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Conserved domains on  [gi|564367385|ref|XP_006244604|]
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kelch domain-containing protein 3 isoform X2 [Rattus norvegicus]

Protein Classification

Kelch repeat-containing protein( domain architecture ID 11459646)

Kelch repeat-containing protein, member of a superfamily of proteins with diverse functions

CATH:  2.120.10.80
Gene Ontology:  GO:0005515
PubMed:  10603472|31442578|24959344
SCOP:  3000448

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
14-308 3.16e-34

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 127.58  E-value: 3.16e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  14 RVNHAAVAVGHRVYSFGGYCSGEDYETlrqidVHIFNAVSLRWTKLPPVrpavrgqaPVVPymRYGHSTVLIDDTVFLWG 93
Cdd:COG3055   13 RSEAAAALLDGKVYVAGGLSGGSASNS-----FEVYDPATNTWSELAPL--------PGPP--RHHAAAVAQDGKLYVFG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  94 GRNDTEGACNVL---YAFDVNTHKWSTprvSGTVPGARDGHSACVLGKIMYIFGGYEQLAdcFSNDIHKLDTSTMTWTlv 170
Cdd:COG3055   78 GFTGANPSSTPLndvYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWDDGG--NVAWVEVYDPATGTWT-- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 171 cTKGNPARWRDFHSATMLGN-HMYVFGGRAdrfgpfhsnneiycnrirvFDTRTEAWLDCPHtpvLPEGRRSHSAFGYNG 249
Cdd:COG3055  151 -QLAPLPTPRDHLAAAVLPDgKILVIGGRN-------------------GSGFSNTWTTLAP---LPTARAGHAAAVLGG 207

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564367385 250 ELYIFGGYNArlnrHFHDLWKFNPGSFTWKKIepkGKGPCPRRRQCCCIVGDKIVLFGG 308
Cdd:COG3055  208 KILVFGGESG----FSDEVEAYDPATNTWTAL---GELPTPRHGHAAVLTDGKVYVIGG 259
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
14-308 3.16e-34

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 127.58  E-value: 3.16e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  14 RVNHAAVAVGHRVYSFGGYCSGEDYETlrqidVHIFNAVSLRWTKLPPVrpavrgqaPVVPymRYGHSTVLIDDTVFLWG 93
Cdd:COG3055   13 RSEAAAALLDGKVYVAGGLSGGSASNS-----FEVYDPATNTWSELAPL--------PGPP--RHHAAAVAQDGKLYVFG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  94 GRNDTEGACNVL---YAFDVNTHKWSTprvSGTVPGARDGHSACVLGKIMYIFGGYEQLAdcFSNDIHKLDTSTMTWTlv 170
Cdd:COG3055   78 GFTGANPSSTPLndvYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWDDGG--NVAWVEVYDPATGTWT-- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 171 cTKGNPARWRDFHSATMLGN-HMYVFGGRAdrfgpfhsnneiycnrirvFDTRTEAWLDCPHtpvLPEGRRSHSAFGYNG 249
Cdd:COG3055  151 -QLAPLPTPRDHLAAAVLPDgKILVIGGRN-------------------GSGFSNTWTTLAP---LPTARAGHAAAVLGG 207

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564367385 250 ELYIFGGYNArlnrHFHDLWKFNPGSFTWKKIepkGKGPCPRRRQCCCIVGDKIVLFGG 308
Cdd:COG3055  208 KILVFGGESG----FSDEVEAYDPATNTWTAL---GELPTPRHGHAAVLTDGKVYVIGG 259
PLN02153 PLN02153
epithiospecifier protein
 74-318 3.23e-16

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 78.87  E-value: 3.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  74 PYMRYGHSTVLIDDTVFLWGGRNDTEGACNV-LYAFDVNTHKWSTPRVSGTVPGARD-GHSACVLGKIMYIFGGYEQLAD 151
Cdd:PLN02153  20 PGPRCSHGIAVVGDKLYSFGGELKPNEHIDKdLYVFDFNTHTWSIAPANGDVPRISClGVRMVAVGTKLYIFGGRDEKRE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 152 cfSNDIHKLDTSTMTWTLVcTK----GNPARwRDFHSATMLGNHMYVFGGRADrfGPFHSNNEIYcNRIRVFDTRTEAWL 227
Cdd:PLN02153 100 --FSDFYSYDTVKNEWTFL-TKldeeGGPEA-RTFHSMASDENHVYVFGGVSK--GGLMKTPERF-RTIEAYNIADGKWV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 228 DCPHTPVLPEGRRSHSAFGYNGELYIFGGY------NARLNRHFHDLWKFNPGSFTWKKIEPKGKGPCPRRRQCCCIVGD 301
Cdd:PLN02153 173 QLPDPGENFEKRGGAGFAVVQGKIWVVYGFatsilpGGKSDYESNAVQFFDPASGKWTEVETTGAKPSARSVFAHAVVGK 252

                        250
                 ....*....|....*...
gi 564367385 302 KIVLFGGTS-PSPEEGLG 318
Cdd:PLN02153 253 YIIIFGGEVwPDLKGHLG 270
Kelch_2 pfam07646
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 128-171 2.73e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 462220 [Multi-domain]  Cd Length: 47  Bit Score: 43.86  E-value: 2.73e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 564367385  128 RDGHSACVLGKIMYIFGGYEQLADCFSNDIHKLDTSTMTWTLVC 171
Cdd:pfam07646   2 RYPHASSVPGGKLYVVGGSDGLGDLSSSDVLVYDPETNVWTEVP 45
 
Name Accession Description Interval E-value
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
14-308 3.16e-34

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 127.58  E-value: 3.16e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  14 RVNHAAVAVGHRVYSFGGYCSGEDYETlrqidVHIFNAVSLRWTKLPPVrpavrgqaPVVPymRYGHSTVLIDDTVFLWG 93
Cdd:COG3055   13 RSEAAAALLDGKVYVAGGLSGGSASNS-----FEVYDPATNTWSELAPL--------PGPP--RHHAAAVAQDGKLYVFG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  94 GRNDTEGACNVL---YAFDVNTHKWSTprvSGTVPGARDGHSACVLGKIMYIFGGYEQLAdcFSNDIHKLDTSTMTWTlv 170
Cdd:COG3055   78 GFTGANPSSTPLndvYVYDPATNTWTK---LAPMPTPRGGATALLLDGKIYVVGGWDDGG--NVAWVEVYDPATGTWT-- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 171 cTKGNPARWRDFHSATMLGN-HMYVFGGRAdrfgpfhsnneiycnrirvFDTRTEAWLDCPHtpvLPEGRRSHSAFGYNG 249
Cdd:COG3055  151 -QLAPLPTPRDHLAAAVLPDgKILVIGGRN-------------------GSGFSNTWTTLAP---LPTARAGHAAAVLGG 207

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564367385 250 ELYIFGGYNArlnrHFHDLWKFNPGSFTWKKIepkGKGPCPRRRQCCCIVGDKIVLFGG 308
Cdd:COG3055  208 KILVFGGESG----FSDEVEAYDPATNTWTAL---GELPTPRHGHAAVLTDGKVYVIGG 259
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
11-260 2.56e-33

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 125.27  E-value: 2.56e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  11 GPRRVNHAAVAVGHRVYSFGGYCSGEDYETLRQiDVHIFNAVSLRWTKLPPVrpavrgqapvvPYMRYGHSTVLIDDTVF 90
Cdd:COG3055   58 GPPRHHAAAVAQDGKLYVFGGFTGANPSSTPLN-DVYVYDPATNTWTKLAPM-----------PTPRGGATALLLDGKIY 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  91 LWGGRNDtEGACNVLYAFDVNTHKWSTPrvsGTVPGARDGHSACVL--GKImYIFGGYEQladcfsndihklDTSTMTWT 168
Cdd:COG3055  126 VVGGWDD-GGNVAWVEVYDPATGTWTQL---APLPTPRDHLAAAVLpdGKI-LVIGGRNG------------SGFSNTWT 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 169 lvcTKGNPARWRDFHSATMLGNHMYVFGGRadrfGPFHSNNEIYcnrirvfDTRTEAWLdcpHTPVLPEGRRSHSAFGYN 248
Cdd:COG3055  189 ---TLAPLPTARAGHAAAVLGGKILVFGGE----SGFSDEVEAY-------DPATNTWT---ALGELPTPRHGHAAVLTD 251

                        250
                 ....*....|..
gi 564367385 249 GELYIFGGYNAR 260
Cdd:COG3055  252 GKVYVIGGETKP 263
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
56-310 9.90e-25

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 102.16  E-value: 9.90e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  56 WTKLPPVrPAVRGQApvvpymryghSTVLIDDTVFLWGGrNDTEGACNVLYAFDVNTHKWSTprvSGTVPGARDGHSACV 135
Cdd:COG3055    3 WSSLPDL-PTPRSEA----------AAALLDGKVYVAGG-LSGGSASNSFEVYDPATNTWSE---LAPLPGPPRHHAAAV 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 136 L--GKImYIFGGYEQLAD--CFSNDIHKLDTSTMTWTlvcTKGNPARWRDFHSATMLGNHMYVFGGRadrfgpfhsNNEI 211
Cdd:COG3055   68 AqdGKL-YVFGGFTGANPssTPLNDVYVYDPATNTWT---KLAPMPTPRGGATALLLDGKIYVVGGW---------DDGG 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 212 YCNRIRVFDTRTEAWLDcphTPVLPEGRRSHSA-FGYNGELYIFGGYNarlnrhfhdlwkFNPGSFTWKKIEPKgkgPCP 290
Cdd:COG3055  135 NVAWVEVYDPATGTWTQ---LAPLPTPRDHLAAaVLPDGKILVIGGRN------------GSGFSNTWTTLAPL---PTA 196

                        250       260
                 ....*....|....*....|
gi 564367385 291 RRRQCCCIVGDKIVLFGGTS 310
Cdd:COG3055  197 RAGHAAAVLGGKILVFGGES 216
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
3-197 3.52e-17

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 80.97  E-value: 3.52e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385   3 RWTVHLEGGPRRVNHAAVAVGHRVYSFGGYCSGEDYEtlrqiDVHIFNAVSLRWTKLPPvrpavrgqapvVPYMRYGHS- 81
Cdd:COG3055  101 TWTKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVA-----WVEVYDPATGTWTQLAP-----------LPTPRDHLAa 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  82 TVLIDDTVFLWGGRNDTegacnvlyafdVNTHKWSTPrvsGTVPGARDGHSACVLGKIMYIFGGYEQladcFSNDIHKLD 161
Cdd:COG3055  165 AVLPDGKILVIGGRNGS-----------GFSNTWTTL---APLPTARAGHAAAVLGGKILVFGGESG----FSDEVEAYD 226

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 564367385 162 TSTMTWTLVCTKGNParwRDFHSATMLGNHMYVFGG 197
Cdd:COG3055  227 PATNTWTALGELPTP---RHGHAAVLTDGKVYVIGG 259
PLN02153 PLN02153
epithiospecifier protein
 74-318 3.23e-16

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 78.87  E-value: 3.23e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  74 PYMRYGHSTVLIDDTVFLWGGRNDTEGACNV-LYAFDVNTHKWSTPRVSGTVPGARD-GHSACVLGKIMYIFGGYEQLAD 151
Cdd:PLN02153  20 PGPRCSHGIAVVGDKLYSFGGELKPNEHIDKdLYVFDFNTHTWSIAPANGDVPRISClGVRMVAVGTKLYIFGGRDEKRE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 152 cfSNDIHKLDTSTMTWTLVcTK----GNPARwRDFHSATMLGNHMYVFGGRADrfGPFHSNNEIYcNRIRVFDTRTEAWL 227
Cdd:PLN02153 100 --FSDFYSYDTVKNEWTFL-TKldeeGGPEA-RTFHSMASDENHVYVFGGVSK--GGLMKTPERF-RTIEAYNIADGKWV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 228 DCPHTPVLPEGRRSHSAFGYNGELYIFGGY------NARLNRHFHDLWKFNPGSFTWKKIEPKGKGPCPRRRQCCCIVGD 301
Cdd:PLN02153 173 QLPDPGENFEKRGGAGFAVVQGKIWVVYGFatsilpGGKSDYESNAVQFFDPASGKWTEVETTGAKPSARSVFAHAVVGK 252

                        250
                 ....*....|....*...
gi 564367385 302 KIVLFGGTS-PSPEEGLG 318
Cdd:PLN02153 253 YIIIFGGEVwPDLKGHLG 270
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
180-322 6.97e-16

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 77.12  E-value: 6.97e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 180 RDFHSATMLGNHMYVFGGradrfgpfhSNNEIYCNRIRVFDTRTEAWLdcpHTPVLPEGRRSHSA-FGYNGELYIFGGYN 258
Cdd:COG3055   13 RSEAAAALLDGKVYVAGG---------LSGGSASNSFEVYDPATNTWS---ELAPLPGPPRHHAAaVAQDGKLYVFGGFT 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564367385 259 ARLN--RHFHDLWKFNPGSFTWKKIEPkgkGPCPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFD 322
Cdd:COG3055   81 GANPssTPLNDVYVYDPATNTWTKLAP---MPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYD 143
PLN02193 PLN02193
nitrile-specifier protein
 61-322 9.73e-16

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 78.46  E-value: 9.73e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  61 PVRPAVRGQAPVV------PYMRYGHSTVLIDDTVFLWGGR-NDTEGACNVLYAFDVNTHKWSTPRVSGTVPgardgHSA 133
Cdd:PLN02193 144 PSTPKLLGKWIKVeqkgegPGLRCSHGIAQVGNKIYSFGGEfTPNQPIDKHLYVFDLETRTWSISPATGDVP-----HLS 218

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 134 CV------LGKIMYIFGGYEqlADCFSNDIHKLDTSTMTWTLVCTKGNPARWRDFHSATMLGNHMYVFGGRADRfgpfhs 207
Cdd:PLN02193 219 CLgvrmvsIGSTLYVFGGRD--ASRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSAT------ 290

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 208 nneiycNRIRVFDTRT---EAWLDCPhTPVlpegrRSHSAFG------YNGELYIFGGYNARlnrHFHDLWKFNPGSFTW 278
Cdd:PLN02193 291 ------ARLKTLDSYNivdKKWFHCS-TPG-----DSFSIRGgaglevVQGKVWVVYGFNGC---EVDDVHYYDPVQDKW 355

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 564367385 279 KKIEPKGKGPCPRRRQCCCIVGDKIVLFGG---TSPSPEEGLGDEFD 322
Cdd:PLN02193 356 TQVETFGVRPSERSVFASAAVGKHIVIFGGeiaMDPLAHVGPGQLTD 402
PLN02153 PLN02153
epithiospecifier protein
 9-198 1.81e-13

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 70.79  E-value: 1.81e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385   9 EGGPR-RVNHAAVAVGHRVYSFGGYCSGEDYET---LRQIDVhiFNAVSLRWTKLPPvrPA-------------VRGQAP 71
Cdd:PLN02153 122 EGGPEaRTFHSMASDENHVYVFGGVSKGGLMKTperFRTIEA--YNIADGKWVQLPD--PGenfekrggagfavVQGKIW 197

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  72 VVpymrYGHSTVLIDdtvflwGGRNDTEGacNVLYAFDVNTHKWSTPRVSGTVPGARDGHSACVLGKIMYIFGGyEQLAD 151
Cdd:PLN02153 198 VV----YGFATSILP------GGKSDYES--NAVQFFDPASGKWTEVETTGAKPSARSVFAHAVVGKYIIIFGG-EVWPD 264

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564367385 152 --------CFSNDIHKLDTSTMTWTLVCTKGNPAR---WRDFHSATMLG-NHMYVFGGR 198
Cdd:PLN02153 265 lkghlgpgTLSNEGYALDTETLVWEKLGECGEPAMprgWTAYTTATVYGkNGLLMHGGK 323
PLN02193 PLN02193
nitrile-specifier protein
 167-330 6.79e-12

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 66.52  E-value: 6.79e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 167 WTLVCTKGNPARWRDFHSATMLGNHMYVFGGRadrFGPfhsnNEIYCNRIRVFDTRTEAWLDCPHTPVLPE----GRRSH 242
Cdd:PLN02193 153 WIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGE---FTP----NQPIDKHLYVFDLETRTWSISPATGDVPHlsclGVRMV 225

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 243 SAfgyNGELYIFGGYNArlNRHFHDLWKFNPGSFTWKKIEPKGKGPCPRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFD 322
Cdd:PLN02193 226 SI---GSTLYVFGGRDA--SRQYNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYN 300


                 ....*...
gi 564367385 323 LIDHSDLH 330
Cdd:PLN02193 301 IVDKKWFH 308
PLN02193 PLN02193
nitrile-specifier protein
 9-197 1.27e-11

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 65.75  E-value: 1.27e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385   9 EGGPRRVNHAAVAVGHRVYSFGGycsgeDYETLRQIDVH--IFNAVSLRWTklppVRPAVrGQAPVVPYMryGHSTVLID 86
Cdd:PLN02193 161 EGPGLRCSHGIAQVGNKIYSFGG-----EFTPNQPIDKHlyVFDLETRTWS----ISPAT-GDVPHLSCL--GVRMVSIG 228

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  87 DTVFLWGGRnDTEGACNVLYAFDVNTHKWS--TPRVSGTVPgaRDGHSACVLGKIMYIFGGYEQLA-------------- 150
Cdd:PLN02193 229 STLYVFGGR-DASRQYNGFYSFDTTTNEWKllTPVEEGPTP--RSFHSMAADEENVYVFGGVSATArlktldsynivdkk 305

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 151 ---------------------------------DCFSNDIHKLDTSTMTWTLVCTKGNPARWRDFHSATMLGNHMYVFGG 197
Cdd:PLN02193 306 wfhcstpgdsfsirggaglevvqgkvwvvygfnGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASAAVGKHIVIFGG 385
PLN02153 PLN02153
epithiospecifier protein
 122-256 3.46e-11

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 63.85  E-value: 3.46e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 122 GTVPGARDGHSACVLGKIMYIFGGYEQLADCFSNDIHKLDTSTMTWTLVCTKGNPARWRDFH-SATMLGNHMYVFGGRAD 200
Cdd:PLN02153  17 GKGPGPRCSHGIAVVGDKLYSFGGELKPNEHIDKDLYVFDFNTHTWSIAPANGDVPRISCLGvRMVAVGTKLYIFGGRDE 96

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 201 R--FGPFHSnneiycnrirvFDTRTEAWLDCPHTPVL--PEGRRSHSAFGYNGELYIFGG 256
Cdd:PLN02153  97 KreFSDFYS-----------YDTVKNEWTFLTKLDEEggPEARTFHSMASDENHVYVFGG 145
PHA03098 PHA03098
kelch-like protein; Provisional
 77-308 8.03e-11

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 63.25  E-value: 8.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  77 RYGHSTVLIDDTVFLWGGRNDTEGACNVLYAFDVNTHKWstprvsGTVP---GARDGHSACVLGKIMYIFGGYEQlaDCF 153
Cdd:PHA03098 285 VYCFGSVVLNNVIYFIGGMNKNNLSVNSVVSYDTKTKSW------NKVPeliYPRKNPGVTVFNNRIYVIGGIYN--SIS 356

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 154 SNDIHKLDTSTMTWTLVCTKGNParwRDFHSATMLGNHMYVFGGRadrfgpfhSNNEIYCNRIRVFDTRTEAWLDCPHTP 233
Cdd:PHA03098 357 LNTVESWKPGESKWREEPPLIFP---RYNPCVVNVNNLIYVIGGI--------SKNDELLKTVECFSLNTNKWSKGSPLP 425

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564367385 234 VLPEGrrsHSAFGYNGELYIFGGYNARLNRH-FHDLWKFNPGSFTWKKIEPKGKgpcPRRRQCCCIVGDKIVLFGG 308
Cdd:PHA03098 426 ISHYG---GCAIYHDGKIYVIGGISYIDNIKvYNIVESYNPVTNKWTELSSLNF---PRINASLCIFNNKIYVVGG 495
PHA03098 PHA03098
kelch-like protein; Provisional
 14-235 2.44e-09

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 58.63  E-value: 2.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  14 RVNHAAVAVGHRVYSFGGYCSGEDYetlrqIDVHIFNAVSLRWTKLPPVRpavrgqapvvpYMRYGHSTVLIDDTVFLWG 93
Cdd:PHA03098 333 RKNPGVTVFNNRIYVIGGIYNSISL-----NTVESWKPGESKWREEPPLI-----------FPRYNPCVVNVNNLIYVIG 396

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  94 GRNDTEGACNVLYAFDVNTHKWSTPRVSgtvPGARDGHSACVLGKIMYIFGG--YEQLADCFSNdIHKLDTSTMTWT--- 168
Cdd:PHA03098 397 GISKNDELLKTVECFSLNTNKWSKGSPL---PISHYGGCAIYHDGKIYVIGGisYIDNIKVYNI-VESYNPVTNKWTels 472

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564367385 169 -LVCTKGNParwrdfhSATMLGNHMYVFGGradrfgpfhSNNEIYCNRIRVFDTRTEAW-LDCPHTPVL 235
Cdd:PHA03098 473 sLNFPRINA-------SLCIFNNKIYVVGG---------DKYEYYINEIEVYDDKTNTWtLFCKFPKVI 525
Kelch_2 pfam07646
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 128-171 2.73e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 462220 [Multi-domain]  Cd Length: 47  Bit Score: 43.86  E-value: 2.73e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 564367385  128 RDGHSACVLGKIMYIFGGYEQLADCFSNDIHKLDTSTMTWTLVC 171
Cdd:pfam07646   2 RYPHASSVPGGKLYVVGGSDGLGDLSSSDVLVYDPETNVWTEVP 45
Kelch_3 pfam13415
Galactose oxidase, central domain;
86-136 5.02e-06

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 43.05  E-value: 5.02e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 564367385   86 DDTVFLWGGRNDTEGAC-NVLYAFDVNTHKWSTPrvsGTVPGARDGHSACVL 136
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRlNDLYVYDLDTNTWTQI---GDLPPPRSGHSATYI 49
PLN02772 PLN02772
guanylate kinase
 81-145 9.42e-06

guanylate kinase


Pssm-ID: 215414 [Multi-domain]  Cd Length: 398  Bit Score: 47.14  E-value: 9.42e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564367385  81 STVLIDDTVFLWGGRNDTEGACNVLYAFDVNTHKWSTPRVSGTVPGARDGHSACVL--GKIMYIFGG 145
Cdd:PLN02772  29 TSVTIGDKTYVIGGNHEGNTLSIGVQILDKITNNWVSPIVLGTGPKPCKGYSAVVLnkDRILVIKKG 95
Kelch_4 pfam13418
Galactose oxidase, central domain;
77-117 1.56e-05

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 41.83  E-value: 1.56e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 564367385   77 RYGHSTVLI-DDTVFLWGGRNDTEGACNVLYAFDVNTHKWST 117
Cdd:pfam13418   2 RAYHTSTSIpDDTIYLFGGEGEDGTLLSDLWVFDLSTNEWTR 43
PLN02193 PLN02193
nitrile-specifier protein
 8-203 2.20e-05

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 46.10  E-value: 2.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385   8 LEGGPR-RVNHAAVAVGHRVYSFGGYCSGEDYETLRQidvhiFNAVSLRW--TKLPPVRPAVRGQA--PVVP---YMRYG 79
Cdd:PLN02193 262 VEEGPTpRSFHSMAADEENVYVFGGVSATARLKTLDS-----YNIVDKKWfhCSTPGDSFSIRGGAglEVVQgkvWVVYG 336

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  80 HSTVLIDDtvflwggrndtegacnvLYAFDVNTHKWSTPRVSGTVPGARDGHSACVLGKIMYIFGG---YEQLADC---- 152
Cdd:PLN02193 337 FNGCEVDD-----------------VHYYDPVQDKWTQVETFGVRPSERSVFASAAVGKHIVIFGGeiaMDPLAHVgpgq 399

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564367385 153 FSNDIHKLDTSTMTW----TLVCTKGNPAR--WRDFHSATMLGNH-MYVFGGRA---DRFG 203
Cdd:PLN02193 400 LTDGTFALDTETLQWerldKFGEEEETPSSrgWTASTTGTIDGKKgLVMHGGKAptnDRFD 460
Kelch_6 pfam13964
Kelch motif;
14-61 2.40e-05

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 41.17  E-value: 2.40e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 564367385   14 RVNHAAVAVGHRVYSFGGYCSGEDYetlrQIDVHIFNAVSLRWTKLPP 61
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTNASPA----LNKLEVYNPLTKSWEELPP 45
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 236-276 2.41e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 41.01  E-value: 2.41e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 564367385  236 PEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPGSF 276
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQPSDDVYVLSLPTF 41
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 125-164 2.63e-05

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 41.01  E-value: 2.63e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 564367385  125 PGARDGHSACVLGKIMYIFGGYEQLADCFSNDIHKLDTST 164
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQPSDDVYVLSLPT 40
PRK14131 PRK14131
N-acetylneuraminate epimerase;
155-268 5.23e-05

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 45.01  E-value: 5.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385 155 NDIHKLDTSTMT--WTLVCTKGNPARwrDFHSATMLGNHMYVFGG--RADRFGPFHSNNEIYcnrirVFDTRTEAWLDCP 230
Cdd:PRK14131  50 TSWYKLDLNAPSkgWTKIAAFPGGPR--EQAVAAFIDGKLYVFGGigKTNSEGSPQVFDDVY-----KYDPKTNSWQKLD 122

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 564367385 231 -HTPVlpeGRRSHSAFGYNG-ELYIFGGYNARL-NRHFHDL 268
Cdd:PRK14131 123 tRSPV---GLAGHVAVSLHNgKAYITGGVNKNIfDGYFEDL 160
Kelch_4 pfam13418
Galactose oxidase, central domain;
13-62 6.06e-05

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 40.29  E-value: 6.06e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 564367385   13 RRVNHAAVAVG-HRVYSFGGYcsGEDYETLrqIDVHIFNAVSLRWTKLPPV 62
Cdd:pfam13418   1 PRAYHTSTSIPdDTIYLFGGE--GEDGTLL--SDLWVFDLSTNEWTRLGSL 47
Kelch_3 pfam13415
Galactose oxidase, central domain;
248-299 1.24e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 39.20  E-value: 1.24e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 564367385  248 NGELYIFGGYNARLNRHFHDLWKFNPGSFTWKKIepkgkGPCPRRRQCCCIV 299
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRLNDLYVYDLDTNTWTQI-----GDLPPPRSGHSAT 47
Kelch_6 pfam13964
Kelch motif;
76-117 1.60e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 38.86  E-value: 1.60e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 564367385   76 MRYGHSTVLIDDTVFLWGGRNDTEGACNVLYAFDVNTHKWST 117
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEE 42
Kelch_6 pfam13964
Kelch motif;
239-283 2.35e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 38.47  E-value: 2.35e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 564367385  239 RRSHSAFGYNGELYIFGGYNARLNRHFhDLWKFNPGSFTWKKIEP 283
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGYTNASPALN-KLEVYNPLTKSWEELPP 45
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 239-283 3.74e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 37.98  E-value: 3.74e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 564367385  239 RRSHSAFGYNGELYIFGGYNArlNRHFHDLWKFNPGSFTWKKIEP 283
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFDG--NQSLNSVEVYDPETNTWSKLPS 44
Kelch_3 pfam13415
Galactose oxidase, central domain;
137-186 4.31e-04

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 37.65  E-value: 4.31e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 564367385  137 GKIMYIFGGYEQLADCFSNDIHKLDTSTMTWTlVCTKGNPArwRDFHSAT 186
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRLNDLYVYDLDTNTWT-QIGDLPPP--RSGHSAT 47
Kelch_4 pfam13418
Galactose oxidase, central domain;
238-284 4.51e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 37.59  E-value: 4.51e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 564367385  238 GRRSHSAFG-YNGELYIFGGYNA---RLNrhfhDLWKFNPGSFTWKKIEPK 284
Cdd:pfam13418   1 PRAYHTSTSiPDDTIYLFGGEGEdgtLLS----DLWVFDLSTNEWTRLGSL 47
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 13-61 6.36e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 37.21  E-value: 6.36e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 564367385   13 RRVNHAAVAVGHRVYSFGGYCSGEdyetlRQIDVHIFNAVSLRWTKLPP 61
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQ-----SLNSVEVYDPETNTWSKLPS 44
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 127-170 6.95e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 37.21  E-value: 6.95e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 564367385  127 ARDGHSACVLGKIMYIFGGYEqlADCFSNDIHKLDTSTMTWTLV 170
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFD--GNQSLNSVEVYDPETNTWSKL 42
Kelch_2 pfam07646
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 13-62 7.42e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 462220 [Multi-domain]  Cd Length: 47  Bit Score: 36.93  E-value: 7.42e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 564367385   13 RRVNHAAVAVGHRVYSFGGYCSGEDyetLRQIDVHIFNAVSLRWTKLPPV 62
Cdd:pfam07646   1 PRYPHASSVPGGKLYVVGGSDGLGD---LSSSDVLVYDPETNVWTEVPRL 47
Kelch_6 pfam13964
Kelch motif;
179-230 9.05e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 36.93  E-value: 9.05e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 564367385  179 WRDFHSATMLGNHMYVFGGRADRFGPFhsnneiycNRIRVFDTRTEAWLDCP 230
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYTNASPAL--------NKLEVYNPLTKSWEELP 44
PRK14131 PRK14131
N-acetylneuraminate epimerase;
10-96 1.31e-03

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 40.38  E-value: 1.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  10 GGPRrvNHA-AVAVGHRVYSFGGycSG-EDYETLRQI--DVHIFNAVSLRWTKLPPVRPavRGQApvvpymryGHSTVLI 85
Cdd:PRK14131  72 GGPR--EQAvAAFIDGKLYVFGG--IGkTNSEGSPQVfdDVYKYDPKTNSWQKLDTRSP--VGLA--------GHVAVSL 137

                         90
                 ....*....|..
gi 564367385  86 DDT-VFLWGGRN 96
Cdd:PRK14131 138 HNGkAYITGGVN 149
PRK14131 PRK14131
N-acetylneuraminate epimerase;
65-197 3.52e-03

N-acetylneuraminate epimerase;


Pssm-ID: 237617 [Multi-domain]  Cd Length: 376  Bit Score: 39.23  E-value: 3.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564367385  65 AVRGQAPVVPY-MRYGHSTvLIDDTVFLWGGrndteGACNVLYAFDVNT--HKWStpRVSGTVPGARDGHSACVLGKIMY 141
Cdd:PRK14131  17 ANAEQLPDLPVpFKNGTGA-IDNNTVYVGLG-----SAGTSWYKLDLNApsKGWT--KIAAFPGGPREQAVAAFIDGKLY 88

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564367385 142 IFGGYEQLADCFS----NDIHKLDTSTMTWTLVCTKgnPARWRDFHSATML-GNHMYVFGG 197
Cdd:PRK14131  89 VFGGIGKTNSEGSpqvfDDVYKYDPKTNSWQKLDTR--SPVGLAGHVAVSLhNGKAYITGG 147
Kelch_4 pfam13418
Galactose oxidase, central domain;
127-170 4.02e-03

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 34.90  E-value: 4.02e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 564367385  127 ARDGHSACVLGK-IMYIFGGYeQLADCFSNDIHKLDTSTMTWTLV 170
Cdd:pfam13418   1 PRAYHTSTSIPDdTIYLFGGE-GEDGTLLSDLWVFDLSTNEWTRL 44
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 180-230 4.94e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 34.51  E-value: 4.94e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 564367385  180 RDFHSATMLGNHMYVFGGRadrfgpfhsNNEIYCNRIRVFDTRTEAWLDCP 230
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGF---------DGNQSLNSVEVYDPETNTWSKLP 43
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 76-116 5.73e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 34.51  E-value: 5.73e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 564367385   76 MRYGHSTVLIDDTVFLWGGRNDTEgACNVLYAFDVNTHKWS 116
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDGNQ-SLNSVEVYDPETNTWS 40
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 74-112 6.07e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 34.46  E-value: 6.07e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 564367385   74 PYMRYGHSTVLIDDTVFLWGGRNDTEGA-CNVLYAFDVNT 112
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQpSDDVYVLSLPT 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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