|
Name |
Accession |
Description |
Interval |
E-value |
| COG5139 |
COG5139 |
Uncharacterized conserved protein [Function unknown]; |
474-725 |
1.35e-28 |
|
Uncharacterized conserved protein [Function unknown];
Pssm-ID: 227468 Cd Length: 397 Bit Score: 118.65 E-value: 1.35e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 474 DFEMMLQRKKSMCGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETF 553
Cdd:COG5139 126 ELGDTGDRQLKAPAASRARRKEDLLEQTVDEISLRLKKRMQDAAKKDNANNLEGRPATGKIKNLPEVSDVLMKKALQDTI 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 554 IDSGVMSAIKEWLSPLPDRSLPALKIREELLKILQELPsVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSR 633
Cdd:COG5139 206 LDNNILDSVRGWLEPLPDKSLPNIKIQKSLLDVLKTLP-IHTEHLVESGVGRIVYFYTISKKEEKEVRRSAKALVQEWTR 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 634 PIFGLTSNYKGmTREEREQRDLEQMPQRRRMSSTGGQTpRRDLEKVLTGEEKALRPGDPGFCARARV---PMPSNKDYVV 710
Cdd:COG5139 285 PIIKPSGNYRD-KRIMQLEFDSEKLRKKSVMDSAKNRK-KKSSGEDPTSRGSSVQTLYEQAAARRNRaaaPAQTTTDYKY 362
|
250
....*....|....*
gi 564393050 711 RPKWNVEMESSRIKM 725
Cdd:COG5139 363 APVSNLSAVPTNARA 377
|
|
| Med26 |
pfam08711 |
TFIIS helical bundle-like domain; Mediator is a large complex of up to 33 proteins that is ... |
582-635 |
2.29e-12 |
|
TFIIS helical bundle-like domain; Mediator is a large complex of up to 33 proteins that is conserved from plants to fungi to humans - the number and representation of individual subunits varying with species {1-2]. It is arranged into four different sections, a core, a head, a tail and a kinase-activity part, and the number of subunits within each of these is what varies with species. Overall, Mediator regulates the transcriptional activity of RNA polymerase II but it would appear that each of the four different sections has a slightly different function. Mediator exists in two major forms in human cells: a smaller form that interacts strongly with pol II and activates transcription, and a large form that does not interact strongly with pol II and does not directly activate transcription. Notably, the 'small' and 'large' Mediator complexes differ in their subunit composition: the Med26 subunit preferentially associates with the small, active complex, whereas cdk8, cyclin C, Med12 and Med13 associate with the large Mediator complex. This family includesthe C terminal region of a number of eukaryotic hypothetical proteins which are homologous to the Saccharomyces cerevisiae protein IWS1. IWS1 is known to be an Pol II transcription elongation factor and interacts with Spt6 and Spt5.
Pssm-ID: 462573 [Multi-domain] Cd Length: 52 Bit Score: 62.15 E-value: 2.29e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 564393050 582 ELLKILQELPsVSQETLKHSGIGRAVMYLYKHPkESRSNKDMAGKLINEWSRPI 635
Cdd:pfam08711 1 KLLKKLEKLP-VTLELLKSTGIGKVVNKLRKHK-ENPEIKKLAKELVKKWKRLV 52
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
66-417 |
8.28e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 65.70 E-value: 8.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 66 GTDSENDEPSNVHASDSESEElhrPKDSDSESEEHAESpASDSENEAVHQQGSDSEKeellnghASDSEKEEGRKHAASD 145
Cdd:NF033609 566 GSDSGSDSSNSDSGSDSGSDS---TSDSGSDSASDSDS-ASDSDSASDSDSASDSDS-------ASDSDSASDSDSASDS 634
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 146 SETEDTLQPQGSESDSEDPPRPQASDSESEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSESEelpkprvSDSE 225
Cdd:NF033609 635 DSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-------SDSD 707
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 226 SE-DPPRPQASDSESEelpkprvSDSESE-DPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKG 303
Cdd:NF033609 708 SDsDSDSDSDSDSDSD-------SDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 780
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 304 LHSSDSEEEEPKRQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVAS 383
Cdd:NF033609 781 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDS 860
|
330 340 350
....*....|....*....|....*....|....
gi 564393050 384 DSEEEVGKEESSVKKSEEKDlfGSDSESGNEEEN 417
Cdd:NF033609 861 NSDSESGSNNNVVPPNSPKN--GTNASNKNEAKD 892
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
2-353 |
1.37e-09 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 61.46 E-value: 1.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 2 DSEYYSGDQSDDGGATPVQDERDSGSDgEDDVNEQHSGSDTgsvDRHSENETSDREDGLTKIHNGTDSENDEPSNVHASD 81
Cdd:NF033609 577 DSGSDSGSDSTSDSGSDSASDSDSASD-SDSASDSDSASDS---DSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDS 652
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 82 SESEELHRPKDSDSESEEHAESPaSDSENEAVHQQGSDSEkeellnghaSDSEKEEGRKHAASDSETEDTLQPQGSESDS 161
Cdd:NF033609 653 DSDSDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSD---------SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 722
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 162 eDPPRPQASDSESEeppkpriSDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRPQASDSESEE 241
Cdd:NF033609 723 -DSDSDSDSDSDSD-------SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 242 LPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLHSSDSEEEEPKRQKI-- 319
Cdd:NF033609 795 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVvp 874
|
330 340 350
....*....|....*....|....*....|....*
gi 564393050 320 -DSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAA 353
Cdd:NF033609 875 pNSPKNGTNASNKNEAKDSKEPLPDTGSEDEANTS 909
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
149-463 |
5.78e-08 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 56.46 E-value: 5.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 149 EDTLQPQGSESDSEDPPRPQASDSESEEPPKPRiSDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESED 228
Cdd:NF033609 559 EDSDSDPGSDSGSDSSNSDSGSDSGSDSTSDSG-SDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSA 637
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 229 PPRPQASDSESEELPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLHSSD 308
Cdd:NF033609 638 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 717
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 309 SEEEEPKRQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASDSEEE 388
Cdd:NF033609 718 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 797
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564393050 389 VGKEESSVKKSEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAEDSDSDDNI 463
Cdd:NF033609 798 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNV 872
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
188-458 |
4.06e-07 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 53.85 E-value: 4.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 188 EELPKPRISDSESEDPPRPQVSDSESE-ELPKPRVSDSESEDPPRPQA-SDSESE-ELPKPRVSDSESEdpqkgpaSDSE 264
Cdd:TIGR00927 628 GDLSKGDVAEAEHTGERTGEEGERPTEaEGENGEESGGEAEQEGETETkGENESEgEIPAERKGEQEGE-------GEIE 700
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 265 AEDASrHKEKPESEDSDGENKREDSEVQNESDGHADRKGlhssdSEEEEPKRQKIDSDDDGEKEGDEKVAKRKA---AVL 341
Cdd:TIGR00927 701 AKEAD-HKGETEAEEVEHEGETEAEGTEDEGEIETGEEG-----EEVEDEGEGEAEGKHEVETEGDRKETEHEGeteAEG 774
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 342 SDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASDSEEEVGKEESSVKKSEEKDLFGSDS-ESGNEEENLIA 420
Cdd:TIGR00927 775 KEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQgEAKQDEKGVDG 854
|
250 260 270
....*....|....*....|....*....|....*...
gi 564393050 421 DIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAEDSD 458
Cdd:TIGR00927 855 GGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEE 892
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
156-474 |
4.34e-07 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 53.37 E-value: 4.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 156 GSESDSEDPPRPQASDSESEEPPKPRISDSESEELPKPRISDSES-EDPPRPQVSDSESEELPKPRVSDSESEDPPRPQA 234
Cdd:NF033609 534 GSGDGIDKPVVPEQPDEPGEIEPIPEDSDSDPGSDSGSDSSNSDSgSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSA 613
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 235 SDSES-----EELPKPRVSDSESE-DPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLHSSD 308
Cdd:NF033609 614 SDSDSasdsdSASDSDSASDSDSAsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 693
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 309 SEEEEPKRQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASDSEEE 388
Cdd:NF033609 694 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 773
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 389 VGKEESSVKKSEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAEDSDSDDNIKRGKH 468
Cdd:NF033609 774 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 853
|
....*.
gi 564393050 469 MDFLSD 474
Cdd:NF033609 854 SDSESD 859
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
82-331 |
6.58e-07 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 53.13 E-value: 6.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 82 SESEELHRPKDSDSESEEHAESPASDSENEAVHQQGSDSEKEELLNGHASDSEKEEGRKHAASDSETEDTlqpqGSESDS 161
Cdd:PTZ00108 1150 KEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSN----SSGSDQ 1225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 162 EDPPRPQASDSESEEPPKPRISDSESEElpkpriSDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPrpqasdseSEE 241
Cdd:PTZ00108 1226 EDDEEQKTKPKKSSVKRLKSKKNNSSKS------SEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPP--------SKR 1291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 242 LPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADR------KGLHSSDSEEEEPK 315
Cdd:PTZ00108 1292 PDGESNGGSKPSSPTKKKVKKRLEGSLAALKKKKKSEKKTARKKKSKTRVKQASASQSSRllrrprKKKSDSSSEDDDDS 1371
|
250
....*....|....*.
gi 564393050 316 RQKIDSDDDGEKEGDE 331
Cdd:PTZ00108 1372 EVDDSEDEDDEDDEDD 1387
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
11-260 |
1.76e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 45.14 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 11 SDDGGATPV-QDERDSGSDGEDDVNEQHSGSDTGSVDRHSENETSDREDGLTKIHNGTD---SENDEPSNVHASDSESEE 86
Cdd:pfam03154 27 SPDGRASPTnEDLRSSGRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSAKRQREkgaSDTEEPERATAKKSKTQE 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 87 LHRPkdsDSESEEHAESpasdSENEAVHQQGSdSEKEELLNGHASDSEKEEGRKHAASDSET---EDTLQPQGSESDSED 163
Cdd:pfam03154 107 ISRP---NSPSEGEGES----SDGRSVNDEGS-SDPKDIDQDNRSTSPSIPSPQDNESDSDSsaqQQILQTQPPVLQAQS 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 164 PPRPQASDSESEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSeseelPKPRVSDSESEDPPRPQASDSESEELP 243
Cdd:pfam03154 179 GAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAA-----PHTLIQQTPTLHPQRLPSPHPPLQPMT 253
|
250
....*....|....*..
gi 564393050 244 KPRVSDSESEDPQKGPA 260
Cdd:pfam03154 254 QPPPPSQVSPQPLPQPS 270
|
|
| MDN1 |
COG5271 |
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ... |
9-461 |
1.01e-03 |
|
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444083 [Multi-domain] Cd Length: 1028 Bit Score: 42.69 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 9 DQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVDRHSENETSDREDGLTKIHNGTDSENDEPSNVHASDSESEELH 88
Cdd:COG5271 513 ETSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAETEDATENADADETEESAD 592
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 89 RPKDSDSESEEHAESPASDSENEAVHQQGSdSEKEELLNGHASDSEKEEGRKHAASDSETEDTLQPQGSESDSEDPPRPQ 168
Cdd:COG5271 593 ESEEAEASEDEAAEEEEADDDEADADADGA-ADEEETEEEAAEDEAAEPETDASEAADEDADAETEAEASADESEEEAED 671
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 169 ASDSESEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRPQASDSESEELPKPrvS 248
Cdd:COG5271 672 ESETSSEDAEEDADAAAAEASDDEEETEEADEDAETASEEADAEEADTEADGTAEEAEEAAEEAESADEEAASLPDE--A 749
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 249 DSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLHSSDSEEEEPKRQKIDSDDDGEKE 328
Cdd:COG5271 750 DAEEEAEEAEEAEEDDADGLEEALEEEKADAEEAATDEEAEAAAEEKEKVADEDQDTDEDALLDEAEADEEEDLDGEDEE 829
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 329 GDEKVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASDSEEEVGKEESSVKKSEEKDLFGSD 408
Cdd:COG5271 830 TADEALEDIEAGIAEDDEEDDDAAAAKDVDADLDLDADLAADEHEAEEAQEAETDADADADAGEADSSGESSAAAEDDDA 909
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 564393050 409 SESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAEDSDSDD 461
Cdd:COG5271 910 AEDADSDDGANDEDDDDDAEEERKDAEEDELGAAEDDLDALALDEAGDEESDD 962
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG5139 |
COG5139 |
Uncharacterized conserved protein [Function unknown]; |
474-725 |
1.35e-28 |
|
Uncharacterized conserved protein [Function unknown];
Pssm-ID: 227468 Cd Length: 397 Bit Score: 118.65 E-value: 1.35e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 474 DFEMMLQRKKSMCGKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPALKKLTLLPTVVMHLKKQDLKETF 553
Cdd:COG5139 126 ELGDTGDRQLKAPAASRARRKEDLLEQTVDEISLRLKKRMQDAAKKDNANNLEGRPATGKIKNLPEVSDVLMKKALQDTI 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 554 IDSGVMSAIKEWLSPLPDRSLPALKIREELLKILQELPsVSQETLKHSGIGRAVMYLYKHPKESRSNKDMAGKLINEWSR 633
Cdd:COG5139 206 LDNNILDSVRGWLEPLPDKSLPNIKIQKSLLDVLKTLP-IHTEHLVESGVGRIVYFYTISKKEEKEVRRSAKALVQEWTR 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 634 PIFGLTSNYKGmTREEREQRDLEQMPQRRRMSSTGGQTpRRDLEKVLTGEEKALRPGDPGFCARARV---PMPSNKDYVV 710
Cdd:COG5139 285 PIIKPSGNYRD-KRIMQLEFDSEKLRKKSVMDSAKNRK-KKSSGEDPTSRGSSVQTLYEQAAARRNRaaaPAQTTTDYKY 362
|
250
....*....|....*
gi 564393050 711 RPKWNVEMESSRIKM 725
Cdd:COG5139 363 APVSNLSAVPTNARA 377
|
|
| Med26 |
pfam08711 |
TFIIS helical bundle-like domain; Mediator is a large complex of up to 33 proteins that is ... |
582-635 |
2.29e-12 |
|
TFIIS helical bundle-like domain; Mediator is a large complex of up to 33 proteins that is conserved from plants to fungi to humans - the number and representation of individual subunits varying with species {1-2]. It is arranged into four different sections, a core, a head, a tail and a kinase-activity part, and the number of subunits within each of these is what varies with species. Overall, Mediator regulates the transcriptional activity of RNA polymerase II but it would appear that each of the four different sections has a slightly different function. Mediator exists in two major forms in human cells: a smaller form that interacts strongly with pol II and activates transcription, and a large form that does not interact strongly with pol II and does not directly activate transcription. Notably, the 'small' and 'large' Mediator complexes differ in their subunit composition: the Med26 subunit preferentially associates with the small, active complex, whereas cdk8, cyclin C, Med12 and Med13 associate with the large Mediator complex. This family includesthe C terminal region of a number of eukaryotic hypothetical proteins which are homologous to the Saccharomyces cerevisiae protein IWS1. IWS1 is known to be an Pol II transcription elongation factor and interacts with Spt6 and Spt5.
Pssm-ID: 462573 [Multi-domain] Cd Length: 52 Bit Score: 62.15 E-value: 2.29e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 564393050 582 ELLKILQELPsVSQETLKHSGIGRAVMYLYKHPkESRSNKDMAGKLINEWSRPI 635
Cdd:pfam08711 1 KLLKKLEKLP-VTLELLKSTGIGKVVNKLRKHK-ENPEIKKLAKELVKKWKRLV 52
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
66-417 |
8.28e-11 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 65.70 E-value: 8.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 66 GTDSENDEPSNVHASDSESEElhrPKDSDSESEEHAESpASDSENEAVHQQGSDSEKeellnghASDSEKEEGRKHAASD 145
Cdd:NF033609 566 GSDSGSDSSNSDSGSDSGSDS---TSDSGSDSASDSDS-ASDSDSASDSDSASDSDS-------ASDSDSASDSDSASDS 634
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 146 SETEDTLQPQGSESDSEDPPRPQASDSESEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSESEelpkprvSDSE 225
Cdd:NF033609 635 DSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD-------SDSD 707
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 226 SE-DPPRPQASDSESEelpkprvSDSESE-DPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKG 303
Cdd:NF033609 708 SDsDSDSDSDSDSDSD-------SDSDSDsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 780
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 304 LHSSDSEEEEPKRQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVAS 383
Cdd:NF033609 781 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDS 860
|
330 340 350
....*....|....*....|....*....|....
gi 564393050 384 DSEEEVGKEESSVKKSEEKDlfGSDSESGNEEEN 417
Cdd:NF033609 861 NSDSESGSNNNVVPPNSPKN--GTNASNKNEAKD 892
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
2-353 |
1.37e-09 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 61.46 E-value: 1.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 2 DSEYYSGDQSDDGGATPVQDERDSGSDgEDDVNEQHSGSDTgsvDRHSENETSDREDGLTKIHNGTDSENDEPSNVHASD 81
Cdd:NF033609 577 DSGSDSGSDSTSDSGSDSASDSDSASD-SDSASDSDSASDS---DSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDS 652
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 82 SESEELHRPKDSDSESEEHAESPaSDSENEAVHQQGSDSEkeellnghaSDSEKEEGRKHAASDSETEDTLQPQGSESDS 161
Cdd:NF033609 653 DSDSDSDSDSDSDSDSDSDSDSD-SDSDSDSDSDSDSDSD---------SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 722
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 162 eDPPRPQASDSESEeppkpriSDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRPQASDSESEE 241
Cdd:NF033609 723 -DSDSDSDSDSDSD-------SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 242 LPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLHSSDSEEEEPKRQKI-- 319
Cdd:NF033609 795 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNVvp 874
|
330 340 350
....*....|....*....|....*....|....*
gi 564393050 320 -DSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAA 353
Cdd:NF033609 875 pNSPKNGTNASNKNEAKDSKEPLPDTGSEDEANTS 909
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
149-463 |
5.78e-08 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 56.46 E-value: 5.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 149 EDTLQPQGSESDSEDPPRPQASDSESEEPPKPRiSDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESED 228
Cdd:NF033609 559 EDSDSDPGSDSGSDSSNSDSGSDSGSDSTSDSG-SDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSASDSDSA 637
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 229 PPRPQASDSESEELPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLHSSD 308
Cdd:NF033609 638 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 717
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 309 SEEEEPKRQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASDSEEE 388
Cdd:NF033609 718 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 797
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564393050 389 VGKEESSVKKSEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAEDSDSDDNI 463
Cdd:NF033609 798 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGSNNNV 872
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
188-458 |
4.06e-07 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 53.85 E-value: 4.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 188 EELPKPRISDSESEDPPRPQVSDSESE-ELPKPRVSDSESEDPPRPQA-SDSESE-ELPKPRVSDSESEdpqkgpaSDSE 264
Cdd:TIGR00927 628 GDLSKGDVAEAEHTGERTGEEGERPTEaEGENGEESGGEAEQEGETETkGENESEgEIPAERKGEQEGE-------GEIE 700
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 265 AEDASrHKEKPESEDSDGENKREDSEVQNESDGHADRKGlhssdSEEEEPKRQKIDSDDDGEKEGDEKVAKRKA---AVL 341
Cdd:TIGR00927 701 AKEAD-HKGETEAEEVEHEGETEAEGTEDEGEIETGEEG-----EEVEDEGEGEAEGKHEVETEGDRKETEHEGeteAEG 774
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 342 SDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASDSEEEVGKEESSVKKSEEKDLFGSDS-ESGNEEENLIA 420
Cdd:TIGR00927 775 KEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQgEAKQDEKGVDG 854
|
250 260 270
....*....|....*....|....*....|....*...
gi 564393050 421 DIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAEDSD 458
Cdd:TIGR00927 855 GGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENEE 892
|
|
| MSCRAMM_ClfA |
NF033609 |
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ... |
156-474 |
4.34e-07 |
|
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.
Pssm-ID: 468110 [Multi-domain] Cd Length: 934 Bit Score: 53.37 E-value: 4.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 156 GSESDSEDPPRPQASDSESEEPPKPRISDSESEELPKPRISDSES-EDPPRPQVSDSESEELPKPRVSDSESEDPPRPQA 234
Cdd:NF033609 534 GSGDGIDKPVVPEQPDEPGEIEPIPEDSDSDPGSDSGSDSSNSDSgSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSA 613
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 235 SDSES-----EELPKPRVSDSESE-DPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLHSSD 308
Cdd:NF033609 614 SDSDSasdsdSASDSDSASDSDSAsDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 693
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 309 SEEEEPKRQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASDSEEE 388
Cdd:NF033609 694 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 773
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 389 VGKEESSVKKSEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAEDSDSDDNIKRGKH 468
Cdd:NF033609 774 SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD 853
|
....*.
gi 564393050 469 MDFLSD 474
Cdd:NF033609 854 SDSESD 859
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
82-331 |
6.58e-07 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 53.13 E-value: 6.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 82 SESEELHRPKDSDSESEEHAESPASDSENEAVHQQGSDSEKEELLNGHASDSEKEEGRKHAASDSETEDTlqpqGSESDS 161
Cdd:PTZ00108 1150 KEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSN----SSGSDQ 1225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 162 EDPPRPQASDSESEEPPKPRISDSESEElpkpriSDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPrpqasdseSEE 241
Cdd:PTZ00108 1226 EDDEEQKTKPKKSSVKRLKSKKNNSSKS------SEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPP--------SKR 1291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 242 LPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADR------KGLHSSDSEEEEPK 315
Cdd:PTZ00108 1292 PDGESNGGSKPSSPTKKKVKKRLEGSLAALKKKKKSEKKTARKKKSKTRVKQASASQSSRllrrprKKKSDSSSEDDDDS 1371
|
250
....*....|....*.
gi 564393050 316 RQKIDSDDDGEKEGDE 331
Cdd:PTZ00108 1372 EVDDSEDEDDEDDEDD 1387
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
83-467 |
2.13e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.30 E-value: 2.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 83 ESEELHRPKDSDSESEEHAESPASDSENEAVHQQGSDSEKEELLNGHASDSEKEEGRKHAASDSETEDTLQPQGSESDSE 162
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKA 1485
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 163 DPPRPQASDSE--SEEPPKPRISDSESEELPKPRisDSESEDPPRPQVSDSESEELPKprVSDSESEDPPRPQASDSESE 240
Cdd:PTZ00121 1486 DEAKKKAEEAKkkADEAKKAAEAKKKADEAKKAE--EAKKADEAKKAEEAKKADEAKK--AEEKKKADELKKAEELKKAE 1561
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 241 ELPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHadrkgLHSSDSEEEEPKRQKID 320
Cdd:PTZ00121 1562 EKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK-----IKAEELKKAEEEKKKVE 1636
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 321 SDDDGEKEgdekvAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASDSEEEVGKEESSVKKSE 400
Cdd:PTZ00121 1637 QLKKKEAE-----EKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564393050 401 EKDLFGSDSESGNEEENLI-ADIFGESGDEEEEEFTGFNQEdlEEEKNETQLKEAEDSDSDDNIKRGK 467
Cdd:PTZ00121 1712 AEEKKKAEELKKAEEENKIkAEEAKKEAEEDKKKAEEAKKD--EEEKKKIAHLKKEEEKKAEEIRKEK 1777
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
72-456 |
2.66e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 51.30 E-value: 2.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 72 DEPSNVHASDSESEELHRPKDSDSESEEhAESPASDSENEAVHQQGSDSEKEELLNGHASDSEKEEGRKHAASDSETEDT 151
Cdd:PTZ00121 1299 EEKKKADEAKKKAEEAKKADEAKKKAEE-AKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAK 1377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 152 LQPQGSESDSEDPPRPQASDSESEEPPKprisdsESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPR 231
Cdd:PTZ00121 1378 KKADAAKKKAEEKKKADEAKKKAEEDKK------KADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKK 1451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 232 PQASDSESEELPKPRVSDSESEDPQKGPASDSEAEDASRHKEKP-----ESEDSDGENKREDSEVQNESDGHAD--RKGL 304
Cdd:PTZ00121 1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAkkkadEAKKAAEAKKKADEAKKAEEAKKADeaKKAE 1531
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 305 HSSDSEEEEPKRQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASD 384
Cdd:PTZ00121 1532 EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEE 1611
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564393050 385 S--EEEVGKEESSVKKSEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAED 456
Cdd:PTZ00121 1612 AkkAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE 1685
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
47-289 |
2.75e-06 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 51.20 E-value: 2.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 47 RHSENETSDREDGLTKIHNGTDSENDEPSNVHASDSESEELHRPKDSDSESEEHAESPASDSENEAVHQQGSDSEKEEll 126
Cdd:PTZ00108 1156 QRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKT-- 1233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 127 nGHASDSEKEEGRKHAASDSETEDTLQPQGSESDSEDPPR--PQASDSESEEPPKPrisdseSEELPKPRISDSESEDPP 204
Cdd:PTZ00108 1234 -KPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKnaPKRVSAVQYSPPPP------SKRPDGESNGGSKPSSPT 1306
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 205 RPQVSDSESEELPKPRVSDSESEDPPRPQASDSESEELPKPRVSDSESEDPQKGPASDSEAEDASrhkEKPESEDSDGEN 284
Cdd:PTZ00108 1307 KKKVKKRLEGSLAALKKKKKSEKKTARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSEDDDDS---EVDDSEDEDDED 1383
|
....*
gi 564393050 285 KREDS 289
Cdd:PTZ00108 1384 DEDDD 1388
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
50-297 |
4.06e-06 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 50.46 E-value: 4.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 50 ENETSDREDGLTKihnGTDSENDEPSNvhASDSESEELHRPKDSDSESEEHAESPASDSENEAVHQQGSdsekeellngh 129
Cdd:PTZ00449 500 EEEDSDKHDEPPE---GPEASGLPPKA--PGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGP----------- 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 130 asdsekeeGRKHAASDSETEdTLQPQGSEsDSEDPPRPqasdsesEEPPKPRISDSESEELPKPRISDSESEDPPRpQVS 209
Cdd:PTZ00449 564 --------AKEHKPSKIPTL-SKKPEFPK-DPKHPKDP-------EEPKKPKRPRSAQRPTRPKSPKLPELLDIPK-SPK 625
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 210 DSESEELPKPRVSDSESEDPPRPQAsdSESEELPKPRVSDSESEDPQ-KGPASDSEAEDASRHKEKPESEDSDGENKRED 288
Cdd:PTZ00449 626 RPESPKSPKRPPPPQRPSSPERPEG--PKIIKSPKPPKSPKPPFDPKfKEKFYDDYLDAAAKSKETKTTVVLDESFESIL 703
|
....*....
gi 564393050 289 SEVQNESDG 297
Cdd:PTZ00449 704 KETLPETPG 712
|
|
| PRK08581 |
PRK08581 |
amidase domain-containing protein; |
100-356 |
7.89e-06 |
|
amidase domain-containing protein;
Pssm-ID: 236304 [Multi-domain] Cd Length: 619 Bit Score: 49.40 E-value: 7.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 100 HAESPASDSENEAVHQQGSDSEKEELLNGHASDSEKEEgrkHAASDSETEDTLQPQGSESDSEDPprpqaSDSESEEPPK 179
Cdd:PRK08581 26 YADDPQKDSTAKTTSHDSKKSNDDETSKDTSSKDTDKA---DNNNTSNQDNNDKKFSTIDSSTSD-----SNNIIDFIYK 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 180 PRISDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRPQASDSESEELPKPRVSDSESEDPQKGP 259
Cdd:PRK08581 98 NLPQTNINQLLTKNKYDDNYSLTTLIQNLFNLNSDISDYEQPRNSEKSTNDSNKNSDSSIKNDTDTQSSKQDKADNQKAP 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 260 ASDSEAEDASRHKEKPE--------SEDSDGENKREDSEVQNESDGHADRKGLHSSDSEEEEPKRQKIDSDDDGEKEGDE 331
Cdd:PRK08581 178 SSNNTKPSTSNKQPNSPkptqpnqsNSQPASDDTANQKSSSKDNQSMSDSALDSILDQYSEDAKKTQKDYASQSKKDKTE 257
|
250 260
....*....|....*....|....*
gi 564393050 332 KVAKRKAAVLSDSEDEDKASAAKKS 356
Cdd:PRK08581 258 TSNTKNPQLPTQDELKHKSKPAQSF 282
|
|
| PRK12678 |
PRK12678 |
transcription termination factor Rho; Provisional |
135-332 |
1.67e-05 |
|
transcription termination factor Rho; Provisional
Pssm-ID: 237171 [Multi-domain] Cd Length: 672 Bit Score: 48.36 E-value: 1.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 135 KEEGRKHAASDSETEDTLQPQGSESDSEDPPRPQASDSESEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSESE 214
Cdd:PRK12678 56 KEARGGGAAAAAATPAAPAAAARRAARAAAAARQAEQPAAEAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGE 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 215 ELPKPRVSDSESEDPPRPQASDSESEELPKPRVSDSESEDPQKGPASDSE--AEDASRHKEKPESEDSDGENKREDSEvQ 292
Cdd:PRK12678 136 AARRGAARKAGEGGEQPATEARADAAERTEEEERDERRRRGDREDRQAEAerGERGRREERGRDGDDRDRRDRREQGD-R 214
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 564393050 293 NESDGHAD--------RKGLHSSDSEEEEPKRQKIDSDDDGEKEGDEK 332
Cdd:PRK12678 215 REERGRRDggdrrgrrRRRDRRDARGDDNREDRGDRDGDDGEGRGGRR 262
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
128-336 |
1.88e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.06 E-value: 1.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 128 GHASDSEKEEGRKHAASDSETEDTLQPQGSESDSEDP-PRPQASDSESEEPPKPRISDSESEELPKPRISDSESEDPPRP 206
Cdd:PRK07764 589 GPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAaPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDG 668
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 207 QVSD------SESEELPKPRVSDSESEDPPRPQASDSESEElPKPRVSDSESEDPQK----GPASDSEAEDASRHKEKPE 276
Cdd:PRK07764 669 WPAKaggaapAAPPPAPAPAAPAAPAGAAPAQPAPAPAATP-PAGQADDPAAQPPQAaqgaSAPSPAADDPVPLPPEPDD 747
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 277 SEDSDGENKREDSEVQNESDGHADRKGLHSSDSEEEEPKRQKIDSDDDGEKEGDEKVAKR 336
Cdd:PRK07764 748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVAME 807
|
|
| PHA03321 |
PHA03321 |
tegument protein VP11/12; Provisional |
161-331 |
2.11e-05 |
|
tegument protein VP11/12; Provisional
Pssm-ID: 223041 [Multi-domain] Cd Length: 694 Bit Score: 48.03 E-value: 2.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 161 SEDPPRPQASDSESEEPPKPRISDSESEElpKPRISDSESEDPPRPQVSDSESE--ELPKPRVSDSESEDPPRPQA---S 235
Cdd:PHA03321 427 SRQPPGAPAPRRDNDPPPPPRARPGSTPA--CARRARAQRARDAGPEYVDPLGAlrRLPAGAAPPPEPAAAPSPATyytR 504
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 236 DSESEELPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRK---GLHSSDSEE- 311
Cdd:PHA03321 505 MGGGPPRLPPRNRATETLRPDWGPPAAAPPEQMEDPYLEPDDDRFDRRDGAAAAATSHPREAPAPDDdpiYEGVSDSEEp 584
|
170 180
....*....|....*....|....
gi 564393050 312 --EEPKRQKI--DSDDDGEKEGDE 331
Cdd:PHA03321 585 vyEEIPTPRVyqNPLPRPMEGAGE 608
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
92-332 |
5.17e-05 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 46.91 E-value: 5.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 92 DSDSESEEHAESPASDSENEAVHQQGSDSEKEELLNGHA-SDSEKE---EGRKHAASDSETEDTLQPQGSESDSEDPPRP 167
Cdd:TIGR00927 639 EHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGeNESEGEipaERKGEQEGEGEIEAKEADHKGETEAEEVEHE 718
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 168 QASDSESEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRPQASD------SESEE 241
Cdd:TIGR00927 719 GETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQAGEdgemkgDEGAE 798
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 242 LPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLHSSDSEEEEpkrqkiDS 321
Cdd:TIGR00927 799 GKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSDGGDSEEEEEEE------EE 872
|
250
....*....|.
gi 564393050 322 DDDGEKEGDEK 332
Cdd:TIGR00927 873 EEEEEEEEEEE 883
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
186-411 |
1.37e-04 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 45.42 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 186 ESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRPQASDSESEELPKPRVSDSESEDPQKGPASDSEA 265
Cdd:PTZ00108 1154 KEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKT 1233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 266 EDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGL------HSSDSEEEEPKR---QKIDSDDDGEKEGDEKVAKR 336
Cdd:PTZ00108 1234 KPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKnapkrvSAVQYSPPPPSKrpdGESNGGSKPSSPTKKKVKKR 1313
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564393050 337 K---AAVLSDSEDEDKASAAKKSrviSDADDSDSDVVSDKSGKREKTVASDSEEEVGKEESSVKKSEEKDLFGSDSES 411
Cdd:PTZ00108 1314 LegsLAALKKKKKSEKKTARKKK---SKTRVKQASASQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDDEDDEDDD 1388
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
11-260 |
1.76e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 45.14 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 11 SDDGGATPV-QDERDSGSDGEDDVNEQHSGSDTGSVDRHSENETSDREDGLTKIHNGTD---SENDEPSNVHASDSESEE 86
Cdd:pfam03154 27 SPDGRASPTnEDLRSSGRNSPSAASTSSNDSKAESMKKSSKKIKEEAPSPLKSAKRQREkgaSDTEEPERATAKKSKTQE 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 87 LHRPkdsDSESEEHAESpasdSENEAVHQQGSdSEKEELLNGHASDSEKEEGRKHAASDSET---EDTLQPQGSESDSED 163
Cdd:pfam03154 107 ISRP---NSPSEGEGES----SDGRSVNDEGS-SDPKDIDQDNRSTSPSIPSPQDNESDSDSsaqQQILQTQPPVLQAQS 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 164 PPRPQASDSESEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSeseelPKPRVSDSESEDPPRPQASDSESEELP 243
Cdd:pfam03154 179 GAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAA-----PHTLIQQTPTLHPQRLPSPHPPLQPMT 253
|
250
....*....|....*..
gi 564393050 244 KPRVSDSESEDPQKGPA 260
Cdd:pfam03154 254 QPPPPSQVSPQPLPQPS 270
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
74-314 |
2.54e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 44.31 E-value: 2.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 74 PSNVHASDS----ESEELHRPKDSDSESEEHAESPASDSENEAVhqQGSDSEKEEllnghasdsekeegrkhAASDSETE 149
Cdd:PRK08691 360 PLAAASCDAnaviENTELQSPSAQTAEKETAAKKPQPRPEAETA--QTPVQTASA-----------------AAMPSEGK 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 150 dTLQPQGSESDSEDPPRPQASD-SESEEPPKPRISDSESeelpkpriSDSESEDPPRPQVSdseseelpKPRVSDSESED 228
Cdd:PRK08691 421 -TAGPVSNQENNDVPPWEDAPDeAQTAAGTAQTSAKSIQ--------TASEAETPPENQVS--------KNKAADNETDA 483
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 229 PPRPQASDSESEELPKPRVSDSES---EDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLH 305
Cdd:PRK08691 484 PLSEVPSENPIQATPNDEAVETETfahEAPAEPFYGYGFPDNDCPPEDGAEIPPPDWEHAAPADTAGGGADEEAEAGGIG 563
|
....*....
gi 564393050 306 SSDSEEEEP 314
Cdd:PRK08691 564 GNNTPSAPP 572
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
92-332 |
2.91e-04 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 44.22 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 92 DSDSESEEHAESPASDSENEAVHQQGSDSEKEELLNGHASDSEKEEGRKHAASDSETEDTLQ-PQGSESDSEDPPRPQAS 170
Cdd:TIGR00927 629 DLSKGDVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEGETETKGENESEGEIPAERKgEQEGEGEIEAKEADHKG 708
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 171 DSESEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRPQASDSESEELPKPRVSDS 250
Cdd:TIGR00927 709 ETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQAGED 788
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 251 -----ESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQ-----NESDGHADRKGLHSS------DSEEEEP 314
Cdd:TIGR00927 789 gemkgDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQelnaeNQGEAKQDEKGVDGGggsdggDSEEEEE 868
|
250
....*....|....*...
gi 564393050 315 KRQKIDSDDDGEKEGDEK 332
Cdd:TIGR00927 869 EEEEEEEEEEEEEEEEEE 886
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
153-332 |
3.55e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 44.16 E-value: 3.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 153 QPQGSESDSEDPPRPQASDSESEEPPKPRISDSESEELPKPRISDSE-------------SEDPPRPQVSDSESEELPKP 219
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPlapttdpagagepSGAVPQPWLGALVPGRVAVP 2975
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 220 RVSDSESEDP-PRPQASDSESEELPKPRVSDSES-----EDPQKGPASdseaedasrHKEKPESEDSDgenkrEDSEVQN 293
Cdd:PHA03247 2976 RFRVPQPAPSrEAPASSTPPLTGHSLSRVSSWASslalhEETDPPPVS---------LKQTLWPPDDT-----EDSDADS 3041
|
170 180 190
....*....|....*....|....*....|....*....
gi 564393050 294 ESDGHADRKGLHSSDSEEEEPKRQKIDSDDDGEKEGDEK 332
Cdd:PHA03247 3042 LFDSDSERSDLEALDPLPPEPHDPFAHEPDPATPEAGAR 3080
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
101-297 |
4.11e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 43.42 E-value: 4.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 101 AESPASDSENEAVHQQGSDSEKEELLNGhaSDSEKEEGRKHAASDSETEDTLQPQGSESDSEDPPRPQASDSESEEPPKP 180
Cdd:PHA03169 43 AAKPAPPAPTTSGPQVRAVAEQGHRQTE--SDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPSPSGSAEELASGLSP 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 181 RISDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDS--------ESEDPPRPQASDSEsEELPKPRVSDSES 252
Cdd:PHA03169 121 ENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPNQQPSsflqpsheDSPEEPEPPTSEPE-PDSPGPPQSETPT 199
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 564393050 253 EDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDG 297
Cdd:PHA03169 200 SSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEPEREG 244
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
2-203 |
4.89e-04 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 43.83 E-value: 4.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 2 DSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVDRHSENETSDREDGLTKIHNGTDSENDEPSNVHASD 81
Cdd:TIGR00927 698 EIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKED 777
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 82 SESEELHRPKDSDSESEEHAESPAsdsENEAVHQQGSDSEKEELLNGHASDSEKEEGRKHAASDSETEDtlQPQGSESDS 161
Cdd:TIGR00927 778 EDEGEIQAGEDGEMKGDEGAEGKV---EHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQG--EAKQDEKGV 852
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 564393050 162 EDPPRPQASDSESEEPPKPRISDSESEELPKPRiSDSESEDP 203
Cdd:TIGR00927 853 DGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEE-EEEENEEP 893
|
|
| PRK08581 |
PRK08581 |
amidase domain-containing protein; |
2-203 |
4.89e-04 |
|
amidase domain-containing protein;
Pssm-ID: 236304 [Multi-domain] Cd Length: 619 Bit Score: 43.62 E-value: 4.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 2 DSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVDRHSENETSDREDGLTKIHNGTDSEND-EPSNVHAS 80
Cdd:PRK08581 104 INQLLTKNKYDDNYSLTTLIQNLFNLNSDISDYEQPRNSEKSTNDSNKNSDSSIKNDTDTQSSKQDKADNQkAPSSNNTK 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 81 DSESEELHRPK------DSDSESEEHAESPASDSENEAvhQQGSDSEKEELLNGHASDSEKEEGRKHAASDSETEDTLQ- 153
Cdd:PRK08581 184 PSTSNKQPNSPkptqpnQSNSQPASDDTANQKSSSKDN--QSMSDSALDSILDQYSEDAKKTQKDYASQSKKDKTETSNt 261
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 564393050 154 --PQGSESDSEDPPRPQASDSESEEPPKPRISDSESEELPKprISDSESEDP 203
Cdd:PRK08581 262 knPQLPTQDELKHKSKPAQSFENDVNQSNTRSTSLFETGPS--LSNNDDSGS 311
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
161-331 |
6.77e-04 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 42.89 E-value: 6.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 161 SEDPPRPQASDSESEEPPKPRISDSESEELPKPRISDSESEDPPRPQvsdseseeLPKPRVSDSESEDPPRPQASDSESE 240
Cdd:PRK14086 92 AGEPAPPPPHARRTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDQ--------LPTARPAYPAYQQRPEPGAWPRAAD 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 241 ELP--KPRVSDSESEDPqkgPASDSEAEDASRHKEKPESEDSDGENKREDsevQNESDGHADRKGLHSSDSEEEEPKRQK 318
Cdd:PRK14086 164 DYGwqQQRLGFPPRAPY---ASPASYAPEQERDREPYDAGRPEYDQRRRD---YDHPRPDWDRPRRDRTDRPEPPPGAGH 237
|
170
....*....|...
gi 564393050 319 IDSDDDGEKEGDE 331
Cdd:PRK14086 238 VHRGGPGPPERDD 250
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
217-448 |
6.96e-04 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 43.11 E-value: 6.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 217 PKPRVSDSESEDPPRPQASDSESEELPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESD 296
Cdd:PTZ00108 1160 SKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSS 1239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 297 GHADRKglhSSDSEEEEPKRQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKSrvISDADDSDSDVVSDKSGK 376
Cdd:PTZ00108 1240 VKRLKS---KKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGES--NGGSKPSSPTKKKVKKRL 1314
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564393050 377 REKTVASDSEEEVGKEESSVKKSEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKNE 448
Cdd:PTZ00108 1315 EGSLAALKKKKKSEKKTARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDDEDDED 1386
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
22-241 |
7.07e-04 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 43.11 E-value: 7.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 22 ERDSGSDGEDDVNEQHSGSDTGSVDRHSENETSDREDGLTKIHNGTDSENDEPSNVHASDSESEELHRPKDSDSESEEHA 101
Cdd:PTZ00108 1178 EKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDN 1257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 102 ESPASDseneavHQQGSDSEKEELLNGHASDSEKEEGRKHAASDSETEDTLQPQGSESDSEDPPRPQASDSESEEPPKPR 181
Cdd:PTZ00108 1258 DEFSSD------DLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTKKKVKKRLEGSLAALKKKKKSEKKT 1331
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 182 ISDSESEELPKPRISDSESEDPPRPQVSDSESEElpkprvsdsESEDPPRPQASDSESEE 241
Cdd:PTZ00108 1332 ARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSS---------EDDDDSEVDDSEDEDDE 1382
|
|
| ECM1 |
pfam05782 |
Extracellular matrix protein 1 (ECM1); This family consists of several eukaryotic ... |
164-275 |
9.95e-04 |
|
Extracellular matrix protein 1 (ECM1); This family consists of several eukaryotic extracellular matrix protein 1 (ECM1) sequences. ECM1 has been shown to regulate endochondral bone formation, stimulate the proliferation of endothelial cells and induce angiogenesis. Mutations in the ECM1 gene can cause lipoid proteinosis, a disorder which causes generalized thickening of skin, mucosae and certain viscera. Classical features include beaded eyelid papules and laryngeal infiltration leading to hoarseness.
Pssm-ID: 461739 Cd Length: 518 Bit Score: 42.52 E-value: 9.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 164 PPRPqasdsesEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRPQASDSESEELP 243
Cdd:pfam05782 6 PPSP-------PQTRGLPVDHPDTSQHDPPFEGQSEVQPPPSQEAIPVQEEELPPPQLPVEKKVDPPLPQEAIPLQEELP 78
|
90 100 110
....*....|....*....|....*....|...
gi 564393050 244 KPRVSDSESE-DPQKGPasDSEAEDASRHKEKP 275
Cdd:pfam05782 79 PPQLPIEQKEiDPPFPQ--QEEITPSKQREEKP 109
|
|
| MDN1 |
COG5271 |
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ... |
9-461 |
1.01e-03 |
|
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444083 [Multi-domain] Cd Length: 1028 Bit Score: 42.69 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 9 DQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVDRHSENETSDREDGLTKIHNGTDSENDEPSNVHASDSESEELH 88
Cdd:COG5271 513 ETSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAETEDATENADADETEESAD 592
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 89 RPKDSDSESEEHAESPASDSENEAVHQQGSdSEKEELLNGHASDSEKEEGRKHAASDSETEDTLQPQGSESDSEDPPRPQ 168
Cdd:COG5271 593 ESEEAEASEDEAAEEEEADDDEADADADGA-ADEEETEEEAAEDEAAEPETDASEAADEDADAETEAEASADESEEEAED 671
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 169 ASDSESEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRPQASDSESEELPKPrvS 248
Cdd:COG5271 672 ESETSSEDAEEDADAAAAEASDDEEETEEADEDAETASEEADAEEADTEADGTAEEAEEAAEEAESADEEAASLPDE--A 749
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 249 DSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLHSSDSEEEEPKRQKIDSDDDGEKE 328
Cdd:COG5271 750 DAEEEAEEAEEAEEDDADGLEEALEEEKADAEEAATDEEAEAAAEEKEKVADEDQDTDEDALLDEAEADEEEDLDGEDEE 829
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 329 GDEKVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASDSEEEVGKEESSVKKSEEKDLFGSD 408
Cdd:COG5271 830 TADEALEDIEAGIAEDDEEDDDAAAAKDVDADLDLDADLAADEHEAEEAQEAETDADADADAGEADSSGESSAAAEDDDA 909
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 564393050 409 SESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAEDSDSDD 461
Cdd:COG5271 910 AEDADSDDGANDEDDDDDAEEERKDAEEDELGAAEDDLDALALDEAGDEESDD 962
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
4-396 |
1.29e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 42.47 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 4 EYYSGDQSDDGGATPVQDERDSGSDGEDDVneqHSGSDTGSVDRHSENETSDREDGLTKIHNGTDSENDEPSNVH---AS 80
Cdd:PHA03307 6 DLYDLIEAAAEGGEFFPRPPATPGDAADDL---LSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTeapAN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 81 DSESEELHRPKDSDSESEEHAESP-----ASDSENEAVHQQGSDSEKEEllNGHASDSEKEEGRKHAASDSETEDTLQPQ 155
Cdd:PHA03307 83 ESRSTPTWSLSTLAPASPAREGSPtppgpSSPDPPPPTPPPASPPPSPA--PDLSEMLRPVGSPGPPPAASPPAAGASPA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 156 GSESDSEDPP---RPQASDSESEEPPkprisDSESEELPKPRISDSESEDPPRPQVSDSESEELPKPRVSDSESEDPPRP 232
Cdd:PHA03307 161 AVASDAASSRqaaLPLSSPEETARAP-----SSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGAS 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 233 QASDSESEELPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLHSS---DS 309
Cdd:PHA03307 236 SSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSsprAS 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 310 EEEEPkrqkiDSDDDGEKEGDEKVAKRKAAVL---------SDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKT 380
Cdd:PHA03307 316 SSSSS-----SRESSSSSTSSSSESSRGAAVSpgpspsrspSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRA 390
|
410
....*....|....*.
gi 564393050 381 VASDSEEEVGKEESSV 396
Cdd:PHA03307 391 RAAVAGRARRRDATGR 406
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
71-260 |
1.36e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 42.38 E-value: 1.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 71 NDEPSNVHASDSESEELHRpkdsDSESEEHAESPASDSENEAVHQQGSDSEKEEllnghaSDSEKEEGRKHAASDSETED 150
Cdd:PRK10263 643 NQYDSGDQYNDDEIDAMQQ----DELARQFAQTQQQRYGEQYQHDVPVNAEDAD------AAAEAELARQFAQTQQQRYS 712
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 151 TLQPQGSESDSED-----PPRPQASDSESE-----------EPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSESE 214
Cdd:PRK10263 713 GEQPAGANPFSLDdfefsPMKALLDDGPHEplftpivepvqQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQ 792
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 564393050 215 ELPKPRVSDSESEDPPRPQASDSESEELPKPRVSDSESEDPQKGPA 260
Cdd:PRK10263 793 QPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVA 838
|
|
| 2A1904 |
TIGR00927 |
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ... |
146-415 |
1.61e-03 |
|
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273344 [Multi-domain] Cd Length: 1096 Bit Score: 41.90 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 146 SETEDTLQPQGSESDSEDP---PRPQASDSESEEPPKPR-ISDSESE-ELPKPRISDSESEDPPRPQVSDSESEELPKPR 220
Cdd:TIGR00927 636 AEAEHTGERTGEEGERPTEaegENGEESGGEAEQEGETEtKGENESEgEIPAERKGEQEGEGEIEAKEADHKGETEAEEV 715
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 221 VSDSESEDPPRPQASDSESEElpkprvsdsESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHAD 300
Cdd:TIGR00927 716 EHEGETEAEGTEDEGEIETGE---------EGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQAG 786
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 301 RKGLHSSDSEEEEPKRQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKt 380
Cdd:TIGR00927 787 EDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVDGGGGSDGGDSEE- 865
|
250 260 270
....*....|....*....|....*....|....*
gi 564393050 381 vasDSEEEVGKEESSVKKSEEKdlfgsDSESGNEE 415
Cdd:TIGR00927 866 ---EEEEEEEEEEEEEEEEEEE-----EEEEENEE 892
|
|
| AF-4 |
pfam05110 |
AF-4 proto-oncoprotein N-terminal region; This family consists of AF4 (Proto-oncogene AF4) and ... |
144-238 |
2.13e-03 |
|
AF-4 proto-oncoprotein N-terminal region; This family consists of AF4 (Proto-oncogene AF4) and FMR2 (Fragile X E mental retardation syndrome) nuclear proteins. These proteins have been linked to human diseases such as acute lymphoblastic leukaemia and mental retardation. The family also contains a Drosophila AF4 protein homolog Lilliputian which contains an AT-hook domain. Lilliputian represents a novel pair-rule gene that acts in cytoskeleton regulation, segmentation and morphogenesis in Drosophila.
Pssm-ID: 461550 [Multi-domain] Cd Length: 514 Bit Score: 41.26 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 144 SDSETEDTLQPQGSESDSEDPPRPQASDSESEEPPKPRISDSESEelpkpriSDSESEDPprpqvSDSESEElpkpRVSD 223
Cdd:pfam05110 422 SSSEDSDDDQAPEKPPPSSAPPSAPQSQPNSVASAHSSSGESGSS-------SDSESSSE-----SDSESES----SSSD 485
|
90
....*....|....*
gi 564393050 224 SESEDPPRPQASDSE 238
Cdd:pfam05110 486 SEANEPPRSATPEPE 500
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
98-296 |
2.91e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.12 E-value: 2.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 98 EEHAESPASDSENEAV--HQQGSDSEKEELLNGHASDSEKEEGRKHAASDSETEDTLQPQ----GSESDSEDPPRPQASD 171
Cdd:PRK07764 610 EEAARPAAPAAPAAPAapAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWpakaGGAAPAAPPPAPAPAA 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 172 SESEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSeseelpkprvSDSESEDPPRPQASDSESEELPKPRVSDSE 251
Cdd:PRK07764 690 PAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGAS----------APSPAADDPVPLPPEPDDPPDPAGAPAQPP 759
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 564393050 252 SEDPQKGPASDSEAEDASRHKEKPESED----SDGENKREDSEVQNESD 296
Cdd:PRK07764 760 PPPAPAPAAAPAAAPPPSPPSEEEEMAEddapSMDDEDRRDAEEVAMEL 808
|
|
| PHA02664 |
PHA02664 |
hypothetical protein; Provisional |
232-341 |
3.00e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 177447 Cd Length: 534 Bit Score: 40.75 E-value: 3.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 232 PQASDSESEELPKPrvsDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADrkglhSSDSEE 311
Cdd:PHA02664 424 PADQDVEAEAHDEF---DQDPGAPAHADRADSDEDDMDEQESGDERADGEDDSDSSYSYSTTSSEDESD-----SADDSW 495
|
90 100 110
....*....|....*....|....*....|
gi 564393050 312 EEPKRQKIDSDDDGEKEGDEKVAKRKAAVL 341
Cdd:PHA02664 496 GDESDSGIEHDDGGVGQAIEEEEEEERAVL 525
|
|
| PRK08581 |
PRK08581 |
amidase domain-containing protein; |
19-257 |
3.67e-03 |
|
amidase domain-containing protein;
Pssm-ID: 236304 [Multi-domain] Cd Length: 619 Bit Score: 40.54 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 19 VQDERDSGSDGEDDVNEQHSGSDTGSVDRHSE--NETSDREDGLTKIHNGTDSEND-EPSNVHASDSESEELHRPKDSDS 95
Cdd:PRK08581 52 SKDTSSKDTDKADNNNTSNQDNNDKKFSTIDSstSDSNNIIDFIYKNLPQTNINQLlTKNKYDDNYSLTTLIQNLFNLNS 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 96 ESEEHAESPASDSENEAVHQQGSDSEKEellNGHASDSEKEEGRKHAASDSeTEDTLQPQGSESDSEDPPRPQASDSESE 175
Cdd:PRK08581 132 DISDYEQPRNSEKSTNDSNKNSDSSIKN---DTDTQSSKQDKADNQKAPSS-NNTKPSTSNKQPNSPKPTQPNQSNSQPA 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 176 EPPKPRISDSESE-----ELPKPRISDSESEDPPR-PQVSDSESEelpKPRVSDSESEDPPRPQASDSESEELPKPrvsD 249
Cdd:PRK08581 208 SDDTANQKSSSKDnqsmsDSALDSILDQYSEDAKKtQKDYASQSK---KDKTETSNTKNPQLPTQDELKHKSKPAQ---S 281
|
....*...
gi 564393050 250 SESEDPQK 257
Cdd:PRK08581 282 FENDVNQS 289
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
149-316 |
3.84e-03 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 40.35 E-value: 3.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 149 EDTLQPQGSESDSEDPPRPQASDS--------ESEEPP----KPRISDSESEELpKPRISDSESEDPPRPQVSDSESEEL 216
Cdd:PRK13108 280 EAPGALRGSEYVVDEALEREPAELaaaavasaASAVGPvgpgEPNQPDDVAEAV-KAEVAEVTDEVAAESVVQVADRDGE 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 217 PKPRVSDSESEDPPRPQASDSESEELPKPRVSDS-ESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNES 295
Cdd:PRK13108 359 STPAVEETSEADIEREQPGDLAGQAPAAHQVDAEaASAAPEEPAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPG 438
|
170 180
....*....|....*....|.
gi 564393050 296 DGHADRKGLHSSDSEEEEPKR 316
Cdd:PRK13108 439 DDPAEPDGIRRQDDFSSRRRR 459
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
128-318 |
4.20e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 40.34 E-value: 4.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 128 GHASDSEKEEGRKHAASDSETEDTLQPQGSESDSEDPPRPQASDSESEEPPKPRISDSESEELPKPRISDSESEDPPRPQ 207
Cdd:PHA03169 55 GPQVRAVAEQGHRQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPASH 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 208 VSDSESEELPKPRVSDSESEDPPRPQASDSE------SEELPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSD 281
Cdd:PHA03169 135 SPPPSPPSHPGPHEPAPPESHNPSPNQQPSSflqpshEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEP 214
|
170 180 190
....*....|....*....|....*....|....*..
gi 564393050 282 GENKREDSEVQNESDGHADRKglHSSDSEEEEPKRQK 318
Cdd:PHA03169 215 QSPTPQQAPSPNTQQAVEHED--EPTEPEREGPPFPG 249
|
|
| MDN1 |
COG5271 |
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal ... |
9-461 |
6.17e-03 |
|
Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444083 [Multi-domain] Cd Length: 1028 Bit Score: 40.00 E-value: 6.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 9 DQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVDRHSENETSDRE---DGLTKIHNGTDSENDEPSNVHASDSESE 85
Cdd:COG5271 431 DESTDVTSAEDDIATDEEADSLADEEEEAEAELDTEEDTESAEEDADGDeatDEDDASDDGDEEEAEEDAEAEADSDELT 510
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 86 ELHRPKDSDSESEEHAESPASDSENEAVHQQGSDSEKEELLNGHASDSEKEEGRKHAASDSETEDTLQPQGSESDSEDPP 165
Cdd:COG5271 511 AEETSADDGADTDAAADPEDSDEDALEDETEGEENAPGSDQDADETDEPEATAEEDEPDEAEAETEDATENADADETEES 590
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 166 RPQASDSE-------SEEPPKPRISDSESEELPKPRISDSESEDPPRPQVSDSESE--------ELPKPRVSDSESEDPP 230
Cdd:COG5271 591 ADESEEAEasedeaaEEEEADDDEADADADGAADEEETEEEAAEDEAAEPETDASEaadedadaETEAEASADESEEEAE 670
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 231 RPQASDSESEELPKPRVSDSESEDPQKGPASDSEAEDASRHKEKPESEDSDGENKREDSEVQNESDGHADRKGLHSSDSE 310
Cdd:COG5271 671 DESETSSEDAEEDADAAAAEASDDEEETEEADEDAETASEEADAEEADTEADGTAEEAEEAAEEAESADEEAASLPDEAD 750
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 311 EEEPKRQKIDSDDDGEKEGDEKVAKRKAAVLSDSEDEDKASAAKKSRVISDADDSDSDVVSDKSGKREKTVASDSEEEVG 390
Cdd:COG5271 751 AEEEAEEAEEAEEDDADGLEEALEEEKADAEEAATDEEAEAAAEEKEKVADEDQDTDEDALLDEAEADEEEDLDGEDEET 830
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564393050 391 KEESSVKKSEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKNETQLKEAEDSDSDD 461
Cdd:COG5271 831 ADEALEDIEAGIAEDDEEDDDAAAAKDVDADLDLDADLAADEHEAEEAQEAETDADADADAGEADSSGESS 901
|
|
| Herpes_LMP1 |
pfam05297 |
Herpesvirus latent membrane protein 1 (LMP1); This family consists of several latent membrane ... |
115-271 |
8.54e-03 |
|
Herpesvirus latent membrane protein 1 (LMP1); This family consists of several latent membrane protein 1 or LMP1s mostly from Epstein-Barr virus. LMP1 of EBV is a 62-65 kDa plasma membrane protein possessing six membrane spanning regions, a short cytoplasmic N-terminus and a long cytoplasmic carboxy tail of 200 amino acids. EBV latent membrane protein 1 (LMP1) is essential for EBV-mediated transformation and has been associated with several cases of malignancies. EBV-like viruses in Cynomolgus monkeys (Macaca fascicularis) have been associated with high lymphoma rates in immunosuppressed monkeys
Pssm-ID: 283060 Cd Length: 386 Bit Score: 39.24 E-value: 8.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 115 QQGSDSekeellNGHASDSEKEEGRKH----AASDSE---TEDTLQPQGSESDSedPPRPQASDSESeePPKPRISDSES 187
Cdd:pfam05297 205 QQATDD------SGHESDSNSNEGRHHllvsGAGDGPplcSQNLGAPGGGPDNG--PQDPDNTDDNG--PQDPDNTDDNG 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 188 EELPKPRisDSESEDPPRPQVSDSESEELPkprvsdsesEDPPRPQASDSESEELPKPRVSDS-ESEDPQKGPASDSEAE 266
Cdd:pfam05297 275 PHDPLPQ--DPDNTDDNGPQDPDNTADNGP---------HDPLPHNPSDSAGNDGGPPNLTEEvENKGGDQGPPLMTDGG 343
|
....*
gi 564393050 267 DASRH 271
Cdd:pfam05297 344 GGHSH 348
|
|
| CobT2 |
COG4547 |
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; ... |
79-180 |
9.41e-03 |
|
Cobalamin biosynthesis cobaltochelatase CobT subunit [Coenzyme transport and metabolism]; Cobalamin biosynthesis cobaltochelatase CobT subunit is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 443611 [Multi-domain] Cd Length: 608 Bit Score: 39.39 E-value: 9.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564393050 79 ASDSESEELHRPKDSDSESEEHAESPASDSENEAVHQQGSDSEKEELLNGHASDSEKEEGRkhAASDSETEDTLQPQGSE 158
Cdd:COG4547 208 AEELGEDEDEEDEDDEDDSGEQEEDEEDGEDEDEESDEGAEAEDAEASGDDAEEGESEAAE--AESDEMAEEAEGEDSEE 285
|
90 100
....*....|....*....|..
gi 564393050 159 SDSEDPPRPQASDSESEEPPKP 180
Cdd:COG4547 286 PGEPWRPNAPPPDDPADPDYKV 307
|
|
| |
