alpha-tubulin N-acetyltransferase 1 isoform X10 [Rattus norvegicus]
alpha-tubulin N-acetyltransferase( domain architecture ID 10526333)
alpha-tubulin N-acetyltransferase (TAT) acetylates Lys-40 of alpha-tubulin in the microtubule lumen
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
Acetyltransf_16 | pfam05301 | GNAT acetyltransferase, Mec-17; Mec-17 is the protein product of one of the 18 genes required ... |
10-190 | 6.08e-104 | ||||
GNAT acetyltransferase, Mec-17; Mec-17 is the protein product of one of the 18 genes required for the development and function of the touch receptor neuron for gentle touch. Mec-17 is specifically required for maintaining the differentiation of the touch receptor. The family shares all the residue-motifs characteriztic of Gcn5-related acetyl-transferases, though the exact unction is still unknown. : Pssm-ID: 461616 Cd Length: 176 Bit Score: 301.02 E-value: 6.08e-104
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Name | Accession | Description | Interval | E-value | ||||
Acetyltransf_16 | pfam05301 | GNAT acetyltransferase, Mec-17; Mec-17 is the protein product of one of the 18 genes required ... |
10-190 | 6.08e-104 | ||||
GNAT acetyltransferase, Mec-17; Mec-17 is the protein product of one of the 18 genes required for the development and function of the touch receptor neuron for gentle touch. Mec-17 is specifically required for maintaining the differentiation of the touch receptor. The family shares all the residue-motifs characteriztic of Gcn5-related acetyl-transferases, though the exact unction is still unknown. Pssm-ID: 461616 Cd Length: 176 Bit Score: 301.02 E-value: 6.08e-104
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NAT_SF | cd04301 | N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ... |
91-148 | 8.98e-03 | ||||
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included. Pssm-ID: 173926 [Multi-domain] Cd Length: 65 Bit Score: 34.17 E-value: 8.98e-03
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Name | Accession | Description | Interval | E-value | ||||
Acetyltransf_16 | pfam05301 | GNAT acetyltransferase, Mec-17; Mec-17 is the protein product of one of the 18 genes required ... |
10-190 | 6.08e-104 | ||||
GNAT acetyltransferase, Mec-17; Mec-17 is the protein product of one of the 18 genes required for the development and function of the touch receptor neuron for gentle touch. Mec-17 is specifically required for maintaining the differentiation of the touch receptor. The family shares all the residue-motifs characteriztic of Gcn5-related acetyl-transferases, though the exact unction is still unknown. Pssm-ID: 461616 Cd Length: 176 Bit Score: 301.02 E-value: 6.08e-104
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Acetyltransf_7 | pfam13508 | Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions. |
73-166 | 5.05e-03 | ||||
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions. Pssm-ID: 463905 [Multi-domain] Cd Length: 84 Bit Score: 35.51 E-value: 5.05e-03
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NAT_SF | cd04301 | N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ... |
91-148 | 8.98e-03 | ||||
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included. Pssm-ID: 173926 [Multi-domain] Cd Length: 65 Bit Score: 34.17 E-value: 8.98e-03
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Blast search parameters | ||||
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