRWFYRPEETPKGLSPFAL------------------- 61
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568938691 2876 qrkdfmERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMlKTKKYQDSEGLYYLAGTYEPTTG 2938
Cdd:cd04370 62 ------RRELFLSDHLDEIPVESIIGKCKVLFVSEFEGL-KQRPNKIDTDDFFCRLAYDPTTK 117
|
|
| BAH |
smart00439 |
Bromo adjacent homology domain; |
2800-2938 |
1.77e-13 |
|
Bromo adjacent homology domain;
Pssm-ID: 214664 [Multi-domain] Cd Length: 121 Bit Score: 69.24 E-value: 1.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2800 MIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNN--MVVRVKWFYHPEETSPGKQFHegqhwdqksghslpaalrassqr 2877
Cdd:smart00439 1 TISVGDFVLVEPDDADEPYYIGRIEEIFETKKNSesKMVRVRWFYRPEETVLEKAAL----------------------- 57
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568938691 2878 kdFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQmLKTKKYQDSEGLYYLAGTYEPTTG 2938
Cdd:smart00439 58 --FDKNEVFLSDEYDTVPLSDIIGKCNVLYKSDYPG-LRPEGSIGEPDVFFCESAYDPEKG 115
|
|
| BAH |
pfam01426 |
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ... |
2799-2938 |
1.15e-10 |
|
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.
Pssm-ID: 460207 Cd Length: 120 Bit Score: 61.17 E-value: 1.15e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2799 EMIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMV-VRVKWFYHPEETSpgkqfhegqhwdqksgHSLPAAlrassqr 2877
Cdd:pfam01426 1 ETYSVGDFVLVEPDDADEPYYVARIEELFEDTKNGKKmVRVQWFYRPEETV----------------HRAGKA------- 57
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568938691 2878 kdFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKyqDSEGLYYLAGTYEPTTG 2938
Cdd:pfam01426 58 --FNKDELFLSDEEDDVPLSAIIGKCSVLHKSDLESLDPYKI--KEPDDFFCELLYDPKTK 114
|
|
| BAH_polybromo |
cd04717 |
BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human ... |
2800-2855 |
1.39e-07 |
|
BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional regulation. Saccharomyces cerevisiae RSC1 and RSC2 are part of the 15-subunit nucleosome remodeling RSC complex. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.
Pssm-ID: 240068 Cd Length: 121 Bit Score: 52.59 E-value: 1.39e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 568938691 2800 MIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEET--SPGKQFHE 2855
Cdd:cd04717 3 QYRVGDCVYVANPEDPSKPIIFRIERLWKDEDGEKFFFGCWFYRPEETfhEPTRKFYK 60
|
|
| BAH_plant_3 |
cd04713 |
BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH ... |
2783-2919 |
2.65e-06 |
|
BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.
Pssm-ID: 240064 Cd Length: 146 Bit Score: 49.39 E-value: 2.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2783 KGKARKLFYKAIVRGKEMIRIGDCAVFLSA-GRPnlPYIGRIQSMWESWGNNMVVRVKWFYHPEETspgkqfhegqhwDQ 2861
Cdd:cd04713 3 KGKKKKCHYTSFEKDGNKYRLEDCVLLVPEdDQK--PYIAIIKDIYKQEEGSLKLEVQWLYRPEEI------------EK 68
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 568938691 2862 KSGHSLPAAlrassqrkdfMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKK 2919
Cdd:cd04713 69 KKGGNWKAE----------DPRELFYSFHRDEVPAESVLHPCKVAFVPKGKQIPLRKG 116
|
|
| Tudor_3 |
pfam18115 |
DNA repair protein Crb2 Tudor domain; This is the tudor domain found in DNA repair protein ... |
2211-2263 |
1.51e-05 |
|
DNA repair protein Crb2 Tudor domain; This is the tudor domain found in DNA repair protein crb2. Structural and functional studies of Crb2 and its mammalian homolog 53BP1 indicate that the conserved tandem-Tudor domain of 53BP1 and Crb2 preferentially interacts with H4K20me2, though it also binds to H4K20me1. Furthermore, despite low amino acid sequence similarity, Crb2 is structurally related to 53BP1 in having two tudor domains and a conserved dimethyllysine-binding pocket, and that, like 53BP1, it directly binds H4-K20me2.
Pssm-ID: 436284 Cd Length: 50 Bit Score: 44.47 E-value: 1.51e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 568938691 2211 TRIAAYWSQQYRCLYPGTVVRgllDLEDDGDLITVEFDDGDTGRIPLSHIRLL 2263
Cdd:pfam18115 1 NRVFALWKGKDRAYYPATCLG---TSGSGSQRYLVRFDDGTPTEVDSGQVRRL 50
|
|
| Tudor_SF |
cd04508 |
Tudor domain superfamily; The Tudor domain is a conserved structural domain, originally ... |
2210-2262 |
1.06e-04 |
|
Tudor domain superfamily; The Tudor domain is a conserved structural domain, originally identified in the Tudor protein of Drosophila, that adopts a beta-barrel-like core structure containing four short beta-strands followed by an alpha-helical region. It binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions. Tudor domain-containing proteins may mediate protein-protein interactions required for various DNA-templated biological processes, such as RNA metabolism, as well as histone modification and the DNA damage response. Members of this superfamily contain one or more copies of the Tudor domain.
Pssm-ID: 410449 [Multi-domain] Cd Length: 47 Bit Score: 41.80 E-value: 1.06e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 568938691 2210 GTRIAAYWSQQyRCLYPGTVVRGLLDLEddgdlITVEFDDGDTGRIPLSHIRL 2262
Cdd:cd04508 1 GDRVEAKWSDD-GQWYPATVVAVNDDGK-----YTVLFDDGNEEEVSEDDIRP 47
|
|
| Tudor_SpCrb2-like_rpt1 |
cd20395 |
first Tudor domain found in Schizosaccharomyces pombe Cut5-repeat binding protein 2 (Crb2) and ... |
2210-2263 |
1.13e-04 |
|
first Tudor domain found in Schizosaccharomyces pombe Cut5-repeat binding protein 2 (Crb2) and similar proteins; Crb2, also called RAD9 protein homolog, or checkpoint mediator protein crb2, is a DNA repair protein essential for cell cycle arrest at the G1 and G2 stages following DNA damage by X-, and UV-irradiation, or inactivation of DNA ligase. Crb2 contains two Tudor domains. The model corresponds to the first one. The Tudor domain binds to proteins with dimethylated arginine or lysine residues, and may also bind methylated histone tails to facilitate protein-protein interactions.
Pssm-ID: 410466 Cd Length: 50 Bit Score: 41.96 E-value: 1.13e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 568938691 2210 GTRIAAYWSQqYRCLYPGTVVrglldLEDDGDLITVEFDDGDTGRIPLSHIRLL 2263
Cdd:cd20395 1 PTRVLAFWKG-DGNYYPATIV-----GPVSSSAYKVQFDDGTSSSVPPTQIRRL 48
|
|
| BAH_MTA |
cd04709 |
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The ... |
2800-2945 |
3.99e-04 |
|
BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.
Pssm-ID: 240060 Cd Length: 164 Bit Score: 43.53 E-value: 3.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2800 MIRIGDCAVFLSAgrPNLPY-IGRIQSMWESWGNNMVVRVKWFYHPEETSPgkqfHEGQHWDQKSGHSLPAALRASS-QR 2877
Cdd:cd04709 3 MYRVGDYVYFESS--PNNPYlIRRIEELNKTARGHVEAKVVCYYRRRDIPD----SLYQLADQHRRELEEKSDDLTPkQR 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568938691 2878 KDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQDSegLYYLAGtYEPTTGMIFSTDG 2945
Cdd:cd04709 77 HQLRHRELFLSRQVETLPATHIRGKCSVTLLNDTESARSYLAREDT--FFYSLV-YDPEQKTLLADQG 141
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
2264-2478 |
1.34e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.48 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2264 PPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEVKEGAATGPQEATGGKARgrgRKPSTKA-KADRAVVLEEGAATNEVP 2342
Cdd:PRK12323 375 ATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPAR---RSPAPEAlAAARQASARGPGGAPAPA 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2343 SAPLALEPISTPNSKKSTPEPVDKRARAPKARSISAQPSPVP---PTFSSCPA--PEPFGELPTPATAPLVTMPVTMPAT 2417
Cdd:PRK12323 452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADddpPPWEELPPefASPAPAQPDAAPAGWVAESIPDPAT 531
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568938691 2418 RPKPKKARAAEGSGAKGPRRPgeddellVKLDHEGVMSPKSKKAKEALLlrEDPGPGGWPE 2478
Cdd:PRK12323 532 ADPDDAFETLAPAPAAAPAPR-------AAAATEPVVAPRPPRASASGL--PDMFDGDWPA 583
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
2273-2523 |
2.65e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.62 E-value: 2.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2273 EPSPALLVPSAKRRSRKTSKDTGEVKEGAATGPQEATGGKARGRGRKPSTKAKADRAVVLEEGAATNEVPSAPLALEPIS 2352
Cdd:PHA03307 219 SPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSP 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2353 TPNSKKSTPEPvdkrARAPKARSISAQPSPVPP-TFSSCPAPEPFGELPTPATAPLVTMPVTMPATRPKPKKARAAEGSG 2431
Cdd:PHA03307 299 SPSSPGSGPAP----SSPRASSSSSSSRESSSSsTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRA 374
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2432 AKGPRRPGEDDEllvkldhegvmSPKSKKAKEALLLRED---PGPGGWPESTGLlslgsySPAVGSSEPKATWPkglDGD 2508
Cdd:PHA03307 375 PSSPAASAGRPT-----------RRRARAAVAGRARRRDatgRFPAGRPRPSPL------DAGAASGAFYARYP---LLT 434
|
250
....*....|....*
gi 568938691 2509 LTQEPGPGLPLEDPG 2523
Cdd:PHA03307 435 PSGEPWPGSPPPPPG 449
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
2273-2528 |
4.48e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.00 E-value: 4.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2273 EPSPALLVPS-------AKRRSRKTSKDTGEVKEGAATGPQEATGGKARGRGRKPST--KAKADRAVVLEEGAATNEVPS 2343
Cdd:PHA03247 2709 EPAPHALVSAtplppgpAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGppAPAPPAAPAAGPPRRLTRPAV 2788
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2344 APLALEPISTPNSKKSTPEPVDKRARAPKARSISAQPSPVPPTFSSCPAPEPFGELPTPATAPL---------------V 2408
Cdd:PHA03247 2789 ASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggsvapggdvrrrppS 2868
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2409 TMPVTMPATRPKPKKARAAEGSGAK----------GPRRPGEDDELLVKLDHEGVMSPKSKKAKEALLLREDPGPggwPE 2478
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSRstesfalppdQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPL---AP 2945
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 568938691 2479 STGLLSLGSYSPAVGSSEPKATWPKGLDGDLTQEPGPGLPLEDPGNSKNP 2528
Cdd:PHA03247 2946 TTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPP 2995
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
2305-2444 |
5.46e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.39 E-value: 5.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2305 PQEATGGKARGRGRKPSTKAKADRAVVLEEGAATNEVPSAPlalepisTPNSKKSTPEPVDKRARAPKARSISAQPSPVP 2384
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAA-------PAAAASAPAAPPAAAPPAPVAAPAAAAPAAAP 438
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 2385 PTFSSCPAPEPFgeLPTPATAPLVTMPVTMPATRPKPKKARAAEGSGAKGPRRPGEDDEL 2444
Cdd:PRK14951 439 AAAPAAVALAPA--PPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDV 496
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1048-1357 |
9.85e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.85 E-value: 9.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1048 PFQALFTDIPPRYPFQALPPhyGRPYPFLLQPAAASDADglAPDVPLPADGPERLALSPEDKPICLSPSkiPEPPRDSPE 1127
Cdd:PHA03247 2551 PPPPLPPAAPPAAPDRSVPP--PRPAPRPSEPAVTSRAR--RPDAPPQSARPRAPVDDRGDPRGPAPPS--PLPPDTHAP 2624
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1128 EEQLADREVKAEvEDIEEGPTELPPLESPLALPVPeTMVAVSPAGGCGGSPLEAQAlSTAGPGCRE-PSEVSDFAQVAEP 1206
Cdd:PHA03247 2625 DPPPPSPSPAAN-EPDPHPPPTVPPPERPRDDPAP-GRVSRPRRARRLGRAAQASS-PPQRPRRRAaRPTVGSLTSLADP 2701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1207 QIElPSKTEHRMTALELGTQLTPEPLVETKEEPVEVPLDVPMEEPTTEAGPED-----------------------SLPQ 1263
Cdd:PHA03247 2702 PPP-PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGparparppttagppapappaapaAGPP 2780
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568938691 1264 PSLTEPQ-PSLELSDCDLPVPEgqclnleAQEAVPAPASTCYLEETHSESLLPGLDDPLAGMNALAAAAELPQARPLPSL 1342
Cdd:PHA03247 2781 RRLTRPAvASLSESRESLPSPW-------DPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853
|
330
....*....|....*
gi 568938691 1343 GPGVPAGEKLDTAPS 1357
Cdd:PHA03247 2854 GSVAPGGDVRRRPPS 2868
|
|
| |
