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Conserved domains on  [gi|568914179|ref|XP_006498336|]
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cip1-interacting zinc finger protein isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10263 super family cl35903
DNA translocase FtsK; Provisional
 293-482 2.25e-07

DNA translocase FtsK; Provisional


The actual alignment was detected with superfamily member PRK10263:

Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 55.09  E-value: 2.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  293 TGQPQARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQALQIQTQPkllrqaqtqtSPEHLAPQQDQVEPQVPSQPP 372
Cdd:PRK10263  327 TTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAP----------APEGYPQQSQYAQPAVQYNEP 396

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  373 WQlQPRETDPPNQAQAQTQPQPLWQAQSQKQAQTQAHPQVPTQAQSQEQTSEKTQDQPQTWPQGSVPPPEQASGPACATE 452
Cdd:PRK10263  397 LQ-QPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQE 475

                         170       180       190
                  ....*....|....*....|....*....|
gi 568914179  453 PQlsSHAAEAGSDPDKALPEPVSAQSSEDR 482
Cdd:PRK10263  476 PL--YQQPQPVEQQPVVEPEPVVEETKPAR 503
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 651-675 1.89e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


:

Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.89e-05
                          10        20
                  ....*....|....*....|....*
gi 568914179  651 FCTICNRYFKTPRKFVEHVKSQGHK 675
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 767-800 1.63e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 36.85  E-value: 1.63e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 568914179   767 GYVCQICHKFYDSNSELRlSHCKSLAHFENLQKY 800
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
GIY-YIG_SF super family cl15257
GIY-YIG nuclease domain superfamily; The GIY-YIG nuclease domain superfamily includes a large ...
 620-687 2.91e-03

GIY-YIG nuclease domain superfamily; The GIY-YIG nuclease domain superfamily includes a large and diverse group of proteins involved in many cellular processes, such as class I homing GIY-YIG family endonucleases, prokaryotic nucleotide excision repair proteins UvrC and Cho, type II restriction enzymes, the endonuclease/reverse transcriptase of eukaryotic retrotransposable elements, and a family of eukaryotic enzymes that repair stalled replication forks. All of these members contain a conserved GIY-YIG nuclease domain that may serve as a scaffold for the coordination of a divalent metal ion required for catalysis of the phosphodiester bond cleavage. By combining with different specificity, targeting, or other domains, the GIY-YIG nucleases may perform different functions.


The actual alignment was detected with superfamily member cd10442:

Pssm-ID: 472790  Cd Length: 92  Bit Score: 37.73  E-value: 2.91e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 620 WCNTCQVYYVGDLIQ--HRRTQEHKVAKQSlrpfcticNRYFKTPrkFVEHVKSQGHKDKAQELKTLEKE 687
Cdd:cd10442    6 PCPKCGLVYIGETKRplRERMKEHRRAIRL--------SGTKKSA--VAKHFNEEGHSIDSDRVRILDKE 65
 
Name Accession Description Interval E-value
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 293-482 2.25e-07

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 55.09  E-value: 2.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  293 TGQPQARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQALQIQTQPkllrqaqtqtSPEHLAPQQDQVEPQVPSQPP 372
Cdd:PRK10263  327 TTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAP----------APEGYPQQSQYAQPAVQYNEP 396

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  373 WQlQPRETDPPNQAQAQTQPQPLWQAQSQKQAQTQAHPQVPTQAQSQEQTSEKTQDQPQTWPQGSVPPPEQASGPACATE 452
Cdd:PRK10263  397 LQ-QPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQE 475

                         170       180       190
                  ....*....|....*....|....*....|
gi 568914179  453 PQlsSHAAEAGSDPDKALPEPVSAQSSEDR 482
Cdd:PRK10263  476 PL--YQQPQPVEQQPVVEPEPVVEETKPAR 503
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 651-675 1.89e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.89e-05
                          10        20
                  ....*....|....*....|....*
gi 568914179  651 FCTICNRYFKTPRKFVEHVKSQGHK 675
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 300-458 1.59e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 45.41  E-value: 1.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  300 VQPQTQMTAPKQTQTPdrlPEPPEVQMLPRIQPQALQIQTQPKllrQAQTQTSPEHLAPQQDQvePQVPSQPPWQLQpre 379
Cdd:pfam09770 199 VEAAMRAQAKKPAQQP---APAPAQPPAAPPAQQAQQQQQFPP---QIQQQQQPQQQPQQPQQ--HPGQGHPVTILQ--- 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  380 tDPPNQAQAQTQPQPLWQAQSQKQAQTQAHPQvPTQA----QSQEQTSEKTQDQPQTWPQGSVPPPEQASGPACATEPQL 455
Cdd:pfam09770 268 -RPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQ-PTQIlqnpNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPI 345


                  ...
gi 568914179  456 SSH 458
Cdd:pfam09770 346 ITH 348
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 767-800 1.63e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 36.85  E-value: 1.63e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 568914179   767 GYVCQICHKFYDSNSELRlSHCKSLAHFENLQKY 800
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
GIY-YIG_PLEs cd10442
Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This ...
 620-687 2.91e-03

Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This model corresponds to the EN domain of PLEs that contains catalytic module of the GIY-YIG endonucleases of group I bacterial/organellar introns, as well as bacterial UvrC DNA repair proteins. It can cleave DNA with low nucleotide sequence specificity. However, the PLEs EN domain is distinct from other GIY-YIG endonucleases by the presence of a well-conserved CCHH motif (CX(2-7)CX(33-39)HX(3-5)H, X can be any residue). The role of the CCHH motif has not yet been identified. Penelope-like elements (PLEs) represent a novel class of eukaryotic retroelements, which do not belong to either long terminal repeat (LTR) retrotransposons or non-LTR retrotransposons (often called LINEs), but instead form a sister clade to telomerase reverse transcriptases (TERTs), highly specialized non-mobile reverse transcriptases (RTs) which are responsible for the addition of telomeric repeats to the ends of eukaryotic chromosomes. The single open reading frame (ORF) encoded by PLE consists of two principal domains, RT domain and endonuclease (EN) domain, jointed by a linker region of variable length. Both of these two domains are functionally active.


Pssm-ID: 198389  Cd Length: 92  Bit Score: 37.73  E-value: 2.91e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 620 WCNTCQVYYVGDLIQ--HRRTQEHKVAKQSlrpfcticNRYFKTPrkFVEHVKSQGHKDKAQELKTLEKE 687
Cdd:cd10442    6 PCPKCGLVYIGETKRplRERMKEHRRAIRL--------SGTKKSA--VAKHFNEEGHSIDSDRVRILDKE 65
 
Name Accession Description Interval E-value
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 293-482 2.25e-07

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 55.09  E-value: 2.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  293 TGQPQARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQALQIQTQPkllrqaqtqtSPEHLAPQQDQVEPQVPSQPP 372
Cdd:PRK10263  327 TTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAP----------APEGYPQQSQYAQPAVQYNEP 396

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  373 WQlQPRETDPPNQAQAQTQPQPLWQAQSQKQAQTQAHPQVPTQAQSQEQTSEKTQDQPQTWPQGSVPPPEQASGPACATE 452
Cdd:PRK10263  397 LQ-QPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQE 475

                         170       180       190
                  ....*....|....*....|....*....|
gi 568914179  453 PQlsSHAAEAGSDPDKALPEPVSAQSSEDR 482
Cdd:PRK10263  476 PL--YQQPQPVEQQPVVEPEPVVEETKPAR 503
PHA03247 PHA03247
large tegument protein UL36; Provisional
 130-488 1.46e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 52.25  E-value: 1.46e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  130 PSLAAPSLTPPQMVTPNLQQFFPQATRQSLLGPPPVGVPINPSQLNHSG-------RNTQKQARTPSSTTPNRK------ 196
Cdd:PHA03247 2609 RGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPApgrvsrpRRARRLGRAAQASSPPQRprrraa 2688

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  197 --------DSSSQTVPLEDREDPTEGSEEATELQMDTCEDQDSLVGPDSMLSEPQVPE-----------PEPFETLEPPA 257
Cdd:PHA03247 2689 rptvgsltSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAgpatpggparpARPPTTAGPPA 2768

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  258 KRCRRVRIKGIDHHnwlfAYLWIFASSEESTEKGPTgqPQARVQPQTQMTAPKQTQTPDRLP---EPPEVQMLPRIQPQA 334
Cdd:PHA03247 2769 PAPPAAPAAGPPRR----LTRPAVASLSESRESLPS--PWDPADPPAAVLAPAAALPPAASPagpLPPPTSAQPTAPPPP 2842

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  335 LQIQTQPKLLRQAQTQTSP--EHLAPQQDQVEPQVPSQPPWQLQPRETDPPNQAQAQTQPQPLwQAQSQKQAQTQAHPQV 412
Cdd:PHA03247 2843 PGPPPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQP-ERPPQPQAPPPPQPQP 2921

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568914179  413 PTQAQSQEQTSEKTQDQPQtwpqgsvPPPEQASGPACATEPQLSSHAAEAGSDPDKALPEPVSAQSSEDRSREASA 488
Cdd:PHA03247 2922 QPPPPPQPQPPPPPPPRPQ-------PPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPA 2990
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 282-493 4.65e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 50.37  E-value: 4.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 282 ASSEESTEKGPTGQPQARVQPQ--TQMTAPKQTQTPDRLPEPPEVQMLPRIQPQALQIQTQPKLLRQAQTQTSPEHLAPQ 359
Cdd:PRK07764 595 AGGEGPPAPASSGPPEEAARPAapAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAG 674

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 360 QDQVEPQVPSQPPWQLQPRETDPPNQAQAQTQpqplWQAQSQKQAQTQAHPQVPTQAQSQEQTSEKTQ----DQPQTWPQ 435
Cdd:PRK07764 675 GAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPA----ATPPAGQADDPAAQPPQAAQGASAPSPAADDPvplpPEPDDPPD 750

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 568914179 436 GSVPPPEQASGPACATEPQLSSHAAEA-GSDPDKALPEPVSAQSSEDRsREASAGGLDL 493
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPAAAPPPSpPSEEEEMAEDDAPSMDDEDR-RDAEEVAMEL 808
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 651-675 1.89e-05

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 42.16  E-value: 1.89e-05
                          10        20
                  ....*....|....*....|....*
gi 568914179  651 FCTICNRYFKTPRKFVEHVKSQGHK 675
Cdd:pfam12171   3 YCVLCDKYFKSENALQNHLKSKKHK 27
PRK10927 PRK10927
cell division protein FtsN;
286-444 3.48e-05

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 46.98  E-value: 3.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 286 ESTEKGPTGQPQARVQPQTQMTAPKQT---QTPDRLPEPPEVQMLPRIQPQALQIQTQPKLLRQAQTQTSPEHLAPQQDQ 362
Cdd:PRK10927 101 EPSAGGEVKTPEQLTPEQRQLLEQMQAdmrQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSRTTEQSWQ 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 363 VEPQVPSQPPWQLQPRetdPPNQAQAQTQPQPLWQAQSQKQAQTQAHPQVPT--QAQSQEQTSEKTQDQPQTWPQGSVPP 440
Cdd:PRK10927 181 QQTRTSQAAPVQAQPR---QSKPASTQQPYQDLLQTPAHTTAQSKPQQAAPVtrAADAPKPTAEKKDERRWMVQCGSFRG 257


                 ....
gi 568914179 441 PEQA 444
Cdd:PRK10927 258 AEQA 261
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 283-430 5.27e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 47.03  E-value: 5.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 283 SSEESTEKGPTGQPQARVQPQTQmTAPKQTQTPDRLPEPPEVQMLPR--IQPQALQIQTQPKLLRQAQTQTSPEHLAPQQ 360
Cdd:PRK14949 639 SSADRKPKTPPSRAPPASLSKPA-SSPDASQTSASFDLDPDFELATHqsVPEAALASGSAPAPPPVPDPYDRPPWEEAPE 717

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 361 DQVEPQVPSQPPwqlqpRETDPPNQAQAQTQPQPLWQAQSQKQAQTQAHPQVPTQAQSQEQTSEKTQDQP 430
Cdd:PRK14949 718 VASANDGPNNAA-----EGNLSESVEDASNSELQAVEQQATHQPQVQAEAQSPASTTALTQTSSEVQDTE 782
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 321-441 1.52e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 45.85  E-value: 1.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  321 PPEVQMLPRIQPQAlqiQTQPKLLRQAQTQTSPEHLAPQQDQVEPQVPSQPPWQLQPRETDPPNQAQAqtqpqplwqAQS 400
Cdd:PRK10263  740 PHEPLFTPIVEPVQ---QPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQY---------QQP 807

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 568914179  401 QKQAQTQAHPQVPTQAQSQEQTSEKTQDQPQTWPQGSVPPP 441
Cdd:PRK10263  808 QQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHP 848
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 300-458 1.59e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 45.41  E-value: 1.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  300 VQPQTQMTAPKQTQTPdrlPEPPEVQMLPRIQPQALQIQTQPKllrQAQTQTSPEHLAPQQDQvePQVPSQPPWQLQpre 379
Cdd:pfam09770 199 VEAAMRAQAKKPAQQP---APAPAQPPAAPPAQQAQQQQQFPP---QIQQQQQPQQQPQQPQQ--HPGQGHPVTILQ--- 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  380 tDPPNQAQAQTQPQPLWQAQSQKQAQTQAHPQvPTQA----QSQEQTSEKTQDQPQTWPQGSVPPPEQASGPACATEPQL 455
Cdd:pfam09770 268 -RPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQ-PTQIlqnpNRLSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAPI 345


                  ...
gi 568914179  456 SSH 458
Cdd:pfam09770 346 ITH 348
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 290-435 2.16e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 45.03  E-value: 2.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  290 KGPTGQPQARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQALQIQTQ----PKLLRQAQTQTSPEHLAPQQDQVEP 365
Cdd:pfam09770 208 KKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGqghpVTILQRPQSPQPDPAQPSIQPQAQQ 287

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568914179  366 QVPSQPPWQLQPRETDP-PNQAQAQTQPQPlwqaqsqkQAQTQAHPQVPTQAQSQEQTSEKTQDQPQTWPQ 435
Cdd:pfam09770 288 FHQQPPPVPVQPTQILQnPNRLSAARVGYP--------QNPQPGVQPAPAHQAHRQQGSFGRQAPIITHPQ 350
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 292-424 2.75e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 44.47  E-value: 2.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 292 PTGQPQARVQPQTQMTAPKQTQTPdrlPEPPEVQMLPRIQPQALQIQTQpklLRQAQTQTSPEHLAPQQDQVEPQVPSQP 371
Cdd:PRK07994 383 ATAAPTAAVAPPQAPAVPPPPASA---PQQAPAVPLPETTSQLLAARQQ---LQRAQGATKAKKSEPAAASRARPVNSAL 456

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 568914179 372 PW--QLQPRETDPPNQAQAQTQPQPLWQAQSQKQAQTQAHPQVPTQAQSQEQTSE 424
Cdd:PRK07994 457 ERlaSVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPE 511
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 295-380 2.99e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 44.69  E-value: 2.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  295 QPQARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQALQIQTQPkllrQAQTQTSPEHLAPQQDQVEPQVPSQPpwq 374
Cdd:PRK10263  767 QPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAP----QPQYQQPQQPVAPQPQYQQPQQPVAP--- 839


                  ....*.
gi 568914179  375 lQPRET 380
Cdd:PRK10263  840 -QPQDT 844
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 292-421 5.66e-04

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 43.49  E-value: 5.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  292 PTGQPQARVQPQTQmtAPKQTQTPDRLPEPPEVQMLPRIQPQALQIQTQPKLLRQAQTQTSPEHLAPQQDQVEPQVPSQP 371
Cdd:pfam09770 222 PAAPPAQQAQQQQQ--FPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQP 299

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568914179  372 PWQLQ-------PRETDPPNQAQAQTQPQPLWQAQSQ----KQAQTQAHPQVPTQAQSQEQ 421
Cdd:pfam09770 300 TQILQnpnrlsaARVGYPQNPQPGVQPAPAHQAHRQQgsfgRQAPIITHPQQLAQLSEEEK 360
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 292-383 1.42e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 42.38  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179  292 PTGQPQARVQPQTQMTAPKQTQTPDRLPEPPEVQMLPRIQPQALQIQTQPkllrQAQTQTSPEHLAPQQDQVEPQVP--S 369
Cdd:PRK10263  751 PVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAP----QPQYQQPQQPVAPQPQYQQPQQPvaP 826

                          90
                  ....*....|....
gi 568914179  370 QPPWQlQPRETDPP 383
Cdd:PRK10263  827 QPQYQ-QPQQPVAP 839
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 767-800 1.63e-03

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 36.85  E-value: 1.63e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 568914179   767 GYVCQICHKFYDSNSELRlSHCKSLAHFENLQKY 800
Cdd:smart00451   3 GFYCKLCNVTFTDEISVE-AHLKGKKHKKNVKKR 35
GIY-YIG_PLEs cd10442
Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This ...
 620-687 2.91e-03

Catalytic GIY-YIG endonuclease domain of penelope-like elements and similar proteins; This model corresponds to the EN domain of PLEs that contains catalytic module of the GIY-YIG endonucleases of group I bacterial/organellar introns, as well as bacterial UvrC DNA repair proteins. It can cleave DNA with low nucleotide sequence specificity. However, the PLEs EN domain is distinct from other GIY-YIG endonucleases by the presence of a well-conserved CCHH motif (CX(2-7)CX(33-39)HX(3-5)H, X can be any residue). The role of the CCHH motif has not yet been identified. Penelope-like elements (PLEs) represent a novel class of eukaryotic retroelements, which do not belong to either long terminal repeat (LTR) retrotransposons or non-LTR retrotransposons (often called LINEs), but instead form a sister clade to telomerase reverse transcriptases (TERTs), highly specialized non-mobile reverse transcriptases (RTs) which are responsible for the addition of telomeric repeats to the ends of eukaryotic chromosomes. The single open reading frame (ORF) encoded by PLE consists of two principal domains, RT domain and endonuclease (EN) domain, jointed by a linker region of variable length. Both of these two domains are functionally active.


Pssm-ID: 198389  Cd Length: 92  Bit Score: 37.73  E-value: 2.91e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 620 WCNTCQVYYVGDLIQ--HRRTQEHKVAKQSlrpfcticNRYFKTPrkFVEHVKSQGHKDKAQELKTLEKE 687
Cdd:cd10442    6 PCPKCGLVYIGETKRplRERMKEHRRAIRL--------SGTKKSA--VAKHFNEEGHSIDSDRVRILDKE 65
PRK10927 PRK10927
cell division protein FtsN;
297-452 7.21e-03

cell division protein FtsN;


Pssm-ID: 236797 [Multi-domain]  Cd Length: 319  Bit Score: 39.66  E-value: 7.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 297 QARVQPQTQMTAPKQTQTPDRLpEPPEVQMLPRIQPQALQIQTQpkLLRQAQTQTSPEHLAP--QQDQVEPQVPSQPPWQ 374
Cdd:PRK10927  93 QPGVRAPTEPSAGGEVKTPEQL-TPEQRQLLEQMQADMRQQPTQ--LVEVPWNEQTPEQRQQtlQRQRQAQQLAEQQRLA 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 375 LQPRETDPPNQAQAQTQPqplwqaQSQKQAQTQAHPQVPTQAQSQE--QTSEKTQDQPQtwPQGSVPPPEQASGPACATE 452
Cdd:PRK10927 170 QQSRTTEQSWQQQTRTSQ------AAPVQAQPRQSKPASTQQPYQDllQTPAHTTAQSK--PQQAAPVTRAADAPKPTAE 241
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 289-474 7.85e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.06  E-value: 7.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 289 EKGPTGQPQARVQPQtqmtAPKQTQTPDRlPEPPEVQMLPRI--------QPQALQIQTQPKLLRQAQTQTSPEHLAPQQ 360
Cdd:PTZ00449 566 EHKPSKIPTLSKKPE----FPKDPKHPKD-PEEPKKPKRPRSaqrptrpkSPKLPELLDIPKSPKRPESPKSPKRPPPPQ 640

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568914179 361 DQVEPQVPSQPPWQLQPRETDPPNQAQAQTQPQPLWQAQSQKQAQTQAHPQVPTQAQSQEQTSEKTQDQPQTWPQGSVP- 439
Cdd:PTZ00449 641 RPSSPERPEGPKIIKSPKPPKSPKPPFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILKETLPETPGTPFTTPRp 720

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 568914179 440 -PPEQASGPACATEPQlsshaaeagSDPDKALPEPV 474
Cdd:PTZ00449 721 lPPKLPRDEEFPFEPI---------GDPDAEQPDDI 747
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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