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Conserved domains on  [gi|564376925|ref|XP_006248442|]
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golgin subfamily B member 1 isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 720-1623 1.88e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 1.88e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   720 FKESAEEARSTLtavcEERDQLLYRVKelDVLGELRAQVRELETSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaks 799
Cdd:TIGR02168  170 YKERRKETERKL----ERTRENLDRLE--DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------ 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   800 kDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKK 879
Cdd:TIGR02168  238 -REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   880 DVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDsgaesspkhgphessa 959
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELA----EELAELEEKLEELKEELESLEAELEELEAELEELESRLEE---------------- 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   960 qepvckdaLQQELEWLRKESEQRKRKLQAALISRKELLQKVSKLEEELAKVREEstkdslRESEKRELEEDSKNKddpek 1039
Cdd:TIGR02168  377 --------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQE------IEELLKKLEEAELKE----- 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1040 ygtsewrelevsLRLTISEKEVELEGIRRDLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEEITENQATIQKFitgt 1119
Cdd:TIGR02168  438 ------------LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL---- 501

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1120 MDAGDGDSAVKEtsvsspPRAGGGEHWKPELEGKIVDLEKEK---TQLQKKLQEALISRKAILKKAQEkekHLKeelkeq 1196
Cdd:TIGR02168  502 EGFSEGVKALLK------NQSGLSGILGVLSELISVDEGYEAaieAALGGRLQAVVVENLNAAKKAIA---FLK------ 566

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1197 kdayrhlqeqfdgqskenENIAARLRQLQAKESTDQQLPGTGQQEPTHGSEGLSLegtepasESDLHAAQPSHPGETATL 1276
Cdd:TIGR02168  567 ------------------QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGV-------AKDLVKFDPKLRKALSYL 621

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1277 QATVSVAQIQDQLKEIEVEKEELELKIS-----------------STTSELTKKSEEVLLLQEQINEQGLEIQNLKAASH 1339
Cdd:TIGR02168  622 LGGVLVVDDLDNALELAKKLRPGYRIVTldgdlvrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALA 701

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1340 EAKAHTEQLKQELESSQLKIADLEH-LKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALH 1418
Cdd:TIGR02168  702 ELRKELEELEEELEQLRKELEELSRqISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1419 T---QLEMQAKEHEERLKQVQVEICELKKQPKELEEE----SKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAV 1491
Cdd:TIGR02168  782 AeieELEAQIEQLKEELKALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1492 EHLTKSLADVESQVSVQNQEKDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESV 1571
Cdd:TIGR02168  862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|..
gi 564376925  1572 RcSKIAEstewqekhkELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQE 1623
Cdd:TIGR02168  942 Q-ERLSE---------EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1876-2632 2.04e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.04e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1876 QQIQEELSRVTKLKETAEEEKDDLEERLMN---QLAELNGSIGNYYQDVTDAQikneqleSEMQNLKRCVSELEEEKQQL 1952
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQEleeKLEELRLEVSELEEEIEELQ-------KELYALANEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1953 VKEKTKVESEIrKEYMEKIQGAQKgpgskiHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKD 2032
Cdd:TIGR02168  308 RERLANLERQL-EELEAQLEELES------KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2033 LDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHR 2112
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2113 KEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWEQRF 2192
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGL 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2193 GDAIQTKEEEVRLKEENCTALKDQLRQmtiHMEelKITVSRLEHDKEIWESKAQTELQH------QQKAYDKLQEENKEL 2266
Cdd:TIGR02168  519 SGILGVLSELISVDEGYEAAIEAALGG---RLQ--AVVVENLNAAKKAIAFLKQNELGRvtflplDSIKGTEIQGNDREI 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2267 MSQLEEAGQLYHDSKNELTKLESELKSLKDQS---TDLKNSLEK------------------------------------ 2307
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELakklrpgyrivtldgdlvrpggvitggsaktnssil 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2308 CREHE-NNLEGIIKQQEADIQNCKFNCEQLETDLTASRELTTRLHDEINVKEQKIISLLS--GKEEAIQVAIAELHQQHS 2384
Cdd:TIGR02168  674 ERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKdlARLEAEVEQLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2385 KEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERh 2464
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR- 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2465 lsvilekdelIQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVITIKDSQQRQLLEAQLQQnKELRN 2544
Cdd:TIGR02168  833 ----------IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL-EELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2545 ECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALheegalavYHAQLRVREEEVQKLTAALSSSQKR 2624
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE--------YSLTLEEAEALENKIEDDEEEARRR 973


                   ....*...
gi 564376925  2625 TVDLQEEL 2632
Cdd:TIGR02168  974 LKRLENKI 981
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 189-947 5.16e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 5.16e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   189 MRQKLQEKEELIGALQTQLS--QTQAEQAaqlssmQQVVREKDARFETQVRLHEDELLQLVTQSDvetEVQQKLRVMQRK 266
Cdd:TIGR02168  184 TRENLDRLEDILNELERQLKslERQAEKA------ERYKELKAELRELELALLVLRLEELREELE---ELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   267 LEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQLQlleaEHSTLRNTMEAERQESKILMEKVELEMAERKEELYQLQG 346
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQKELY----ALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   347 QLERAGQAQAELEMQYGTLQQRHETEMEEKTACISLLQKNEQELQSACDALKEENSKLLQEQQEQAAKSAQaLQQLEDEL 426
Cdd:TIGR02168  331 KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE-IERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   427 QQKSKEISQFV-NKPNLEKHETSSQTSLPDVYNEGVQAVMEESVASLQKRVLELENEKGALLLSSLELEELRAENEKLCS 505
Cdd:TIGR02168  410 ERLEDRRERLQqEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   506 RITLLEA--QNRAGEADGmvcevstAGIALLNRSDS-----------STEESGQDVLENTFSqkhKELSVLLVEMKEAQ- 571
Cdd:TIGR02168  490 RLDSLERlqENLEGFSEG-------VKALLKNQSGLsgilgvlseliSVDEGYEAAIEAALG---GRLQAVVVENLNAAk 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   572 EEIAFLKSQLQGKR------PEGDYEVLDRKEVQMMESEGLPSVTARDVLCAPRDKNSVPA-------VEGEQAGMRDQH 638
Cdd:TIGR02168  560 KAIAFLKQNELGRVtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvVDDLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   639 GTLEAGPLNDTGMELNSPQPDGVDKSLSAPHVCLCHQGELERLKTQVLELETSLHTAkethEKNLSEKAKEISSLTQLTK 718
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   719 EFKESAEEARSTLTAVCEErdqllyrvkeldvLGELRAQVRELETSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAK 798
Cdd:TIGR02168  716 QLRKELEELSRQISALRKD-------------LARLEAEVEQLEERIAQLSKEL----TELEAEIEELEERLEEAEEELA 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   799 SKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKK 878
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925   879 KDVETLQQTIQEKDQQVTELSF---SMTEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAE 947
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR 930
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 2319-3068 1.90e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.90e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2319 IKQQEADIQNCKFNCEQLETDLTASRELTTRLHDEINVKEqKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLS--- 2395
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREYEGYELLKEKEALERQKEAIERQLAsle 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2396 -QEEEENLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEErhlsvilEKDEL 2474
Cdd:TIGR02169  251 eELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE-------DAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2475 IQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVitikdsqqRQLLEAQLQQNKELRNECVKLEGRLK 2554
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDL--------RAELEEVDKEFAETRDELKDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2555 GSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHE-----EGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQ 2629
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAkinelEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2630 EELVCVQKEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAEER--VAELARDLVEMEQKLLTvtkenkdltAQIQAFG 2707
Cdd:TIGR02169  476 EEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIqgVHGTVAQLGSVGERYAT---------AIEVAAG 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2708 KSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGRQDLGRESDVLSQAAF------------------------PLTT 2763
Cdd:TIGR02169  547 NRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVigfavdlvefdpkyepafkyvfgdTLVV 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2764 SENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSFTKAMTSLQNERDHLWNELEKFRKSEEGKQrsaaPSAASSPA 2843
Cdd:TIGR02169  627 EDIEAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ----SELRRIEN 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2844 EVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMNQEITELRplkAQLQESQDQTKALQMMKEELRQENLSWQHELHQLRV 2923
Cdd:TIGR02169  703 RLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE---EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2924 EKNSWELHERRMKEQYLMAISDK-DQQLGHLQNLLRELRSSSQTQILPTQYQRQASsgtsaaldgsQNLVYETDCLRTQL 3002
Cdd:TIGR02169  780 ALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI----------QELQEQRIDLKEQI 849

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564376925  3003 NDSLKEIHQKELRIQQLNSKFSQLLEEKNILSTQLRDANQSLRDSQHHYSNLFNHCAILERQVQQL 3068
Cdd:TIGR02169  850 KSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
YhaN super family cl34808
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1561-2033 8.62e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


The actual alignment was detected with superfamily member COG4717:

Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 8.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1561 KEKLMKELESVRcSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQ--EVYAKLRSAESDKRER 1638
Cdd:COG4717    66 PELNLKELKELE-EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAEL 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1639 EKQLQDAeqemeemkekmrkfaKSKQQKILELEEENDRLRAEAQPVggANESMEALLSSNASLKEELERITLEYKTLSKE 1718
Cdd:COG4717   145 PERLEEL---------------EERLEELRELEEELEELEAELAEL--QEELEELLEQLSLATEEELQDLAEELEELQQR 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1719 FEALMAEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTeAVVGKSQEQDSLSENAKLEDAEATLLANSA 1798
Cdd:COG4717   208 LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAA-ALLALLGLGGSLLSLILTIAGVLFLVLGLL 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1799 KPGVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQI 1878
Cdd:COG4717   287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1879 QEELSRVTKLKETAEEEKDDLEERLM---------NQLAELNGSIGNYYQDVTD--AQIKNEQLESEMQNLKRCVSELEE 1947
Cdd:COG4717   367 ELEQEIAALLAEAGVEDEEELRAALEqaeeyqelkEELEELEEQLEELLGELEEllEALDEEELEEELEELEEELEELEE 446

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1948 EKQQLVKEKTKVESEIrkEYMEKiqgaqkgpgskihAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHT 2027
Cdd:COG4717   447 ELEELREELAELEAEL--EQLEE-------------DGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYRE 511


                  ....*.
gi 564376925 2028 ESQKDL 2033
Cdd:COG4717   512 ERLPPV 517
PRK12704 super family cl36166
phosphodiesterase; Provisional
 63-181 3.76e-03

phosphodiesterase; Provisional


The actual alignment was detected with superfamily member PRK12704:

Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 3.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   63 LKDIISKQDAQLQQK-DEALQEEKKGAESKIKKIKLHAKAKITSLNKQIE-ELKTQGGAASPPE---VQAEE-LSKHDKS 136
Cdd:PRK12704   25 RKKIAEAKIKEAEEEaKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEkELRERRNELQKLEkrlLQKEEnLDRKLEL 104

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 564376925  137 STEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSA 181
Cdd:PRK12704  105 LEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISG 149
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 720-1623 1.88e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 1.88e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   720 FKESAEEARSTLtavcEERDQLLYRVKelDVLGELRAQVRELETSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaks 799
Cdd:TIGR02168  170 YKERRKETERKL----ERTRENLDRLE--DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------ 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   800 kDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKK 879
Cdd:TIGR02168  238 -REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   880 DVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDsgaesspkhgphessa 959
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELA----EELAELEEKLEELKEELESLEAELEELEAELEELESRLEE---------------- 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   960 qepvckdaLQQELEWLRKESEQRKRKLQAALISRKELLQKVSKLEEELAKVREEstkdslRESEKRELEEDSKNKddpek 1039
Cdd:TIGR02168  377 --------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQE------IEELLKKLEEAELKE----- 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1040 ygtsewrelevsLRLTISEKEVELEGIRRDLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEEITENQATIQKFitgt 1119
Cdd:TIGR02168  438 ------------LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL---- 501

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1120 MDAGDGDSAVKEtsvsspPRAGGGEHWKPELEGKIVDLEKEK---TQLQKKLQEALISRKAILKKAQEkekHLKeelkeq 1196
Cdd:TIGR02168  502 EGFSEGVKALLK------NQSGLSGILGVLSELISVDEGYEAaieAALGGRLQAVVVENLNAAKKAIA---FLK------ 566

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1197 kdayrhlqeqfdgqskenENIAARLRQLQAKESTDQQLPGTGQQEPTHGSEGLSLegtepasESDLHAAQPSHPGETATL 1276
Cdd:TIGR02168  567 ------------------QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGV-------AKDLVKFDPKLRKALSYL 621

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1277 QATVSVAQIQDQLKEIEVEKEELELKIS-----------------STTSELTKKSEEVLLLQEQINEQGLEIQNLKAASH 1339
Cdd:TIGR02168  622 LGGVLVVDDLDNALELAKKLRPGYRIVTldgdlvrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALA 701

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1340 EAKAHTEQLKQELESSQLKIADLEH-LKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALH 1418
Cdd:TIGR02168  702 ELRKELEELEEELEQLRKELEELSRqISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1419 T---QLEMQAKEHEERLKQVQVEICELKKQPKELEEE----SKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAV 1491
Cdd:TIGR02168  782 AeieELEAQIEQLKEELKALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1492 EHLTKSLADVESQVSVQNQEKDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESV 1571
Cdd:TIGR02168  862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|..
gi 564376925  1572 RcSKIAEstewqekhkELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQE 1623
Cdd:TIGR02168  942 Q-ERLSE---------EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1876-2632 2.04e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.04e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1876 QQIQEELSRVTKLKETAEEEKDDLEERLMN---QLAELNGSIGNYYQDVTDAQikneqleSEMQNLKRCVSELEEEKQQL 1952
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQEleeKLEELRLEVSELEEEIEELQ-------KELYALANEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1953 VKEKTKVESEIrKEYMEKIQGAQKgpgskiHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKD 2032
Cdd:TIGR02168  308 RERLANLERQL-EELEAQLEELES------KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2033 LDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHR 2112
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2113 KEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWEQRF 2192
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGL 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2193 GDAIQTKEEEVRLKEENCTALKDQLRQmtiHMEelKITVSRLEHDKEIWESKAQTELQH------QQKAYDKLQEENKEL 2266
Cdd:TIGR02168  519 SGILGVLSELISVDEGYEAAIEAALGG---RLQ--AVVVENLNAAKKAIAFLKQNELGRvtflplDSIKGTEIQGNDREI 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2267 MSQLEEAGQLYHDSKNELTKLESELKSLKDQS---TDLKNSLEK------------------------------------ 2307
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELakklrpgyrivtldgdlvrpggvitggsaktnssil 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2308 CREHE-NNLEGIIKQQEADIQNCKFNCEQLETDLTASRELTTRLHDEINVKEQKIISLLS--GKEEAIQVAIAELHQQHS 2384
Cdd:TIGR02168  674 ERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKdlARLEAEVEQLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2385 KEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERh 2464
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR- 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2465 lsvilekdelIQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVITIKDSQQRQLLEAQLQQnKELRN 2544
Cdd:TIGR02168  833 ----------IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL-EELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2545 ECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALheegalavYHAQLRVREEEVQKLTAALSSSQKR 2624
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE--------YSLTLEEAEALENKIEDDEEEARRR 973


                   ....*...
gi 564376925  2625 TVDLQEEL 2632
Cdd:TIGR02168  974 LKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 189-947 5.16e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 5.16e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   189 MRQKLQEKEELIGALQTQLS--QTQAEQAaqlssmQQVVREKDARFETQVRLHEDELLQLVTQSDvetEVQQKLRVMQRK 266
Cdd:TIGR02168  184 TRENLDRLEDILNELERQLKslERQAEKA------ERYKELKAELRELELALLVLRLEELREELE---ELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   267 LEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQLQlleaEHSTLRNTMEAERQESKILMEKVELEMAERKEELYQLQG 346
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQKELY----ALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   347 QLERAGQAQAELEMQYGTLQQRHETEMEEKTACISLLQKNEQELQSACDALKEENSKLLQEQQEQAAKSAQaLQQLEDEL 426
Cdd:TIGR02168  331 KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE-IERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   427 QQKSKEISQFV-NKPNLEKHETSSQTSLPDVYNEGVQAVMEESVASLQKRVLELENEKGALLLSSLELEELRAENEKLCS 505
Cdd:TIGR02168  410 ERLEDRRERLQqEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   506 RITLLEA--QNRAGEADGmvcevstAGIALLNRSDS-----------STEESGQDVLENTFSqkhKELSVLLVEMKEAQ- 571
Cdd:TIGR02168  490 RLDSLERlqENLEGFSEG-------VKALLKNQSGLsgilgvlseliSVDEGYEAAIEAALG---GRLQAVVVENLNAAk 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   572 EEIAFLKSQLQGKR------PEGDYEVLDRKEVQMMESEGLPSVTARDVLCAPRDKNSVPA-------VEGEQAGMRDQH 638
Cdd:TIGR02168  560 KAIAFLKQNELGRVtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvVDDLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   639 GTLEAGPLNDTGMELNSPQPDGVDKSLSAPHVCLCHQGELERLKTQVLELETSLHTAkethEKNLSEKAKEISSLTQLTK 718
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   719 EFKESAEEARSTLTAVCEErdqllyrvkeldvLGELRAQVRELETSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAK 798
Cdd:TIGR02168  716 QLRKELEELSRQISALRKD-------------LARLEAEVEQLEERIAQLSKEL----TELEAEIEELEERLEEAEEELA 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   799 SKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKK 878
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925   879 KDVETLQQTIQEKDQQVTELSF---SMTEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAE 947
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR 930
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1347-1914 7.07e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 7.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1347 QLKQELESSQLKIAdLEHLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAK 1426
Cdd:COG1196   217 ELKEELKELEAELL-LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1427 EHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSLADVESQVS 1506
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1507 VQNQEKDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESVRcskiAESTEWQEKH 1586
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE----EALEEAAEEE 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1587 KELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQK 1666
Cdd:COG1196   452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1667 ILELEEENDRLRAEAQPVGGANESMEALLSSNASLKEE-LERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQE- 1744
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREa 611

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1745 --------------------LKQASLETTEKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKPGVSE 1804
Cdd:COG1196   612 daryyvlgdtllgrtlvaarLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1805 TFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSR 1884
Cdd:COG1196   692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 564376925 1885 VTKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1914
Cdd:COG1196   772 LEREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1728-2297 1.35e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 1.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1728 TLSEETRNLKLQVEAQELKQASLETTEKSDEpKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKpgvSETFS 1807
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELEAELEELEAE-LEELEAELEELEAELAELEAELEELRLELEELELELEEAQ---AEEYE 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1808 SHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTK 1887
Cdd:COG1196   293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1888 LKETAEEEKDDLEERLMNQLAELNgsigNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEY 1967
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAA----ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1968 MEKIQGAQKgpgsKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAVEHH 2047
Cdd:COG1196   449 EEEAELEEE----EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2048 KKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEK-----L 2122
Cdd:COG1196   525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGaavdlV 604

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2123 DALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWEQRFGDAIQTKEEE 2202
Cdd:COG1196   605 ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2203 VRLKEENCTALKDQLRQMtihmEELKITVSRLEHDKEIWESKAQTELQHQQKAYDKLQEENKELMSQLEEAGQLYHDSKN 2282
Cdd:COG1196   685 AERLAEEELELEEALLAE----EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760

                         570
                  ....*....|....*
gi 564376925 2283 ELTKLESELKSLKDQ 2297
Cdd:COG1196   761 DLEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 61-582 1.57e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 1.57e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   61 LELKDIISKQDAQLQ-QKDEALQEEKKGAESKIKKIKL---HAKAKITSLNKQIEELKTQGGAASppevqaEELSKHDKS 136
Cdd:COG1196   216 RELKEELKELEAELLlLKLRELEAELEELEAELEELEAeleELEAELAELEAELEELRLELEELE------LELEEAQAE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  137 STEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEKEELIGALQTQLSQTQAEQAA 216
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  217 QLSSMQQVVREKDARFETQVRLhEDELLQLVTQsdvETEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQ 296
Cdd:COG1196   370 AEAELAEAEEELEELAEELLEA-LRAAAELAAQ---LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  297 DLSQQLQLLEAEHSTLRNTMEAERQESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEmqyGTLQQRHETEMEEK 376
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE---GVKAALLLAGLRGL 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  377 TACISLLQKNEQELQSACDALkeenskLLQEQQEQAAKSAQALQQLEDELQQKSKEISQFVNKPNLEKHETSSQTSLPDV 456
Cdd:COG1196   523 AGAVAVLIGVEAAYEAALEAA------LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA 596

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  457 YNEGVQAVMEESVASLQKRVLELENEKGALLLSSLELEELRAEnEKLCSRITLLEAQNRAGEADGMvcevSTAGIALLNR 536
Cdd:COG1196   597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA-VTLAGRLREVTLEGEGGSAGGS----LTGGSRRELL 671

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 564376925  537 SDSSTEESGQDVLENTFSQKHKELSVLLVEMKEAQEEIAFLKSQLQ 582
Cdd:COG1196   672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717
PTZ00121 PTZ00121
MAEBL; Provisional
 707-1489 3.90e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.87  E-value: 3.90e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  707 AKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLYRVKELDvlgelraQVRELEtslaEAEKQRgldyESQRAQHNLL 786
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAE-------DARKAE----EARKAE----DARKAEEARK 1147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  787 TEQIHSLSIEAKSKDV-KIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKeMEELSQALSQKEL 865
Cdd:PTZ00121 1148 AEDAKRVEIARKAEDArKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERK-AEEARKAEDAKKA 1226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  866 EIAQMDQlllEKKKDVETLQQTiqEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQlslLSRAEGAKKEQvEDSG 945
Cdd:PTZ00121 1227 EAVKKAE---EAKKDAEEAKKA--EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE---LKKAEEKKKAD-EAKK 1297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  946 AESSPKHGPHESSAQEPVCKDALQQELEWLRKESEQRKRKLQAAlisrkellqkvsKLEEELAKVREESTKDSLRESEKR 1025
Cdd:PTZ00121 1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEA------------KKAAEAAKAEAEAAADEAEAAEEK 1365

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1026 ELEEDSKNKDDPEKYGTSEWRELEVSLRLTISEKEVELEGIRRDLKEKAAAEEELQALVQRMTQdlqnkTKQIDLLQEEI 1105
Cdd:PTZ00121 1366 AEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEE-----KKKADEAKKKA 1440

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1106 TENQATiqkfitgtmdagdgdsavKETSVSSPPRAGGGEHWKPELEGKIVDLEKEKTQLQKKLQEALISRKAILKKAQEK 1185
Cdd:PTZ00121 1441 EEAKKA------------------DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1186 EKhlKEELKEQKDAYRHLQEQFDGQSKENENIAARLRQLQAKESTDQQLPGTGQQEPTHGSEGLSLEGTEPASESDLHAA 1265
Cdd:PTZ00121 1503 KK--AAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMAL 1580

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1266 QPSHPGETATLQATVSVAQIQDQLKEIEVEKEELELKISSTTSELTKKSEE---VLLLQEQINEQGLEIQNLKAASHEAK 1342
Cdd:PTZ00121 1581 RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEkkkVEQLKKKEAEEKKKAEELKKAEEENK 1660

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1343 AHTEQLKQELESSQLKIADLEHlktlQPELETLQKHVGQKEEEVSYLVGQL--GEKEQTLTTVQTEMEEQERLIKAlhTQ 1420
Cdd:PTZ00121 1661 IKAAEEAKKAEEDKKKAEEAKK----AEEDEKKAAEALKKEAEEAKKAEELkkKEAEEKKKAEELKKAEEENKIKA--EE 1734

                         730       740       750       760       770       780
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564376925 1421 LEMQAKEHEERLKQVQVEICElKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARD 1489
Cdd:PTZ00121 1735 AKKEAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1320-1762 1.41e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.37  E-value: 1.41e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1320 LQEQINEQGLEIQNLKAASHEAKAHTE-QLKQELESSQLKIADLEHLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQ 1398
Cdd:pfam15921  417 LRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSER 496

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1399 TLTTVQTEMEEQERLIKALHTQLEMQAKEHEERLKQVQveicelkkqpkELEEESKAKQQLQRKLQAALISRKEALKENK 1478
Cdd:pfam15921  497 TVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ-----------HLKNEGDHLRNVQTECEALKLQMAEKDKVIE 565

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1479 SLQEQLSSARDAVEHLTKSLADVE---SQVSVQNQEKDALLGKLALLQEERDKLIVEMDKSLLENQslggsCESLKLALG 1555
Cdd:pfam15921  566 ILRQQIENMTQLVGQHGRTAGAMQvekAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE-----LEKVKLVNA 640

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1556 GltEDKEKLMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHvvesvrqekqEVYAKLRSAESDK 1635
Cdd:pfam15921  641 G--SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN----------KLKMQLKSAQSEL 708

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1636 REREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGANESMEALLSSNASLKEELERITLEYKTL 1715
Cdd:pfam15921  709 EQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 564376925  1716 SKEFEALMAEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKDV 1762
Cdd:pfam15921  789 AGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESV 835
PTZ00121 PTZ00121
MAEBL; Provisional
 1717-2505 2.14e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 2.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1717 KEFEALMAEKNTLSEETRN-LKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAV-VGKSQEQDSLSENAKLEDAEATLL 1794
Cdd:PTZ00121 1077 KDFDFDAKEDNRADEATEEaFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEeARKAEDARKAEEARKAEDAKRVEI 1156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1795 ANSAKPGVSETFSSHDDinnylqqlDQLKGRIAELEMEKQKDRELSQTLENEKNAlltqiSAKDSELKLLEEEVAKINml 1874
Cdd:PTZ00121 1157 ARKAEDARKAEEARKAE--------DAKKAEAARKAEEVRKAEELRKAEDARKAE-----AARKAEEERKAEEARKAE-- 1221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1875 NQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEmqNLKRCVSELEEEKQQLVK 1954
Cdd:PTZ00121 1222 DAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKAD--ELKKAEEKKKADEAKKAE 1299

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1955 EKTKVEsEIRKEYMEKIQGAQ---KGPGSKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQK 2031
Cdd:PTZ00121 1300 EKKKAD-EAKKKAEEAKKADEakkKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2032 DLDATKGNlAQAVEHHKKAQAELSSFKILLDDTQ-SEAARVLADNLKLKKELQSNKESIKSQIKQKdedllRRLEQAEEK 2110
Cdd:PTZ00121 1379 KADAAKKK-AEEKKKADEAKKKAEEDKKKADELKkAAAAKKKADEAKKKAEEKKKADEAKKKAEEA-----KKADEAKKK 1452

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2111 HRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWEQ 2190
Cdd:PTZ00121 1453 AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEE 1532

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2191 RFGDAIQTKEEEVRLKEENCTALKDQLRQMTIHMEELKitvsRLEHDKEIWESKAQTELQHQQKAYD---KLQEENKELM 2267
Cdd:PTZ00121 1533 AKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK----KAEEDKNMALRKAEEAKKAEEARIEevmKLYEEEKKMK 1608

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2268 SQLEEAGQLYHDSKNELTKLESELK---SLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNCKFNCEQLETDLTASR 2344
Cdd:PTZ00121 1609 AEEAKKAEEAKIKAEELKKAEEEKKkveQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEK 1688

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2345 ELTTRLHDEinvKEQKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALET 2424
Cdd:PTZ00121 1689 KAAEALKKE---AEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKE 1765

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2425 IKKESLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEER-HLSVILE---------------KDELIQDAAAENNKLKEE 2488
Cdd:PTZ00121 1766 EEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFdNFANIIEggkegnlvindskemEDSAIKEVADSKNMQLEE 1845

                         810
                  ....*....|....*..
gi 564376925 2489 IRGLRGHMDDLNSENAK 2505
Cdd:PTZ00121 1846 ADAFEKHKFNKNNENGE 1862
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2319-3068 1.90e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.90e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2319 IKQQEADIQNCKFNCEQLETDLTASRELTTRLHDEINVKEqKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLS--- 2395
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREYEGYELLKEKEALERQKEAIERQLAsle 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2396 -QEEEENLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEErhlsvilEKDEL 2474
Cdd:TIGR02169  251 eELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE-------DAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2475 IQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVitikdsqqRQLLEAQLQQNKELRNECVKLEGRLK 2554
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDL--------RAELEEVDKEFAETRDELKDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2555 GSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHE-----EGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQ 2629
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAkinelEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2630 EELVCVQKEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAEER--VAELARDLVEMEQKLLTvtkenkdltAQIQAFG 2707
Cdd:TIGR02169  476 EEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIqgVHGTVAQLGSVGERYAT---------AIEVAAG 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2708 KSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGRQDLGRESDVLSQAAF------------------------PLTT 2763
Cdd:TIGR02169  547 NRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVigfavdlvefdpkyepafkyvfgdTLVV 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2764 SENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSFTKAMTSLQNERDHLWNELEKFRKSEEGKQrsaaPSAASSPA 2843
Cdd:TIGR02169  627 EDIEAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ----SELRRIEN 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2844 EVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMNQEITELRplkAQLQESQDQTKALQMMKEELRQENLSWQHELHQLRV 2923
Cdd:TIGR02169  703 RLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE---EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2924 EKNSWELHERRMKEQYLMAISDK-DQQLGHLQNLLRELRSSSQTQILPTQYQRQASsgtsaaldgsQNLVYETDCLRTQL 3002
Cdd:TIGR02169  780 ALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI----------QELQEQRIDLKEQI 849

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564376925  3003 NDSLKEIHQKELRIQQLNSKFSQLLEEKNILSTQLRDANQSLRDSQHHYSNLFNHCAILERQVQQL 3068
Cdd:TIGR02169  850 KSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1927-2700 1.50e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.21  E-value: 1.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1927 KNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEY-MEKIQGAQKGPGSKIHAKELQELLKEKQQEVKQLQKDC 2005
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQlKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2006 IRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSN 2085
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2086 KESIKSQIKQKDEDLLRRLEQAEEKhrkekknmqEKLDALHREKAHVEDTLAEIQvsltRKDKDMKELQQSLDSTLAQLA 2165
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEE---------EELEKLQEKLEQLEEELLAKK----KLESERLSSAAKLKEEELELK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2166 AFTKSMSSLQDDRDRVIDEAKKWEQRFGDAIQTKEEEVRLKEENCTALKDQLRQMTIHMEELKITVSRLEHDKEIWESKA 2245
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2246 QTELQHQQKAYDKLQEE--NKELMSQLEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQE 2323
Cdd:pfam02463  481 KLQEQLELLLSRQKLEErsQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2324 ADIQNCKFNCEQLETDLTASRELTTRLHDE---INVKEQKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLSQEEEE 2400
Cdd:pfam02463  561 EERQKLVRALTELPLGARKLRLLIPKLKLPlksIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKES 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2401 NLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDdrdrivsdyrQLEERHLSVILEKDELIQDAAA 2480
Cdd:pfam02463  641 AKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESE----------LAKEEILRRQLEIKKKEQREKE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2481 ENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLN----EVITIKDSQQRQLLEAQLQQNKELRNECVKLEGRLKGS 2556
Cdd:pfam02463  711 ELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEeeeeEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEE 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2557 EAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHEEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQ 2636
Cdd:pfam02463  791 EKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ 870

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564376925  2637 KEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAEER-VAELARDLVEMEQKLLTVTKENKDLT 2700
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKlNLLEEKENEIEERIKEEAEILLKYEE 935
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1561-2033 8.62e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 8.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1561 KEKLMKELESVRcSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQ--EVYAKLRSAESDKRER 1638
Cdd:COG4717    66 PELNLKELKELE-EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAEL 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1639 EKQLQDAeqemeemkekmrkfaKSKQQKILELEEENDRLRAEAQPVggANESMEALLSSNASLKEELERITLEYKTLSKE 1718
Cdd:COG4717   145 PERLEEL---------------EERLEELRELEEELEELEAELAEL--QEELEELLEQLSLATEEELQDLAEELEELQQR 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1719 FEALMAEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTeAVVGKSQEQDSLSENAKLEDAEATLLANSA 1798
Cdd:COG4717   208 LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAA-ALLALLGLGGSLLSLILTIAGVLFLVLGLL 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1799 KPGVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQI 1878
Cdd:COG4717   287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1879 QEELSRVTKLKETAEEEKDDLEERLM---------NQLAELNGSIGNYYQDVTD--AQIKNEQLESEMQNLKRCVSELEE 1947
Cdd:COG4717   367 ELEQEIAALLAEAGVEDEEELRAALEqaeeyqelkEELEELEEQLEELLGELEEllEALDEEELEEELEELEEELEELEE 446

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1948 EKQQLVKEKTKVESEIrkEYMEKiqgaqkgpgskihAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHT 2027
Cdd:COG4717   447 ELEELREELAELEAEL--EQLEE-------------DGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYRE 511


                  ....*.
gi 564376925 2028 ESQKDL 2033
Cdd:COG4717   512 ERLPPV 517
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2505-2797 8.68e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 8.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2505 KLDAELIQYRRDLNEvitikdsQQRQLLEAQLQQNKELRNEcvkLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSF 2584
Cdd:COG1196   224 ELEAELLLLKLRELE-------AELEELEAELEELEAELEE---LEAELAELEAELEELRLELEELELELEEAQAEEYEL 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2585 KEQLTALheEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELvcvqKEASKKVSEIEDKLKRELKHLHHNAgim 2664
Cdd:COG1196   294 LAELARL--EQDIARLEERRRELEERLEELEEELAELEEELEELEEEL----EELEEELEEAEEELEEAEAELAEAE--- 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2665 rNETETAEERVAELARDLVEMEQKLLTVTKENKDLTAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGR 2744
Cdd:COG1196   365 -EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 564376925 2745 QDLGRESDVLSQAAfpLTTSENISSRLEKLNQQLTSKDEQLLHLSSELESSHN 2797
Cdd:COG1196   444 LEEAAEEEAELEEE--EEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1587-2154 2.35e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 2.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1587 KELQKEYEVLLQSYENvsneaerIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKqqk 1666
Cdd:PRK03918  175 KRRIERLEKFIKRTEN-------IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELE--- 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1667 iLELEEENDRLRAEAQPVGGANESMEALLSSNASLKEELERITlEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQELK 1746
Cdd:PRK03918  245 -KELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1747 QASLETT-EKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKPGVSETFSSHDDINNylqQLDQLKGR 1825
Cdd:PRK03918  323 INGIEERiKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEK---ELEELEKA 399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1826 IAELEMEKQKDRELSQTLENEKNALLTQISA-KDSELK------LLEEEVAKinMLNQQIQEELSRVTKLKETAEEEKDD 1898
Cdd:PRK03918  400 KEEIEEEISKITARIGELKKEIKELKKAIEElKKAKGKcpvcgrELTEEHRK--ELLEEYTAELKRIEKELKEIEEKERK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1899 LEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRcVSELEEEKQQLVKEKTKVESEIR--KEYMEKIQGAQK 1976
Cdd:PRK03918  478 LRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEE-LEKKAEEYEKLKEKLIKLKGEIKslKKELEKLEELKK 556

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1977 gpgskiHAKELQELLKEKQQEVKQLQKDcIRYLG--RISALEKTVKALEFVHTESQKDLDATKgnlaqavehhkkaqaEL 2054
Cdd:PRK03918  557 ------KLAELEKKLDELEEELAELLKE-LEELGfeSVEELEERLKELEPFYNEYLELKDAEK---------------EL 614

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2055 SSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVED 2134
Cdd:PRK03918  615 EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKK 694

                         570       580
                  ....*....|....*....|
gi 564376925 2135 TLAEIQVSLTRKDKDMKELQ 2154
Cdd:PRK03918  695 TLEKLKEELEEREKAKKELE 714
PRK11281 PRK11281
mechanosensitive channel MscK;
161-435 5.49e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 49.14  E-value: 5.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  161 LQAQLDQAQS-EQASQLDK-SSAEMEDFVLMRQKLQEKEELIGALQTQLSQTQAEQA---AQLSSMQqvvreKDARFETQ 235
Cdd:PRK11281   41 VQAQLDALNKqKLLEAEDKlVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRqaqAELEALK-----DDNDEETR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  236 VRLHEDELLQLVTQSdveTEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQR----NQDLSQQLQLLEAEHST 311
Cdd:PRK11281  116 ETLSTLSLRQLESRL---AQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRlqqiRNLLKGGKVGGKALRPS 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  312 LRNTMEAERQ--ESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQygTLQqrheTEMEEKTACISllQKNEQE 389
Cdd:PRK11281  193 QRVLLQAEQAllNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQ--LLQ----EAINSKRLTLS--EKTVQE 264

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 564376925  390 LQSACDALKEENSKLLQEQQEQAAKSAQAL-QQLE--DELQQKSKEISQ 435
Cdd:PRK11281  265 AQSQDEAARIQANPLVAQELEINLQLSQRLlKATEklNTLTQQNLRVKN 313
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 153-425 7.64e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 48.68  E-value: 7.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  153 EKEKLISNLQAQLDQAQSEQASQLDKSSAEMEdfvlmRQKL-QEKEELIGALQTqlSQTQAEQAAQLSSMQQVVREKDAr 231
Cdd:NF012221 1539 ESSQQADAVSKHAKQDDAAQNALADKERAEAD-----RQRLeQEKQQQLAAISG--SQSQLESTDQNALETNGQAQRDA- 1610

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  232 FETQVRLHEDELLQLVTQSDV-ETEVQQKLRVMQRKLEEHEEALLGRAQvVDLLQKELTSAEQRNQdlsqqlqlleaehs 310
Cdd:NF012221 1611 ILEESRAVTKELTTLAQGLDAlDSQATYAGESGDQWRNPFAGGLLDRVQ-EQLDDAKKISGKQLAD-------------- 1675

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  311 tLRNTMEAERQESKILMEKVELEMAERkeelYQLQGQLERAG-QAQAELEMQYG-TLQQRHETEMEEKTACISLlqkneQ 388
Cdd:NF012221 1676 -AKQRHVDNQQKVKDAVAKSEAGVAQG----EQNQANAEQDIdDAKADAEKRKDdALAKQNEAQQAESDANAAA-----N 1745

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 564376925  389 ELQSAcdalKEENSKLLQEQQEQAAKSAQALQQLEDE 425
Cdd:NF012221 1746 DAQSR----GEQDASAAENKANQAQADAKGAKQDESD 1778
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1441-2159 8.44e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.48  E-value: 8.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1441 ELKKQPKELEEESKAKQQLQRKLQAALISRKEALK-----------ENKSLQEQLSSARDAVEHLTKSLADVESQVSVQN 1509
Cdd:TIGR04523   37 QLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINnsnnkikileqQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDK 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1510 QEKDALLGKLALLQEERDKLIVEMDKSLLEnqslggsCESLKLALGGLTEDKEKLMKELESVRCSKIAESTEWQEKHKEL 1589
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTE-------IKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1590 QKeyevllqsyenvSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILE 1669
Cdd:TIGR04523  190 DK------------IKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQ 257

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1670 LEEENDRLraeaqpvgganesmeallssnaslKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQELKQAS 1749
Cdd:TIGR04523  258 LKDEQNKI------------------------KKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELK 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1750 LETTEKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKledaeatllansakpgvsETFSSHDDINNYLQQLDQLKGRIAEL 1829
Cdd:TIGR04523  314 SELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKK------------------ELTNSESENSEKQRELEEKQNEIEKL 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1830 EMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEerlmNQLAE 1909
Cdd:TIGR04523  376 KKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLT----NQDSV 451

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1910 LNGSIGNYyqdvtdaQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKgpgskihAKELQE 1989
Cdd:TIGR04523  452 KELIIKNL-------DNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEK-------VKDLTK 517

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1990 LLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFvhtesqkdlDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAA 2069
Cdd:TIGR04523  518 KISSLKEKIEKLESEKKEKESKISDLEDELNKDDF---------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ 588

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2070 rvladnlKLKKELQSNKESIKSQIKQKD---EDLLRRLEQAEEKHRK---EKKNMQEKLDALHREKAHVEDTLAEIQVSL 2143
Cdd:TIGR04523  589 -------ELIDQKEKEKKDLIKEIEEKEkkiSSLEKELEKAKKENEKlssIIKNIKSKKNKLKQEVKQIKETIKEIRNKW 661

                          730
                   ....*....|....*.
gi 564376925  2144 TRKDKDMKELQQSLDS 2159
Cdd:TIGR04523  662 PEIIKKIKESKTKIDD 677
mukB PRK04863
chromosome partition protein MukB;
2565-2976 5.66e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.10  E-value: 5.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2565 MSLDALQEeNQGLSKEIKSFKEQLTAlHEEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKV- 2643
Cdd:PRK04863  244 MTLEAIRV-TQSDRDLFKHLITESTN-YVAADYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNe 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2644 --SEIEDKLKRELKHLH--HNAGIMRNETETAEERVAELARDLVEMEQklltVTKENKDLTAQIQAfgkSMSSLQDSRDH 2719
Cdd:PRK04863  322 aeSDLEQDYQAASDHLNlvQTALRQQEKIERYQADLEELEERLEEQNE----VVEEADEQQEENEA---RAEAAEEEVDE 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2720 ATEELSDLKKKYDASLKELAQLKGRQDLGRESDVLSQAafPLTTSENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQV 2799
Cdd:PRK04863  395 LKSQLADYQQALDVQQTRAIQYQQAVQALERAKQLCGL--PDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAH 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2800 QSFTKAMTSLQN-----ERDHLWNE-LEKFRKSEEgkQRSAAPSAASSPAEVQSLKKAMsSLQNDRDRLLKElknLQQQY 2873
Cdd:PRK04863  473 SQFEQAYQLVRKiagevSRSEAWDVaRELLRRLRE--QRHLAEQLQQLRMRLSELEQRL-RQQQRAERLLAE---FCKRL 546

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2874 LQMNQEITELRPLKAQLQESQDQtkaLQMMKEELRQENLSWQHELHQLRVEKNS-------W-ELHER--RMKEQYLMAI 2943
Cdd:PRK04863  547 GKNLDDEDELEQLQEELEARLES---LSESVSEARERRMALRQQLEQLQARIQRlaarapaWlAAQDAlaRLREQSGEEF 623

                         410       420       430
                  ....*....|....*....|....*....|...
gi 564376925 2944 SDKDQQLGHLQNLLRELRSSSQTQILPTQYQRQ 2976
Cdd:PRK04863  624 EDSQDVTEYMQQLLERERELTVERDELAARKQA 656
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 73-359 6.17e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.50  E-value: 6.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925    73 QLQQKDEALQEEKKGAESKikkiklhAKAKITSLNKQIEELKTQGGAASppEVQAEELSKHDKSSTEEEMEVEKIKHELQ 152
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKE-------EKAREVERRRKLEEAEKARQAEM--DRQAAIYAEQERMAMERERELERIRQEER 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   153 EKEKLISNLQA---------QLDQAQSEQASQLDKSSAEMEdfVLMRQKLQEKEE--LIGALQTQLSQTQAEQAAQLSSM 221
Cdd:pfam17380  359 KRELERIRQEEiameisrmrELERLQMERQQKNERVRQELE--AARKVKILEEERqrKIQQQKVEMEQIRAEQEEARQRE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   222 QQVVREKDARFETQVRLHEDEllqlvTQSDVETEVQQKLRVMQRKLE---EHEEALLGRAQVVDLLQKELTSAEQRNQDL 298
Cdd:pfam17380  437 VRRLEEERAREMERVRLEEQE-----RQQQVERLRQQEEERKRKKLElekEKRDRKRAEEQRRKILEKELEERKQAMIEE 511

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925   299 SQQLQLLEAEHSTLRNTMEAERQESKILME-KVELEMAERKeelyQLQGQLERAGQAQAELE 359
Cdd:pfam17380  512 ERKRKLLEKEMEERQKAIYEEERRREAEEErRKQQEMEERR----RIQEQMRKATEERSRLE 569
PRK12704 PRK12704
phosphodiesterase; Provisional
 63-181 3.76e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 3.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   63 LKDIISKQDAQLQQK-DEALQEEKKGAESKIKKIKLHAKAKITSLNKQIE-ELKTQGGAASPPE---VQAEE-LSKHDKS 136
Cdd:PRK12704   25 RKKIAEAKIKEAEEEaKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEkELRERRNELQKLEkrlLQKEEnLDRKLEL 104

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 564376925  137 STEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSA 181
Cdd:PRK12704  105 LEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISG 149
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1407-2165 6.65e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.41  E-value: 6.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1407 MEEQERLIKALHTQLEMQAKEHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAaliSRKEALKENKSLQEQLSS 1486
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQ---SQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1487 ARDAVEHLtksLADVESQVsvqNQEKDALLGKLALLQEERDKLI---VEMDKSLLENQSLggSCESLKLALGGLTEDKEK 1563
Cdd:pfam15921  157 AKCLKEDM---LEDSNTQI---EQLRKMMLSHEGVLQEIRSILVdfeEASGKKIYEHDSM--STMHFRSLGSAISKILRE 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1564 LMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYEnvsneaERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQ 1643
Cdd:pfam15921  229 LDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLE 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1644 DAEQEMEEMKEKMrkfakskQQKILELEEENDRLRAEaqpvgganesmeaLLSSNASLKEELERITLEYKTLSKEFEALM 1723
Cdd:pfam15921  303 IIQEQARNQNSMY-------MRQLSDLESTVSQLRSE-------------LREAKRMYEDKIEELEKQLVLANSELTEAR 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1724 AEKNTLSEETRNL--KLQVEAQELKQASLETTEKSDEPKDVIEEVTeavvGKSQEQDSLSENAKLEDAEATLLANSAKPG 1801
Cdd:pfam15921  363 TERDQFSQESGNLddQLQKLLADLHKREKELSLEKEQNKRLWDRDT----GNSITIDHLRRELDDRNMEVQRLEALLKAM 438

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1802 VSETFSSHDD----INNYLQQLDQLKGRIAELEMEKQKDRELSQ-------TLENEKNALLTQISAKDSELKLLEEEVAK 1870
Cdd:pfam15921  439 KSECQGQMERqmaaIQGKNESLEKVSSLTAQLESTKEMLRKVVEeltakkmTLESSERTVSDLTASLQEKERAIEATNAE 518

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1871 INMLNQQIQEELSRVTKLKETAEE----------------EKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESE 1934
Cdd:pfam15921  519 ITKLRSRVDLKLQELQHLKNEGDHlrnvqtecealklqmaEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKE 598

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1935 MQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGpgskihaKELQELLKEKQQEVKQLQKDCIRYLGRISA 2014
Cdd:pfam15921  599 INDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAG-------SERLRAVKDIKQERDQLLNEVKTSRNELNS 671

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2015 LEKTVKALEFVHTESQKDLDATKGNLAQAVehhKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSqIK 2094
Cdd:pfam15921  672 LSEDYEVLKRNFRNKSEEMETTTNKLKMQL---KSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDA-LQ 747

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564376925  2095 QKDEDLLRRLEQA-EEKH--RKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLA 2165
Cdd:pfam15921  748 SKIQFLEEAMTNAnKEKHflKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFA 821
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 720-1623 1.88e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.13  E-value: 1.88e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   720 FKESAEEARSTLtavcEERDQLLYRVKelDVLGELRAQVRELETSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaks 799
Cdd:TIGR02168  170 YKERRKETERKL----ERTRENLDRLE--DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------ 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   800 kDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKK 879
Cdd:TIGR02168  238 -REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   880 DVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDsgaesspkhgphessa 959
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELA----EELAELEEKLEELKEELESLEAELEELEAELEELESRLEE---------------- 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   960 qepvckdaLQQELEWLRKESEQRKRKLQAALISRKELLQKVSKLEEELAKVREEstkdslRESEKRELEEDSKNKddpek 1039
Cdd:TIGR02168  377 --------LEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQE------IEELLKKLEEAELKE----- 437

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1040 ygtsewrelevsLRLTISEKEVELEGIRRDLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEEITENQATIQKFitgt 1119
Cdd:TIGR02168  438 ------------LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL---- 501

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1120 MDAGDGDSAVKEtsvsspPRAGGGEHWKPELEGKIVDLEKEK---TQLQKKLQEALISRKAILKKAQEkekHLKeelkeq 1196
Cdd:TIGR02168  502 EGFSEGVKALLK------NQSGLSGILGVLSELISVDEGYEAaieAALGGRLQAVVVENLNAAKKAIA---FLK------ 566

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1197 kdayrhlqeqfdgqskenENIAARLRQLQAKESTDQQLPGTGQQEPTHGSEGLSLegtepasESDLHAAQPSHPGETATL 1276
Cdd:TIGR02168  567 ------------------QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGV-------AKDLVKFDPKLRKALSYL 621

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1277 QATVSVAQIQDQLKEIEVEKEELELKIS-----------------STTSELTKKSEEVLLLQEQINEQGLEIQNLKAASH 1339
Cdd:TIGR02168  622 LGGVLVVDDLDNALELAKKLRPGYRIVTldgdlvrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALA 701

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1340 EAKAHTEQLKQELESSQLKIADLEH-LKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALH 1418
Cdd:TIGR02168  702 ELRKELEELEEELEQLRKELEELSRqISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE 781

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1419 T---QLEMQAKEHEERLKQVQVEICELKKQPKELEEE----SKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAV 1491
Cdd:TIGR02168  782 AeieELEAQIEQLKEELKALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEI 861

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1492 EHLTKSLADVESQVSVQNQEKDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESV 1571
Cdd:TIGR02168  862 EELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|..
gi 564376925  1572 RcSKIAEstewqekhkELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQE 1623
Cdd:TIGR02168  942 Q-ERLSE---------EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1876-2632 2.04e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.04e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1876 QQIQEELSRVTKLKETAEEEKDDLEERLMN---QLAELNGSIGNYYQDVTDAQikneqleSEMQNLKRCVSELEEEKQQL 1952
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQEleeKLEELRLEVSELEEEIEELQ-------KELYALANEISRLEQQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1953 VKEKTKVESEIrKEYMEKIQGAQKgpgskiHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKD 2032
Cdd:TIGR02168  308 RERLANLERQL-EELEAQLEELES------KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2033 LDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHR 2112
Cdd:TIGR02168  381 LETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELE 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2113 KEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWEQRF 2192
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGL 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2193 GDAIQTKEEEVRLKEENCTALKDQLRQmtiHMEelKITVSRLEHDKEIWESKAQTELQH------QQKAYDKLQEENKEL 2266
Cdd:TIGR02168  519 SGILGVLSELISVDEGYEAAIEAALGG---RLQ--AVVVENLNAAKKAIAFLKQNELGRvtflplDSIKGTEIQGNDREI 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2267 MSQLEEAGQLYHDSKNELTKLESELKSLKDQS---TDLKNSLEK------------------------------------ 2307
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELakklrpgyrivtldgdlvrpggvitggsaktnssil 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2308 CREHE-NNLEGIIKQQEADIQNCKFNCEQLETDLTASRELTTRLHDEINVKEQKIISLLS--GKEEAIQVAIAELHQQHS 2384
Cdd:TIGR02168  674 ERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKdlARLEAEVEQLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2385 KEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERh 2464
Cdd:TIGR02168  754 KELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR- 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2465 lsvilekdelIQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVITIKDSQQRQLLEAQLQQnKELRN 2544
Cdd:TIGR02168  833 ----------IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL-EELSE 901

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2545 ECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALheegalavYHAQLRVREEEVQKLTAALSSSQKR 2624
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE--------YSLTLEEAEALENKIEDDEEEARRR 973


                   ....*...
gi 564376925  2625 TVDLQEEL 2632
Cdd:TIGR02168  974 LKRLENKI 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 189-947 5.16e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.04  E-value: 5.16e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   189 MRQKLQEKEELIGALQTQLS--QTQAEQAaqlssmQQVVREKDARFETQVRLHEDELLQLVTQSDvetEVQQKLRVMQRK 266
Cdd:TIGR02168  184 TRENLDRLEDILNELERQLKslERQAEKA------ERYKELKAELRELELALLVLRLEELREELE---ELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   267 LEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQLQlleaEHSTLRNTMEAERQESKILMEKVELEMAERKEELYQLQG 346
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQKELY----ALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   347 QLERAGQAQAELEMQYGTLQQRHETEMEEKTACISLLQKNEQELQSACDALKEENSKLLQEQQEQAAKSAQaLQQLEDEL 426
Cdd:TIGR02168  331 KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE-IERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   427 QQKSKEISQFV-NKPNLEKHETSSQTSLPDVYNEGVQAVMEESVASLQKRVLELENEKGALLLSSLELEELRAENEKLCS 505
Cdd:TIGR02168  410 ERLEDRRERLQqEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   506 RITLLEA--QNRAGEADGmvcevstAGIALLNRSDS-----------STEESGQDVLENTFSqkhKELSVLLVEMKEAQ- 571
Cdd:TIGR02168  490 RLDSLERlqENLEGFSEG-------VKALLKNQSGLsgilgvlseliSVDEGYEAAIEAALG---GRLQAVVVENLNAAk 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   572 EEIAFLKSQLQGKR------PEGDYEVLDRKEVQMMESEGLPSVTARDVLCAPRDKNSVPA-------VEGEQAGMRDQH 638
Cdd:TIGR02168  560 KAIAFLKQNELGRVtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYllggvlvVDDLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   639 GTLEAGPLNDTGMELNSPQPDGVDKSLSAPHVCLCHQGELERLKTQVLELETSLHTAkethEKNLSEKAKEISSLTQLTK 718
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   719 EFKESAEEARSTLTAVCEErdqllyrvkeldvLGELRAQVRELETSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAK 798
Cdd:TIGR02168  716 QLRKELEELSRQISALRKD-------------LARLEAEVEQLEERIAQLSKEL----TELEAEIEELEERLEEAEEELA 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   799 SKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKK 878
Cdd:TIGR02168  779 EAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA 858

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925   879 KDVETLQQTIQEKDQQVTELSF---SMTEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAE 947
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELR 930
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1429-2310 8.21e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 8.21e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1429 EERLKQVQVEICELKKQPKELEEESKAKQQLqRKLQAAL--ISRKEALKENKSLQEQLSSARDAVEHLTKSLADVESQVs 1506
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKSLERQAEKAERY-KELKAELreLELALLVLRLEELREELEELQEELKEAEEELEELTAEL- 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1507 vqnQEKDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESVRCSKIAESTEWQEKH 1586
Cdd:TIGR02168  263 ---QELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1587 KELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQK 1666
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1667 ILELEEENDRL-RAEAQPVGGANESMEALLssnASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQEL 1745
Cdd:TIGR02168  420 QQEIEELLKKLeEAELKELQAELEELEEEL---EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1746 KQASLETteKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKPGVSETFSSHDDINNYLQQLDqlKGR 1825
Cdd:TIGR02168  497 LQENLEG--FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNE--LGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1826 IAELEMEKQKDRELsqtlENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKD-DLEERLM 1904
Cdd:TIGR02168  573 VTFLPLDSIKGTEI----QGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKlRPGYRIV 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1905 NQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEktkveseirkeymekiqgaqkgpgskihA 1984
Cdd:TIGR02168  649 TLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKA----------------------------L 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1985 KELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLDDT 2064
Cdd:TIGR02168  701 AELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2065 QSEAARVLADNLKLKKELQSNKESIKSQIKQKDE--DLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEDTLAEIQVS 2142
Cdd:TIGR02168  781 EAEIEELEAQIEQLKEELKALREALDELRAELTLlnEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAE 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2143 LTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWEQRFGDAiqtkeeevrlkEENCTALKDQLRQMTI 2222
Cdd:TIGR02168  861 IEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL-----------RRELEELREKLAQLEL 929

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2223 HMEELKITVSRLehdKEIWESKAQTELQHQQKAY-------DKLQEENKELMSQLEEAGQLYHDSKNELTKLESELKSLK 2295
Cdd:TIGR02168  930 RLEGLEVRIDNL---QERLSEEYSLTLEEAEALEnkieddeEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLT 1006

                          890
                   ....*....|....*
gi 564376925  2296 DQSTDLKNSLEKCRE 2310
Cdd:TIGR02168 1007 AQKEDLTEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2096-2912 1.33e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.50  E-value: 1.33e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2096 KDEDLLRRLEQAE--EKHRKEKKNMQEKLDALHREKAHVEDTLAEIQVSL------TRKDKDMKELQQSLDStlAQLAAF 2167
Cdd:TIGR02168  153 KPEERRAIFEEAAgiSKYKERRKETERKLERTRENLDRLEDILNELERQLkslerqAEKAERYKELKAELRE--LELALL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2168 TKSMSSLQDDRDRVIDEAKKWEQRFGDA---IQTKEEEVRLKEENCTALKDQLRQMTIHMEELKITVSRLEHDKeiwesk 2244
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELtaeLQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQK------ 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2245 aqtelQHQQKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEA 2324
Cdd:TIGR02168  305 -----QILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2325 DIqnckfncEQLETDLTASRELTTRLHDEINVKEQKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLSQEEEENLTL 2404
Cdd:TIGR02168  380 QL-------ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEEL 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2405 EEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDRIvsdyrqleerhlsvilekdELIQDAAAENNK 2484
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL-------------------EGFSEGVKALLK 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2485 LKEEIRGLRGHMDDLNSENAKLDAEL-IQYRRDLNEVITIKDSQQRQLLEAQLQQNKELRNECVklEGRLKGseAEKQSL 2563
Cdd:TIGR02168  514 NQSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLP--LDSIKG--TEIQGN 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2564 QMSLDALQEENQGLSKEIKSFKEQLTALHE------------EGALAVYH------------------------------ 2601
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddlDNALELAKklrpgyrivtldgdlvrpggvitggsaktn 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2602 -------AQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKVSEIEDKlKRELKHLHHNAGIMRNETETAEER 2674
Cdd:TIGR02168  670 ssilerrREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL-SRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2675 VAELARDLVEMEQKLLTVTKENKDLTAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGR--QDLGRESD 2752
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEaaNLRERLES 828

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2753 VLSQAAFPLTTSENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSFTKAMTSLQNERDHLWNELEKFR---KSEEG 2829
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSeelRELES 908

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2830 KQRSAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMNQEITELRPlkAQLQESQDQTKALQMMKEELRQ 2909
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIE--DDEEEARRRLKRLENKIKELGP 986


                   ...
gi 564376925  2910 ENL 2912
Cdd:TIGR02168  987 VNL 989
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 801-1638 1.12e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 87.82  E-value: 1.12e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   801 DVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEvLEGAERMKDISKEMEELSQALSQKELE-----IAQMDQLLL 875
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLKEKEalerqKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   876 EKKKDVETLQQTIQEKDQQVTELSFSMTEKMVQLN----EEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAEsspk 951
Cdd:TIGR02169  248 SLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKdlgeEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEER---- 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   952 hgphesSAQEPVCKDALQQELEWLRKESEQ---RKRKLQAALISRKE----LLQKVSKLEEELAKVREEStkdslreSEK 1024
Cdd:TIGR02169  324 ------LAKLEAEIDKLLAEIEELEREIEEerkRRDKLTEEYAELKEeledLRAELEEVDKEFAETRDEL-------KDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1025 RELEEDSKNKDDPEKYGTSEWRELEVSLRLTISEKEVELEGIRRDLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEE 1104
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1105 ITENQATIQKFITGTMDAGDGDSAVKETSVSSPPRAGGGEHWKPELE-------GKIVDLEKEKTQLQKKLQEALISR-K 1176
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKasiqgvhGTVAQLGSVGERYATAIEVAAGNRlN 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1177 AILKKAQEKEKHLKEELKEQKdayrhlqeqfdgqskeneniAARLRQLQAKESTDQQLPGTGQQEPTHGSEGLSLEGTEP 1256
Cdd:TIGR02169  551 NVVVEDDAVAKEAIELLKRRK--------------------AGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDP 610

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1257 ASES-------------DLHAAQPshpgetatLQATVSVAQIQDQLKEIEVEKEELELKISSTTSELTKKSEEVLLLQEQ 1323
Cdd:TIGR02169  611 KYEPafkyvfgdtlvveDIEAARR--------LMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRER 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1324 INEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIADLE-HLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTT 1402
Cdd:TIGR02169  683 LEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEkEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1403 VQTEMEEQERLIKALHTQLE-MQAKEHEERLKQVQVEICELKKQPKELE----EESKAKQQLQRKLQAALISRKEALKEN 1477
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEALNdLEARLSHSRIPEIQAELSKLEEEVSRIEarlrEIEQKLNRLTLEKEYLEKEIQELQEQR 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1478 KSLQEQLSSARDAVEHLTKSLADVESQVSVQNQEKDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGL 1557
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1558 TEDKEKLMKELESV-----RCSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAE 1632
Cdd:TIGR02169  923 KAKLEALEEELSEIedpkgEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEER 1002


                   ....*.
gi 564376925  1633 SDKRER 1638
Cdd:TIGR02169 1003 KAILER 1008
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2016-2893 3.02e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 3.02e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2016 EKTVKALEFVHTESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQ 2095
Cdd:TIGR02168  210 EKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2096 KDE--DLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSmss 2173
Cdd:TIGR02168  290 LYAlaNEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE--- 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2174 LQDDRDRVIDEAKKWEQRFGDAIQTKEEEvrlkeencTALKDQLRQMTIHMEELKITVSRLEHDKEIWESKAQ-TELQHQ 2252
Cdd:TIGR02168  367 LEELESRLEELEEQLETLRSKVAQLELQI--------ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEeAELKEL 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2253 QKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKqqeaDIQNCKFN 2332
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSE----GVKALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2333 CEQLETDLTasrelttRLHDEINVKEqkiisllsGKEEAIQVAIAELHQQ----HSKEIKELENLLSQEEEENLTLEEEN 2408
Cdd:TIGR02168  515 QSGLSGILG-------VLSELISVDE--------GYEAAIEAALGGRLQAvvveNLNAAKKAIAFLKQNELGRVTFLPLD 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2409 kraVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQ-------------DDRDRIVSDYRQLEERHLSVILEkDELI 2475
Cdd:TIGR02168  580 ---SIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRkalsyllggvlvvDDLDNALELAKKLRPGYRIVTLD-GDLV 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2476 --------QDAAAENNKL--KEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVitikdsqqrqlleaqLQQNKELRNE 2545
Cdd:TIGR02168  656 rpggvitgGSAKTNSSILerRREIEELEEKIEELEEKIAELEKALAELRKELEEL---------------EEELEQLRKE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2546 CVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHEEgalavyhaqlrvREEEVQKLTAALSSSQKrt 2625
Cdd:TIGR02168  721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER------------LEEAEEELAEAEAEIEE-- 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2626 vdlQEELVCVQKEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAEERVAELARDLVEMEQKLltvtkenKDLTAQIQA 2705
Cdd:TIGR02168  787 ---LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI-------EELSEDIES 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2706 FGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGRQdlgresdvlsqaafplttsENISSRLEKLNQQLTSKDEQL 2785
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASLEEALALLRSEL-------------------EELSEELRELESKRSELRREL 917

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2786 LHLSSELESSHNQVQSftkamtsLQNERDHLwneLEKFRKSEEGKQRSAAPSAASSPAEVQSLKKAMSSLQNDRDRL--- 2862
Cdd:TIGR02168  918 EELREKLAQLELRLEG-------LEVRIDNL---QERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELgpv 987

                          890       900       910
                   ....*....|....*....|....*....|....*
gi 564376925  2863 ----LKELKNLQQQYLQMNQEITELRPLKAQLQES 2893
Cdd:TIGR02168  988 nlaaIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1729-2489 3.37e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.26  E-value: 3.37e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1729 LSEETRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAVVGKSQEQDSLSENaKLEDAEAtllansakpgvsetfss 1808
Cdd:TIGR02168  218 LKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEEL-RLEVSEL----------------- 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1809 HDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVA----KINMLNQQIQEELSR 1884
Cdd:TIGR02168  280 EEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAeleeKLEELKEELESLEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1885 VTKLK------ETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTK 1958
Cdd:TIGR02168  360 LEELEaeleelESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQ 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1959 VESEIRKEYMEKIQGAQKGPGSKihAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVH------TESQKD 2032
Cdd:TIGR02168  440 AELEELEEELEELQEELERLEEA--LEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSegvkalLKNQSG 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2033 LDATKGNLAQAVEHHKKAQAE----LSSFKILLDDTQSEAARVLADNLK-----------LKKELQSNKESIKSQIKQKD 2097
Cdd:TIGR02168  518 LSGILGVLSELISVDEGYEAAieaaLGGRLQAVVVENLNAAKKAIAFLKqnelgrvtflpLDSIKGTEIQGNDREILKNI 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2098 EDLLRRLEQAEEKHRKEKKNMQEKLDALhrekaHVEDTLAEIQVslTRKDKDMKELQQSLDSTL-----AQLAAFTKSMS 2172
Cdd:TIGR02168  598 EGFLGVAKDLVKFDPKLRKALSYLLGGV-----LVVDDLDNALE--LAKKLRPGYRIVTLDGDLvrpggVITGGSAKTNS 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2173 SLQdDRDRVIDEAKKWEQRFGDAIQTKEEEVRLKEENCTALKDQLRQMTIHMEELKITVSRLEHDKEIWESKAQTELQhq 2252
Cdd:TIGR02168  671 SIL-ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEE-- 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2253 qkAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNCKFN 2332
Cdd:TIGR02168  748 --RIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRER 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2333 CEQLETDLTASRELTTRLHDEINVKEQKIISlLSGKEEAIQVAIAELHqqhsKEIKELENLLSQEEEENLTLEEENKRAV 2412
Cdd:TIGR02168  826 LESLERRIAATERRLEDLEEQIEELSEDIES-LAAEIEELEELIEELE----SELEALLNERASLEEALALLRSELEELS 900

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2413 EKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRD----RIVSDYRQLEERHLSVILEKDELIQDAAAENNKLKEE 2488
Cdd:TIGR02168  901 EELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDnlqeRLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980


                   .
gi 564376925  2489 I 2489
Cdd:TIGR02168  981 I 981
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1312-2166 4.84e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.49  E-value: 4.84e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1312 KKSEEVLLLQEQINEqgLEIQNLKAASHEAKAHTEQLKQELESSQLKIADLE-HLKTLQPELETLQKHVGQKEEEVSYLV 1390
Cdd:TIGR02168  210 EKAERYKELKAELRE--LELALLVLRLEELREELEELQEELKEAEEELEELTaELQELEEKLEELRLEVSELEEEIEELQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1391 GQLGEKEQTLTTVQTEMEEQERLIKALHTQLEmqakeheerlkQVQVEICELKKQPKELEEEskaKQQLQRKLQaalisr 1470
Cdd:TIGR02168  288 KELYALANEISRLEQQKQILRERLANLERQLE-----------ELEAQLEELESKLDELAEE---LAELEEKLE------ 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1471 kEALKENKSLQEQLSSARDAVEHLTKSLADVESQVSVQNQEKDALLGKLALLQEErdklIVEMDKSLlenqslggscESL 1550
Cdd:TIGR02168  348 -ELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE----IERLEARL----------ERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1551 KLALGGLTEDKEKLMKELESVRCSKI-AESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLR 1629
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAELKELqAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1630 SAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQkiLELEEEndrLRAEAQPVGGanESMEALLSSNASlkeelerit 1709
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL--ISVDEG---YEAAIEAALG--GRLQAVVVENLN--------- 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1710 leykTLSKEFEALmaEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAvvgksqeqdslseNAKLEDA 1789
Cdd:TIGR02168  557 ----AAKKAIAFL--KQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKF-------------DPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1790 EATLLANSAkpgVSETFSSHDDINNYLQQldqlKGRIAELEMEKQKDRELSQTLENEKNAlltQISAKDSELKLLEEEVA 1869
Cdd:TIGR02168  618 LSYLLGGVL---VVDDLDNALELAKKLRP----GYRIVTLDGDLVRPGGVITGGSAKTNS---SILERRREIEELEEKIE 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1870 KINMLNQQIQEELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEK 1949
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1950 QQLVKEKTkveseirkeymekiqgaqkgpgskihakELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALefvhtes 2029
Cdd:TIGR02168  764 EELEERLE----------------------------EAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL------- 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2030 QKDLDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKE---LQSNKESIKSQIKQKdEDLLRRLEQ 2106
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEieeLEELIEELESELEAL-LNERASLEE 887

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2107 AEEKHRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAA 2166
Cdd:TIGR02168  888 ALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE 947
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 103-928 1.37e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.95  E-value: 1.37e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   103 ITSLNKQIEELKTQGgaasppeVQAEELskHDKSSTEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAE 182
Cdd:TIGR02168  195 LNELERQLKSLERQA-------EKAERY--KELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   183 MEDFVLMRQKLQEKEELIGALQTQLSQTQAEQAaqlssmqqvvrekdaRFETQVRLHEDELLQLVTQSDVETEVQQKLrv 262
Cdd:TIGR02168  266 EEKLEELRLEVSELEEEIEELQKELYALANEIS---------------RLEQQKQILRERLANLERQLEELEAQLEEL-- 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   263 mQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQLQLLEAEHSTLRNTMEAERQESKILMEKVELEMAER---KE 339
Cdd:TIGR02168  329 -ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIerlEA 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   340 ELYQLQGQLERAGQAQAELEmqygtlQQRHETEMEEKTACISLLQKNEQELQSACDALKEEnsklLQEQQEQAAKSAQAL 419
Cdd:TIGR02168  408 RLERLEDRRERLQQEIEELL------KKLEEAELKELQAELEELEEELEELQEELERLEEA----LEELREELEEAEQAL 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   420 QQLEDELQQKSKEIsqFVNKPNLEKHETssqtslpdvYNEGVQAVMEES--VASLQKRVLEL-----ENEKGALLLSSLE 492
Cdd:TIGR02168  478 DAAERELAQLQARL--DSLERLQENLEG---------FSEGVKALLKNQsgLSGILGVLSELisvdeGYEAAIEAALGGR 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   493 LEELRAENEKLCSRITLLEAQNRAGEAdgMVCEVSTAGIALLNRSDSSTEESGQDVLentfsqkhKELSVLLVEMKEAQE 572
Cdd:TIGR02168  547 LQAVVVENLNAAKKAIAFLKQNELGRV--TFLPLDSIKGTEIQGNDREILKNIEGFL--------GVAKDLVKFDPKLRK 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   573 EIAFLksqLQGKRPEGDYEVLDRKEVQMMESEGLpsVTARDVLCAPRdknsvpaveGEQAGMRDQ--HGTLEagplNDTG 650
Cdd:TIGR02168  617 ALSYL---LGGVLVVDDLDNALELAKKLRPGYRI--VTLDGDLVRPG---------GVITGGSAKtnSSILE----RRRE 678

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   651 MELNSPQPDGVDKSLSAPHVclchqgELERLKTQVLELETslhtakethekNLSEKAKEISSLTQLTKEFKESAEEARST 730
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEK------ALAELRKELEELEE-----------ELEQLRKELEELSRQISALRKDLARLEAE 741

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   731 LTAVCEERDQLLYRVKELDV-LGELRAQVRELETSLAEAEKQRG---LDYESQRAQHNLLTEQIHSLSIEAKSKDVKIET 806
Cdd:TIGR02168  742 VEQLEERIAQLSKELTELEAeIEELEERLEEAEEELAEAEAEIEeleAQIEQLKEELKALREALDELRAELTLLNEEAAN 821

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   807 LQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQ 886
Cdd:TIGR02168  822 LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE 901

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*
gi 564376925   887 TIQEKDQQVTELSFSM---TEKMVQLNEEKFSLGVEIKTLKEQLS 928
Cdd:TIGR02168  902 ELRELESKRSELRRELeelREKLAQLELRLEGLEVRIDNLQERLS 946
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1346-2153 2.40e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.18  E-value: 2.40e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1346 EQLKQELESSQLKIADLEHlktlqpELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALhtqlEMQA 1425
Cdd:TIGR02168  235 EELREELEELQEELKEAEE------ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL----EQQK 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1426 KEHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALisrKEALKENKSLQEQLSSARDAVEHLTKSLADVESQV 1505
Cdd:TIGR02168  305 QILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKL---EELKEELESLEAELEELEAELEELESRLEELEEQL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1506 SVQNQEKDALLGKLALLQEErdklIVEMDKSLlenqslggscESLKLALGGLTEDKEKLMKELESVRCSKI-AESTEWQE 1584
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNE----IERLEARL----------ERLEDRRERLQQEIEELLKKLEEAELKELqAELEELEE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1585 KHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQ 1664
Cdd:TIGR02168  448 ELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSE 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1665 QkiLELEEEndrLRAEAQPVGGanESMEALLSSN--------ASLKE-ELERITL-------EYKTLSKEFEALMAEKNT 1728
Cdd:TIGR02168  528 L--ISVDEG---YEAAIEAALG--GRLQAVVVENlnaakkaiAFLKQnELGRVTFlpldsikGTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1729 LSEETRNLKLQVEAQELKQASLETTEKSDEPKDVIEE----------VTE---------AVVGKSQEQDS--LSENAKLE 1787
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELakklrpgyriVTLdgdlvrpggVITGGSAKTNSsiLERRREIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1788 DAEATL--LANSAKPGVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLE 1865
Cdd:TIGR02168  681 ELEEKIeeLEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1866 EEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEERLMN---QLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCV 1942
Cdd:TIGR02168  761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1943 SELEEEKQQLVKEKTKVESEIRKEymekiqgaqkgpgsKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKAL 2022
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEEL--------------EELIEELESELEALLNERASLEEALALLRSELEELSEELREL 906

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2023 EFVHTESQKDLDATKgnlaqavEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLR 2102
Cdd:TIGR02168  907 ESKRSELRRELEELR-------EKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLEN 979

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 564376925  2103 RLEQ-------AEEKHRKEKknmqEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKEL 2153
Cdd:TIGR02168  980 KIKElgpvnlaAIEEYEELK----ERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1152-1965 8.96e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.26  E-value: 8.96e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1152 GKIVDLEKEKTQLQKKLQEALISRKAILKKAQEKEkhlkEELKEQKDAYRHLQEQFDGQSKENENIAARLRQLQA-KEST 1230
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQqKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1231 DQQLPGTGQQEPTHGSEGLSLEGTEPASESDLHAAqpshpgETATLQATVSVAQIQDQLKEIEVEKEELELKISSTTSEL 1310
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELESKLDELAEELAEL------EEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1311 TKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIADLE------HLKTLQPELETLQKHVGQKEE 1384
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkelqaELEELEEELEELQEELERLEE 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1385 EVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHEErLKQVQVEICELKKQPKELEEESKAKQQLQRKLQ 1464
Cdd:TIGR02168  462 ALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG-VKALLKNQSGLSGILGVLSELISVDEGYEAAIE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1465 AALISRKEALkenksLQEQLSSARDAVEHLTKS--------LADVESQVSVQNQEKDALLGKLALLQEERDKLIVEMDKS 1536
Cdd:TIGR02168  541 AALGGRLQAV-----VVENLNAAKKAIAFLKQNelgrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1537 LLENQSLGGS--CESLKLALGGL----------TEDKEKLMKELESVRCSKIAEST--EWQEKHKELQKEYEVLLQSYEN 1602
Cdd:TIGR02168  616 KALSYLLGGVlvVDDLDNALELAkklrpgyrivTLDGDLVRPGGVITGGSAKTNSSilERRREIEELEEKIEELEEKIAE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1603 VSNEaeriqhvVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQ 1682
Cdd:TIGR02168  696 LEKA-------LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1683 PVGGANESMEALLSSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQELKQASLETTeksdepkdv 1762
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR--------- 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1763 IEEVTEAVVGKSQEQDSLSEN-AKLEDAEATLlansakpgvsetfssHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQ 1841
Cdd:TIGR02168  840 LEDLEEQIEELSEDIESLAAEiEELEELIEEL---------------ESELEALLNERASLEEALALLRSELEELSEELR 904

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1842 TLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLK----ETAEEEKDDLEERLMNQLAELNGSIgny 1917
Cdd:TIGR02168  905 ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTleeaEALENKIEDDEEEARRRLKRLENKI--- 981

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 564376925  1918 yqdvtdAQIKNEQLES--EMQNLKRCVSELEEEKQQLVKEKTKVESEIRK 1965
Cdd:TIGR02168  982 ------KELGPVNLAAieEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1426-2296 2.31e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 80.11  E-value: 2.31e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1426 KEHEERLKQVQVEICELKKQPKELEEEsKAKQQLQRKLQAALISRK--EALKENKSLQEQLSSARDAVEHLTKSLADVES 1503
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEgyELLKEKEALERQKEAIERQLASLEEELEKLTE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1504 QVSVQNQEKDALLGKLALLQEERDKLIVEMDKSLLEN-QSLGGSCESLKLALggltEDKEKLMKELESVRCSKIAESTEW 1582
Cdd:TIGR02169  259 EISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSI----AEKERELEDAEERLAKLEAEIDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1583 QEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKS 1662
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEE 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1663 KQQKILELEEENDRLRAEAQPVGGANESMEALLSSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEA 1742
Cdd:TIGR02169  415 LQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1743 QELKQASLETTEKSDEP-KDVIEEVTEAVVGKSQEQDSLSEN--AKLEDAEATLLANSakpgVSETFSSHDDINNYLQQL 1819
Cdd:TIGR02169  495 AEAQARASEERVRGGRAvEEVLKASIQGVHGTVAQLGSVGERyaTAIEVAAGNRLNNV----VVEDDAVAKEAIELLKRR 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1820 DqlKGRIAELEMEKQKDRELSQTLENEKNALltqisakDSELKLLEEEvakinmlnQQIQEELSRVtkLKETAEEEKDDL 1899
Cdd:TIGR02169  571 K--AGRATFLPLNKMRDERRDLSILSEDGVI-------GFAVDLVEFD--------PKYEPAFKYV--FGDTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1900 EERLMNQ---------LAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIrKEYMEK 1970
Cdd:TIGR02169  632 ARRLMGKyrmvtlegeLFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRL-DELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1971 IQGAQKgpgsKIHAKELQ-ELLKEKQQEVKQLQKDCIRYlgrISALEKTVKALEfvhtESQKDLDATKGNLAQAVEHHKK 2049
Cdd:TIGR02169  711 LSDASR----KIGEIEKEiEQLEQEEEKLKERLEELEED---LSSLEQEIENVK----SELKELEARIEELEEDLHKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2050 AQAELSSfkillDDTQSEAARVLADNLKLKKELQSNkESIKSQIKQKDEDLLRRLEQAEekhrKEKKNMQEKLDALHREK 2129
Cdd:TIGR02169  780 ALNDLEA-----RLSHSRIPEIQAELSKLEEEVSRI-EARLREIEQKLNRLTLEKEYLE----KEIQELQEQRIDLKEQI 849

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2130 AHVEDTLAEIQVSLTRKDKDMKELQqsldstlAQLAAFTKSMSSLQDDRDRVIDEAKKWEQRfgdaIQTKEEEVRLKEEN 2209
Cdd:TIGR02169  850 KSIEKEIENLNGKKEELEEELEELE-------AALRDLESRLGDLKKERDELEAQLRELERK----IEELEAQIEKKRKR 918

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2210 CTALKDQLRQMTIHMEELKITVSRLEHDKEIWES--KAQTELQHQQKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKL 2287
Cdd:TIGR02169  919 LSELKAKLEALEEELSEIEDPKGEDEEIPEEELSleDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKL 998


                   ....*....
gi 564376925  2288 ESELKSLKD 2296
Cdd:TIGR02169  999 EEERKAILE 1007
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1347-1914 7.07e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 7.07e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1347 QLKQELESSQLKIAdLEHLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAK 1426
Cdd:COG1196   217 ELKEELKELEAELL-LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1427 EHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSLADVESQVS 1506
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1507 VQNQEKDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESVRcskiAESTEWQEKH 1586
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE----EALEEAAEEE 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1587 KELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQK 1666
Cdd:COG1196   452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1667 ILELEEENDRLRAEAQPVGGANESMEALLSSNASLKEE-LERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQE- 1744
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREa 611

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1745 --------------------LKQASLETTEKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKPGVSE 1804
Cdd:COG1196   612 daryyvlgdtllgrtlvaarLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1805 TFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSR 1884
Cdd:COG1196   692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 564376925 1885 VTKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1914
Cdd:COG1196   772 LEREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 749-1234 2.05e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 2.05e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  749 DVLGELRAQVRELE---------TSLAEAEKQR-----GLDYESQRAQHNLLTEQIHSLSIEAKS-------KDVKIETL 807
Cdd:COG1196   193 DILGELERQLEPLErqaekaeryRELKEELKELeaellLLKLRELEAELEELEAELEELEAELEEleaelaeLEAELEEL 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  808 QRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQ-- 885
Cdd:COG1196   273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEee 352

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  886 -QTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAESSPKHGPHESSAQEpvc 964
Cdd:COG1196   353 lEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA--- 429

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  965 KDALQQELEWLRKESEQRKRKLQAALISRKELLQKVSKLEEELAKVREESTKDSLRESEKRELEEDSKNKDDPEKYGTSE 1044
Cdd:COG1196   430 LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEG 509

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1045 WRELEVSLRLTISEKEVELEGIRRDLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEE------------ITENQATI 1112
Cdd:COG1196   510 VKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratflpldkIRARAALA 589

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1113 QKFITGTMDAG-----------------DGDSAVKETSVSSppRAGGGEHWKPELEGKIVDLEKEKTQLQKKLQEALISR 1175
Cdd:COG1196   590 AALARGAIGAAvdlvasdlreadaryyvLGDTLLGRTLVAA--RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR 667

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564376925 1176 KAILKKAQEKEKHLKEELKEQKDAYRHLQEQFDGQSKENENIAARLRQLQAKESTDQQL 1234
Cdd:COG1196   668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEAL 726
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1816-2587 2.58e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 76.65  E-value: 2.58e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1816 LQQLDQLKGRIAELEMEKQKDRELSQT----LENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKET 1891
Cdd:TIGR02169  197 RQQLERLRREREKAERYQALLKEKREYegyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEE 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1892 AEEEKDDLEERLMNQL-----------AELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVE 1960
Cdd:TIGR02169  277 LNKKIKDLGEEEQLRVkekigeleaeiASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1961 SEI---RKEYMEKIQGAQ----KGPGSKIHAKELQELLKEKQQEVKQLQKDCIRYLGR--------------ISALEKTV 2019
Cdd:TIGR02169  357 EEYaelKEELEDLRAELEevdkEFAETRDELKDYREKLEKLKREINELKRELDRLQEElqrlseeladlnaaIAGIEAKI 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2020 KALEFVHTESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLD---DTQSEAARVLADNLKLKKELQSNKESIKSQIKQK 2096
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDrveKELSKLQRELAEAEAQARASEERVRGGRAVEEVL 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2097 DED------LLRRLEQAEEKHR----------------KEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDK------ 2148
Cdd:TIGR02169  517 KASiqgvhgTVAQLGSVGERYAtaievaagnrlnnvvvEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLsilsed 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2149 -------DMKELQQSLDSTLAQLAAFTKSMSSLQDDRD-----RVIDEAKKWEQRFGdAIQTKEEEVRLKEENCTALKDQ 2216
Cdd:TIGR02169  597 gvigfavDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRlmgkyRMVTLEGELFEKSG-AMTGGSRAPRGGILFSRSEPAE 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2217 LRQMTIHMEELKITVSRLEHDKEiwesKAQTELQHQQKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLESELKSLKD 2296
Cdd:TIGR02169  676 LQRLRERLEGLKRELSSLQSELR----RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2297 QSTDLKNSLEKcrehennLEGIIKQQEADIQNCKFNCEQLETDLtaSRELTTRLHDEINvKEQKIISLLSGKEEAIQVAI 2376
Cdd:TIGR02169  752 EIENVKSELKE-------LEARIEELEEDLHKLEEALNDLEARL--SHSRIPEIQAELS-KLEEEVSRIEARLREIEQKL 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2377 AELHQQHSKEIKELENLLSQEEEENLTLEEENKRaVEKTNQLTEALETIKKESLEQKAQLDsfvKSMSSLQDDRDRIVSD 2456
Cdd:TIGR02169  822 NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE-IENLNGKKEELEEELEELEAALRDLE---SRLGDLKKERDELEAQ 897

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2457 YRQLEERhlsvilekdelIQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVITIKDSQ-QRQLLEAQ 2535
Cdd:TIGR02169  898 LRELERK-----------IEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQaELQRVEEE 966

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|..
gi 564376925  2536 LQQNKELRNecvKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQ 2587
Cdd:TIGR02169  967 IRALEPVNM---LAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1929-2742 5.16e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.49  E-value: 5.16e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1929 EQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGpgsKIHAKELQELLKEKQQ---EVKQLQKDC 2005
Cdd:TIGR02169  177 EELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEG---YELLKEKEALERQKEAierQLASLEEEL 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2006 IRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAVehhKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSN 2085
Cdd:TIGR02169  254 EKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRV---KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2086 KESIKSQIKQKDEDLlrrleqaeEKHRKEKKNMQEKLDALhrekahvEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLA 2165
Cdd:TIGR02169  331 IDKLLAEIEELEREI--------EEERKRRDKLTEEYAEL-------KEELEDLRAELEEVDKEFAETRDELKDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2166 AFTKSMSSLQDDRDRVIDEAKKWEQRFGDAiqtkEEEVRLKEENCTALKDQLRQMTIHMEELKITVSRLEHDKEiwesKA 2245
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADL----NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS----KY 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2246 QTELQHQQKAYDKLQEENKELMSQLEEAgqlyhdsKNELTKLESELKSLKDQSTDLKNSLE----------KCREHE--- 2312
Cdd:TIGR02169  468 EQELYDLKEEYDRVEKELSKLQRELAEA-------EAQARASEERVRGGRAVEEVLKASIQgvhgtvaqlgSVGERYata 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2313 ------NNLEGIIKQQEADIQNC------------------KFNCEQLETDLTASRELTTRLHDEINVKEQK-------- 2360
Cdd:TIGR02169  541 ievaagNRLNNVVVEDDAVAKEAiellkrrkagratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYepafkyvf 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2361 -----IISLLSGKEEAIQVAIAELHQ---QHSKEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALETIKKESLEQ 2432
Cdd:TIGR02169  621 gdtlvVEDIEAARRLMGKYRMVTLEGelfEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2433 KAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSVilekDELIQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQ 2512
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKL----KERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHK 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2513 YRRDLNEvitIKDSQQRQLLEAQLQQNKELRNECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALH 2592
Cdd:TIGR02169  777 LEEALND---LEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2593 EEgaLAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKVSEIEDkLKRELKHLHHNAGIMRNETETAE 2672
Cdd:TIGR02169  854 KE--IENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE-LEAQIEKKRKRLSELKAKLEALE 930

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2673 ERVAELARDLVEMEQKLLTVTKEnKDLTAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQLK 2742
Cdd:TIGR02169  931 EELSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLE 999
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 317-1114 7.38e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 7.38e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   317 EAERQESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQYGTLQQrhetEMEEKTACISLLQKNEQELQSACDA 396
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQK----ELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   397 LKEENSKLlqeqQEQAAKSAQALQQLEDELQQKSKEISQFVNKPNLEKHETSSQtslpdvynEGVQAVMEESVASLQKrv 476
Cdd:TIGR02168  314 LERQLEEL----EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL--------EAELEELESRLEELEE-- 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   477 lELENEKGALLLSSLELEELRAENEKLCSRITLLEA--QNRAGEADGMVCEVSTAGIALLnRSDSSTEESGQDVLENTFS 554
Cdd:TIGR02168  380 -QLETLRSKVAQLELQIASLNNEIERLEARLERLEDrrERLQQEIEELLKKLEEAELKEL-QAELEELEEELEELQEELE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   555 QKHKELSVLLVEMKEAQEEIAFLKSQLQGKRPEGDYEVLDRKEVQ---------MMESEGLPSVTAR---DVLCAPRDKN 622
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkalLKNQSGLSGILGVlseLISVDEGYEA 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   623 SVPA----------VEGEQAGMRDQHGTLEAGPLNDTGMELNSPQPDGVDKS-LSAPHVCLCHQGELERLKTQ------- 684
Cdd:TIGR02168  538 AIEAalggrlqavvVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNdREILKNIEGFLGVAKDLVKFdpklrka 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   685 ----------VLELETSLHTAKETHEK--------------------------NLSEKAKEISSLTQLTKEFKESAEEAR 728
Cdd:TIGR02168  618 lsyllggvlvVDDLDNALELAKKLRPGyrivtldgdlvrpggvitggsaktnsSILERRREIEELEEKIEELEEKIAELE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   729 STLTAVCEERDQLlyrvkeLDVLGELRAQVRELETSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAKSKDVKIETLQ 808
Cdd:TIGR02168  698 KALAELRKELEEL------EEELEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   809 RELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTI 888
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   889 QEkdqqvtelsfsMTEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAEsspkhgphessaqepvcKDAL 968
Cdd:TIGR02168  848 EE-----------LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE-----------------LEEL 899

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   969 QQELewlrKESEQRKRKLQAALISRKELLQKVsKLEEELAKVREESTKDSLRESEKRELEEDSKNKDDPEKYgTSEWREl 1048
Cdd:TIGR02168  900 SEEL----RELESKRSELRRELEELREKLAQL-ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDD-EEEARR- 972

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1049 evslrltisekevELEGIRRDLKE----KAAAEEELQALVQRmtqdLQNKTKQIDLLQEEITENQATIQK 1114
Cdd:TIGR02168  973 -------------RLKRLENKIKElgpvNLAAIEEYEELKER----YDFLTAQKEDLTEAKETLEEAIEE 1025
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 803-1736 1.02e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.71  E-value: 1.02e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   803 KIETLQRELDGVQLQFSEQGTQIRSLQSQLQTkesevlegAERMKDISKEMEELSQALSQKELE--IAQMDQLLLEKKK- 879
Cdd:TIGR02168  180 KLERTRENLDRLEDILNELERQLKSLERQAEK--------AERYKELKAELRELELALLVLRLEelREELEELQEELKEa 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   880 --DVETLQQTIQEKDQQVTEL---SFSMTEKMVQLNEEKFSLGVEIKTLKEQlsllsraegakkeqvedsgaesspkhgp 954
Cdd:TIGR02168  252 eeELEELTAELQELEEKLEELrleVSELEEEIEELQKELYALANEISRLEQQ---------------------------- 303

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   955 hessaqepvcKDALQQELEWLRKESEQRKRKLQAALISRKELLQKVSKLEEELAKVREESTKDSLRESEKRELEEDSKNK 1034
Cdd:TIGR02168  304 ----------KQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1035 ddpekygtsewrelevslrltISEKEVELEGIRRDLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEEITENQATIQk 1114
Cdd:TIGR02168  374 ---------------------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE- 431

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1115 fitgtmdagdgdsavketsvssppragggEHWKPELEGKIVDLEKEKTQLQKKL---QEALISRKAILKKAQEKEKHLKE 1191
Cdd:TIGR02168  432 -----------------------------EAELKELQAELEELEEELEELQEELerlEEALEELREELEEAEQALDAAER 482

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1192 ELKEQKDAYRHLQEQFDGQSKENENIAARLRQLQAKESTDQQLpgtgqqepthgSEGLSL-EGTEPASESDL--HAAQPS 1268
Cdd:TIGR02168  483 ELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVL-----------SELISVdEGYEAAIEAALggRLQAVV 551

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1269 HPGETATLQATVSVAQIQDQLKEIEVEKEELELKISSTTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQL 1348
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1349 KQELESSQlKIADLEHLKTLQPELETLQKHVGQKEEEVSylvGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEH 1428
Cdd:TIGR02168  632 DNALELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTN---SSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1429 EE---RLKQVQVEICELKKQ----PKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSLADV 1501
Cdd:TIGR02168  708 EEleeELEQLRKELEELSRQisalRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1502 ESQVSVQNQEKDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESVRcskiAESTE 1581
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLA----AEIEE 863

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1582 WQEKHKELQKEYEVLLqsyenvsNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFak 1661
Cdd:TIGR02168  864 LEELIEELESELEALL-------NERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL-- 934

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1662 skQQKILELEEendRLRAEAQ-PVGGANESMEALLSSNASLKEELERITL--------------EYKTLSKEFEALMAEK 1726
Cdd:TIGR02168  935 --EVRIDNLQE---RLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaaieEYEELKERYDFLTAQK 1009

                          970
                   ....*....|
gi 564376925  1727 NTLSEETRNL 1736
Cdd:TIGR02168 1010 EDLTEAKETL 1019
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1276-1860 1.10e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.59  E-value: 1.10e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1276 LQATVSVAQIQDQLKEIEVEKE---ELELKISSTTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQEL 1352
Cdd:COG1196   225 LEAELLLLKLRELEAELEELEAeleELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1353 ESSQLKIADLEH-LKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHEER 1431
Cdd:COG1196   305 ARLEERRRELEErLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEEL 384

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1432 LKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSLADVESQVSVQNQE 1511
Cdd:COG1196   385 AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1512 KDALLGKLALLQEERDKLIVEMDKSLLENQSLGgscESLKLALGGLTEDKEKLMKELESVRCSKIAESTEWQEKHKELQK 1591
Cdd:COG1196   465 LAELLEEAALLEAALAELLEELAEAAARLLLLL---EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALE 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1592 EYEVLLQSYENVSNEAERIQHVVESVRQEKQEVY------AKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQ 1665
Cdd:COG1196   542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATflpldkIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1666 KILELEEENDRLRAEAQPVGGANESMEALLSSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQEL 1745
Cdd:COG1196   622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1746 KQASLETTEKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKPGVSEtfsshdDINNYLQQLDQLKGR 1825
Cdd:COG1196   702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP------DLEELERELERLERE 775

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*....
gi 564376925 1826 IAEL---------EMEKQKDR--ELS---QTLENEKNALLTQISAKDSE 1860
Cdd:COG1196   776 IEALgpvnllaieEYEELEERydFLSeqrEDLEEARETLEEAIEEIDRE 824
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1728-2297 1.35e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 1.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1728 TLSEETRNLKLQVEAQELKQASLETTEKSDEpKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKpgvSETFS 1807
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELEAELEELEAE-LEELEAELEELEAELAELEAELEELRLELEELELELEEAQ---AEEYE 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1808 SHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTK 1887
Cdd:COG1196   293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1888 LKETAEEEKDDLEERLMNQLAELNgsigNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEY 1967
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAA----ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1968 MEKIQGAQKgpgsKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAVEHH 2047
Cdd:COG1196   449 EEEAELEEE----EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2048 KKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEK-----L 2122
Cdd:COG1196   525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGaavdlV 604

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2123 DALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWEQRFGDAIQTKEEE 2202
Cdd:COG1196   605 ASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2203 VRLKEENCTALKDQLRQMtihmEELKITVSRLEHDKEIWESKAQTELQHQQKAYDKLQEENKELMSQLEEAGQLYHDSKN 2282
Cdd:COG1196   685 AERLAEEELELEEALLAE----EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP 760

                         570
                  ....*....|....*
gi 564376925 2283 ELTKLESELKSLKDQ 2297
Cdd:COG1196   761 DLEELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2197-2741 1.37e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 1.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2197 QTKEEEVRLKEENCTALKDQLRQMTIhmEELKITVSRLEHDKEiwesKAQTELQHQQKAYDKLQEENKELMSQLEEAGQL 2276
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2277 YHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNCKFNCEQLETDLTASRELTTRLHDEINV 2356
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2357 KEQKIISLLSgKEEAIQVAIAELHQQHSKEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQL 2436
Cdd:COG1196   370 AEAELAEAEE-ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2437 DSFVKSMSSLQDDRDRIVSDYRQLEERHLSVILEKDELIQDAAAEN------------------NKLKEEIRGLRGHMDD 2498
Cdd:COG1196   449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLllleaeadyegflegvkaALLLAGLRGLAGAVAV 528

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2499 LNSENAKLDAELIQYRRDLNEVITIKDSQQRQLLEAQLQQNKELRNECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLS 2578
Cdd:COG1196   529 LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL 608

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2579 KEIKSFKEQLTALHEEGALAV--------YHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKVSEIEDKL 2650
Cdd:COG1196   609 READARYYVLGDTLLGRTLVAarleaalrRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2651 KRELKHLHHNAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLTAQIQAFGKSMSSLQDSRDHATEELSDLKKK 2730
Cdd:COG1196   689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768

                         570
                  ....*....|.
gi 564376925 2731 YDASLKELAQL 2741
Cdd:COG1196   769 LERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 61-582 1.57e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 1.57e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   61 LELKDIISKQDAQLQ-QKDEALQEEKKGAESKIKKIKL---HAKAKITSLNKQIEELKTQGGAASppevqaEELSKHDKS 136
Cdd:COG1196   216 RELKEELKELEAELLlLKLRELEAELEELEAELEELEAeleELEAELAELEAELEELRLELEELE------LELEEAQAE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  137 STEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEKEELIGALQTQLSQTQAEQAA 216
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  217 QLSSMQQVVREKDARFETQVRLhEDELLQLVTQsdvETEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQ 296
Cdd:COG1196   370 AEAELAEAEEELEELAEELLEA-LRAAAELAAQ---LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  297 DLSQQLQLLEAEHSTLRNTMEAERQESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEmqyGTLQQRHETEMEEK 376
Cdd:COG1196   446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLE---GVKAALLLAGLRGL 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  377 TACISLLQKNEQELQSACDALkeenskLLQEQQEQAAKSAQALQQLEDELQQKSKEISQFVNKPNLEKHETSSQTSLPDV 456
Cdd:COG1196   523 AGAVAVLIGVEAAYEAALEAA------LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA 596

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  457 YNEGVQAVMEESVASLQKRVLELENEKGALLLSSLELEELRAEnEKLCSRITLLEAQNRAGEADGMvcevSTAGIALLNR 536
Cdd:COG1196   597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRA-VTLAGRLREVTLEGEGGSAGGS----LTGGSRRELL 671

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 564376925  537 SDSSTEESGQDVLENTFSQKHKELSVLLVEMKEAQEEIAFLKSQLQ 582
Cdd:COG1196   672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1584-2153 3.02e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.05  E-value: 3.02e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1584 EKHKELQKEYEVL-----LQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRK 1658
Cdd:COG1196   213 ERYRELKEELKELeaellLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1659 FAKSKQQKILELEEENDRLRAEAQPVGGANESMEALLSSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKL 1738
Cdd:COG1196   293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1739 QVEAQELKQASLETTEKSDEpKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKpgvsetfsshdDINNYLQQ 1818
Cdd:COG1196   373 ELAEAEEELEELAEELLEAL-RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE-----------LEEEEEEE 440

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1819 LDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDD 1898
Cdd:COG1196   441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1899 LEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEmQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGP 1978
Cdd:COG1196   521 GLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDD-EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1979 GSKIHAKELQELLKEKQQEVKQL------QKDCIRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAVEHHKKAQA 2052
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLlgrtlvAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2053 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKdEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2132
Cdd:COG1196   680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEE-EALEEQLEAEREELLEELLEEEELLEEEALEELPE 758

                         570       580
                  ....*....|....*....|.
gi 564376925 2133 EDTLAEIQVSLTRKDKDMKEL 2153
Cdd:COG1196   759 PPDLEELERELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 707-1489 3.90e-12

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 72.87  E-value: 3.90e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  707 AKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLYRVKELDvlgelraQVRELEtslaEAEKQRgldyESQRAQHNLL 786
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAE-------DARKAE----EARKAE----DARKAEEARK 1147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  787 TEQIHSLSIEAKSKDV-KIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKeMEELSQALSQKEL 865
Cdd:PTZ00121 1148 AEDAKRVEIARKAEDArKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERK-AEEARKAEDAKKA 1226

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  866 EIAQMDQlllEKKKDVETLQQTiqEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQlslLSRAEGAKKEQvEDSG 945
Cdd:PTZ00121 1227 EAVKKAE---EAKKDAEEAKKA--EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADE---LKKAEEKKKAD-EAKK 1297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  946 AESSPKHGPHESSAQEPVCKDALQQELEWLRKESEQRKRKLQAAlisrkellqkvsKLEEELAKVREESTKDSLRESEKR 1025
Cdd:PTZ00121 1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEA------------KKAAEAAKAEAEAAADEAEAAEEK 1365

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1026 ELEEDSKNKDDPEKYGTSEWRELEVSLRLTISEKEVELEGIRRDLKEKAAAEEELQALVQRMTQdlqnkTKQIDLLQEEI 1105
Cdd:PTZ00121 1366 AEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEE-----KKKADEAKKKA 1440

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1106 TENQATiqkfitgtmdagdgdsavKETSVSSPPRAGGGEHWKPELEGKIVDLEKEKTQLQKKLQEALISRKAILKKAQEK 1185
Cdd:PTZ00121 1441 EEAKKA------------------DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1186 EKhlKEELKEQKDAYRHLQEQFDGQSKENENIAARLRQLQAKESTDQQLPGTGQQEPTHGSEGLSLEGTEPASESDLHAA 1265
Cdd:PTZ00121 1503 KK--AAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMAL 1580

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1266 QPSHPGETATLQATVSVAQIQDQLKEIEVEKEELELKISSTTSELTKKSEE---VLLLQEQINEQGLEIQNLKAASHEAK 1342
Cdd:PTZ00121 1581 RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEkkkVEQLKKKEAEEKKKAEELKKAEEENK 1660

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1343 AHTEQLKQELESSQLKIADLEHlktlQPELETLQKHVGQKEEEVSYLVGQL--GEKEQTLTTVQTEMEEQERLIKAlhTQ 1420
Cdd:PTZ00121 1661 IKAAEEAKKAEEDKKKAEEAKK----AEEDEKKAAEALKKEAEEAKKAEELkkKEAEEKKKAEELKKAEEENKIKA--EE 1734

                         730       740       750       760       770       780
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564376925 1421 LEMQAKEHEERLKQVQVEICElKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARD 1489
Cdd:PTZ00121 1735 AKKEAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKD 1802
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1429-2001 4.38e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 4.38e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1429 EERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSLADVESQVSVQ 1508
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1509 NQEKDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESVRCSKIAESTEWQEKHKE 1588
Cdd:COG1196   301 EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1589 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVyAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKIL 1668
Cdd:COG1196   381 LEELAEELLEALRAAAELAAQLEELEEAEEALLERL-ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1669 ELEEENDRLRAEAqpvgganesmEALLSSNASLKEELERITLEYKTLskefEALMAEKNTLSEETRNLKLQVEAQELKQA 1748
Cdd:COG1196   460 ALLELLAELLEEA----------ALLEAALAELLEELAEAAARLLLL----LEAEADYEGFLEGVKAALLLAGLRGLAGA 525

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1749 SLETTEKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEAT-------LLANSAKPGVSETFSSHDDINNYLQQLDQ 1821
Cdd:COG1196   526 VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratfLPLDKIRARAALAAALARGAIGAAVDLVA 605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1822 LKGRIAELEMEKQKDRELSQTLENEKNALLTQISAK-DSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLE 1900
Cdd:COG1196   606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTlAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1901 ERLMNQLAELNgsignyyQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPGS 1980
Cdd:COG1196   686 ERLAEEELELE-------EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPE 758

                         570       580
                  ....*....|....*....|.
gi 564376925 1981 KIHAKELQELLKEKQQEVKQL 2001
Cdd:COG1196   759 PPDLEELERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1309-2003 5.42e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 5.42e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1309 ELTKKSEEVLLLQEQINEQ--GLEIQNLKAASHEA-KAHTEQLKQELESSQLKIADlEHLKTLQPELETLQKHVGQKEEE 1385
Cdd:TIGR02169  181 EVEENIERLDLIIDEKRQQleRLRREREKAERYQAlLKEKREYEGYELLKEKEALE-RQKEAIERQLASLEEELEKLTEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1386 VSYLVGQLGEKEQTLTTVQTEM-----EEQERLIKALHT-------------QLEMQAKEHEERLKQVQVEICELKKQPK 1447
Cdd:TIGR02169  260 ISELEKRLEEIEQLLEELNKKIkdlgeEEQLRVKEKIGEleaeiaslersiaEKERELEDAEERLAKLEAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1448 ELEEESKAKQQLQRKLQAALISRKEalKENKSLQEqlssardavehltksLADVESQVSVQNQEKDALLGKLALLQEERD 1527
Cdd:TIGR02169  340 ELEREIEEERKRRDKLTEEYAELKE--ELEDLRAE---------------LEEVDKEFAETRDELKDYREKLEKLKREIN 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1528 KLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKeklmKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEA 1607
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELADLNAAIAGIEAKI----NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1608 ERIQHVVESVRQEKQEVYAKLRSAESDKREREKQ------------------------------------LQDAEQEMEE 1651
Cdd:TIGR02169  479 DRVEKELSKLQRELAEAEAQARASEERVRGGRAVeevlkasiqgvhgtvaqlgsvgeryataievaagnrLNNVVVEDDA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1652 MKEKMRKFAKSKQ---------QKI-------------------LELEEENDRLRAEAQPVGGANESMEALLSSNAsLKE 1703
Cdd:TIGR02169  559 VAKEAIELLKRRKagratflplNKMrderrdlsilsedgvigfaVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARR-LMG 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1704 ELERITLEYKTLSKE-------FEALMAEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAVVGKSQE 1776
Cdd:TIGR02169  638 KYRMVTLEGELFEKSgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRK 717

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1777 QDSLSENAKLEDAEATLLANSAKPGVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNAllTQISA 1856
Cdd:TIGR02169  718 IGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPE 795

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1857 KDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMQ 1936
Cdd:TIGR02169  796 IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELE 871

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925  1937 NLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPGSKIHAKELQELLKEKQQEVKQLQK 2003
Cdd:TIGR02169  872 ELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIED 938
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2048-2613 6.14e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 6.14e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2048 KKAQAELSSFKIllDDTQSEAARVLADnlklKKELQSNKESIKSQIkQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHR 2127
Cdd:COG1196   223 KELEAELLLLKL--RELEAELEELEAE----LEELEAELEELEAEL-AELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2128 EKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWEQRFGDAIQTKEEEVRLKE 2207
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2208 ENCTALKDQLRQMTIHMEELKITVSRLEHDKEIWESKAQtELQHQQKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKL 2287
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE-RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2288 ESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEAdiqnckfnceQLETDLTASRELTTRLHDeinVKEQKIISLLSG 2367
Cdd:COG1196   455 EEEEEALLELLAELLEEAALLEAALAELLEELAEAAA----------RLLLLLEAEADYEGFLEG---VKAALLLAGLRG 521

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2368 KEEAIQVAIAELHQQhSKEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEA----LETIKKESLEQKAQLDSFVKSM 2443
Cdd:COG1196   522 LAGAVAVLIGVEAAY-EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAtflpLDKIRARAALAAALARGAIGAA 600

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2444 SSLQDDRDRIVSDYRQLEERHLSVILEKDELIQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVITI 2523
Cdd:COG1196   601 VDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2524 KDSQQRQLLEAQLQQNKELRNEcvkLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHEEGALAVYHAQ 2603
Cdd:COG1196   681 LEELAERLAEEELELEEALLAE---EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELP 757

                         570
                  ....*....|
gi 564376925 2604 LRVREEEVQK 2613
Cdd:COG1196   758 EPPDLEELER 767
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 72-898 7.04e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.02  E-value: 7.04e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925    72 AQLQQKDEALQEEKKGAESKIKKIKLhakaKITSLNKQIEELKTQggaasppevqAEELSKHDKSSTE-EEMEVEKIKHE 150
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDL----IIDEKRQQLERLRRE----------REKAERYQALLKEkREYEGYELLKE 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   151 LQEKEKLISNLQAQLDQAQSEqasqLDKSSAEMEDfvlMRQKLQEKEELIGALQTQLSQTQAEQAAQLSSMQQVVREKDA 230
Cdd:TIGR02169  232 KEALERQKEAIERQLASLEEE----LEKLTEEISE---LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   231 RFETQVRLHEDELLQLVTQsdvETEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQLQLLEAEHS 310
Cdd:TIGR02169  305 SLERSIAEKERELEDAEER---LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   311 TLRNTMEAERQEskilMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQYGTLQQRHETEMEEKTACISLLQKNEQEL 390
Cdd:TIGR02169  382 ETRDELKDYREK----LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   391 QSACDALKEENSKLLQEQQEqaaksaqaLQQLEDELQQKSKEISQfvnkpnLEKHETSSQTSLPdvYNEGVQAVMEESVA 470
Cdd:TIGR02169  458 EQLAADLSKYEQELYDLKEE--------YDRVEKELSKLQRELAE------AEAQARASEERVR--GGRAVEEVLKASIQ 521

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   471 SLQKRVLELENEKGALLLSSLELEELRaeneklcsritlleAQNRAGEADGmvceVSTAGIALLNRSDSSteeSGQDVLE 550
Cdd:TIGR02169  522 GVHGTVAQLGSVGERYATAIEVAAGNR--------------LNNVVVEDDA----VAKEAIELLKRRKAG---RATFLPL 580

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   551 NTFSQKHKELSVLLveMKEAQEEIAFLKSQLQGKRPEGDYEVLDRKEVQMMEseglpsvTARDVLcaprDKNSVPAVEGE 630
Cdd:TIGR02169  581 NKMRDERRDLSILS--EDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDIE-------AARRLM----GKYRMVTLEGE 647

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   631 qagMRDQHGTLEAGPLNDTGMELNSPQPDGVDKSLSAPHVCLchQGELERLKTQVLELETSLHTAK---ETHEKNLSEKA 707
Cdd:TIGR02169  648 ---LFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGL--KRELSSLQSELRRIENRLDELSqelSDASRKIGEIE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   708 KEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLYRVKELD--------VLGELRAQVRELETSLAEAE-KQRGLDYES 778
Cdd:TIGR02169  723 KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEarieeleeDLHKLEEALNDLEARLSHSRiPEIQAELSK 802

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   779 QRAQHNLLTEQIHSLSIEAKSKDV-------KIETLQRELDGVQLQFSEQG-------TQIRSLQSQLQTKESEVLEGAE 844
Cdd:TIGR02169  803 LEEEVSRIEARLREIEQKLNRLTLekeylekEIQELQEQRIDLKEQIKSIEkeienlnGKKEELEEELEELEAALRDLES 882

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 564376925   845 RMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTIQEKDQQVTEL 898
Cdd:TIGR02169  883 RLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEI 936
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1693-2489 1.77e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 1.77e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1693 ALLSSNASLKEELERITLEYKTLSKEFEALMAEKntlseETRNLKLQVEAQELKQASLETTEK-SDEPKDVIEEVTEAVV 1771
Cdd:TIGR02169  227 ELLKEKEALERQKEAIERQLASLEEELEKLTEEI-----SELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEA 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1772 GKSQEQDSLSENA-KLEDAEATLLANSAkpgvsetfsshdDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNAL 1850
Cdd:TIGR02169  302 EIASLERSIAEKErELEDAEERLAKLEA------------EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDL 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1851 LTQISAKDSELKLLEEEVA----KINMLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQLAELNGSIGNYYQDVTDAQI 1926
Cdd:TIGR02169  370 RAELEEVDKEFAETRDELKdyreKLEKLKREINELKRELDRLQEELQRLSEELAD-LNAAIAGIEAKINELEEEKEDKAL 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1927 KNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRK---EYMEKIQGAQKGPGSKIHAKELQELLKEKQQEVKQLQK 2003
Cdd:TIGR02169  449 EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKlqrELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVA 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2004 DCIRYLGR-ISALE--------KTVKALEFVHTESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLD------------ 2062
Cdd:TIGR02169  529 QLGSVGERyATAIEvaagnrlnNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDgvigfavdlvef 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2063 DTQSEAA-------RVLADNLKLKKELQSNKESI--------KSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHR 2127
Cdd:TIGR02169  609 DPKYEPAfkyvfgdTLVVEDIEAARRLMGKYRMVtlegelfeKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKR 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2128 EkahvedtLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWEQRfgdaIQTKEEEVRLKE 2207
Cdd:TIGR02169  689 E-------LSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED----LSSLEQEIENVK 757

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2208 ENCTALKDQLRQMTIHMEELKITVSRLEhdkeiwESKAQTELQHQQKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKL 2287
Cdd:TIGR02169  758 SELKELEARIEELEEDLHKLEEALNDLE------ARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2288 ESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNCKFNCEQLETDLTASRELTTRLHDEINVKEQKIisllsg 2367
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI------ 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2368 KEEAIQVAIAELHQQHSKEikELENLLSQeeeenLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQ 2447
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKA--KLEALEEE-----LSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAI 978

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 564376925  2448 DDRDRIVSDYRQLEERHLSVILEKDElIQDAAAENNKLKEEI 2489
Cdd:TIGR02169  979 QEYEEVLKRLDELKEKRAKLEEERKA-ILERIEEYEKKKREV 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 224-1136 2.55e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 2.55e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   224 VVREKDARFETQVRLHE-DELLQLVTqsDVETEVQQKLRVMQRKLEEHEEALLGRAQV----VDLLQKELTSAEQRNQDL 298
Cdd:TIGR02168  167 ISKYKERRKETERKLERtRENLDRLE--DILNELERQLKSLERQAEKAERYKELKAELreleLALLVLRLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   299 SQQLQLLEAEHSTLrntmEAERQESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQYGTLQQRhetemeekta 378
Cdd:TIGR02168  245 QEELKEAEEELEEL----TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER---------- 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   379 cislLQKNEQELQSACDALKEENSKLlQEQQEQAAKSAQALQQLEDELQQKSKEISQFVNK-PNLEKHETSSQTSLPDVY 457
Cdd:TIGR02168  311 ----LANLERQLEELEAQLEELESKL-DELAEELAELEEKLEELKEELESLEAELEELEAElEELESRLEELEEQLETLR 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   458 NEgvQAVMEESVASLQKRVLELENEKGALLLSSLELEELRAENEKLCSRITLLEAQNRAGEADGMVCEVSTAGIALLNRS 537
Cdd:TIGR02168  386 SK--VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEAL 463

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   538 DSSTEEsgqdvlentFSQKHKELSVLLVEMKEAQEEIAFLKSQLQGKR--PEGDYEVLDRKEvqmmESEGLPSVTARDVL 615
Cdd:TIGR02168  464 EELREE---------LEEAEQALDAAERELAQLQARLDSLERLQENLEgfSEGVKALLKNQS----GLSGILGVLSELIS 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   616 CAPRDKNSVPAVEGEQAGmrdqhgtleagplndtgmelnspqpDGVDKSLSAPHVCLCHQGELERLKTQVLELETSLHTA 695
Cdd:TIGR02168  531 VDEGYEAAIEAALGGRLQ-------------------------AVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   696 KEtheKNLSEKAKEISSLTQLTKEFKESAEEARSTL------TAVCEERDQLLYRVKELDVL-------GEL-------- 754
Cdd:TIGR02168  586 IQ---GNDREILKNIEGFLGVAKDLVKFDPKLRKALsyllggVLVVDDLDNALELAKKLRPGyrivtldGDLvrpggvit 662

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   755 ------RAQVRELETSLAEAEKQRgldyesqraqhNLLTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSL 828
Cdd:TIGR02168  663 ggsaktNSSILERRREIEELEEKI-----------EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISAL 731

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   829 QSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTIQekdqqvtelsfsmtekmvQ 908
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE------------------Q 793

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   909 LNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAEsspkhgphessaqepvcKDALQQELEWLRKESEQRKRKLQA 988
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERR-----------------IAATERRLEDLEEQIEELSEDIES 856

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   989 ALISRKELLQKVSKLEEELAKVREEstkdslRESEKRELEEDSKNKDDpekygtsewrelevsLRLTISEKEVELEGIRR 1068
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNE------RASLEEALALLRSELEE---------------LSEELRELESKRSELRR 915

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564376925  1069 DLKEKAAAEEELQALVQRMTQDLQNktkqidlLQEEITENQATIQKFITGTMDAGDGDSAVKETSVSS 1136
Cdd:TIGR02168  916 ELEELREKLAQLELRLEGLEVRIDN-------LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2244-3028 9.02e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.16  E-value: 9.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2244 KAQTELQHQQKAYDKLQEENKELMSQLE------EAGQLYHDSKNELTKLESELksLKDQSTDLKNSLEKCREHENNLEG 2317
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELRELELAL--LVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2318 IIKQQEADIQNCKfncEQLETDLTASRELTTRLhDEINVKEQKIISLLSGKEEAIQVAIAELHQQHsKEIKELENLLSQE 2397
Cdd:TIGR02168  254 ELEELTAELQELE---EKLEELRLEVSELEEEI-EELQKELYALANEISRLEQQKQILRERLANLE-RQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2398 EEENLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSV---ILEKDEL 2474
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnneIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2475 IQDAAAENNKLKEEIRGLRGHMDdlNSENAKLDAELIQYRRDLNEVITIKDSQQRQLLEAQlQQNKELRNECVKLEGRLk 2554
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLE--EAELKELQAELEELEEELEELQEELERLEEALEELR-EELEEAEQALDAAEREL- 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2555 gseAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHeeGALAVYHAQLRVREEEVQKLTAALSS-----------SQK 2623
Cdd:TIGR02168  485 ---AQLQARLDSLERLQENLEGFSEGVKALLKNQSGLS--GILGVLSELISVDEGYEAAIEAALGGrlqavvvenlnAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2624 RTVDLQEE----LVCVQKEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAE----------------ERVAELARDLV 2683
Cdd:TIGR02168  560 KAIAFLKQnelgRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvlvvDDLDNALELAK 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2684 EMEQKLLTVTKENKDLTAQ-IQAFGK-----SMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGRQdlgresdvlsqa 2757
Cdd:TIGR02168  640 KLRPGYRIVTLDGDLVRPGgVITGGSaktnsSILERRREIEELEEKIEELEEKIAELEKALAELRKEL------------ 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2758 afplttsENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSFTKAMTSLQNERdhlwNELEKFRKSEEGKQRSAAPS 2837
Cdd:TIGR02168  708 -------EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL----TELEAEIEELEERLEEAEEE 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2838 AASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMNQEITELRplkAQLQESQDQTKALQMMKEELRQENLSWQHE 2917
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR---ERLESLERRIAATERRLEDLEEQIEELSED 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2918 LHQLRVEKNSWELHERRMKEQyLMAISDKDQQLGHLQNLLRELRSSSQTQILPTQYQRQAssgtsaaldgsqnlvyetdc 2997
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESE-LEALLNERASLEEALALLRSELEELSEELRELESKRSE-------------------- 912

                          810       820       830
                   ....*....|....*....|....*....|.
gi 564376925  2998 LRTQLNDSLKEIHQKELRIQQLNSKFSQLLE 3028
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQE 943
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 46-482 1.22e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 1.22e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   46 QKDVLDRLADAEKLVLELKDIISKQDAQLQQKDEALQEEKKGAESKIKKIKLHAKAKITSLNKQIEELKTQGGAASPPEV 125
Cdd:COG1196   332 LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEA 411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  126 QAEELSKHDKSSTEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEKEELIGALQT 205
Cdd:COG1196   412 LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  206 QLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQSDVETE----------VQQKLRVMQRKLEEHEEALL 275
Cdd:COG1196   492 RLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEaalaaalqniVVEDDEVAAAAIEYLKAAKA 571

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  276 GRAQVVDLLQKELTSAEQRNQDLSQQLQLLEAEHSTLRntmEAERQESKILMEKVELEMAERKEELYQLQGQLERAGQAQ 355
Cdd:COG1196   572 GRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR---EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLRE 648

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  356 AELEMQYGTLQQRHETEMEEKTACISLLQKNEQELQSACDALKEENSKLLQEQQEQAAKSAQALQQLEDELQQKSKEISQ 435
Cdd:COG1196   649 VTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEE 728

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 564376925  436 FVNKPNLEKHETSSQTSLPDVYNEGVQAVMEESVASLQKRVLELENE 482
Cdd:COG1196   729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 725-1465 1.32e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.79  E-value: 1.32e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   725 EEARSTLTAVCEERDQLLYRVKELDVLGELRAQVRELETSLAEAEKQRGL-DYESQRAQHNLLTEQIHSLSIEAKSKDVK 803
Cdd:TIGR02169  194 DEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIErQLASLEEELEKLTEEISELEKRLEEIEQL 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   804 IETLQRELD--------GVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMK----DISK---EMEELSQALSQKELEIA 868
Cdd:TIGR02169  274 LEELNKKIKdlgeeeqlRVKEKIGELEAEIASLERSIAEKERELEDAEERLAkleaEIDKllaEIEELEREIEEERKRRD 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   869 QMDQLLLEKKKDVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAES 948
Cdd:TIGR02169  354 KLTEEYAELKEELEDLRAELEEVDKEFAETR----DELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   949 SPKHGPHESSAQEPVCKDALQQELEWLRKESEQRKRKLQAALISRKELLQKV----SKLEEELAKVrEESTKDSLRESEK 1024
Cdd:TIGR02169  430 AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVekelSKLQRELAEA-EAQARASEERVRG 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1025 RELEEDSKNKDDPEKYGTSewRELEVSLRLTISEKEVELEG------IRRDLKEKAAAEEELQALVQRMTQDLQNKTKQI 1098
Cdd:TIGR02169  509 GRAVEEVLKASIQGVHGTV--AQLGSVGERYATAIEVAAGNrlnnvvVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDE 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1099 DLLQEEITENQA---------------TIQKFITG------TMDAG------------DGDSAVKETSVSSPPRAG-GGE 1144
Cdd:TIGR02169  587 RRDLSILSEDGVigfavdlvefdpkyePAFKYVFGdtlvveDIEAArrlmgkyrmvtlEGELFEKSGAMTGGSRAPrGGI 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1145 HWKPELEGKIVDLEKEKTQLQKKLQEALISRKAILKKAQEKEKHLKEELKEQKDAYRHLQEQFDGQSKENENIAARLRQL 1224
Cdd:TIGR02169  667 LFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1225 QAKEstdqqlpgtgQQEPTHGSEGLSLEGTEPASESDLHAAQPshpgETATLQATVSVAQIQdQLKEIEVEKEELELKIS 1304
Cdd:TIGR02169  747 SSLE----------QEIENVKSELKELEARIEELEEDLHKLEE----ALNDLEARLSHSRIP-EIQAELSKLEEEVSRIE 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1305 STTSELTKKSEEVLLLQEQINEqglEIQNLKAASHEAKAHTEQLKQELESSQLKIADLE-HLKTLQPELETLQKHVGQKE 1383
Cdd:TIGR02169  812 ARLREIEQKLNRLTLEKEYLEK---EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLK 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1384 EEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQakehEERLKQVQVEICELKKQPKELEEESKAKQQLQRKL 1463
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEAL----EEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVE 964


                   ..
gi 564376925  1464 QA 1465
Cdd:TIGR02169  965 EE 966
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1272-1758 1.79e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.79e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1272 ETATLQATVSVAQIQDQLKEIEVEKEELELKISSTTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQE 1351
Cdd:COG1196   266 EAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1352 LESSQLKIADLE-HLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHT---QLEMQAKE 1427
Cdd:COG1196   346 LEEAEEELEEAEaELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErleRLEEELEE 425

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1428 HEERLKQVQVEICELKkqpKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARD------AVEHLTKSLADV 1501
Cdd:COG1196   426 LEEALAELEEEEEEEE---EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEelaeaaARLLLLLEAEAD 502

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1502 ESQVSVQNQEKDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSC-----ESLKLALGGLTEDKEKLMKELESVRCSKI 1576
Cdd:COG1196   503 YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALqnivvEDDEVAAAAIEYLKAAKAGRATFLPLDKI 582

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1577 AESTEWQEKHKELQKEYEVLLQSYENVsnEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKM 1656
Cdd:COG1196   583 RARAALAAALARGAIGAAVDLVASDLR--EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG 660

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1657 RKFAKSKQQKILELEEENDRLRAEAQPVGGANESMEALLSSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNL 1736
Cdd:COG1196   661 SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740

                         490       500
                  ....*....|....*....|..
gi 564376925 1737 KLQVEAQELKQASLETTEKSDE 1758
Cdd:COG1196   741 LLEEEELLEEEALEELPEPPDL 762
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 675-1503 1.88e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.00  E-value: 1.88e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   675 QGELERLKTQVLELETSLHTAkethEKNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLyrvKELDVLGEL 754
Cdd:TIGR02168  266 EEKLEELRLEVSELEEEIEEL----QKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELE---SKLDELAEE 338

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   755 RAQVRELETSLAEaekqrglDYESQRAQHNLLTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQT 834
Cdd:TIGR02168  339 LAELEEKLEELKE-------ELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLER 411

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   835 KESEVLEGAERMKDISKEMEElsQALSQKELEIAQMDQLLLEKKKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF 914
Cdd:TIGR02168  412 LEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELERLEEALEELREELEEA----EQALDAAERELA 485

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   915 SLGVEIKTLKEQLSLLSRAEGAKKEQVedsgAESSPKHGPHessaqePVCKDALQQELEWlrkeseqrKRKLQAALISRk 994
Cdd:TIGR02168  486 QLQARLDSLERLQENLEGFSEGVKALL----KNQSGLSGIL------GVLSELISVDEGY--------EAAIEAALGGR- 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   995 elLQKVSKLEEELAKVREEStkdslresekreLEEDSKNKDDPEKYGTSEWRELEVSLRLTISEKEVELEGIRRDLKEKA 1074
Cdd:TIGR02168  547 --LQAVVVENLNAAKKAIAF------------LKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDP 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1075 AAEEELQALVQR--MTQDLQNKTKQIDLLQEEITenqatiqkFITgtmdaGDGDSAVKETSVSspPRAGGGEHWKPELEG 1152
Cdd:TIGR02168  613 KLRKALSYLLGGvlVVDDLDNALELAKKLRPGYR--------IVT-----LDGDLVRPGGVIT--GGSAKTNSSILERRR 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1153 KIVDLEKEKTQLQKKLQEALISRKAILKKAQEKEKH---LKEELKEQKDAYRHLQEQFDGQSKENENIAARLRQLQaKES 1229
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEEleqLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS-KEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1230 TDQQLPGTGQQEPTHGSEGLSLEGTEpasesdlhaaqpshpgETATLQATvsVAQIQDQLKEIEVEKEELELKISSTTSE 1309
Cdd:TIGR02168  757 TELEAEIEELEERLEEAEEELAEAEA----------------EIEELEAQ--IEQLKEELKALREALDELRAELTLLNEE 818

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1310 LTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIADLE-HLKTLQPELETLQKHVGQKEEEVSY 1388
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELEsELEALLNERASLEEALALLRSELEE 898

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1389 LVGQLGEKEQTLTTVQTEMEEQERLIKALHTQL---EMQAKEHEERL-KQVQVEICELKKQPKELEEESKAKQQLQRKLQ 1464
Cdd:TIGR02168  899 LSEELRELESKRSELRRELEELREKLAQLELRLeglEVRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARRRLKRLE 978

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 564376925  1465 AALIS----RKEALKENKSLQEQLSSARDAVEHLTKSLADVES 1503
Cdd:TIGR02168  979 NKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEE 1021
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 675-1228 5.05e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 5.05e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  675 QGELERLKTQVLELETSLhtakETHEKNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLlyrVKELDVLGEL 754
Cdd:COG1196   238 EAELEELEAELEELEAEL----EELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL---EQDIARLEER 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  755 RAQVRELETSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQT 834
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  835 KESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKF 914
Cdd:COG1196   391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE----EEEEALLELLA 466

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  915 SLGVEIKTLKEQLSLLSRAEGAKKEQVEdsgaesspkhgphessAQEPVCKDALQQELEWLRKESEQRKRKLQAALIsrk 994
Cdd:COG1196   467 ELLEEAALLEAALAELLEELAEAAARLL----------------LLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA--- 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  995 ELLQKVSKLEEELAKVREESTKDSLRESEKRELEEDSKNKDdpEKYGTSEWRELEVSLRLTISEKEVELEGIRRDLKEKA 1074
Cdd:COG1196   528 VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA--AKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1075 AAEEELQALVQRMTQDLQNKTKQIDLLQEEITENQATIQKFITGTMDAGDGDSAVKETSvssppragggehwkpELEGKI 1154
Cdd:COG1196   606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG---------------GSRREL 670

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564376925 1155 VDLEKEKTQLQKKLQEALISRKAILKKAQEKEKHLKEELKEQKDAYRHLQEQFDGQSKENENIAARLRQLQAKE 1228
Cdd:COG1196   671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEE 744
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 129-436 5.25e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 5.25e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   129 ELSKHDKSSTEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEKEELIGALQTQLS 208
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   209 QTQAEQAAQLSSMQQVVREKDARFETQVRLHED---ELLQLVTQSDVETEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQ 285
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQieqLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   286 KELTSAEQRNQDLSQQLQLLEAEHS---TLRNTMEAERQESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQY 362
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEeleELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRREL 917

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564376925   363 GTLQQRHETEMEEktacislLQKNEQELQSACDALKEENSKLLQEQQEQAAKSAQALQQLEDELQQKSKEISQF 436
Cdd:TIGR02168  918 EELREKLAQLELR-------LEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1320-1762 1.41e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.37  E-value: 1.41e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1320 LQEQINEQGLEIQNLKAASHEAKAHTE-QLKQELESSQLKIADLEHLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQ 1398
Cdd:pfam15921  417 LRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSER 496

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1399 TLTTVQTEMEEQERLIKALHTQLEMQAKEHEERLKQVQveicelkkqpkELEEESKAKQQLQRKLQAALISRKEALKENK 1478
Cdd:pfam15921  497 TVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ-----------HLKNEGDHLRNVQTECEALKLQMAEKDKVIE 565

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1479 SLQEQLSSARDAVEHLTKSLADVE---SQVSVQNQEKDALLGKLALLQEERDKLIVEMDKSLLENQslggsCESLKLALG 1555
Cdd:pfam15921  566 ILRQQIENMTQLVGQHGRTAGAMQvekAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE-----LEKVKLVNA 640

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1556 GltEDKEKLMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHvvesvrqekqEVYAKLRSAESDK 1635
Cdd:pfam15921  641 G--SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN----------KLKMQLKSAQSEL 708

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1636 REREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGANESMEALLSSNASLKEELERITLEYKTL 1715
Cdd:pfam15921  709 EQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 564376925  1716 SKEFEALMAEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKDV 1762
Cdd:pfam15921  789 AGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESV 835
PTZ00121 PTZ00121
MAEBL; Provisional
 1717-2505 2.14e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 2.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1717 KEFEALMAEKNTLSEETRN-LKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAV-VGKSQEQDSLSENAKLEDAEATLL 1794
Cdd:PTZ00121 1077 KDFDFDAKEDNRADEATEEaFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEeARKAEDARKAEEARKAEDAKRVEI 1156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1795 ANSAKPGVSETFSSHDDinnylqqlDQLKGRIAELEMEKQKDRELSQTLENEKNAlltqiSAKDSELKLLEEEVAKINml 1874
Cdd:PTZ00121 1157 ARKAEDARKAEEARKAE--------DAKKAEAARKAEEVRKAEELRKAEDARKAE-----AARKAEEERKAEEARKAE-- 1221

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1875 NQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEmqNLKRCVSELEEEKQQLVK 1954
Cdd:PTZ00121 1222 DAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKAD--ELKKAEEKKKADEAKKAE 1299

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1955 EKTKVEsEIRKEYMEKIQGAQ---KGPGSKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQK 2031
Cdd:PTZ00121 1300 EKKKAD-EAKKKAEEAKKADEakkKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2032 DLDATKGNlAQAVEHHKKAQAELSSFKILLDDTQ-SEAARVLADNLKLKKELQSNKESIKSQIKQKdedllRRLEQAEEK 2110
Cdd:PTZ00121 1379 KADAAKKK-AEEKKKADEAKKKAEEDKKKADELKkAAAAKKKADEAKKKAEEKKKADEAKKKAEEA-----KKADEAKKK 1452

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2111 HRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWEQ 2190
Cdd:PTZ00121 1453 AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEE 1532

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2191 RFGDAIQTKEEEVRLKEENCTALKDQLRQMTIHMEELKitvsRLEHDKEIWESKAQTELQHQQKAYD---KLQEENKELM 2267
Cdd:PTZ00121 1533 AKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAK----KAEEDKNMALRKAEEAKKAEEARIEevmKLYEEEKKMK 1608

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2268 SQLEEAGQLYHDSKNELTKLESELK---SLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNCKFNCEQLETDLTASR 2344
Cdd:PTZ00121 1609 AEEAKKAEEAKIKAEELKKAEEEKKkveQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEK 1688

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2345 ELTTRLHDEinvKEQKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALET 2424
Cdd:PTZ00121 1689 KAAEALKKE---AEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKE 1765

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2425 IKKESLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEER-HLSVILE---------------KDELIQDAAAENNKLKEE 2488
Cdd:PTZ00121 1766 EEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFdNFANIIEggkegnlvindskemEDSAIKEVADSKNMQLEE 1845

                         810
                  ....*....|....*..
gi 564376925 2489 IRGLRGHMDDLNSENAK 2505
Cdd:PTZ00121 1846 ADAFEKHKFNKNNENGE 1862
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2091-2900 2.53e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.55  E-value: 2.53e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2091 SQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKS 2170
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2171 MSSLQDDRDRVIDEAKKWEQRFGDAIQTKEEEVR----LKEENCTALKDQLRQMTIHMEELKITVSRLEHDKEiwesKAQ 2246
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE----DAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2247 TELQHQQKAYDKLQEENKELMSQLEEagqlyhdSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADI 2326
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELEREIEE-------ERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2327 QNCKFNCEQLETDLTASRELTTRLHDEINVKEQKIISLLSGKEEAIQVAIAElhqqhSKEIKELENLLSQEEEENLTLEE 2406
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDK-----ALEIKKQEWKLEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2407 ENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSS-------LQDDRDRIVSDYRQL---EERH-----------L 2465
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGgraveevLKASIQGVHGTVAQLgsvGERYataievaagnrL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2466 SVILEKDELIQDAAAEN--------------NKLKEEIR--------GLRGHMDDLNSENAKLDAELIQYRRDLNEVITI 2523
Cdd:TIGR02169  550 NNVVVEDDAVAKEAIELlkrrkagratflplNKMRDERRdlsilsedGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2524 kDSQQRQLLEAQLQQnkeLRNECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHEEgalavyhaq 2603
Cdd:TIGR02169  630 -EAARRLMGKYRMVT---LEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSE--------- 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2604 LRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKVSEIEDkLKRELKHLHHNAGIMRNETETAEERVAELARDLV 2683
Cdd:TIGR02169  697 LRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEE-LEEDLSSLEQEIENVKSELKELEARIEELEEDLH 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2684 EMEQKLLTVtkENKDLTAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQL-KGRQDLGRESDVL-SQAAFPL 2761
Cdd:TIGR02169  776 KLEEALNDL--EARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLeKEIQELQEQRIDLkEQIKSIE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2762 TTSENISSRLEKLNQQLTSKDEQLLHLSSELESshnqvqsftkamtsLQNERDHLWNELEKFRKSEEgkqrsaapsaaSS 2841
Cdd:TIGR02169  854 KEIENLNGKKEELEEELEELEAALRDLESRLGD--------------LKKERDELEAQLRELERKIE-----------EL 908

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925  2842 PAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMNQEITE---LRPLKAQLQESQDQTKAL 2900
Cdd:TIGR02169  909 EAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEelsLEDVQAELQRVEEEIRAL 970
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1667-2429 2.60e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.55  E-value: 2.60e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1667 ILELEEENDRLRAEAQPVGganESMEALLSSNASLKEELERI------TLEYKTLSK-----EFEALMAEKNTLSEETRN 1735
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVE---ENIERLDLIIDEKRQQLERLrrerekAERYQALLKekreyEGYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1736 LKLQVEAQELKQASL-----ETTEKSDEPKDVIEEVTEAVVGKSQEQdSLSENAKLEDAEAtllansakpgvsETFSSHD 1810
Cdd:TIGR02169  242 IERQLASLEEELEKLteeisELEKRLEEIEQLLEELNKKIKDLGEEE-QLRVKEKIGELEA------------EIASLER 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1811 DINNYLQQLDQLKGRIAELEMEKQKdrelsqtLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKE 1890
Cdd:TIGR02169  309 SIAEKERELEDAEERLAKLEAEIDK-------LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1891 TAEEEKDDLEE-----------------RLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLV 1953
Cdd:TIGR02169  382 ETRDELKDYREkleklkreinelkreldRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLA 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1954 KEKTKVESEIR--KEYMEKIQGAQKGPGSKIHAKELQ------------------------------ELLKEKQQEVKQL 2001
Cdd:TIGR02169  462 ADLSKYEQELYdlKEEYDRVEKELSKLQRELAEAEAQaraseervrggraveevlkasiqgvhgtvaQLGSVGERYATAI 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2002 Q------------------KDCIRYLGRISALEKTVKAL-EFVHTESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLD 2062
Cdd:TIGR02169  542 EvaagnrlnnvvveddavaKEAIELLKRRKAGRATFLPLnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFG 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2063 DT----QSEAARVLADNLK---LKKEL---------QSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALH 2126
Cdd:TIGR02169  622 DTlvveDIEAARRLMGKYRmvtLEGELfeksgamtgGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2127 REKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWEQRFGDaIQTKEEEVRLK 2206
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEE-LEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2207 EENCTA--LKDQLRQMTIHMEELKITVSRLE---HDKEIWESKAQTELQHQQKAYDKLQEENKELMSQLEEAGQLYHDSK 2281
Cdd:TIGR02169  781 LNDLEArlSHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLN 860

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2282 NELTKLESELKSLKDQSTDLKNSLEkcrehenNLEGIIKQQEADIQNCKFNCEQLETDLTASRELTTRLHDEINVKEQKI 2361
Cdd:TIGR02169  861 GKKEELEEELEELEAALRDLESRLG-------DLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564376925  2362 ISLLSGKEEAIQVAIAELH-QQHSKEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALETIKKES 2429
Cdd:TIGR02169  934 SEIEDPKGEDEEIPEEELSlEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEER 1002
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 674-1114 3.97e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.65  E-value: 3.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  674 HQGELERLKTQVLELETSLHTAKETHE----------KNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLY 743
Cdd:COG1196   251 LEAELEELEAELAELEAELEELRLELEeleleleeaqAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  744 RVKEL-DVLGELRAQVRELETSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQG 822
Cdd:COG1196   331 ELEELeEELEELEEELEEAEEELEEAEAEL----AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELE 406

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  823 TQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTIQEKDQQVTELSFSM 902
Cdd:COG1196   407 EAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  903 TEKMVQLN-----EEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAESSPKHGPHESSAQEPVCKDA--LQQELEWL 975
Cdd:COG1196   487 AEAAARLLllleaEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDevAAAAIEYL 566

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  976 RKESEQRKRKLQAALISRKELLQKVSKLEEELAKV-------REESTKDSLRESEKRELEEDSKNKDDPEKY-GTSEWRE 1047
Cdd:COG1196   567 KAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdlvasdlREADARYYVLGDTLLGRTLVAARLEAALRRaVTLAGRL 646

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925 1048 LEVSLRLTISEKEVELEGIRRDLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEEITENQATIQK 1114
Cdd:COG1196   647 REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 675-1208 4.14e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.65  E-value: 4.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  675 QGELERLKTQVLELETSLHTAKETHEKNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLYRVKELDvlgEL 754
Cdd:COG1196   266 EAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE---EL 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  755 RAQVRELETSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQT 834
Cdd:COG1196   343 EEELEEAEEELEEAEAEL----AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER 418

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  835 KESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTIQEKDQQVTELSFSMTEKMVQLN---- 910
Cdd:COG1196   419 LEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLllle 498

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  911 -EEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAESSPKHGPHESSAQEPVCKDA--LQQELEWLRKESEQRKRKLQ 987
Cdd:COG1196   499 aEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDevAAAAIEYLKAAKAGRATFLP 578

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  988 AALISRKELLQKVSKLEEELAKV-------REESTKDSLRESEKRELEEDSKNKDDPEKY-GTSEWRELEVSLRLTISEK 1059
Cdd:COG1196   579 LDKIRARAALAAALARGAIGAAVdlvasdlREADARYYVLGDTLLGRTLVAARLEAALRRaVTLAGRLREVTLEGEGGSA 658

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1060 EVELEGIRR--DLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEEITENQATIQKFITGTMDAGDGDSAVKETSVSSP 1137
Cdd:COG1196   659 GGSLTGGSRreLLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564376925 1138 PRAGGGEHWKPELEGKIVDLEKEKTQLQKKLQEALISRK--------AIlkkaqekekhlkEELKEQKDAYRHLQEQFD 1208
Cdd:COG1196   739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEalgpvnllAI------------EEYEELEERYDFLSEQRE 805
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1929-2492 5.80e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 5.80e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1929 EQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKgpgskihAKELQELLKEKQQEVKQLQKDCIRY 2008
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELE-------LEEAQAEEYELLAELARLEQDIARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2009 LGRISALEktvkalefvhtESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKES 2088
Cdd:COG1196   308 EERRRELE-----------ERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2089 IKSQIKQKDEDLLRRLEQAEEKhRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFT 2168
Cdd:COG1196   377 AEEELEELAEELLEALRAAAEL-AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2169 KSMSSLQDDRDRVIDEAKKWEQRFGDAIQTKEEEVRLKEenctALKDQLRQM--------TIHMEELKITVSRLEHDKEI 2240
Cdd:COG1196   456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL----LLLEAEADYegflegvkAALLLAGLRGLAGAVAVLIG 531

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2241 WESKAQTELQHQQKAYdkLQEENKELMSQLEEAGQlyHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIK 2320
Cdd:COG1196   532 VEAAYEAALEAALAAA--LQNIVVEDDEVAAAAIE--YLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASD 607

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2321 QQEADIQNCKFNCEQLETDLTASRELTTRLHDEINVKEQKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLSQEEEE 2400
Cdd:COG1196   608 LREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2401 NLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSVILEKDELIQDAAA 2480
Cdd:COG1196   688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767

                         570
                  ....*....|..
gi 564376925 2481 ENNKLKEEIRGL 2492
Cdd:COG1196   768 ELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 1956-2759 8.91e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 8.91e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1956 KTKVESEIRKEYMEKIQGAQKGPGSKIHAKELQELLKEKQQEVKQLQKdcIRYLGRISALEKTVKALEFVHTE-SQKDLD 2034
Cdd:PTZ00121 1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEE--ARKAEDARKAEEARKAEDAKRVEiARKAED 1162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2035 ATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQA-----EE 2109
Cdd:PTZ00121 1163 ARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAkkdaeEA 1242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2110 KHRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSldstlaqlaaftksmsslqddrdRVIDEAKKWE 2189
Cdd:PTZ00121 1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEK-----------------------KKADEAKKAE 1299

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2190 Q-RFGDAIQTKEEEVRLKEEnctaLKDQLRQMTIHMEELKITVSRLEHDKEIWESKAQTELQHQQKAYDKLQEENKELMS 2268
Cdd:PTZ00121 1300 EkKKADEAKKKAEEAKKADE----AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE 1375

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2269 QLEEAGQLyhDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEadiqnckfncEQLETDLTASRELTT 2348
Cdd:PTZ00121 1376 AKKKADAA--KKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAE----------EKKKADEAKKKAEEA 1443

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2349 RLHDEINVKEQKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLSQEEEENLTLEEENKRAVEK--TNQLTEALETIK 2426
Cdd:PTZ00121 1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKkkADEAKKAEEAKK 1523

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2427 KESL---EQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSVILEKDELIQDAAAENNKLKEEIRGLR-GHMDDLNSE 2502
Cdd:PTZ00121 1524 ADEAkkaEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARiEEVMKLYEE 1603

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2503 NAKLDAEliQYRRDLNEVITIKDSQQRQLLEAQLQQNKELRNECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIK 2582
Cdd:PTZ00121 1604 EKKMKAE--EAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK 1681

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2583 SFKEQ----LTALHEEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKVSE--IEDKLKRELKH 2656
Cdd:PTZ00121 1682 KAEEDekkaAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEakKDEEEKKKIAH 1761

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2657 LHHNAGIMRNETETAEERVAELARDlVEMEQKLLTVTKENKDLTAqiqafgkSMSSLQDSRDHATEELSDLKKKYDASLK 2736
Cdd:PTZ00121 1762 LKKEEEKKAEEIRKEKEAVIEEELD-EEDEKRRMEVDKKIKDIFD-------NFANIIEGGKEGNLVINDSKEMEDSAIK 1833

                         810       820
                  ....*....|....*....|...
gi 564376925 2737 ELAQLKGRQDlgRESDVLSQAAF 2759
Cdd:PTZ00121 1834 EVADSKNMQL--EEADAFEKHKF 1854
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1819-2130 8.92e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 8.92e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1819 LDQLKGRIAELEMEK---QKDRELSQTLEN-EKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEE 1894
Cdd:COG1196   195 LGELERQLEPLERQAekaERYRELKEELKElEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1895 EKDDLEERLMNQLAELNgsignyyqdvtDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGA 1974
Cdd:COG1196   275 ELEELELELEEAQAEEY-----------ELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELE 343

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1975 QKGPGSKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEfvhtESQKDLDATKGNLAQAVEHHKKAQAEL 2054
Cdd:COG1196   344 EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL----RAAAELAAQLEELEEAEEALLERLERL 419

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564376925 2055 SSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKA 2130
Cdd:COG1196   420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1401-1963 1.12e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 61.21  E-value: 1.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1401 TTVQTEMEEQERLIKALHTQLE-MQAKEHEERLKQVQVEICELKKQPKELEEEskaKQQLQRKLQAAlisrKEALKENKS 1479
Cdd:PRK02224  176 LGVERVLSDQRGSLDQLKAQIEeKEEKDLHERLNGLESELAELDEEIERYEEQ---REQARETRDEA----DEVLEEHEE 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1480 LQEQLSSARDAVEHLTKSLADVESqvsvqnqEKDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTE 1559
Cdd:PRK02224  249 RREELETLEAEIEDLRETIAETER-------EREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELED 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1560 DKEKLMKELESVRCSKIAESTEwqekhkelqkeyevllqsYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKRERE 1639
Cdd:PRK02224  322 RDEELRDRLEECRVAAQAHNEE------------------AESLREDADDLEERAEELREEAAELESELEEAREAVEDRR 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1640 KQLQdaeqemeemkekmrkfakskqqkilELEEENDRLRAEaqpVGGANESMEALLSSNASLKEELERITLEYKTLS--- 1716
Cdd:PRK02224  384 EEIE-------------------------ELEEEIEELRER---FGDAPVDLGNAEDFLEELREERDELREREAELEatl 435

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1717 KEFEALMAEKNTLSEETR--NLKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDaEATLL 1794
Cdd:PRK02224  436 RTARERVEEAEALLEAGKcpECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAED-RIERL 514

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1795 ANSAKPGVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEE------- 1867
Cdd:PRK02224  515 EERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERiesleri 594

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1868 ---VAKINMLNQQIQEELSRVTKLKETAEEEKDDLEERlMNQLAELNGSIGNyyQDVTDAQIKNEQLESEMQNLKRCVSE 1944
Cdd:PRK02224  595 rtlLAAIADAEDEIERLREKREALAELNDERRERLAEK-RERKRELEAEFDE--ARIEEAREDKERAEEYLEQVEEKLDE 671

                         570
                  ....*....|....*....
gi 564376925 1945 LEEEKQQLVKEKTKVESEI 1963
Cdd:PRK02224  672 LREERDDLQAEIGAVENEL 690
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 38-413 1.14e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.14e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   38 AMELNNSTQKDVLDRLADAEKLVLELKDIISKQDAQLQQKDEALQEEKKGAESkikkiklhAKAKITSLNKQIEELKTQG 117
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE--------AQAEEYELLAELARLEQDI 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  118 gaasppEVQAEELSKHDKSSTEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEKE 197
Cdd:COG1196   305 ------ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  198 ELIGALQTQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHE---DELLQLVTQSDVETEVQQKLRVMQRKLEEHEEAL 274
Cdd:COG1196   379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEeleELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  275 LGRAQVVDLLQKELTSAEQRNQDLSQQLQLLEAEHSTLRNTMEAERQESKILMEKVELEMAERKEELYQLQGQLERAGQA 354
Cdd:COG1196   459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564376925  355 QAELEMQyGTLQQRHETEMEEKTACISLLQKNEQELQSACDALKEENSKLLQEQQEQAA 413
Cdd:COG1196   539 ALEAALA-AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA 596
PTZ00121 PTZ00121
MAEBL; Provisional
 687-1228 1.16e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 1.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  687 ELETSLHTAKETHEKNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLYRVKELDVLGELRAQVRELEtsla 766
Cdd:PTZ00121 1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---- 1284

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  767 EAEKQRGLDyESQRAQHNLLTEQIHSLSIEAKskdvKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERM 846
Cdd:PTZ00121 1285 KAEEKKKAD-EAKKAEEKKKADEAKKKAEEAK----KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEA 1359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  847 KDiSKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTIQEKDQQVTELSFSMTEKmvQLNEEKFSLGVEIKT---L 923
Cdd:PTZ00121 1360 EA-AEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK--KKADEAKKKAEEKKKadeA 1436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  924 KEQLSLLSRAEGAKKEQVEDSGAESSPKHGPHESSAQEPVCKDALQQELEWLRKESEQRKRKLQAALISRKEllqkvSKL 1003
Cdd:PTZ00121 1437 KKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA-----KKK 1511

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1004 EEELAKVREESTKDSLRESEKRELEEDSKNKDdpEKYGTSEWRELEvslrltisekEVELEGIRRDLKEKAAAEEELQAL 1083
Cdd:PTZ00121 1512 ADEAKKAEEAKKADEAKKAEEAKKADEAKKAE--EKKKADELKKAE----------ELKKAEEKKKAEEAKKAEEDKNMA 1579

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1084 VQRMTQDLQNKTKQIDLLQEEITENQatiqkfitgTMDAGDGDSAVKETSVSSPPRAGGGEHWKPELEGKIVDLEKEKTQ 1163
Cdd:PTZ00121 1580 LRKAEEAKKAEEARIEEVMKLYEEEK---------KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAE 1650

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564376925 1164 LQKKLQEALISRKAILKKAQEKEKHLKEELKEQKDAYRHLQEQFDGQSKENENiAARLRQLQAKE 1228
Cdd:PTZ00121 1651 ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-AEELKKKEAEE 1714
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1158-1903 2.21e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.47  E-value: 2.21e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1158 EKEKTQLQKKLQEALISRKAILKKAQEKEKHLKEelkeqkdayrhLQEQFDGQSKENENIAARLRQLQAK---ESTDQQL 1234
Cdd:TIGR02169  222 EYEGYELLKEKEALERQKEAIERQLASLEEELEK-----------LTEEISELEKRLEEIEQLLEELNKKikdLGEEEQL 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1235 PGTGQQEPTHGsEGLSLEGTEPASESDLHAAQPShpgetatlqatvsVAQIQDQLKEIEVEKEELELKISSTTSELTKKS 1314
Cdd:TIGR02169  291 RVKEKIGELEA-EIASLERSIAEKERELEDAEER-------------LAKLEAEIDKLLAEIEELEREIEEERKRRDKLT 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1315 EEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIADlehlktLQPELETLQKHVGQKEEEVSYLVGQLG 1394
Cdd:TIGR02169  357 EEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE------LKRELDRLQEELQRLSEELADLNAAIA 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1395 EKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEheerLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEAL 1474
Cdd:TIGR02169  431 GIEAKINELEEEKEDKALEIKKQEWKLEQLAAD----LSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERV 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1475 KENKSLQEQLSSARDAVEHLTKSLADVESQ---------------VSVQNQE---------KDALLGKLALL------QE 1524
Cdd:TIGR02169  507 RGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaagnrlnnVVVEDDAvakeaiellKRRKAGRATFLplnkmrDE 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1525 ERDKLIVEMD------------------------------KSLLENQSLGGSCESLKLAlgGLTEDKEKLM-------KE 1567
Cdd:TIGR02169  587 RRDLSILSEDgvigfavdlvefdpkyepafkyvfgdtlvvEDIEAARRLMGKYRMVTLE--GELFEKSGAMtggsrapRG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1568 LESVRCSKIAESTEWQEKHKELQKEYEVLLQsyenvsnEAERIQHVVESVRQEKQEVYAKLRSAESDKrereKQLQDAEQ 1647
Cdd:TIGR02169  665 GILFSRSEPAELQRLRERLEGLKRELSSLQS-------ELRRIENRLDELSQELSDASRKIGEIEKEI----EQLEQEEE 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1648 EMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPvgganesMEALLssnASLKEELERITLEY-----KTLSKEFEAL 1722
Cdd:TIGR02169  734 KLKERLEELEEDLSSLEQEIENVKSELKELEARIEE-------LEEDL---HKLEEALNDLEARLshsriPEIQAELSKL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1723 MAEKNTLSEETRNLKLQVEAQELKQASLEttEKSDEPKDVIEEVTEAVVGKSQEQDSLseNAKLEDAEATL--LANSAKP 1800
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKLNRLTLEKEYLE--KEIQELQEQRIDLKEQIKSIEKEIENL--NGKKEELEEELeeLEAALRD 879

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1801 GVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVA------KINML 1874
Cdd:TIGR02169  880 LESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEeelsleDVQAE 959

                          810       820
                   ....*....|....*....|....*....
gi 564376925  1875 NQQIQEELSRVTKLKETAEEEKDDLEERL 1903
Cdd:TIGR02169  960 LQRVEEEIRALEPVNMLAIQEYEEVLKRL 988
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 678-1442 5.46e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 5.46e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   678 LERLKTQVLELETSLHTAKETHEKNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLYRVKELDV-LGELRA 756
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEkLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   757 QVRELETSLAEAEK--------QRGLDYESQRAQHNL--LTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIR 826
Cdd:TIGR02168  275 EVSELEEEIEELQKelyalaneISRLEQQKQILRERLanLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   827 SLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTIQEKDQQVTELSFSMTEKM 906
Cdd:TIGR02168  355 SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   907 VQLNEEKFS-LGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAESSPKHGPHESSAQEPVCKDALQQELE-------WLRKE 978
Cdd:TIGR02168  435 LKELQAELEeLEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEgfsegvkALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   979 SEQRKRK-------------------------LQAALISRKEL-LQKVSKLEEELAKVREESTKDSLRESEKRELEEDSK 1032
Cdd:TIGR02168  515 QSGLSGIlgvlselisvdegyeaaieaalggrLQAVVVENLNAaKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1033 NKDDPEKYGTSEWRELEVSLRLTIS------------------------------------------------------E 1058
Cdd:TIGR02168  595 KNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldnalelakklrpgyrivtldgdlvrpggvitggsaktnssilE 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1059 KEVELEGIRRDLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEEITENQATIqkfitgtmdagdgdsavketsvsspp 1138
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI-------------------------- 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1139 raGGGEHWKPELEGKIVDLEKEKTQLQKKLQEALISRKAILKKAQEKEKHLKEELKEQKDayrhLQEQFDGQSKENENIA 1218
Cdd:TIGR02168  729 --SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE----LEAQIEQLKEELKALR 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1219 ARLRQLQAKESTDQQlpgtgqqepthgseglslegtepasesdlhaaqpshpgetATLQATVSVAQIQDQLKEIEVEKEE 1298
Cdd:TIGR02168  803 EALDELRAELTLLNE----------------------------------------EAANLRERLESLERRIAATERRLED 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1299 LELKISSTTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIADLE-HLKTLQPELETLQK 1377
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELEsKRSELRRELEELRE 922

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564376925  1378 HVGQKEEEVSYLVGQLGEKEQTLtTVQTEMEEQErlIKALHTQLEMQAKEHEERLKQVQVEICEL 1442
Cdd:TIGR02168  923 KLAQLELRLEGLEVRIDNLQERL-SEEYSLTLEE--AEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 150-439 9.52e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.14  E-value: 9.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   150 ELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEKEELIGALQTQLSQTQAEQ---AAQLSSMQQVVR 226
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVeqlEERIAQLSKELT 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   227 EKDARFETQVRLHEDELLQLVTQSDVETEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQLQLLE 306
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   307 AEHSTLRNTMEAERQEskilMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQygtlQQRHETEMEEKTACISLLQKN 386
Cdd:TIGR02168  838 RRLEDLEEQIEELSED----IESLAAEIEELEELIEELESELEALLNERASLEEA----LALLRSELEELSEELRELESK 909

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 564376925   387 EQELQSACDALKEENSKLLQEQQEQAAKSAQALQQLEDELQQKSKEISQFVNK 439
Cdd:TIGR02168  910 RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENK 962
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1805-2023 9.58e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.08  E-value: 9.58e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1805 TFSSHDDINNYLQQLDQLKGRIAELEMEKQKdrelsqtLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSR 1884
Cdd:COG4942    15 AAAQADAAAEAEAELEQLQQEIAELEKELAA-------LKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1885 VTKLKETAEEEKDDLEERLMNQLAELNGSIGNYY-------QDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKT 1957
Cdd:COG4942    88 LEKEIAELRAELEAQKEELAELLRALYRLGRQPPlalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA 167

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925 1958 KVESEI-RKEYMEKIQGAQKgpgskihaKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALE 2023
Cdd:COG4942   168 ELEAERaELEALLAELEEER--------AALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 66-424 1.04e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.14  E-value: 1.04e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925    66 IISKQDAQLQQKDEALQEEKKGAESKIKKIKlhakAKITSLNKQIEELKTQGGAAsppevqAEELSKHDKSSTEEEMEVE 145
Cdd:TIGR02168  660 VITGGSAKTNSSILERRREIEELEEKIEELE----EKIAELEKALAELRKELEEL------EEELEQLRKELEELSRQIS 729

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   146 KIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEKEELIGALQTQLSQTQAEQAA---QLSSMQ 222
Cdd:TIGR02168  730 ALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAlreALDELR 809

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   223 QVVREKDARFETQVRLHEDELLQLVTQSDVETEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQL 302
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   303 QLLEAEHSTLR---NTMEAERQESKILMEKVELEMAERKEELYQLQGQLEragQAQAELEMQYGTLQQRHETEMEEKTAC 379
Cdd:TIGR02168  890 ALLRSELEELSeelRELESKRSELRRELEELREKLAQLELRLEGLEVRID---NLQERLSEEYSLTLEEAEALENKIEDD 966

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 564376925   380 ISLLQKNEQELQSACDALKEENSKLLQEQQEQAAKSAQALQQLED 424
Cdd:TIGR02168  967 EEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKED 1011
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 47-582 1.80e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.25  E-value: 1.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   47 KDVLDRLADAEKLVLELKDIISKQDAQLQQKDEALQEEKKGAESKIKKIKlHAKAKITSLNKQIEELKTQGgaasppEVQ 126
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE-EAQAEEYELLAELARLEQDI------ARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  127 AEELSKHDKSSTEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEKEELIGALQTQ 206
Cdd:COG1196   308 EERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  207 LSQTQAEQAAQLSSMQQVVREKDARFETQVRLHE---DELLQLVTQSDVETEVQQKLRVMQRKLEEHEEALLGRAQVVDL 283
Cdd:COG1196   388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEeleELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  284 LQKELTSAEQRNQDLSQQLQLLEAEHSTLRNTMEAERQESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQyG 363
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA-A 546

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  364 TLQQRHETEMEEKTACISLLQKNEQELQSACDALKEENSKLLQEQQEQAAkSAQALQQLEDELQQKSKEISQFVN----- 438
Cdd:COG1196   547 ALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA-IGAAVDLVASDLREADARYYVLGDtllgr 625

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  439 ------KPNLEKHETSSQTSLPDVYNEGVQAVMEESVASLQKRVLELENEKGALLLSSLELEELRAENEKLCSRITLLEA 512
Cdd:COG1196   626 tlvaarLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEE 705

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  513 QNRAGEADGMVCEVSTAGIALLNRSDSSTEESGQDVLENTFSQKHKELSVLLVEM------------------------- 567
Cdd:COG1196   706 ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPdleelerelerlereiealgpvnll 785

                         570       580
                  ....*....|....*....|
gi 564376925  568 -----KEAQEEIAFLKSQLQ 582
Cdd:COG1196   786 aieeyEELEERYDFLSEQRE 805
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 47-898 1.81e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 1.81e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925    47 KDVLDRLADAEKLVLELKDIISKQDAQLQ---------QKDEALQEEKKGAESKIKKIKLH-AKAKITSLNKQIEELKTQ 116
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQLKslerqaekaERYKELKAELRELELALLVLRLEeLREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   117 GGAASPPEVQAEE-LSKHDKSSTEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQE 195
Cdd:TIGR02168  255 LEELTAELQELEEkLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   196 KEELIGALQTQLSQTQAEQAAQLSSMqqvvrekdarfetqvrlhedellqlvtqsdveTEVQQKLRVMQRKLEEHEEALL 275
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESLEAEL--------------------------------EELEAELEELESRLEELEEQLE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   276 GRAQVVDLLQKELTSAEQRNQDLSQQLQLLEAEHSTLRNTMEAERQE-SKILMEKVELEMAERKEELYQLQGQLERAGQA 354
Cdd:TIGR02168  383 TLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERLEEA 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   355 QAELEMQYGTLQQR---HETEMEEKTACISLLQKNEQELQSACDALKEENSKLLQ--------------EQQEQAAKSA- 416
Cdd:TIGR02168  463 LEELREELEEAEQAldaAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgilgvlselisvDEGYEAAIEAa 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   417 --QALQQLEDELQQKSKEISQFVNKPNLEKHETSSQTSLPDVYNEGVQAVMEESVaslqkrvlelENEKGALLLSSLELE 494
Cdd:TIGR02168  543 lgGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNI----------EGFLGVAKDLVKFDP 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   495 ELRAENEKLCSRI----TLLEAQNRAGEADGMVCEVSTAGiALLNRSDSSTEESGQDVLeNTFSQKhKELSVLLVEMKEA 570
Cdd:TIGR02168  613 KLRKALSYLLGGVlvvdDLDNALELAKKLRPGYRIVTLDG-DLVRPGGVITGGSAKTNS-SILERR-REIEELEEKIEEL 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   571 QEEIAFLKSQLQGKRpegdyevldrKEVQMMESEGlpsVTARDVLCAPRDKNSVPAVEGEQAGMRDQHGTLEAGPLNDTG 650
Cdd:TIGR02168  690 EEKIAELEKALAELR----------KELEELEEEL---EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   651 MELNSPQPDGVDKSLSAphvclchQGELERLKTQVLELETSLHTAKETHEKNLSEKAKEISSLTQLTKEFKESAEEARST 730
Cdd:TIGR02168  757 TELEAEIEELEERLEEA-------EEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESL 829

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   731 LTAVCEERDQLLYRVKELDVLGE----LRAQVRELETSLAEAEKQRGL---DYESQRAQHNLLTEQIHSLSIEAKSKDVK 803
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEdiesLAAEIEELEELIEELESELEAllnERASLEEALALLRSELEELSEELRELESK 909

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   804 IETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEG--------AERMKDISKEMEELSQALSQKELEIAQMD---- 871
Cdd:TIGR02168  910 RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltleeaEALENKIEDDEEEARRRLKRLENKIKELGpvnl 989

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....
gi 564376925   872 -------------QLLLEKKKDV----ETLQQTIQEKDQQVTEL 898
Cdd:TIGR02168  990 aaieeyeelkeryDFLTAQKEDLteakETLEEAIEEIDREARER 1033
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2319-3068 1.90e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.90e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2319 IKQQEADIQNCKFNCEQLETDLTASRELTTRLHDEINVKEqKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLS--- 2395
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREYEGYELLKEKEALERQKEAIERQLAsle 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2396 -QEEEENLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEErhlsvilEKDEL 2474
Cdd:TIGR02169  251 eELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE-------DAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2475 IQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVitikdsqqRQLLEAQLQQNKELRNECVKLEGRLK 2554
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDL--------RAELEEVDKEFAETRDELKDYREKLE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2555 GSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHE-----EGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQ 2629
Cdd:TIGR02169  396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAkinelEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2630 EELVCVQKEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAEER--VAELARDLVEMEQKLLTvtkenkdltAQIQAFG 2707
Cdd:TIGR02169  476 EEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIqgVHGTVAQLGSVGERYAT---------AIEVAAG 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2708 KSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGRQDLGRESDVLSQAAF------------------------PLTT 2763
Cdd:TIGR02169  547 NRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVigfavdlvefdpkyepafkyvfgdTLVV 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2764 SENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSFTKAMTSLQNERDHLWNELEKFRKSEEGKQrsaaPSAASSPA 2843
Cdd:TIGR02169  627 EDIEAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ----SELRRIEN 702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2844 EVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMNQEITELRplkAQLQESQDQTKALQMMKEELRQENLSWQHELHQLRV 2923
Cdd:TIGR02169  703 RLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE---EDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2924 EKNSWELHERRMKEQYLMAISDK-DQQLGHLQNLLRELRSSSQTQILPTQYQRQASsgtsaaldgsQNLVYETDCLRTQL 3002
Cdd:TIGR02169  780 ALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI----------QELQEQRIDLKEQI 849

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564376925  3003 NDSLKEIHQKELRIQQLNSKFSQLLEEKNILSTQLRDANQSLRDSQHHYSNLFNHCAILERQVQQL 3068
Cdd:TIGR02169  850 KSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1372-1903 2.15e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.97  E-value: 2.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1372 LETLQKHVGQKEEevSYLVGQLGEKEQTLTTVQTEM---EEQERLIKALHTQLEMQAKEHEERLKqvqvEICELKKQPKE 1448
Cdd:PRK02224  189 LDQLKAQIEEKEE--KDLHERLNGLESELAELDEEIeryEEQREQARETRDEADEVLEEHEERRE----ELETLEAEIED 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1449 LEEeskakqqlqrklqaaliSRKEALKENKSLQEQLSSARDAVEHLTKSLADVESQVSVQNQEKDALLGKLALLQEERDK 1528
Cdd:PRK02224  263 LRE-----------------TIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEE 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1529 LIVEMDKSLLENQSLGGSCESLK---LALGGLTEDKEKLMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYENVSN 1605
Cdd:PRK02224  326 LRDRLEECRVAAQAHNEEAESLRedaDDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPV 405

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1606 EAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEE----------MKEKMRKFAKSKQQKILELEEEND 1675
Cdd:PRK02224  406 DLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELEAELE 485

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1676 RLRAEAQPVGGANESMEALLSSNASLKEELERitleyktlSKEFEALMAEKNTLSEETRNL--KLQVEAQELKQASLETT 1753
Cdd:PRK02224  486 DLEEEVEEVEERLERAEDLVEAEDRIERLEER--------REDLEELIAERRETIEEKRERaeELRERAAELEAEAEEKR 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1754 EKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKPG-----VSETFSSHDDINN-YLQQLDQLKGRIA 1827
Cdd:PRK02224  558 EAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEdeierLREKREALAELNDeRRERLAEKRERKR 637

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564376925 1828 ELEMEKQKDRelSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKetaeEEKDDLEERL 1903
Cdd:PRK02224  638 ELEAEFDEAR--IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELR----ERREALENRV 707
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1283-1964 2.39e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 56.98  E-value: 2.39e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1283 AQIQDQLKEIEVEKEELELKISSTTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELE--------- 1353
Cdd:TIGR00606  415 ADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERelskaekns 494

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1354 SSQLKIADLEHLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEqTLTTVQTEMEEQERLIKALHTQLEMQAKEHEERLK 1433
Cdd:TIGR00606  495 LTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQME-MLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKK 573

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1434 QVQVEICELKKQPKELEEESKakqQLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSlADVESQVSVQNQEKD 1513
Cdd:TIGR00606  574 QLEDWLHSKSKEINQTRDRLA---KLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEIE 649

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1514 ALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTEdkekLMKELESVRCSKIAESTEWQEKHKELQKEY 1593
Cdd:TIGR00606  650 KSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQE----FISDLQSKLRLAPDKLKSTESELKKKEKRR 725

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1594 EVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQ--DAEQEMEEMKEKMRKFAKSKQQKILELE 1671
Cdd:TIGR00606  726 DEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGtiMPEEESAKVCLTDVTIMERFQMELKDVE 805

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1672 EENDRLRAEAQPVGGaNESMEALLSSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLK-----LQVEAQELK 1746
Cdd:TIGR00606  806 RKIAQQAAKLQGSDL-DRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKseklqIGTNLQRRQ 884

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1747 QASLETTEKSDEPKDVIEEVTEAvvgksQEQDSLSENAKLEDAEATLLANSAKPgvSETFSSHDDINNYLQQLDQLKGRI 1826
Cdd:TIGR00606  885 QFEEQLVELSTEVQSLIREIKDA-----KEQDSPLETFLEKDQQEKEELISSKE--TSNKKAQDKVNDIKEKVKNIHGYM 957

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1827 AELEMEKQ--KDRELSQTlENEKNALLTQISAKDSELKLLEEEV--AKINMLNQQIQEELSRVTKLKETAEEEKDDLEER 1902
Cdd:TIGR00606  958 KDIENKIQdgKDDYLKQK-ETELNTVNAQLEECEKHQEKINEDMrlMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEE 1036

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925  1903 LMNQLAELNgsignyYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIR 1964
Cdd:TIGR00606 1037 LKQHLKEMG------QMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELR 1092
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1812-2393 2.55e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 56.61  E-value: 2.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1812 INNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNalltQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKET 1891
Cdd:PRK03918  157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEE----LIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1892 AEEEKDDLEErLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQqlVKEKTKVESEIRKEYMEKI 1971
Cdd:PRK03918  233 LEELKEEIEE-LEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKE--KAEEYIKLSEFYEEYLDEL 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1972 QGAQKGPGS-KIHAKELQELLKE---KQQEVKQLQKDCIRYLGRISALEKTVKALEFVHtESQKDLDATKGNLAQavEHH 2047
Cdd:PRK03918  310 REIEKRLSRlEEEINGIEERIKEleeKEERLEELKKKLKELEKRLEELEERHELYEEAK-AKKEELERLKKRLTG--LTP 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2048 KKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHR 2127
Cdd:PRK03918  387 EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEK 466

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2128 EKAHVEDTLAEIQVSLTRKDKDMKELQQ--SLDSTLAQLAAFTKSMSSLqddrdrvidEAKKWEQRFGDAIQTKEEEVRL 2205
Cdd:PRK03918  467 ELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKELEEKLKKY---------NLEELEKKAEEYEKLKEKLIKL 537

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2206 KEENCTALKDQLRqmtihMEELKITVSRLEHDKEIWESKAQTELQHQQKAYDKLQEENKELMSQLEEAGQLYHDSKNELT 2285
Cdd:PRK03918  538 KGEIKSLKKELEK-----LEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEK 612

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2286 KLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEAdiQNCKFNCEQLETdltaSRELTTRLHDEINVKEQKIISLL 2365
Cdd:PRK03918  613 ELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE--LEKKYSEEEYEE----LREEYLELSRELAGLRAELEELE 686

                         570       580       590
                  ....*....|....*....|....*....|
gi 564376925 2366 SGKEEAIQVA--IAELHQQHSKEIKELENL 2393
Cdd:PRK03918  687 KRREEIKKTLekLKEELEEREKAKKELEKL 716
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
675-1103 2.64e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.59  E-value: 2.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  675 QGELERLKTQVLELE-TSLHTAKETHEKNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQllyrvkeldvLGE 753
Cdd:PRK02224  186 RGSLDQLKAQIEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE----------LET 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  754 LRAQVRELETSLAEAEKQR---GLDYESQRAQHNLLTEQIHSL-------SIEAKSKDVKIETLQRELDGVQLQFSEQGT 823
Cdd:PRK02224  256 LEAEIEDLRETIAETEREReelAEEVRDLRERLEELEEERDDLlaeagldDADAEAVEARREELEDRDEELRDRLEECRV 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  824 QIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTIQEKDQQ---VTELSF 900
Cdd:PRK02224  336 AAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDlgnAEDFLE 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  901 SMTEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKK-----EQVEDSgaesspkhgPHESSAQEP-VCKDALQQELEW 974
Cdd:PRK02224  416 ELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEGS---------PHVETIEEDrERVEELEAELED 486

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  975 LRKESEQRKRKLQAALISRK------ELLQKVSKLEEELAKVREESTKDSLRESEKRELEEDSKNKDDpekygtsEWREL 1048
Cdd:PRK02224  487 LEEEVEEVEERLERAEDLVEaedrieRLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAE-------EKREA 559

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 564376925 1049 EVSLRLTISEKEVELEGIRRDLKEKAAAEEELQALVQRMTqDLQNKTKQIDLLQE 1103
Cdd:PRK02224  560 AAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLA-AIADAEDEIERLRE 613
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2080-2741 3.09e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.57  E-value: 3.09e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2080 KELQSNKESIKSQIKQKdEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDS 2159
Cdd:TIGR04523   36 KQLEKKLKTIKNELKNK-EKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKN 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2160 TLAQLAAFTKSMSSLQddrdRVIDEAKKWEQRFGDAIQTKEEEVRLKEENCTALKDQLRQMTIHMEELKITVSRLEHD-- 2237
Cdd:TIGR04523  115 DKEQKNKLEVELNKLE----KQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNid 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2238 --------KEIWESKAQTELQHQ---QKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLE 2306
Cdd:TIGR04523  191 kiknkllkLELLLSNLKKKIQKNkslESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLS 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2307 KCREHENNLEGIIKQQEADIQNCKFNCEQLETDltASRELTTRLHDEINVKEQKIISLLSGKEEAIQvAIAELHQQHSKE 2386
Cdd:TIGR04523  271 EKQKELEQNNKKIKELEKQLNQLKSEISDLNNQ--KEQDWNKELKSELKNQEKKLEEIQNQISQNNK-IISQLNEQISQL 347

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2387 IKELENLLSQEeeenltleeenkraVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDRIvSDYRQLEErhls 2466
Cdd:TIGR04523  348 KKELTNSESEN--------------SEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKI-QNQEKLNQ---- 408

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2467 vilEKDELIQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVITIKDSQQRQLleaqlqqnKELRNEC 2546
Cdd:TIGR04523  409 ---QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQL--------KVLSRSI 477

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2547 VKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALheegalavyhaqlrvrEEEVQKLTAALSSSQKRTV 2626
Cdd:TIGR04523  478 NKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSL----------------KEKIEKLESEKKEKESKIS 541

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2627 DLQEELVCVQKEASKKVSEIE-DKLKRELKHLHHNAGIMRNETETAEERVAELArdlvemeqklltvtKENKDLTAQIQA 2705
Cdd:TIGR04523  542 DLEDELNKDDFELKKENLEKEiDEKNKEIEELKQTQKSLKKKQEEKQELIDQKE--------------KEKKDLIKEIEE 607

                          650       660       670
                   ....*....|....*....|....*....|....*....
gi 564376925  2706 FGKSMSSLQDSRDHATEE---LSDLKKKYDASLKELAQL 2741
Cdd:TIGR04523  608 KEKKISSLEKELEKAKKEnekLSSIIKNIKSKKNKLKQE 646
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1833-2454 3.15e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.18  E-value: 3.15e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1833 KQKDRELsQTLENEKNALLTQISAKDSELKLLEeevAKINMLNQQIQEELSRVTKL----KETAEEEKDDLEE--RLMNQ 1906
Cdd:TIGR04523   50 KNKEKEL-KNLDKNLNKDEEKINNSNNKIKILE---QQIKDLNDKLKKNKDKINKLnsdlSKINSEIKNDKEQknKLEVE 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1907 LAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIrkeymEKIQGAQKGPGSKIHAKE 1986
Cdd:TIGR04523  126 LNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEK-----LNIQKNIDKIKNKLLKLE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1987 LQ-ELLKEKQQEVKQLQKDcirylgrISALEKTVKALEFVHTESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLDDTQ 2065
Cdd:TIGR04523  201 LLlSNLKKKIQKNKSLESQ-------ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQ 273

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2066 SEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLD--------------ALHREKAH 2131
Cdd:TIGR04523  274 KELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISqnnkiisqlneqisQLKKELTN 353

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2132 VEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQddrdRVIDEAKKWEQRFGDAIQTKEEEVRLKEENCT 2211
Cdd:TIGR04523  354 SESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLE----SKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2212 ALK-------DQLRQMTIHMEELKITVSRLEHDKEIWESKAQTELQHQQKAYDKLQEENKELMSQLEEAGQLyhdsKNEL 2284
Cdd:TIGR04523  430 RLKetiiknnSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKL----NEEK 505

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2285 TKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNCKFNC--EQLETDLTASRELTTRLHDEIN--VKEQK 2360
Cdd:TIGR04523  506 KELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELkkENLEKEIDEKNKEIEELKQTQKslKKKQE 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2361 IISLLSGKEEAIQVAIAELHQQHSKEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFV 2440
Cdd:TIGR04523  586 EKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEII 665

                          650
                   ....*....|....
gi 564376925  2441 KSMSSLQDDRDRIV 2454
Cdd:TIGR04523  666 KKIKESKTKIDDII 679
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1356-1748 3.46e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.31  E-value: 3.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1356 QLKIADLEHLKTLQPELETLQKHVG---QKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHE--- 1429
Cdd:COG4717    64 RKPELNLKELKELEEELKEAEEKEEeyaELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAElae 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1430 --ERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKEN-KSLQEQLSSARDAVEHLTKSLADVESQVS 1506
Cdd:COG4717   144 lpERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELE 223

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1507 VQNQEKDALLGKLALLQEERD----KLIVEMDKSLLENQSLGGSCESLKLALGGL------------------TEDKEKL 1564
Cdd:COG4717   224 ELEEELEQLENELEAAALEERlkeaRLLLLIAAALLALLGLGGSLLSLILTIAGVlflvlgllallflllareKASLGKE 303

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1565 MKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEvyaklRSAESDKREREKQLQD 1644
Cdd:COG4717   304 AEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE-----LQLEELEQEIAALLAE 378

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1645 AEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAqpvGGANESMEALlsSNASLKEELERITLEYKTLSKEFEALMA 1724
Cdd:COG4717   379 AGVEDEEELRAALEQAEEYQELKEELEELEEQLEELL---GELEELLEAL--DEEELEEELEELEEELEELEEELEELRE 453

                         410       420
                  ....*....|....*....|....
gi 564376925 1725 EKNTLSEETRNLKLQVEAQELKQA 1748
Cdd:COG4717   454 ELAELEAELEQLEEDGELAELLQE 477
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1558-2093 3.58e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 56.23  E-value: 3.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1558 TEDKEKLMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIqhvvESVRQEKQEVYAKLRSAESDKRE 1637
Cdd:PRK03918  188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI----EELEKELESLEGSKRKLEEKIRE 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1638 REKQLQDAEQEMEEMKEKM----------------RKFAKSKQQKILELEEENDRLRAEAQPVG---GANESMEALLSSN 1698
Cdd:PRK03918  264 LEERIEELKKEIEELEEKVkelkelkekaeeyiklSEFYEEYLDELREIEKRLSRLEEEINGIEeriKELEEKEERLEEL 343

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1699 ASLKEELERITLEYKTLSKEFE---ALMAEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAVVGKSQ 1775
Cdd:PRK03918  344 KKKLKELEKRLEELEERHELYEeakAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKE 423

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1776 EQDSLSENAKL------------EDAEATLLANSAKpgvsETFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELS--- 1840
Cdd:PRK03918  424 LKKAIEELKKAkgkcpvcgreltEEHRKELLEEYTA----ELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIklk 499

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1841 ---QTLENEKNAL----LTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLK---ETAEEEKDDLEERLMNQLAEL 1910
Cdd:PRK03918  500 elaEQLKELEEKLkkynLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKkklAELEKKLDELEEELAELLKEL 579

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1911 NGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVEsEIRKEYMEKIQGAQKgpgskiHAKELQEL 1990
Cdd:PRK03918  580 EELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELD-KAFEELAETEKRLEE------LRKELEEL 652

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1991 LKE-KQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDatkgNLAQAVEHHKKAQAELSSFKILLDDTQSEAA 2069
Cdd:PRK03918  653 EKKySEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLE----KLKEELEEREKAKKELEKLEKALERVEELRE 728

                         570       580
                  ....*....|....*....|....
gi 564376925 2070 RVLADNLKLKKELQSNKESIKSQI 2093
Cdd:PRK03918  729 KVKKYKALLKERALSKVGEIASEI 752
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2281-2884 3.60e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.18  E-value: 3.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2281 KNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNCKFNCEQLETDLTASRELTTRLHDEINVKEQK 2360
Cdd:TIGR04523   46 KNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVE 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2361 IISLLSGKEEaiqvaIAELHQQHSKEIKELENLLsqeeeenltleeenkravektNQLTEALETIKKESLEQKAQLDSFV 2440
Cdd:TIGR04523  126 LNKLEKQKKE-----NKKNIDKFLTEIKKKEKEL---------------------EKLNNKYNDLKKQKEELENELNLLE 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2441 KSMSSLQDDRDRIVSDYRQLEERhLSVILEKDELIQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEV 2520
Cdd:TIGR04523  180 KEKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQL 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2521 ITIKDSQQRQLLEAQlqqnkelrNECVKLEGRLKGSEAEKQSLQMSLDAL-QEENQGLSKEIKSfkeqltalheegalav 2599
Cdd:TIGR04523  259 KDEQNKIKKQLSEKQ--------KELEQNNKKIKELEKQLNQLKSEISDLnNQKEQDWNKELKS---------------- 314

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2600 yhaQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKVSEiEDKLKRELKHLHHNAGIMRNETETAEERVAELA 2679
Cdd:TIGR04523  315 ---ELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESE-NSEKQRELEEKQNEIEKLKKENQSYKQEIKNLE 390

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2680 RDLVEMEQKLLTVTKENKDLTAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGR-QDLGRESDVLSQAA 2758
Cdd:TIGR04523  391 SQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIiKNLDNTRESLETQL 470

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2759 FPLTTS-ENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSFTKAMTSLQNERDHLWNELEKFR-----KSEEGKQR 2832
Cdd:TIGR04523  471 KVLSRSiNKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKEskisdLEDELNKD 550

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 564376925  2833 SAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMNQEITELR 2884
Cdd:TIGR04523  551 DFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLI 602
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1400-2003 5.46e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.84  E-value: 5.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1400 LTTVQTEMEEQERLIKAlHTQLEMQAKEHEERLKQVQVEICELKKQPKELEEE-SKAKQQLQR------KLQAALISRKE 1472
Cdd:PRK03918  171 IKEIKRRIERLEKFIKR-TENIEELIKEKEKELEEVLREINEISSELPELREElEKLEKEVKEleelkeEIEELEKELES 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1473 ALKENKSLQEQLSSARDAVEHLTKSLADVESQVsvqnqekdALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKL 1552
Cdd:PRK03918  250 LEGSKRKLEEKIRELEERIEELKKEIEELEEKV--------KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEE 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1553 ALGGLtedkEKLMKELEsvrcSKIAESTEWQEKHKELQKEYEVlLQSYENVSNEAERIQHVVESVRQEK-----QEVYAK 1627
Cdd:PRK03918  322 EINGI----EERIKELE----EKEERLEELKKKLKELEKRLEE-LEERHELYEEAKAKKEELERLKKRLtgltpEKLEKE 392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1628 LRSAESDKREREKQLQDAEQEMEEMKEKmrkfAKSKQQKILELEEENDRLraeaqPVGGANESMEALLSSNASLKEELER 1707
Cdd:PRK03918  393 LEELEKAKEEIEEEISKITARIGELKKE----IKELKKAIEELKKAKGKC-----PVCGRELTEEHRKELLEEYTAELKR 463

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1708 ITLEYKTLSKEFEALMAEK----NTLSEETRNLKLQVEAQELKQASLETT----EKSDEPKDVIEEVTEAVVGKSQEQDS 1779
Cdd:PRK03918  464 IEKELKEIEEKERKLRKELreleKVLKKESELIKLKELAEQLKELEEKLKkynlEELEKKAEEYEKLKEKLIKLKGEIKS 543

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1780 LSENAKledaeatllansakpgvsetfsshddinnylqQLDQLKGRIAELEMEKQK-DRELSQTLENEKNALLTQISAKD 1858
Cdd:PRK03918  544 LKKELE--------------------------------KLEELKKKLAELEKKLDElEEELAELLKELEELGFESVEELE 591

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1859 SELKLLEEEVAKINMLN---QQIQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSignyYQDVTDAQIKNE 1929
Cdd:PRK03918  592 ERLKELEPFYNEYLELKdaeKELEREEKELKKLEEELDKAFEELAetekrlEELRKELEELEKK----YSEEEYEELREE 667

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564376925 1930 --QLESEMQNLKRCVSELEEEKQQLVK--EKTKVESEIRKEYMEKIQGAQKgpgskihAKELQELLKEKQQEVKQLQK 2003
Cdd:PRK03918  668 ylELSRELAGLRAELEELEKRREEIKKtlEKLKEELEEREKAKKELEKLEK-------ALERVEELREKVKKYKALLK 738
PTZ00121 PTZ00121
MAEBL; Provisional
 965-1818 5.78e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 5.78e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  965 KDALQQELEWLRKESEQRKRKLQAALISRKELLQKVSKLEEELAKVREESTKDSLRESEKRELEEDSKNKDDPEKYGTSE 1044
Cdd:PTZ00121 1104 KKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARK 1183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1045 WRELEVSLRLTISEKEVELEGIR-----RDLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEEitENQATIQKFITGT 1119
Cdd:PTZ00121 1184 AEEVRKAEELRKAEDARKAEAARkaeeeRKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEE--RNNEEIRKFEEAR 1261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1120 M-------DAGDGDSAVKETSVSSPPRAGGGEHWKPELEGKIVDLEKEKTQLQKKLQEALISRKAILKKAQEKEKHLKEE 1192
Cdd:PTZ00121 1262 MahfarrqAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEA 1341

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1193 LKEQKDAYRHLQEQFDGQSKENENI-AARLRQLQAKESTDQQLPGTGQQEPTHGSEGLSLEGTEPASESDLHAAQPSHPG 1271
Cdd:PTZ00121 1342 KKAAEAAKAEAEAAADEAEAAEEKAeAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD 1421

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1272 ETATLQATVSVAQIQDQLKEIEVEKEELELKI--SSTTSELTKKSEEVLLLQE--QINEQGLEIQNLKAASHEAKAHTEQ 1347
Cdd:PTZ00121 1422 EAKKKAEEKKKADEAKKKAEEAKKADEAKKKAeeAKKAEEAKKKAEEAKKADEakKKAEEAKKADEAKKKAEEAKKKADE 1501

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1348 LKQELESSQlKIADLEHLKTLQPELETLQKHVGQKEEEVsylvgqlgeKEQTLTTVQTEMEEQERLIKALHTQLEMQAKE 1427
Cdd:PTZ00121 1502 AKKAAEAKK-KADEAKKAEEAKKADEAKKAEEAKKADEA---------KKAEEKKKADELKKAEELKKAEEKKKAEEAKK 1571

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1428 HEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEalkENKSLQEQLSSARDAVEHLTKSLADVESQVSV 1507
Cdd:PTZ00121 1572 AEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAE---EAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK 1648

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1508 QNQEKDAllgklallqEERDKLIVEMDKSLLENQSlgGSCESLKLALGGLTEDKEKLMKELESVRCSKIAESTEWQEKHK 1587
Cdd:PTZ00121 1649 AEELKKA---------EEENKIKAAEEAKKAEEDK--KKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKK 1717

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1588 --ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQE--VYAKLRSAESDKRER---------EKQLQDAEQEMEEMKE 1654
Cdd:PTZ00121 1718 aeELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEkkKIAHLKKEEEKKAEEirkekeaviEEELDEEDEKRRMEVD 1797

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1655 KMRKFAKSKQQKILELEEENDRLRAEAQPVgGANESMEALLSSNASLKEeleritleyktlSKEFEALMAEKNTLSEETR 1734
Cdd:PTZ00121 1798 KKIKDIFDNFANIIEGGKEGNLVINDSKEM-EDSAIKEVADSKNMQLEE------------ADAFEKHKFNKNNENGEDG 1864

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1735 NlklqveaqelkqASLETTEKSDEPKDVIEEVTEAVVGKSQEQDslsenakleDAEATLLANSAKPGVSETFSSHDDINN 1814
Cdd:PTZ00121 1865 N------------KEADFNKEKDLKEDDEEEIEEADEIEKIDKD---------DIEREIPNNNMAGKNNDIIDDKLDKDE 1923


                  ....
gi 564376925 1815 YLQQ 1818
Cdd:PTZ00121 1924 YIKR 1927
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2077-2307 5.81e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 5.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2077 KLKKELQSNKESIKSQIKQKdEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQS 2156
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAEL-EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2157 LDSTLAQLAaftksmsslqddrdRVIDEAKKWEQRFGDAIQTKEEEVRLKEENCTALKDQLRQMTIHMEELKITVSRLEH 2236
Cdd:COG4942    99 LEAQKEELA--------------ELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564376925 2237 DKEiwesKAQTELQHQQKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLEK 2307
Cdd:COG4942   165 LRA----ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 50-393 6.11e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 6.11e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925    50 LDRLADAEKLVLElkdiISKQDAQLQQKDEALQEEKKGAESKIKKIKLHAKAKITSLNKQIEELKTQGGAASPPEVQAEE 129
Cdd:TIGR02169  708 SQELSDASRKIGE----IEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALND 783

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   130 LSKHDKSSteeemEVEKIKHELQEKEKLISNLQAQLDQA-QSEQASQLDKSSAEmedfvlmrQKLQEKEELIGALQTQLS 208
Cdd:TIGR02169  784 LEARLSHS-----RIPEIQAELSKLEEEVSRIEARLREIeQKLNRLTLEKEYLE--------KEIQELQEQRIDLKEQIK 850

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   209 QTQAEQA---AQLSSMQQVVREKdarfETQVRLHEDELLQLVTQSDvetEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQ 285
Cdd:TIGR02169  851 SIEKEIEnlnGKKEELEEELEEL----EAALRDLESRLGDLKKERD---ELEAQLRELERKIEELEAQIEKKRKRLSELK 923

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   286 KELTSAEQRNQDLSQQLQLLEaehstlrntmeaERQESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQYGTL 365
Cdd:TIGR02169  924 AKLEALEEELSEIEDPKGEDE------------EIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDEL 991

                          330       340
                   ....*....|....*....|....*...
gi 564376925   366 QQRHETEMEEKTACISLLQKNEQELQSA 393
Cdd:TIGR02169  992 KEKRAKLEEERKAILERIEEYEKKKREV 1019
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1699-2236 1.16e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.66  E-value: 1.16e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1699 ASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQELKQASLETTEKSdepkdvIEEVTEAVVGKSQEQD 1778
Cdd:PRK02224  202 KDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAE------IEDLRETIAETERERE 275

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1779 SLSENAKLEDAEATLLANSAKPGVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKD 1858
Cdd:PRK02224  276 ELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLE 355

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1859 SELKLLEEEVAKINmlnqqiqeelSRVTKLKETAEEEKDDLEErLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNL 1938
Cdd:PRK02224  356 ERAEELREEAAELE----------SELEEAREAVEDRREEIEE-LEEEIEELRERFGDAPVDLGNAEDFLEELREERDEL 424

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1939 KRCVSELEEEKQqlvkektkvESEIRKEYMEKIQGAQKGP--GSKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALE 2016
Cdd:PRK02224  425 REREAELEATLR---------TARERVEEAEALLEAGKCPecGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVE 495

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2017 KTVKALE-FVHTESQKD-LDATKGNLAQAVEHHKKAQAElssfkillDDTQSEAARVLADNLKLKKElqsNKESIKSQIK 2094
Cdd:PRK02224  496 ERLERAEdLVEAEDRIErLEERREDLEELIAERRETIEE--------KRERAEELRERAAELEAEAE---EKREAAAEAE 564

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2095 QKDEDLLRRLEQAEEKhRKEKKNMQEKLDALHREKAHVEDTLAEIQvSLTRKDKDMKELQQSLDSTLAQLAAFTKSM-SS 2173
Cdd:PRK02224  565 EEAEEAREEVAELNSK-LAELKERIESLERIRTLLAAIADAEDEIE-RLREKREALAELNDERRERLAEKRERKRELeAE 642

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564376925 2174 LQDDRdrvIDEAKKWEQRFGDAIQTKEEEVRLKEENCTALKDQLRQMTIHMEELKITVSRLEH 2236
Cdd:PRK02224  643 FDEAR---IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREA 702
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2385-2873 1.20e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.68  E-value: 1.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2385 KEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALETIKKESLEqkaqLDSFVKSMSSLQDDRDRivsdYRQLEERH 2464
Cdd:PRK03918  231 KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEE----LEEKVKELKELKEKAEE----YIKLSEFY 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2465 LSVILEKDELIQDAAaennKLKEEIRGLRGHMDDLNSENAK---LDAELIQYRRDLNEVIT-IKDSQQRQLLEAQLQQNK 2540
Cdd:PRK03918  303 EEYLDELREIEKRLS----RLEEEINGIEERIKELEEKEERleeLKKKLKELEKRLEELEErHELYEEAKAKKEELERLK 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2541 ELR--NECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTAL-----------------HEEGALAVYH 2601
Cdd:PRK03918  379 KRLtgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELkkakgkcpvcgrelteeHRKELLEEYT 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2602 AQLRVREEEVQKLTAALSSSQKRTVDLQEEL-----VCVQKEASKKVSEIEDKLK-----------RELKHLHHNAGIMR 2665
Cdd:PRK03918  459 AELKRIEKELKEIEEKERKLRKELRELEKVLkkeseLIKLKELAEQLKELEEKLKkynleelekkaEEYEKLKEKLIKLK 538

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2666 NETETAE---ERVAELARDLVEMEQKLLTVTKENKDLTAQIQAFGKSMSSLQDSRDHATE-------ELSDLKKKYDASL 2735
Cdd:PRK03918  539 GEIKSLKkelEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEpfyneylELKDAEKELEREE 618

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2736 KELAQLKGRQDLGRESDVLSQAAFplttsENISSRLEKLNQQLTSKD-----EQLLHLSSELESSHNQVQSFTKAMTSLQ 2810
Cdd:PRK03918  619 KELKKLEEELDKAFEELAETEKRL-----EELRKELEELEKKYSEEEyeelrEEYLELSRELAGLRAELEELEKRREEIK 693

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564376925 2811 NERDHLWNELEKFRKSEEgkqrsaapsaasspaEVQSLKKAMSSLQNDRDRlLKELKNLQQQY 2873
Cdd:PRK03918  694 KTLEKLKEELEEREKAKK---------------ELEKLEKALERVEELREK-VKKYKALLKER 740
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1441-1645 1.43e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 1.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1441 ELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSLADVESQVSVQNQEKDALLGKLA 1520
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1521 LLQEERDKLIVEMDKSllenqslgGSCESLKLALGG----LTEDKEKLMKELESVRCSKIAESTEWQEKHKELQKEYEVL 1596
Cdd:COG4942   101 AQKEELAELLRALYRL--------GRQPPLALLLSPedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 564376925 1597 LQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDA 1645
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1927-2700 1.50e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.21  E-value: 1.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1927 KNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEY-MEKIQGAQKGPGSKIHAKELQELLKEKQQEVKQLQKDC 2005
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQlKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2006 IRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSN 2085
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2086 KESIKSQIKQKDEDLLRRLEQAEEKhrkekknmqEKLDALHREKAHVEDTLAEIQvsltRKDKDMKELQQSLDSTLAQLA 2165
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEE---------EELEKLQEKLEQLEEELLAKK----KLESERLSSAAKLKEEELELK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2166 AFTKSMSSLQDDRDRVIDEAKKWEQRFGDAIQTKEEEVRLKEENCTALKDQLRQMTIHMEELKITVSRLEHDKEIWESKA 2245
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2246 QTELQHQQKAYDKLQEE--NKELMSQLEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQE 2323
Cdd:pfam02463  481 KLQEQLELLLSRQKLEErsQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEV 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2324 ADIQNCKFNCEQLETDLTASRELTTRLHDE---INVKEQKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLSQEEEE 2400
Cdd:pfam02463  561 EERQKLVRALTELPLGARKLRLLIPKLKLPlksIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKES 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2401 NLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDdrdrivsdyrQLEERHLSVILEKDELIQDAAA 2480
Cdd:pfam02463  641 AKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESE----------LAKEEILRRQLEIKKKEQREKE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2481 ENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLN----EVITIKDSQQRQLLEAQLQQNKELRNECVKLEGRLKGS 2556
Cdd:pfam02463  711 ELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEeeeeEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEE 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2557 EAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHEEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQ 2636
Cdd:pfam02463  791 EKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQ 870

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564376925  2637 KEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAEER-VAELARDLVEMEQKLLTVTKENKDLT 2700
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKlNLLEEKENEIEERIKEEAEILLKYEE 935
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 135-361 1.78e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.23  E-value: 1.78e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  135 KSSTEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEKEELIGALQTQLSQTQAEQ 214
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  215 AAQLSSMQQVVRekdarfeTQVRLHEDELLQLVTQSDvetEVQQKLRVMQRkLEEHEEALLGRAQVVDLLQKELTSAEQR 294
Cdd:COG4942   100 EAQKEELAELLR-------ALYRLGRQPPLALLLSPE---DFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAE 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925  295 NQDLSQQLQLLEAEHSTLRNTMEAERQESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQ 361
Cdd:COG4942   169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1301-1895 1.83e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.87  E-value: 1.83e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1301 LKISSTTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIADL-EHLKTLQPELETLQKHV 1379
Cdd:TIGR04523   40 KKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSEIKNDKEQK 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1380 GQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHEE----------------------------- 1430
Cdd:TIGR04523  120 NKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEElenelnllekeklniqknidkiknkllkl 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1431 ------------RLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQE-----------QLSSA 1487
Cdd:TIGR04523  200 elllsnlkkkiqKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNkikkqlsekqkELEQN 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1488 RDAVEHLTKSLADVESQVSVQNQEKDALLGKLALLQ-EERDKLIVEMDKSLLENQSlggsceslklALGGLTEDKEKLMK 1566
Cdd:TIGR04523  280 NKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSElKNQEKKLEEIQNQISQNNK----------IISQLNEQISQLKK 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1567 ELESVRCSKIAESTEWQEKHKELQ---KEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQ 1643
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEklkKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1644 DAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEaqpvggaNESMEALLSSNASLKEELERITLEYKTLSKEFEALM 1723
Cdd:TIGR04523  430 RLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESL-------ETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLN 502

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1724 AEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKdvieevteaVVGKSQEQDSLSENAKLEDAEatllansakpgvs 1803
Cdd:TIGR04523  503 EEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESK---------ISDLEDELNKDDFELKKENLE------------- 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1804 etfsshDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELS 1883
Cdd:TIGR04523  561 ------KEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIK 634

                          650
                   ....*....|..
gi 564376925  1884 RVTKLKETAEEE 1895
Cdd:TIGR04523  635 NIKSKKNKLKQE 646
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1304-1903 1.99e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.97  E-value: 1.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1304 SSTTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEA-----KAHTEQLKQELESSQLKIADL--------EHLKTLQP 1370
Cdd:pfam15921  220 SAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKielllQQHQDRIEQLISEHEVEITGLtekassarSQANSIQS 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1371 ELETLQKhvgQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLikalhtqLEMQAKEHEERLKQVQVEICELKKQPKELE 1450
Cdd:pfam15921  300 QLEIIQE---QARNQNSMYMRQLSDLESTVSQLRSELREAKRM-------YEDKIEELEKQLVLANSELTEARTERDQFS 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1451 EESKAKQQLQRKLQAALISRKEAL----KENKSLQEQLSSARDAVEHLTKSLADveSQVSVQNQEkdallgklALLQEER 1526
Cdd:pfam15921  370 QESGNLDDQLQKLLADLHKREKELslekEQNKRLWDRDTGNSITIDHLRRELDD--RNMEVQRLE--------ALLKAMK 439

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1527 DKLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESVRCSKIAestewqekhkelqkeyevLLQSYENVSNE 1606
Cdd:pfam15921  440 SECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMT------------------LESSERTVSDL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1607 AERIQHVVESVRQEKQEVyAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGG 1686
Cdd:pfam15921  502 TASLQEKERAIEATNAEI-TKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1687 ANESMEALLSSNASLKEELERITLEYKtlskEFEALMAEKNTLSEE--TRNLKLQVEAQELKQASLETTEKSDEPKDVIE 1764
Cdd:pfam15921  581 HGRTAGAMQVEKAQLEKEINDRRLELQ----EFKILKDKKDAKIREleARVSDLELEKVKLVNAGSERLRAVKDIKQERD 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1765 EVTEAVVGKSQEQDSLSE-------NAKLEDAEATLLANSAKPGVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQKdr 1837
Cdd:pfam15921  657 QLLNEVKTSRNELNSLSEdyevlkrNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQK-- 734

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564376925  1838 elsqtlenEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEERL 1903
Cdd:pfam15921  735 --------QITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGEL 792
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1295-1972 3.19e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.44  E-value: 3.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1295 EKEELELKISSTTSELTKKSEEVLLLQEQINEQGLEIQNLKA-ASHEAKAHTEQLKQELESSQLKIADLEHLKTLQPELE 1373
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEeLKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1374 TLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHEERLKQVQVEICELKKQPKELEEES 1453
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1454 KAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSLADVESQVSVQNQEKDALLGKLALLQEERDKLIVEM 1533
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1534 DKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHV 1613
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1614 VESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELE---EENDRLRAEAQPVGGANES 1690
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAkvvEGILKDTELTKLKESAKAK 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1691 MEALLSSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAV 1770
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLA 724

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1771 VGKSQEQDSLSENAKLEDAEATLLANSAKPGVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQ------KDRELSQTLE 1844
Cdd:pfam02463  725 DRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVeeekeeKLKAQEEELR 804

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1845 NEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDA 1924
Cdd:pfam02463  805 ALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKL 884

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*...
gi 564376925  1925 QIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQ 1972
Cdd:pfam02463  885 KDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLK 932
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1156-1997 4.40e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.67  E-value: 4.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1156 DLEKEKTQLQKKLQEALISRKAILKKAQEKEKHLKEELKEQKDAYRHLQEQFD--------GQSKENENIAARLRQLQAK 1227
Cdd:pfam02463  166 RLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKleleeeylLYLDYLKLNEERIDLLQEL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1228 ESTDQQLPGTGQQEPTHGSEGLSLEGTEPASESDLHAAQPSHPGETATLQATVSVAQIQDQLKEIEVEKEELELKISSTT 1307
Cdd:pfam02463  246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1308 SELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIADLEHLKTLQPELETLQKHVGQKEEEVS 1387
Cdd:pfam02463  326 AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1388 YLVGQLGEKEQTLTTVQTEMEEQERLIKALhtQLEMQAKEHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAAL 1467
Cdd:pfam02463  406 EAQLLLELARQLEDLLKEEKKEELEILEEE--EESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1468 ISRKEALKENKsLQEQLSSARDAVEHLTKSLADVESQVSVQNQEKDALLGKLALLQE--ERDKLIVEMDKSLLENQSLGG 1545
Cdd:pfam02463  484 EQLELLLSRQK-LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEnyKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1546 ScESLKLALGGLTEDKEKLMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVY 1625
Cdd:pfam02463  563 R-QKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1626 AKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGANES----------MEALL 1695
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQrekeelkklkLEAEE 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1696 SSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAVvgKSQ 1775
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKL--KAQ 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1776 EQDSLSENAKLEDAEATLLANSAKPGVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQIS 1855
Cdd:pfam02463  800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1856 AKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEM 1935
Cdd:pfam02463  880 EEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEE 959

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925  1936 QNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPGSKIHAKELQELLKEKQQE 1997
Cdd:pfam02463  960 ERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKE 1021
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 674-1107 4.77e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 4.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  674 HQGELERLKTQVLELETSLHTAKETHEKNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLYRVKELDVLGE 753
Cdd:COG1196   335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  754 LRAQVRELETSLAEAEKQrgldyesqraqhnlLTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQ 833
Cdd:COG1196   415 RLERLEEELEELEEALAE--------------LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  834 TKESEVLEGAERmkdisKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEK 913
Cdd:COG1196   481 ELLEELAEAAAR-----LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED 555

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  914 FSLGVE-IKTLKEQlsLLSRAEGAKKEQVEDSGAESSPKHGPHESSAQEPVCKDALQQELEWLRKESEQRKRKLQAALIS 992
Cdd:COG1196   556 DEVAAAaIEYLKAA--KAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLE 633

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  993 RKELLQKvsKLEEELAKVREESTKDSLRESEKRELEEDSKNKDDPEKYGTSEWRELEVSLRLTISEKEVELEGIRRDLKE 1072
Cdd:COG1196   634 AALRRAV--TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAE 711

                         410       420       430
                  ....*....|....*....|....*....|....*
gi 564376925 1073 KAAAEEELQALVQRMTQDLQNKTKQIDLLQEEITE 1107
Cdd:COG1196   712 AEEERLEEELEEEALEEQLEAEREELLEELLEEEE 746
PTZ00121 PTZ00121
MAEBL; Provisional
 679-1136 5.04e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.84  E-value: 5.04e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  679 ERLKTQVLELETSLHTAKETHEKNLSEKAKEISSLTQLTKEFKESAEEARSTltavceerDQLLYRVKELDVLGELRAQV 758
Cdd:PTZ00121 1421 DEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKA--------DEAKKKAEEAKKADEAKKKA 1492

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  759 RELETSLAEAEKQRgldyesqraqhnllteqihslsiEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESE 838
Cdd:PTZ00121 1493 EEAKKKADEAKKAA-----------------------EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD 1549

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  839 VLEGAERMKDIS--KEMEELSQALSQKELEIAQMDQL-LLEKKKDVETLQQTIQEKDQQVTELSFSMTEKmvqLNEEKFS 915
Cdd:PTZ00121 1550 ELKKAEELKKAEekKKAEEAKKAEEDKNMALRKAEEAkKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK---IKAEELK 1626

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  916 LGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAESSPKHGPHESSAQEPVCK-DALQQELEWLRKESEQRKRKLQaalisRK 994
Cdd:PTZ00121 1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKaEEAKKAEEDEKKAAEALKKEAE-----EA 1701

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  995 ELLQKVSKLEEELAKVREESTKDslrESEKRELEEDSKNKDDPEKYGTSEWRELEVSLRLTISEKEVELEGIRRDLKEKA 1074
Cdd:PTZ00121 1702 KKAEELKKKEAEEKKKAEELKKA---EEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564376925 1075 AA-EEELQALVQRMTQDLQNKTKQIDLLQEEITENQATIQKFITGTMDAgdGDSAVKETSVSS 1136
Cdd:PTZ00121 1779 AViEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEM--EDSAIKEVADSK 1839
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2270-3067 5.37e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 52.74  E-value: 5.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2270 LEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEG---IIKQQEADIQNCKFNCEQLETDLTASREL 2346
Cdd:TIGR00606  188 LETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESsreIVKSYENELDPLKNRLKEIEHNLSKIMKL 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2347 TTRLH--DEINVKEQKIISLLSGKEEaiqvaiaELHQQHSKEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALET 2424
Cdd:TIGR00606  268 DNEIKalKSRKKQMEKDNSELELKME-------KVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQ 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2425 IKKESLEQKAQLdsfvksmsSLQDDRDRIVSDYRQLEERHLSVILEKDELIQDAAAE---NNKLKEEIRGLRGHMDDLNS 2501
Cdd:TIGR00606  341 EKTELLVEQGRL--------QLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErqiKNFHTLVIERQEDEAKTAAQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2502 ENAKLDAELIQYRRDLNEVITIKDSQQRQL------LEAQLQQNKELRNECVKLEGRLKGSEAEKQSLQMSLDALQEENQ 2575
Cdd:TIGR00606  413 LCADLQSKERLKQEQADEIRDEKKGLGRTIelkkeiLEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEK 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2576 GLSKEIKSfKEQLTALHEEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKVSEIEDKL----- 2650
Cdd:TIGR00606  493 NSLTETLK-KEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLgyfpn 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2651 KRELKHLHHNagiMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLTAQIQAFGKSMSSLQDSRDHATEeLSDLKKK 2730
Cdd:TIGR00606  572 KKQLEDWLHS---KSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESD-LERLKEE 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2731 YDASLKELAQLKGRQDLG----RESDVLSQAAFPL-----TTSENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQS 2801
Cdd:TIGR00606  648 IEKSSKQRAMLAGATAVYsqfiTQLTDENQSCCPVcqrvfQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDE 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2802 FTKAMTSLQNERDHLWNELEKFRKSEEGKQRSAAPSAASSPAEVQSLKKAMSSLQNDRDrLLKELKNLQQQYLQMNQEIT 2881
Cdd:TIGR00606  728 MLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKV-CLTDVTIMERFQMELKDVER 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2882 ELRPLKAQLQESQdqtkaLQMMKEELRQENLSWQHELHQLRVEKnswelherrmkEQYLMAISDKDQQLGHLQNLLRELR 2961
Cdd:TIGR00606  807 KIAQQAAKLQGSD-----LDRTVQQVNQEKQEKQHELDTVVSKI-----------ELNRKLIQDQQEQIQHLKSKTNELK 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2962 sSSQTQILPTQYQRQASSgtsaalDGSQNLVYETDCLRTQLNDSLKEIHQKELRIQQLNSKFSQLLEEKNilsTQLRDAN 3041
Cdd:TIGR00606  871 -SEKLQIGTNLQRRQQFE------EQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKE---TSNKKAQ 940

                          810       820
                   ....*....|....*....|....*.
gi 564376925  3042 QSLRDSQHHYSNLFNHCAILERQVQQ 3067
Cdd:TIGR00606  941 DKVNDIKEKVKNIHGYMKDIENKIQD 966
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1561-2033 8.62e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 8.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1561 KEKLMKELESVRcSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQ--EVYAKLRSAESDKRER 1638
Cdd:COG4717    66 PELNLKELKELE-EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAEL 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1639 EKQLQDAeqemeemkekmrkfaKSKQQKILELEEENDRLRAEAQPVggANESMEALLSSNASLKEELERITLEYKTLSKE 1718
Cdd:COG4717   145 PERLEEL---------------EERLEELRELEEELEELEAELAEL--QEELEELLEQLSLATEEELQDLAEELEELQQR 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1719 FEALMAEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTeAVVGKSQEQDSLSENAKLEDAEATLLANSA 1798
Cdd:COG4717   208 LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAA-ALLALLGLGGSLLSLILTIAGVLFLVLGLL 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1799 KPGVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQI 1878
Cdd:COG4717   287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1879 QEELSRVTKLKETAEEEKDDLEERLM---------NQLAELNGSIGNYYQDVTD--AQIKNEQLESEMQNLKRCVSELEE 1947
Cdd:COG4717   367 ELEQEIAALLAEAGVEDEEELRAALEqaeeyqelkEELEELEEQLEELLGELEEllEALDEEELEEELEELEEELEELEE 446

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1948 EKQQLVKEKTKVESEIrkEYMEKiqgaqkgpgskihAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHT 2027
Cdd:COG4717   447 ELEELREELAELEAEL--EQLEE-------------DGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYRE 511


                  ....*.
gi 564376925 2028 ESQKDL 2033
Cdd:COG4717   512 ERLPPV 517
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2505-2797 8.68e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 8.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2505 KLDAELIQYRRDLNEvitikdsQQRQLLEAQLQQNKELRNEcvkLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSF 2584
Cdd:COG1196   224 ELEAELLLLKLRELE-------AELEELEAELEELEAELEE---LEAELAELEAELEELRLELEELELELEEAQAEEYEL 293

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2585 KEQLTALheEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELvcvqKEASKKVSEIEDKLKRELKHLHHNAgim 2664
Cdd:COG1196   294 LAELARL--EQDIARLEERRRELEERLEELEEELAELEEELEELEEEL----EELEEELEEAEEELEEAEAELAEAE--- 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2665 rNETETAEERVAELARDLVEMEQKLLTVTKENKDLTAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGR 2744
Cdd:COG1196   365 -EALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 564376925 2745 QDLGRESDVLSQAAfpLTTSENISSRLEKLNQQLTSKDEQLLHLSSELESSHN 2797
Cdd:COG1196   444 LEEAAEEEAELEEE--EEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1283-1914 9.43e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.60  E-value: 9.43e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1283 AQIQDQLKEIEVEKEELELKISSTTSELTKKSEEVLLLQEQINEqgleiqnlkaasheakahTEQLKQELESSQLKIADL 1362
Cdd:PRK03918  189 ENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE------------------LEELKEEIEELEKELESL 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1363 E-HLKTLQPELETLQKHVGQKEEEVSylvgQLGEKEQTLTTVQTEMEEQERLIKaLHTQLEMQAKEHEERLKQVQVEICE 1441
Cdd:PRK03918  251 EgSKRKLEEKIRELEERIEELKKEIE----ELEEKVKELKELKEKAEEYIKLSE-FYEEYLDELREIEKRLSRLEEEING 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1442 LKKQPKELEEESKAKQQLQRKLQaALISRKEALKENKSLQEQLSSARDAVEHLTKSLAdvesqvsvqNQEKDALLGKLAL 1521
Cdd:PRK03918  326 IEERIKELEEKEERLEELKKKLK-ELEKRLEELEERHELYEEAKAKKEELERLKKRLT---------GLTPEKLEKELEE 395

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1522 LQEERDKLIVEMDKSLLENQSLGGSCESLKLAlggltedkeklMKELESVRCSKIAESTEWQEKH-KELQKEYEVLLqsy 1600
Cdd:PRK03918  396 LEKAKEEIEEEISKITARIGELKKEIKELKKA-----------IEELKKAKGKCPVCGRELTEEHrKELLEEYTAEL--- 461

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1601 ENVSNEAERIQHVVESVRQEKQEVyAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1680
Cdd:PRK03918  462 KRIEKELKEIEEKERKLRKELREL-EKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGE 540

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1681 AQPVGGANESMEALLSSNASLKEELERITLEYKTLSKEFEALMAEK-NTLSEETRNL-KLQVEAQELKQASLETTEKSDE 1758
Cdd:PRK03918  541 IKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESvEELEERLKELePFYNEYLELKDAEKELEREEKE 620

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1759 PKDVIEEVTEAvvgksqEQDSLSENAKLEDAEATLLANSAKPGVSEtfssHDDINN-YLQQLDQLKGRIAELEMEKQKDR 1837
Cdd:PRK03918  621 LKKLEEELDKA------FEELAETEKRLEELRKELEELEKKYSEEE----YEELREeYLELSRELAGLRAELEELEKRRE 690

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925 1838 ELSQTLENEKNAlLTQISAKDSELKLLEeevakinmlnqqiqEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSI 1914
Cdd:PRK03918  691 EIKKTLEKLKEE-LEEREKAKKELEKLE--------------KALERVEELREKVKKYKALLKERALSKVGEIASEI 752
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
722-943 1.44e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.79  E-value: 1.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  722 ESAEEARSTLTAVCEE--RDQLLYRVKELD-VLGELRAQVRELETSLAEAEKQRgLDYesqRAQHNLLteqihSLSIEAK 798
Cdd:COG3206   145 PDPELAAAVANALAEAylEQNLELRREEARkALEFLEEQLPELRKELEEAEAAL-EEF---RQKNGLV-----DLSEEAK 215

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  799 SKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAErmkdiSKEMEELSQALSQKELEIAQMDQLLLEKK 878
Cdd:COG3206   216 LLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ-----SPVIQQLRAQLAELEAELAELSARYTPNH 290

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564376925  879 KDVETLQQTIQEKDQQVTElsfsmtekmvQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVED 943
Cdd:COG3206   291 PDVIALRAQIAALRAQLQQ----------EAQRILASLEAELEALQAREASLQAQLAQLEARLAE 345
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1843-2375 1.59e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.81  E-value: 1.59e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1843 LENEKNALL---TQISAKDSElklleEEVAKINMLNQQI---QEELSRVTKLKETAEEEKDDLEERL------MNQLAEL 1910
Cdd:PRK02224  182 LSDQRGSLDqlkAQIEEKEEK-----DLHERLNGLESELaelDEEIERYEEQREQARETRDEADEVLeeheerREELETL 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1911 NGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEK--TKVESEIRKEYMEKIQGAQKgpgskihakELQ 1988
Cdd:PRK02224  257 EAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAglDDADAEAVEARREELEDRDE---------ELR 327

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1989 ELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEfvhtESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEA 2068
Cdd:PRK02224  328 DRLEECRVAAQAHNEEAESLREDADDLEERAEELR----EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDA 403

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2069 ARVLADNLKLKKELQSNKESIKSQIKQKDEDLL---RRLEQAEEKHRKEK--KNMQEKLDALHREKahVEDTLAEIQvSL 2143
Cdd:PRK02224  404 PVDLGNAEDFLEELREERDELREREAELEATLRtarERVEEAEALLEAGKcpECGQPVEGSPHVET--IEEDRERVE-EL 480

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2144 TRKDKDMKELQQSLDSTLAQLaaftKSMSSLQDDRDRVIDEAKKWEQRfgdaIQTKEEEVRLKEENCTALKDQlrqmtih 2223
Cdd:PRK02224  481 EAELEDLEEEVEEVEERLERA----EDLVEAEDRIERLEERREDLEEL----IAERRETIEEKRERAEELRER------- 545

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2224 meelkitVSRLEHDKEIWESKAQTELQHQQKAYDKLQEENKEL---------MSQLEEAGQLYHDSKNELTKLESELKSL 2294
Cdd:PRK02224  546 -------AAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLaelkeriesLERIRTLLAAIADAEDEIERLREKREAL 618

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2295 KDQSTDLKNSLEKCREHENNLEGI-----IKQQEADIQNCKFNCEQLETDLTASRELTTRLHDEINVKEQKIISLLSGKE 2369
Cdd:PRK02224  619 AELNDERRERLAEKRERKRELEAEfdearIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRE 698


                  ....*.
gi 564376925 2370 EAIQVA 2375
Cdd:PRK02224  699 RREALE 704
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1408-1681 1.76e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 50.70  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1408 EEQERLIKALHtqlEMQAkeheerlkqvqVEICELKkQPKELEEESKAKQqLQRKLQAALISRKEALKENKSLQEQLSSA 1487
Cdd:PRK05771   16 SYKDEVLEALH---ELGV-----------VHIEDLK-EELSNERLRKLRS-LLTKLSEALDKLRSYLPKLNPLREEKKKV 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1488 R-----DAVEHLTKSLADVESQVSVQNQEKDALLGKLALLQEERDklIVEMDKSL-LENQSLGGScESLKLALGGLTEDK 1561
Cdd:PRK05771   80 SvksleELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIE--RLEPWGNFdLDLSLLLGF-KYVSVFVGTVPEDK 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1562 EKLMKELESVRCSKIAESTEwqEK-------HKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVyaklrsaesd 1634
Cdd:PRK05771  157 LEELKLESDVENVEYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL---------- 224

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 564376925 1635 kREREKQLQDAEqemeemkEKMRKFAKSKQQKILELEE--ENDRLRAEA 1681
Cdd:PRK05771  225 -EEIEKERESLL-------EELKELAKKYLEELLALYEylEIELERAEA 265
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1274-1492 1.77e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 1.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1274 ATLQATVSVAQIQDQLKEIEVEKEELELKISSTTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELE 1353
Cdd:COG4942    14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1354 SSQLKIADLEHLktLQPELETLQKHVGQKEEEV---SYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHEE 1430
Cdd:COG4942    94 ELRAELEAQKEE--LAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925 1431 RLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVE 1492
Cdd:COG4942   172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1661-2200 1.97e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.67  E-value: 1.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1661 KSKQQKILELEEENDRLRAEAQPVGGANESMEALLSSNASLKEELERITLEYKTLSKEFEAL---MAEKNTLSEETRNLK 1737
Cdd:PRK01156  176 DMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLksaLNELSSLEDMKNRYE 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1738 LQV-EAQELKQASLETTEKSDEPKDVIEEVTEAVVGKSQEQ--DSLSENAKLEDAEATLlansakPGVSETFSSHDDINN 1814
Cdd:PRK01156  256 SEIkTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYinDYFKYKNDIENKKQIL------SNIDAEINKYHAIIK 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1815 YLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVtklKETAEE 1894
Cdd:PRK01156  330 KLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQ---EIDPDA 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1895 EKDDLEErLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNL------------------KRCVSELEEEKQQLVKEK 1956
Cdd:PRK01156  407 IKKELNE-INVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLngqsvcpvcgttlgeeksNHIINHYNEKKSRLEEKI 485

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1957 TKVESEIRKEYMEKIQgaQKGPGSKIHAKELQELLKEKQQeVKQLQKDCIRYLGRISAL-EKTVKALEFVHTESQKDLda 2035
Cdd:PRK01156  486 REIEIEVKDIDEKIVD--LKKRKEYLESEEINKSINEYNK-IESARADLEDIKIKINELkDKHDKYEEIKNRYKSLKL-- 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2036 tkGNLAQAVEHHKKAQAELSSFKILLDDTQS-EAARVLADNLKLKKELQSNKESIKSQIKQ---KDEDLLRRLE----QA 2107
Cdd:PRK01156  561 --EDLDSKRTSWLNALAVISLIDIETNRSRSnEIKKQLNDLESRLQEIEIGFPDDKSYIDKsirEIENEANNLNnkynEI 638

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2108 EEKHRKEKKnMQEKLDALHREKAH---VEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQ--------- 2175
Cdd:PRK01156  639 QENKILIEK-LRGKIDNYKKQIAEidsIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRtrinelsdr 717

                         570       580
                  ....*....|....*....|....*.
gi 564376925 2176 -DDRDRVIDEAKKWEQRFGDAIQTKE 2200
Cdd:PRK01156  718 iNDINETLESMKKIKKAIGDLKRLRE 743
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 785-1019 2.22e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 2.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  785 LLTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKE 864
Cdd:COG4942    10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  865 LEIAQMDQLLLEKKKDVETLQQTIQEKDQQVTEL----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAE 934
Cdd:COG4942    90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  935 GAKKEQVEDSGAESSPKHGPHESSaqepvcKDALQQELEWLRKESEQRKRKLQAALISRKELLQKVSKLEEELAKVREES 1014
Cdd:COG4942   170 EAERAELEALLAELEEERAALEAL------KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                  ....*
gi 564376925 1015 TKDSL 1019
Cdd:COG4942   244 PAAGF 248
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2448-2727 2.25e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 2.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2448 DDRDRIVSDY-------RQLEErhlsvileKDELIQDAAAENNKLKEEIRGLRGHMDDLNSENAKLdAELIQYRRDLNEV 2520
Cdd:COG4913   593 DDRRRIRSRYvlgfdnrAKLAA--------LEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV 663

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2521 itikDSQQRQL--LEAQLQQ----NKELRnecvKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHEE 2594
Cdd:COG4913   664 ----ASAEREIaeLEAELERldasSDDLA----ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDR 735

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2595 GALAVYHAQLRVREEEVQKLTAALSSSQKRTV--DLQEELVCVQKEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAE 2672
Cdd:COG4913   736 LEAAEDLARLELRALLEERFAAALGDAVERELreNLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLP 815

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2673 ERVAELAR----DLVEMEQKLLT-VTKENKDLTAQIQafgksmSSLQDSRDHATEELSDL 2727
Cdd:COG4913   816 EYLALLDRleedGLPEYEERFKElLNENSIEFVADLL------SKLRRAIREIKERIDPL 869
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1314-1476 2.35e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 2.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1314 SEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIA--DLEHLKTLQPELETLQKHVGQKEEEVSYLVG 1391
Cdd:COG4913   287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRgnGGDRLEQLEREIERLERELEERERRRARLEA 366

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1392 QLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRK 1471
Cdd:COG4913   367 LLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALR 446


                  ....*
gi 564376925 1472 EALKE 1476
Cdd:COG4913   447 DALAE 451
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1587-2154 2.35e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 2.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1587 KELQKEYEVLLQSYENvsneaerIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKqqk 1666
Cdd:PRK03918  175 KRRIERLEKFIKRTEN-------IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELE--- 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1667 iLELEEENDRLRAEAQPVGGANESMEALLSSNASLKEELERITlEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQELK 1746
Cdd:PRK03918  245 -KELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1747 QASLETT-EKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKPGVSETFSSHDDINNylqQLDQLKGR 1825
Cdd:PRK03918  323 INGIEERiKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEK---ELEELEKA 399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1826 IAELEMEKQKDRELSQTLENEKNALLTQISA-KDSELK------LLEEEVAKinMLNQQIQEELSRVTKLKETAEEEKDD 1898
Cdd:PRK03918  400 KEEIEEEISKITARIGELKKEIKELKKAIEElKKAKGKcpvcgrELTEEHRK--ELLEEYTAELKRIEKELKEIEEKERK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1899 LEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRcVSELEEEKQQLVKEKTKVESEIR--KEYMEKIQGAQK 1976
Cdd:PRK03918  478 LRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEE-LEKKAEEYEKLKEKLIKLKGEIKslKKELEKLEELKK 556

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1977 gpgskiHAKELQELLKEKQQEVKQLQKDcIRYLG--RISALEKTVKALEFVHTESQKDLDATKgnlaqavehhkkaqaEL 2054
Cdd:PRK03918  557 ------KLAELEKKLDELEEELAELLKE-LEELGfeSVEELEERLKELEPFYNEYLELKDAEK---------------EL 614

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2055 SSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVED 2134
Cdd:PRK03918  615 EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKK 694

                         570       580
                  ....*....|....*....|
gi 564376925 2135 TLAEIQVSLTRKDKDMKELQ 2154
Cdd:PRK03918  695 TLEKLKEELEEREKAKKELE 714
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2110-2742 2.37e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.40  E-value: 2.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2110 KHRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKelqqSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWE 2189
Cdd:TIGR04523   30 KQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKIN----NSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDL 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2190 QRFGDAIQTKEEEVRLKEENCTALKDQLRqmtihmeelkitvsrlEHDKEIweskaqtelqhqqkayDKLQEENKELMSQ 2269
Cdd:TIGR04523  106 SKINSEIKNDKEQKNKLEVELNKLEKQKK----------------ENKKNI----------------DKFLTEIKKKEKE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2270 LEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNCKfnceQLETDLTASRELTTR 2349
Cdd:TIGR04523  154 LEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNK----SLESQISELKKQNNQ 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2350 LHDEINVKEQKIisllsgkeEAIQVAIAELHQQHSKEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALETIKKES 2429
Cdd:TIGR04523  230 LKDNIEKKQQEI--------NEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN 301

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2430 LEQKAQLDSFVKSMSSLQDDRDRIVSdyrqleerhlSVILEKDELIqdaaaenNKLKEEIRGLRGHMDDLNSENAKLDAE 2509
Cdd:TIGR04523  302 NQKEQDWNKELKSELKNQEKKLEEIQ----------NQISQNNKII-------SQLNEQISQLKKELTNSESENSEKQRE 364

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2510 LiqyRRDLNEVITIKDSQQrqlleAQLQQNKELRNECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLT 2589
Cdd:TIGR04523  365 L---EEKQNEIEKLKKENQ-----SYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETII 436

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2590 ALHEEgaLAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKVSEIEDKLKrELKHLHHNAGIMRNETE 2669
Cdd:TIGR04523  437 KNNSE--IKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEK-ELKKLNEEKKELEEKVK 513

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564376925  2670 TAEERVAELARDLVEMEQKLLTVTKENKDLTAQIQA--FGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQLK 2742
Cdd:TIGR04523  514 DLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ 588
PTZ00121 PTZ00121
MAEBL; Provisional
 1308-1963 3.20e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 3.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1308 SELTKKSEEVLLLQE--QINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIadlehlKTLQPELETLQKHVGQKEEE 1385
Cdd:PTZ00121 1292 ADEAKKAEEKKKADEakKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAA------EAAKAEAEAAADEAEAAEEK 1365

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1386 VSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHEERLKQVQVEIC-ELKKQPKELEEESKAKQQLQRKLQ 1464
Cdd:PTZ00121 1366 AEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAdEAKKKAEEKKKADEAKKKAEEAKK 1445

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1465 AALISRK-EALKENKSLQEQLSSARDAVEHLTKSLADVESQVSVQNQEKDALLGKLALLQEERDKLIVEMDKSLLENQS- 1542
Cdd:PTZ00121 1446 ADEAKKKaEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAd 1525

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1543 -LGGSCESLKLALGGLTEDKEKLMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEK 1621
Cdd:PTZ00121 1526 eAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEK 1605

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1622 QEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQpvggANESMEALLSSNASL 1701
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE----AKKAEEDKKKAEEAK 1681

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1702 KEELERITLEYKTLSKEFEALMAE--KNTLSEETRnlklqvEAQELKQASLETTEKSDEPKDvieevteavvgKSQEQDS 1779
Cdd:PTZ00121 1682 KAEEDEKKAAEALKKEAEEAKKAEelKKKEAEEKK------KAEELKKAEEENKIKAEEAKK-----------EAEEDKK 1744

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1780 LSENAKLEDAEATLLANSAKPGVSETFSSHDDINNYLQQldQLKGRIAELEMEkqKDRELSQTLENEKNalltqISAKDS 1859
Cdd:PTZ00121 1745 KAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE--ELDEEDEKRRME--VDKKIKDIFDNFAN-----IIEGGK 1815

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1860 ELKLLeeevakINMLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAElNGSIGNyyqdvtdaqiKNEQLESEMQNLK 1939
Cdd:PTZ00121 1816 EGNLV------INDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNE-NGEDGN----------KEADFNKEKDLKE 1878

                         650       660
                  ....*....|....*....|....
gi 564376925 1940 RCVSELEEEKQQLVKEKTKVESEI 1963
Cdd:PTZ00121 1879 DDEEEIEEADEIEKIDKDDIEREI 1902
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1662-2261 4.10e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 4.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1662 SKQQKILELEEENDRLRAEaqpvgganesmealLSSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVE 1741
Cdd:PRK03918  204 EVLREINEISSELPELREE--------------LEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIE 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1742 aqELKQASLETTEKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEAtllansakpgvsetfsshddinNYLQQLDQ 1821
Cdd:PRK03918  270 --ELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLS----------------------RLEEEING 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1822 LKGRIAELEMEKQKDRElsqtLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQE----ELSRVTKLKETAEEEKD 1897
Cdd:PRK03918  326 IEERIKELEEKEERLEE----LKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRltglTPEKLEKELEELEKAKE 401

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1898 DLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSEL-EEEKQQLVKEKTKVESEIRKEymekiqgaqk 1976
Cdd:PRK03918  402 EIEE----EISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELtEEHRKELLEEYTAELKRIEKE---------- 467

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1977 gpgskihAKELQELLKEKQQEVKQLQKDcIRYLGRISALEKTVKALEFVHTESQKdldatkgnlaQAVEHHKKAQAELSS 2056
Cdd:PRK03918  468 -------LKEIEEKERKLRKELRELEKV-LKKESELIKLKELAEQLKELEEKLKK----------YNLEELEKKAEEYEK 529

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2057 FKILLDDTQSEaARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhrEKAHVE-DT 2135
Cdd:PRK03918  530 LKEKLIKLKGE-IKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL--EPFYNEyLE 606

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2136 LAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLqddRDRVIDEAKKWEQrfgDAIQTKEEEVRLKEENCTALKD 2215
Cdd:PRK03918  607 LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEEL---RKELEELEKKYSE---EEYEELREEYLELSRELAGLRA 680

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*.
gi 564376925 2216 QLRQMTIHMEELKITVSRLEHDKEIWEsKAQTELQHQQKAYDKLQE 2261
Cdd:PRK03918  681 ELEELEKRREEIKKTLEKLKEELEERE-KAKKELEKLEKALERVEE 725
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1443-2548 4.16e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 49.66  E-value: 4.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1443 KKQPKELEEESKAKQQLQRKLQAALISRKEAlkENKSLQEQLSS-----ARDAVEHLTKsLADVESQV-----SVQNQEK 1512
Cdd:TIGR01612  641 KISPYQVPEHLKNKDKIYSTIKSELSKIYED--DIDALYNELSSivkenAIDNTEDKAK-LDDLKSKIdkeydKIQNMET 717

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1513 DALLGKLALLQEERDKL---IVEMDKSLLE--NQSLGGSCESLK---LALGGLTEDKEKLMKELESVRcSKIAE------ 1578
Cdd:TIGR01612  718 ATVELHLSNIENKKNELldiIVEIKKHIHGeiNKDLNKILEDFKnkeKELSNKINDYAKEKDELNKYK-SKISEiknhyn 796

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1579 --STEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLrsaesdkrerEKQLQDAEQEMEEMKEKM 1656
Cdd:TIGR01612  797 dqINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKV----------DKFINFENNCKEKIDSEH 866

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1657 RKFAKSKQQkiLELEEENDRLRAEAQPVggaNESMEALLSSNASLKEELERITleykTLSKEFEALMAEKNTLSEETRNL 1736
Cdd:TIGR01612  867 EQFAELTNK--IKAEISDDKLNDYEKKF---NDSKSLINEINKSIEEEYQNIN----TLKKVDEYIKICENTKESIEKFH 937

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1737 KLQVEAQELKQASLETTEKSDE-PKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEAT----------LLANSAKPgvset 1805
Cdd:TIGR01612  938 NKQNILKEILNKNIDTIKESNLiEKSYKDKFDNTLIDKINELDKAFKDASLNDYEAKnnelikyfndLKANLGKN----- 1012

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1806 fsshdDINNYLQQLDQLKGRIAELEmekQKDRELSQTLENEKNALLTQISAKDSELkllEEEVAK-INMLNQQIQEELS- 1883
Cdd:TIGR01612 1013 -----KENMLYHQFDEKEKATNDIE---QKIEDANKNIPNIEIAIHTSIYNIIDEI---EKEIGKnIELLNKEILEEAEi 1081

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1884 RVTKLKETAEEEK----DDLEE----RLMNQLAELNGSIGNYYQDVtDAQIKN-EQLESEMQNLkrcvseLEEEKQQLVK 1954
Cdd:TIGR01612 1082 NITNFNEIKEKLKhynfDDFGKeeniKYADEINKIKDDIKNLDQKI-DHHIKAlEEIKKKSENY------IDEIKAQIND 1154

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1955 EKTKVESEIRKEYMEKIQGAQKGPGSKIHAKE-LQELLKEKQQEVKQLQKDcirylgrISALEKtVKALEFVHTESQKDL 2033
Cdd:TIGR01612 1155 LEDVADKAISNDDPEEIEKKIENIVTKIDKKKnIYDEIKKLLNEIAEIEKD-------KTSLEE-VKGINLSYGKNLGKL 1226

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2034 datkgNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRK 2113
Cdd:TIGR01612 1227 -----FLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENIS 1301

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2114 EKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLdSTLAQLAAFTKsmsslQDDRDRVIDEAKKWEQRFG 2193
Cdd:TIGR01612 1302 DIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYL-NEIANIYNILK-----LNKIKKIIDEVKEYTKEIE 1375

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2194 DAIQTKEEEVRLKEENCTALKDQlrqmtIHMEELKITVSRLEHDKEIWES-KAQTELQH-------QQKAYDKLQEENKE 2265
Cdd:TIGR01612 1376 ENNKNIKDELDKSEKLIKKIKDD-----INLEECKSKIESTLDDKDIDECiKKIKELKNhilseesNIDTYFKNADENNE 1450

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2266 LMSQLEEAGQLYHDSKNELTKLE------------SELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNC--KF 2331
Cdd:TIGR01612 1451 NVLLLFKNIEMADNKSQHILKIKkdnatndhdfniNELKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELlnKY 1530

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2332 NCEQLETDLTASRELTTRLHDEINVKEQKIIsLLSGKEEaiqvaiaelhqqhsKEIKELENLLSQEEEENLTLEEENKRA 2411
Cdd:TIGR01612 1531 SALAIKNKFAKTKKDSEIIIKEIKDAHKKFI-LEAEKSE--------------QKIKEIKKEKFRIEDDAAKNDKSNKAA 1595

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2412 VEKTNQLtEALET-------IKKESLEQKAQLDSFVKSMSSLQDDRdrivsdyrqlEERHLSVILEKDELIQDAAAENNK 2484
Cdd:TIGR01612 1596 IDIQLSL-ENFENkflkisdIKKKINDCLKETESIEKKISSFSIDS----------QDTELKENGDNLNSLQEFLESLKD 1664

                         1130      1140      1150      1160      1170      1180
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564376925  2485 LKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVITIKDSQQRQLLEAQLQQNKELRNECVK 2548
Cdd:TIGR01612 1665 QKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKELIEPTIE 1728
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1986-2598 4.17e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 4.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1986 ELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEfvhtESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLDDTQ 2065
Cdd:PRK03918  190 NIEELIKEKEKELEEVLREINEISSELPELREELEKLE----KEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELE 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2066 SEAArvladnlKLKKELQSNKESIKSQIK-QKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEDTLAEiqvsLT 2144
Cdd:PRK03918  266 ERIE-------ELKKEIEELEEKVKELKElKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKE----LE 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2145 RKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRdRVIDEAKKWEQRFG-----------DAIQTKEEEVRLKEENCTAL 2213
Cdd:PRK03918  335 EKEERLEELKKKLKELEKRLEELEERHELYEEAK-AKKEELERLKKRLTgltpeklekelEELEKAKEEIEEEISKITAR 413

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2214 KDQLRQmtiHMEELKITVSRLEHDKEIWE-SKAQTELQHQQKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLESELK 2292
Cdd:PRK03918  414 IGELKK---EIKELKKAIEELKKAKGKCPvCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLK 490

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2293 SLKDQSTdLKNSLEKCREHENNLEgiikqqeadiqncKFNCEQLETDLTASRELttrlhdeinvkeqkiisllsgKEEAI 2372
Cdd:PRK03918  491 KESELIK-LKELAEQLKELEEKLK-------------KYNLEELEKKAEEYEKL---------------------KEKLI 535

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2373 QVaiaelhqqhSKEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDR 2452
Cdd:PRK03918  536 KL---------KGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLE 606

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2453 IVSDYRQLEERHLSVILEKDELiQDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRrdlneviTIKDSQQRQLL 2532
Cdd:PRK03918  607 LKDAEKELEREEKELKKLEEEL-DKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREE-------YLELSRELAGL 678

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564376925 2533 EAQLQQNKELRNECVKLEGRLKGSEAEKQSLQMSLDALQ---EENQGLSKEIKSFKeqltALHEEGALA 2598
Cdd:PRK03918  679 RAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEkalERVEELREKVKKYK----ALLKERALS 743
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1149-1620 4.46e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.27  E-value: 4.46e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1149 ELEGKIVDLEKEKTQLQKKLQEAlisrKAILKKAQEKekhlKEELKEQKDAYRHLQEQFDGQSKENENIAARLRQLQAKE 1228
Cdd:PRK02224  217 ELDEEIERYEEQREQARETRDEA----DEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1229 ST-----DQQLPGTGQQEPTHGS-----EGLSLEGTEPASESDLHAAQPSHPGETATlQATVSVAQIQDQLKEIEVEKEE 1298
Cdd:PRK02224  289 EEleeerDDLLAEAGLDDADAEAvearrEELEDRDEELRDRLEECRVAAQAHNEEAE-SLREDADDLEERAEELREEAAE 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1299 LELKISSTTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIADLE-HLKTLQPELETLQK 1377
Cdd:PRK02224  368 LESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTARERVEEAEA 447

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1378 ------------------HV---GQKEEEVSYLVGQLGEKEQTLTTVQTEME------EQERLIKALHTQLEMQAK---E 1427
Cdd:PRK02224  448 lleagkcpecgqpvegspHVetiEEDRERVEELEAELEDLEEEVEEVEERLEraedlvEAEDRIERLEERREDLEEliaE 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1428 HEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSLADVE---SQ 1504
Cdd:PRK02224  528 RRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIAdaeDE 607

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1505 VSVQNQEKDALLG-------KLALLQEERDKLIVEMDKSLLEN-----QSLGGSCESLKLALGGLTEDKEKLMKELESVR 1572
Cdd:PRK02224  608 IERLREKREALAElnderreRLAEKRERKRELEAEFDEARIEEaredkERAEEYLEQVEEKLDELREERDDLQAEIGAVE 687

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 564376925 1573 cSKIAESTEWQEKHKELQKEYEVLlqsyENVSNEAERIQHVVESVRQE 1620
Cdd:PRK02224  688 -NELEELEELRERREALENRVEAL----EALYDEAEELESMYGDLRAE 730
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1360-1572 5.02e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 5.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1360 ADLEHLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKAlhtqLEMQAKEHEERLKQVQVEI 1439
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA----LEQELAALEAELAELEKEI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1440 CELKKQPKELEEE-----SKAKQQLQRKLQAALISRKEALKENKSLQ--EQLSSAR-DAVEHLTKSLADVESQVSVQNQE 1511
Cdd:COG4942    93 AELRAELEAQKEElaellRALYRLGRQPPLALLLSPEDFLDAVRRLQylKYLAPARrEQAEELRADLAELAALRAELEAE 172

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564376925 1512 KDALLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESVR 1572
Cdd:COG4942   173 RAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
PRK11281 PRK11281
mechanosensitive channel MscK;
161-435 5.49e-05

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 49.14  E-value: 5.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  161 LQAQLDQAQS-EQASQLDK-SSAEMEDFVLMRQKLQEKEELIGALQTQLSQTQAEQA---AQLSSMQqvvreKDARFETQ 235
Cdd:PRK11281   41 VQAQLDALNKqKLLEAEDKlVQQDLEQTLALLDKIDRQKEETEQLKQQLAQAPAKLRqaqAELEALK-----DDNDEETR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  236 VRLHEDELLQLVTQSdveTEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQR----NQDLSQQLQLLEAEHST 311
Cdd:PRK11281  116 ETLSTLSLRQLESRL---AQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRlqqiRNLLKGGKVGGKALRPS 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  312 LRNTMEAERQ--ESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQygTLQqrheTEMEEKTACISllQKNEQE 389
Cdd:PRK11281  193 QRVLLQAEQAllNAQNDLQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQ--LLQ----EAINSKRLTLS--EKTVQE 264

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 564376925  390 LQSACDALKEENSKLLQEQQEQAAKSAQAL-QQLE--DELQQKSKEISQ 435
Cdd:PRK11281  265 AQSQDEAARIQANPLVAQELEINLQLSQRLlKATEklNTLTQQNLRVKN 313
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1330-1749 5.68e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 5.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1330 EIQNLKAASHEAKAHTEQLKQELESSQLKIADLEHLKTLQPELETLQKHVGQKEEEVSYLvGQLGEKEQTLTTVQTEMEE 1409
Cdd:COG4717    89 EYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERL-EELEERLEELRELEEELEE 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1410 QERLIKALHTQLEMQAK----EHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAA---LISRKEALKENKSLQE 1482
Cdd:COG4717   168 LEAELAELQEELEELLEqlslATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEleqLENELEAAALEERLKE 247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1483 QLSSARDAVEHLTKSLADVESQVSVQNQEKDALLG-------------KLALLQEERDKLIVEMDKSLLENQSLGGSCES 1549
Cdd:COG4717   248 ARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVlgllallflllarEKASLGKEAEELQALPALEELEEEELEELLAA 327

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1550 LKLALGGLTEDKEKLMKELESVRCS-KIAESTEWQEKHKELQKEYEVLLQSYeNVSNEAERIQHVVESvrQEKQEVYAKL 1628
Cdd:COG4717   328 LGLPPDLSPEELLELLDRIEELQELlREAEELEEELQLEELEQEIAALLAEA-GVEDEEELRAALEQA--EEYQELKEEL 404

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1629 RSAESDKREREKQLQDAEQEMEEMKEKMRkfAKSKQQKILELEEENDRLRAEaqpVGGANESMEALLSSN--ASLKEELE 1706
Cdd:COG4717   405 EELEEQLEELLGELEELLEALDEEELEEE--LEELEEELEELEEELEELREE---LAELEAELEQLEEDGelAELLQELE 479

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 564376925 1707 RITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQELKQAS 1749
Cdd:COG4717   480 ELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1574-2329 6.95e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.07  E-value: 6.95e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1574 SKIAESTEWQEKHKELQKEYEVLLQSYEnvsneaERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMK 1653
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTLD------DQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETA 342

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1654 EKMRKFAKSKQQKILELEEENDRLRAEAQPVGGANESMEALLSSN-----ASLKEELERITLEYKTLSKEFEA------- 1721
Cdd:pfam12128  343 AADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnnrdiAGIKDKLAKIREARDRQLAVAEDdlqales 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1722 -----LMAEKNTLSEETRNLKLQVEAQELKQASLETTEksdEPKDVIEEVTEAVVGKSQEQDSlsENAKLEDAEATLLAn 1796
Cdd:pfam12128  423 elreqLEAGKLEFNEEEYRLKSRLGELKLRLNQATATP---ELLLQLENFDERIERAREEQEA--ANAEVERLQSELRQ- 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1797 sAKPGVSETFSSHDDINNYLQQLdqlKGRIAELE-MEKQKDRELSQTLENE------------KNALL---------TQI 1854
Cdd:pfam12128  497 -ARKRRDQASEALRQASRRLEER---QSALDELElQLFPQAGTLLHFLRKEapdweqsigkviSPELLhrtdldpevWDG 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1855 SAKDS------ELKLLEEEVAKINMLNQQIQEELSRVtklkETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQ--I 1926
Cdd:pfam12128  573 SVGGElnlygvKLDLKRIDVPEWAASEEELRERLDKA----EEALQSAREKQAAAEEQLVQANGELEKASREETFARtaL 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1927 KN-----EQLESEMQNLKR-CVSELEEEKQQLVKEKTKVESEirkeymekiqgaqkgpgskihakelQELLKEKQQEVKQ 2000
Cdd:pfam12128  649 KNarldlRRLFDEKQSEKDkKNKALAERKDSANERLNSLEAQ-------------------------LKQLDKKHQAWLE 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2001 LQKDcirylgriSALEKTVKALEFVHtESQKDLDATKGNLAQAVEhhkkaqAELSSFKILLDDTQSEAARVLAdNLKLKK 2080
Cdd:pfam12128  704 EQKE--------QKREARTEKQAYWQ-VVEGALDAQLALLKAAIA------ARRSGAKAELKALETWYKRDLA-SLGVDP 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2081 ELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMK----ELQQS 2156
Cdd:pfam12128  768 DVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKlrraKLEME 847

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2157 LDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWEqrfgdaiqtkEEEVRLKEENCTALKDQLRQmtIHMEELKITVSRLEH 2236
Cdd:pfam12128  848 RKASEKQQVRLSENLRGLRCEMSKLATLKEDAN----------SEQAQGSIGERLAQLEDLKL--KRDYLSESVKKYVEH 915

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2237 DKEIWESKAQTEL-QHQQKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNL 2315
Cdd:pfam12128  916 FKNVIADHSGSGLaETWESLREEDHYQNDKGIRLLDYRKLVPYLEQWFDVRVPQSIMVLREQVSILGVDLTEFYDVLADF 995

                          810
                   ....*....|....
gi 564376925  2316 EGIIKQQEADIQNC 2329
Cdd:pfam12128  996 DRRIASFSRELQRE 1009
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1984-2191 7.48e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 7.48e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1984 AKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLDD 2063
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2064 TQSEAARVLA--------DNLKLKKELQSNKESIKS-----QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKA 2130
Cdd:COG4942   102 QKEELAELLRalyrlgrqPPLALLLSPEDFLDAVRRlqylkYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564376925 2131 HVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWEQR 2191
Cdd:COG4942   182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 153-425 7.64e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 48.68  E-value: 7.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  153 EKEKLISNLQAQLDQAQSEQASQLDKSSAEMEdfvlmRQKL-QEKEELIGALQTqlSQTQAEQAAQLSSMQQVVREKDAr 231
Cdd:NF012221 1539 ESSQQADAVSKHAKQDDAAQNALADKERAEAD-----RQRLeQEKQQQLAAISG--SQSQLESTDQNALETNGQAQRDA- 1610

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  232 FETQVRLHEDELLQLVTQSDV-ETEVQQKLRVMQRKLEEHEEALLGRAQvVDLLQKELTSAEQRNQdlsqqlqlleaehs 310
Cdd:NF012221 1611 ILEESRAVTKELTTLAQGLDAlDSQATYAGESGDQWRNPFAGGLLDRVQ-EQLDDAKKISGKQLAD-------------- 1675

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  311 tLRNTMEAERQESKILMEKVELEMAERkeelYQLQGQLERAG-QAQAELEMQYG-TLQQRHETEMEEKTACISLlqkneQ 388
Cdd:NF012221 1676 -AKQRHVDNQQKVKDAVAKSEAGVAQG----EQNQANAEQDIdDAKADAEKRKDdALAKQNEAQQAESDANAAA-----N 1745

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 564376925  389 ELQSAcdalKEENSKLLQEQQEQAAKSAQALQQLEDE 425
Cdd:NF012221 1746 DAQSR----GEQDASAAENKANQAQADAKGAKQDESD 1778
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1441-2159 8.44e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.48  E-value: 8.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1441 ELKKQPKELEEESKAKQQLQRKLQAALISRKEALK-----------ENKSLQEQLSSARDAVEHLTKSLADVESQVSVQN 1509
Cdd:TIGR04523   37 QLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINnsnnkikileqQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDK 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1510 QEKDALLGKLALLQEERDKLIVEMDKSLLEnqslggsCESLKLALGGLTEDKEKLMKELESVRCSKIAESTEWQEKHKEL 1589
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTE-------IKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1590 QKeyevllqsyenvSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILE 1669
Cdd:TIGR04523  190 DK------------IKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQ 257

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1670 LEEENDRLraeaqpvgganesmeallssnaslKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQELKQAS 1749
Cdd:TIGR04523  258 LKDEQNKI------------------------KKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELK 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1750 LETTEKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKledaeatllansakpgvsETFSSHDDINNYLQQLDQLKGRIAEL 1829
Cdd:TIGR04523  314 SELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKK------------------ELTNSESENSEKQRELEEKQNEIEKL 375

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1830 EMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEerlmNQLAE 1909
Cdd:TIGR04523  376 KKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLT----NQDSV 451

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1910 LNGSIGNYyqdvtdaQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKgpgskihAKELQE 1989
Cdd:TIGR04523  452 KELIIKNL-------DNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEK-------VKDLTK 517

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1990 LLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFvhtesqkdlDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAA 2069
Cdd:TIGR04523  518 KISSLKEKIEKLESEKKEKESKISDLEDELNKDDF---------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ 588

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2070 rvladnlKLKKELQSNKESIKSQIKQKD---EDLLRRLEQAEEKHRK---EKKNMQEKLDALHREKAHVEDTLAEIQVSL 2143
Cdd:TIGR04523  589 -------ELIDQKEKEKKDLIKEIEEKEkkiSSLEKELEKAKKENEKlssIIKNIKSKKNKLKQEVKQIKETIKEIRNKW 661

                          730
                   ....*....|....*.
gi 564376925  2144 TRKDKDMKELQQSLDS 2159
Cdd:TIGR04523  662 PEIIKKIKESKTKIDD 677
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1817-1970 1.07e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.46  E-value: 1.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1817 QQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKE------ 1890
Cdd:COG1579    17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1891 ---TAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEY 1967
Cdd:COG1579    97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                  ...
gi 564376925 1968 MEK 1970
Cdd:COG1579   177 LAL 179
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 678-1369 1.09e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 1.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   678 LERLKTQVLELETSLHTAKETHEKN--------------LSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLly 743
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELHEKQkfylrqsvidlqtkLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAA-- 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   744 RVKELDVLGELRAQVRELETSLAEAE----KQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIETLQRELDgvqLQFS 819
Cdd:pfam15921  158 KCLKEDMLEDSNTQIEQLRKMMLSHEgvlqEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELD---TEIS 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   820 EQGTQIRSLQSQLQTKESEVLEGAERMkdISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQ---QTIQEKDQ--- 893
Cdd:pfam15921  235 YLKGRIFPVEDQLEALKSESQNKIELL--LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQsqlEIIQEQARnqn 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   894 -----QVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLSL----LSRAEGAKKEQVEDSG------------------- 945
Cdd:pfam15921  313 smymrQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLanseLTEARTERDQFSQESGnlddqlqklladlhkreke 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   946 --AESSPKHGPHESSAQEPVCKDALQQELE--------------WLRKESEQRKRKLQAALISRKELLQKVSKLEEELak 1009
Cdd:pfam15921  393 lsLEKEQNKRLWDRDTGNSITIDHLRRELDdrnmevqrleallkAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQL-- 470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1010 vreESTKDSLRE------SEKRELEEDSKNKDDPEKYGTSEWRELEVS------LRLTISEKEVELEGIRRDLKEKAAAE 1077
Cdd:pfam15921  471 ---ESTKEMLRKvveeltAKKMTLESSERTVSDLTASLQEKERAIEATnaeitkLRSRVDLKLQELQHLKNEGDHLRNVQ 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1078 EELQALVQRMTQdlqnKTKQIDLLQEEItENQATIQKFITGTMDAGDGDSAVKETSVSSppRAGGGEHWK---------- 1147
Cdd:pfam15921  548 TECEALKLQMAE----KDKVIEILRQQI-ENMTQLVGQHGRTAGAMQVEKAQLEKEIND--RRLELQEFKilkdkkdaki 620

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1148 PELEGKIVDLEKEKTQLQKKLQEALisrKAILKKAQEKEKHLKE------ELKEQKDAYRHLQEQFDGQSKENENIAARL 1221
Cdd:pfam15921  621 RELEARVSDLELEKVKLVNAGSERL---RAVKDIKQERDQLLNEvktsrnELNSLSEDYEVLKRNFRNKSEEMETTTNKL 697

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1222 R-QLQAKESTDQQLPGTgqQEPTHGSEGLSLEgtepaSESDLHAAQPSHPGETATLQATV-----SVAQIQDQLKEIEVE 1295
Cdd:pfam15921  698 KmQLKSAQSELEQTRNT--LKSMEGSDGHAMK-----VAMGMQKQITAKRGQIDALQSKIqfleeAMTNANKEKHFLKEE 770

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564376925  1296 KEELELKISSTTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQL-----KQELESSQLKIADLEHLKTLQ 1369
Cdd:pfam15921  771 KNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECqdiiqRQEQESVRLKLQHTLDVKELQ 849
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2250-2929 1.31e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.81  E-value: 1.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2250 QHQQKAYDKLQEENKELMSQLEEAGQLYhdskneltklESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNC 2329
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELH----------EKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDL 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2330 KFNCEQLETDLTASRELTTRLHDEINVKEQKIISLLSGKE---EAIQVAIAELHQQHSKEIKELENLLSQEEEENLTLEE 2406
Cdd:pfam15921  144 RNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAIS 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2407 ENKRAVE--------KTNQLTEALETIKKESLEQKAQLdsfvksmssLQDDRDRIvsdyRQLEERHLSVILEKDELIQDA 2478
Cdd:pfam15921  224 KILRELDteisylkgRIFPVEDQLEALKSESQNKIELL---------LQQHQDRI----EQLISEHEVEITGLTEKASSA 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2479 AAENNKLKEEIRGLRGHMDDLNS----ENAKLDAELIQYRRDLNEVITIKDSQQRQLLEAQLQQNKELRNECVKLEGRLK 2554
Cdd:pfam15921  291 RSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQ 370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2555 GSEAEKQSLQMSLDALQEENQGLSKEiKSFKEQLTALHEEGALAVYH--AQLRVREEEVQKLTA---ALSSSQKRTVDLQ 2629
Cdd:pfam15921  371 ESGNLDDQLQKLLADLHKREKELSLE-KEQNKRLWDRDTGNSITIDHlrRELDDRNMEVQRLEAllkAMKSECQGQMERQ 449

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2630 EELVCVQKEASKKVSEIEDKLkrelkhlhhnagimrnetETAEERVAELARDLVEMEQKLLTVTKENKDLTAQIQAFGKS 2709
Cdd:pfam15921  450 MAAIQGKNESLEKVSSLTAQL------------------ESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERA 511

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2710 MSSlqdsrdhATEELSDLKKKYDASLKELAQLKGRQDLGResdvlsqaafplttseNISSRLEKLNQQLTSKDEQLLHLS 2789
Cdd:pfam15921  512 IEA-------TNAEITKLRSRVDLKLQELQHLKNEGDHLR----------------NVQTECEALKLQMAEKDKVIEILR 568

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2790 SELESSHNQVQSFTKAMTSLQNERDHLWN-------ELEKFRKSEEGKQ-RSAAPSAASSPAEVQSLK---------KAM 2852
Cdd:pfam15921  569 QQIENMTQLVGQHGRTAGAMQVEKAQLEKeindrrlELQEFKILKDKKDaKIRELEARVSDLELEKVKlvnagserlRAV 648

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925  2853 SSLQNDRDRLLKELKNLQQQYLQMNQEITELRplkaqlQESQDQTKALQMMKEELRQENLSWQHELHQLRVEKNSWE 2929
Cdd:pfam15921  649 KDIKQERDQLLNEVKTSRNELNSLSEDYEVLK------RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSME 719
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1842-2159 1.58e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.61  E-value: 1.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1842 TLENEKNALLTqisakdselKLLEEEVAKINMLNQQIQ-EELSRVTKLKETAEEEKDdleerLMNQLAELNGSIgnyyqd 1920
Cdd:PRK05771   13 TLKSYKDEVLE---------ALHELGVVHIEDLKEELSnERLRKLRSLLTKLSEALD-----KLRSYLPKLNPL------ 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1921 vtdaqikneqlESEMQNLKrcVSELEEEKQQLVKEKTKVESEIrKEYMEKIqgaqkgpgskihaKELQELLKEKQQEVKQ 2000
Cdd:PRK05771   73 -----------REEKKKVS--VKSLEELIKDVEEELEKIEKEI-KELEEEI-------------SELENEIKELEQEIER 125

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2001 LQ---------------KDCIRYLGRISA-------LEKTVKALEFVHTESQKDLDAtkgnLAQAVEHHKKAQAELSSFk 2058
Cdd:PRK05771  126 LEpwgnfdldlslllgfKYVSVFVGTVPEdkleelkLESDVENVEYISTDKGYVYVV----VVVLKELSDEVEEELKKL- 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2059 illddtqsEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhREKAHVEDTLAE 2138
Cdd:PRK05771  201 --------GFERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIE-LERAEALSKFLK 271

                         330       340       350
                  ....*....|....*....|....*....|
gi 564376925 2139 iqvslTRK---------DKDMKELQQSLDS 2159
Cdd:PRK05771  272 -----TDKtfaiegwvpEDRVKKLKELIDK 296
46 PHA02562
endonuclease subunit; Provisional
 1812-1970 1.75e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.32  E-value: 1.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1812 INNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKL-------------LEEEVAKINMLNQQI 1878
Cdd:PHA02562  229 AKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMyekggvcptctqqISEGPDRITKIKDKL 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1879 QEELSRVTKLKETAEEEKDDLEERLMNQ--LAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEK 1956
Cdd:PHA02562  309 KELQHSLEKLDTAIDELEEIMDEFNEQSkkLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDEL 388

                         170
                  ....*....|....
gi 564376925 1957 TKVESEIRKEYMEK 1970
Cdd:PHA02562  389 DKIVKTKSELVKEK 402
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1149-1627 1.86e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.32  E-value: 1.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1149 ELEGKIVDLEKEKTQLQK---KLQEALISRKAILKKAQEKEKHLKEELKEQKDAYRHLQEQFDGQSKENENIAARLRQLQ 1225
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDnieKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1226 AKESTDQQlpgtgqqeptHGSEGLSLEGTEPASESDLHAAQPshpgETATLQATVSVAQIQDQLKEIEVEKEELELKISS 1305
Cdd:TIGR04523  295 SEISDLNN----------QKEQDWNKELKSELKNQEKKLEEI----QNQISQNNKIISQLNEQISQLKKELTNSESENSE 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1306 TTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIadlehlKTLQPELETLQKHVGQKEEE 1385
Cdd:TIGR04523  361 KQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQI------KKLQQEKELLEKEIERLKET 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1386 VSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHEERLKQVQVEICELKKQPKELEEESKAKQQLQrklqa 1465
Cdd:TIGR04523  435 IIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELE----- 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1466 alisrkealKENKSLQEQLSSARDAVEHLTKSLADVESQVSVQNQE--KDALLGKLALLQEERDKLIVEMDKSLLENQSL 1543
Cdd:TIGR04523  510 ---------EKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDElnKDDFELKKENLEKEIDEKNKEIEELKQTQKSL 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1544 GGSCESLKLALGGLTEDKEKLMKELEsvrcSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQE 1623
Cdd:TIGR04523  581 KKKQEEKQELIDQKEKEKKDLIKEIE----EKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656


                   ....
gi 564376925  1624 VYAK 1627
Cdd:TIGR04523  657 IRNK 660
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 804-1533 1.89e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 47.35  E-value: 1.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   804 IETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDIskemEELSQALSQKELEIAQMDQLLLEKKKDVET 883
Cdd:TIGR00606  212 LKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEI----EHNLSKIMKLDNEIKALKSRKKQMEKDNSE 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   884 LQQTIQE----KDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLSLLSRaEGAKKEQVEDSGAESSPKHGPHESSA 959
Cdd:TIGR00606  288 LELKMEKvfqgTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQ-EKTELLVEQGRLQLQADRHQEHIRAR 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   960 QEPVCKDALQQELEW----------------LRKESEQRKRKLQAALISrkELLQKVSKLEEELAKVREESTKDSLRESE 1023
Cdd:TIGR00606  367 DSLIQSLATRLELDGfergpfserqiknfhtLVIERQEDEAKTAAQLCA--DLQSKERLKQEQADEIRDEKKGLGRTIEL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1024 KRELEEDSKNKddpEKYGTSEWRELEVSLRlTISEKEVELEGIRRDLK--EKAAAEEELQALV---QRMTQDLQNKTKQI 1098
Cdd:TIGR00606  445 KKEILEKKQEE---LKFVIKELQQLEGSSD-RILELDQELRKAERELSkaEKNSLTETLKKEVkslQNEKADLDRKLRKL 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1099 DLLQEEITENQATIQKFITGTMDAGDGDSAVKETSVSSPPR---AGGGEHWKPELEGKIVDLEKEKTQLQKKLQEALISr 1175
Cdd:TIGR00606  521 DQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDEltsLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKE- 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1176 kaiLKKAQEKEKHLKEELKEQKDAYRHLQEQ-FDGQSKENENIA-ARLRQLQAKESTDQQLPGTGQQEPTHGSEGLSLE- 1252
Cdd:TIGR00606  600 ---LASLEQNKNHINNELESKEEQLSSYEDKlFDVCGSQDEESDlERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDEn 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1253 -GTEPASESDLHAAQP----SHPGETATLQATVSVAQIQDQLKEIEVEKEELELKISSTTSELTKKSEEVLLLQEQINEQ 1327
Cdd:TIGR00606  677 qSCCPVCQRVFQTEAElqefISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKV 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1328 GLEIQNLKAASHEAKAHTEQLKQELESSQLKIADLEHLKTLQPELETLQKHVGQKEEEVSYLVGQLgekeqTLTTVQTEM 1407
Cdd:TIGR00606  757 NRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDR-----TVQQVNQEK 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1408 EEQERLIKALHTQLEMQAKEHEERLKQVQV---EICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQL 1484
Cdd:TIGR00606  832 QEKQHELDTVVSKIELNRKLIQDQQEQIQHlksKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQD 911

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 564376925  1485 SSARDAVEhltKSLADVESQVSVQNQEKDALLGKLALLQEERDKLIVEM 1533
Cdd:TIGR00606  912 SPLETFLE---KDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYM 957
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1578-2155 1.91e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.27  E-value: 1.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1578 ESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMR 1657
Cdd:TIGR00618  270 EELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1658 KFAKSKQQKI-----LELEEENDRLRAEAQPVGGANESMEALLSSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEE 1732
Cdd:TIGR00618  350 LHSQEIHIRDahevaTSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHA 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1733 TRNLKLQVEAQELKQASLETTEKSDEPKDV----IEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKPGVSETFSS 1808
Cdd:TIGR00618  430 KKQQELQQRYAELCAAAITCTAQCEKLEKIhlqeSAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGS 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1809 HDDINNYLQQLDQLKG---RIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRV 1885
Cdd:TIGR00618  510 CIHPNPARQDIDNPGPltrRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1886 TKLKETAE-------EEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEM---QNLKRCVSELEEEKQQLVKE 1955
Cdd:TIGR00618  590 QNITVRLQdlteklsEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTalhALQLTLTQERVREHALSIRV 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1956 KTKVESEIRKEYMEKIQG-AQKGPGSKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLD 2034
Cdd:TIGR00618  670 LPKELLASRQLALQKMQSeKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELM 749

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2035 ATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKE 2114
Cdd:TIGR00618  750 HQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQE 829

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 564376925  2115 KKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQ 2155
Cdd:TIGR00618  830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAK 870
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 677-1105 2.19e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.04  E-value: 2.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   677 ELERLKTQVLELETSLHTAKETHEKNLSEKAKEISSltqltkefkesaeeARSTLTAVCEERDQLLYRVKELDvlgelrA 756
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVL--------------ANSELTEARTERDQFSQESGNLD------D 377

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   757 QVRELETSLAEAEKQRGLDyesqraqhnllTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKE 836
Cdd:pfam15921  378 QLQKLLADLHKREKELSLE-----------KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   837 SEVL-------EGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTIQEKDQ-------QVTELSFSM 902
Cdd:pfam15921  447 ERQMaaiqgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERaieatnaEITKLRSRV 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   903 TEKMVQLNEEKF------SLGVEIKTLKEQLSLLSRAEGAKKEQVEDsgaeSSPKHGPHESSAqepvckDALQQELEWLR 976
Cdd:pfam15921  527 DLKLQELQHLKNegdhlrNVQTECEALKLQMAEKDKVIEILRQQIEN----MTQLVGQHGRTA------GAMQVEKAQLE 596

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   977 KESEQRKRKLQAALISR-------KELLQKVSKLEEELAKV------REESTKDSLRESE---------KRELEEDSKNK 1034
Cdd:pfam15921  597 KEINDRRLELQEFKILKdkkdakiRELEARVSDLELEKVKLvnagseRLRAVKDIKQERDqllnevktsRNELNSLSEDY 676

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564376925  1035 DDPEKYGTSEWRELEVS---LRLTISEKEVELEGIRRDLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEEI 1105
Cdd:pfam15921  677 EVLKRNFRNKSEEMETTtnkLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI 750
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1697-2325 2.36e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.04  E-value: 2.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1697 SNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEA--QELKQASLETTEKSDepKDVIEEVTEAVVGKS 1774
Cdd:pfam15921  139 SQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGvlQEIRSILVDFEEASG--KKIYEHDSMSTMHFR 216

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1775 QEQDSLSENAKLEDAEATLLANSAKPGVSE----TFSSHDDINNYLQQ-LDQLKGRIAELEMEKQKDRELSQTLENEKNA 1849
Cdd:pfam15921  217 SLGSAISKILRELDTEISYLKGRIFPVEDQlealKSESQNKIELLLQQhQDRIEQLISEHEVEITGLTEKASSARSQANS 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1850 LltqisakDSELKLLEEEVAKIN-MLNQQIQEELSRVTKLKETAEEEKDDLEERLmnqlAELNGSIGNYYQDVTDAQIKN 1928
Cdd:pfam15921  297 I-------QSQLEIIQEQARNQNsMYMRQLSDLESTVSQLRSELREAKRMYEDKI----EELEKQLVLANSELTEARTER 365

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1929 EQLESEMQNLkrcvselEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPGSKIHAKELQELLKEKQQEV-------KQL 2001
Cdd:pfam15921  366 DQFSQESGNL-------DDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVqrleallKAM 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2002 QKDCIRYLGR-ISALEKTVKALEFVHTESQKdLDATKGNLAQAVEHHKKAQAELSSFKILLDD--------------TQS 2066
Cdd:pfam15921  439 KSECQGQMERqMAAIQGKNESLEKVSSLTAQ-LESTKEMLRKVVEELTAKKMTLESSERTVSDltaslqekeraieaTNA 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2067 EAARVLAD-NLKLK------------KELQSNKESIKSQIKQKDE--DLLRR----LEQAEEKHRKEKKNMQEKLDALHR 2127
Cdd:pfam15921  518 EITKLRSRvDLKLQelqhlknegdhlRNVQTECEALKLQMAEKDKviEILRQqienMTQLVGQHGRTAGAMQVEKAQLEK 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2128 EKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSslqdDRDRVIDEAKKWEQRFGDAIQTKEEEVRLKE 2207
Cdd:pfam15921  598 EINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGS----ERLRAVKDIKQERDQLLNEVKTSRNELNSLS 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2208 ENCTALKDQLRQMTIHME--------ELKITVSRLEHDKEIWESKA-------------QTELQHQQKAYDKLQEENKEL 2266
Cdd:pfam15921  674 EDYEVLKRNFRNKSEEMEtttnklkmQLKSAQSELEQTRNTLKSMEgsdghamkvamgmQKQITAKRGQIDALQSKIQFL 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2267 MSQLEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNL---------------------EGIIKQQEAD 2325
Cdd:pfam15921  754 EEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLkekvanmevaldkaslqfaecQDIIQRQEQE 833
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
46-433 2.38e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.96  E-value: 2.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   46 QKDVLDRLADAEKLVLELKDIISKQDAQLQQKDEALQEekkgaeskikkiklhAKAKITSLNKQIEELktqggaasppEV 125
Cdd:PRK02224  201 EKDLHERLNGLESELAELDEEIERYEEQREQARETRDE---------------ADEVLEEHEERREEL----------ET 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  126 QAEELSKHDKSSTEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEqasqLDKSSAEMEDFVLMRQKLQ-EKEELIGALQ 204
Cdd:PRK02224  256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAE----AGLDDADAEAVEARREELEdRDEELRDRLE 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  205 TQLSQTQA---------EQAAQLSSMQQVVREKDARFETQVrlhEDELLQLVTQSDVETEVQQKLRVMQRKLEEHEEALL 275
Cdd:PRK02224  332 ECRVAAQAhneeaeslrEDADDLEERAEELREEAAELESEL---EEAREAVEDRREEIEELEEEIEELRERFGDAPVDLG 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  276 GRAQVVDLLQKELTSAEQRnqdlsqqLQLLEAEHSTLRNTMEAERQ------------------------ESKILMEKVE 331
Cdd:PRK02224  409 NAEDFLEELREERDELRER-------EAELEATLRTARERVEEAEAlleagkcpecgqpvegsphvetieEDRERVEELE 481

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  332 LEMAERKEELYQLQGQLERAGQAqAELEMQYGTLQQR----------HETEMEEKTACISLLQKNEQELQSACDALKEEn 401
Cdd:PRK02224  482 AELEDLEEEVEEVEERLERAEDL-VEAEDRIERLEERredleeliaeRRETIEEKRERAEELRERAAELEAEAEEKREA- 559

                         410       420       430
                  ....*....|....*....|....*....|..
gi 564376925  402 sklLQEQQEQAAKSAQALQQLEDELQQKSKEI 433
Cdd:PRK02224  560 ---AAEAEEEAEEAREEVAELNSKLAELKERI 588
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2096-2936 2.41e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.96  E-value: 2.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2096 KDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQ 2175
Cdd:TIGR00606  186 KALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIM 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2176 --DDRDRVIDEAKKWEQRFGDAIQTKEEEVRLKEENCTALKDQLRQMTIHMEELKitvsRLEHDKEIWESKAQTELQHQQ 2253
Cdd:TIGR00606  266 klDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERE----LVDCQRELEKLNKERRLLNQE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2254 KAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLESELKSLKDQStdlknslEKCREHENNLEGIIKQQEADIQNCKFNC 2333
Cdd:TIGR00606  342 KTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGP-------FSERQIKNFHTLVIERQEDEAKTAAQLC 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2334 EQLETDLTASRELTTRLHDEinvkeqkiislLSGKEEAIQVAIAELhqqhSKEIKELENLLSQEEEENLTLeeenKRAVE 2413
Cdd:TIGR00606  415 ADLQSKERLKQEQADEIRDE-----------KKGLGRTIELKKEIL----EKKQEELKFVIKELQQLEGSS----DRILE 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2414 KTNQLTEALETIKKesLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSVILEKDELIQDAAAENNKLK--EEIRG 2491
Cdd:TIGR00606  476 LDQELRKAERELSK--AEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDkdEQIRK 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2492 LRG-HMDDLNSE------NAKLDAELIQYRRDLNevITIKDSQQRQLLEAQLQQNK-ELRNECVKLEGRLKGSEaEKQSL 2563
Cdd:TIGR00606  554 IKSrHSDELTSLlgyfpnKKQLEDWLHSKSKEIN--QTRDRLAKLNKELASLEQNKnHINNELESKEEQLSSYE-DKLFD 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2564 QMSLDALQEENQGLSKEIKSFKEQLTALheEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKV 2643
Cdd:TIGR00606  631 VCGSQDEESDLERLKEEIEKSSKQRAML--AGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAP 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2644 SEIEDkLKRELKHLHHNAGIMRNETETAEERVAELARDLVEMEQKLLTVTKE----NKDLTAQIQAFGKSMSSLQDSRDH 2719
Cdd:TIGR00606  709 DKLKS-TESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDiqrlKNDIEEQETLLGTIMPEEESAKVC 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2720 AT---------EELSDLKKKYDASLKELAQLKGRQDLGRESDVLSQAAFPLTTsenISSRLEKLNQQLTSKDEQLLHLSS 2790
Cdd:TIGR00606  788 LTdvtimerfqMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDT---VVSKIELNRKLIQDQQEQIQHLKS 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2791 ------------------------ELESSHNQVQSFTKAMTSLQNERDHLWNELEKFRKSEEGKQRSAAPSAASSPAEVQ 2846
Cdd:TIGR00606  865 ktnelkseklqigtnlqrrqqfeeQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVN 944

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2847 SLKKAMSSLQNDRDRLLKELKNLQQQYLQmnQEITELRPLKAQLQESQDQTKALQmmkEELRQENLSWQHELHQLRVEKN 2926
Cdd:TIGR00606  945 DIKEKVKNIHGYMKDIENKIQDGKDDYLK--QKETELNTVNAQLEECEKHQEKIN---EDMRLMRQDIDTQKIQERWLQD 1019

                          890
                   ....*....|
gi 564376925  2927 SWELHERRMK 2936
Cdd:TIGR00606 1020 NLTLRKRENE 1029
PTZ00121 PTZ00121
MAEBL; Provisional
 48-435 2.44e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 2.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   48 DVLDRLADAEKLVLELKDIISKQDAQLQQKDEALQEEKKGAESKIKKIKLHA-KAKITSLNKQIEELKTQGGAASPPEV- 125
Cdd:PTZ00121 1305 DEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAdEAEAAEEKAEAAEKKKEEAKKKADAAk 1384

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  126 -QAEELSKHD---KSSTEEEMEVEKIKHELQEKEKLIsnlQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEK----- 196
Cdd:PTZ00121 1385 kKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKAD---EAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAkkaee 1461

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  197 -----EELIGALQTQLSQTQAEQAAQLSSMQQVVREK--DARFETQVRLHEDEL--LQLVTQSDVETEVQQKLRVMQ-RK 266
Cdd:PTZ00121 1462 akkkaEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKadEAKKAAEAKKKADEAkkAEEAKKADEAKKAEEAKKADEaKK 1541

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  267 LEEHEEA-------LLGRAQVVDLLQKELTSAEQRNQDLSQQLQLLEAEHSTLRNTMEAERQESKILMEKVELEMAER-- 337
Cdd:PTZ00121 1542 AEEKKKAdelkkaeELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKik 1621

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  338 KEELYQLQGQLERAGQAQAELEMQYGTLQQRHETEMEEKTACISLLQKNEQELQSACDALKEENSKLLQEQQ----EQAA 413
Cdd:PTZ00121 1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEAlkkeAEEA 1701

                         410       420
                  ....*....|....*....|..
gi 564376925  414 KSAQALQQLEDELQQKSKEISQ 435
Cdd:PTZ00121 1702 KKAEELKKKEAEEKKKAEELKK 1723
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1147-1928 2.59e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.89  E-value: 2.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1147 KPELEGKIVDLEKEKTQLQKKLQEALISRKAILKKAQEKEKHLKEELKEQKDAYRHLQEQfdgqskeneniaarLRQLQA 1226
Cdd:TIGR00618  189 KKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQK--------------REAQEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1227 KESTDQQLPGTGQQEPTHGSEGLSLEGTEPASESDLHAAQpshpgetatlqatvsVAQIQDQLKEIEVEKEELELKISST 1306
Cdd:TIGR00618  255 QLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAP---------------LAAHIKAVTQIEQQAQRIHTELQSK 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1307 TSELTKKSEEVLLLQEQ---INEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIADLEHLKTLQPELETLqkhvgqke 1383
Cdd:TIGR00618  320 MRSRAKLLMKRAAHVKQqssIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTL-------- 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1384 EEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHEERLKQVQVEIcelkkqpKELEEESKAKQQLQRKL 1463
Cdd:TIGR00618  392 TQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAI-------TCTAQCEKLEKIHLQES 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1464 QAALISRKEALKENKSLQEQLssardavehltksladvesqvsvqnQEKDALLGKLALLQEERDKLIVEMDKSLLENQSL 1543
Cdd:TIGR00618  465 AQSLKEREQQLQTKEQIHLQE-------------------------TRKKAVVLARLLELQEEPCPLCGSCIHPNPARQD 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1544 GGSCESLKLALGGLTEDKEKLMKELESVRCSKIAEST---EWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQE 1620
Cdd:TIGR00618  520 IDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKqraSLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDL 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1621 KQEVYAKLRSAESDKREREKQLQDAeQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQpvgganesMEALLSSNAS 1700
Cdd:TIGR00618  600 TEKLSEAEDMLACEQHALLRKLQPE-QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERV--------REHALSIRVL 670

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1701 LKEELERITLEYKTLSKEFEALMAEKNTLseETRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAVVGKSQEQDSL 1780
Cdd:TIGR00618  671 PKELLASRQLALQKMQSEKEQLTYWKEML--AQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKEL 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1781 SENAKLEDAEATLlansakpgvsetfsSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAK-DS 1859
Cdd:TIGR00618  749 MHQARTVLKARTE--------------AHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEiPS 814

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564376925  1860 ELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEERLmNQLAELNGSIGNYYQDVTDAQIKN 1928
Cdd:TIGR00618  815 DEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECS-KQLAQLTQEQAKIIQLSDKLNGIN 882
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 243-435 2.70e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 2.70e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  243 LLQLVTQSDVETEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQLQLLEAEhstlRNTMEAERQE 322
Cdd:COG4942    12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE----LAALEAELAE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  323 SKILMEKVELEMAERKEELYQLQGQLERAGQ-------------AQAELEMQY-GTLQQRHETEMEEKTACISLLQKNEQ 388
Cdd:COG4942    88 LEKEIAELRAELEAQKEELAELLRALYRLGRqpplalllspedfLDAVRRLQYlKYLAPARREQAEELRADLAELAALRA 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 564376925  389 ELQSAcdalKEENSKLLQEQQEQAAKSAQALQQLEDELQQKSKEISQ 435
Cdd:COG4942   168 ELEAE----RAELEALLAELEEERAALEALKAERQKLLARLEKELAE 210
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2672-2904 2.73e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.55  E-value: 2.73e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2672 EERVAELARDLVEMEQKLLTVTKENK--DLTAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASlkelaqlkgRQDLGR 2749
Cdd:COG3206   181 EEQLPELRKELEEAEAALEEFRQKNGlvDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAAL---------RAQLGS 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2750 ESDVLSQAAfplttsenISSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSftkamtsLQNERDhlwnELEKFRKSEEG 2829
Cdd:COG3206   252 GPDALPELL--------QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIA-------LRAQIA----ALRAQLQQEAQ 312

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564376925 2830 KQRSAAPSaasspaEVQSLKKAMSSLQNDRDRLLKELKNL---QQQYLQMNQEITELRPLKAQLQESQDQTKALQMMK 2904
Cdd:COG3206   313 RILASLEA------ELEALQAREASLQAQLAQLEARLAELpelEAELRRLEREVEVARELYESLLQRLEEARLAEALT 384
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 53-407 3.12e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.59  E-value: 3.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925    53 LADAEKLVLELKDIISKQDAQLQQKDEALQEEKKGAESKIKKIKLHAK------AKITSLNKQIEELKTQGGAASPPEVQ 126
Cdd:TIGR02168  700 LAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEEriaqlsKELTELEAEIEELEERLEEAEEELAE 779

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   127 AEELSKHDKSSTEE-EMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEKEELIGALQT 205
Cdd:TIGR02168  780 AEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   206 QLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQSDVETEVQQKLRVMQR---KLEEHEEALLGRAQVVD 282
Cdd:TIGR02168  860 EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEElreKLAQLELRLEGLEVRID 939

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   283 LLQKELTSAEQRNQdlsqqlqlleaehstlrntmeaerQESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQY 362
Cdd:TIGR02168  940 NLQERLSEEYSLTL------------------------EEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEY 995

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 564376925   363 GTLQQRHetemEEKTACISLLQKNEQELQSACDALKEENSKLLQE 407
Cdd:TIGR02168  996 EELKERY----DFLTAQKEDLTEAKETLEEAIEEIDREARERFKD 1036
PTZ00121 PTZ00121
MAEBL; Provisional
 52-435 3.32e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 3.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   52 RLADAEKLVLELKDIISKQDAQLQQKDEALQ---EEKKGAESKIKKIKlHAKAKITSLNKQIEELKTQGGAASPPEVQ-- 126
Cdd:PTZ00121 1278 RKADELKKAEEKKKADEAKKAEEKKKADEAKkkaEEAKKADEAKKKAE-EAKKKADAAKKKAEEAKKAAEAAKAEAEAaa 1356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  127 -----AEELSKHDKSSTEEE-MEVEKIKHELQEKEKliSNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKLQEKEELI 200
Cdd:PTZ00121 1357 deaeaAEEKAEAAEKKKEEAkKKADAAKKKAEEKKK--ADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  201 GALQTQLSQTQAEQAAQLSSMQQVVREKDARFETQVRlhEDELLQLVTQSDVETEVQQKLRVMQRKLEEHEEALLGRAQV 280
Cdd:PTZ00121 1435 EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK--ADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKA 1512

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  281 vdllqKELTSAEQRNQDLSQQLQLLEAEHSTLRNTMEAERQESkiLMEKVELEMAERKEELYQLQGQLERAGQAQAELEM 360
Cdd:PTZ00121 1513 -----DEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE--LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEE 1585

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  361 QYGTLQQRHETEM----EEKTACISLLQKNEQELQSACDALKEENSK----LLQEQQEQAAKSAQALQQLEDELQQKSKE 432
Cdd:PTZ00121 1586 AKKAEEARIEEVMklyeEEKKMKAEEAKKAEEAKIKAEELKKAEEEKkkveQLKKKEAEEKKKAEELKKAEEENKIKAAE 1665


                  ...
gi 564376925  433 ISQ 435
Cdd:PTZ00121 1666 EAK 1668
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 80-324 3.44e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   80 ALQEEKKGAESKIKKIKlhakAKITSLNKQIEELKTQGGAAsppevqAEELSKHDKSSTEEEMEVEKIKHELQEKEKLIS 159
Cdd:COG4942    17 AQADAAAEAEAELEQLQ----QEIAELEKELAALKKEEKAL------LKQLAALERRIAALARRIRALEQELAALEAELA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  160 NLQAQLDQAQSEQASQLDKSSAEMedFVLMRQKLQEKEELIgalqtqLSQTQAEQAAQLSSMQQVVREKDARFETQVRLH 239
Cdd:COG4942    87 ELEKEIAELRAELEAQKEELAELL--RALYRLGRQPPLALL------LSPEDFLDAVRRLQYLKYLAPARREQAEELRAD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  240 EDELLQLVTQSDVETEVQQKLRV-MQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQLQLLEAEHSTLRNTMEA 318
Cdd:COG4942   159 LAELAALRAELEAERAELEALLAeLEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                  ....*.
gi 564376925  319 ERQESK 324
Cdd:COG4942   239 AAERTP 244
PLN02939 PLN02939
transferase, transferring glycosyl groups
 760-1014 3.56e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.43  E-value: 3.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  760 ELETSLAEAEKQRGLDYESQRAQHNLLTEQIhslsiEAKSKDVKIETLQRELDGVQL---QFSEQGTQIRSLQSQLQTKE 836
Cdd:PLN02939   74 QLENTSLRTVMELPQKSTSSDDDHNRASMQR-----DEAIAAIDNEQQTNSKDGEQLsdfQLEDLVGMIQNAEKNILLLN 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  837 SEVLEGAERMKDISKEMEELSQALSQKELEIAQMD---QLLLEKKKDVETLQQTIQEKDQQVTELS-------FSMTEKM 906
Cdd:PLN02939  149 QARLQALEDLEKILTEKEALQGKINILEMRLSETDariKLAAQEKIHVEILEEQLEKLRNELLIRGateglcvHSLSKEL 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  907 VQLNEEKFSLGVEIKTLKEQLSLLSRA-EGAKKEQVEDSGAESSPKHGPHE-SSAQEPVCK-DALQQELEWLRKESEQ-- 981
Cdd:PLN02939  229 DVLKEENMLLKDDIQFLKAELIEVAETeERVFKLEKERSLLDASLRELESKfIVAQEDVSKlSPLQYDCWWEKVENLQdl 308

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 564376925  982 ----RKRKLQAALI--SRKELLQKVSKLEEEL--AKVREES 1014
Cdd:PLN02939  309 ldraTNQVEKAALVldQNQDLRDKVDKLEASLkeANVSKFS 349
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 792-1092 3.82e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.60  E-value: 3.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   792 SLSIEAKSKDVKIETLQRELDGVQLQFSeqgtqirSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMD 871
Cdd:TIGR02169  664 GGILFSRSEPAELQRLRERLEGLKRELS-------SLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLK 736

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   872 QLLLEKKKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLG--------VEIKTLKEQLSLLSRAEGAKKEQVED 943
Cdd:TIGR02169  737 ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNdlearlshSRIPEIQAELSKLEEEVSRIEARLRE 816

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   944 SGAESSPKHGPHESSAQEPVCKDALQQELEWLRKESEQRKRKLQAALISRKELLQKVSKLEEELAKVREESTKDSLR-ES 1022
Cdd:TIGR02169  817 IEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDElEA 896

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564376925  1023 EKRELEEdsKNKDDPEKYGTSEWRELEVSLRLTISEKEV-ELEGIRRDLKEKAAAE---EELQALVQRMTQDLQ 1092
Cdd:TIGR02169  897 QLRELER--KIEELEAQIEKKRKRLSELKAKLEALEEELsEIEDPKGEDEEIPEEElslEDVQAELQRVEEEIR 968
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1807-2330 4.34e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.05  E-value: 4.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1807 SSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNAL---LTQISAKDSELKLLEEEVAKInmlNQQIQEELS 1883
Cdd:PRK01156  194 SSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLksaLNELSSLEDMKNRYESEIKTA---ESDLSMELE 270

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1884 RVTKLKETAEEEKDDLEERLMNQLAELNGSIgNYYQDVTDAQIKNEQLESEMQNLK---RCVSELEEEKQQLVKEKTKVE 1960
Cdd:PRK01156  271 KNNYYKELEERHMKIINDPVYKNRNYINDYF-KYKNDIENKKQILSNIDAEINKYHaiiKKLSVLQKDYNDYIKKKSRYD 349

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1961 sEIRKEYMEKIQGAQKGPGSKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDATKGNL 2040
Cdd:PRK01156  350 -DLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSL 428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2041 AQAVEHHKKAQAELSSFKILL-----------DDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDE---DLLRRLEQ 2106
Cdd:PRK01156  429 NQRIRALRENLDELSRNMEMLngqsvcpvcgtTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEkivDLKKRKEY 508

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2107 AEEKHRKEKKNMQEKLDALHREKAHVEDTLAEIqvsltrKDKDMKelqqsldstLAQLAAFTKSMsSLQDDRDRVIDEAK 2186
Cdd:PRK01156  509 LESEEINKSINEYNKIESARADLEDIKIKINEL------KDKHDK---------YEEIKNRYKSL-KLEDLDSKRTSWLN 572

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2187 KWEQRFGDAIQTKEEEVRLKEENCTALKDQLRQMTIHMEELKI----TVSRLEHD--------KEIWESKAQTE-LQHQQ 2253
Cdd:PRK01156  573 ALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSyidkSIREIENEannlnnkyNEIQENKILIEkLRGKI 652

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925 2254 KAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLESELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNCK 2330
Cdd:PRK01156  653 DNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMK 729
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 802-1088 4.39e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.07  E-value: 4.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  802 VKIETLQRELDGV--QLQfSEQGTQIRSLQsqlQTKESEVLEGA-ERMKDISKEMEELSQALSQKELEIAQMDQLlleKK 878
Cdd:PRK05771    9 VLIVTLKSYKDEVleALH-ELGVVHIEDLK---EELSNERLRKLrSLLTKLSEALDKLRSYLPKLNPLREEKKKV---SV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  879 KDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSL-------------GVEIKTLKEQLSLLSRAEGAKKEQVEDSG 945
Cdd:PRK05771   82 KSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELeqeierlepwgnfDLDLSLLLGFKYVSVFVGTVPEDKLEELK 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  946 AESSPKHgpHESSAQEP-------VCKDALQQELEWLRKESEQRKRKLQaaliSRKELLQKVSKLEEELAKVREEstKDS 1018
Cdd:PRK05771  162 LESDVEN--VEYISTDKgyvyvvvVVLKELSDEVEEELKKLGFERLELE----EEGTPSELIREIKEELEEIEKE--RES 233

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925 1019 LRESEKRELEEDSKNKDDPEKYGTSEWRELEVSLRLTISEKEVELEG--IRRDLKekaaaeeELQALVQRMT 1088
Cdd:PRK05771  234 LLEELKELAKKYLEELLALYEYLEIELERAEALSKFLKTDKTFAIEGwvPEDRVK-------KLKELIDKAT 298
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 713-1430 4.67e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.12  E-value: 4.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   713 LTQLTKEFKESAEEARSTLTAVCEERDQLLYRVKELDVLGELRAQVRELETSLAEAEKQRGlDYESQRAQHNLLTEQIHS 792
Cdd:TIGR00618  224 LEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQE-RINRARKAAPLAAHIKAV 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   793 LSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKELEIAQMDQ 872
Cdd:TIGR00618  303 TQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIH 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   873 LLLEKKKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQvedsgaesspkh 952
Cdd:TIGR00618  383 TLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCT------------ 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   953 gphessAQEPVCKDALQQELEWLRKESEQRKRKLQAALISRKELLQKVSKLEEELAKVREESTKDSLRESEKRELEEDSK 1032
Cdd:TIGR00618  451 ------AQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1033 NKDDPEKYGTSEWRELEVSLRLTISEKEVELEGIRRDLKEKAAAEEELQALVQ---RMTQDLQNKTKQIDLLQEEITENQ 1109
Cdd:TIGR00618  525 PLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQcdnRSKEDIPNLQNITVRLQDLTEKLS 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1110 ATIQKfitgtmdagdgdsavketsvssppRAGGGEHWKPELEGKIVDLEKEKTQLQKKLQEALisrkAILKKAQEKEKHL 1189
Cdd:TIGR00618  605 EAEDM------------------------LACEQHALLRKLQPEQDLQDVRLHLQQCSQELAL----KLTALHALQLTLT 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1190 KEELKEQKDAYRHLQEQFDGQskeneniaaRLRQLQAKESTDQQLPGTGQQEPTHGSEGLSLEGTEPASESDLHAAQPSH 1269
Cdd:TIGR00618  657 QERVREHALSIRVLPKELLAS---------RQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENAS 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1270 PGETATLQATVSVAQiqdqlKEIEVEKEELELKISSTTSELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLK 1349
Cdd:TIGR00618  728 SSLGSDLAAREDALN-----QSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1350 QELESSQLKIADLEHLKTLQPEletlqkhvgQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHE 1429
Cdd:TIGR00618  803 TLEAEIGQEIPSDEDILNLQCE---------TLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQ 873


                   .
gi 564376925  1430 E 1430
Cdd:TIGR00618  874 L 874
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1880-2542 4.71e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 4.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1880 EELSRVTKLKETAEEEKDDLE---------ERLMNQLAELN--GSIGNYYQdvtdAQIKNEQLESEMQNLKRCVSELEEE 1948
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEpirelaeryAAARERLAELEylRAALRLWF----AQRRLELLEAELEELRAELARLEAE 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1949 KQQLVKEKTKVESEIRkEYMEKIQGAQkgpGSKIhaKELQELLKEKQQEVKQLQKdcirylgRISALEKTVKALEFVHTE 2028
Cdd:COG4913   311 LERLEARLDALREELD-ELEAQIRGNG---GDRL--EQLEREIERLERELEERER-------RRARLEALLAALGLPLPA 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2029 SQKDLDATKGNLAQAVEhhkkaqaELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESI---KSQIKQKDEDLLRRLE 2105
Cdd:COG4913   378 SAEEFAALRAEAAALLE-------ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLerrKSNIPARLLALRDALA 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2106 QA-----------------------------------------EEKHRK------EKKNMQEKLDALHREKAHVEDTLAE 2138
Cdd:COG4913   451 EAlgldeaelpfvgelievrpeeerwrgaiervlggfaltllvPPEHYAaalrwvNRLHLRGRLVYERVRTGLPDPERPR 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2139 IQV-SLTRK-DKDMKELQQSLDSTLAQLAAFTK--SMSSLQDDRDRVIDE--AKKWEQRFgdaiqTKEEEVRLKEENCT- 2211
Cdd:COG4913   531 LDPdSLAGKlDFKPHPFRAWLEAELGRRFDYVCvdSPEELRRHPRAITRAgqVKGNGTRH-----EKDDRRRIRSRYVLg 605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2212 --------ALKDQLRQMTIHMEELKITVSRLEHDKEIWESKAQTELQHQQkaydkLQEENKELMSQLEEAGQLyhdsKNE 2283
Cdd:COG4913   606 fdnraklaALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE-----YSWDEIDVASAEREIAEL----EAE 676

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2284 LTKLE---SELKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNCKFNCEQLETDLTAsRELTTRLHDEINVKEQK 2360
Cdd:COG4913   677 LERLDassDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA-AEDLARLELRALLEERF 755

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2361 IISLLSGKEEAIQVAIAELHQQHSKEIKELEnllsqeeeenltleeenkravektNQLTEALETIKKESLEQKAQLDSFV 2440
Cdd:COG4913   756 AAALGDAVERELRENLEERIDALRARLNRAE------------------------EELERAMRAFNREWPAETADLDADL 811

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2441 KSMSSLQDDRDRIVSD-----YRQLEErhlsviLEKDELIQDAAAENNKLKEEIRGLRGHMDDLNSE------------- 2502
Cdd:COG4913   812 ESLPEYLALLDRLEEDglpeyEERFKE------LLNENSIEFVADLLSKLRRAIREIKERIDPLNDSlkripfgpgrylr 885

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|...
gi 564376925 2503 ---NAKLDAELIQYRRDLNEVITIKDSQQRQLLEAQLQQNKEL 2542
Cdd:COG4913   886 leaRPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRL 928
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1830-2043 5.14e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 5.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1830 EMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAE 1909
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1910 L--NGSIGNYY------QDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKgpgsk 1981
Cdd:COG3883    95 LyrSGGSVSYLdvllgsESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAA----- 169

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925 1982 ihAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQA 2043
Cdd:COG3883   170 --KAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2644-2867 5.63e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 5.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2644 SEIEDKLKRELKHLHHNAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLTAQIQAFGKSMSSLQDSRDHATEE 2723
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2724 LSDLKKKYDASLKElAQLKGRQDlgRESDVLSQAAFplTTSENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSFT 2803
Cdd:COG4942    99 LEAQKEELAELLRA-LYRLGRQP--PLALLLSPEDF--LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564376925 2804 KAMTSLQNERDHLWNELEKFRKSEEGKQRSAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELK 2867
Cdd:COG4942   174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
mukB PRK04863
chromosome partition protein MukB;
2565-2976 5.66e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.10  E-value: 5.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2565 MSLDALQEeNQGLSKEIKSFKEQLTAlHEEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKV- 2643
Cdd:PRK04863  244 MTLEAIRV-TQSDRDLFKHLITESTN-YVAADYMRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNe 321

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2644 --SEIEDKLKRELKHLH--HNAGIMRNETETAEERVAELARDLVEMEQklltVTKENKDLTAQIQAfgkSMSSLQDSRDH 2719
Cdd:PRK04863  322 aeSDLEQDYQAASDHLNlvQTALRQQEKIERYQADLEELEERLEEQNE----VVEEADEQQEENEA---RAEAAEEEVDE 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2720 ATEELSDLKKKYDASLKELAQLKGRQDLGRESDVLSQAafPLTTSENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQV 2799
Cdd:PRK04863  395 LKSQLADYQQALDVQQTRAIQYQQAVQALERAKQLCGL--PDLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAH 472

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2800 QSFTKAMTSLQN-----ERDHLWNE-LEKFRKSEEgkQRSAAPSAASSPAEVQSLKKAMsSLQNDRDRLLKElknLQQQY 2873
Cdd:PRK04863  473 SQFEQAYQLVRKiagevSRSEAWDVaRELLRRLRE--QRHLAEQLQQLRMRLSELEQRL-RQQQRAERLLAE---FCKRL 546

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2874 LQMNQEITELRPLKAQLQESQDQtkaLQMMKEELRQENLSWQHELHQLRVEKNS-------W-ELHER--RMKEQYLMAI 2943
Cdd:PRK04863  547 GKNLDDEDELEQLQEELEARLES---LSESVSEARERRMALRQQLEQLQARIQRlaarapaWlAAQDAlaRLREQSGEEF 623

                         410       420       430
                  ....*....|....*....|....*....|...
gi 564376925 2944 SDKDQQLGHLQNLLRELRSSSQTQILPTQYQRQ 2976
Cdd:PRK04863  624 EDSQDVTEYMQQLLERERELTVERDELAARKQA 656
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 73-359 6.17e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.50  E-value: 6.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925    73 QLQQKDEALQEEKKGAESKikkiklhAKAKITSLNKQIEELKTQGGAASppEVQAEELSKHDKSSTEEEMEVEKIKHELQ 152
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKE-------EKAREVERRRKLEEAEKARQAEM--DRQAAIYAEQERMAMERERELERIRQEER 358

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   153 EKEKLISNLQA---------QLDQAQSEQASQLDKSSAEMEdfVLMRQKLQEKEE--LIGALQTQLSQTQAEQAAQLSSM 221
Cdd:pfam17380  359 KRELERIRQEEiameisrmrELERLQMERQQKNERVRQELE--AARKVKILEEERqrKIQQQKVEMEQIRAEQEEARQRE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   222 QQVVREKDARFETQVRLHEDEllqlvTQSDVETEVQQKLRVMQRKLE---EHEEALLGRAQVVDLLQKELTSAEQRNQDL 298
Cdd:pfam17380  437 VRRLEEERAREMERVRLEEQE-----RQQQVERLRQQEEERKRKKLElekEKRDRKRAEEQRRKILEKELEERKQAMIEE 511

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925   299 SQQLQLLEAEHSTLRNTMEAERQESKILME-KVELEMAERKeelyQLQGQLERAGQAQAELE 359
Cdd:pfam17380  512 ERKRKLLEKEMEERQKAIYEEERRREAEEErRKQQEMEERR----RIQEQMRKATEERSRLE 569
PRK11281 PRK11281
mechanosensitive channel MscK;
1360-1546 6.48e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 45.67  E-value: 6.48e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1360 ADLEHLKTLQPELETLQKHvGQKEEEVSYLVGQLgekEQTLTTVQTeMEEQERLIKALHTQLEmQAkehEERLKQVQVEI 1439
Cdd:PRK11281   33 GDLPTEADVQAQLDALNKQ-KLLEAEDKLVQQDL---EQTLALLDK-IDRQKEETEQLKQQLA-QA---PAKLRQAQAEL 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1440 CELKKQPKELEEESKAKQ---QLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSLAdvESQVSVQ---NQEKD 1513
Cdd:PRK11281  104 EALKDDNDEETRETLSTLslrQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALY--ANSQRLQqirNLLKG 181

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 564376925 1514 ALLGKLALLQEERDKLIVEMD----KSLLENQSLGGS 1546
Cdd:PRK11281  182 GKVGGKALRPSQRVLLQAEQAllnaQNDLQRKSLEGN 218
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1309-1445 7.05e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 44.15  E-value: 7.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1309 ELTKKSEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLK---IADLEHLKTLQPELETLQKHVGQKEEE 1385
Cdd:COG1579    32 ELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQlgnVRNNKEYEALQKEIESLKRRISDLEDE 111

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1386 VSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHEERLKQVQVEICELKKQ 1445
Cdd:COG1579   112 ILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 190-418 7.05e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 7.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  190 RQKLQEKEELIGALQTQLSQTQAEQAAQLSSMQQVVREKDARfETQVRLHEDELLQLVTQsdvETEVQQKLRVMQRKLEE 269
Cdd:COG4942    26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL-ARRIRALEQELAALEAE---LAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  270 HEEALlgrAQVVDLLQKeltsAEQRNQDLSQQLQLLEAEHSTLRNTMEAERQESKILMEkvelEMAERKEELYQLQGQLE 349
Cdd:COG4942   102 QKEEL---AELLRALYR----LGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE----ELRADLAELAALRAELE 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564376925  350 RAGQAQAELEMQYGTLQQRHETEMEEKTACISLLQKNEQELQSACDALKEENSKLLQEQQEQAAKSAQA 418
Cdd:COG4942   171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1825-2420 8.19e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.10  E-value: 8.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1825 RIAELEMEKQKDRELSQTLENEKNALLT-----QISAKDSELKL---LEEEVAKINMLNQQIQEELSrvtklketaeeEK 1896
Cdd:pfam05483  170 KTKKYEYEREETRQVYMDLNNNIEKMILafeelRVQAENARLEMhfkLKEDHEKIQHLEEEYKKEIN-----------DK 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1897 DDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVeseirKEYMEKIQGAQK 1976
Cdd:pfam05483  239 EKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDI-----KMSLQRSMSTQK 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1977 G--PGSKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAVEHHKKAQAEL 2054
Cdd:pfam05483  314 AleEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2055 SSFKILLDDTQ---SEAARVLADNLKLKKElQSNKESIKSQIKQKDEDLLRRLEQAEekhrKEKKNMQEKLDALHREKAH 2131
Cdd:pfam05483  394 EEMTKFKNNKEvelEELKKILAEDEKLLDE-KKQFEKIAEELKGKEQELIFLLQARE----KEIHDLEIQLTAIKTSEEH 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2132 VEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQ---DDRDRVIDEAKKWEQRFGDAIQTKEE-EVRLKE 2207
Cdd:pfam05483  469 YLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTlelKKHQEDIINCKKQEERMLKQIENLEEkEMNLRD 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2208 E----------NCTALKDQLRQMTIHMEELKITVSRLEHDKEIWESKA---QTELQHQQKAYDKLQEENKELMSQLEEAG 2274
Cdd:pfam05483  549 ElesvreefiqKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCnnlKKQIENKNKNIEELHQENKALKKKGSAEN 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2275 QLYHDSKNELTKLESELKSLKDQSTDLKNSLEKCRE----HENNLEGIIKQQEADI-------QNCKFNCEQLETDLTAS 2343
Cdd:pfam05483  629 KQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEdkkiSEEKLLEEVEKAKAIAdeavklqKEIDKRCQHKIAEMVAL 708

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925  2344 RELTTRLHDEINVKEQKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLSQEEEENLTLEEENKRAVEKTNQLTE 2420
Cdd:pfam05483  709 MEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2526-2744 9.63e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 9.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2526 SQQRQLLEAQLQQNKELRNECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHEEGALAVYHAQLR 2605
Cdd:COG4942    37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRL 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2606 VREEEVQKLTAALSSSQK-RTVDLQEELVCVQKEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAEERVAELARDLVE 2684
Cdd:COG4942   117 GRQPPLALLLSPEDFLDAvRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAE 196

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2685 MEQKLLTVTKENKDLTAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASlkELAQLKGR 2744
Cdd:COG4942   197 RQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA--GFAALKGK 254
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2765-3052 1.08e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.93  E-value: 1.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2765 ENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSFTKAMTSLQNERDHLWNELEKFRKSEEGKQRsaapsaasspaE 2844
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-----------D 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2845 VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMNQEITELRPLKAQLQESQDQTKALQMMKEELRQENLSWQHELHQLRVE 2924
Cdd:COG1196   304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2925 KNSWELHERRMKEQYLMAISDKDQQLGHLQNLLRELRSSSQTQILPTQYQRQASSGTSAALDGSQNLVYETDCLRTQLND 3004
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 564376925 3005 SLKEIHQKELRIQQLNSKFSQLLEEKNilstQLRDANQSLRDSQHHYS 3052
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAA----ARLLLLLEAEADYEGFL 507
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 736-951 1.09e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  736 EERDQLLYRVKEL-DVLGELRAQVRELETSLAEAEKQrgldYESQRAQHNLLTEQIHSLSIEAKSKDVKIETLQRELDGV 814
Cdd:COG4942    27 AELEQLQQEIAELeKELAALKKEEKALLKQLAALERR----IAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  815 QLQFSEqgtQIRSLQSQLQTKESEVLEGAE----------RMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETL 884
Cdd:COG4942   103 KEELAE---LLRALYRLGRQPPLALLLSPEdfldavrrlqYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564376925  885 QQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQ----LSLLSRAEGAKKEQVEDSGAESSPK 951
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEaeelEALIARLEAEAAAAAERTPAAGFAA 250
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1830-2910 1.17e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 44.78  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1830 EMEKQKDRELSQTLENEKNAlltqisakDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEER---LMNQ 1906
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKA--------ESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARkqeLEEI 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1907 LAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRK---------EYMEKIQGAQKG 1977
Cdd:pfam01576   77 LHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKleedillleDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1978 PGSKIhaKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAVEHHKKAQAELSSF 2057
Cdd:pfam01576  157 LEERI--SEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAEL 234

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2058 KILLDDTQSEAARVLA---DNLKLKKELQSNKESIKSQIKQKDEDLLRRlEQAEEKHRKEKKNMQEKLDALHREKAHVED 2134
Cdd:pfam01576  235 RAQLAKKEEELQAALArleEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQRRDLGEELEALKTELEDTLD 313

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2135 TLAEIQVSLTRKDKDMKELQQSLDSTL----AQLAAFTKSMSSLQDDRDRVIDEAKKWEQRFGDAIQTKEEEVrlkeenc 2210
Cdd:pfam01576  314 TTAAQQELRSKREQEVTELKKALEEETrsheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESEN------- 386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2211 TALKDQLRQMTIHMEELKITVSRLEHDKEIWESKAQTELQHQQKAYDKLQEenkeLMSQLEEAGQLYHDSKNELTKLESE 2290
Cdd:pfam01576  387 AELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSK----LQSELESVSSLLNEAEGKNIKLSKD 462

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2291 LKSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNCKfncEQLETDLTASRELTTRLHdeinvKEQKIISLLSGKEE 2370
Cdd:pfam01576  463 VSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQ---EQLEEEEEAKRNVERQLS-----TLQAQLSDMKKKLE 534

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2371 AIQVAIAELHQQHSKEIKELENLLSQEEEENLTLEEENK---RAVEKTNQLTEALETIKK--ESLEQKA----QLDSFVK 2441
Cdd:pfam01576  535 EDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKtknRLQQELDDLLVDLDHQRQlvSNLEKKQkkfdQMLAEEK 614

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2442 SMSS-LQDDRDRIVSDYRQLEERHLSVILEKDELiQDAAAEnnkLKEEIRGLRGHMDDLNSENAKLDAELIQYRRdlnev 2520
Cdd:pfam01576  615 AISArYAEERDRAEAEAREKETRALSLARALEEA-LEAKEE---LERTNKQLRAEMEDLVSSKDDVGKNVHELER----- 685

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2521 itikdsqQRQLLEAQLQqnkELRNECVKLEGRLKGSEAEKQSLQMSLDALQEENQglsKEIKSFKEQLTALHEEGALAVY 2600
Cdd:pfam01576  686 -------SKRALEQQVE---EMKTQLEELEDELQATEDAKLRLEVNMQALKAQFE---RDLQARDEQGEEKRRQLVKQVR 752

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2601 HAQLRVREEEVQKlTAALSSSQKRTVDLQEelVCVQKEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAEERVAELAR 2680
Cdd:pfam01576  753 ELEAELEDERKQR-AQAVAAKKKLELDLKE--LEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSK 829

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2681 dlvEMEQKLLTVTKENKDLTAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGRQDLGRESDVLSQAafp 2760
Cdd:pfam01576  830 ---ESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQS--- 903

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2761 ltTSENISSRLEKLNQQLTSkdeqllhLSSELESSHNQVQSFTKAMTSLQNERDHLWNELEKFRKSEEGKQRSA------ 2834
Cdd:pfam01576  904 --NTELLNDRLRKSTLQVEQ-------LTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSSiaalea 974

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2835 APSAASSPAEVQSLKKAMSS-LQNDRDRLLKEL--------KNLQQQYLQMNQEITELRPLKAQLQESQDQTKALQMMKE 2905
Cdd:pfam01576  975 KIAQLEEQLEQESRERQAANkLVRRTEKKLKEVllqvederRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARR 1054


                   ....*
gi 564376925  2906 ELRQE 2910
Cdd:pfam01576 1055 KLQRE 1059
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 306-1122 1.20e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.96  E-value: 1.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   306 EAEHSTLRNTMEAERQESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQYGTLQQRHETEMEEKTACISLLQK 385
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   386 NEQELQSACDALKEENSKLLQEQQEQAAKSAQalQQLEDELQQKSKEISQFVNKPNLEKHETSSQTSLPDVYNEGVQAVM 465
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKE--KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   466 EESVASLQKRVLELENEKGALLLSSLELEELRAENEKLCSRITLLEAQNRAGEADGMVCEVSTAGIALLNRSDSSTEESG 545
Cdd:pfam02463  327 EKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   546 QDVLENTFSQKHKELSVL-------------LVEMKEAQEEIAFLKSQLQGKRPEGDYEVLDRKEVQMMESEGLPSVTAR 612
Cdd:pfam02463  407 AQLLLELARQLEDLLKEEkkeeleileeeeeSIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   613 DVLCA--------PRDKNSVPAVEGEQAGMRDQHGTLEAGPLNDTGMELNSPQPDGVDKSLSAP------HVCLCHQGEL 678
Cdd:pfam02463  487 ELLLSrqkleersQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIvevsatADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   679 ERLKTQVLELETSLHTAKETHEKNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLYRVKELDVLGELRAQV 758
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   759 RELETSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESE 838
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   839 VLEGAERMKDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVET------LQQTIQEKDQQVTELSFSMTEKMVQLNEE 912
Cdd:pfam02463  727 VQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLkekelaEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   913 KFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAESSPKHGPHESSAQEPVCKDALQQELEWLRKESEQRKRKLQAALIS 992
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   993 RKELLQKVSKLEEELAKVREEStKDSLRESEKRELEEDSKNKDDPEKYGTSEWRELEVSLRLTISEKEV-ELEGIRRDLK 1071
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQK-LNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNkEEEEERNKRL 965

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 564376925  1072 EKAAAEEELQALVQRMTQDLQNKTKQIDLLQEEITENQATIQKFITGTMDA 1122
Cdd:pfam02463  966 LLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETC 1016
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2448-2932 1.25e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.65  E-value: 1.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2448 DDRDRIVSDYRQLEERHLSVILEKDELIQDAAA---ENNKLKEEIRGLRGHMDDLNSENAKLDAEL------IQYRRDLN 2518
Cdd:PRK02224  237 DEADEVLEEHEERREELETLEAEIEDLRETIAEterEREELAEEVRDLRERLEELEEERDDLLAEAglddadAEAVEARR 316

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2519 EVITIKDSQQRQLLEAQLQQNKELRNECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHEE-GAL 2597
Cdd:PRK02224  317 EELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEiEEL 396

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2598 AVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKVSEIEDKLK--------RELKHLHHNAGImrnetE 2669
Cdd:PRK02224  397 RERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEagkcpecgQPVEGSPHVETI-----E 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2670 TAEERVAELARDLVEMEQKLLTVTKENKDLTAQIQAfGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGR-QDLG 2748
Cdd:PRK02224  472 EDRERVEELEAELEDLEEEVEEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRETIEEKRERAEELRERaAELE 550

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2749 RESDVLSQAAFPL-TTSENISSRLEKLNQQLTSKDEQLLHLSsELESSHNQVQSFTKAMTSLQNERDHlWNEL-----EK 2822
Cdd:PRK02224  551 AEAEEKREAAAEAeEEAEEAREEVAELNSKLAELKERIESLE-RIRTLLAAIADAEDEIERLREKREA-LAELnderrER 628

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2823 FRKSEEGKQRSAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELK----NLQQQYLQMNQEITELRPLKAQLQESQDQTK 2898
Cdd:PRK02224  629 LAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELReerdDLQAEIGAVENELEELEELRERREALENRVE 708

                         490       500       510
                  ....*....|....*....|....*....|....*..
gi 564376925 2899 ALQMMKEELRQENLSW---QHELHQLRVEKNSWELHE 2932
Cdd:PRK02224  709 ALEALYDEAEELESMYgdlRAELRQRNVETLERMLNE 745
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2528-2741 1.51e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2528 QRQLLEAQLQQNKELRNECVKLEGRLKGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHEE-GALAVYHAQLRV 2606
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAElAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2607 REEEVQKLTAALSSSQKRTVDLQEELVCVQKEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAEERVAELARDLVEME 2686
Cdd:COG4942    98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 564376925 2687 QKLLTVTKENKDLTAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQL 2741
Cdd:COG4942   178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARL 232
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 786-928 1.60e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 43.65  E-value: 1.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   786 LTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEELSQALSQKE- 864
Cdd:pfam15905  161 LMKLRNKLEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVSEQVEk 240

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564376925   865 --LEIAQMDQLLLEKKKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLS 928
Cdd:pfam15905  241 ykLDIAQLEELLKEKNDEIESLKQSLEEKEQELSKQIKDLNEKCKLLESEKEELLREYEEKEQTLN 306
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1392-1631 1.66e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1392 QLGEKEQTLTTVQTEMEEQERLIKALHTQ---LEMQAKEHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALI 1468
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEekaLLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1469 SRKEALKENKSLQeQLSSARDAVEHL--TKSLADVESQVSVQNQEKDALLGKLALLQEERDKLivemdksllenqslggs 1546
Cdd:COG4942   101 AQKEELAELLRAL-YRLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL----------------- 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1547 cESLKLALGGLTEDKEKLMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYA 1626
Cdd:COG4942   163 -AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241


                  ....*
gi 564376925 1627 KLRSA 1631
Cdd:COG4942   242 RTPAA 246
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
803-989 1.86e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  803 KIETLQRELDGVQLQFSEQGTQIRSLQSQLQT--KESEVLEGAERMKDISKEMEELSQALSQKELEIAQmdqlLLEKKKD 880
Cdd:COG4913   611 KLAALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDASSDD 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  881 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAESSPKHGPH-ESSA 959
Cdd:COG4913   687 LAALEEQLEELEAELEE-----------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALlEERF 755

                         170       180       190
                  ....*....|....*....|....*....|
gi 564376925  960 QEPVCKDALQQELEWLRKESEQRKRKLQAA 989
Cdd:COG4913   756 AAALGDAVERELRENLEERIDALRARLNRA 785
PLN02939 PLN02939
transferase, transferring glycosyl groups
 2250-2627 1.92e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.12  E-value: 1.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2250 QHQQKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLESelkSLKDQSTDLKNSLEKCREHENNLEGIIKQQEADIQNc 2329
Cdd:PLN02939   38 RRRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLEN---TSLRTVMELPQKSTSSDDDHNRASMQRDEAIAAIDN- 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2330 kfncEQLETDLTASRELTTRLHDEINV---KEQKIISLLSGKEEAIQVAIAELHQQHS--KEIKELENLLSQEEEENLTL 2404
Cdd:PLN02939  114 ----EQQTNSKDGEQLSDFQLEDLVGMiqnAEKNILLLNQARLQALEDLEKILTEKEAlqGKINILEMRLSETDARIKLA 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2405 EEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhLSVILEKDELIQDAAAENNK 2484
Cdd:PLN02939  190 AQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAE-LIEVAETEERVFKLEKERSL 268

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2485 LKEEIRGLRGHMDDLNSENAKLDAelIQYRRDLNEVITIKDSQQRQLLEAQ-----LQQNKELRNECVKLEGRLKGSEAE 2559
Cdd:PLN02939  269 LDASLRELESKFIVAQEDVSKLSP--LQYDCWWEKVENLQDLLDRATNQVEkaalvLDQNQDLRDKVDKLEASLKEANVS 346

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925 2560 KQSLQMsLDALQEenqglskEIKSFKEQLTALHEEgalavYHAQLRVREEEVQKLTAALSS----SQKRTVD 2627
Cdd:PLN02939  347 KFSSYK-VELLQQ-------KLKLLEERLQASDHE-----IHSYIQLYQESIKEFQDTLSKlkeeSKKRSLE 405
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2042-2746 1.93e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.06  E-value: 1.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2042 QAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKqkDEDLLRRLEqaEEKHRKEK-KNMQE 2120
Cdd:pfam12128  176 SPLRHIDKIAKAMHSKEGKFRDVKSMIVAILEDDGVVPPKSRLNRQQVEHWIR--DIQAIAGIM--KIRPEFTKlQQEFN 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2121 KLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAqlaaftksmsSLQDDRDRVIDEAKKWEQRFGDAIQTKE 2200
Cdd:pfam12128  252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLR----------TLDDQWKEKRDELNGELSAADAAVAKDR 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2201 EEVRLKEENCTA-LKDQLRQMTIHMEELKITVSRLEHDKEiwESKAQTELQHQ-QKAYDKLQEE------------NKEL 2266
Cdd:pfam12128  322 SELEALEDQHGAfLDADIETAAADQEQLPSWQSELENLEE--RLKALTGKHQDvTAKYNRRRSKikeqnnrdiagiKDKL 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2267 MSQLEEAGQLYHDSKNELTKLESELKS-LKDQSTDLKNSLEKCREHENNLEGIIKQQEA------DIQNCKFNCEQLETD 2339
Cdd:pfam12128  400 AKIREARDRQLAVAEDDLQALESELREqLEAGKLEFNEEEYRLKSRLGELKLRLNQATAtpelllQLENFDERIERAREE 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2340 LTASRELTTRLHDEINV------KEQKIISLLSGKEEAIQVAIAELHQQHSKEIKELENLLSQEEEENLtleeenkrave 2413
Cdd:pfam12128  480 QEAANAEVERLQSELRQarkrrdQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWE----------- 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2414 ktnqltEALETIKKESLEQKAQLDSFVKSMSSLQD--------DRDRI-VSDYRQLEERHLSVILEKDELIQDAAAENNK 2484
Cdd:pfam12128  549 ------QSIGKVISPELLHRTDLDPEVWDGSVGGElnlygvklDLKRIdVPEWAASEEELRERLDKAEEALQSAREKQAA 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2485 LKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVITIKDSQQRQLLEAqlqqnkelrnecvklegrlkgSEAEKQSLQ 2564
Cdd:pfam12128  623 AEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKA---------------------LAERKDSAN 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2565 MSLDALQEENQGLSKEIKSFKEQLTALHEEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCVQKE-----A 2639
Cdd:pfam12128  682 ERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWykrdlA 761

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2640 SKKVSEIED-KLKRELKHLHHN-AGIMRNETETAEERV----------AELARDLVEMEQKLLTVTKENKDLTAQIQAFG 2707
Cdd:pfam12128  762 SLGVDPDVIaKLKREIRTLERKiERIAVRRQEVLRYFDwyqetwlqrrPRLATQLSNIERAISELQQQLARLIADTKLRR 841

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 564376925  2708 KSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGRQD 2746
Cdd:pfam12128  842 AKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDAN 880
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 675-1033 2.37e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 43.69  E-value: 2.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  675 QGELERLKTQVLELETSLHTAKETHEKNLSEKAKEissltQLTKEFKESAEEA--RSTLTAVCEE------RDQLLYRV- 745
Cdd:PLN03229  435 EGEVEKLKEQILKAKESSSKPSELALNEMIEKLKK-----EIDLEYTEAVIAMglQERLENLREEfskansQDQLMHPVl 509

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  746 -KELDVLGElraqvrELETSLAEAEkqrglDYESQRAQHNLLTEqiHSLSIEAKSKDVKIETLQRELDG---VQLQFSEQ 821
Cdd:PLN03229  510 mEKIEKLKD------EFNKRLSRAP-----NYLSLKYKLDMLNE--FSRAKALSEKKSKAEKLKAEINKkfkEVMDRPEI 576

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  822 GTQIRSLQSQLQTKES--------EVLEGAERMKdisKEME-ELSQALSQKELEIAQMdqllleKKKDVETLQQTIQEkd 892
Cdd:PLN03229  577 KEKMEALKAEVASSGAssgdelddDLKEKVEKMK---KEIElELAGVLKSMGLEVIGV------TKKNKDTAEQTPPP-- 645

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  893 qqvtelsfSMTEKMVQLNEEkfsLGVEIKTLKEQLSLLSRAEGAKkeqVEDSGAESSPKHGPHESSaqepvckDALQQEL 972
Cdd:PLN03229  646 --------NLQEKIESLNEE---INKKIERVIRSSDLKSKIELLK---LEVAKASKTPDVTEKEKI-------EALEQQI 704

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564376925  973 ewlrkeseqrKRKLQAALISrKELLQKVSKLEEELAKVREESTKDSLRESEKRELEEDSKN 1033
Cdd:PLN03229  705 ----------KQKIAEALNS-SELKEKFEELEAELAAARETAAESNGSLKNDDDKEEDSKE 754
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
847-1229 2.66e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 2.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  847 KDISKEMEELSQALSQKEleiaQMDQLLLEKKKDVETLQQTIQEKDQQVTELS--FSMTEKMVQLNEEKFSLGVEIKTLK 924
Cdd:PRK03918  172 KEIKRRIERLEKFIKRTE----NIEELIKEKEKELEEVLREINEISSELPELReeLEKLEKEVKELEELKEEIEELEKEL 247

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  925 EQLSLLSRAEGAKKEQVEDSGAESSPKHGPHESSAQEpvckdalQQELEWLRKESEQRKRKLQAALISRKELLQKVSKLE 1004
Cdd:PRK03918  248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE-------LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLE 320

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1005 EELAKVREESTKdslRESEKRELEEDSKNKDDPEKygtsEWRELEVSLRL--TISEKEVELEGIRRDLKEKAAAEeelqa 1082
Cdd:PRK03918  321 EEINGIEERIKE---LEEKEERLEELKKKLKELEK----RLEELEERHELyeEAKAKKEELERLKKRLTGLTPEK----- 388

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1083 lVQRMTQDLQNKTKQIDLLQEEITENQATIQKFITGTMDA------GDGDSAVKETSVSSPPRAGGGEHWKPEL------ 1150
Cdd:PRK03918  389 -LEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAieelkkAKGKCPVCGRELTEEHRKELLEEYTAELkrieke 467

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1151 ----EGKIVDLEKEKTQLQKKL--QEALISRKAILKKAQEKEKHLK----EELKEQKDAYRHLQEQFDGQSKENENIAAR 1220
Cdd:PRK03918  468 lkeiEEKERKLRKELRELEKVLkkESELIKLKELAEQLKELEEKLKkynlEELEKKAEEYEKLKEKLIKLKGEIKSLKKE 547


                  ....*....
gi 564376925 1221 LRQLQAKES 1229
Cdd:PRK03918  548 LEKLEELKK 556
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
248-435 2.79e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 2.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  248 TQSDVETEVQQK--LRVMQRKLEEHEEALlGRAQVVDLLQKELTS--AEQRNQDLSQQLQLLEAEHSTLrntmEAERQES 323
Cdd:COG4913   240 AHEALEDAREQIelLEPIRELAERYAAAR-ERLAELEYLRAALRLwfAQRRLELLEAELEELRAELARL----EAELERL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  324 KILMEKVELEMAERKEELYQLQGQ-LERAGQAQAELEMQYGTLQQRHEtEMEEKTACISLLQKNE----QELQSACDALK 398
Cdd:COG4913   315 EARLDALREELDELEAQIRGNGGDrLEQLEREIERLERELEERERRRA-RLEALLAALGLPLPASaeefAALRAEAAALL 393

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 564376925  399 EENSKLLQEQQEQAAKSAQALQQLEDELQQKSKEISQ 435
Cdd:COG4913   394 EALEEELEALEEALAEAEAALRDLRRELRELEAEIAS 430
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1327-2003 2.86e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 43.42  E-value: 2.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1327 QGLEIQNLKAASHEAKAHTEQLKQELESSQLKIADLEHLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTE 1406
Cdd:TIGR00618  151 QGEFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKH 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1407 MEEQERLIKALHTQLEMQAKEHEER------LKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALIS------RKEAL 1474
Cdd:TIGR00618  231 LREALQQTQQSHAYLTQKREAQEEQlkkqqlLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIkavtqiEQQAQ 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1475 KENKSLQEQLSSARDAVEHLTKSLADvESQVSVQNQEKDALLGKLALLQEERDK---LIVEMDKSLLENQSLGGSCESLK 1551
Cdd:TIGR00618  311 RIHTELQSKMRSRAKLLMKRAAHVKQ-QSSIEEQRRLLQTLHSQEIHIRDAHEVatsIREISCQQHTLTQHIHTLQQQKT 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1552 LALGGLTEDKEKLMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSyENVSNEAERIQHVVESVRQEKQEVyAKLRSA 1631
Cdd:TIGR00618  390 TLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQ-RYAELCAAAITCTAQCEKLEKIHL-QESAQS 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1632 ESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPV---GGANESMEALLSSNASLKEELERI 1708
Cdd:TIGR00618  468 LKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIdnpGPLTRRMQRGEQTYAQLETSEEDV 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1709 TLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEA--------QELKQASLETTEKSDEPKDVIEEVTEAVVGKSQEQDSL 1780
Cdd:TIGR00618  548 YHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRskedipnlQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDL 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1781 SENAKLED--AEATLLANSAKPGVSETFSSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKD 1858
Cdd:TIGR00618  628 QDVRLHLQqcSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLR 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1859 SELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNL 1938
Cdd:TIGR00618  708 ELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEI 787

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564376925  1939 KRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPGSKIHAKELQELLKEKQQEVKQLQK 2003
Cdd:TIGR00618  788 QFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLL 852
mukB PRK04863
chromosome partition protein MukB;
1669-1965 3.12e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.41  E-value: 3.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1669 ELEEENDRLRAEAQPVGGANESMEALlssnaslKEELERITLEYKTLSKEF----EALMAEKNTLSEETRNLKLQVEAQE 1744
Cdd:PRK04863  356 DLEELEERLEEQNEVVEEADEQQEEN-------EARAEAAEEEVDELKSQLadyqQALDVQQTRAIQYQQAVQALERAKQ 428

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1745 LKQASLETTEKSD----EPKDVIEEVTEAVVGKSQeQDSLSENAKLEDAEATLLANSAKPGVS---------ETFSSHDD 1811
Cdd:PRK04863  429 LCGLPDLTADNAEdwleEFQAKEQEATEELLSLEQ-KLSVAQAAHSQFEQAYQLVRKIAGEVSrseawdvarELLRRLRE 507

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1812 INNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKET 1891
Cdd:PRK04863  508 QRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQ 587

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564376925 1892 AEEEKDDLEE--RLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRK 1965
Cdd:PRK04863  588 LEQLQARIQRlaARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIER 663
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1314-1481 3.72e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.08  E-value: 3.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1314 SEEVLLLQEQINEQGLEIQNLKAASHEAKAHTEQLKQELESSQLKIADLehlkTLQPELETLQKHVGQKEEEVSYLVGQL 1393
Cdd:COG3206   211 SEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL----LQSPVIQQLRAQLAELEAELAELSARY 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1394 GEKEQTLTTVQTEMEEQERLIKA----LHTQLEMQAKEHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAA--- 1466
Cdd:COG3206   287 TPNHPDVIALRAQIAALRAQLQQeaqrILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVArel 366

                         170
                  ....*....|....*...
gi 564376925 1467 ---LISRKEALKENKSLQ 1481
Cdd:COG3206   367 yesLLQRLEEARLAEALT 384
PRK12704 PRK12704
phosphodiesterase; Provisional
 63-181 3.76e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.84  E-value: 3.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   63 LKDIISKQDAQLQQK-DEALQEEKKGAESKIKKIKLHAKAKITSLNKQIE-ELKTQGGAASPPE---VQAEE-LSKHDKS 136
Cdd:PRK12704   25 RKKIAEAKIKEAEEEaKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEkELRERRNELQKLEkrlLQKEEnLDRKLEL 104

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 564376925  137 STEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSA 181
Cdd:PRK12704  105 LEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISG 149
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1807-2202 3.97e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 3.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1807 SSHDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNA--LLTQISAKDSELKLLEEEVAKINMLNQQIQEELSR 1884
Cdd:COG4717    85 EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLlpLYQELEALEAELAELPERLEELEERLEELRELEEE 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1885 VTKLKETAEEEKDDLEERLMNQLAElngsignYYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIR 1964
Cdd:COG4717   165 LEELEAELAELQEELEELLEQLSLA-------TEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELE 237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1965 KEYMEKiQGAQKGPGSKIHAkelqeLLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAV 2044
Cdd:COG4717   238 AAALEE-RLKEARLLLLIAA-----ALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALP 311

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2045 EHHKKAQAELSSFKI---LLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQK-----------------DEDLLRRL 2104
Cdd:COG4717   312 ALEELEEEELEELLAalgLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEeleqeiaallaeagvedEEELRAAL 391

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2105 EQAEEKH--RKEKKNMQEKLDALHREKAHVED--TLAEIQVSLTRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRDr 2180
Cdd:COG4717   392 EQAEEYQelKEELEELEEQLEELLGELEELLEalDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGE- 470

                         410       420
                  ....*....|....*....|..
gi 564376925 2181 vIDEAKKWEQRFGDAIQTKEEE 2202
Cdd:COG4717   471 -LAELLQELEELKAELRELAEE 491
mukB PRK04863
chromosome partition protein MukB;
127-435 4.08e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 4.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  127 AEELSKHDKSSTEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQASQLDKSSAEMEDFVLMRQKL--QEKEEligalq 204
Cdd:PRK04863  278 ANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALrqQEKIE------ 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  205 tQLSQTQAEQAAQLSSMQQVVREKD---ARFETQVRLHEDELLQLVTQ-SDveteVQQKLRVMQRKLEEHEEA--LLGRA 278
Cdd:PRK04863  352 -RYQADLEELEERLEEQNEVVEEADeqqEENEARAEAAEEEVDELKSQlAD----YQQALDVQQTRAIQYQQAvqALERA 426

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  279 QV-----------VDLLQKELTSAEQRNQDLSQQLQLLEAEHSTLRNTMEAERQESKILMEKVELEMAER--KEELYQLQ 345
Cdd:PRK04863  427 KQlcglpdltadnAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDvaRELLRRLR 506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  346 GQLERAGQAQAeLEMQYGTLQQRHETEMEEKTACISLLQKNEQELQSACD--ALKEENSKLLQEQQEQAAKSAQALQQLE 423
Cdd:PRK04863  507 EQRHLAEQLQQ-LRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDEleQLQEELEARLESLSESVSEARERRMALR 585

                         330
                  ....*....|..
gi 564376925  424 DELQQKSKEISQ 435
Cdd:PRK04863  586 QQLEQLQARIQR 597
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 681-1107 4.08e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 4.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   681 LKTQVLELE---TSLHTAKETHEKNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLYRVKELDvlgelrAQ 757
Cdd:TIGR04523  216 LESQISELKkqnNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELE------KQ 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   758 VRELETSLAEAEKQRGLDYesqraqHNLLTEQIhslsieaKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKES 837
Cdd:TIGR04523  290 LNQLKSEISDLNNQKEQDW------NKELKSEL-------KNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSES 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   838 EVLEGAERM-------KDISKEMEELSQALSQKELEIAQMDQLLLEKKKDVETLQQTIQEKDQQVTELSFSMT---EKMV 907
Cdd:TIGR04523  357 ENSEKQRELeekqneiEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIErlkETII 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   908 QLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAESspkhgphessaqepvckDALQQELEWLRKESEQRKRKLQ 987
Cdd:TIGR04523  437 KNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSI-----------------NKIKQNLEQKQKELKSKEKELK 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   988 AALISRKELLQKVSKLEEELAKVREESTKDSLRESEKrELEEDSKNKDDPEKYGTSEWRELEVSlrltISEKEVELEGIR 1067
Cdd:TIGR04523  500 KLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEK-ESKISDLEDELNKDDFELKKENLEKE----IDEKNKEIEELK 574

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 564376925  1068 RDLKEKAAAEEELQALVQRMTQDLQNKTKQIDLLQEEITE 1107
Cdd:TIGR04523  575 QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISS 614
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 967-1535 4.38e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.90  E-value: 4.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   967 ALQQELEWLRKESEQRKRKLQAALIS-RKELLQKVSKLEEELAKVREESTKDslrESEKRELEEDSK--NKDDPEKYGTS 1043
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTlDDQWKEKRDELNGELSAADAAVAKD---RSELEALEDQHGafLDADIETAAAD 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1044 EWRELEVSLRLTISEKEVE-LEGIRRDLKEK-----AAAEEELQALVQRMTQDLQNKTKQIDLLQEEITENQATIQKFIT 1117
Cdd:pfam12128  346 QEQLPSWQSELENLEERLKaLTGKHQDVTAKynrrrSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELR 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1118 GTMDAGDGDSAVKETSVSSP--------PRAGGGEHWKPELEGKIVDLEKEKTQLQK--KLQEALISRKAILKKAQEK-- 1185
Cdd:pfam12128  426 EQLEAGKLEFNEEEYRLKSRlgelklrlNQATATPELLLQLENFDERIERAREEQEAanAEVERLQSELRQARKRRDQas 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1186 EKHLKEE--LKEQKDAYRHLQEQFDGQSKEN----ENIAARLRQLQAKESTDQQL----------PGTGQQEPTHGSEGL 1249
Cdd:pfam12128  506 EALRQASrrLEERQSALDELELQLFPQAGTLlhflRKEAPDWEQSIGKVISPELLhrtdldpevwDGSVGGELNLYGVKL 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1250 SLEGTEPASESDLHAAQPSHPGE-TATLQATVSVAQIQDQLKEIEVEKEELELKISSTTSELTKKSEEVLllQEQINEQG 1328
Cdd:pfam12128  586 DLKRIDVPEWAASEEELRERLDKaEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDL--RRLFDEKQ 663

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1329 LEIQNLKAASHEAKAHTEQLKQELESsQLKIADLEHLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTL-TTVQTEM 1407
Cdd:pfam12128  664 SEKDKKNKALAERKDSANERLNSLEA-QLKQLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLkAAIAARR 742

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1408 EEQERLIKALHTQLEMQAKE---HEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQl 1484
Cdd:pfam12128  743 SGAKAELKALETWYKRDLASlgvDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIER- 821

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 564376925  1485 sSARDAVEHLTKSLADVESQVSVQNQEKDALLGKLALLQEERDKLIVEMDK 1535
Cdd:pfam12128  822 -AISELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSK 871
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1281-1749 4.85e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 4.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1281 SVAQIQDQLKEIEVEKEELELKISSTTSELTKKSEEVLLLQEQINEQGlEIQNLKAASHEAKAHTEQLKQELESSQLKIA 1360
Cdd:PRK03918  239 EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK-ELKEKAEEYIKLSEFYEEYLDELREIEKRLS 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1361 DLEH-LKTLQPELETLQ------KHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERL-----------IKALHTQLE 1422
Cdd:PRK03918  318 RLEEeINGIEERIKELEekeerlEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLkkrltgltpekLEKELEELE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1423 MQAKEHEERLKQVQVEICELKKQPKEL----EEESKAK-------QQLQRKLQAALISR-----KEALKENKSLQEQLSS 1486
Cdd:PRK03918  398 KAKEEIEEEISKITARIGELKKEIKELkkaiEELKKAKgkcpvcgRELTEEHRKELLEEytaelKRIEKELKEIEEKERK 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1487 ARDAVEHLTKSLA----------------DVESQVSVQNQEK-DALLGKLALLQEERDKL---IVEMDKSLLENQSLGGS 1546
Cdd:PRK03918  478 LRKELRELEKVLKkeseliklkelaeqlkELEEKLKKYNLEElEKKAEEYEKLKEKLIKLkgeIKSLKKELEKLEELKKK 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1547 CESLKLALGGLTEDKEKLMKELESVRCSKIAEStewQEKHKELQKEYEVLLqSYENVSNEAERIQHVVESVRQEKQEVYA 1626
Cdd:PRK03918  558 LAELEKKLDELEEELAELLKELEELGFESVEEL---EERLKELEPFYNEYL-ELKDAEKELEREEKELKKLEEELDKAFE 633

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1627 KLRSAESDKREREKQLQDAEQEMEEMKEkmrkfaKSKQQKILELEEENDRLRAEaqpVGGANESMEALLSSNASLKEELE 1706
Cdd:PRK03918  634 ELAETEKRLEELRKELEELEKKYSEEEY------EELREEYLELSRELAGLRAE---LEELEKRREEIKKTLEKLKEELE 704

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|...
gi 564376925 1707 RITlEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQELKQAS 1749
Cdd:PRK03918  705 ERE-KAKKELEKLEKALERVEELREKVKKYKALLKERALSKVG 746
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 30-602 4.99e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.65  E-value: 4.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925    30 EAELPQGSAMELNNSTQKDVLDRLADAEKLVLELKDIISKQdAQLQQKDEALQEEKKGAESKIKKIKL--HAKAKITSLN 107
Cdd:TIGR00618  195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREAL-QQTQQSHAYLTQKREAQEEQLKKQQLlkQLRARIEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   108 KQIEELKTQGGAASPpEVQAEELSKHDKSSTEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEQAS------------- 174
Cdd:TIGR00618  274 AQEAVLEETQERINR-ARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSieeqrrllqtlhs 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   175 -----------------QLDKSSAEMEDFVLMRQKLQEKEELIGALQTQLSQTQAEQAAQLS--SMQQVVREKDARFETQ 235
Cdd:TIGR00618  353 qeihirdahevatsireISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTrtSAFRDLQGQLAHAKKQ 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   236 VRLHEDELLQLVTQSDVETEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQLQLLEAEHSTLRNT 315
Cdd:TIGR00618  433 QELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIH 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   316 MEAERQESKI------LMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQYGTLQQRHE---TEMEEKTACISLLQKN 386
Cdd:TIGR00618  513 PNPARQDIDNpgpltrRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSiltQCDNRSKEDIPNLQNI 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   387 EQELQSACDALKEENSKLLQEQQEQAAK--SAQALQQLEDELQQKSKEISQfvnkpnLEKHETSSQTSLP-DVYNEGVQA 463
Cdd:TIGR00618  593 TVRLQDLTEKLSEAEDMLACEQHALLRKlqPEQDLQDVRLHLQQCSQELAL------KLTALHALQLTLTqERVREHALS 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   464 VMEESVASLQKRVLELENEKGALLLSSLELEELRAENEKLCSRITLLEAQNRAGEAdgmVCEVSTAGIALLNRSDSSTEE 543
Cdd:TIGR00618  667 IRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNE---IENASSSLGSDLAAREDALNQ 743

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925   544 SGQDVLE--------NTFSQKHKELSVLLVEMKEAQEEIAFLKSQLQGKRPEGDYEVLDRKEVQMME 602
Cdd:TIGR00618  744 SLKELMHqartvlkaRTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQ 810
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1389-1532 5.03e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 5.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1389 LVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLE-----MQAKEHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKL 1463
Cdd:COG4913   615 LEAELAELEEELAEAEERLEALEAELDALQERREalqrlAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALEEQL 694

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564376925 1464 QAALISRKEALKENKSLQEQLSSARDAVEHLTKSLADVESQvsVQNQEKDALLGKLALLQEERDKLIVE 1532
Cdd:COG4913   695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDR--LEAAEDLARLELRALLEERFAAALGD 761
PRK12704 PRK12704
phosphodiesterase; Provisional
 2067-2208 5.11e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 5.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2067 EAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRR--LEQAEEKHRKEKKNMQEKLDALHREKAHVEDTLAEI---QV 2141
Cdd:PRK12704   45 EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELeqkQQ 124

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925 2142 SLTRKDKDMKELQQSLDSTLAQLAAFTKsmsslQDDRDRVIDEAKKwEQRFGDAIQTKEEEVRLKEE 2208
Cdd:PRK12704  125 ELEKKEEELEELIEEQLQELERISGLTA-----EEAKEILLEKVEE-EARHEAAVLIKEIEEEAKEE 185
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 55-371 5.16e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.73  E-value: 5.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   55 DAEKLVLELKDIISKQDAQLQQKDEALQ------EEKKGAESKIKKIK--LHAKAKIT-SLNKQIEELKtQGGAASPPEV 125
Cdd:PRK10929   24 DEKQITQELEQAKAAKTPAQAEIVEALQsalnwlEERKGSLERAKQYQqvIDNFPKLSaELRQQLNNER-DEPRSVPPNM 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  126 QAEELSKHDKSSTEEEMEVEKIKHELQEKEKLISNLQAQLDQAQSEqasqldkssaemedfvlMRQKLQEKEELIGAL-- 203
Cdd:PRK10929  103 STDALEQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTE-----------------ARRQLNEIERRLQTLgt 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  204 ------QTQLSQTQAEQAAQlssmqqvvrekdarfetQVRLHEDELLQLVTQSdvetevQQKLRVMQrkleeheeallgr 277
Cdd:PRK10929  166 pntplaQAQLTALQAESAAL-----------------KALVDELELAQLSANN------RQELARLR------------- 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  278 aqvVDLLQKEltsaeqrnqdlsqqLQLLEAEHSTLRNTMEAERQ-ESKILMEKVELeMAERKEEL-------YQLQGQLE 349
Cdd:PRK10929  210 ---SELAKKR--------------SQQLDAYLQALRNQLNSQRQrEAERALESTEL-LAEQSGDLpksivaqFKINRELS 271

                         330       340
                  ....*....|....*....|..
gi 564376925  350 RAGQAQAElEMQYGTLQQRHET 371
Cdd:PRK10929  272 QALNQQAQ-RMDLIASQQRQAA 292
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2555-2746 5.43e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 5.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2555 GSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHE-----EGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQ 2629
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKqlaalERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2630 EELVCVQKEASKKVSEI-----EDKLK-----RELKHLHHNAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDL 2699
Cdd:COG4942    97 AELEAQKEELAELLRALyrlgrQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 564376925 2700 TAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASLKELAQLKGRQD 2746
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2223-2688 5.43e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.80  E-value: 5.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2223 HMEELKITVSRLEHD----KEIWESK----------AQTELQHQQKAYDKLQEENKELMSQLEEAGQLYHDSKNELTKLE 2288
Cdd:pfam15921  318 QLSDLESTVSQLRSElreaKRMYEDKieelekqlvlANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEK 397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2289 SELKSLKDQSTDLKNSLEKCREH--ENNLE----------------GIIKQQEADIQNCKFNCEQ---LETDLTASRELT 2347
Cdd:pfam15921  398 EQNKRLWDRDTGNSITIDHLRREldDRNMEvqrleallkamksecqGQMERQMAAIQGKNESLEKvssLTAQLESTKEML 477

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2348 TRLHDEINVKE----------QKIISLLSGKEEAIQVAIAELHQQHSK---EIKELENL----------------LSQEE 2398
Cdd:pfam15921  478 RKVVEELTAKKmtlessertvSDLTASLQEKERAIEATNAEITKLRSRvdlKLQELQHLknegdhlrnvqteceaLKLQM 557

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2399 EENLTLEEENKRAVEKTNQLTEALETIKKESLEQKAQLDSFVK----SMSSLQDDRDRIVSDYRQLEERHLSVILEKDEL 2474
Cdd:pfam15921  558 AEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINdrrlELQEFKILKDKKDAKIRELEARVSDLELEKVKL 637

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2475 IqdaaaenNKLKEEIRGLRghmdDLNSENAKLDAELIQYRRDLNEVitikdSQQRQLLEAQLQ-QNKELRNECVKLEGRL 2553
Cdd:pfam15921  638 V-------NAGSERLRAVK----DIKQERDQLLNEVKTSRNELNSL-----SEDYEVLKRNFRnKSEEMETTTNKLKMQL 701

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2554 KGSEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTAlhEEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELV 2633
Cdd:pfam15921  702 KSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITA--KRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELS 779

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 564376925  2634 CVQKEASKKVSEIEdKLKRELKHLHHNAGIMRNETETAEERVAELARDLVEMEQK 2688
Cdd:pfam15921  780 TVATEKNKMAGELE-VLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQE 833
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1991-2204 5.53e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 5.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1991 LKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAAR 2070
Cdd:COG3883    18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2071 VLADNLKLKKELQS-------NKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEDTLAEIQVSL 2143
Cdd:COG3883    98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564376925 2144 TRKDKDMKELQQSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWEQRFGDAIQTKEEEVR 2204
Cdd:COG3883   178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1056-1734 5.68e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.40  E-value: 5.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1056 ISEKEVELEGIRRDLKEKAAAEEELQALVQRMTQDLQNKTKQIDL-LQEEITENQATIQKfitgTMDAGDGDSAVKETSV 1134
Cdd:pfam05483   90 IKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSLkLEEEIQENKDLIKE----NNATRHLCNLLKETCA 165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1135 SSPPRAGGGEHWKPELEGKIVDLEKEKT-------QLQKKLQEALISRKAILKKAQEKEKHLKEELKEQKDAYRHLQEQF 1207
Cdd:pfam05483  166 RSAEKTKKYEYEREETRQVYMDLNNNIEkmilafeELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLL 245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1208 DGQSKENENIAARLRQLqAKESTDQ--QLPGTGQQEPTHGSEGLSLEGTEPASESDLHAAQPSHPGETATLQ-----ATV 1280
Cdd:pfam05483  246 LIQITEKENKMKDLTFL-LEESRDKanQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEedlqiATK 324

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1281 SVAQIQDQLKEIEVEKEELELKISSTTSEL--TKKSEEVLLLQEQINEQGLEIQnLKAASHEAKAHTEQLKQELESSQLK 1358
Cdd:pfam05483  325 TICQLTEEKEAQMEELNKAKAAHSFVVTEFeaTTCSLEELLRTEQQRLEKNEDQ-LKIITMELQKKSSELEEMTKFKNNK 403

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1359 IADLEHLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLEMQAKEHEE---RLKQV 1435
Cdd:pfam05483  404 EVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDlktELEKE 483

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1436 QVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSLAD-VESQVSVQNQEKDA 1514
Cdd:pfam05483  484 KLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDeLESVREEFIQKGDE 563

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1515 LLGKLALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTEDKEKLMKELESVRCSKIAESTE---WQEKHKELQK 1591
Cdd:pfam05483  564 VKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQlnaYEIKVNKLEL 643

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1592 EYEVLLQSYENVSNEaerIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELE 1671
Cdd:pfam05483  644 ELASAKQKFEEIIDN---YQKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKII 720

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564376925  1672 EENDrlraeaQPVGGANESMEALLSSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETR 1734
Cdd:pfam05483  721 EERD------SELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAK 777
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2576-2827 5.80e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.22  E-value: 5.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2576 GLSKEIKSFkeqLTALHEEGalaVYHAQLRVREEEVQKLTAALSSSQKrtvdLQEELVCVQKEASKKVSEIEDKLKRELK 2655
Cdd:PRK05771   13 TLKSYKDEV---LEALHELG---VVHIEDLKEELSNERLRKLRSLLTK----LSEALDKLRSYLPKLNPLREEKKKVSVK 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2656 hlhhnagimrnETETA----EERVAELARDLVEMEQKLLTVTKENKDLTAQIQ------AFGKSMSSLQDSR-------- 2717
Cdd:PRK05771   83 -----------SLEELikdvEEELEKIEKEIKELEEEISELENEIKELEQEIErlepwgNFDLDLSLLLGFKyvsvfvgt 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2718 ------DHATEELSDLKKKYDASLKE-----LAQLKGR-QDLGRESDVLSQAAFPLTTSENISSRLEKLNQQLTSKDEQL 2785
Cdd:PRK05771  152 vpedklEELKLESDVENVEYISTDKGyvyvvVVVLKELsDEVEEELKKLGFERLELEEEGTPSELIREIKEELEEIEKER 231

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 564376925 2786 LHLSSELESSHNQVQSFTKAMTS-LQNERDHLwNELEKFRKSE 2827
Cdd:PRK05771  232 ESLLEELKELAKKYLEELLALYEyLEIELERA-EALSKFLKTD 273
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1861-2088 6.21e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 6.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1861 LKLLEEEVAkinmlnqQIQEELSRVTKLKETAEEEKDDLEERLmNQLAELngsignyyQDVTDAQIKNEQLESEmqnlkr 1940
Cdd:COG4913   612 LAALEAELA-------ELEEELAEAEERLEALEAELDALQERR-EALQRL--------AEYSWDEIDVASAERE------ 669

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1941 cVSELEEEKQQLVKEKTKVEseirkeymekiqgaqkgpgskihakELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVK 2020
Cdd:COG4913   670 -IAELEAELERLDASSDDLA-------------------------ALEEQLEELEAELEELEEELDELKGEIGRLEKELE 723

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564376925 2021 ALEFVHTESQKDLDAtkgnLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKES 2088
Cdd:COG4913   724 QAEEELDELQDRLEA----AEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEE 787
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2765-2967 6.34e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 6.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2765 ENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSFTKAMTSLQNERDHLWNELEKFRKSEEGKQRSAAPSAASSPAE 2844
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2845 VQSLKKAMSSLQ--------------NDRDRLLKELKNLQQQYLQMNQEITELRPLKAQLQESQDQTKALQMMKEELRQE 2910
Cdd:COG4942   103 KEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925 2911 NLSWQHELHQLRVEKNSWELHERRMKEQYLMAISDKDQQLGHLQNLLRELRSSSQTQ 2967
Cdd:COG4942   183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1407-2165 6.65e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.41  E-value: 6.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1407 MEEQERLIKALHTQLEMQAKEHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAaliSRKEALKENKSLQEQLSS 1486
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQ---SQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1487 ARDAVEHLtksLADVESQVsvqNQEKDALLGKLALLQEERDKLI---VEMDKSLLENQSLggSCESLKLALGGLTEDKEK 1563
Cdd:pfam15921  157 AKCLKEDM---LEDSNTQI---EQLRKMMLSHEGVLQEIRSILVdfeEASGKKIYEHDSM--STMHFRSLGSAISKILRE 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1564 LMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYEnvsneaERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQ 1643
Cdd:pfam15921  229 LDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLE 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1644 DAEQEMEEMKEKMrkfakskQQKILELEEENDRLRAEaqpvgganesmeaLLSSNASLKEELERITLEYKTLSKEFEALM 1723
Cdd:pfam15921  303 IIQEQARNQNSMY-------MRQLSDLESTVSQLRSE-------------LREAKRMYEDKIEELEKQLVLANSELTEAR 362

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1724 AEKNTLSEETRNL--KLQVEAQELKQASLETTEKSDEPKDVIEEVTeavvGKSQEQDSLSENAKLEDAEATLLANSAKPG 1801
Cdd:pfam15921  363 TERDQFSQESGNLddQLQKLLADLHKREKELSLEKEQNKRLWDRDT----GNSITIDHLRRELDDRNMEVQRLEALLKAM 438

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1802 VSETFSSHDD----INNYLQQLDQLKGRIAELEMEKQKDRELSQ-------TLENEKNALLTQISAKDSELKLLEEEVAK 1870
Cdd:pfam15921  439 KSECQGQMERqmaaIQGKNESLEKVSSLTAQLESTKEMLRKVVEeltakkmTLESSERTVSDLTASLQEKERAIEATNAE 518

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1871 INMLNQQIQEELSRVTKLKETAEE----------------EKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESE 1934
Cdd:pfam15921  519 ITKLRSRVDLKLQELQHLKNEGDHlrnvqtecealklqmaEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKE 598

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1935 MQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGpgskihaKELQELLKEKQQEVKQLQKDCIRYLGRISA 2014
Cdd:pfam15921  599 INDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAG-------SERLRAVKDIKQERDQLLNEVKTSRNELNS 671

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2015 LEKTVKALEFVHTESQKDLDATKGNLAQAVehhKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSqIK 2094
Cdd:pfam15921  672 LSEDYEVLKRNFRNKSEEMETTTNKLKMQL---KSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDA-LQ 747

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564376925  2095 QKDEDLLRRLEQA-EEKH--RKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLA 2165
Cdd:pfam15921  748 SKIQFLEEAMTNAnKEKHflKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFA 821
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1814-2129 7.01e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 7.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1814 NYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDselKLLEEEVAKINMLNQQ--IQEELSRVTKLKET 1891
Cdd:pfam17380  272 NQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRR---KLEEAEKARQAEMDRQaaIYAEQERMAMERER 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1892 A------EEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRcVSELEEEKQQLVKEKTKVESEIRK 1965
Cdd:pfam17380  349 ElerirqEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARK-VKILEEERQRKIQQQKVEMEQIRA 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1966 EYMEKIQgaqkgpgskihaKELQELLKEKQQEVKQLQKDCIRYLGRISALEktvkalefvhtesQKDLDATKGNLAQAVE 2045
Cdd:pfam17380  428 EQEEARQ------------REVRRLEEERAREMERVRLEEQERQQQVERLR-------------QQEEERKRKKLELEKE 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2046 HHKKAQAELSSFKILLDDTQSEAARVLADNLK---LKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNM---- 2118
Cdd:pfam17380  483 KRDRKRAEEQRRKILEKELEERKQAMIEEERKrklLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMrkat 562

                          330
                   ....*....|...
gi 564376925  2119 --QEKLDALHREK 2129
Cdd:pfam17380  563 eeRSRLEAMERER 575
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 82-483 7.35e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 42.26  E-value: 7.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925    82 QEEKKGAESKIKKIKLHAKAKITSLNKQIEELKTQGGAASPPEV---------QAEELSKHDKSSTEEEMEVEKIKHELQ 152
Cdd:TIGR00618  177 QYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERkqvlekelkHLREALQQTQQSHAYLTQKREAQEEQL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   153 EKEKLISNLQAQLDQAQSEQASQLDKSSA-----EMEDFVLMRQKLQEKEELIGALQTQLSQTQAEQAAQLSSMQQVVre 227
Cdd:TIGR00618  257 KKQQLLKQLRARIEELRAQEAVLEETQERinrarKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHV-- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   228 KDARFETQVRLHEDELLQLVTQSDVETEVQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQLQLLEA 307
Cdd:TIGR00618  335 KQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDT 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   308 EHSTLRN------TMEAERQESKILMEKVELEMAERKEELYQLQGQLERAGQAQAELEMQYGTLQQRHETEMEEKT---A 378
Cdd:TIGR00618  415 RTSAFRDlqgqlaHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAvvlA 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   379 CISLLQKNEQELQSACDALKEE---------NSKLLQEQQEQAAKSAQALQQLEDELQQKSKEISQFVNKPNLEKHETSS 449
Cdd:TIGR00618  495 RLLELQEEPCPLCGSCIHPNPArqdidnpgpLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSI 574

                          410       420       430
                   ....*....|....*....|....*....|....
gi 564376925   450 QTSLPDVYNEGVQAVMEESVASLQKRVLELENEK 483
Cdd:TIGR00618  575 LTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAED 608
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1814-2046 8.00e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.84  E-value: 8.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1814 NYLQQLDQLKGRIAELEMEKQKDR--ELSQTLENEKNALLTQISAKDSELKLLEEEVAKinmlnqqIQEELSRVTKLKET 1891
Cdd:PRK05771   60 DKLRSYLPKLNPLREEKKKVSVKSleELIKDVEEELEKIEKEIKELEEEISELENEIKE-------LEQEIERLEPWGNF 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1892 AEEEKDDLEERlmnqlaelngsignyYQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQ--------LVKEKTKVESEI 1963
Cdd:PRK05771  133 DLDLSLLLGFK---------------YVSVFVGTVPEDKLEELKLESDVENVEYISTDKGyvyvvvvvLKELSDEVEEEL 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1964 RKEYMEKIQGAQKGpgskihakELQELLKEKQQEVKQLQKDcirylgrisaLEKTVKALEFVHTESQKDLDATKGNLAQA 2043
Cdd:PRK05771  198 KKLGFERLELEEEG--------TPSELIREIKEELEEIEKE----------RESLLEELKELAKKYLEELLALYEYLEIE 259


                  ...
gi 564376925 2044 VEH 2046
Cdd:PRK05771  260 LER 262
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1353-2297 8.10e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 8.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1353 ESSQLKIADLEHLKTLQPELETLQKHVGQKEEEVSYLVGQLGEKEQTLTTVQTEMEEQERLIKALHTQLE-----MQAK- 1426
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEeilheLESRl 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1427 -EHEERLKQVQVEICELKKQPKELEEESKAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVEHLTKSLADVESQV 1505
Cdd:pfam01576   85 eEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEF 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1506 SVQNQEKDALLGKLALLQEERDKLIVEMDKSLlenqslggsceslklalggltEDKEKLMKELESVRCSKIAESTEWQEK 1585
Cdd:pfam01576  165 TSNLAEEEEKAKSLSKLKNKHEAMISDLEERL---------------------KKEEKGRQELEKAKRKLEGESTDLQEQ 223

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1586 HKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQ 1665
Cdd:pfam01576  224 IAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEA 303

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1666 KILELEEENDRLRAEA-------QPVGGANESMEALLSSN-ASLKEELERITLEYKTLSKEFEALM-----AEKNTLSEE 1732
Cdd:pfam01576  304 LKTELEDTLDTTAAQQelrskreQEVTELKKALEEETRSHeAQLQEMRQKHTQALEELTEQLEQAKrnkanLEKAKQALE 383

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1733 TRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLLANSAKPGVSETFSSHDDI 1812
Cdd:pfam01576  384 SENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDV 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1813 NNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEKNALLTQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETA 1892
Cdd:pfam01576  464 SSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAL 543

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1893 EEEKDDLE---ERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMQNLKRCVSELE-----------EEKQ---QLVKE 1955
Cdd:pfam01576  544 EEGKKRLQrelEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEkkqkkfdqmlaEEKAisaRYAEE 623

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1956 KTKVESEIRKEYMEKIQGAQKGPGSKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVKALEFVHTESQKDLDA 2035
Cdd:pfam01576  624 RDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEE 703

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2036 TKGNLA-----------------------------QAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNK 2086
Cdd:pfam01576  704 LEDELQatedaklrlevnmqalkaqferdlqardeQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELE 783

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2087 ESIKSQIKQKDEDLlrrleqaeekhrKEKKNMQEKLDALHREKAHVEDTLAEIQVSLTRKDKDMKELQQSLDSTLAQLAA 2166
Cdd:pfam01576  784 AQIDAANKGREEAV------------KQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAA 851

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2167 FTKSMSSLQDDRDRVIDEAKKW----------EQRFGDAIQTKEEEVRLKEENCTALKDQLRQMTIHMEELKITVsrleh 2236
Cdd:pfam01576  852 SERARRQAQQERDELADEIASGasgksalqdeKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTEL----- 926

                          970       980       990      1000      1010      1020
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564376925  2237 dkeiweSKAQTELQHQQKAYDKLQEENKELMSQL-EEAGQLYHDSKNELTKLESELKSLKDQ 2297
Cdd:pfam01576  927 ------AAERSTSQKSESARQQLERQNKELKAKLqEMEGTVKSKFKSSIAALEAKIAQLEEQ 982
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 199-435 8.28e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 8.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  199 LIGALQTQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQSDVETEVQQKLRVMQRKLEEHEEALLGRA 278
Cdd:COG4942    10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  279 QVVDLLQKELtSAEQRNQDLSQQLQLLEAEHSTLRNTMEAER-QESKILMEKVELEMAERKEELYQLQGQLERAGQAQAE 357
Cdd:COG4942    90 KEIAELRAEL-EAQKEELAELLRALYRLGRQPPLALLLSPEDfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564376925  358 LEMQYGTLQQRHETEMEEKTACISLLQKNEQELQSAcdalkEENSKLLQEQQEQAAKSAQALQQLEDELQQKSKEISQ 435
Cdd:COG4942   169 LEAERAELEALLAELEEERAALEALKAERQKLLARL-----EKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
675-1115 8.69e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 8.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  675 QGELERLKTQVLELETSLHTAKETHE---------KNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERDQLLYRV 745
Cdd:PRK03918  251 EGSKRKLEEKIRELEERIEELKKEIEeleekvkelKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERI 330

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  746 KELDvlgELRAQVRELETSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIETLQRELDG-------VQLQF 818
Cdd:PRK03918  331 KELE---EKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEElekakeeIEEEI 407

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  819 SEQGTQIRSLQSQLQTKESEV--LEGAER------------------------MKDISKEMEELSQALSQKELEIAQMDQ 872
Cdd:PRK03918  408 SKITARIGELKKEIKELKKAIeeLKKAKGkcpvcgrelteehrkelleeytaeLKRIEKELKEIEEKERKLRKELRELEK 487

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  873 LLLEKKKdVETLQQTIQEKDQQVTELSFSMTEKMVQ-------LNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSG 945
Cdd:PRK03918  488 VLKKESE-LIKLKELAEQLKELEEKLKKYNLEELEKkaeeyekLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLD 566

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  946 -AESSPKHGPHESSAQEPVCKDALQQELEWLRKESEqRKRKLQAALISRKELLQKVSKLEEELAKVREESTKDSLRESEK 1024
Cdd:PRK03918  567 eLEEELAELLKELEELGFESVEELEERLKELEPFYN-EYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEEL 645

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1025 RELEEDSKNKDDPEKYgtSEWRELEVSLRLTISEKEVELEGIRRDLKEKAAAEEELQALVQRMtqdlQNKTKQIDLLQEE 1104
Cdd:PRK03918  646 RKELEELEKKYSEEEY--EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER----EKAKKELEKLEKA 719

                         490
                  ....*....|.
gi 564376925 1105 ITENQATIQKF 1115
Cdd:PRK03918  720 LERVEELREKV 730
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
143-366 8.74e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 8.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  143 EVEKIKHELQEKEKLISNLQAQldqaqseqasqldkssaemEDFVLMRQKLQEKEELIGALQTQLSQTQAEQAAQLSSMQ 222
Cdd:COG3206   183 QLPELRKELEEAEAALEEFRQK-------------------NGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLA 243

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  223 QVVREKDARFETQVRLHEDELLQLVTQSDVETEvQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQDLSQQL 302
Cdd:COG3206   244 ALRAQLGSGPDALPELLQSPVIQQLRAQLAELE-AELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAEL 322

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564376925  303 QLLEAEHSTLRNTMEAERQESKILMEK-VELEMAERKEELYQ--LQGQLERAGQAQAELEMQYGTLQ 366
Cdd:COG3206   323 EALQAREASLQAQLAQLEARLAELPELeAELRRLEREVEVARelYESLLQRLEEARLAEALTVGNVR 389
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1482-2199 9.03e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.75  E-value: 9.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1482 EQLSSARDAVEHLTKSLADVESQVSVQNQEKDALLGKL-ALLQEERDKLIVEMDKSLLENQSLGGSCESLKLALGGLTED 1560
Cdd:pfam12128  251 NTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELnQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQ 330

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1561 KEKLMKELESVRCSKIAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEVYAKLRSAESDKREREK 1640
Cdd:pfam12128  331 HGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQL 410

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1641 QLQDAEQEM------EEMKEKMRKFAKSKQQKILELEEENDRLrAEAQPVGGANESMEALLSSNASLKEELERITLEYKT 1714
Cdd:pfam12128  411 AVAEDDLQAleselrEQLEAGKLEFNEEEYRLKSRLGELKLRL-NQATATPELLLQLENFDERIERAREEQEAANAEVER 489

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1715 LSKEFEALMAEKNTLSEETRNLKLQVEAQELKQASLETtEKSDEPKDVIEEVTEAVVGKSQEQDSLSENAKLEDAEATLL 1794
Cdd:pfam12128  490 LQSELRQARKRRDQASEALRQASRRLEERQSALDELEL-QLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPE 568

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1795 ANSAKPGVSETFSS------HDDINNYLQQLDQLKGRIAELEMEKQKDRELSQTLENEknalLTQISAKDSELKLLEEEV 1868
Cdd:pfam12128  569 VWDGSVGGELNLYGvkldlkRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQ----LVQANGELEKASREETFA 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1869 A---KINMLNQQ--IQEELSRVTKLKETAEEEKDDLEERLMNQLAELNgSIGNYYQDVTdAQIKNEQLESEMQNLkrcvs 1943
Cdd:pfam12128  645 RtalKNARLDLRrlFDEKQSEKDKKNKALAERKDSANERLNSLEAQLK-QLDKKHQAWL-EEQKEQKREARTEKQ----- 717

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1944 eleeEKQQLVKEKTKVESEIRKEYMEKIQGAqkgpgskiHAKELQELLKEKQQEVKQLQKDCIrylgRISALEKTVKale 2023
Cdd:pfam12128  718 ----AYWQVVEGALDAQLALLKAAIAARRSG--------AKAELKALETWYKRDLASLGVDPD----VIAKLKREIR--- 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2024 fvhtesqkdldatkgNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNLklkKELQSNKESIKSQIKQKDEDLLRR 2103
Cdd:pfam12128  779 ---------------TLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQL---SNIERAISELQQQLARLIADTKLR 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2104 LeQAEEKHRKEKKNMQEKLDALHREKAHVEDTLAEIQVsltrkDKDMKELQQSLDSTLAQLaaftksmSSLQDDRDRVID 2183
Cdd:pfam12128  841 R-AKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKE-----DANSEQAQGSIGERLAQL-------EDLKLKRDYLSE 907

                          730
                   ....*....|....*.
gi 564376925  2184 EAKKWEQRFGDAIQTK 2199
Cdd:pfam12128  908 SVKKYVEHFKNVIADH 923
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1834-2362 9.21e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.96  E-value: 9.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1834 QKDRELSQTLENEKNALLtQISAKDSELKLLEEEVAKINMLNQQIQEELSRVTKLKETAEEEKDDLEERL---------M 1904
Cdd:TIGR01612 1946 EKEPEIYTKIRDSYDTLL-DIFKKSQDLHKKEQDTLNIIFENQQLYEKIQASNELKDTLSDLKYKKEKILndvklllhkF 2024

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1905 NQLAELNGSIGNY-------YQDVTDAQIKNEQLESEMQNLKRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKG 1977
Cdd:TIGR01612 2025 DELNKLSCDSQNYdtilelsKQDKIKEKIDNYEKEKEKFGIDFDVKAMEEKFDNDIKDIEKFENNYKHSEKDNHDFSEEK 2104

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1978 PGSKIHAKELQELLKEKQQEVKQLQKDCIRYLGRISALEKTVK-ALEFVHTESQKDLDATKGNLAQAVEHHKKAQAELss 2056
Cdd:TIGR01612 2105 DNIIQSKKKLKELTEAFNTEIKIIEDKIIEKNDLIDKLIEMRKeCLLFSYATLVETLKSKVINHSEFITSAAKFSKDF-- 2182

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2057 FKILLDDTQSEAARVlaDNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQaeEKHRKEKKNMQEKL----------DALH 2126
Cdd:TIGR01612 2183 FEFIEDISDSLNDDI--DALQIKYNLNQTKKHMISILADATKDHNNLIEK--EKEATKIINNLTELftidfnnadaDILH 2258

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2127 REKAHVEDTLAEIQVS------LTRKDKDMK------------ELQQSLDSTLA-QLAAFTKSMSSLQDDRDRVIDEAKK 2187
Cdd:TIGR01612 2259 NNKIQIIYFNSELHKSiesikkLYKKINAFKllnishinekyfDISKEFDNIIQlQKHKLTENLNDLKEIDQYISDKKNI 2338

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2188 WEQRFG--------------DAIQTKE------EEVRLKE-ENCTALKDQLRQMTIHMEELKITVSRLEHDKEIWE---- 2242
Cdd:TIGR01612 2339 FLHALNentnfnfnalkeiyDDIINREnkadeiENINNKEnENIMQYIDTITKLTEKIQDILIFVTTYENDNNIIKqhiq 2418

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2243 -------SKAQTELQHQQKAYDKLQEENKELMSQ----------LEEAGQLYHDSKNELTK---LESELKSLKDQSTDLK 2302
Cdd:TIGR01612 2419 dndendvSKIKDNLKKTIQSFQEILNKIDEIKAQfyggnninniIITISQNANDVKNHFSKdltIENELIQIQKRLEDIK 2498

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564376925  2303 NSLEKCREHE-----NNLEGIIKQQEADIQNCKFNCEQLE-TDLTASRELTTRLHDEINVKEQKII 2362
Cdd:TIGR01612 2499 NAAHEIRSEQitkytNAIHNHIEEQFKKIENNSNKDEVYKiNEIDNIIEKIINYNKEPEVKLHAII 2564
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1661-2799 9.21e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 41.96  E-value: 9.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1661 KSKQQKILELEEEN-DRLRAEAQPVGGANESMEA------LLSSNASLKEELERIT--LEYKTLSKEFEALMAEKNT-LS 1730
Cdd:TIGR01612  558 KLIHEIKKELEEENeDSIHLEKEIKDLFDKYLEIddeiiyINKLKLELKEKIKNISdkNEYIKKAIDLKKIIENNNAyID 637

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1731 EETRNLKLQVEAQELKQASLETTEKSDEPK---DVIEEVTEAVVGKSQEQ--DSLSENAKLEDAEATLLANSAKPGVSET 1805
Cdd:TIGR01612  638 ELAKISPYQVPEHLKNKDKIYSTIKSELSKiyeDDIDALYNELSSIVKENaiDNTEDKAKLDDLKSKIDKEYDKIQNMET 717

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1806 FSSHDDINNYLQQLDQLKGRIAELE--MEKQKDRELSQTLENEKNA---LLTQISAKDSELKLLEEEVAKINMLNQQIQE 1880
Cdd:TIGR01612  718 ATVELHLSNIENKKNELLDIIVEIKkhIHGEINKDLNKILEDFKNKekeLSNKINDYAKEKDELNKYKSKISEIKNHYND 797

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1881 ELSRVTKLKETAEEEKDDLEErlmnqlaelngsignYYQDVTDAQIKNEQLESEMQNLK---------------RCVSEL 1945
Cdd:TIGR01612  798 QINIDNIKDEDAKQNYDKSKE---------------YIKTISIKEDEIFKIINEMKFMKddflnkvdkfinfenNCKEKI 862

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  1946 EEEKQQLVKEKTKVESEIRKEYMEKIQgaQKGPGSKIHAKELQELLKEKQQEVKQLQKdcirYLGRISALEKTVKALEFV 2025
Cdd:TIGR01612  863 DSEHEQFAELTNKIKAEISDDKLNDYE--KKFNDSKSLINEINKSIEEEYQNINTLKK----VDEYIKICENTKESIEKF 936

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2026 HTESQKDLDATKGNLAQAVEHHKKAQAELSSFKILLDDTQSEAARVLADNL----------------KLKKELQSNKESI 2089
Cdd:TIGR01612  937 HNKQNILKEILNKNIDTIKESNLIEKSYKDKFDNTLIDKINELDKAFKDASlndyeaknnelikyfnDLKANLGKNKENM 1016

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2090 KSQIKQKDEDLLRRLEQAEEKHRKEKKNMQ--------------EKLDALHREKAHVEdTLAEIQVSLTRKDKDMKELQq 2155
Cdd:TIGR01612 1017 LYHQFDEKEKATNDIEQKIEDANKNIPNIEiaihtsiyniideiEKEIGKNIELLNKE-ILEEAEINITNFNEIKEKLK- 1094

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2156 sldstLAQLAAFTKSMS-SLQDDRDRVIDEAKKWEQRFGDAIQTKEEEVRLKEENCTALKDQLRQM------TIHMEELK 2228
Cdd:TIGR01612 1095 -----HYNFDDFGKEENiKYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLedvadkAISNDDPE 1169

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2229 -------ITVSRLEHDKEIWE--SKAQTELQHQQKAYDKLQEENKELMSQLEEAGQLYHDS-KNELTKLESELKSLKDQS 2298
Cdd:TIGR01612 1170 eiekkieNIVTKIDKKKNIYDeiKKLLNEIAEIEKDKTSLEEVKGINLSYGKNLGKLFLEKiDEEKKKSEHMIKAMEAYI 1249

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2299 TDLKNSLEKCREHENNLegiikQQEADIqNCKFNCEQLETDLTASRELTTRLHDE----INVKEQKIISLLSGK------ 2368
Cdd:TIGR01612 1250 EDLDEIKEKSPEIENEM-----GIEMDI-KAEMETFNISHDDDKDHHIISKKHDEnisdIREKSLKIIEDFSEEsdindi 1323

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2369 EEAIQVAIAElHQQHSKEIKELENLLSQEEEENLTLEEEN--KRAVEKTNQLTEALETIKKEsLEQKAQLDSFVKSMSSL 2446
Cdd:TIGR01612 1324 KKELQKNLLD-AQKHNSDINLYLNEIANIYNILKLNKIKKiiDEVKEYTKEIEENNKNIKDE-LDKSEKLIKKIKDDINL 1401

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2447 QDDRDRIVS--DYRQLEERHLSVILEKDELIQDA---------AAENNKLK-------EEIRGLRGHMDDLNSENAKLDA 2508
Cdd:TIGR01612 1402 EECKSKIEStlDDKDIDECIKKIKELKNHILSEEsnidtyfknADENNENVlllfkniEMADNKSQHILKIKKDNATNDH 1481

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2509 ELiqyrrDLNEVITIKDSQQRQLLEA-----QLQQNKELRNECVKLEGRL--KGSEAEkqsLQMSLDALQEENQGLSKEI 2581
Cdd:TIGR01612 1482 DF-----NINELKEHIDKSKGCKDEAdknakAIEKNKELFEQYKKDVTELlnKYSALA---IKNKFAKTKKDSEIIIKEI 1553

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2582 KSFKEQLT---ALHEEGALAVYHAQLRVREEevqklTAALSSSQKRTVDLQEELVCVQKEAsKKVSEIEDKLKRELKhlh 2658
Cdd:TIGR01612 1554 KDAHKKFIleaEKSEQKIKEIKKEKFRIEDD-----AAKNDKSNKAAIDIQLSLENFENKF-LKISDIKKKINDCLK--- 1624

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2659 hnagimrnETETAEERVAELARDLVEMEqklltvTKENKDLTAQIQAFGKSMSSLQDSRDHATEELSDLKKKYDASLKEL 2738
Cdd:TIGR01612 1625 --------ETESIEKKISSFSIDSQDTE------LKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDV 1690

                         1210      1220      1230      1240      1250      1260
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564376925  2739 AQLKGRQDLG-----RESDVLSQAAFPlTTSENISSRLEKLNQQLTSKDEQLLHLSSELESSHNQV 2799
Cdd:TIGR01612 1691 DQHKKNYEIGiiekiKEIAIANKEEIE-SIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEI 1755
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 677-870 9.30e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 41.21  E-value: 9.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   677 ELERLKTQVLELETSLHTAKETHEKNLSEKAKEISSLTQLTKEFKESAEEARSTLTAVCEERdqllyrvkelDVLGELRA 756
Cdd:pfam19220   42 ELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALREAE----------AAKEELRI 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925   757 QVRELETSLAEAEKQrgLDYESQRAQHnlLTEQIHSLSIEAKSKDVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKE 836
Cdd:pfam19220  112 ELRDKTAQAEALERQ--LAAETEQNRA--LEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQALSEEQA 187

                          170       180       190
                   ....*....|....*....|....*....|....
gi 564376925   837 SEVLEGAERMKDISKEMEELSQALSQKELEIAQM 870
Cdd:pfam19220  188 AELAELTRRLAELETQLDATRARLRALEGQLAAE 221
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2770-3038 9.38e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 9.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2770 RLEKLNQQLTSKDEQLLHLSSELESSHNQVQSFTKAMTSLQNERDHLWNELEKFRKSEEGKQRSAAPSAASSPAEVQSLK 2849
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2850 KAMSSLQND---RDRLLKELKNLQQQYLQMNQEITELRplkAQLQESQDQTKALQMMKEELRQENLSWQHELHQLRVEKN 2926
Cdd:TIGR02168  320 ELEAQLEELeskLDELAEELAELEEKLEELKEELESLE---AELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  2927 SWELHERRMKEQylmaisdKDQQLGHLQNLLRELRSSSQTQILPtqyQRQASSGTSAALD-GSQNLVYETDCLRTQLNDS 3005
Cdd:TIGR02168  397 SLNNEIERLEAR-------LERLEDRRERLQQEIEELLKKLEEA---ELKELQAELEELEeELEELQEELERLEEALEEL 466

                          250       260       270
                   ....*....|....*....|....*....|...
gi 564376925  3006 LKEIHQKELRIQQLNSKFSQLLEEKNILSTQLR 3038
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDSLERLQE 499
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
705-1226 9.47e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 9.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  705 EKAKE-ISSLTQLtKEFKESAEEARSTLTAVCEERDQLLYRVKEL------DVLGELRAQVRELETSLAEAEKQRgldyE 777
Cdd:COG4913   245 EDAREqIELLEPI-RELAERYAAARERLAELEYLRAALRLWFAQRrlelleAELEELRAELARLEAELERLEARL----D 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  778 SQRAQHNLLTEQIHSLSIEAKSK-DVKIETLQRELDGVQLQFSEQGTQIRSLQSQLQTKESEVLEGAERMKDISKEMEEL 856
Cdd:COG4913   320 ALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEE 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  857 SQALSQkelEIAQMDQLLLEKKKDVETLQQTIQE---------------KDQQVTELSFSMTE-----KMVQLNEE---- 912
Cdd:COG4913   400 LEALEE---ALAEAEAALRDLRRELRELEAEIASlerrksniparllalRDALAEALGLDEAElpfvgELIEVRPEeerw 476

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  913 -----------KFSLGVEIKTLKE--------QLSLLSRAEGAKKEQVEDSGAESSPKHGPHESSAQEPVCKDALQQELE 973
Cdd:COG4913   477 rgaiervlggfALTLLVPPEHYAAalrwvnrlHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELG 556

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  974 W------------------------LRKESEQRKRKLQAALISRKELL-----QKVSKLEEELAKVREESTK-DSLRESE 1023
Cdd:COG4913   557 RrfdyvcvdspeelrrhpraitragQVKGNGTRHEKDDRRRIRSRYVLgfdnrAKLAALEAELAELEEELAEaEERLEAL 636

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1024 KRELEEDSKNKDDPEKYGTSEWRELEV-SLRLTISEKEVELEGIRR---DLKEKAAAEEELQALVQRMTQDLQNKTKQID 1099
Cdd:COG4913   637 EAELDALQERREALQRLAEYSWDEIDVaSAEREIAELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIG 716

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1100 LLQEEITENQATIQKFITGTMDAGDGdsavketsVSSPPRAGGGEHWKPELEGKIVDlekektQLQKKLQEaliSRKAIL 1179
Cdd:COG4913   717 RLEKELEQAEEELDELQDRLEAAEDL--------ARLELRALLEERFAAALGDAVER------ELRENLEE---RIDALR 779

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*..
gi 564376925 1180 KKAQEKEKHLKEELKEQKDAYRHLQEQFDGQSKENENIAARLRQLQA 1226
Cdd:COG4913   780 ARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEE 826
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2476-2687 9.60e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 9.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2476 QDAAAENNKLKEEIRGLRGHMDDLNSENAKLDAELIQYRRDLNEVITikdSQQRQLLEAQLQQNkelrnecvklegrlkg 2555
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDL---SEEAKLLLQQLSEL---------------- 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 2556 sEAEKQSLQMSLDALQEENQGLSKEIKSFKEQLTALHEEGALAVYHAQLRVREEEVQKLTAALSSSQKRTVDLQEELVCV 2635
Cdd:COG3206   225 -ESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAAL 303

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 564376925 2636 QKEASKKVSEIEDKLKRELKHLHHNAGIMRNETETAEERVAELARDLVEMEQ 2687
Cdd:COG3206   304 RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
836-1086 9.63e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 9.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  836 ESEVLEGAERMKDiskEMEELSQALSQKELEIAQMDQL--LLEKKKDVETLQQTIQEKDQQVTELSF--------SMTEK 905
Cdd:COG4913   220 EPDTFEAADALVE---HFDDLERAHEALEDAREQIELLepIRELAERYAAARERLAELEYLRAALRLwfaqrrleLLEAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  906 MVQLNEEKFSLGVEIKTLKEQLSLLSRAEGAKKEQVEDSGAESspkhgphessaqepvcKDALQQELEWLRKESEQRKRK 985
Cdd:COG4913   297 LEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDR----------------LEQLEREIERLERELEERERR 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925  986 lqaalisRKELLQKVSKLEEELAKVREESTKdsLRESEKRELEedsknkddpekygtsEWRELEVSLRLTISEKEVELEG 1065
Cdd:COG4913   361 -------RARLEALLAALGLPLPASAEEFAA--LRAEAAALLE---------------ALEEELEALEEALAEAEAALRD 416

                         250       260
                  ....*....|....*....|.
gi 564376925 1066 IRRDLKEKaaaEEELQALVQR 1086
Cdd:COG4913   417 LRRELREL---EAEIASLERR 434
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1691-1916 9.93e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.54  E-value: 9.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1691 MEALLSSNASLKEELERITLEYKTLSKEFEALMAEKNTLSEETRNLKLQVEAQELKQASLETTEKSDEPKDVIEEVTEAV 1770
Cdd:COG3206   170 REEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQL 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564376925 1771 VGKSQEQDSLSENAKLEDAEATLLANSAK-PGVSETFS-SHDDINNYLQQLDQLKGRIAELEmekqkdRELSQTLENEKN 1848
Cdd:COG3206   250 GSGPDALPELLQSPVIQQLRAQLAELEAElAELSARYTpNHPDVIALRAQIAALRAQLQQEA------QRILASLEAELE 323

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564376925 1849 ALLTQISAKDSELKLLEEEVAKINmlnqQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1916
Cdd:COG3206   324 ALQAREASLQAQLAQLEARLAELP----ELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGN 387
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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