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Conserved domains on  [gi|564364067|ref|XP_006243268|]
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uveal autoantigen with coiled-coil domains and ankyrin repeats isoform X2 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
19-242 1.75e-40

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 151.65  E-value: 1.75e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   19 NKYDDRLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKY 98
Cdd:COG0666    51 DALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYN 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   99 GHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGA 178
Cdd:COG0666   131 GNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGA 210

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564364067  179 DVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLTLLDALGHDSSYYARIGDNLDILNLLKTA 242
Cdd:COG0666   211 DVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLA 274
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 441-1234 1.40e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.51  E-value: 1.40e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   441 DSAKQDRLKLQNELAHKVAECKALALECERVKEDSDE---QIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNe 517
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN- 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   518 aatgSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVT 597
Cdd:TIGR02168  314 ----LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   598 ELEGQLKELGAKLALSVPT-ETFESMKSSLSNDISEKAKRLAEVgrDYESSQGEIRQLKRDLESVRAQHIRPEEH-EQLR 675
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARlERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEAlEELR 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   676 SRLEQKSGELGKKVTELTLKN------QTLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKAhdvnvedLN 749
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQarldslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAA-------IE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   750 KKLSDATQRYAEKKLEAERLLAENDKltKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALM 829
Cdd:TIGR02168  541 AALGGRLQAVVVENLNAAKKAIAFLK--QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAL 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   830 SentslkkTLSSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVL--RRNLENVQNQMKADYV 907
Cdd:TIGR02168  619 S-------YLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerRREIEELEEKIEELEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   908 SLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEK 987
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   988 ALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKT-------EELGKQLKELS 1060
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIaaterrlEDLEEQIEELS 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1061 QKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLL 1140
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1141 EnqksssVTLADHLQLKEALEKEVGIMkasLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATK--- 1217
Cdd:TIGR02168  932 E------GLEVRIDNLQERLSEEYSLT---LEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKery 1002

                          810
                   ....*....|....*..
gi 564364067  1218 NDLETQISNLNDKLASL 1234
Cdd:TIGR02168 1003 DFLTAQKEDLTEAKETL 1019
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1117-1373 6.60e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 6.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1117 EELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLqlkEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTK 1196
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL---AALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1197 QALKNLETREVVDMSKYkatkndletQISNLNDKLASLnrkydqvceekVSAKDEKELLHL--NIEQEIRDQKERCDKSL 1274
Cdd:COG4942    97 AELEAQKEELAELLRAL---------YRLGRQPPLALL-----------LSPEDFLDAVRRlqYLKYLAPARREQAEELR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1275 TTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQSQLVDTLQQRVRDLQQQLADADRQH 1354
Cdd:COG4942   157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236

                         250
                  ....*....|....*....
gi 564364067 1355 QEVIAIYRTHLLSAAQGHM 1373
Cdd:COG4942   237 AAAAERTPAAGFAALKGKL 255
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
19-242 1.75e-40

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 151.65  E-value: 1.75e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   19 NKYDDRLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKY 98
Cdd:COG0666    51 DALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYN 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   99 GHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGA 178
Cdd:COG0666   131 GNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGA 210

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564364067  179 DVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLTLLDALGHDSSYYARIGDNLDILNLLKTA 242
Cdd:COG0666   211 DVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLA 274
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 441-1234 1.40e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.51  E-value: 1.40e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   441 DSAKQDRLKLQNELAHKVAECKALALECERVKEDSDE---QIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNe 517
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN- 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   518 aatgSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVT 597
Cdd:TIGR02168  314 ----LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   598 ELEGQLKELGAKLALSVPT-ETFESMKSSLSNDISEKAKRLAEVgrDYESSQGEIRQLKRDLESVRAQHIRPEEH-EQLR 675
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARlERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEAlEELR 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   676 SRLEQKSGELGKKVTELTLKN------QTLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKAhdvnvedLN 749
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQarldslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAA-------IE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   750 KKLSDATQRYAEKKLEAERLLAENDKltKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALM 829
Cdd:TIGR02168  541 AALGGRLQAVVVENLNAAKKAIAFLK--QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAL 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   830 SentslkkTLSSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVL--RRNLENVQNQMKADYV 907
Cdd:TIGR02168  619 S-------YLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerRREIEELEEKIEELEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   908 SLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEK 987
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   988 ALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKT-------EELGKQLKELS 1060
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIaaterrlEDLEEQIEELS 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1061 QKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLL 1140
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1141 EnqksssVTLADHLQLKEALEKEVGIMkasLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATK--- 1217
Cdd:TIGR02168  932 E------GLEVRIDNLQERLSEEYSLT---LEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKery 1002

                          810
                   ....*....|....*..
gi 564364067  1218 NDLETQISNLNDKLASL 1234
Cdd:TIGR02168 1003 DFLTAQKEDLTEAKETL 1019
PTZ00121 PTZ00121
MAEBL; Provisional
 441-1263 1.91e-19

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 95.59  E-value: 1.91e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  441 DSAKQDRLKLQNELAHKVAEcKALALECERVKEDS--DEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNEA 518
Cdd:PTZ00121 1082 DAKEDNRADEATEEAFGKAE-EAKKTETGKAEEARkaEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKA 1160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  519 ATGshRVIEELReQLKDMKGKYEGASAEVGKLRNQIKQSE---MLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRR 595
Cdd:PTZ00121 1161 EDA--RKAEEAR-KAEDAKKAEAARKAEEVRKAEELRKAEdarKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKK 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  596 VTELEGQLKELGAKLALSVPTETFESMKSSLSNDISEKAKRLAEVGRDYEssqgeirQLKRDLESVRAQHIRPEEHEQLR 675
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAE-------EKKKADEAKKAEEKKKADEAKKK 1310

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  676 SRLEQKSGELGKKVTELTLKNQTLQKEVEKLyadnkllNQQVHSLTVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKlSDA 755
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEA-------KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK-ADA 1382

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  756 TQRYAEKKLEAERLLAENDKLTKNVSRLEAVFVAPEKHEKelmgLKSNiAELKMQLCELNKKcGEGQEKIRALMSENTSL 835
Cdd:PTZ00121 1383 AKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADE----AKKK-AEEKKKADEAKKK-AEEAKKADEAKKKAEEA 1456

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  836 KKtlsSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRR--NLENVQNQMKADYVSLEEHS 913
Cdd:PTZ00121 1457 KK---AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKadEAKKAEEAKKADEAKKAEEA 1533

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  914 RKMNMANQSlKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQL 993
Cdd:PTZ00121 1534 KKADEAKKA-EEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA 1612

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  994 sEQTHKGQVRDEEVKKGKQEnerlRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSERE-- 1071
Cdd:PTZ00121 1613 -KKAEEAKIKAEELKKAEEE----KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEde 1687

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1072 -KLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTS---LNGTIEHLK---EELRSKERCLEREQQAVSQLQQLL--EN 1142
Cdd:PTZ00121 1688 kKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAeeeNKIKAEEAKkeaEEDKKKAEEAKKDEEEKKKIAHLKkeEE 1767

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1143 QKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTK---EVSKLQTEVQNTKQALKNLETREVVDMS-------- 1211
Cdd:PTZ00121 1768 KKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFAniiEGGKEGNLVINDSKEMEDSAIKEVADSKnmqleead 1847

                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 564364067 1212 ---KYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKELLHLNIEQEI 1263
Cdd:PTZ00121 1848 afeKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREI 1902
Ank_2 pfam12796
Ankyrin repeats (3 copies);
92-184 5.91e-19

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 82.86  E-value: 5.91e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067    92 LHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHgASVNAKDiDGRTPLVLATQMCRPTICQ 171
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 564364067   172 LLIDRGADVNSRD 184
Cdd:pfam12796   79 LLLEKGADINVKD 91
PHA03095 PHA03095
ankyrin-like protein; Provisional
 35-203 6.82e-18

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 88.54  E-value: 6.82e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   35 EKVSSILAKKGVHPGKLDVEGRSAFHV--VAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGH--ALCLQKLLQY 110
Cdd:PHA03095  132 PKVIRLLLRKGADVNALDLYGMTPLAVllKSRNANVELLRLLIDAGADVYAVDDRFRSLLHHHLQSFKprARIVRELIRA 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  111 NCPTEHVDLQGRTALHDAAM-ADCPSS-IQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNR 188
Cdd:PHA03095  212 GCDPAATDMLGNTPLHSMATgSSCKRSlVLPLLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGN 291

                         170
                  ....*....|....*
gi 564364067  189 TALMLGCEYGCRDAV 203
Cdd:PHA03095  292 TPLSLMVRNNNGRAV 306
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 429-1195 2.06e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 75.54  E-value: 2.06e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   429 LKKELEAMRTFCDSAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLedalkdvQKRMYESEGKVKQMQTHFL 508
Cdd:pfam15921  122 MQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQL-------RKMMLSHEGVLQEIRSILV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   509 ALKEHLTNEAATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEenKRLQKEcstceid 588
Cdd:pfam15921  195 DFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIE--LLLQQH------- 265

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   589 RERRGRRVTELEGQLKELgaklalsvpTETFESMKSSlSNDISEKAKRLAEVGRDYESSQgeIRQLKrDLESVRAQhIRP 668
Cdd:pfam15921  266 QDRIEQLISEHEVEITGL---------TEKASSARSQ-ANSIQSQLEIIQEQARNQNSMY--MRQLS-DLESTVSQ-LRS 331

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   669 EEHEQLRSrLEQKSGELGKkvtELTLKNQTL---QKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMkkahdvnv 745
Cdd:pfam15921  332 ELREAKRM-YEDKIEELEK---QLVLANSELteaRTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQ-------- 399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   746 edlNKKLSDatqRYAEKKLEAERLLAENDKLTKNVSRLEAVFVAPE-----KHEKELMGLKSNIAELKmQLCELNKKCGE 820
Cdd:pfam15921  400 ---NKRLWD---RDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKsecqgQMERQMAAIQGKNESLE-KVSSLTAQLES 472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   821 GQEKIRALMSENTSLKKTLSSQyvpAKTHEEVKASLSS---TLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRrnleN 897
Cdd:pfam15921  473 TKEMLRKVVEELTAKKMTLESS---ERTVSDLTASLQEkerAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLR----N 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   898 VQNQMKADYVSLEEHSRKMNMANQSLKE-----AQDAHTALLADYRQGQeeivtLHAEIKAQKKELdtiQECIKLKYAPL 972
Cdd:pfam15921  546 VQTECEALKLQMAEKDKVIEILRQQIENmtqlvGQHGRTAGAMQVEKAQ-----LEKEINDRRLEL---QEFKILKDKKD 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   973 SRMEECERKFkateKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELkdrNVLVEEAREAERALSRKTEEL 1052
Cdd:pfam15921  618 AKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNEL---NSLSEDYEVLKRNFRNKSEEM 690

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1053 GKQLKELSQKYSDVKSE----REKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSlngtIEHLKEELR--SKERCL 1126
Cdd:pfam15921  691 ETTTNKLKMQLKSAQSEleqtRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK----IQFLEEAMTnaNKEKHF 766

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564364067  1127 EREQQavSQLQQLLENQKSSSVTLADHLQLKEALEK---------EVGIMKASLREKEEESQKKTKEVSKLQTEVQNT 1195
Cdd:pfam15921  767 LKEEK--NKLSQELSTVATEKNKMAGELEVLRSQERrlkekvanmEVALDKASLQFAECQDIIQRQEQESVRLKLQHT 842
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1026-1391 6.81e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 6.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1026 KELKDRnvlvEEAREAERALSRKtEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQpvpLEQVEALK 1105
Cdd:COG1196   216 RELKEE----LKELEAELLLLKL-RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL---ELELEEAQ 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1106 TSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEV 1185
Cdd:COG1196   288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1186 SKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDQVcEEKVSAKDEKELLHLNIEQEIRD 1265
Cdd:COG1196   368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL-EELEEALAELEEEEEEEEEALEE 446

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1266 QKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTyssggpTKRQSQLVDTLQQRVRDLQQ 1345
Cdd:COG1196   447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE------ADYEGFLEGVKAALLLAGLR 520

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 564364067 1346 QLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGL 1391
Cdd:COG1196   521 GLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566
trp TIGR00870
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...
 9-221 4.72e-08

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273311 [Multi-domain]  Cd Length: 743  Bit Score: 57.78  E-value: 4.72e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067     9 ASNHSLSAEWNKYddrlMKAAERGDVEKVSsilaKKGVHPGKLDVE-----GRSAFHVVAAKGNLECLNAIL-THGIDVA 82
Cdd:TIGR00870    9 AEESPLSDEEKAF----LPAAERGDLASVY----RDLEEPKKLNINcpdrlGRSALFVAAIENENLELTELLlNLSCRGA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067    83 TrdsaGRNALHLAAKYGHA---LCLQKLLQ---YNCPTEHVDLQ-------GRTALHDAAMADCPSSIQLLCDHGASVNA 149
Cdd:TIGR00870   81 V----GDTLLHAISLEYVDaveAILLHLLAafrKSGPLELANDQytseftpGITALHLAAHRQNYEIVKLLLERGASVPA 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   150 K----------DID----GRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALML-------GCEY----------- 197
Cdd:TIGR00870  157 RacgdffvksqGVDsfyhGESPLNAAACLGSPSIVALLSEDPADILTADSLGNTLLHLlvmenefKAEYeelscqmynfa 236

                          250       260       270
                   ....*....|....*....|....*....|
gi 564364067   198 -----GCRDAVEV-LVRNGADLTLLDALGH 221
Cdd:TIGR00870  237 lslldKLRDSKELeVILNHQGLTPLKLAAK 266
TRPV5-6 cd22192
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...
 63-191 1.19e-06

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.


Pssm-ID: 411976 [Multi-domain]  Cd Length: 609  Bit Score: 53.09  E-value: 1.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   63 AAKGNLECLNAILT-HGIDVATRDSAGRNALHLAAKYGHALCLQKLLqyNCPTEHVDL-------QGRTALHDAAMADCP 134
Cdd:cd22192    25 AKENDVQAIKKLLKcPSCDLFQRGALGETALHVAALYDNLEAAVVLM--EAAPELVNEpmtsdlyQGETALHIAVVNQNL 102

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564364067  135 SSIQLLCDHGASVNA---------KDID-----GRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTAL 191
Cdd:cd22192   103 NLVRELIARGADVVSpratgtffrPGPKnliyyGEHPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVL 173
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1117-1373 6.60e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 6.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1117 EELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLqlkEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTK 1196
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL---AALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1197 QALKNLETREVVDMSKYkatkndletQISNLNDKLASLnrkydqvceekVSAKDEKELLHL--NIEQEIRDQKERCDKSL 1274
Cdd:COG4942    97 AELEAQKEELAELLRAL---------YRLGRQPPLALL-----------LSPEDFLDAVRRlqYLKYLAPARREQAEELR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1275 TTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQSQLVDTLQQRVRDLQQQLADADRQH 1354
Cdd:COG4942   157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236

                         250
                  ....*....|....*....
gi 564364067 1355 QEVIAIYRTHLLSAAQGHM 1373
Cdd:COG4942   237 AAAAERTPAAGFAALKGKL 255
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
19-242 1.75e-40

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 151.65  E-value: 1.75e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   19 NKYDDRLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKY 98
Cdd:COG0666    51 DALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYN 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   99 GHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGA 178
Cdd:COG0666   131 GNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGA 210

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564364067  179 DVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLTLLDALGHDSSYYARIGDNLDILNLLKTA 242
Cdd:COG0666   211 DVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLA 274
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
16-242 1.04e-38

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 146.64  E-value: 1.04e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   16 AEWNKYDDRLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLA 95
Cdd:COG0666    15 LLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDDGGNTLLHAA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   96 AKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLID 175
Cdd:COG0666    95 ARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLE 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564364067  176 RGADVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLTLLDALGHDSSYYARIGDNLDILNLLKTA 242
Cdd:COG0666   175 AGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEA 241
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
25-222 3.65e-32

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 127.76  E-value: 3.65e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   25 LMKAAERGDVEKVSsILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCL 104
Cdd:COG0666    91 LHAAARNGDLEIVK-LLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGNLEIV 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  105 QKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRD 184
Cdd:COG0666   170 KLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKD 249

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 564364067  185 KQNRTALMLGCEYGCRDAVEVLVRNGADLTLLDALGHD 222
Cdd:COG0666   250 KDGLTALLLAAAAGAALIVKLLLLALLLLAAALLDLLT 287
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
40-239 6.49e-30

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 121.21  E-value: 6.49e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   40 ILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDL 119
Cdd:COG0666     6 LLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAKDD 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  120 QGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGC 199
Cdd:COG0666    86 GGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAANGN 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 564364067  200 RDAVEVLVRNGADLTLLDALGHDSSYYARIGDNLDILNLL 239
Cdd:COG0666   166 LEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIVKLL 205
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
25-191 2.56e-22

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 98.87  E-value: 2.56e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   25 LMKAAERGDVEKVSsILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCL 104
Cdd:COG0666   124 LHLAAYNGNLEIVK-LLLEAGADVNAQDNDGNTPLHLAAANGNLEIVKLLLEAGADVNARDNDGETPLHLAAENGHLEIV 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  105 QKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRD 184
Cdd:COG0666   203 KLLLEAGADVNAKDNDGKTALDLAAENGNLEIVKLLLEAGADLNAKDKDGLTALLLAAAAGAALIVKLLLLALLLLAAAL 282


                  ....*..
gi 564364067  185 KQNRTAL 191
Cdd:COG0666   283 LDLLTLL 289
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 441-1234 1.40e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.51  E-value: 1.40e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   441 DSAKQDRLKLQNELAHKVAECKALALECERVKEDSDE---QIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNe 517
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAN- 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   518 aatgSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVT 597
Cdd:TIGR02168  314 ----LERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVA 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   598 ELEGQLKELGAKLALSVPT-ETFESMKSSLSNDISEKAKRLAEVgrDYESSQGEIRQLKRDLESVRAQHIRPEEH-EQLR 675
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARlERLEDRRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEAlEELR 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   676 SRLEQKSGELGKKVTELTLKN------QTLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKAhdvnvedLN 749
Cdd:TIGR02168  468 EELEEAEQALDAAERELAQLQarldslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAA-------IE 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   750 KKLSDATQRYAEKKLEAERLLAENDKltKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALM 829
Cdd:TIGR02168  541 AALGGRLQAVVVENLNAAKKAIAFLK--QNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAL 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   830 SentslkkTLSSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVL--RRNLENVQNQMKADYV 907
Cdd:TIGR02168  619 S-------YLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILerRREIEELEEKIEELEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   908 SLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEK 987
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLE 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   988 ALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKT-------EELGKQLKELS 1060
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIaaterrlEDLEEQIEELS 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1061 QKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLL 1140
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1141 EnqksssVTLADHLQLKEALEKEVGIMkasLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATK--- 1217
Cdd:TIGR02168  932 E------GLEVRIDNLQERLSEEYSLT---LEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKery 1002

                          810
                   ....*....|....*..
gi 564364067  1218 NDLETQISNLNDKLASL 1234
Cdd:TIGR02168 1003 DFLTAQKEDLTEAKETL 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 467-1315 1.71e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.51  E-value: 1.71e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   467 ECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQtHFLALKEHLTNEAATGSHRVIEELREQLKDMKGKYEGASAE 546
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKSLERQAEKAE-RYKELKAELRELELALLVLRLEELREELEELQEELKEAEEE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   547 VGKLRNQIKQSEMLVEGFK----RDESRLVEENKRLQ---KECSTCEIDRERRGRRVTELEGQLKELGAKLalsvptETF 619
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRlevsELEEEIEELQKELYalaNEISRLEQQKQILRERLANLERQLEELEAQL------EEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   620 ESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDL-ESVRAQHIRPEEHEQLRSR---LEQKSGELGKKVTELTLK 695
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELeELESRLEELEEQLETLRSKvaqLELQIASLNNEIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   696 NQTLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKAHDvnVEDLNKKLSDATQRYAEKKleaERLLAENDK 775
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEE--LERLEEALEELREELEEAE---QALDAAERE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   776 LTKNVSRLEAVfvapEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSS--QYVPAKTHEEVK 853
Cdd:TIGR02168  484 LAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGrlQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   854 ASLS----STLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVsleehsrkMNMANQSLKEAQDA 929
Cdd:TIGR02168  560 KAIAflkqNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA--------LSYLLGGVLVVDDL 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   930 HTAL-LADYRQGQEEIVTL------------------HAEIKAQKKELDTIQECIklkyaplsrmEECERKFKATEKALK 990
Cdd:TIGR02168  632 DNALeLAKKLRPGYRIVTLdgdlvrpggvitggsaktNSSILERRREIEELEEKI----------EELEEKIAELEKALA 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   991 EQLSEQthkgQVRDEEVKKGKQENERLRKDLAALQKELkdrnvlvEEAREAERALSRKTEELGKQLKELSQKYSDVKSER 1070
Cdd:TIGR02168  702 ELRKEL----EELEEELEQLRKELEELSRQISALRKDL-------ARLEAEVEQLEERIAQLSKELTELEAEIEELEERL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1071 EKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTL 1150
Cdd:TIGR02168  771 EEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1151 ADHLqlkEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETrevvDMSKYKATKNDLETQISNLNDK 1230
Cdd:TIGR02168  851 SEDI---ESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSE----ELRELESKRSELRRELEELREK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1231 LASLNRKYDQvceekvsakdekellhlnIEQEIRDQKERcdkslttIMELQQRIQESAKQIEAK-DNKITELLNDVERLK 1309
Cdd:TIGR02168  924 LAQLELRLEG------------------LEVRIDNLQER-------LSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978


                   ....*.
gi 564364067  1310 QALNGL 1315
Cdd:TIGR02168  979 NKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 441-1263 1.91e-19

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 95.59  E-value: 1.91e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  441 DSAKQDRLKLQNELAHKVAEcKALALECERVKEDS--DEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNEA 518
Cdd:PTZ00121 1082 DAKEDNRADEATEEAFGKAE-EAKKTETGKAEEARkaEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKA 1160

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  519 ATGshRVIEELReQLKDMKGKYEGASAEVGKLRNQIKQSE---MLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRR 595
Cdd:PTZ00121 1161 EDA--RKAEEAR-KAEDAKKAEAARKAEEVRKAEELRKAEdarKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKK 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  596 VTELEGQLKELGAKLALSVPTETFESMKSSLSNDISEKAKRLAEVGRDYEssqgeirQLKRDLESVRAQHIRPEEHEQLR 675
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAE-------EKKKADEAKKAEEKKKADEAKKK 1310

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  676 SRLEQKSGELGKKVTELTLKNQTLQKEVEKLyadnkllNQQVHSLTVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKlSDA 755
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEA-------KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKK-ADA 1382

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  756 TQRYAEKKLEAERLLAENDKLTKNVSRLEAVFVAPEKHEKelmgLKSNiAELKMQLCELNKKcGEGQEKIRALMSENTSL 835
Cdd:PTZ00121 1383 AKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADE----AKKK-AEEKKKADEAKKK-AEEAKKADEAKKKAEEA 1456

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  836 KKtlsSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRR--NLENVQNQMKADYVSLEEHS 913
Cdd:PTZ00121 1457 KK---AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKadEAKKAEEAKKADEAKKAEEA 1533

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  914 RKMNMANQSlKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQL 993
Cdd:PTZ00121 1534 KKADEAKKA-EEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA 1612

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  994 sEQTHKGQVRDEEVKKGKQEnerlRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSERE-- 1071
Cdd:PTZ00121 1613 -KKAEEAKIKAEELKKAEEE----KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEde 1687

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1072 -KLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTS---LNGTIEHLK---EELRSKERCLEREQQAVSQLQQLL--EN 1142
Cdd:PTZ00121 1688 kKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAeeeNKIKAEEAKkeaEEDKKKAEEAKKDEEEKKKIAHLKkeEE 1767

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1143 QKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTK---EVSKLQTEVQNTKQALKNLETREVVDMS-------- 1211
Cdd:PTZ00121 1768 KKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFAniiEGGKEGNLVINDSKEMEDSAIKEVADSKnmqleead 1847

                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 564364067 1212 ---KYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKELLHLNIEQEI 1263
Cdd:PTZ00121 1848 afeKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREI 1902
Ank_2 pfam12796
Ankyrin repeats (3 copies);
92-184 5.91e-19

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 82.86  E-value: 5.91e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067    92 LHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHgASVNAKDiDGRTPLVLATQMCRPTICQ 171
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 564364067   172 LLIDRGADVNSRD 184
Cdd:pfam12796   79 LLLEKGADINVKD 91
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 525-1348 6.68e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.58  E-value: 6.68e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   525 VIEELREQLKDMKGKYEGASaEVGKLRNQIKQSEMLVegfkrdesrLVEENKRLQKECSTCEIDRERRGRRVTELEGQLK 604
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAE-RYKELKAELRELELAL---------LVLRLEELREELEELQEELKEAEEELEELTAELQ 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   605 ELGAKLalsvptETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQhirPEEHEQLRSRLEQKSGE 684
Cdd:TIGR02168  264 ELEEKL------EELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ---LEELEAQLEELESKLDE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   685 LGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVhsltVEMKTRYVPLRVSEEMKKAhDVNVEDLNKKLSDATQRYAEKKL 764
Cdd:TIGR02168  335 LAEELAELEEKLEELKEELESLEAELEELEAEL----EELESRLEELEEQLETLRS-KVAQLELQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   765 eaERLLAENDKLTKNVSRLEAVFVAPEKHE--KELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQ 842
Cdd:TIGR02168  410 --ERLEDRRERLQQEIEELLKKLEEAELKElqAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   843 YVPAKTHEEVKASLsSTLEKTNRALLDSKKRLDDTSQEFSKL---REENE-----VLRRNLENV----QNQMKADYVSLE 910
Cdd:TIGR02168  488 QARLDSLERLQENL-EGFSEGVKALLKNQSGLSGILGVLSELisvDEGYEaaieaALGGRLQAVvvenLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   911 EHS--------------RKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKL--KYAPLSR 974
Cdd:TIGR02168  567 QNElgrvtflpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELakKLRPGYR 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   975 MEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGK 1054
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1055 QLKELSQKYSDVKSEREKLVEEKAKQTSEilaaqnllqkqpvpLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVS 1134
Cdd:TIGR02168  727 QISALRKDLARLEAEVEQLEERIAQLSKE--------------LTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIE 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1135 QLQQLLENQKSSSvtladhlqlkEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLEtrevVDMSKYK 1214
Cdd:TIGR02168  793 QLKEELKALREAL----------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELS----EDIESLA 858

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1215 ATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKELLhlniEQEIRDQKERcdkslttIMELQQRIQESAKQIEAK 1294
Cdd:TIGR02168  859 AEIEELEELIEELESELEALLNERASLEEALALLRSELEEL----SEELRELESK-------RSELRRELEELREKLAQL 927

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 564364067  1295 DNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQSQL-VDTLQQRVRDLQQQLA 1348
Cdd:TIGR02168  928 ELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDdEEEARRRLKRLENKIK 982
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
71-239 1.42e-18

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 87.70  E-value: 1.42e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   71 LNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAK 150
Cdd:COG0666     4 LLLLLLLLLAALLLLLLLALLLLAAALLLLLLLLLLLLLALLALALADALGALLLLAAALAGDLLVALLLLAAGADINAK 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  151 DIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLTLLDALGHDSSYYARIG 230
Cdd:COG0666    84 DDGGNTLLHAAARNGDLEIVKLLLEAGADVNARDKDGETPLHLAAYNGNLEIVKLLLEAGADVNAQDNDGNTPLHLAAAN 163


                  ....*....
gi 564364067  231 DNLDILNLL 239
Cdd:COG0666   164 GNLEIVKLL 172
PTZ00121 PTZ00121
MAEBL; Provisional
 453-1253 1.96e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 92.13  E-value: 1.96e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  453 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHflalkehltneaatGSHRVIEELREQ 532
Cdd:PTZ00121 1167 EEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKA--------------EDAKKAEAVKKA 1232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  533 LKDMKGKYEGASAEVGKLRNQI-KQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVTELEGQLKELGAKLA 611
Cdd:PTZ00121 1233 EEAKKDAEEAKKAEEERNNEEIrKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAE 1312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  612 LSVPTETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQhirpEEHEQLRSRLEQKSGELGKKVTE 691
Cdd:PTZ00121 1313 EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK----AEAAEKKKEEAKKKADAAKKKAE 1388

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  692 LTLKNQTLQKEVEklyaDNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLA 771
Cdd:PTZ00121 1389 EKKKADEAKKKAE----EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  772 ENDKLTKNVsrlEAVFVAPEKHEKElmGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEE 851
Cdd:PTZ00121 1465 KAEEAKKAD---EAKKKAEEAKKAD--EAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA 1539

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  852 VKASLSSTLEKTNRAllDSKKRLDDTSQEFSKLREE---NEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQD 928
Cdd:PTZ00121 1540 KKAEEKKKADELKKA--EELKKAEEKKKAEEAKKAEedkNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE 1617

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  929 AHTAL-----LADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEEcERKFKATEKALKEQLSEQTHKGQVR 1003
Cdd:PTZ00121 1618 AKIKAeelkkAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAE-EDKKKAEEAKKAEEDEKKAAEALKK 1696

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1004 DEEVKKG-----KQENERLRKdLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKElSQKYSDVKSEREKLVEEKA 1078
Cdd:PTZ00121 1697 EAEEAKKaeelkKKEAEEKKK-AEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKAEEIR 1774

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1079 KQTSEILAaqnllqkqpvpleqvealktslngtiEHLKEELRSKERCLEREQQAV-SQLQQLLENQKSSSVTLADHLQLK 1157
Cdd:PTZ00121 1775 KEKEAVIE--------------------------EELDEEDEKRRMEVDKKIKDIfDNFANIIEGGKEGNLVINDSKEME 1828

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1158 EALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKN--------LETREVVDMSKyKATKNDLETQISNLND 1229
Cdd:PTZ00121 1829 DSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFNKekdlkeddEEEIEEADEIE-KIDKDDIEREIPNNNM 1907

                         810       820
                  ....*....|....*....|....
gi 564364067 1230 KLASLNRKYDQVCEEKVSAKDEKE 1253
Cdd:PTZ00121 1908 AGKNNDIIDDKLDKDEYIKRDAEE 1931
Ank_2 pfam12796
Ankyrin repeats (3 copies);
59-151 5.08e-18

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 80.16  E-value: 5.08e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067    59 FHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTehVDLQGRTALHDAAMADCPSSIQ 138
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHADVN--LKDNGRTALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 564364067   139 LLCDHGASVNAKD 151
Cdd:pfam12796   79 LLLEKGADINVKD 91
PHA03095 PHA03095
ankyrin-like protein; Provisional
 35-203 6.82e-18

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 88.54  E-value: 6.82e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   35 EKVSSILAKKGVHPGKLDVEGRSAFHV--VAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGH--ALCLQKLLQY 110
Cdd:PHA03095  132 PKVIRLLLRKGADVNALDLYGMTPLAVllKSRNANVELLRLLIDAGADVYAVDDRFRSLLHHHLQSFKprARIVRELIRA 211

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  111 NCPTEHVDLQGRTALHDAAM-ADCPSS-IQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNR 188
Cdd:PHA03095  212 GCDPAATDMLGNTPLHSMATgSSCKRSlVLPLLIAGISINARNRYGQTPLHYAAVFNNPRACRRLIALGADINAVSSDGN 291

                         170
                  ....*....|....*
gi 564364067  189 TALMLGCEYGCRDAV 203
Cdd:PHA03095  292 TPLSLMVRNNNGRAV 306
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
617-1203 5.15e-16

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 83.96  E-value: 5.15e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  617 ETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQHIRPEEHEQLRSRLEQKSGELGKKVTELTLKN 696
Cdd:PRK03918  182 EKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKI 261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  697 QTLQKEVEKLYADNKLLNQQVHSLtvemktryvplrvsEEMKKahdvnVEDLNKKLSDATQRYAEKKLEAERLLAendKL 776
Cdd:PRK03918  262 RELEERIEELKKEIEELEEKVKEL--------------KELKE-----KAEEYIKLSEFYEEYLDELREIEKRLS---RL 319

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  777 TKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELnKKCGEGQEKIRALMSENTSLKKTLSSQyvpaktheevkasl 856
Cdd:PRK03918  320 EEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELERLKKRLTGL-------------- 384

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  857 ssTLEKTNRALLDSKKRLDDTSQEFSKLREEnevlRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDA-----HT 931
Cdd:PRK03918  385 --TPEKLEKELEELEKAKEEIEEEISKITAR----IGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKelleeYT 458

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  932 ALLADYRQGQEEIVTLHAEIKAQKKELDTIQEciklKYAPLSRMEECERKFKATEKALKEQLSEQTHKgqvRDEEVKKGK 1011
Cdd:PRK03918  459 AELKRIEKELKEIEEKERKLRKELRELEKVLK----KESELIKLKELAEQLKELEEKLKKYNLEELEK---KAEEYEKLK 531

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1012 QENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKysdvKSEREKLVEEKAKQTSEILAAQNLL 1091
Cdd:PRK03918  532 EKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEEL----GFESVEELEERLKELEPFYNEYLEL 607

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1092 QKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTladhlQLKEALEKEVGIMKASL 1171
Cdd:PRK03918  608 KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELR-----EEYLELSRELAGLRAEL 682

                         570       580       590
                  ....*....|....*....|....*....|..
gi 564364067 1172 REKEEESQKKTKEVSKLQTEVQNTKQALKNLE 1203
Cdd:PRK03918  683 EELEKRREEIKKTLEKLKEELEEREKAKKELE 714
Ank_2 pfam12796
Ankyrin repeats (3 copies);
125-217 5.76e-16

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 74.38  E-value: 5.76e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   125 LHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRgADVNSRDkQNRTALMLGCEYGCRDAVE 204
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH-ADVNLKD-NGRTALHYAARSGHLEIVK 78

                           90
                   ....*....|...
gi 564364067   205 VLVRNGADLTLLD 217
Cdd:pfam12796   79 LLLEKGADINVKD 91
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 424-1128 1.15e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 1.15e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   424 SENEILKKELEAMRTFCDSAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQkrmyESEGKVKQM 503
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELA----ELEEKLEEL 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   504 QTHFLALKEHLTNEAAT--GSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKE 581
Cdd:TIGR02168  350 KEELESLEAELEELEAEleELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKK 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   582 CStcEIDRERRGRRVTELEGQLKELGAKLalsvptETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESV 661
Cdd:TIGR02168  430 LE--EAELKELQAELEELEEELEELQEEL------ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENL 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   662 R-----------AQHIRPEEHEQLRSRLEQKSG-------ELGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVHSLTV- 722
Cdd:TIGR02168  502 EgfsegvkallkNQSGLSGILGVLSELISVDEGyeaaieaALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSi 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   723 ---EMKTRYVPLRVSEEMKKAHDVNVEDLNKKLSDATQ------RYAEKKLEAERLLAENDKLTKNVSrLEAVFVAP--- 790
Cdd:TIGR02168  582 kgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvLVVDDLDNALELAKKLRPGYRIVT-LDGDLVRPggv 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   791 -------------------EKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEE 851
Cdd:TIGR02168  661 itggsaktnssilerrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA 740

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   852 VKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMkadyvslEEHSRKMNMANQSLKEAQDAHT 931
Cdd:TIGR02168  741 EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI-------EQLKEELKALREALDELRAELT 813

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   932 ALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIklkyaplsrmeecerkfkateKALKEQLSEQTHkgqvrdeEVKKGK 1011
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQI---------------------EELSEDIESLAA-------EIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1012 QENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILA-AQNL 1090
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNlQERL 945

                          730       740       750
                   ....*....|....*....|....*....|....*...
gi 564364067  1091 LQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLER 1128
Cdd:TIGR02168  946 SEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 631-1391 2.77e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 2.77e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   631 SEKAKRLAEVGRDYESSQ-----GEIRQLKRDLESVRAQHirpEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEK 705
Cdd:TIGR02168  209 AEKAERYKELKAELRELElallvLRLEELREELEELQEEL---KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   706 LYADNKLLNQQVHSLTVEmktryvplrvsEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLAENDK----LTKNVS 781
Cdd:TIGR02168  286 LQKELYALANEISRLEQQ-----------KQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEkleeLKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   782 RLEAVFvapEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKASLSSTLE 861
Cdd:TIGR02168  355 SLEAEL---EELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   862 KTNRALLDSkkRLDDTSQEFSKLREENEVLRRNLENVQNQmkadyvsLEEHSRKMNMANQSLKEAQdahtALLADYRQGQ 941
Cdd:TIGR02168  432 EAELKELQA--ELEELEEELEELQEELERLEEALEELREE-------LEEAEQALDAAERELAQLQ----ARLDSLERLQ 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   942 EEIVTLHAEIKAQKKEldtiQECIKLKYAPLSRMEECERKF-KATEKALKEQL-------SEQTHKGQVRDEEVKKGK-- 1011
Cdd:TIGR02168  499 ENLEGFSEGVKALLKN----QSGLSGILGVLSELISVDEGYeAAIEAALGGRLqavvvenLNAAKKAIAFLKQNELGRvt 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1012 ----------QENERLRKDLAALQKELKDRNVLVEEAREAERALS------RKTEELG---KQLKELSQKYSDV------ 1066
Cdd:TIGR02168  575 flpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllggvLVVDDLDnalELAKKLRPGYRIVtldgdl 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1067 ---------------------KSEREKLVEEKAKQTSEILAAQNllqkqpvpleQVEALKTSLngtiEHLKEELRSKERC 1125
Cdd:TIGR02168  655 vrpggvitggsaktnssilerRREIEELEEKIEELEEKIAELEK----------ALAELRKEL----EELEEELEQLRKE 720

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1126 LEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLetr 1205
Cdd:TIGR02168  721 LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE--- 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1206 evvdmskykatKNDLETQISNLNDKLASLNRKYDQVCEEKvsakdekellhlnieQEIRDQKERCDKSLTtimELQQRIQ 1285
Cdd:TIGR02168  798 -----------LKALREALDELRAELTLLNEEAANLRERL---------------ESLERRIAATERRLE---DLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1286 ESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQSQLVDTLQQRVRDLQQQLADADRQHQEviaiyrthl 1365
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE--------- 919

                          810       820
                   ....*....|....*....|....*.
gi 564364067  1366 LSAAQGHMDEDVQAALLQIIQMRQGL 1391
Cdd:TIGR02168  920 LREKLAQLELRLEGLEVRIDNLQERL 945
PTZ00121 PTZ00121
MAEBL; Provisional
 507-1294 5.84e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 80.96  E-value: 5.84e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  507 FLALKEHLTNEAATGSHRVIEELReqlKDMKGKYEGASA--EVGKLRNQIKQSEmlvEGFKRDESRLVEENKRLQKECST 584
Cdd:PTZ00121 1081 FDAKEDNRADEATEEAFGKAEEAK---KTETGKAEEARKaeEAKKKAEDARKAE---EARKAEDARKAEEARKAEDAKRV 1154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  585 CEIDRERRGRRVTE---LEGQLKELGAKLALSVptETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEirQLKRDLESV 661
Cdd:PTZ00121 1155 EIARKAEDARKAEEarkAEDAKKAEAARKAEEV--RKAEELRKAEDARKAEAARKAEEERKAEEARKAE--DAKKAEAVK 1230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  662 RAQHIRPEEHEQLRSRlEQKSGELGKKVTELTLKNQTLQKEVEKlyADNKLLNQQVHSltVEMKTRYVPLRVSEEMKKAH 741
Cdd:PTZ00121 1231 KAEEAKKDAEEAKKAE-EERNNEEIRKFEEARMAHFARRQAAIK--AEEARKADELKK--AEEKKKADEAKKAEEKKKAD 1305

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  742 DVNVEDLNKKLSDATQRYAE---KKLEAERLLAENDKLTKNVSRLEAvfvapEKHEKELMGLKSNIAELKMQLCELNKKC 818
Cdd:PTZ00121 1306 EAKKKAEEAKKADEAKKKAEeakKKADAAKKKAEEAKKAAEAAKAEA-----EAAADEAEAAEEKAEAAEKKKEEAKKKA 1380

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  819 GEGQEKIRALMSENTSLKKTLSSQyvpaKTHEEVKASLSStlektnralldsKKRLDDTSQEFSKLREENEVLRRnlenv 898
Cdd:PTZ00121 1381 DAAKKKAEEKKKADEAKKKAEEDK----KKADELKKAAAA------------KKKADEAKKKAEEKKKADEAKKK----- 1439

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  899 qnqmkadyvslEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEEC 978
Cdd:PTZ00121 1440 -----------AEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEA 1508

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  979 ERKFKATEKALKEQLSEQTHKGQ--VRDEEVKKG--KQENERLRKDLAALQKELKDRnvlVEEAREAE---RALSRKTEE 1051
Cdd:PTZ00121 1509 KKKADEAKKAEEAKKADEAKKAEeaKKADEAKKAeeKKKADELKKAEELKKAEEKKK---AEEAKKAEedkNMALRKAEE 1585

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1052 LGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQpvpleqvealktslngtiehlKEELRSKERCLEREQQ 1131
Cdd:PTZ00121 1586 AKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA---------------------EEEKKKVEQLKKKEAE 1644

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1132 AVSQLQQLLENQKSSSVTlADHLQLKEALEKEvgimKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMS 1211
Cdd:PTZ00121 1645 EKKKAEELKKAEEENKIK-AAEEAKKAEEDKK----KAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAE 1719

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1212 KYKATKNDLETQISNLNDKLASLNRKYDqvcEEKVSAKDEKELLHLNIEQEIRDQKERCDKSLTTIMELQQRIQESAKQI 1291
Cdd:PTZ00121 1720 ELKKAEEENKIKAEEAKKEAEEDKKKAE---EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEV 1796


                  ...
gi 564364067 1292 EAK 1294
Cdd:PTZ00121 1797 DKK 1799
PTZ00121 PTZ00121
MAEBL; Provisional
 619-1307 1.10e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.80  E-value: 1.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  619 FESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESvRAQHIRPEEH----EQLRSRLEQKSGELGKKVTELTL 694
Cdd:PTZ00121 1081 FDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKK-KAEDARKAEEarkaEDARKAEEARKAEDAKRVEIARK 1159

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  695 KNQTLQKEVEKLYADNKLLNQQVHSLTVEmktRYVPLRVSEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLAEND 774
Cdd:PTZ00121 1160 AEDARKAEEARKAEDAKKAEAARKAEEVR---KAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAK 1236

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  775 KLTKNVSRLEAVFVAPEKHEKELMGLKSNI-------AELKMQLCELnKKCGEGQEKIRALMSENTSLKKTLSSQYVPAK 847
Cdd:PTZ00121 1237 KDAEEAKKAEEERNNEEIRKFEEARMAHFArrqaaikAEEARKADEL-KKAEEKKKADEAKKAEEKKKADEAKKKAEEAK 1315

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  848 THEEVKASLSSTLEKTNRAlldsKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQ 927
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAA----KKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKK 1391

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  928 DAHTALL-ADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEE 1006
Cdd:PTZ00121 1392 KADEAKKkAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1007 VKKGKQENERLRKdLAALQKELKDRNVLVEEAREAERAlSRKTEELGKqlKELSQKYSDVKSEREKLVEEKAKQTSEILA 1086
Cdd:PTZ00121 1472 ADEAKKKAEEAKK-ADEAKKKAEEAKKKADEAKKAAEA-KKKADEAKK--AEEAKKADEAKKAEEAKKADEAKKAEEKKK 1547

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1087 AQNLlqKQPVPLEQVEALKTslngtIEHLKEELRSKERCLEREQQAvSQLQQLLENQKSSSVTLADHLQLKEALEKEVGI 1166
Cdd:PTZ00121 1548 ADEL--KKAEELKKAEEKKK-----AEEAKKAEEDKNMALRKAEEA-KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1167 MKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKV 1246
Cdd:PTZ00121 1620 IKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE 1699

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564364067 1247 SAKDEKELLHLNIEQEIRDQKERCDKSLTTIM--------ELQQRIQESAKQIEAKDNKITELLNDVER 1307
Cdd:PTZ00121 1700 EAKKAEELKKKEAEEKKKAEELKKAEEENKIKaeeakkeaEEDKKKAEEAKKDEEEKKKIAHLKKEEEK 1768
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 525-1312 1.25e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 1.25e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   525 VIEELREQLKDMKG------KYEGASAEVGKLR-----NQIKQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRG 593
Cdd:TIGR02169  192 IIDEKRQQLERLRRerekaeRYQALLKEKREYEgyellKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   594 RRVTELEGQLKELGAKLALSVPTE--TFESMKSSLSNDISEKAKRLaevgrdyESSQGEIRQLKRDLESVRaqhirpEEH 671
Cdd:TIGR02169  272 QLLEELNKKIKDLGEEEQLRVKEKigELEAEIASLERSIAEKEREL-------EDAEERLAKLEAEIDKLL------AEI 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   672 EQLRSRLEQKSGELGKkvteltlknqtLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRvseemkkahdvnveDLNKK 751
Cdd:TIGR02169  339 EELEREIEEERKRRDK-----------LTEEYAELKEELEDLRAELEEVDKEFAETRDELK--------------DYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   752 LSDATQRYAEKKLEAERLLAENDKLTKNVSRLEAvfvapekhekELMGLKSNIAELKMQLCELnkkcgegQEKIRALMSE 831
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNA----------AIAGIEAKINELEEEKEDK-------ALEIKKQEWK 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   832 NTSLKKTLSSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQM------KAD 905
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVaqlgsvGER 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   906 YVSLEEHSRKMNMANQSLKEAQDAHTA--LLADYRQGQEEIVTLHaEIKAQKKELDTIQECIKLKYAplSRMEECERKF- 982
Cdd:TIGR02169  537 YATAIEVAAGNRLNNVVVEDDAVAKEAieLLKRRKAGRATFLPLN-KMRDERRDLSILSEDGVIGFA--VDLVEFDPKYe 613

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   983 KATEKALKEQL------SEQTHKGQVR----DEEV---------------------KKGKQENERLRKDLAALQKELkdr 1031
Cdd:TIGR02169  614 PAFKYVFGDTLvvedieAARRLMGKYRmvtlEGELfeksgamtggsraprggilfsRSEPAELQRLRERLEGLKREL--- 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1032 NVLVEEAREAERALSrkteELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEAlktslngT 1111
Cdd:TIGR02169  691 SSLQSELRRIENRLD----ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS-------E 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1112 IEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTladhlQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTE 1191
Cdd:TIGR02169  760 LKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQ-----AELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1192 VQNTKQALKNLETRevvdmskykatKNDLETQISNLNDKLASLNRKydqvCEEKVSAKDEKELLHLNIEQEIRDQKERcd 1271
Cdd:TIGR02169  835 IQELQEQRIDLKEQ-----------IKSIEKEIENLNGKKEELEEE----LEELEAALRDLESRLGDLKKERDELEAQ-- 897

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|.
gi 564364067  1272 kslttIMELQQRIQESAKQIEAKDNKITELLNDVERLKQAL 1312
Cdd:TIGR02169  898 -----LRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 467-1272 1.40e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 79.34  E-value: 1.40e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   467 ECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTH------FLALKEHLTNEAATGSHRVIEELREQLKDMKGKY 540
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRErekaerYQALLKEKREYEGYELLKEKEALERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   541 EGASAEVGKLRNQIKQSE--------MLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVTELEGQLKELGAKLA- 611
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEkrleeieqLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAk 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   612 LSVPTETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQHIRP-EEHEQLRSRLEQKSGELGKKVT 690
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETrDELKDYREKLEKLKREINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   691 ELTLKNQTLQK---EVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEmkkahdvNVEDLNKKLSDATQRYAEKKLEAE 767
Cdd:TIGR02169  407 ELDRLQEELQRlseELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW-------KLEQLAADLSKYEQELYDLKEEYD 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   768 RLLAENDKLTKNVSRLEAVFVAPEKHEKE----LMGLKSNIAELKMQLCELnkkcgeGQEKIRALMSENTSLKKTLssQY 843
Cdd:TIGR02169  480 RVEKELSKLQRELAEAEAQARASEERVRGgravEEVLKASIQGVHGTVAQL------GSVGERYATAIEVAAGNRL--NN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   844 VPAKThEEVKASLSSTL--EKTNRALLDSKKRLDDTSQEFSKLREE-------------------------NEVLRRNLE 896
Cdd:TIGR02169  552 VVVED-DAVAKEAIELLkrRKAGRATFLPLNKMRDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgDTLVVEDIE 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   897 NVQNQM-KADYVSLE----EHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQeciKLKYAP 971
Cdd:TIGR02169  631 AARRLMgKYRMVTLEgelfEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIE---NRLDEL 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   972 LSRMEECERKFKATEKALkEQLSEQTHKGQVRDEEVK----KGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSR 1047
Cdd:TIGR02169  708 SQELSDASRKIGEIEKEI-EQLEQEEEKLKERLEELEedlsSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1048 KteELGKQLKELSQKYSDVKSEREKLVE-------EKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELR 1120
Cdd:TIGR02169  787 R--LSHSRIPEIQAELSKLEEEVSRIEArlreieqKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1121 SKERCLEREQQAVSQLQQLLENQKSSsvtladhlqlKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALK 1200
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKE----------RDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS 934

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1201 NLE---------TREVVDMSKYKATKNDLETQISnlndKLASLNRKYDQVCEEKVSAKDEKELLHLNIEQEIRDQKERCD 1271
Cdd:TIGR02169  935 EIEdpkgedeeiPEEELSLEDVQAELQRVEEEIR----ALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIE 1010


                   .
gi 564364067  1272 K 1272
Cdd:TIGR02169 1011 E 1011
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
744-1318 2.10e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 78.57  E-value: 2.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  744 NVEDLNKKLSDATQRYAEKKLEAERLLAENDKLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQE 823
Cdd:PRK03918  180 RLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEE 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  824 KIRALMSENTSLKKTLssqyvpaKTHEEVKASLSStLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMK 903
Cdd:PRK03918  260 KIRELEERIEELKKEI-------EELEEKVKELKE-LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  904 adyvSLEEHSRKMNMANQSLKEAQDAHTALladyrqgqEEIVTLHAEIKAQKKELdtiqECIKLKYAPLSrMEECERKFK 983
Cdd:PRK03918  332 ----ELEEKEERLEELKKKLKELEKRLEEL--------EERHELYEEAKAKKEEL----ERLKKRLTGLT-PEKLEKELE 394

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  984 ATEKAlKEQLSEQTHKGQVRDEEVkkgKQENERLRKDLAALQKE-----LKDRNVLVEEAREAERALSRKTEELGKQLKE 1058
Cdd:PRK03918  395 ELEKA-KEEIEEEISKITARIGEL---KKEIKELKKAIEELKKAkgkcpVCGRELTEEHRKELLEEYTAELKRIEKELKE 470

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1059 LSQKYSDVKSEREKlVEEKAKQTSEILAAQNLlqkqpvpLEQVEALKTSLNG-TIEHLK------EELRSKERCLEREQQ 1131
Cdd:PRK03918  471 IEEKERKLRKELRE-LEKVLKKESELIKLKEL-------AEQLKELEEKLKKyNLEELEkkaeeyEKLKEKLIKLKGEIK 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1132 AVSQLQQLLENQKSSSVTLADHLQ-LKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREvvdm 1210
Cdd:PRK03918  543 SLKKELEKLEELKKKLAELEKKLDeLEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREE---- 618

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1211 SKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKELLHLNIEQEIRDQKERCDKSLTTIMELQQRIQESAKQ 1290
Cdd:PRK03918  619 KELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEK 698

                         570       580
                  ....*....|....*....|....*...
gi 564364067 1291 IEAKDNKITELLNDVERLKQALNGLSQL 1318
Cdd:PRK03918  699 LKEELEEREKAKKELEKLEKALERVEEL 726
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 62-214 2.80e-14

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 77.99  E-value: 2.80e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   62 VAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLC 141
Cdd:PLN03192  532 VASTGNAALLEELLKAKLDPDIGDSKGRTPLHIAASKGYEDCVLVLLKHACNVHIRDANGNTALWNAISAKHHKIFRILY 611

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564364067  142 dHGASVNAKDIDGRTpLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLT 214
Cdd:PLN03192  612 -HFASISDPHAAGDL-LCTAAKRNDLTAMKELLKQGLNVDSEDHQGATALQVAMAEDHVDMVRLLIMNGADVD 682
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 794-1313 3.75e-14

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 77.37  E-value: 3.75e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   794 EKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKR 873
Cdd:TIGR04523   39 EKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQ 118

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   874 LDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKA 953
Cdd:TIGR04523  119 KNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLK 198

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   954 QKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKE---QLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKD 1030
Cdd:TIGR04523  199 LELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKkqqEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQ 278

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1031 RNVLVEEAREAERALSRKTEELGKQLKELSQKysDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNG 1110
Cdd:TIGR04523  279 NNKKIKELEKQLNQLKSEISDLNNQKEQDWNK--ELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSES 356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1111 TIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEVGImkaSLREKEEESQKKTKEVSKLQT 1190
Cdd:TIGR04523  357 ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDE---QIKKLQQEKELLEKEIERLKE 433

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1191 EVQNTKQALKNLETREVVDMSKYK---ATKNDLETQISNLNDKLASLNRKYDQVCEEKVSakDEKELLHLNieQEIRDQK 1267
Cdd:TIGR04523  434 TIIKNNSEIKDLTNQDSVKELIIKnldNTRESLETQLKVLSRSINKIKQNLEQKQKELKS--KEKELKKLN--EEKKELE 509

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 564364067  1268 ERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALN 1313
Cdd:TIGR04523  510 EKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELK 555
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 33-181 8.49e-14

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 75.09  E-value: 8.49e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   33 DVEKVSSILAKKGVHPGKLDVEGRSAFHVVAAK--GNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHA------LCL 104
Cdd:PHA03100   84 DVKEIVKLLLEYGANVNAPDNNGITPLLYAISKksNSYSIVEYLLDNGANVNIKNSDGENLLHLYLESNKIdlkilkLLI 163

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  105 QK------------LLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQL 172
Cdd:PHA03100  164 DKgvdinaknrvnyLLSYGVPINIKDVYGFTPLHYAVYNNNPEFVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKL 243


                  ....*....
gi 564364067  173 LIDRGADVN 181
Cdd:PHA03100  244 LLNNGPSIK 252
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 74-213 2.03e-13

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 75.10  E-value: 2.03e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   74 ILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCP-SSIQLLCDHGASVNAKDI 152
Cdd:PHA02876  361 LLELGANVNARDYCDKTPIHYAAVRNNVVIINTLLDYGADIEALSQKIGTALHFALCGTNPyMSVKTLIDRGANVNSKNK 440

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564364067  153 DGRTPLVLATQM-CRPTICQLLIDRGADVNSRDKQNRTALMLGCEYgcRDAVEVLVRNGADL 213
Cdd:PHA02876  441 DLSTPLHYACKKnCKLDVIEMLLDNGADVNAINIQNQYPLLIALEY--HGIVNILLHYGAEL 500
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 429-1195 2.06e-13

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 75.54  E-value: 2.06e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   429 LKKELEAMRTFCDSAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLedalkdvQKRMYESEGKVKQMQTHFL 508
Cdd:pfam15921  122 MQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQL-------RKMMLSHEGVLQEIRSILV 194

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   509 ALKEHLTNEAATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEenKRLQKEcstceid 588
Cdd:pfam15921  195 DFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIE--LLLQQH------- 265

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   589 RERRGRRVTELEGQLKELgaklalsvpTETFESMKSSlSNDISEKAKRLAEVGRDYESSQgeIRQLKrDLESVRAQhIRP 668
Cdd:pfam15921  266 QDRIEQLISEHEVEITGL---------TEKASSARSQ-ANSIQSQLEIIQEQARNQNSMY--MRQLS-DLESTVSQ-LRS 331

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   669 EEHEQLRSrLEQKSGELGKkvtELTLKNQTL---QKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMkkahdvnv 745
Cdd:pfam15921  332 ELREAKRM-YEDKIEELEK---QLVLANSELteaRTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQ-------- 399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   746 edlNKKLSDatqRYAEKKLEAERLLAENDKLTKNVSRLEAVFVAPE-----KHEKELMGLKSNIAELKmQLCELNKKCGE 820
Cdd:pfam15921  400 ---NKRLWD---RDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKsecqgQMERQMAAIQGKNESLE-KVSSLTAQLES 472

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   821 GQEKIRALMSENTSLKKTLSSQyvpAKTHEEVKASLSS---TLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRrnleN 897
Cdd:pfam15921  473 TKEMLRKVVEELTAKKMTLESS---ERTVSDLTASLQEkerAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLR----N 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   898 VQNQMKADYVSLEEHSRKMNMANQSLKE-----AQDAHTALLADYRQGQeeivtLHAEIKAQKKELdtiQECIKLKYAPL 972
Cdd:pfam15921  546 VQTECEALKLQMAEKDKVIEILRQQIENmtqlvGQHGRTAGAMQVEKAQ-----LEKEINDRRLEL---QEFKILKDKKD 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   973 SRMEECERKFkateKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELkdrNVLVEEAREAERALSRKTEEL 1052
Cdd:pfam15921  618 AKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNEL---NSLSEDYEVLKRNFRNKSEEM 690

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1053 GKQLKELSQKYSDVKSE----REKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSlngtIEHLKEELR--SKERCL 1126
Cdd:pfam15921  691 ETTTNKLKMQLKSAQSEleqtRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK----IQFLEEAMTnaNKEKHF 766

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564364067  1127 EREQQavSQLQQLLENQKSSSVTLADHLQLKEALEK---------EVGIMKASLREKEEESQKKTKEVSKLQTEVQNT 1195
Cdd:pfam15921  767 LKEEK--NKLSQELSTVATEKNKMAGELEVLRSQERrlkekvanmEVALDKASLQFAECQDIIQRQEQESVRLKLQHT 842
PHA03095 PHA03095
ankyrin-like protein; Provisional
 29-239 2.34e-13

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 74.29  E-value: 2.34e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   29 AERGDVEKVSSILAKKGvhpgklDVE-----GRSAFHVVAAKGN---LECLNAILTHGIDVATRDSAGRNALHLAAKYGH 100
Cdd:PHA03095   22 ASNVTVEEVRRLLAAGA------DVNfrgeyGKTPLHLYLHYSSekvKDIVRLLLEAGADVNAPERCGFTPLHLYLYNAT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  101 ALCLQKLL-QYNCPTEHVDLQGRTALHDAAMADC--PSSIQLLCDHGASVNAKDIDGRTPL--VLATQMCRPTICQLLID 175
Cdd:PHA03095   96 TLDVIKLLiKAGADVNAKDKVGRTPLHVYLSGFNinPKVIRLLLRKGADVNALDLYGMTPLavLLKSRNANVELLRLLID 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  176 RGADVNSRDKQNRTALMLGCEYgCRD---AVEVLVRNGADLTLLDALGHDSSYYARIGD---NLDILNLL 239
Cdd:PHA03095  176 AGADVYAVDDRFRSLLHHHLQS-FKPrarIVRELIRAGCDPAATDMLGNTPLHSMATGSsckRSLVLPLL 244
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
524-1141 2.52e-13

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 75.10  E-value: 2.52e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  524 RVIEELREQLKDMKGKYEGASAEVGKLrnqikqsemlvEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVTELEGQL 603
Cdd:PRK03918  207 REINEISSELPELREELEKLEKEVKEL-----------EELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEI 275

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  604 KELGAKLAlsvptetfesmkssLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQHIRPEEHEQLRSRLEQKSG 683
Cdd:PRK03918  276 EELEEKVK--------------ELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLE 341

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  684 ELGKKVTEltlknqtLQKEVEKLYADNKLLnqqvhsltvemktryvplrvseEMKKAHDVNVEDLNKKLSDATQRYAEKK 763
Cdd:PRK03918  342 ELKKKLKE-------LEKRLEELEERHELY----------------------EEAKAKKEELERLKKRLTGLTPEKLEKE 392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  764 LEAerLLAENDKLTKNVSRLEAvfvapekhekELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENtslKKTLSSQY 843
Cdd:PRK03918  393 LEE--LEKAKEEIEEEISKITA----------RIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEH---RKELLEEY 457

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  844 vpaktHEEVKaSLSSTLEKTNRALLDSKKRLddtsQEFSKLREENEVLRRNLEnVQNQMKadyvSLEEHSRKMNmanqsL 923
Cdd:PRK03918  458 -----TAELK-RIEKELKEIEEKERKLRKEL----RELEKVLKKESELIKLKE-LAEQLK----ELEEKLKKYN-----L 517

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  924 KEAQDAHTallaDYRQGQEEIVTLHAEIKAQKKELDTIQECIKlkyaplsRMEECERKFKATEKALKEQLSEQTHKGQVR 1003
Cdd:PRK03918  518 EELEKKAE----EYEKLKEKLIKLKGEIKSLKKELEKLEELKK-------KLAELEKKLDELEEELAELLKELEELGFES 586

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1004 DEEVKKGKQENERL----------RKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDvkSEREKL 1073
Cdd:PRK03918  587 VEELEERLKELEPFyneylelkdaEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSE--EEYEEL 664

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564364067 1074 VEEKAKQTSEILAAQNllqkqpvPLEQVEALKTSLNGTIEHLKEEL---RSKERCLEREQQAVSQLQQLLE 1141
Cdd:PRK03918  665 REEYLELSRELAGLRA-------ELEELEKRREEIKKTLEKLKEELeerEKAKKELEKLEKALERVEELRE 728
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 684-1309 3.17e-13

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 74.67  E-value: 3.17e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   684 ELGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKLSdatqryaEKK 763
Cdd:TIGR04523   79 ILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIK-------KKE 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   764 LEAERLLAENDKLTKNVSRLEAVFvapEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIralmSENTSLKKTLSSQy 843
Cdd:TIGR04523  152 KELEKLNNKYNDLKKQKEELENEL---NLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKI----QKNKSLESQISEL- 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   844 vpakthEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQmkadyvsLEEHSRKMNMANQSL 923
Cdd:TIGR04523  224 ------KKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKE-------LEQNNKKIKELEKQL 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   924 KEAQdahTALLADYRQGQEEIV-TLHAEIKAQKKELDTIQeciklkyAPLSRMEECERKFKATEKALKEQLSEQTHKGQV 1002
Cdd:TIGR04523  291 NQLK---SEISDLNNQKEQDWNkELKSELKNQEKKLEEIQ-------NQISQNNKIISQLNEQISQLKKELTNSESENSE 360

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1003 RDEEVKKGKQENERLRKDLAALQKELKDrnvlveeareaeralsrkteeLGKQLKELSQKYSDVKSEREKLVEEKAKQTS 1082
Cdd:TIGR04523  361 KQRELEEKQNEIEKLKKENQSYKQEIKN---------------------LESQINDLESKIQNQEKLNQQKDEQIKKLQQ 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1083 EilaaQNLLQKQpvpLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLEnqksssvtladhlqlkeALEK 1162
Cdd:TIGR04523  420 E----KELLEKE---IERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLK-----------------VLSR 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1163 EVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETRevvdMSKYKATKNDLETQISNLNDKLASLNRKYDQVC 1242
Cdd:TIGR04523  476 SINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKK----ISSLKEKIEKLESEKKEKESKISDLEDELNKDD 551

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564364067  1243 EEKVSAKDEKELLHLNieQEIRDQKERCDKSLTTIMELQQRIQESA-------KQIEAKDNKITELLNDVERLK 1309
Cdd:TIGR04523  552 FELKKENLEKEIDEKN--KEIEELKQTQKSLKKKQEEKQELIDQKEkekkdliKEIEEKEKKISSLEKELEKAK 623
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 650-1316 3.94e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 74.72  E-value: 3.94e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   650 EIRQLKRDLESVRaqhirpEEHEQLRSRLEQKSGELGK--KVTELTLKNQTLQKEVEKLYADNKLLNQQVHsltvemktr 727
Cdd:TIGR02169  171 KKEKALEELEEVE------ENIERLDLIIDEKRQQLERlrREREKAERYQALLKEKREYEGYELLKEKEAL--------- 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   728 yvplrvsEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLAENDKLTKNVSRL---EAVFVAPEKHE--KELMGLKS 802
Cdd:TIGR02169  236 -------ERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeEQLRVKEKIGEleAEIASLER 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   803 NIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFS 882
Cdd:TIGR02169  309 SIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   883 KLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALladyrqgQEEIVTLHAEIKAQKKELDTIQ 962
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINEL-------EEEKEDKALEIKKQEWKLEQLA 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   963 ECIKLKYAPLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDL------------------AAL 1024
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIqgvhgtvaqlgsvgeryaTAI 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1025 QKELKDR--NVLVEEAREAERALS-RKTEELGK-----------------------------QLKELSQKY--------- 1063
Cdd:TIGR02169  542 EVAAGNRlnNVVVEDDAVAKEAIElLKRRKAGRatflplnkmrderrdlsilsedgvigfavDLVEFDPKYepafkyvfg 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1064 -----SDVKSERE------------KLVEEKAKQTSEILAAQNLLQKQPVPLEQVEalktSLNGTIEHLKEELRSKERCL 1126
Cdd:TIGR02169  622 dtlvvEDIEAARRlmgkyrmvtlegELFEKSGAMTGGSRAPRGGILFSRSEPAELQ----RLRERLEGLKRELSSLQSEL 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1127 EREQQAVSQLQQLLENQKSSSVTL-ADHLQLKEALEKEVGIMKASLREKEEESQKKT----------KEVSKLQTEVQNT 1195
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEnvkselkeleARIEELEEDLHKL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1196 KQALKNLETREvvDMSKYK---ATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKEllhlNIEQEIRDQKERcdk 1272
Cdd:TIGR02169  778 EEALNDLEARL--SHSRIPeiqAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQ----ELQEQRIDLKEQ--- 848

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 564364067  1273 slttIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLS 1316
Cdd:TIGR02169  849 ----IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLK 888
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 292-1075 4.85e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 74.32  E-value: 4.85e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   292 DLKEKLRKIQQeqRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHpgpg 371
Cdd:TIGR02168  217 ELKAELRELEL--ALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL---- 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   372 sYSSNRKEDMLHKQGQMYTADsqctspgvpphmQSRSMLRPLELSLPSQTSYSENEILKKELEAMRTFCDSAKQDRLKLQ 451
Cdd:TIGR02168  291 -YALANEISRLEQQKQILRER------------LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   452 NELAHKVAECKALalecERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNEAATGS--------- 522
Cdd:TIGR02168  358 AELEELEAELEEL----ESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEellkkleea 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   523 -----HRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRL----------VEENKRLQKECSTCEI 587
Cdd:TIGR02168  434 elkelQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLqarldslerlQENLEGFSEGVKALLK 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   588 DRERRGRRVTELEGQLK-----ELGAKLAL-----SVPTETFESMKSSLSNDISEKAKRLA------EVGRDYESSQGEI 651
Cdd:TIGR02168  514 NQSGLSGILGVLSELISvdegyEAAIEAALggrlqAVVVENLNAAKKAIAFLKQNELGRVTflpldsIKGTEIQGNDREI 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   652 RQLKR-------DLESVR----------------------AQHIRPEEHEQLR-----SRLEQKSGELGKKVTELTLKNQ 697
Cdd:TIGR02168  594 LKNIEgflgvakDLVKFDpklrkalsyllggvlvvddldnALELAKKLRPGYRivtldGDLVRPGGVITGGSAKTNSSIL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   698 TLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLAENDKLT 777
Cdd:TIGR02168  674 ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   778 KNVSRLEAvfvapekhekELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKASLS 857
Cdd:TIGR02168  754 KELTELEA----------EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   858 STLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADY 937
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEEL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   938 RQGQEEIVTLHAEIKAQKKELDTIQEciklkyaplsRMEecerKFKATEKALKEQLSEQTH-KGQVRDEEVKKGKQENER 1016
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLEL----------RLE----GLEVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEE 969

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 564364067  1017 LRKDLAALQKELKDRNVLVEEAREAeralsrkTEELGKQLKELSQKYSDVKSEREKLVE 1075
Cdd:TIGR02168  970 ARRRLKRLENKIKELGPVNLAAIEE-------YEELKERYDFLTAQKEDLTEAKETLEE 1021
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1026-1391 6.81e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 6.81e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1026 KELKDRnvlvEEAREAERALSRKtEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQpvpLEQVEALK 1105
Cdd:COG1196   216 RELKEE----LKELEAELLLLKL-RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEEL---ELELEEAQ 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1106 TSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEV 1185
Cdd:COG1196   288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1186 SKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDQVcEEKVSAKDEKELLHLNIEQEIRD 1265
Cdd:COG1196   368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL-EELEEALAELEEEEEEEEEALEE 446

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1266 QKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTyssggpTKRQSQLVDTLQQRVRDLQQ 1345
Cdd:COG1196   447 AAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE------ADYEGFLEGVKAALLLAGLR 520

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 564364067 1346 QLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGL 1391
Cdd:COG1196   521 GLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 25-248 1.36e-12

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 71.53  E-value: 1.36e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   25 LMKAAERGDVEKVSSILaKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCL 104
Cdd:PHA02874  128 LHYAIKKGDLESIKMLF-EYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYANVKDNNGESPLHNAAEYGDYACI 206

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  105 QKLLQYncpTEHVDLQ---GRTALHDAAMADcPSSIQLLCDHgASVNAKDIDGRTPLVLATQM-CRPTICQLLIDRGADV 180
Cdd:PHA02874  207 KLLIDH---GNHIMNKcknGFTPLHNAIIHN-RSAIELLINN-ASINDQDIDGSTPLHHAINPpCDIDIIDILLYHKADI 281

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564364067  181 NSRDKQNRTALMLGCEYGCRDAV-------EVLVRNGADLTLLDALGHDSsyyarIGDNLDILNLLKTASESTSK 248
Cdd:PHA02874  282 SIKDNKGENPIDTAFKYINKDPVikdiianAVLIKEADKLKDSDFLEHIE-----IKDNKEFSDFIKECNEEIED 351
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 453-1185 4.12e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.25  E-value: 4.12e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   453 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNEAAtgshrVIEELREQ 532
Cdd:TIGR02169  298 ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE-----ELEDLRAE 372

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   533 LKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVTELEGQLKELGAKLal 612
Cdd:TIGR02169  373 LEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEI-- 450

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   613 svptETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESV--RAQHIRPEEHEQLRSRLEQKSGELG--KK 688
Cdd:TIGR02169  451 ----KKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAeaQARASEERVRGGRAVEEVLKASIQGvhGT 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   689 VTELTLKNQTLQKEVEkLYADNKLLNQQVHSLTVE------MKTR------YVPLRvseEMKKAHdvnvEDLNKKLSDAT 756
Cdd:TIGR02169  527 VAQLGSVGERYATAIE-VAAGNRLNNVVVEDDAVAkeaielLKRRkagratFLPLN---KMRDER----RDLSILSEDGV 598

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   757 QRYA------EKKLEAERLLAENDKLTknVSRLEA----------VFVAPEKHEK---------ELMGLKSNIAELKMQL 811
Cdd:TIGR02169  599 IGFAvdlvefDPKYEPAFKYVFGDTLV--VEDIEAarrlmgkyrmVTLEGELFEKsgamtggsrAPRGGILFSRSEPAEL 676

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   812 CELNKKCGEGQEKIRALMSENTSLKKTLSsqyvpaktheevkaSLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVL 891
Cdd:TIGR02169  677 QRLRERLEGLKRELSSLQSELRRIENRLD--------------ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEL 742

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   892 RRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQ-EEIVTLHAEIKAQKKELDTIQECIKLKYA 970
Cdd:TIGR02169  743 EEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIEQKLN 822

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   971 PLSRMEECERKFKATEKALKEQLSEQthkgqvRDEEvkkgKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTE 1050
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIDLKEQ------IKSI----EKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERD 892

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1051 ELGKQLKELSQKYSDVKSEREKLvEEKAKQTSEILAA--QNLLQKQPVPLEQVEALKTSLngTIEHLKEELRSkercLER 1128
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKK-RKRLSELKAKLEAleEELSEIEDPKGEDEEIPEEEL--SLEDVQAELQR----VEE 965

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 564364067  1129 EQQAVSQLQQLLENQKSSSVTLADHLQLKEA-LEKEvgimKASLREKEEESQKKTKEV 1185
Cdd:TIGR02169  966 EIRALEPVNMLAIQEYEEVLKRLDELKEKRAkLEEE----RKAILERIEEYEKKKREV 1019
Ank_2 pfam12796
Ankyrin repeats (3 copies);
25-112 4.24e-12

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 63.60  E-value: 4.24e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067    25 LMKAAERGDVEKVSsILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIdvATRDSAGRNALHLAAKYGHALCL 104
Cdd:pfam12796    1 LHLAAKNGNLELVK-LLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHAD--VNLKDNGRTALHYAARSGHLEIV 77


                   ....*...
gi 564364067   105 QKLLQYNC 112
Cdd:pfam12796   78 KLLLEKGA 85
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 67-239 4.95e-12

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 69.69  E-value: 4.95e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   67 NLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQK-----LLQYNCPTEHVDLQGRTALHDAAMADC--PSSIQL 139
Cdd:PHA03100   47 NIDVVKILLDNGADINSSTKNNSTPLHYLSNIKYNLTDVKeivklLLEYGANVNAPDNNGITPLLYAISKKSnsYSIVEY 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  140 LCDHGASVNAKDIDGRTPLVLATQMCRPT--ICQLLIDRGADVN----------------SRDKQNRTALMLGCEYGCRD 201
Cdd:PHA03100  127 LLDNGANVNIKNSDGENLLHLYLESNKIDlkILKLLIDKGVDINaknrvnyllsygvpinIKDVYGFTPLHYAVYNNNPE 206

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 564364067  202 AVEVLVRNGADLTLLDALGHDSSYYARIGDNLDILNLL 239
Cdd:PHA03100  207 FVKYLLDLGANPNLVNKYGDTPLHIAILNNNKEIFKLL 244
PHA03095 PHA03095
ankyrin-like protein; Provisional
 32-232 6.15e-12

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 69.67  E-value: 6.15e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   32 GDVEKVSSILAKKGVHPGKLDVEGRSAFHVVAAKGN-LECLNAILTHGIDVATRDSAGRNALH--LAAKYGHALCLQKLL 108
Cdd:PHA03095   60 EKVKDIVRLLLEAGADVNAPERCGFTPLHLYLYNATtLDVIKLLIKAGADVNAKDKVGRTPLHvyLSGFNINPKVIRLLL 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  109 QYNCPTEHVDLQGRTALH------DAamadCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRP--TICQLLIDRGADV 180
Cdd:PHA03095  140 RKGADVNALDLYGMTPLAvllksrNA----NVELLRLLIDAGADVYAVDDRFRSLLHHHLQSFKPraRIVRELIRAGCDP 215

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 564364067  181 NSRDKQNRTALMLGCEYG-CRDA-VEVLVRNGADLTLLDALGHDSSYYARIGDN 232
Cdd:PHA03095  216 AATDMLGNTPLHSMATGSsCKRSlVLPLLIAGISINARNRYGQTPLHYAAVFNN 269
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 921-1217 8.18e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 70.35  E-value: 8.18e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  921 QSLKEAQDA--HTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAplsRMEECERKFKATEKALKEQLSEQTH 998
Cdd:COG1196   216 RELKEELKEleAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEA---ELEELRLELEELELELEEAQAEEYE 292

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  999 KGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKA 1078
Cdd:COG1196   293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1079 KQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKE 1158
Cdd:COG1196   373 ELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA 452

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564364067 1159 ALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATK 1217
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
447-992 9.49e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 69.71  E-value: 9.49e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  447 RLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQ------THFLALKEHLTN---- 516
Cdd:PRK03918  229 EVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEylde 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  517 -----EAATGSHRVIEELREQLKDMKGKyegaSAEVGKLRNQIKQSEMLVEGFKRDEsRLVEENKRLQKECStcEIDRER 591
Cdd:PRK03918  309 lreieKRLSRLEEEINGIEERIKELEEK----EERLEELKKKLKELEKRLEELEERH-ELYEEAKAKKEELE--RLKKRL 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  592 RGRRVTELEGQLKEL-GAKLALSVPTETFESMKSSLSNDISEKAKRLAEVgrdyESSQGEIRQLKRDLESvraqhirpEE 670
Cdd:PRK03918  382 TGLTPEKLEKELEELeKAKEEIEEEISKITARIGELKKEIKELKKAIEEL----KKAKGKCPVCGRELTE--------EH 449

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  671 HEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLyaDNKLLNQqvhSLTVEMKTRYVPLRVSEEMKKAHdvNVEDLNK 750
Cdd:PRK03918  450 RKELLEEYTAELKRIEKELKEIEEKERKLRKELREL--EKVLKKE---SELIKLKELAEQLKELEEKLKKY--NLEELEK 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  751 klsdatqryaeKKLEAERLLAENDKLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGE-GQEKIRALM 829
Cdd:PRK03918  523 -----------KAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEElGFESVEELE 591

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  830 SENTSLKKtLSSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLenvqnqmkadyvSL 909
Cdd:PRK03918  592 ERLKELEP-FYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKY------------SE 658

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  910 EEHSRKMNMAnQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKAL 989
Cdd:PRK03918  659 EEYEELREEY-LELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALL 737


                  ...
gi 564364067  990 KEQ 992
Cdd:PRK03918  738 KER 740
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
766-1357 1.01e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 69.71  E-value: 1.01e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  766 AERLLAENDKLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTlssqyvp 845
Cdd:PRK03918  164 YKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL------- 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  846 aktheevkASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKadyvsleehsrkmnmanqSLKE 925
Cdd:PRK03918  237 --------KEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELK------------------ELKE 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  926 AQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQlsEQTHKGQvrdE 1005
Cdd:PRK03918  291 KAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL--EERHELY---E 365

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1006 EVKKGKQENERLRKDLAALQKElkDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLveEKAKQTSEIL 1085
Cdd:PRK03918  366 EAKAKKEELERLKKRLTGLTPE--KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEEL--KKAKGKCPVC 441

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1086 AAQ-------NLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQaVSQLQQLLEnqksssvtladhlQLKE 1158
Cdd:PRK03918  442 GRElteehrkELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE-LIKLKELAE-------------QLKE 507

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1159 ALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREvVDMSKYKATKNDLETQISNLNDKLASLNRKY 1238
Cdd:PRK03918  508 LEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK-KKLAELEKKLDELEEELAELLKELEELGFES 586

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1239 DQVCEEKVSAKDE--KELLHL-NIEQEIRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELL-----NDVERLKQ 1310
Cdd:PRK03918  587 VEELEERLKELEPfyNEYLELkDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEkkyseEEYEELRE 666

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*..
gi 564364067 1311 ALNGLSQLTYSSGGPTKRQSQLVDTLQQRVRDLQQQLADADRQHQEV 1357
Cdd:PRK03918  667 EYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKEL 713
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 35-222 1.17e-11

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 68.45  E-value: 1.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   35 EKVSSILaKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPT 114
Cdd:PHA02874  105 DMIKTIL-DCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAYA 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  115 EHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTIcQLLIDrGADVNSRDKQNRTALMLG 194
Cdd:PHA02874  184 NVKDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIIHNRSAI-ELLIN-NASINDQDIDGSTPLHHA 261

                         170       180
                  ....*....|....*....|....*....
gi 564364067  195 CEYGC-RDAVEVLVRNGADLTLLDALGHD 222
Cdd:PHA02874  262 INPPCdIDIIDILLYHKADISIKDNKGEN 290
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 469-1296 2.05e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 68.99  E-value: 2.05e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   469 ERVKEDSDEQIKqledalkDVQKRMYESEgKVKQMQTHFlaLKEHLTNEAATGSHRVIEelREQLKDMKgKYEGASAEvg 548
Cdd:pfam15921   77 ERVLEEYSHQVK-------DLQRRLNESN-ELHEKQKFY--LRQSVIDLQTKLQEMQME--RDAMADIR-RRESQSQE-- 141

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   549 KLRNQIKQSEMLVEGFKRDESRLVEEnkrlqkecSTCEIDRERrgRRVTELEGQLKELGAKLA-------------LSVP 615
Cdd:pfam15921  142 DLRNQLQNTVHELEAAKCLKEDMLED--------SNTQIEQLR--KMMLSHEGVLQEIRSILVdfeeasgkkiyehDSMS 211

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   616 TETFESMKSSLSndisekaKRLAEVGRDYESSQGEIRQLKRDLESVRAQHIRPEE--HEQLRSRLEQKSGELGKKVTELT 693
Cdd:pfam15921  212 TMHFRSLGSAIS-------KILRELDTEISYLKGRIFPVEDQLEALKSESQNKIEllLQQHQDRIEQLISEHEVEITGLT 284

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   694 LKNQTLQKEVEKLYADNKLLNQQVHSLTV-------EMKTRYVPLRVS-EEMKKAHDVNVEDLNKKLSDATQRYAEKKLE 765
Cdd:pfam15921  285 EKASSARSQANSIQSQLEIIQEQARNQNSmymrqlsDLESTVSQLRSElREAKRMYEDKIEELEKQLVLANSELTEARTE 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   766 AERLLAENDKLTKNVSRLEAVFvapEKHEKEL--------------MGLKSNIAELKMQLCELNKKCGEGQEKIRALMSE 831
Cdd:pfam15921  365 RDQFSQESGNLDDQLQKLLADL---HKREKELslekeqnkrlwdrdTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSE 441

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   832 ntslkktlssqyvpaktheevkasLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLEnvqnQMKADYVSLEE 911
Cdd:pfam15921  442 ------------------------CQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVE----ELTAKKMTLES 493

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   912 HSRKMNMANQSLKEAQDAHTALLAdyrqgqeEIVTLHAEIKAQKKELDTiqeciklkyapLSRMEECERKFKATEKALKE 991
Cdd:pfam15921  494 SERTVSDLTASLQEKERAIEATNA-------EITKLRSRVDLKLQELQH-----------LKNEGDHLRNVQTECEALKL 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   992 QLSEQTHKGQVRDEEVKKGKQ---ENER----LRKDLAALQKELKDRNVLVEEAreaeRALSRKTEelgKQLKELSQKYS 1064
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQlvgQHGRtagaMQVEKAQLEKEINDRRLELQEF----KILKDKKD---AKIRELEARVS 628

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1065 DVKSEREKLVEEKAKQtseILAAQNLLQKQPVPLEQVEALKTSLNGTIEH---LKEELRSKERCLE--------REQQAV 1133
Cdd:pfam15921  629 DLELEKVKLVNAGSER---LRAVKDIKQERDQLLNEVKTSRNELNSLSEDyevLKRNFRNKSEEMEtttnklkmQLKSAQ 705

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1134 SQLQQLLENQKSSSVTLADHLQLKEALEKEVgimkASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKY 1213
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQI----TAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTV 781

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1214 KATKND-------LETQISNLNDKLASLNRKYDQVCEEKVSAKD-----EKELLHLNIEQEIrDQKERCDKSLTTIMELQ 1281
Cdd:pfam15921  782 ATEKNKmagelevLRSQERRLKEKVANMEVALDKASLQFAECQDiiqrqEQESVRLKLQHTL-DVKELQGPGYTSNSSMK 860

                          890
                   ....*....|....*
gi 564364067  1282 QRIQESAKQIEAKDN 1296
Cdd:pfam15921  861 PRLLQPASFTRTHSN 875
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 758-1356 2.44e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.54  E-value: 2.44e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   758 RYAEKKLEAERLLAENDKltkNVSRLEAVfvapekhekelmglksnIAELKMQLCELNKKcGEGQEKIRALMSENTSLKK 837
Cdd:TIGR02168  169 KYKERRKETERKLERTRE---NLDRLEDI-----------------LNELERQLKSLERQ-AEKAERYKELKAELRELEL 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   838 TLSS-QYVPAKTH----EEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEH 912
Cdd:TIGR02168  228 ALLVlRLEELREEleelQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQIL 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   913 SRKMNMANQSLKEAQdahtallADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQ 992
Cdd:TIGR02168  308 RERLANLERQLEELE-------AQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   993 LSEQthKGQVRDEEVKKGKQENE--RLRKDLAALQKElkdRNVLVEEAREAERALSR-KTEELGKQLKELSQKYSDVKSE 1069
Cdd:TIGR02168  381 LETL--RSKVAQLELQIASLNNEieRLEARLERLEDR---RERLQQEIEELLKKLEEaELKELQAELEELEEELEELQEE 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1070 REKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRS-KERCLEREQQA--VSQLQQLLEN---- 1142
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGvKALLKNQSGLSgiLGVLSELISVdegy 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1143 QKSSSVTLADHLQL-----KEALEKEVGIMKASLREKE---EESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYK 1214
Cdd:TIGR02168  536 EAAIEAALGGRLQAvvvenLNAAKKAIAFLKQNELGRVtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1215 ATKNDL------ETQISNLNDKLASLNRKYDQVCE--EKVSAK-------DEKELLHLNIEQEIRDQKERCDkslttimE 1279
Cdd:TIGR02168  616 KALSYLlggvlvVDDLDNALELAKKLRPGYRIVTLdgDLVRPGgvitggsAKTNSSILERRREIEELEEKIE-------E 688

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564364067  1280 LQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQSQLVDTLQQRVRDLQQQLADADRQHQE 1356
Cdd:TIGR02168  689 LEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEE 765
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 767-1317 8.28e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 67.07  E-value: 8.28e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   767 ERLLAENDKLTKNVSRleAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKcGEGQEKIRALMSEntslkktlssqyvpa 846
Cdd:pfam15921   77 ERVLEEYSHQVKDLQR--RLNESNELHEKQKFYLRQSVIDLQTKLQEMQME-RDAMADIRRRESQ--------------- 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   847 kTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREenevLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEA 926
Cdd:pfam15921  139 -SQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRK----MMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTM 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   927 --QDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPL-----SRMEECERKFKATEKALKEQLSE---Q 996
Cdd:pfam15921  214 hfRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLlqqhqDRIEQLISEHEVEITGLTEKASSarsQ 293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   997 THKGQVRDEEVK-KGKQENERLRKDLAALQKELKDrnvLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVE 1075
Cdd:pfam15921  294 ANSIQSQLEIIQeQARNQNSMYMRQLSDLESTVSQ---LRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQ 370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1076 EKAK---QTSEILAAQNLLQKQ-PVPLEQVEALKTSLNG---TIEHLKEELRS---------------KERC---LEREQ 1130
Cdd:pfam15921  371 ESGNlddQLQKLLADLHKREKElSLEKEQNKRLWDRDTGnsiTIDHLRRELDDrnmevqrleallkamKSECqgqMERQM 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1131 QA----------VSQLQQLLENQKSSSVTLADHLQLK----EALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTK 1196
Cdd:pfam15921  451 AAiqgkneslekVSSLTAQLESTKEMLRKVVEELTAKkmtlESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKL 530

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1197 QALKNLETRE--------VVDMSKYKATKND-----LETQISNLNDKLASLNRKYDQVCEEKvsAKDEKELLHLNIE-QE 1262
Cdd:pfam15921  531 QELQHLKNEGdhlrnvqtECEALKLQMAEKDkvieiLRQQIENMTQLVGQHGRTAGAMQVEK--AQLEKEINDRRLElQE 608

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564364067  1263 IRDQKercDKSLTTIMELQQRIQ----ESAKQIEAKDNKI----------TELLNDVERLKQALNGLSQ 1317
Cdd:pfam15921  609 FKILK---DKKDAKIRELEARVSdlelEKVKLVNAGSERLravkdikqerDQLLNEVKTSRNELNSLSE 674
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 476-1279 1.41e-10

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 65.81  E-value: 1.41e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   476 DEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNeaatgSHRVIEELREQLKDMKgkyegasaevgklrNQIK 555
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINN-----SNNKIKILEQQIKDLN--------------DKLK 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   556 QSEMLVEGFKRDESRLVEE--NKRLQKECSTCEIDRerrgrrvteLEGQLKELGAKLALsVPTETFEsmKSSLSNDISEK 633
Cdd:TIGR04523   93 KNKDKINKLNSDLSKINSEikNDKEQKNKLEVELNK---------LEKQKKENKKNIDK-FLTEIKK--KEKELEKLNNK 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   634 AKRLAEVGRDYESSQ----GEIRQLKRDLESVRAQHIRPEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLyad 709
Cdd:TIGR04523  161 YNDLKKQKEELENELnlleKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKK--- 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   710 NKLLNQQVhsltvemktryvplrvsEEMKKAHDvNVEDLNKKLSDATQRYAEKKLEAERLLAENDKLTKNVSRLEAVFVA 789
Cdd:TIGR04523  238 QQEINEKT-----------------TEISNTQT-QLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISD 299

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   790 --PEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLssqyvpaktheevkaslsSTLEKTNRAL 867
Cdd:TIGR04523  300 lnNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKEL------------------TNSESENSEK 361

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   868 ldsKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQdahtallADYRQGQEEIVTL 947
Cdd:TIGR04523  362 ---QRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQ-------QEKELLEKEIERL 431

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   948 HAEIKAQKKELDTIQECIKLKyaplsrmEECERKFKATEKALKEQLSEQThkgqvrdEEVKKGKQENERLRKDLAALQKE 1027
Cdd:TIGR04523  432 KETIIKNNSEIKDLTNQDSVK-------ELIIKNLDNTRESLETQLKVLS-------RSINKIKQNLEQKQKELKSKEKE 497

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1028 LKdrnvlveeareaerALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPL--EQVEALK 1105
Cdd:TIGR04523  498 LK--------------KLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELkkENLEKEI 563

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1106 TSLNGTIEHLKEELRSkercLEREQqavSQLQQLLENQKSSSVTLADHLQLKEA----LEKEVGIMKASLREKEEESQKK 1181
Cdd:TIGR04523  564 DEKNKEIEELKQTQKS----LKKKQ---EEKQELIDQKEKEKKDLIKEIEEKEKkissLEKELEKAKKENEKLSSIIKNI 636

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1182 TKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKELL--HLNI 1259
Cdd:TIGR04523  637 KSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELSLHYKKYITRMIRIKDLPKLEekYKEI 716

                          810       820
                   ....*....|....*....|
gi 564364067  1260 EQEIRDQKErCDKSLTTIME 1279
Cdd:TIGR04523  717 EKELKKLDE-FSKELENIIK 735
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 33-216 1.54e-10

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 65.01  E-value: 1.54e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   33 DVEKVSsILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGI---DVATRDsaGRNALHLAAKYGHALCLQKLLQ 109
Cdd:PHA02875   47 DSEAIK-LLMKHGAIPDVKYPDIESELHDAVEEGDVKAVEELLDLGKfadDVFYKD--GMTPLHLATILKKLDIMKLLIA 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  110 YNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRT 189
Cdd:PHA02875  124 RGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACLDIEDCCGCTPLIIAMAKGDIAICKMLLDSGANIDYFGKNGCV 203

                         170       180
                  ....*....|....*....|....*...
gi 564364067  190 ALM-LGCEYGCRDAVEVLVRNGADLTLL 216
Cdd:PHA02875  204 AALcYAIENNKIDIVRLFIKRGADCNIM 231
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 24-239 1.93e-10

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 65.47  E-value: 1.93e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   24 RLMKAAERGDVEKVSSILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVA--------------------- 82
Cdd:PHA02876  147 KLIKERIQQDELLIAEMLLEGGADVNAKDIYCITPIHYAAERGNAKMVNLLLSYGADVNiialddlsvlecavdsknidt 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   83 ------TRDSAGRNALHLAAKYGHALCLQKLLQYNC--PTEHVDLQGRTALHDAAMAdcPSSIQL---LCDHGASVNAKD 151
Cdd:PHA02876  227 ikaiidNRSNINKNDLSLLKAIRNEDLETSLLLYDAgfSVNSIDDCKNTPLHHASQA--PSLSRLvpkLLERGADVNAKN 304

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  152 IDGRTPLVLATQMCRPTI-CQLLIDRGADVNSRDKQNRTALMLGCEYG-CRDAVEVLVRNGADLTLLDALGHDSSYYARI 229
Cdd:PHA02876  305 IKGETPLYLMAKNGYDTEnIRTLIMLGADVNAADRLYITPLHQASTLDrNKDIVITLLELGANVNARDYCDKTPIHYAAV 384

                         250
                  ....*....|
gi 564364067  230 GDNLDILNLL 239
Cdd:PHA02876  385 RNNVVIINTL 394
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 906-1365 2.27e-10

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 65.13  E-value: 2.27e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   906 YVSLEEHSRKMNMANQSLK-EAQDAHTALLADYRQGQEEIVTLHAEIKaqkKELDTIQECIKLKYAPLSRMEECERKFKA 984
Cdd:pfam05483  185 YMDLNNNIEKMILAFEELRvQAENARLEMHFKLKEDHEKIQHLEEEYK---KEINDKEKQVSLLLIQITEKENKMKDLTF 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   985 TEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDL----AALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELS 1060
Cdd:pfam05483  262 LLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELedikMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELN 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1061 QKYSD------------------VKSEREKLveEKAKQTSEILAAQnlLQKQPVPLEQVEALKTSLNGTIEHLKEELRSK 1122
Cdd:pfam05483  342 KAKAAhsfvvtefeattcsleelLRTEQQRL--EKNEDQLKIITME--LQKKSSELEEMTKFKNNKEVELEELKKILAED 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1123 ERCLEREQQavsqLQQLLENQKSSSVTLADHLQLKEaleKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKqaLKNL 1202
Cdd:pfam05483  418 EKLLDEKKQ----FEKIAEELKGKEQELIFLLQARE---KEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEK--LKNI 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1203 ETREVVDMSKYKATKNDLETQ------------ISNLNDKLASLNRKYDQVCEEKVSAKDEKELLHLNIEQEIRDQKERC 1270
Cdd:pfam05483  489 ELTAHCDKLLLENKELTQEASdmtlelkkhqedIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKL 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1271 DKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQSQLVDTLQQRVRDLQQQLADA 1350
Cdd:pfam05483  569 DKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASA 648

                          490
                   ....*....|....*
gi 564364067  1351 DRQHQEVIAIYRTHL 1365
Cdd:pfam05483  649 KQKFEEIIDNYQKEI 663
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
861-1350 2.63e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.06  E-value: 2.63e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  861 EKTNRALLDSKKRLDDTSQEFSKLREE-NEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADYRQ 939
Cdd:PRK02224  169 ERASDARLGVERVLSDQRGSLDQLKAQiEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEE 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  940 GQEEIVTLHAEIKaqkKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQLSEqthkGQVRDEEVKKGKQENERLRK 1019
Cdd:PRK02224  249 RREELETLEAEIE---DLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAE----AGLDDADAEAVEARREELED 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1020 DLAALQKELKDRNVLVEEAR-EAERA------LSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQ 1092
Cdd:PRK02224  322 RDEELRDRLEECRVAAQAHNeEAESLredaddLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG 401

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1093 KQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQK----------SSSV-TLADHLQLKEALE 1161
Cdd:PRK02224  402 DAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegSPHVeTIEEDRERVEELE 481

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1162 KEVgimkASLREKEEESQKK---TKEVSKLQTEVQNTKQALKNLETRevvdmskykatkndletqisnLNDKLASLNRKY 1238
Cdd:PRK02224  482 AEL----EDLEEEVEEVEERlerAEDLVEAEDRIERLEERREDLEEL---------------------IAERRETIEEKR 536

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1239 DQvCEEKVSAKDEKELLHLNIEQEIRDQKERCDKSLTTIMELQQRIQESAKQIEAKDN------KITELLNDVERLKQAL 1312
Cdd:PRK02224  537 ER-AEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERirtllaAIADAEDEIERLREKR 615

                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 564364067 1313 NGLSQLTyssggpTKRQSQLvDTLQQRVRDLQQQLADA 1350
Cdd:PRK02224  616 EALAELN------DERRERL-AEKRERKRELEAEFDEA 646
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 67-227 2.70e-10

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 64.21  E-value: 2.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   67 NLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGAS 146
Cdd:PHA02874  103 EKDMIKTILDCGIDVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKLLLEKGAY 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  147 VNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGcRDAVEVLVrNGADLTLLDALGHDSSYY 226
Cdd:PHA02874  183 ANVKDNNGESPLHNAAEYGDYACIKLLIDHGNHIMNKCKNGFTPLHNAIIHN-RSAIELLI-NNASINDQDIDGSTPLHH 260


                  .
gi 564364067  227 A 227
Cdd:PHA02874  261 A 261
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 760-1348 5.08e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 5.08e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  760 AEKKLEA--ERLLAENDK---LTKNVSRLE--------AVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIR 826
Cdd:COG1196   177 AERKLEAteENLERLEDIlgeLERQLEPLErqaekaerYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELE 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  827 ALMSENTSLKKTLssqyvpaktheevkASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADY 906
Cdd:COG1196   257 ELEAELAELEAEL--------------EELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  907 VSLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQEciklkyaplsRMEECERKFKATE 986
Cdd:COG1196   323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE----------ELEELAEELLEAL 392

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  987 KALKEQLSEQTHKGQV---RDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKY 1063
Cdd:COG1196   393 RAAAELAAQLEELEEAeeaLLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1064 SDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQV-EALKTSLNGTIEHLKEELRSKERCLE--------------- 1127
Cdd:COG1196   473 ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVkAALLLAGLRGLAGAVAVLIGVEAAYEaaleaalaaalqniv 552

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1128 -REQQAVSQLQQLLENQKSSSVT-----LADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKN 1201
Cdd:COG1196   553 vEDDEVAAAAIEYLKAAKAGRATflpldKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1202 LETREVVDMSKYKATKNDLETQISNLNDKLASLNRKydQVCEEKVSAKDEKELLHLNIEQEIRDQKERCDKSLTTIMELQ 1281
Cdd:COG1196   633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRR--ELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA 710

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564364067 1282 QRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQSQLVDTLQQRVRDLQQQLA 1348
Cdd:COG1196   711 EAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIE 777
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 476-1079 1.24e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.03  E-value: 1.24e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  476 DEQIKQLE-DALKDVQKRMYESEGKVKQMQTHFLALKEHLTNEAATgsHRVIEELREQLKDMKGKYEGASAEVGKLRNQI 554
Cdd:COG1196   199 ERQLEPLErQAEKAERYRELKEELKELEAELLLLKLRELEAELEEL--EAELEELEAELEELEAELAELEAELEELRLEL 276

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  555 KQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVTELEGQLKELGAKLALSvptetfESMKSSLSNDISEKA 634
Cdd:COG1196   277 EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL------EEELEELEEELEEAE 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  635 KRLAEVGRDYESSQGEIRQLKRDLESVRAQHirpEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLYADNKLLN 714
Cdd:COG1196   351 EELEEAEAELAEAEEALLEAEAELAEAEEEL---EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE 427

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  715 QQVHSLTVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLAENDKLtknVSRLEAVFVAPEKHE 794
Cdd:COG1196   428 EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA---AARLLLLLEAEADYE 504

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  795 KELMGLKSniAELKMQLCELNKKCGE-------------------GQEKIRALMSENTSLKKTLSSQ------YVPAKTH 849
Cdd:COG1196   505 GFLEGVKA--ALLLAGLRGLAGAVAVligveaayeaaleaalaaaLQNIVVEDDEVAAAAIEYLKAAkagratFLPLDKI 582

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  850 EEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLR----RNLENVQNQMKADYVSLEEHSRKMNMANQSLKE 925
Cdd:COG1196   583 RARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtlvaARLEAALRRAVTLAGRLREVTLEGEGGSAGGSL 662

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  926 AQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQEciklkyaplsRMEECERKFKATEKALKEQLSEQTHKGQVRDE 1005
Cdd:COG1196   663 TGGSRRELLAALLEAEAELEELAERLAEEELELEEALL----------AEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1006 EVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGK-------QLKELSQKYSDVKSEREKLVEEKA 1078
Cdd:COG1196   733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPvnllaieEYEELEERYDFLSEQREDLEEARE 812


                  .
gi 564364067 1079 K 1079
Cdd:COG1196   813 T 813
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 527-1318 1.84e-09

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 62.76  E-value: 1.84e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   527 EELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEE-NKRLQKECSTCEIDRERRGRRVTELEGQLKE 605
Cdd:TIGR00606  244 ENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKmEKVFQGTDEQLNDLYHNHQRTVREKERELVD 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   606 LGAKLA-LSVPTETFESMKSSLSNDISE---KAKRLAEVGRDYES------SQGEIRQLKRDLESVRAQHirpEEHEQLR 675
Cdd:TIGR00606  324 CQRELEkLNKERRLLNQEKTELLVEQGRlqlQADRHQEHIRARDSliqslaTRLELDGFERGPFSERQIK---NFHTLVI 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   676 SRLEQKSGELGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRvseemkkahdvNVEDLNKKLSDA 755
Cdd:TIGR00606  401 ERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELK-----------FVIKELQQLEGS 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   756 TQRYAEKKLEAERLLAENDKLTKNVSrleavfvaPEKHEKELMGLKSNIAELKMQLCELNkkcgegqEKIRALMSENTSL 835
Cdd:TIGR00606  470 SDRILELDQELRKAERELSKAEKNSL--------TETLKKEVKSLQNEKADLDRKLRKLD-------QEMEQLNHHTTTR 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   836 KKTLSSQYVPAKTHEEVKASLSSTLEKTNRALLD--SKKRLDDTsqeFSKLREENEVLRRNLENVQNQMKadyvSLEEHS 913
Cdd:TIGR00606  535 TQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfpNKKQLEDW---LHSKSKEINQTRDRLAKLNKELA----SLEQNK 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   914 RKMNMANQSLKEAQDAHTALLADYRQGQEEIV---TLHAEIKAQKKELDTIQECIKLKYAPLSRMEE--------CERKF 982
Cdd:TIGR00606  608 NHINNELESKEEQLSSYEDKLFDVCGSQDEESdleRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDenqsccpvCQRVF 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   983 KaTEKALKEQLSEQTHKGQV-------RDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQ 1055
Cdd:TIGR00606  688 Q-TEAELQEFISDLQSKLRLapdklksTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKND 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1056 LKELSQKYSDVKSErEKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNG--TIEHLKEELRSKERCLEREQQAV 1133
Cdd:TIGR00606  767 IEEQETLLGTIMPE-EESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLdrTVQQVNQEKQEKQHELDTVVSKI 845

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1134 SQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTK-------QALKNLETRE 1206
Cdd:TIGR00606  846 ELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKeqdspleTFLEKDQQEK 925

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1207 VVDMSKYKATK-------NDLETQISNLNDKLASLNRKYDQVCEEKVSAKdEKELLHLNIE-QEIRDQKERCDKSLTTIM 1278
Cdd:TIGR00606  926 EELISSKETSNkkaqdkvNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQK-ETELNTVNAQlEECEKHQEKINEDMRLMR 1004

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 564364067  1279 EL--QQRIQESAKQIEAKDNKITELLNDVER-LKQALNGLSQL 1318
Cdd:TIGR00606 1005 QDidTQKIQERWLQDNLTLRKRENELKEVEEeLKQHLKEMGQM 1047
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
747-1315 5.35e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.82  E-value: 5.35e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  747 DLNKKLSDATQRYAEKKLEAERLLAENDKLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELkmqlcelnkkcgegQEKIR 826
Cdd:PRK02224  203 DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDL--------------RETIA 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  827 ALMSENTSLKKTLSSQyvpAKTHEEVKASLSSTLEKTNRALLDSkkrlDDTSQEFSKLREENEVLRRNLENVQnqmkady 906
Cdd:PRK02224  269 ETEREREELAEEVRDL---RERLEELEEERDDLLAEAGLDDADA----EAVEARREELEDRDEELRDRLEECR------- 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  907 VSLEEHSRKMnmanQSLKEAQDAHTALLADYRqgqEEIVTLHAEIKAQKKELDTIQEciklkyaplsRMEECERKFKATE 986
Cdd:PRK02224  335 VAAQAHNEEA----ESLREDADDLEERAEELR---EEAAELESELEEAREAVEDRRE----------EIEELEEEIEELR 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  987 KALkEQLSEQTHKGQVRDEEVkkgKQENERLRKDLAALQKELKDRNVLVEEAREAERAlsRKTEELGKQLKElsqkysdv 1066
Cdd:PRK02224  398 ERF-GDAPVDLGNAEDFLEEL---REERDELREREAELEATLRTARERVEEAEALLEA--GKCPECGQPVEG-------- 463

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1067 kSEREKLVEEKAKQTSEILAAqnllqkqpvpLEQVEALKTSLNGTIEHLkEELRSKERCLEREQQAVSQLQQLLENQKSS 1146
Cdd:PRK02224  464 -SPHVETIEEDRERVEELEAE----------LEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEELIAERRET 531

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1147 ----SVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDmskykATKNDLET 1222
Cdd:PRK02224  532 ieekRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLL-----AAIADAED 606

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1223 QISNLNDKLASLNRKYDQVcEEKVSAKDEKellHLNIEQEIRDQKercdkslttIMELQQRIQESAKQIEAKDNKITELL 1302
Cdd:PRK02224  607 EIERLREKREALAELNDER-RERLAEKRER---KRELEAEFDEAR---------IEEAREDKERAEEYLEQVEEKLDELR 673

                         570
                  ....*....|...
gi 564364067 1303 NDVERLKQALNGL 1315
Cdd:PRK02224  674 EERDDLQAEIGAV 686
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1039-1349 5.57e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 5.57e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1039 REAERALsRKTEELGKQLKELSQKYSDVKSEREKLVEEKAK--------------QTSEILAAQNLLQKQpvpLEQVEAL 1104
Cdd:TIGR02169  170 RKKEKAL-EELEEVEENIERLDLIIDEKRQQLERLRREREKaeryqallkekreyEGYELLKEKEALERQ---KEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1105 KTSLNGTIEHLKEELRSKERCLEREQQAVSQLqqlleNQKSSSVTLADHLQLKEALEK---EVGIMKASLREKEEESQKK 1181
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEEL-----NKKIKDLGEEEQLRVKEKIGEleaEIASLERSIAEKERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1182 TKEVSKLQTEVQNTKQALKNLETrevvDMSKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEkellHLNIEQ 1261
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELER----EIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE----LKDYRE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1262 EIRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQSQLVDTLQQRVR 1341
Cdd:TIGR02169  393 KLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELY 472


                   ....*...
gi 564364067  1342 DLQQQLAD 1349
Cdd:TIGR02169  473 DLKEEYDR 480
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 55-209 6.46e-09

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 59.89  E-value: 6.46e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   55 GRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHdAAMADCP 134
Cdd:PHA02878  168 GNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDARDKCGNTPLH-ISVGYCK 246

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564364067  135 SS--IQLLCDHGASVNAKD-IDGRTPLVLATQmcRPTICQLLIDRGADVNSRDKQNRTAL-MLGCEYGCRDAVEVLVRN 209
Cdd:PHA02878  247 DYdiLKLLLEHGVDVNAKSyILGLTALHSSIK--SERKLKLLLEYGADINSLNSYKLTPLsSAVKQYLCINIGRILISN 323
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 882-1206 7.83e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.46  E-value: 7.83e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   882 SKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHtALLADYRQGQEEIVTLhaEIKAQKKELDTI 961
Cdd:TIGR02168  168 SKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYK-ELKAELRELELALLVL--RLEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   962 QECIKlkyaplsRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREA 1041
Cdd:TIGR02168  245 QEELK-------EAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1042 ERALSRKTEELGKQLKELSQKYSDVKSE----REKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALK----------TS 1107
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKleelKEELESLEAELEELEAELEELESRLEELEEQLETLRskvaqlelqiAS 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1108 LNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQ--KSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEV 1185
Cdd:TIGR02168  398 LNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAelKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL 477

                          330       340
                   ....*....|....*....|.
gi 564364067  1186 SKLQTEVQNTKQALKNLETRE 1206
Cdd:TIGR02168  478 DAAERELAQLQARLDSLERLQ 498
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1029-1344 9.12e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.46  E-value: 9.12e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1029 KDRNVLVEEA----------REAERALSRKTE----------ELGKQLK------ELSQKYSDVKSEREKLveEKAKQTS 1082
Cdd:TIGR02168  155 EERRAIFEEAagiskykerrKETERKLERTREnldrledilnELERQLKslerqaEKAERYKELKAELREL--ELALLVL 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1083 EILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQ-LKEALE 1161
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQiLRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1162 ------KEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLN 1235
Cdd:TIGR02168  313 nlerqlEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1236 RKYDQVCEEKVSAKDEKELLHLNIEQEIRDQKERCDKSLTTIM-ELQQRIQESAKQIEAKDNKITELLNDVERLKQALNG 1314
Cdd:TIGR02168  393 LQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELkELQAELEELEEELEELQEELERLEEALEELREELEE 472

                          330       340       350
                   ....*....|....*....|....*....|
gi 564364067  1315 LSQLTYSSGGPTKRQSQLVDTLQQRVRDLQ 1344
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLE 502
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 430-786 9.43e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 9.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   430 KKELEAMRTFCDSAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEgKVKQMQTHFLA 509
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE-QLEERIAQLSK 754

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   510 LKEHLTNEaATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDR 589
Cdd:TIGR02168  755 ELTELEAE-IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   590 ERRGRRVTELEGQLKELgaklalsvpTETFESMKSSLSN---DISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQHi 666
Cdd:TIGR02168  834 AATERRLEDLEEQIEEL---------SEDIESLAAEIEEleeLIEELESELEALLNERASLEEALALLRSELEELSEEL- 903

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   667 rpEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLYAdnKLLNQqvHSLTVEMKTRYVPLRVSEEMKKAHDvnVE 746
Cdd:TIGR02168  904 --RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE--RLSEE--YSLTLEEAEALENKIEDDEEEARRR--LK 975

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*..
gi 564364067   747 DLNKKLS-------DATQRYAEKKLEAERLLAENDKLTKNVSRLEAV 786
Cdd:TIGR02168  976 RLENKIKelgpvnlAAIEEYEELKERYDFLTAQKEDLTEAKETLEEA 1022
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 137-234 1.33e-08

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 59.53  E-value: 1.33e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  137 IQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLTLL 216
Cdd:PTZ00322   98 ARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRHSQCHFEL 177

                          90
                  ....*....|....*...
gi 564364067  217 DALGHDSSYYARIGDNLD 234
Cdd:PTZ00322  178 GANAKPDSFTGKPPSLED 195
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 525-1203 1.51e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 1.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  525 VIEELREQLkdmkgkyegasaevgklrnqikqsemlvegfkrdesrlveenKRLQKECstceidreRRGRRVTELEGQLK 604
Cdd:COG1196   194 ILGELERQL------------------------------------------EPLERQA--------EKAERYRELKEELK 223

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  605 ELGAKLALsvptetfesmksslsndisekaKRLAEVGRDYESSQGEIRQLKRDLESVRAQHirpEEHEQLRSRLEQKSGE 684
Cdd:COG1196   224 ELEAELLL----------------------LKLRELEAELEELEAELEELEAELEELEAEL---AELEAELEELRLELEE 278

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  685 LGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKLSDATQRYAEKKL 764
Cdd:COG1196   279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  765 EAERLLAENDKLTKNVSRLEAVFvapEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYV 844
Cdd:COG1196   359 ELAEAEEALLEAEAELAEAEEEL---EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  845 PAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNL------ENVQNQMKADYVSLEEHSRKMNM 918
Cdd:COG1196   436 EEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELaeaaarLLLLLEAEADYEGFLEGVKAALL 515

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  919 ANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTI-QECIK-LKYAPLSRMEecerkFKATEKALKEQLSEQ 996
Cdd:COG1196   516 LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVaAAAIEyLKAAKAGRAT-----FLPLDKIRARAALAA 590

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  997 THKGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELsqkysDVKSEREKLVEE 1076
Cdd:COG1196   591 ALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEG-----EGGSAGGSLTGG 665

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1077 KAKQTSEILAAQNLLQKqpvplEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQL 1156
Cdd:COG1196   666 SRRELLAALLEAEAELE-----ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE 740

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*..
gi 564364067 1157 KEALEKEvgimkasLREKEEESQKKTKEVSKLQTEVQNTKQALKNLE 1203
Cdd:COG1196   741 LLEEEEL-------LEEEALEELPEPPDLEELERELERLEREIEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 320-889 3.58e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 58.61  E-value: 3.58e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  320 EEVMVADDLESEREKLKSLLAAKEKQHEESLRTIEALKNRFKyfesdhpgpgsyssnRKEDMLHKQGQMYTADSQCTSPG 399
Cdd:PTZ00121 1312 EEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAE---------------AAADEAEAAEEKAEAAEKKKEEA 1376

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  400 VPPHMQSRSmlRPLELSLPSQTSYSENEILKKELEAMRTFCDSAKQDRLKLQNELAHKVAECKALALECERVKE--DSDE 477
Cdd:PTZ00121 1377 KKKADAAKK--KAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEakKKAE 1454

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  478 QIKQLEDALKDVQKRMYESEGKVKQMQthflALKEHLTNEAATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQS 557
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKADEAKKKAEE----AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA 1530

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  558 EmlvEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVTElegqlkelgaklalsvptetfesmKSSLSNDISEKAKRL 637
Cdd:PTZ00121 1531 E---EAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEE------------------------AKKAEEDKNMALRKA 1583

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  638 AEVGRDYESSQGEIRQLKRDLESVRAQHIRPEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQK---EVEKLYADNKLLN 714
Cdd:PTZ00121 1584 EEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKkaeELKKAEEENKIKA 1663

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  715 QQVHSLTVEMKtryvplRVSEEMKKAhdvnvEDLNKKLSDATQRYAEKKLEAERLlaeNDKLTKNVSRLEAVFVAPEKHE 794
Cdd:PTZ00121 1664 AEEAKKAEEDK------KKAEEAKKA-----EEDEKKAAEALKKEAEEAKKAEEL---KKKEAEEKKKAEELKKAEEENK 1729

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  795 KELMGLKSNIAELKMQLCELNKKcgEGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKaslsstlEKTNRALLDSKKRL 874
Cdd:PTZ00121 1730 IKAEEAKKEAEEDKKKAEEAKKD--EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELD-------EEDEKRRMEVDKKI 1800

                         570
                  ....*....|....*
gi 564364067  875 DDTSQEFSKLREENE 889
Cdd:PTZ00121 1801 KDIFDNFANIIEGGK 1815
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1012-1248 3.61e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.47  E-value: 3.61e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1012 QENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLL 1091
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1092 QKQPVPLEQV--EALKTSLNGTIEHL--KEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLAdhlQLKEALEKEVGIM 1167
Cdd:COG4942   100 EAQKEELAELlrALYRLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA---ALRAELEAERAEL 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1168 KASLREKEEESQkktkevsKLQTEVQNTKQALKNLETREvvdmSKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVS 1247
Cdd:COG4942   177 EALLAELEEERA-------ALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245


                  .
gi 564364067 1248 A 1248
Cdd:COG4942   246 A 246
Ank_4 pfam13637
Ankyrin repeats (many copies);
55-108 4.07e-08

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 50.74  E-value: 4.07e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 564364067    55 GRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLL 108
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1005-1206 4.42e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.08  E-value: 4.42e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1005 EEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEI 1084
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1085 LAAQNLLQKQPV---PLEQVEALKTSLNGT-----------IEHLKEELRSKERCLEREQQAVSQLQQLLENQKSS-SVT 1149
Cdd:COG4942   100 EAQKEELAELLRalyRLGRQPPLALLLSPEdfldavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAElEAL 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 564364067 1150 LADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETRE 1206
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 517-1253 4.66e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.81  E-value: 4.66e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   517 EAATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQ---KECSTCEIDRERRG 593
Cdd:pfam05483   71 ENSEGLSRLYSKLYKEAEKIKKWKVSIEAELKQKENKLQENRKIIEAQRKAIQELQFENEKVSlklEEEIQENKDLIKEN 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   594 RRVTELEGQLKELGAKLALSVPTETFESMKS-----SLSNDISEKAKRLAEVGRDYESSQGEIR-QLKRDLESVraQHIR 667
Cdd:pfam05483  151 NATRHLCNLLKETCARSAEKTKKYEYEREETrqvymDLNNNIEKMILAFEELRVQAENARLEMHfKLKEDHEKI--QHLE 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   668 PEEHEQLRSRLEQ------KSGELGKKVTELTLKNQTLQKEVEKLYADNKL-------LNQQVHSLTVEMKTRYVPLRVS 734
Cdd:pfam05483  229 EEYKKEINDKEKQvsllliQITEKENKMKDLTFLLEESRDKANQLEEKTKLqdenlkeLIEKKDHLTKELEDIKMSLQRS 308

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   735 EEMKKAHDvnvEDLNKKLSDATQRYAEKKLEAERLLAENDKLTKNVSRLEAVFVAPEKHEK-ELMGLKSNIAELKMQLCE 813
Cdd:pfam05483  309 MSTQKALE---EDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRtEQQRLEKNEDQLKIITME 385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   814 LNKKCGEGQEKIRALMS---ENTSLKKTLSSQYV---PAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREE 887
Cdd:pfam05483  386 LQKKSSELEEMTKFKNNkevELEELKKILAEDEKlldEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTS 465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   888 NEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECikl 967
Cdd:pfam05483  466 EEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEK--- 542

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   968 KYAPLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSR 1047
Cdd:pfam05483  543 EMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKK 622

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1048 KTEELGKQLKELsqkysDVKSEREKLVEEKAKQTSEILAaqNLLQKQpvpLEQVEALKTSLNGTIEHLK----EELRSKE 1123
Cdd:pfam05483  623 KGSAENKQLNAY-----EIKVNKLELELASAKQKFEEII--DNYQKE---IEDKKISEEKLLEEVEKAKaiadEAVKLQK 692

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1124 RCLEREQQAVSQLQQLLENQKSSsvtladHLQLKEALEKEVGIMKAslREKEEESQKKTkevsklqtevqntkqalknle 1203
Cdd:pfam05483  693 EIDKRCQHKIAEMVALMEKHKHQ------YDKIIEERDSELGLYKN--KEQEQSSAKAA--------------------- 743

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 564364067  1204 trevvdmskykatkndLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKE 1253
Cdd:pfam05483  744 ----------------LEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAK 777
trp TIGR00870
transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ ...
 9-221 4.72e-08

transient-receptor-potential calcium channel protein; The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family (TC. 1.A.4)The TRP-CC family has also been called the store-operated calcium channel (SOC) family. The prototypical members include the Drosophila retinal proteinsTRP and TRPL (Montell and Rubin, 1989; Hardie and Minke, 1993). SOC members of the family mediate the entry of extracellular Ca2+ into cells in responseto depletion of intracellular Ca2+ stores (Clapham, 1996) and agonist stimulated production of inositol-1,4,5 trisphosphate (IP3). One member of the TRP-CCfamily, mammalian Htrp3, has been shown to form a tight complex with the IP3 receptor (TC #1.A.3.2.1). This interaction is apparently required for IP3 tostimulate Ca2+ release via Htrp3. The vanilloid receptor subtype 1 (VR1), which is the receptor for capsaicin (the ?hot? ingredient in chili peppers) and servesas a heat-activated ion channel in the pain pathway (Caterina et al., 1997), is also a member of this family. The stretch-inhibitable non-selective cation channel(SIC) is identical to the vanilloid receptor throughout all of its first 700 residues, but it exhibits a different sequence in its last 100 residues. VR1 and SICtransport monovalent cations as well as Ca2+. VR1 is about 10x more permeable to Ca2+ than to monovalent ions. Ca2+ overload probably causes cell deathafter chronic exposure to capsaicin. (McCleskey and Gold, 1999). [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273311 [Multi-domain]  Cd Length: 743  Bit Score: 57.78  E-value: 4.72e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067     9 ASNHSLSAEWNKYddrlMKAAERGDVEKVSsilaKKGVHPGKLDVE-----GRSAFHVVAAKGNLECLNAIL-THGIDVA 82
Cdd:TIGR00870    9 AEESPLSDEEKAF----LPAAERGDLASVY----RDLEEPKKLNINcpdrlGRSALFVAAIENENLELTELLlNLSCRGA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067    83 TrdsaGRNALHLAAKYGHA---LCLQKLLQ---YNCPTEHVDLQ-------GRTALHDAAMADCPSSIQLLCDHGASVNA 149
Cdd:TIGR00870   81 V----GDTLLHAISLEYVDaveAILLHLLAafrKSGPLELANDQytseftpGITALHLAAHRQNYEIVKLLLERGASVPA 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   150 K----------DID----GRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALML-------GCEY----------- 197
Cdd:TIGR00870  157 RacgdffvksqGVDsfyhGESPLNAAACLGSPSIVALLSEDPADILTADSLGNTLLHLlvmenefKAEYeelscqmynfa 236

                          250       260       270
                   ....*....|....*....|....*....|
gi 564364067   198 -----GCRDAVEV-LVRNGADLTLLDALGH 221
Cdd:TIGR00870  237 lslldKLRDSKELeVILNHQGLTPLKLAAK 266
Ank_4 pfam13637
Ankyrin repeats (many copies);
121-174 5.35e-08

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 50.35  E-value: 5.35e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 564364067   121 GRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLI 174
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
921-1383 8.60e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.70  E-value: 8.60e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  921 QSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLkYAPLSRMEECERKFKATEKALkEQLSEQTHKG 1000
Cdd:COG4717    81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL-LPLYQELEALEAELAELPERL-EELEERLEEL 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1001 QVRDEEVKKGKQENERLRKDLAALQKELKDRNVL-VEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAK 1079
Cdd:COG4717   159 RELEEELEELEAELAELQEELEELLEQLSLATEEeLQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEA 238

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1080 Q---------------TSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQK 1144
Cdd:COG4717   239 AaleerlkearlllliAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEE 318

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1145 SSSVTLADHLQLKEALEKEvgiMKASLREKEEESQKKTKEVSKLQTEVQntkqaLKNLETREVVDMSKYKAtkndletqi 1224
Cdd:COG4717   319 EELEELLAALGLPPDLSPE---ELLELLDRIEELQELLREAEELEEELQ-----LEELEQEIAALLAEAGV--------- 381

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1225 snlnDKLASLNRKYDQVcEEKVSAKDEKELLHLNIEQEIRDQKERCDKSLTTimELQQRIQESAKQIEAKDNKITELLND 1304
Cdd:COG4717   382 ----EDEEELRAALEQA-EEYQELKEELEELEEQLEELLGELEELLEALDEE--ELEEELEELEEELEELEEELEELREE 454

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564364067 1305 VERLKQALNGLsqltyssggptkRQSQLVDTLQQRVRDLQQQLADADRQHQEVIAIYrtHLLSAAQGHMDEDVQAALLQ 1383
Cdd:COG4717   455 LAELEAELEQL------------EEDGELAELLQELEELKAELRELAEEWAALKLAL--ELLEEAREEYREERLPPVLE 519
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 432-1059 1.37e-07

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 56.34  E-value: 1.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   432 ELEAMRTFCDSAKQDRLKLQNELAHKVAE----CKALALECERVKE---DSDEQIKQLEDALKDVQKRMYESEGKVKQMQ 504
Cdd:pfam01576   58 EAEEMRARLAARKQELEEILHELESRLEEeeerSQQLQNEKKKMQQhiqDLEEQLDEEEAARQKLQLEKVTTEAKIKKLE 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   505 THFLALKEHltNEAATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNqiKQSEMLVEgfkrDESRLVEENKRLQKecst 584
Cdd:pfam01576  138 EDILLLEDQ--NSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKN--KHEAMISD----LEERLKKEEKGRQE---- 205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   585 CEIDRERRGRRVTELEGQLKELGAKLA-LSVPTETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRA 663
Cdd:pfam01576  206 LEKAKRKLEGESTDLQEQIAELQAQIAeLRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERA 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   664 QHIRPEEH-------------------------EQLRSRLEQKSGELGKKVTELTLKNQT---------------LQKEV 703
Cdd:pfam01576  286 ARNKAEKQrrdlgeelealkteledtldttaaqQELRSKREQEVTELKKALEEETRSHEAqlqemrqkhtqaleeLTEQL 365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   704 EKLYADNKLLNQQVHSLTVEMKTRYVPLRV-------SEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLAENDKL 776
Cdd:pfam01576  366 EQAKRNKANLEKAKQALESENAELQAELRTlqqakqdSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESV 445

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   777 TKNVSRLEAVFVapeKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQyvpakthEEVKASL 856
Cdd:pfam01576  446 SSLLNEAEGKNI---KLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEE-------EEAKRNV 515

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   857 SSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMK---ADYVSLEEHSRKMNMANQSLKEAQDAHTAL 933
Cdd:pfam01576  516 ERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEekaAAYDKLEKTKNRLQQELDDLLVDLDHQRQL 595

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   934 LADYRQGQEEIVTLHAEIKAqkkeldtiqecIKLKYAPLSRMEECERKFKATeKALkeQLSEQTHKGQVRDEEVKKgkqE 1013
Cdd:pfam01576  596 VSNLEKKQKKFDQMLAEEKA-----------ISARYAEERDRAEAEAREKET-RAL--SLARALEEALEAKEELER---T 658

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*.
gi 564364067  1014 NERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKEL 1059
Cdd:pfam01576  659 NKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEEL 704
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 427-706 2.43e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.45  E-value: 2.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   427 EILKKELEAMRTFCDSAKQDRLKLQNE---LAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQM 503
Cdd:TIGR02168  736 ARLEAEVEQLEERIAQLSKELTELEAEieeLEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   504 QTHFLALKEHLTNEAATGS--HRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKE 581
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAatERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE 895

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   582 CSTCEIDRERRGRRVTELEGQLKELGAKLAlsvpteTFESMKSSLSNDISEKAKRLAEVGRD--------YESSQGEIRQ 653
Cdd:TIGR02168  896 LEELSEELRELESKRSELRRELEELREKLA------QLELRLEGLEVRIDNLQERLSEEYSLtleeaealENKIEDDEEE 969

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564364067   654 LKRDLESVRAQHIR--------PEEHEQLRSRLEqksgELGKKVTELTLKNQTLQKEVEKL 706
Cdd:TIGR02168  970 ARRRLKRLENKIKElgpvnlaaIEEYEELKERYD----FLTAQKEDLTEAKETLEEAIEEI 1026
PHA02875 PHA02875
ankyrin repeat protein; Provisional
 68-239 5.06e-07

ankyrin repeat protein; Provisional


Pssm-ID: 165206 [Multi-domain]  Cd Length: 413  Bit Score: 53.84  E-value: 5.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   68 LECLNAILTHGIDVATR--DSA---------GRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSS 136
Cdd:PHA02875    4 VALCDAILFGELDIARRllDIGinpnfeiydGISPIKLAMKFRDSEAIKLLMKHGAIPDVKYPDIESELHDAVEEGDVKA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  137 IQLLCDHGASVNakDI---DGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADL 213
Cdd:PHA02875   84 VEELLDLGKFAD--DVfykDGMTPLHLATILKKLDIMKLLIARGADPDIPNTDKFSPLHLAVMMGDIKGIELLIDHKACL 161

                         170       180
                  ....*....|....*....|....*.
gi 564364067  214 TLLDALGHDSSYYARIGDNLDILNLL 239
Cdd:PHA02875  162 DIEDCCGCTPLIIAMAKGDIAICKML 187
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
628-1210 5.41e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 54.28  E-value: 5.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  628 NDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRaqhirpEEHEQLRSRLEqksgELGKKVTELTLKNQTLQKEVEKLY 707
Cdd:PRK02224  209 NGLESELAELDEEIERYEEQREQARETRDEADEVL------EEHEERREELE----TLEAEIEDLRETIAETEREREELA 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  708 ADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLAENDKLTKNVSRLEAvf 787
Cdd:PRK02224  279 EEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEE-- 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  788 VAPEKHEKElmglksniAELKMQLCELNKKCGEGQEKIRALMSENTSLKKtlssqyvpaktheevkaslssTLEKTNRAL 867
Cdd:PRK02224  357 RAEELREEA--------AELESELEEAREAVEDRREEIEELEEEIEELRE---------------------RFGDAPVDL 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  868 LDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHsrKMNMANQSLKEAQDAHTalLADYRQGQEEIVTL 947
Cdd:PRK02224  408 GNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAG--KCPECGQPVEGSPHVET--IEEDRERVEELEAE 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  948 HAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEqlseqthkgqvRDEEVKKGKQENERLRKDLAALQKE 1027
Cdd:PRK02224  484 LEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAE-----------RRETIEEKRERAEELRERAAELEAE 552

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1028 lkdrnvlVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLveekaKQTSEILAAQNLLQKQPVPL-EQVEALKT 1106
Cdd:PRK02224  553 -------AEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL-----ERIRTLLAAIADAEDEIERLrEKREALAE 620

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1107 SLNGTIEHLKeELRSKERCLERE--QQAVSQLQQLLENQKSSSVTLADHLQLKEA----LEKEVGIMKASLREKEEESQK 1180
Cdd:PRK02224  621 LNDERRERLA-EKRERKRELEAEfdEARIEEAREDKERAEEYLEQVEEKLDELREerddLQAEIGAVENELEELEELRER 699

                         570       580       590
                  ....*....|....*....|....*....|..
gi 564364067 1181 KtkevsklqTEVQNTKQALKNL--ETREVVDM 1210
Cdd:PRK02224  700 R--------EALENRVEALEALydEAEELESM 723
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 942-1356 6.60e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.87  E-value: 6.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   942 EEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQLSEQTHK-------GQVRDEEVKKGKQEN 1014
Cdd:TIGR04523   40 KKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKinklnsdLSKINSEIKNDKEQK 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1015 ERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQ 1094
Cdd:TIGR04523  120 NKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKL 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1095 PVPLEQVEALK---TSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSssvtladhlQLKEALEKEVGImKASL 1171
Cdd:TIGR04523  200 ELLLSNLKKKIqknKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQT---------QLNQLKDEQNKI-KKQL 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1172 REKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKY--------KATKNDLETQISNLNDKLASLNRKYDQVce 1243
Cdd:TIGR04523  270 SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKElkselknqEKKLEEIQNQISQNNKIISQLNEQISQL-- 347

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1244 ekvsakdEKELLHLNIEQEirdqkercdkslttimELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQltyssg 1323
Cdd:TIGR04523  348 -------KKELTNSESENS----------------EKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLES------ 398

                          410       420       430
                   ....*....|....*....|....*....|...
gi 564364067  1324 gPTKRQSQLVDTLQQRVRDLQQQLADADRQHQE 1356
Cdd:TIGR04523  399 -KIQNQEKLNQQKDEQIKKLQQEKELLEKEIER 430
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 866-1087 7.96e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 7.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  866 ALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIV 945
Cdd:COG4942    14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  946 TLHAEIKAQKKELDTI---------QECIKLKYAP-----LSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGK 1011
Cdd:COG4942    94 ELRAELEAQKEELAELlralyrlgrQPPLALLLSPedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564364067 1012 QENERLRKDLAALQKELKDrnvLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAA 1087
Cdd:COG4942   174 AELEALLAELEEERAALEA---LKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 949-1141 8.53e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 8.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  949 AEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKEL 1028
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1029 KD-RNVLVEEAREAER-----------------ALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNL 1090
Cdd:COG4942   100 EAqKEELAELLRALYRlgrqpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 564364067 1091 LQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLE 1141
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 650-1310 8.92e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.82  E-value: 8.92e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   650 EIRQLKRDLESVRAQHIRPEEHEQLRSRLEQKSGELGKKVTELTLKNQtlqkevEKLYADNKLLNQQVHSLTVEMKTRYV 729
Cdd:pfam02463  184 NLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDY------LKLNEERIDLLQELLRDEQEEIESSK 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   730 PLRVSEEMKKAHDVNVEDLNK---KLSDATQRYAEKKLEAERLLAENDKLTKNVSRLEAVFV--APEKHEKELMGLKSNI 804
Cdd:pfam02463  258 QEIEKEEEKLAQVLKENKEEEkekKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESekEKKKAEKELKKEKEEI 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   805 AELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKL 884
Cdd:pfam02463  338 EELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   885 REENEVLRRNLENVQNQMKADYVSLEEHSRKmnmanqsLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQEC 964
Cdd:pfam02463  418 EDLLKEEKKEELEILEEEEESIELKQGKLTE-------EKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   965 IKLKYAPLSRMEECERKFKATEKALkeqlseqthkgqVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERA 1044
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLAL------------IKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1045 LSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAK-QTSEILAAQNLLQKQPVPLEQVEALKT-SLNGTIEHLKEELRSK 1122
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSiAVLEIDPILNLAQLDKATLEADEDDKRaKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1123 ERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKAS-----LREKEEESQKKTKEVSKLQTEVQNTKQ 1197
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAEselakEEILRRQLEIKKKEQREKEELKKLKLE 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1198 ALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKELLHLNIEQEIRDQKERCDKSLTTI 1277
Cdd:pfam02463  719 AEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKA 798

                          650       660       670
                   ....*....|....*....|....*....|...
gi 564364067  1278 MELQQRIQESAKQIEAKDNKITELLNDVERLKQ 1310
Cdd:pfam02463  799 QEEELRALEEELKEEAELLEEEQLLIEQEEKIK 831
TRPV5-6 cd22192
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...
 63-191 1.19e-06

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.


Pssm-ID: 411976 [Multi-domain]  Cd Length: 609  Bit Score: 53.09  E-value: 1.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   63 AAKGNLECLNAILT-HGIDVATRDSAGRNALHLAAKYGHALCLQKLLqyNCPTEHVDL-------QGRTALHDAAMADCP 134
Cdd:cd22192    25 AKENDVQAIKKLLKcPSCDLFQRGALGETALHVAALYDNLEAAVVLM--EAAPELVNEpmtsdlyQGETALHIAVVNQNL 102

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564364067  135 SSIQLLCDHGASVNA---------KDID-----GRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTAL 191
Cdd:cd22192   103 NLVRELIARGADVVSpratgtffrPGPKnliyyGEHPLSFAACVGNEEIVRLLIEHGADIRAQDSLGNTVL 173
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 746-1308 1.79e-06

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 52.91  E-value: 1.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  746 EDLNKKLSDAtqRYAEKKLEAERLLAENDKLTKNVSRLEAVFVAP-EKHEKELMGLKSNIAELKMQLCELNKKCG----E 820
Cdd:PTZ00440  943 EKIEKQLSDT--KINNLKMQIEKTLEYYDKSKENINGNDGTHLEKlDKEKDEWEHFKSEIDKLNVNYNILNKKIDdlikK 1020

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  821 GQEKIRALM-SENTSLKKTLS---SQYVPAKthEEVKASLSStLEKTNrallDSKKRLDDTSQE-FSKLREENEVLRRNL 895
Cdd:PTZ00440 1021 QHDDIIELIdKLIKEKGKEIEekvDQYISLL--EKMKTKLSS-FHFNI----DIKKYKNPKIKEeIKLLEEKVEALLKKI 1093

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  896 ENVQNQMKADYVSLEEHsrkMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQEC--IKLKYAPLS 973
Cdd:PTZ00440 1094 DENKNKLIEIKNKSHEH---VVNADKEKNKQTEHYNKKKKSLEKIYKQMEKTLKELENMNLEDITLNEVneIEIEYERIL 1170

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  974 RMEECErkfkatekalkeQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKElKDRNVLVEEAREAERALSRKTEELG 1053
Cdd:PTZ00440 1171 IDHIVE------------QINNEAKKSKTIMEEIESYKKDIDQVKKNMSKERND-HLTTFEYNAYYDKATASYENIEELT 1237

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1054 KQLKEL------SQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKqpvpLEQVEALKTSLNGTiEHLKEELRSKERCLE 1127
Cdd:PTZ00440 1238 TEAKGLkgeanrSTNVDELKEIKLQVFSYLQQVIKENNKMENALHE----IKNMYEFLISIDSE-KILKEILNSTKKAEE 1312

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1128 REQQAVSQLQqllenqKSSSVTLADHLQLKEALEKEvgiMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLetrev 1207
Cdd:PTZ00440 1313 FSNDAKKELE------KTDNLIKQVEAKIEQAKEHK---NKIYGSLEDKQIDDEIKKIEQIKEEISNKRKEINKY----- 1378

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1208 vdMSKYKATKNDLETQISNLN---DKLASLNRKydqvceEKVSAKDEKELlhlNIeQEIRDQKERCDKSLTTIMELQQRI 1284
Cdd:PTZ00440 1379 --LSNIKSNKEKCDLHVRNASrgkDKIDFLNKH------EAIEPSNSKEV---NI-IKITDNINKCKQYSNEAMETENKA 1446

                         570       580
                  ....*....|....*....|....
gi 564364067 1285 QESAKQIEAKDNKITELLNDVERL 1308
Cdd:PTZ00440 1447 DENNDSIIKYEKEITNILNNSSIL 1470
PHA02878 PHA02878
ankyrin repeat protein; Provisional
 137-239 2.00e-06

ankyrin repeat protein; Provisional


Pssm-ID: 222939 [Multi-domain]  Cd Length: 477  Bit Score: 52.19  E-value: 2.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  137 IQLLCDHGASVNAKDID-GRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLTL 215
Cdd:PHA02878  150 TKLLLSYGADINMKDRHkGNTALHYATENKDQRLTELLLSYGANVNIPDKTNNSPLHHAVKHYNKPIVHILLENGASTDA 229

                          90       100
                  ....*....|....*....|....*...
gi 564364067  216 LDALG----HDSSYYARigdNLDILNLL 239
Cdd:PHA02878  230 RDKCGntplHISVGYCK---DYDILKLL 254
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 669-1346 2.32e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 52.28  E-value: 2.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   669 EEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKeveklyadnkLLNQQVHSLTVEMKTRYVPLRVSEEMKKAHDVNVEDL 748
Cdd:TIGR00618  176 DQYTQLALMEFAKKKSLHGKAELLTLRSQLLTL----------CTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYL 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   749 NKKLSDATQRyAEKKLEAERLLAENDKLTKNVSRLEAvfvapEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRAL 828
Cdd:TIGR00618  246 TQKREAQEEQ-LKKQQLLKQLRARIEELRAQEAVLEE-----TQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSK 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   829 MSENTSLKktlssQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKAdyvs 908
Cdd:TIGR00618  320 MRSRAKLL-----MKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTT---- 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   909 LEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKA 988
Cdd:TIGR00618  391 LTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   989 LKEQLSEQthkgQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREA-------ERALSRKTEELGKQLKELSQ 1061
Cdd:TIGR00618  471 REQQLQTK----EQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDidnpgplTRRMQRGEQTYAQLETSEED 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1062 KYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLE 1141
Cdd:TIGR00618  547 VYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1142 NQKSSSV--TLADHLQLKEA---------LEKEVGIMKASLREKEEES-----------QKKTKEVSKLQTEVQNTKQAL 1199
Cdd:TIGR00618  627 LQDVRLHlqQCSQELALKLTalhalqltlTQERVREHALSIRVLPKELlasrqlalqkmQSEKEQLTYWKEMLAQCQTLL 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1200 KNLET------REVVDMSKYKAT-KNDLETQISNLNDKLASLNRKYDQVCEEKVSA---KDEKELLHL-------NIEQE 1262
Cdd:TIGR00618  707 RELEThieeydREFNEIENASSSlGSDLAAREDALNQSLKELMHQARTVLKARTEAhfnNNEEVTAALqtgaelsHLAAE 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1263 IRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLndVERLKQALNGLSQLTYSSGGPTKRQSQLVDTLQQRVRD 1342
Cdd:TIGR00618  787 IQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETL--VQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQL 864


                   ....
gi 564364067  1343 LQQQ 1346
Cdd:TIGR00618  865 TQEQ 868
PRK01156 PRK01156
chromosome segregation protein; Provisional
 855-1351 2.40e-06

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 52.21  E-value: 2.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  855 SLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLEN---VQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHT 931
Cdd:PRK01156  142 SLISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNidyLEEKLKSSNLELENIKKQIADDEKSHSITLKEIE 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  932 ALLADYRQGQEEIVTLHAEIKAQKKELDTI---QECIKLKYAPLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVK 1008
Cdd:PRK01156  222 RLSIEYNNAMDDYNNLKSALNELSSLEDMKnryESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYF 301

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1009 KGKQENERLRKDLAALQKELKDRNVLVEEAREAERALS------RKTEELGKQLKELSQKYSD-------VKSEREKLVE 1075
Cdd:PRK01156  302 KYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNdyikkkSRYDDLNNQILELEGYEMDynsylksIESLKKKIEE 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1076 EKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRS---KERCLEREQQAVSQLQQLLENQKSSSV---T 1149
Cdd:PRK01156  382 YSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSlnqRIRALRENLDELSRNMEMLNGQSVCPVcgtT 461

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1150 LADhlqlkEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLND 1229
Cdd:PRK01156  462 LGE-----EKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKI 536

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1230 KLASLNRKYDQVCEekvsAKDEKELLHLNIEQEIRDQ--KERCDKSLTTIMELQQRIQESAKQI---EAKDNKITELLND 1304
Cdd:PRK01156  537 KINELKDKHDKYEE----IKNRYKSLKLEDLDSKRTSwlNALAVISLIDIETNRSRSNEIKKQLndlESRLQEIEIGFPD 612

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 564364067 1305 VERLKQALNGLSQLTYSSGGPTKRQSQ----LVDTLQQRVRDLQQQLADAD 1351
Cdd:PRK01156  613 DKSYIDKSIREIENEANNLNNKYNEIQenkiLIEKLRGKIDNYKKQIAEID 663
PHA02798 PHA02798
ankyrin-like protein; Provisional
 137-245 2.87e-06

ankyrin-like protein; Provisional


Pssm-ID: 222931 [Multi-domain]  Cd Length: 489  Bit Score: 51.76  E-value: 2.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  137 IQLLCDHGASVNAKDIDGRTPL--VLATQMCRPT---ICQLLIDRGADVNSRDKQNRTAL--MLGCEY-GCRDAVEVLVR 208
Cdd:PHA02798   54 VKLFINLGANVNGLDNEYSTPLctILSNIKDYKHmldIVKILIENGADINKKNSDGETPLycLLSNGYiNNLEILLFMIE 133

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 564364067  209 NGADLTLLDALGHDS-SYYARIGDNLDIlNLLKTASES 245
Cdd:PHA02798  134 NGADTTLLDKDGFTMlQVYLQSNHHIDI-EIIKLLLEK 170
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 477-1240 4.20e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 51.59  E-value: 4.20e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   477 EQIKQLEDALKDVQKRMYESegKVKQMQTHFLALKEHLTNEAATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQ 556
Cdd:TIGR01612  974 DKINELDKAFKDASLNDYEA--KNNELIKYFNDLKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHT 1051

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   557 S-EMLVEGFKRDESRLVEE-NKRLQKECST--CEIDRERRGRRVTELEGQLKELGAKLALSVptETFESMKSSLSNDISE 632
Cdd:TIGR01612 1052 SiYNIIDEIEKEIGKNIELlNKEILEEAEIniTNFNEIKEKLKHYNFDDFGKEENIKYADEI--NKIKDDIKNLDQKIDH 1129

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   633 KAKRLAEVGRDYESSQGEIRQLKRDLESVRAQHIRPEEHEQLRSRLEQKSGELGKKVTELTLKNQTL---------QKEV 703
Cdd:TIGR01612 1130 HIKALEEIKKKSENYIDEIKAQINDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLneiaeiekdKTSL 1209

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   704 EKLYADNKLLNQQVHSLTVEMKTRyvPLRVSEEMKKAHDVNVEDLNkKLSDATQRYAEKKLEAERLLAENDKLTKNVSRL 783
Cdd:TIGR01612 1210 EEVKGINLSYGKNLGKLFLEKIDE--EKKKSEHMIKAMEAYIEDLD-EIKEKSPEIENEMGIEMDIKAEMETFNISHDDD 1286

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   784 EAVFVAPEKHEKELmglkSNIAELKMQLCELNKKcgegqekiralMSENTSLKKTLSSQYVPAKTH-EEVKASLSSTLEK 862
Cdd:TIGR01612 1287 KDHHIISKKHDENI----SDIREKSLKIIEDFSE-----------ESDINDIKKELQKNLLDAQKHnSDINLYLNEIANI 1351

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   863 TNRALLDSKKRLDDTSQEFS-KLREENEVLRRNLENVQNQMKA--DYVSLEEHSRKMnmanQSLKEAQDAHtALLADYRQ 939
Cdd:TIGR01612 1352 YNILKLNKIKKIIDEVKEYTkEIEENNKNIKDELDKSEKLIKKikDDINLEECKSKI----ESTLDDKDID-ECIKKIKE 1426

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   940 GQEEIVTLHAEIKAQKKELDTIQECIKLKYaplSRMEECERKfkaTEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRK 1019
Cdd:TIGR01612 1427 LKNHILSEESNIDTYFKNADENNENVLLLF---KNIEMADNK---SQHILKIKKDNATNDHDFNINELKEHIDKSKGCKD 1500

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1020 DLAALQKELKDRNVLVEEAREAERALSRKTEELgkqlkELSQKYSDVKSEREKLVEE-KAKQTSEILAAQNLLQKqpvpl 1098
Cdd:TIGR01612 1501 EADKNAKAIEKNKELFEQYKKDVTELLNKYSAL-----AIKNKFAKTKKDSEIIIKEiKDAHKKFILEAEKSEQK----- 1570

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1099 eqVEALKtslngtiehlKEELRSKERCL--EREQQAVSQLQQLLENQKSSSVTLA-------DHLQLKEALEKEVGIMka 1169
Cdd:TIGR01612 1571 --IKEIK----------KEKFRIEDDAAknDKSNKAAIDIQLSLENFENKFLKISdikkkinDCLKETESIEKKISSF-- 1636

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564364067  1170 SLREKEEESQKKTKEVSKLQTEVQNTKQALKNLEtrevvdmskykatknDLETQISNLNDKLASLNRKYDQ 1240
Cdd:TIGR01612 1637 SIDSQDTELKENGDNLNSLQEFLESLKDQKKNIE---------------DKKKELDELDSEIEKIEIDVDQ 1692
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
477-692 4.50e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 4.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  477 EQIKQLEDALKDVQK--RMYESEGKVKQMQTHFLALKEHLTNEAATgshRVIEELREQLKDMKGKYEGASAEVGKLRNQI 554
Cdd:COG4913   249 EQIELLEPIRELAERyaAARERLAELEYLRAALRLWFAQRRLELLE---AELEELRAELARLEAELERLEARLDALREEL 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  555 KQSEMLVEGFK-RDESRLVEENKRLQKEcstceidRERRGRRVTELEGQLKELGAKLALSvpTETFESMKS-------SL 626
Cdd:COG4913   326 DELEAQIRGNGgDRLEQLEREIERLERE-------LEERERRRARLEALLAALGLPLPAS--AEEFAALRAeaaalleAL 396

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564364067  627 SNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQHIR-PEEHEQLRSRLEQksgELGKKVTEL 692
Cdd:COG4913   397 EEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNiPARLLALRDALAE---ALGLDEAEL 460
46 PHA02562
endonuclease subunit; Provisional
 476-707 5.59e-06

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 50.78  E-value: 5.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  476 DEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNEAATgSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIK 555
Cdd:PHA02562  187 DMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKT-IKAEIEELTDELLNLVMDIEDPSAALNKLNTAAA 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  556 QSEMLVEGFKRDESrLVEENKrlqkECSTCEIDRERRGRRVTELEGQLKELGAKLALsvptetfesmkssLSNDISEKAK 635
Cdd:PHA02562  266 KIKSKIEQFQKVIK-MYEKGG----VCPTCTQQISEGPDRITKIKDKLKELQHSLEK-------------LDTAIDELEE 327

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564364067  636 RLAEVGRDYESSQG---EIRQLKRDLESVRAQHIRPE-EHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLY 707
Cdd:PHA02562  328 IMDEFNEQSKKLLElknKISTNKQSLITLVDKAKKVKaAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKY 403
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 940-1389 5.60e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 51.12  E-value: 5.60e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   940 GQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKE----------QLSEQTHKGQVRDEEVKK 1009
Cdd:TIGR00618  174 PLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEkelkhlrealQQTQQSHAYLTQKREAQE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1010 GKQENERLRKDLAALQKELKDRNVLVEEAREaERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQN 1089
Cdd:TIGR00618  254 EQLKKQQLLKQLRARIEELRAQEAVLEETQE-RINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAA 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1090 LLQKQPVPLEQVEALKTSLNG----TIEHLKEELRSKERCLER-EQQAVSQLQQLLENQKSSSVTLAdhlQLKEALEKEV 1164
Cdd:TIGR00618  333 HVKQQSSIEEQRRLLQTLHSQeihiRDAHEVATSIREISCQQHtLTQHIHTLQQQKTTLTQKLQSLC---KELDILQREQ 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1165 GIMKASLREKEEESQKKT----------KEVSKLQTEVQNTKQALKnLETREVVDMSKYKATKNDLETQISNLNDKLASL 1234
Cdd:TIGR00618  410 ATIDTRTSAFRDLQGQLAhakkqqelqqRYAELCAAAITCTAQCEK-LEKIHLQESAQSLKEREQQLQTKEQIHLQETRK 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1235 NRKYDQVCEEKVSAKD--EKELLHLNIEQEIRDQKE----RCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERL 1308
Cdd:TIGR00618  489 KAVVLARLLELQEEPCplCGSCIHPNPARQDIDNPGpltrRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEI 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1309 KQALNGLSQLTYSSggptkrqSQLVDTLQQRVRDLQQQLADADRQHQEVIAIYRTHLLSAAQGHMDEDVQAALLQIIQMR 1388
Cdd:TIGR00618  569 QQSFSILTQCDNRS-------KEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQEL 641


                   .
gi 564364067  1389 Q 1389
Cdd:TIGR00618  642 A 642
Ank_2 pfam12796
Ankyrin repeats (3 copies);
158-239 6.26e-06

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 45.88  E-value: 6.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   158 LVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGAdltlLDALGHDSS--YYARIGDNLDI 235
Cdd:pfam12796    1 LHLAAKNGNLELVKLLLENGADANLQDKNGRTALHLAAKNGHLEIVKLLLEHAD----VNLKDNGRTalHYAARSGHLEI 76


                   ....
gi 564364067   236 LNLL 239
Cdd:pfam12796   77 VKLL 80
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 942-1331 8.89e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.36  E-value: 8.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   942 EEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDL 1021
Cdd:pfam02463  160 EEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERI 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1022 AALQKELKDrnvlveeaREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLlqkqpvPLEQV 1101
Cdd:pfam02463  240 DLLQELLRD--------EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKS------ELLKL 305

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1102 EALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEvgimKASLREKEEESQKK 1181
Cdd:pfam02463  306 ERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEK----LEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1182 TKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKELLHLNIEQ 1261
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLL 461

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1262 EIRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQSQ 1331
Cdd:pfam02463  462 KDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRL 531
COG5022 COG5022
Myosin heavy chain [General function prediction only];
791-1318 9.66e-06

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 50.46  E-value: 9.66e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  791 EKHEKELMGLK---SNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKASLSSTLEKTNRA- 866
Cdd:COG5022   878 ELAERQLQELKidvKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELn 957

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  867 -LLDSKKRLDDTSQEFSKLREENEVLRRNL----ENVQNQMKA------DYVSLEEHS---RKMNMANQSLKEAQD---- 928
Cdd:COG5022   958 kLHEVESKLKETSEEYEDLLKKSTILVREGnkanSELKNFKKElaelskQYGALQESTkqlKELPVEVAELQSASKiiss 1037

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  929 AHTALLAdyRQGQEEIVTLH----AEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATE----KALKEQLSEQTHKG 1000
Cdd:COG5022  1038 ESTELSI--LKPLQKLKGLLllenNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINvkdlEVTNRNLVKPANVL 1115

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1001 QVRDEEVKK---GKQENERLRKDLAALQKELKDRNVLVE-----------EAREAERALSRKTEELGKQLKELSQKY--- 1063
Cdd:COG5022  1116 QFIVAQMIKlnlLQEISKFLSQLVNTLEPVFQKLSVLQLeldglfweanlEALPSPPPFAALSEKRLYQSALYDEKSkls 1195

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1064 -SDVKSEREKLVEEKAKQTSEILAA---QNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQL 1139
Cdd:COG5022  1196 sSEVNDLKNELIALFSKIFSGWPRGdklKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSY 1275

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1140 LENQKSSSVTLADHLQLKEALEKEVGIMKAS-----------LREKEEESQKKTKEVSKLQTEVQNTKQALKNLETRevv 1208
Cdd:COG5022  1276 KLEEEVLPATINSLLQYINVGLFNALRTKASslrwksatevnYNSEELDDWCREFEISDVDEELEELIQAVKVLQLL--- 1352

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1209 dmskykatKNDLEtQISNLNDKLASLNrkYDQVceEKVSAKDEKELLHLNIEQEIRDQ--KERCDKSLTTIMELQQRIQE 1286
Cdd:COG5022  1353 --------KDDLN-KLDELLDACYSLN--PAEI--QNLKSRYDPADKENNLPKEILKKieALLIKQELQLSLEGKDETEV 1419

                         570       580       590
                  ....*....|....*....|....*....|..
gi 564364067 1287 SAKQIEAKDNKITELLNDVERLKQALNGLSQL 1318
Cdd:COG5022  1420 HLSEIFSEEKSLISLDRNSIYKEEVLSSLSAL 1451
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 473-1066 9.85e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 9.85e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   473 EDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTN-EAATGSHRvieELREQLKDMKGKYEGASAEVGKLR 551
Cdd:TIGR04523  162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNlKKKIQKNK---SLESQISELKKQNNQLKDNIEKKQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   552 NQIKQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVTELEGQLKELGAKLalsvptetfESMKSSLSNDIS 631
Cdd:TIGR04523  239 QEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEI---------SDLNNQKEQDWN 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   632 EKAKrlaevgrdyessqGEIRQLKRDLESVRAQhirPEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLYADNK 711
Cdd:TIGR04523  310 KELK-------------SELKNQEKKLEEIQNQ---ISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   712 LLNQQVHSLTVEMKTRyvplrvseemkkahDVNVEDLNKKLSDATQRYAEKKLEAERLLAENDKLTKNVSRLEAVFvapE 791
Cdd:TIGR04523  374 KLKKENQSYKQEIKNL--------------ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETI---I 436

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   792 KHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSsqyvpaKTHEEVKaSLSSTLEKTNRALLDSK 871
Cdd:TIGR04523  437 KNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLE------QKQKELK-SKEKELKKLNEEKKELE 509

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   872 KRLDDTSQEFSKLREENEvlrrNLENVQNQMKADYVSLEEHSRKM--NMANQSLKEAQDahtalladyrQGQEEIVTLHA 949
Cdd:TIGR04523  510 EKVKDLTKKISSLKEKIE----KLESEKKEKESKISDLEDELNKDdfELKKENLEKEID----------EKNKEIEELKQ 575

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   950 EIKAQKKELDTIQECIKlkyaplsrmeecerKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELK 1029
Cdd:TIGR04523  576 TQKSLKKKQEEKQELID--------------QKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKN 641

                          570       580       590
                   ....*....|....*....|....*....|....*..
gi 564364067  1030 DRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDV 1066
Cdd:TIGR04523  642 KLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDI 678
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 632-1187 9.93e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.17  E-value: 9.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   632 EKAKRLAEVGRDYESSQGEIRQLKRDL-ESVRAQHIRPEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLYADN 710
Cdd:pfam01576   19 ERQQKAESELKELEKKHQQLCEEKNALqEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQLQNEK 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   711 KLLNQQVHSLTVEM--------KTRYVPLRVSEEMKKAHD--VNVEDLNKKLSDATQRYAEKKLEAERLLAENDKLTKNV 780
Cdd:pfam01576   99 KKMQQHIQDLEEQLdeeeaarqKLQLEKVTTEAKIKKLEEdiLLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSL 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   781 SRL----EAVFVAPE------------------KHEKELMGLKSNIAELKMQLCELNKKCG------------------- 819
Cdd:pfam01576  179 SKLknkhEAMISDLEerlkkeekgrqelekakrKLEGESTDLQEQIAELQAQIAELRAQLAkkeeelqaalarleeetaq 258

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   820 --EGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKASLSSTLEKTNRALLDSkkrLDDTS--QEFSKLRE-ENEVLRRN 894
Cdd:pfam01576  259 knNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDT---LDTTAaqQELRSKREqEVTELKKA 335

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   895 LENVQNQMKADYVSL-EEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKA-QKKELDTIQECIKLKyapl 972
Cdd:pfam01576  336 LEEETRSHEAQLQEMrQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTlQQAKQDSEHKRKKLE---- 411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   973 SRMEECERKFKATEKAlKEQLSEQTHKGQVRDEEVKKGKQENE----RLRKDLAALQKELKDRNVL-------------- 1034
Cdd:pfam01576  412 GQLQELQARLSESERQ-RAELAEKLSKLQSELESVSSLLNEAEgkniKLSKDVSSLESQLQDTQELlqeetrqklnlstr 490

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1035 --------------VEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQ 1100
Cdd:pfam01576  491 lrqledernslqeqLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDK 570

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1101 VEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQK 1180
Cdd:pfam01576  571 LEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEEALE 650


                   ....*..
gi 564364067  1181 KTKEVSK 1187
Cdd:pfam01576  651 AKEELER 657
PHA03100 PHA03100
ankyrin repeat protein; Provisional
 125-239 1.03e-05

ankyrin repeat protein; Provisional


Pssm-ID: 222984 [Multi-domain]  Cd Length: 422  Bit Score: 49.66  E-value: 1.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  125 LHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQM-----CRPTICQLLIDRGADVNSRDKQNRTALM--LGCEY 197
Cdd:PHA03100   39 LYLAKEARNIDVVKILLDNGADINSSTKNNSTPLHYLSNIkynltDVKEIVKLLLEYGANVNAPDNNGITPLLyaISKKS 118

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 564364067  198 GCRDAVEVLVRNGADLTLLDALGHDSSYYARIG--DNLDILNLL 239
Cdd:PHA03100  119 NSYSIVEYLLDNGANVNIKNSDGENLLHLYLESnkIDLKILKLL 162
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 822-1056 1.03e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  822 QEKIRALMSENTSLKKTLSSQyvpakthEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQ 901
Cdd:COG4942    26 EAELEQLQQEIAELEKELAAL-------KKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  902 MKADYVSLEEHSRKMNMANQS-----LKEAQDAHTAL--LADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSR 974
Cdd:COG4942    99 LEAQKEELAELLRALYRLGRQpplalLLSPEDFLDAVrrLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  975 MEEcerKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDrnVLVEEAREAERALSRKTEELGK 1054
Cdd:COG4942   179 LLA---ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR--LEAEAAAAAERTPAAGFAALKG 253


                  ..
gi 564364067 1055 QL 1056
Cdd:COG4942   254 KL 255
PRK01156 PRK01156
chromosome segregation protein; Provisional
 622-1190 1.08e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.29  E-value: 1.08e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  622 MKSSLSNDISEKAKRLAEVgRDYESSQGEIRQLKRDLESVRAQhirPEEHEQLRSRLEQKSGEL---GKKVTELTLKNQT 698
Cdd:PRK01156  140 MDSLISGDPAQRKKILDEI-LEINSLERNYDKLKDVIDMLRAE---ISNIDYLEEKLKSSNLELeniKKQIADDEKSHSI 215

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  699 LQKEVEKLYADNKLLNQQVHSLTVEMKTryvpLRVSEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLA-ENDKLT 777
Cdd:PRK01156  216 TLKEIERLSIEYNNAMDDYNNLKSALNE----LSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKiINDPVY 291

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  778 KNVSRLEAVFvapeKHEKELMGLKSNIAELKMQLC--ELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKAS 855
Cdd:PRK01156  292 KNRNYINDYF----KYKNDIENKKQILSNIDAEINkyHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNS 367

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  856 LSSTLEKTNRALLDSKKRLDDTSQEFSK-----------LREENEVLRRNLE-------NVQNQMKADYVSLEEHSRKMN 917
Cdd:PRK01156  368 YLKSIESLKKKIEEYSKNIERMSAFISEilkiqeidpdaIKKELNEINVKLQdisskvsSLNQRIRALRENLDELSRNME 447

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  918 MANQSLK-------EAQDAHTALLADYrqgQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALK 990
Cdd:PRK01156  448 MLNGQSVcpvcgttLGEEKSNHIINHY---NEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKSINEYNKI 524

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  991 EQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDR------NVLVEEAREAERALSRKTEELGKQLKELSQKYS 1064
Cdd:PRK01156  525 ESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEDLDSkrtswlNALAVISLIDIETNRSRSNEIKKQLNDLESRLQ 604

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1065 DVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQK 1144
Cdd:PRK01156  605 EIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLK 684

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*.
gi 564364067 1145 SSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQT 1190
Cdd:PRK01156  685 KSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 287-1276 1.09e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.05  E-value: 1.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   287 EMENEDLKEKLRKIQQEQRILldkvnglqLQLNEEVMVADDLESEREKLKSLLaaKEKQHEESLRTIEALKNRFKYFESD 366
Cdd:TIGR00606  244 ENELDPLKNRLKEIEHNLSKI--------MKLDNEIKALKSRKKQMEKDNSEL--ELKMEKVFQGTDEQLNDLYHNHQRT 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   367 hpgpgSYSSNRKEDMLHKQGQMYTADSQctspgvpphmqsrsmlrplelSLPSQTSYSENEILKKELEAMRTFCDSAKQD 446
Cdd:TIGR00606  314 -----VREKERELVDCQRELEKLNKERR---------------------LLNQEKTELLVEQGRLQLQADRHQEHIRARD 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   447 RLKLQNelahkvaeckALALECERVKEDSDEQIkQLEDALKDVQKRMyESEGKVKQMQTHFLALKEHLTNEAATgshRVI 526
Cdd:TIGR00606  368 SLIQSL----------ATRLELDGFERGPFSER-QIKNFHTLVIERQ-EDEAKTAAQLCADLQSKERLKQEQAD---EIR 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   527 EELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKrdesRLVEENKRLQKecstceidrerrgrrvtelegQLKEL 606
Cdd:TIGR00606  433 DEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSD----RILELDQELRK---------------------AEREL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   607 gAKLALSVPTETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAqhiRPEEHEQLRSRLEQKSGELG 686
Cdd:TIGR00606  488 -SKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKD---KMDKDEQIRKIKSRHSDELT 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   687 KKVTEltlknqtlqkeveklYADNKLLNQQVHSLTVEMKTRYVPLRvseemkkahdvnveDLNKKLSDATQRYAEKKLEA 766
Cdd:TIGR00606  564 SLLGY---------------FPNKKQLEDWLHSKSKEINQTRDRLA--------------KLNKELASLEQNKNHINNEL 614

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   767 ERLLAENDKLTKNVSRLeavfVAPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYvpa 846
Cdd:TIGR00606  615 ESKEEQLSSYEDKLFDV----CGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVF--- 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   847 ktheEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQslkea 926
Cdd:TIGR00606  688 ----QTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNR----- 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   927 qdahtalladyrqgqeEIVTLHAEIKAQKKELDTI---QECIKLKYAPLSRMEECERKFKATEKALKEQLSE-QTHKGQV 1002
Cdd:TIGR00606  759 ----------------DIQRLKNDIEEQETLLGTImpeEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKlQGSDLDR 822

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1003 RDEEVKKGKQE-NERLRKdlaaLQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLvEEKAKQT 1081
Cdd:TIGR00606  823 TVQQVNQEKQEkQHELDT----VVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQL-VELSTEV 897

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1082 SEILAAQNLLQKQPVPLEQvealktSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQ-----L 1156
Cdd:TIGR00606  898 QSLIREIKDAKEQDSPLET------FLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQdgkddY 971

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1157 KEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQA---LKNLETREVVDmSKYKATKNDLETQISNLNDKLAS 1233
Cdd:TIGR00606  972 LKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQerwLQDNLTLRKRE-NELKEVEEELKQHLKEMGQMQVL 1050

                          970       980       990      1000
                   ....*....|....*....|....*....|....*....|...
gi 564364067  1234 LNRKYDQVCEEKVSAKDEKELLHLNIEQEIRDQKERCDKSLTT 1276
Cdd:TIGR00606 1051 QMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELRE 1093
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1038-1275 1.18e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1038 AREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKqpvpleqvealktslngtiehLKE 1117
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRA---------------------LEQ 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1118 ELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKAS-----------LREKEEESQKKTKEVS 1186
Cdd:COG4942    77 ELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEdfldavrrlqyLKYLAPARREQAEELR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1187 KLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKELLHLNIEQEIRDQ 1266
Cdd:COG4942   157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236


                  ....*....
gi 564364067 1267 KERCDKSLT 1275
Cdd:COG4942   237 AAAAERTPA 245
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 617-1366 1.19e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.12  E-value: 1.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   617 ETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQ----LKRDLESVRAQH-----IRPEE---HEQLRSRLEQKSGE 684
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQsvidLQTKLQEMQMERdamadIRRREsqsQEDLRNQLQNTVHE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   685 L--GKKVTELTLKNQTLQ-KEVEKLYADNKLLNQQVHSLTVEMKtryvplrvSEEMKKAHDVNvedlnkklSDATQRYAE 761
Cdd:pfam15921  154 LeaAKCLKEDMLEDSNTQiEQLRKMMLSHEGVLQEIRSILVDFE--------EASGKKIYEHD--------SMSTMHFRS 217

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   762 KKLEAERLLAEndkLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQlcelnkkcgEGQEKIRALMSENTSLKKTLSS 841
Cdd:pfam15921  218 LGSAISKILRE---LDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQ---------QHQDRIEQLISEHEVEITGLTE 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   842 QYVPAKTH-EEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENvqnqmkadyvSLEEHSRKMNMAN 920
Cdd:pfam15921  286 KASSARSQaNSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYED----------KIEELEKQLVLAN 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   921 QSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKlkyaplsRMEECERKFKATEKALKEQLSEQTHKG 1000
Cdd:pfam15921  356 SELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNK-------RLWDRDTGNSITIDHLRRELDDRNMEV 428

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1001 QVRDEEVKKGKQENE-RLRKDLAALQ---KELKDRNVLVEEAREAERALSRKTEELGKQ---LKELSQKYSDVKS---ER 1070
Cdd:pfam15921  429 QRLEALLKAMKSECQgQMERQMAAIQgknESLEKVSSLTAQLESTKEMLRKVVEELTAKkmtLESSERTVSDLTAslqEK 508

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1071 EKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLL-ENQKSSSVT 1149
Cdd:pfam15921  509 ERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVgQHGRTAGAM 588

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1150 LADHLQLKEALE------KEVGIMK----ASLREKE-----------------EESQKKTKEVSK----LQTEVQNTKQA 1198
Cdd:pfam15921  589 QVEKAQLEKEINdrrlelQEFKILKdkkdAKIRELEarvsdlelekvklvnagSERLRAVKDIKQerdqLLNEVKTSRNE 668

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1199 LKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDQ---VCEEKVSAKDEKELLHLNIEQEIRDQKERCDKSLT 1275
Cdd:pfam15921  669 LNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQtrnTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQS 748

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1276 TIMELQQRIQESAKQ---IEAKDNKITELLNDVERLKQALNGLSQLTYSSggpTKRQSQLVDTLQQRVRDLQQQLADA-- 1350
Cdd:pfam15921  749 KIQFLEEAMTNANKEkhfLKEEKNKLSQELSTVATEKNKMAGELEVLRSQ---ERRLKEKVANMEVALDKASLQFAECqd 825

                          810
                   ....*....|....*...
gi 564364067  1351 --DRQHQEVIAIYRTHLL 1366
Cdd:pfam15921  826 iiQRQEQESVRLKLQHTL 843
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
865-1363 2.01e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 2.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  865 RALLDSKKRLDDTSQEFSKLREENEVLRRnLENVQNQMKADYVSLEEHSRKMNMAN-----QSLKEAQDAHTALLADYRQ 939
Cdd:COG4913   228 DALVEHFDDLERAHEALEDAREQIELLEP-IRELAERYAAARERLAELEYLRAALRlwfaqRRLELLEAELEELRAELAR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  940 GQEEIVTLHAEIKAQKKELDTIQEciKLKYAPLSRMEECERKFKATEKALKE------QLSEQTHKGQVRDEEVKKGKQE 1013
Cdd:COG4913   307 LEAELERLEARLDALREELDELEA--QIRGNGGDRLEQLEREIERLERELEErerrraRLEALLAALGLPLPASAEEFAA 384

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1014 N-ERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSE----REKLVEEKAKQTSEILAAQ 1088
Cdd:COG4913   385 LrAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARllalRDALAEALGLDEAELPFVG 464

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1089 NLLQKQP---------------------VPLEQVEALKTSLNGTieHLKEELRSkerclereqQAVSQLQQLLENQKSSS 1147
Cdd:COG4913   465 ELIEVRPeeerwrgaiervlggfaltllVPPEHYAAALRWVNRL--HLRGRLVY---------ERVRTGLPDPERPRLDP 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1148 VTLADHLQLKE-----ALEKEV-------------------------GIMKASLREKEEESQKKTKEVSKLQtevQNTKQ 1197
Cdd:COG4913   534 DSLAGKLDFKPhpfraWLEAELgrrfdyvcvdspeelrrhpraitraGQVKGNGTRHEKDDRRRIRSRYVLG---FDNRA 610

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1198 ALKNLETRevvdMSKYKATKNDLETQISNLNDKLASLNRKYD--QVCEEKVSAKDEKELLHLNIeQEIRDQKERCDKSLT 1275
Cdd:COG4913   611 KLAALEAE----LAELEEELAEAEERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREI-AELEAELERLDASSD 685

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1276 TIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLtyssggpTKRQSQLVDTLQQRVRDLQQQLADADRQHQ 1355
Cdd:COG4913   686 DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEE-------LDELQDRLEAAEDLARLELRALLEERFAAA 758


                  ....*...
gi 564364067 1356 EVIAIYRT 1363
Cdd:COG4913   759 LGDAVERE 766
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 871-1212 2.05e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.20  E-value: 2.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   871 KKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADYRQ--------GQE 942
Cdd:pfam02463  172 KEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDllqellrdEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   943 EIVTLHAEIKAQKKELDTIQECIKLKyapLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKdla 1022
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEE---EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK--- 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1023 aLQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQVE 1102
Cdd:pfam02463  326 -AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1103 ALKTSLNG---TIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEvgimkasLREKEEESQ 1179
Cdd:pfam02463  405 KEAQLLLElarQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELK-------KSEDLLKET 477

                          330       340       350
                   ....*....|....*....|....*....|...
gi 564364067  1180 KKTKEVSKLQTEVQNTKQALKNLETREVVDMSK 1212
Cdd:pfam02463  478 QLVKLQEQLELLLSRQKLEERSQKESKARSGLK 510
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 938-1277 2.13e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.97  E-value: 2.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   938 RQGQEEIVTLHAEIKAQKKE--LDTIQECIKLKYAPLSRMEECERKfkATEKALKEQLSEQTHK--GQVRDEEVKKgkqE 1013
Cdd:pfam17380  287 RQQQEKFEKMEQERLRQEKEekAREVERRRKLEEAEKARQAEMDRQ--AAIYAEQERMAMERERelERIRQEERKR---E 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1014 NERLRKDLAALQkelkdrnvlVEEAREAER---ALSRKTEELGKQLkELSQKYSDVKSEREKLVEEKAKQTSEILAAQ-N 1089
Cdd:pfam17380  362 LERIRQEEIAME---------ISRMRELERlqmERQQKNERVRQEL-EAARKVKILEEERQRKIQQQKVEMEQIRAEQeE 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1090 LLQKQPVPLEQvealktslngtiEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKA 1169
Cdd:pfam17380  432 ARQREVRRLEE------------ERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEK 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1170 SLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDqvceekvSAK 1249
Cdd:pfam17380  500 ELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLE-------AME 572

                          330       340
                   ....*....|....*....|....*...
gi 564364067  1250 DEKELLHLNIEQEIRDQKERCDKSLTTI 1277
Cdd:pfam17380  573 REREMMRQIVESEKARAEYEATTPITTI 600
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 862-1348 2.77e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.81  E-value: 2.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   862 KTNRALLDSKKRL--DDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQdahtaLLADYRQ 939
Cdd:TIGR00618  193 HGKAELLTLRSQLltLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQ-----LLKQLRA 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   940 GQEEIVTLHAEIKAQKKELDtiQECIKLKYAPLS-RMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKK--GKQENER 1016
Cdd:TIGR00618  268 RIEELRAQEAVLEETQERIN--RARKAAPLAAHIkAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQqsSIEEQRR 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1017 LRKDLAALQKELKDRN---VLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEiLAAQNLLQK 1093
Cdd:TIGR00618  346 LLQTLHSQEIHIRDAHevaTSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTR-TSAFRDLQG 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1094 QPVPLEQVEALktslngtiehlkeelrskerclerEQQAVSQLQQLLENQksssvtladhLQLKEALEKEVGIMKASLRE 1173
Cdd:TIGR00618  425 QLAHAKKQQEL------------------------QQRYAELCAAAITCT----------AQCEKLEKIHLQESAQSLKE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1174 KEEESQKK---TKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNR-KYDQVCEEKVSAK 1249
Cdd:TIGR00618  471 REQQLQTKeqiHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTyAQLETSEEDVYHQ 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1250 DEKELLHLnieQEIRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQ 1329
Cdd:TIGR00618  551 LTSERKQR---ASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDL 627

                          490
                   ....*....|....*....
gi 564364067  1330 SQLVDTLQQRVRDLQQQLA 1348
Cdd:TIGR00618  628 QDVRLHLQQCSQELALKLT 646
PRK01156 PRK01156
chromosome segregation protein; Provisional
 774-1317 2.85e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 48.74  E-value: 2.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  774 DKLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKT---LSSQYVPAKTHE 850
Cdd:PRK01156  176 DMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSAlneLSSLEDMKNRYE 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  851 EVKASLSSTLEktnrALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAH 930
Cdd:PRK01156  256 SEIKTAESDLS----MELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKL 331

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  931 TALLADYRQgQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKg 1010
Cdd:PRK01156  332 SVLQKDYND-YIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKK- 409

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1011 kqENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLK--ELSQKYSDVKSER--EKLVEEKAKQTSEILA 1086
Cdd:PRK01156  410 --ELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVcpVCGTTLGEEKSNHiiNHYNEKKSRLEEKIRE 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1087 AQNLLQKQPVPLEQVEALKTSLNGtiehlkeelrSKERCLEREQQAVSQLQQLLENQKSSSVTLAD-HLQLKEALEKEVG 1165
Cdd:PRK01156  488 IEIEVKDIDEKIVDLKKRKEYLES----------EEINKSINEYNKIESARADLEDIKIKINELKDkHDKYEEIKNRYKS 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1166 IMKASLREKEEE-----SQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASLNRKYDQ 1240
Cdd:PRK01156  558 LKLEDLDSKRTSwlnalAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNE 637

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1241 VCEEKVSAKDEKELLHlNIEQEIRDQKERCDKSLTT---IMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQ 1317
Cdd:PRK01156  638 IQENKILIEKLRGKID-NYKKQIAEIDSIIPDLKEItsrINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSD 716
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
932-1132 2.95e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 2.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  932 ALLADYRQGQEEIVTLHAEIKAQKKELDTIQEcIKLKYAPLSRMEECERKFKATEKALkEQLseqthkgqvrdeevkkgK 1011
Cdd:COG4913   614 ALEAELAELEEELAEAEERLEALEAELDALQE-RREALQRLAEYSWDEIDVASAEREI-AEL-----------------E 674

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1012 QENERLRK---DLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQ 1088
Cdd:COG4913   675 AELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEER 754

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 564364067 1089 NLLQKQPvplEQVEALKTSLNGTIEHLKEELRSKERCLEREQQA 1132
Cdd:COG4913   755 FAAALGD---AVERELRENLEERIDALRARLNRAEEELERAMRA 795
PTZ00121 PTZ00121
MAEBL; Provisional
 877-1311 4.17e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 4.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  877 TSQEFSKLREENEVLRRNLENVQN----QMKADYVSLEEHSRKMNMANQsLKEAQDAHTALLADYRQGQEEIVTLHAEIK 952
Cdd:PTZ00121 1093 TEEAFGKAEEAKKTETGKAEEARKaeeaKKKAEDARKAEEARKAEDARK-AEEARKAEDAKRVEIARKAEDARKAEEARK 1171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  953 AQK-KELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQLSEQTHKGQ--------VRDEEVKKG-----KQENERLR 1018
Cdd:PTZ00121 1172 AEDaKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEdakkaeavKKAEEAKKDaeeakKAEEERNN 1251

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1019 KDLAALQKELKDRNVLVEEAREAERAlsRKTEELgKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPL 1098
Cdd:PTZ00121 1252 EEIRKFEEARMAHFARRQAAIKAEEA--RKADEL-KKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAK 1328

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1099 EQVEALKTSLN-----GTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSS-------VTLADHLQLK--------- 1157
Cdd:PTZ00121 1329 KKADAAKKKAEeakkaAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAakkkaeeKKKADEAKKKaeedkkkad 1408

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1158 EALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATkndlETQISNLNDKLASLNRK 1237
Cdd:PTZ00121 1409 ELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE----EAKKADEAKKKAEEAKK 1484

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564364067 1238 YDQVCEEKVSAKDEKEllHLNIEQEIRDQKERCDKSLTTIMELQQRIQESAKQIE----AKDNKITELLNDVERLKQA 1311
Cdd:PTZ00121 1485 ADEAKKKAEEAKKKAD--EAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADeakkAEEKKKADELKKAEELKKA 1560
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1048-1253 5.07e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 47.13  E-value: 5.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1048 KTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLE 1127
Cdd:COG3883    17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1128 REQQAVSQLQQLLenqksSSVTLADHLQlkealekevgimKASLREKEEESQKKT-KEVSKLQTEVQNTKQALKNLETRE 1206
Cdd:COG3883    97 RSGGSVSYLDVLL-----GSESFSDFLD------------RLSALSKIADADADLlEELKADKAELEAKKAELEAKLAEL 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 564364067 1207 VVDMSKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKE 1253
Cdd:COG3883   160 EALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELA 206
TRPV5-6 cd22192
Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and ...
 92-220 5.10e-05

Transient Receptor Potential channel, Vanilloid subfamily (TRPV), types 5 and 6; TRPV5 and TRPV6 (TRPV5/6) are two homologous members within the vanilloid subfamily of the transient receptor potential (TRP) family. TRPV5 and TRPV6 show only 30-40% homology with other members of the TRP family and have unique properties that differentiates them from other TRP channels. They mediate calcium uptake in epithelia and their expression is dramatically increased in numerous types of cancer. The structure of TRPV5/6 shows the typical topology features of all TRP family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6, which is predicted to form the Ca2+ pore, and large intracellular N- and C-terminal domains. The N-terminal domain of TRPV5/6 contains three ankyrin repeats. This structural element is present in several proteins and plays a role in protein-protein interactions. The N- and C-terminal tails of TRPV5/6 each contain an internal PDZ motif which can function as part of a molecular scaffold via interaction with PDZ-domain containing proteins. A major difference between the properties of TRPV5 and TRPV6 is in their tissue distribution: TRPV5 is predominantly expressed in the distal convoluted tubules (DCT) and connecting tubules (CNT) of the kidney, with limited expression in extrarenal tissues. In contrast, TRPV6 has a broader expression pattern such as expression in the intestine, kidney, placenta, epididymis, exocrine tissues, and a few other tissues.


Pssm-ID: 411976 [Multi-domain]  Cd Length: 609  Bit Score: 47.70  E-value: 5.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   92 LHLAAKYGHALCLQKLLQYNcpteHVDLQ-----GRTALHDAAMADCPSSIQLLCDhgasvNAKDI----------DGRT 156
Cdd:cd22192    21 LLLAAKENDVQAIKKLLKCP----SCDLFqrgalGETALHVAALYDNLEAAVVLME-----AAPELvnepmtsdlyQGET 91

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564364067  157 PLVLATQMCRPTICQLLIDRGADVNSRD------KQNRTALMLGCEY--------GCRDAVEVLVRNGADLTLLDALG 220
Cdd:cd22192    92 ALHIAVVNQNLNLVRELIARGADVVSPRatgtffRPGPKNLIYYGEHplsfaacvGNEEIVRLLIEHGADIRAQDSLG 169
Ank_2 pfam12796
Ankyrin repeats (3 copies);
25-85 6.21e-05

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 43.18  E-value: 6.21e-05
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564364067    25 LMKAAERGDVEKVSSILAKKGVhpgKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRD 85
Cdd:pfam12796   34 LHLAAKNGHLEIVKLLLEHADV---NLKDNGRTALHYAARSGHLEIVKLLLEKGADINVKD 91
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1117-1373 6.60e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 6.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1117 EELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLqlkEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTK 1196
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL---AALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1197 QALKNLETREVVDMSKYkatkndletQISNLNDKLASLnrkydqvceekVSAKDEKELLHL--NIEQEIRDQKERCDKSL 1274
Cdd:COG4942    97 AELEAQKEELAELLRAL---------YRLGRQPPLALL-----------LSPEDFLDAVRRlqYLKYLAPARREQAEELR 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1275 TTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQLTYSSGGPTKRQSQLVDTLQQRVRDLQQQLADADRQH 1354
Cdd:COG4942   157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236

                         250
                  ....*....|....*....
gi 564364067 1355 QEVIAIYRTHLLSAAQGHM 1373
Cdd:COG4942   237 AAAAERTPAAGFAALKGKL 255
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 780-1357 7.21e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.53  E-value: 7.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   780 VSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYV-PAKTHEEVKASLSS 858
Cdd:pfam12128  243 FTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNgELSAADAAVAKDRS 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   859 TLEktnrALLDSKKRLDDTSQEFSKLREENEVLRRN-LENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADY 937
Cdd:pfam12128  323 ELE----ALEDQHGAFLDADIETAAADQEQLPSWQSeLENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDK 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   938 RQGQ-EEIVTLHAEIKAQKKELDtiQECIKLKYAPLSRMEECERKFKATEKALKEQL------SEQTHKGQVRDEEVKKG 1010
Cdd:pfam12128  399 LAKIrEARDRQLAVAEDDLQALE--SELREQLEAGKLEFNEEEYRLKSRLGELKLRLnqatatPELLLQLENFDERIERA 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1011 KQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKA---KQTSEILAA 1087
Cdd:pfam12128  477 REEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEApdwEQSIGKVIS 556

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1088 QNLLQK---QPVPLEQVEALKTSLNGTIEHLK-----------EELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADH 1153
Cdd:pfam12128  557 PELLHRtdlDPEVWDGSVGGELNLYGVKLDLKridvpewaaseEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEK 636

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1154 LQLKEALEkevgimKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSK-YKATKNDLETQISNLNDKLA 1232
Cdd:pfam12128  637 ASREETFA------RTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAqLKQLDKKHQAWLEEQKEQKR 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1233 SLNRKYDQVCEEKVSAKD--------EKELLHLNIEQEIRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLND 1304
Cdd:pfam12128  711 EARTEKQAYWQVVEGALDaqlallkaAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVR 790

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 564364067  1305 VERLKQALNGLsQLTYSSGGPtKRQSQLVDTlQQRVRDLQQQLAdadRQHQEV 1357
Cdd:pfam12128  791 RQEVLRYFDWY-QETWLQRRP-RLATQLSNI-ERAISELQQQLA---RLIADT 837
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 518-727 8.35e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 8.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  518 AATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVT 597
Cdd:COG4942    14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  598 ELEGQLKELGAKLALSVPTETFESMKSSL-----SNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQHIRPE--- 669
Cdd:COG4942    94 ELRAELEAQKEELAELLRALYRLGRQPPLalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEaer 173

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564364067  670 --------EHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVHSLTVEMKTR 727
Cdd:COG4942   174 aeleallaELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1082-1234 8.44e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 45.69  E-value: 8.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1082 SEILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLkEALE 1161
Cdd:COG1579    17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEY-EALQ 95

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564364067 1162 KEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISNLNDKLASL 1234
Cdd:COG1579    96 KEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168
Ank_4 pfam13637
Ankyrin repeats (many copies);
88-140 9.27e-05

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 41.49  E-value: 9.27e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 564364067    88 GRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLL 140
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLL 53
PRK04778 PRK04778
septation ring formation regulator EzrA; Provisional
 876-1292 1.06e-04

septation ring formation regulator EzrA; Provisional


Pssm-ID: 179877 [Multi-domain]  Cd Length: 569  Bit Score: 46.75  E-value: 1.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  876 DTSQEFSKLREE-NEVLRRNLENVQNQMkadyVSLEEHSRKMNM--ANQSLKEAQDAHTALLADYRQGQEEIvtlhAEIK 952
Cdd:PRK04778   61 QSEEKFEEWRQKwDEIVTNSLPDIEEQL----FEAEELNDKFRFrkAKHEINEIESLLDLIEEDIEQILEEL----QELL 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  953 AQKKELDTiqeciklkyaplsRMEECERKFKAtekaLKEQLSEQTHK-GQVRDEevkkgkqenerLRKDLAALQKELKDR 1031
Cdd:PRK04778  133 ESEEKNRE-------------EVEQLKDLYRE----LRKSLLANRFSfGPALDE-----------LEKQLENLEEEFSQF 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1032 NVLVE-----EAREAERALSRKTEELGKQLKELSQKYSDVKSErekLVEekakQTSEILAAQNLLQKQPVPLEQVEalkt 1106
Cdd:PRK04778  185 VELTEsgdyvEAREILDQLEEELAALEQIMEEIPELLKELQTE---LPD----QLQELKAGYRELVEEGYHLDHLD---- 253

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1107 sLNGTIEHLKEELrskerclereQQAVSQLQQL-LENQKSSSVTLADHL-QLKEALEKEVgimkaslrEKEEESQKKTKE 1184
Cdd:PRK04778  254 -IEKEIQDLKEQI----------DENLALLEELdLDEAEEKNEEIQERIdQLYDILEREV--------KARKYVEKNSDT 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1185 VSKLQTEVQNTKQALKnLETREVvdMSKYKATKNDLETQiSNLNDKLASLNRKYDQVCEEKvsakDEKELLHlnieQEIR 1264
Cdd:PRK04778  315 LPDFLEHAKEQNKELK-EEIDRV--KQSYTLNESELESV-RQLEKQLESLEKQYDEITERI----AEQEIAY----SELQ 382

                         410       420
                  ....*....|....*....|....*...
gi 564364067 1265 DQKERCDKSLTTIMELQQRIQESAKQIE 1292
Cdd:PRK04778  383 EELEEILKQLEEIEKEQEKLSEMLQGLR 410
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 846-1164 1.22e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.87  E-value: 1.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  846 AKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKL--REE---------NEVLRRNLENVQNQMKAD-YVS-LEEH 912
Cdd:COG3096   280 RRELSERALELRRELFGARRQLAEEQYRLVEMARELEELsaRESdleqdyqaaSDHLNLVQTALRQQEKIErYQEdLEEL 359

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  913 SRKMNMANQSLKEAQDAHTAL-----------------LADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRM 975
Cdd:COG3096   360 TERLEEQEEVVEEAAEQLAEAearleaaeeevdslksqLADYQQALDVQQTRAIQYQQAVQALEKARALCGLPDLTPENA 439

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  976 EECERKFKATEKALKEQLSEQTHKGQVRD----------EEVKKGKQENER---------LRKDLAALQKELKDRNVLVE 1036
Cdd:COG3096   440 EDYLAAFRAKEQQATEEVLELEQKLSVADaarrqfekayELVCKIAGEVERsqawqtareLLRRYRSQQALAQRLQQLRA 519

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1037 EAREAERALSRKtEELGKQLKELSQKYS----------DVKSEREKLVEEKAKQTSEILAAQNLLQKQpvpLEQVEALKT 1106
Cdd:COG3096   520 QLAELEQRLRQQ-QNAERLLEEFCQRIGqqldaaeeleELLAELEAQLEELEEQAAEAVEQRSELRQQ---LEQLRARIK 595

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564364067 1107 SL----------NGTIEHLKEELrskERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEV 1164
Cdd:COG3096   596 ELaarapawlaaQDALERLREQS---GEALADSQEVTAAMQQLLEREREATVERDELAARKQALESQI 660
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 480-1362 1.45e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 46.32  E-value: 1.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   480 KQLEDALKDVQKRMYESEGKVKQMQThfLALKEHLTNEAATGSHRVIEELREQLKDMKGKYEGASAEvgkLRNQIKQSEM 559
Cdd:pfam01576  155 KLLEERISEFTSNLAEEEEKAKSLSK--LKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTD---LQEQIAELQA 229

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   560 LVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVTELEGQLKELGAKLALS-VPTETFESMKSSLSNDIsEKAKRLA 638
Cdd:pfam01576  230 QIAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESErAARNKAEKQRRDLGEEL-EALKTEL 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   639 EVGRDYESSQGEIR--------QLKRDLESVRAQHirPEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLYADN 710
Cdd:pfam01576  309 EDTLDTTAAQQELRskreqevtELKKALEEETRSH--EAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESEN 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   711 KllnqqvhSLTVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLAENDKLTKNVSRLEAVFVap 790
Cdd:pfam01576  387 A-------ELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNI-- 457

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   791 eKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQyvpakthEEVKASLSSTLEKTNRALLDS 870
Cdd:pfam01576  458 -KLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEE-------EEAKRNVERQLSTLQAQLSDM 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   871 KKRLDDTSQEFSKLREENEVLRRNLENVQNQMK---ADYVSLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTL 947
Cdd:pfam01576  530 KKKLEEDAGTLEALEEGKKRLQRELEALTQQLEekaAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQM 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   948 HAEIKAqkkeldtiqecIKLKYAPLSRMEECERKFKATeKALkeQLSEQTHKGQVRDEEVKKgkqENERLRKDLAALQKE 1027
Cdd:pfam01576  610 LAEEKA-----------ISARYAEERDRAEAEAREKET-RAL--SLARALEEALEAKEELER---TNKQLRAEMEDLVSS 672

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1028 LKDRNVLVEEAREAERALSRKTEELGKQLKELS---QKYSDVKSEREKLVEEKAKQTSEILAAQNllqkqpvplEQVEAL 1104
Cdd:pfam01576  673 KDDVGKNVHELERSKRALEQQVEEMKTQLEELEdelQATEDAKLRLEVNMQALKAQFERDLQARD---------EQGEEK 743

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1105 KTSLNGTIEHLKEELRSKERclEREQQAVSQLQQLLENQKSSSVTLADHLQLKEA---LEKEVGIMKASLREKEE----- 1176
Cdd:pfam01576  744 RRQLVKQVRELEAELEDERK--QRAQAVAAKKKLELDLKELEAQIDAANKGREEAvkqLKKLQAQMKDLQRELEEarasr 821

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1177 --------ESQKKTK----EVSKLQTEVQNTKQALKNLETR------EVVDMSKYKAT----KNDLETQISNLNDKLASL 1234
Cdd:pfam01576  822 deilaqskESEKKLKnleaELLQLQEDLAASERARRQAQQErdeladEIASGASGKSAlqdeKRRLEARIAQLEEELEEE 901

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1235 ----------NRKYDQVCEEkVSAKDEKELLHLNIEQEIRDQKERCDKSLTTIM-ELQQRIQESAKQ----IEAKDNKIT 1299
Cdd:pfam01576  902 qsntellndrLRKSTLQVEQ-LTTELAAERSTSQKSESARQQLERQNKELKAKLqEMEGTVKSKFKSsiaaLEAKIAQLE 980

                          890       900       910       920       930       940       950
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564364067  1300 ELLNDVERLKQALNGLSQLTYSSGGPT-------KRQSQL----VDTLQQRVRDLQQQLADADRQHQEVIAIYR 1362
Cdd:pfam01576  981 EQLEQESRERQAANKLVRRTEKKLKEVllqvedeRRHADQykdqAEKGNSRMKQLKRQLEEAEEEASRANAARR 1054
COG5022 COG5022
Myosin heavy chain [General function prediction only];
938-1255 1.57e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 46.61  E-value: 1.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  938 RQGQEEIVTLHAEI---------KAQKKELDTIQECIKLKYAplSRMEECERKFKATEKALKE--QLSEQTHKGQVRDEE 1006
Cdd:COG5022   833 RETEEVEFSLKAEVliqkfgrslKAKKRFSLLKKETIYLQSA--QRVELAERQLQELKIDVKSisSLKLVNLELESEIIE 910

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1007 VKKGKQENERLR-KDLAALQKELKD--RNVLVEEAREAERALSRKTEEL---GKQLKELSQKYSDVKSEREKLVEEKAKQ 1080
Cdd:COG5022   911 LKKSLSSDLIENlEFKTELIARLKKllNNIDLEEGPSIEYVKLPELNKLhevESKLKETSEEYEDLLKKSTILVREGNKA 990

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1081 TSEILAAQNLLQKQpvpLEQVEALKTSlngtiehlKEELRSKERCLEREQQAVSQ-------LQQLLENQKSSSVTLADH 1153
Cdd:COG5022   991 NSELKNFKKELAEL---SKQYGALQES--------TKQLKELPVEVAELQSASKIissesteLSILKPLQKLKGLLLLEN 1059

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1154 LQLKEALeKEVGIMK-ASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLET-REVVDMSKYKATKNDLETQISnlndkl 1231
Cdd:COG5022  1060 NQLQARY-KALKLRReNSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKpANVLQFIVAQMIKLNLLQEIS------ 1132

                         330       340
                  ....*....|....*....|....
gi 564364067 1232 aSLNRKYDQVCEEKVSAKDEKELL 1255
Cdd:COG5022  1133 -KFLSQLVNTLEPVFQKLSVLQLE 1155
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 983-1198 2.42e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 2.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  983 KATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKdrnvlveearEAERALSRKTEELGKQLKELsQK 1062
Cdd:COG3883    29 QAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIA----------EAEAEIEERREELGERARAL-YR 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1063 YSDVKSEREKLVEekAKQTSEILAAQNLLQK----QPVPLEQVEALKTSLngtiEHLKEELRSKERCLEREQQAVSQLQQ 1138
Cdd:COG3883    98 SGGSVSYLDVLLG--SESFSDFLDRLSALSKiadaDADLLEELKADKAEL----EAKKAELEAKLAELEALKAELEAAKA 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1139 LLENQKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQA 1198
Cdd:COG3883   172 ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 153-185 2.51e-04

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 39.58  E-value: 2.51e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 564364067   153 DGRTPLVLATQMC-RPTICQLLIDRGADVNSRDK 185
Cdd:pfam00023    1 DGNTPLHLAAGRRgNLEIVKLLLSKGADVNARDK 34
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 93-173 2.51e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 45.66  E-value: 2.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   93 HLAAKyGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQL 172
Cdd:PTZ00322   88 QLAAS-GDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQL 166


                  .
gi 564364067  173 L 173
Cdd:PTZ00322  167 L 167
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
844-1353 2.52e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 2.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  844 VPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENvqnqmkADYVSLEEHSRKMNMANQSL 923
Cdd:COG4913   281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG------NGGDRLEQLEREIERLEREL 354

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  924 KEAQDAHTALladyrqgQEEIVTLHAEIKAQKKELDTIQECIklkyaplsrmeeceRKFKATEKALKEQLSEQTHKgqvR 1003
Cdd:COG4913   355 EERERRRARL-------EALLAALGLPLPASAEEFAALRAEA--------------AALLEALEEELEALEEALAE---A 410

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1004 DEEVKKGKQENERLRKDLAALQKelkdRNVL----VEEAREA-ERALSRKTEELgKQLKELSQkysdVKSEREK------ 1072
Cdd:COG4913   411 EAALRDLRRELRELEAEIASLER----RKSNiparLLALRDAlAEALGLDEAEL-PFVGELIE----VRPEEERwrgaie 481

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1073 ----------LVEEK-AKQTSEILAAQNL--------LQKQPVPLEQVEALKTSLNGTIE--------HLKEELRSKE-- 1123
Cdd:COG4913   482 rvlggfaltlLVPPEhYAAALRWVNRLHLrgrlvyerVRTGLPDPERPRLDPDSLAGKLDfkphpfraWLEAELGRRFdy 561

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1124 RC------LEREQQAVSQLQQLLENQ-----------KSSSVTLADHLQLKEALEKEVgimkASLREKEEESQKKTKEVS 1186
Cdd:COG4913   562 VCvdspeeLRRHPRAITRAGQVKGNGtrhekddrrriRSRYVLGFDNRAKLAALEAEL----AELEEELAEAEERLEALE 637

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1187 KLQTEVQNTKQALKNLETR--EVVDMSKYKATKNDLETQISNL---NDKLASLNRKYDQVCEEKVSAKDEKEllhlnieq 1261
Cdd:COG4913   638 AELDALQERREALQRLAEYswDEIDVASAEREIAELEAELERLdasSDDLAALEEQLEELEAELEELEEELD-------- 709

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1262 EIRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDvERLKQALnglsqltyssggPTKRQSQLVDTLQQRVR 1341
Cdd:COG4913   710 ELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLE-ERFAAAL------------GDAVERELRENLEERID 776

                         570
                  ....*....|..
gi 564364067 1342 DLQQQLADADRQ 1353
Cdd:COG4913   777 ALRARLNRAEEE 788
Ank_4 pfam13637
Ankyrin repeats (many copies);
21-71 2.68e-04

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 39.95  E-value: 2.68e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 564364067    21 YDDRLMKAAERGDVEKVSSILaKKGVHPGKLDVEGRSAFHVVAAKGNLECL 71
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLL-EKGADINAVDGNGETALHFAASNGNVEVL 50
46 PHA02562
endonuclease subunit; Provisional
 710-966 2.83e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.39  E-value: 2.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  710 NKLLNQQVHSLTVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKLSDATQRYAEK----KLEAERLLAENDKLTknvSRLEA 785
Cdd:PHA02562  169 DKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKydelVEEAKTIKAEIEELT---DELLN 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  786 VFVAPEKHEKELMGLKSNIAELKMQLCELNKKcgegqekirALMSENTSLKKTLSSQYvpaKTHEEVKASLSSTLEKTNR 865
Cdd:PHA02562  246 LVMDIEDPSAALNKLNTAAAKIKSKIEQFQKV---------IKMYEKGGVCPTCTQQI---SEGPDRITKIKDKLKELQH 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  866 ALLDSKKRLDDTSQEFSKLREENEVLrRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIV 945
Cdd:PHA02562  314 SLEKLDTAIDELEEIMDEFNEQSKKL-LELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIV 392

                         250       260
                  ....*....|....*....|.
gi 564364067  946 TLHAEIKAQKKELDTIQECIK 966
Cdd:PHA02562  393 KTKSELVKEKYHRGIVTDLLK 413
Ank_5 pfam13857
Ankyrin repeats (many copies);
74-126 2.96e-04

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 40.02  E-value: 2.96e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 564364067    74 ILTHG-IDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALH 126
Cdd:pfam13857    1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALD 54
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 171-249 3.03e-04

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 45.27  E-value: 3.03e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564364067  171 QLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLTLLDALGHDSSYYARIGDNLDILNLLKTASESTSKG 249
Cdd:PTZ00322   99 RILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLSRHSQCHFEL 177
Ank_5 pfam13857
Ankyrin repeats (many copies);
107-161 3.47e-04

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 40.02  E-value: 3.47e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 564364067   107 LLQY-NCPTEHVDLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLA 161
Cdd:pfam13857    1 LLEHgPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
Ank_5 pfam13857
Ankyrin repeats (many copies);
40-95 3.47e-04

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 40.02  E-value: 3.47e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 564364067    40 ILAKKGVHPGKLDVEGRSAFHVVAAKGNLECLNAILTHGIDVATRDSAGRNALHLA 95
Cdd:pfam13857    1 LLEHGPIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTALDLA 56
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 973-1286 3.64e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 44.89  E-value: 3.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   973 SRMEECERkfkatekalkeQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDRnvlVEEAREAERALSRKTEEL 1052
Cdd:pfam07888   34 NRLEECLQ-----------ERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESR---VAELKEELRQSREKHEEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1053 GKQLKELSQKYSDVKSEREKLVEEKAKQTSEILaaqNLLQKQPVPLEQVEALKTSLngtiEHLKEELRSKERCLEREQQA 1132
Cdd:pfam07888  100 EEKYKELSASSEELSEEKDALLAQRAAHEARIR---ELEEDIKTLTQRVLERETEL----ERMKERAKKAGAQRKEEEAE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1133 VSQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSK 1212
Cdd:pfam07888  173 RKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERK 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1213 YKATKNDLETQISNLNDKLASLNRKYDQVC--------------EEKVSAKDEKELLHLNIEQEirdqKERCDKSLTTIM 1278
Cdd:pfam07888  253 VEGLGEELSSMAAQRDRTQAELHQARLQAAqltlqladaslalrEGRARWAQERETLQQSAEAD----KDRIEKLSAELQ 328


                   ....*...
gi 564364067  1279 ELQQRIQE 1286
Cdd:pfam07888  329 RLEERLQE 336
Ank_5 pfam13857
Ankyrin repeats (many copies);
173-220 3.68e-04

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 39.64  E-value: 3.68e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 564364067   173 LIDRG-ADVNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLTLLDALG 220
Cdd:pfam13857    1 LLEHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEG 49
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 429-1124 3.68e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.21  E-value: 3.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   429 LKKELEA-MRTFCDSAKQDRLKLQNELAHKVAECKALALECERVkedsDEQIKQLEDAlkDVQKRMYESEgKVKQMQTHF 507
Cdd:pfam12128  284 TSAELNQlLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEAL----EDQHGAFLDA--DIETAAADQE-QLPSWQSEL 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   508 LALKEHLtnEAATGSHRVIEELREQLKDMKGKYEGASAEVGKLRnQIKQSEmlvegfKRDESRLVEENKrLQKECSTCEI 587
Cdd:pfam12128  357 ENLEERL--KALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDK-LAKIRE------ARDRQLAVAEDD-LQALESELRE 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   588 DRERRGRRVTELEGQLKELGAKLALSVPTETFESmksSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQHIR 667
Cdd:pfam12128  427 QLEAGKLEFNEEEYRLKSRLGELKLRLNQATATP---ELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQ 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   668 PEEHEQLRS-RLEQKSGELGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKahDVNVE 746
Cdd:pfam12128  504 ASEALRQASrRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGG--ELNLY 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   747 DLNKKLsdatqryaeKKLEAERLLAENDKLTKNVSRLEavfvapekheKELMGLKSNIAELKMQLCELNKKCGEGQekiR 826
Cdd:pfam12128  582 GVKLDL---------KRIDVPEWAASEEELRERLDKAE----------EALQSAREKQAAAEEQLVQANGELEKAS---R 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   827 ALMSENTSLKKTLSSQYVPAKTHEEVKaslsstlEKTNRALldsKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADy 906
Cdd:pfam12128  640 EETFARTALKNARLDLRRLFDEKQSEK-------DKKNKAL---AERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQ- 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   907 vsLEEHSRKMNMANQSLKEAQDAHTALLadyrqgQEEIVTLHAEIKAQKKELDT------------------IQECIKLK 968
Cdd:pfam12128  709 --KREARTEKQAYWQVVEGALDAQLALL------KAAIAARRSGAKAELKALETwykrdlaslgvdpdviakLKREIRTL 780

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   969 YAPLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKkgkQENERLRKDLAALQKELKDRNVLVEEAREAERalsrk 1048
Cdd:pfam12128  781 ERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIE---RAISELQQQLARLIADTKLRRAKLEMERKASE----- 852

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1049 teelgKQLKELSQKYSDVKSEREKLVEEKAKQTSEilAAQNLLQKQPVPLEQV----EALKTSLNGTIEHLKEELRSKER 1124
Cdd:pfam12128  853 -----KQQVRLSENLRGLRCEMSKLATLKEDANSE--QAQGSIGERLAQLEDLklkrDYLSESVKKYVEHFKNVIADHSG 925
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
869-1172 4.02e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 4.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  869 DSKKRLDDTSQEFSKLREenevLRRNLENVQNQMKAdyvsLEEhsrkmnmanqsLKEAQDAHTALLADYRQGQEEIVTLH 948
Cdd:COG4913   222 DTFEAADALVEHFDDLER----AHEALEDAREQIEL----LEP-----------IRELAERYAAARERLAELEYLRAALR 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  949 AEIKAQKKELdtIQECIKLKYAPLSRMEECERKFKATEKALKEQLSEqtHKGQVRDEevkkGKQENERLRKDLAALQKEL 1028
Cdd:COG4913   283 LWFAQRRLEL--LEAELEELRAELARLEAELERLEARLDALREELDE--LEAQIRGN----GGDRLEQLEREIERLEREL 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1029 KDRnvlveeareaeralSRKTEELGKQLKELsqkysdvksereklvEEKAKQTSEILAAQnllqkqpvpLEQVEALKTSL 1108
Cdd:COG4913   355 EER--------------ERRRARLEALLAAL---------------GLPLPASAEEFAAL---------RAEAAALLEAL 396

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564364067 1109 NGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHL-QLKEALEKEVGIMKASLR 1172
Cdd:COG4913   397 EEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLlALRDALAEALGLDEAELP 461
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 1001-1331 4.34e-04

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 45.04  E-value: 4.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1001 QVRDEEVKKGKQEN-ERLRKDLAALQKELKdrnvLVEEAREAERALSRKT-EELGKQLKELsqKYSDVKsEREKLVEEKA 1078
Cdd:PTZ00108  987 LVRLDLYKKRKEYLlGKLERELARLSNKVR----FIKHVINGELVITNAKkKDLVKELKKL--GYVRFK-DIIKKKSEKI 1059

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1079 KQTSEILAAQNLLQKQPVPLEQVEALK----------TSLNGT-IEHLKEELRSKERclEREQqavsqlqqlLENQKSSS 1147
Cdd:PTZ00108 1060 TAEEEEGAEEDDEADDEDDEEELGAAVsydyllsmpiWSLTKEkVEKLNAELEKKEK--ELEK---------LKNTTPKD 1128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1148 VTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQtevqntKQALKNLETREVVDMSKYKATKNDLETQISNL 1227
Cdd:PTZ00108 1129 MWLEDLDKFEEALEEQEEVEEKEIAKEQRLKSKTKGKASKLR------KPKLKKKEKKKKKSSADKSKKASVVGNSKRVD 1202

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1228 NDKLASLNRKYDQVCEEKVSAKDEKELlhLNIEQEIRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDV-- 1305
Cdd:PTZ00108 1203 SDEKRKLDDKPDNKKSNSSGSDQEDDE--EQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVsa 1280

                         330       340       350
                  ....*....|....*....|....*....|.
gi 564364067 1306 -----ERLKQALNGLSQLTYSSGGPTKRQSQ 1331
Cdd:PTZ00108 1281 vqyspPPPSKRPDGESNGGSKPSSPTKKKVK 1311
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 120-151 4.99e-04

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 38.81  E-value: 4.99e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 564364067   120 QGRTALHDAA-MADCPSSIQLLCDHGASVNAKD 151
Cdd:pfam00023    1 DGNTPLHLAAgRRGNLEIVKLLLSKGADVNARD 33
TRPV cd21882
Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily ...
 66-187 5.18e-04

Transient Receptor Potential channel, Vanilloid subfamily (TRPV); The vanilloid TRP subfamily (TRPV), named after the vanilloid receptor 1 (TRPV1), consists of six members: four thermo-sensing channels (TRPV1, TRPV2, TRPV3, and TRPV4) and two Ca2+ selective channels (TRPV5 and TRPV6). The calcium-selective channels TRPV5 and TRPV6 can be heterotetramers and are important for general Ca2+ homeostasis. All four channels within the TRPV1-4 group show temperature-invoked currents when expressed in heterologous cell systems, ranging from activation at ~25C for TRPV4 to ~52C for TRPV2. The structure of TRPV shows the typical topology features of all Transient Receptor Potential (TRP) ion channel family members, such as six transmembrane regions, a short hydrophobic stretch between transmembrane segments 5 and 6 and large intracellular N- and C-terminal domains. The TRP family consists of membrane proteins that function as ion channels that communicate between the cell and its environment, by a vast array of physical or chemical stimuli, including radiation (in the form of temperature, infrared ,or light) and pressure (osmotic or mechanical). TRP channels are formed by a tetrameric complex of channel subunits. Based on sequence identity, the mammalian TRP channel family is classified into six subfamilies, with significant sequence similarity within the transmembrane domains, but very low similarity in their N- and C-terminal cytoplasmic regions. The six subfamilies are named based on their first member: TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin), and TRPP (polycystic).


Pssm-ID: 411975 [Multi-domain]  Cd Length: 600  Bit Score: 44.49  E-value: 5.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   66 GNLECLNAILTHgiDVATRDSAGRNALHLAAKYGH-------ALCLQKLLQYNCPTEHVD-------LQGRTALHDAAMA 131
Cdd:cd21882     6 GLLECLRWYLTD--SAYQRGATGKTCLHKAALNLNdgvneaiMLLLEAAPDSGNPKELVNapctdefYQGQTALHIAIEN 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564364067  132 DCPSSIQLLCDHGASVNAKDID-------------GRTPLVLATQMCRPTICQLLIDRGADVNSRDKQN 187
Cdd:cd21882    84 RNLNLVRLLVENGADVSARATGrffrkspgnlfyfGELPLSLAACTNQEEIVRLLLENGAQPAALEAQD 152
PRK12704 PRK12704
phosphodiesterase; Provisional
 1054-1213 5.19e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.38  E-value: 5.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1054 KQLKELSQKYSDVKSEREKLVEEKAKQtsEILAAQNLLQKQpvpLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAV 1133
Cdd:PRK12704   31 AKIKEAEEEAKRILEEAKKEAEAIKKE--ALLEAKEEIHKL---RNEFEKELRERRNELQKLEKRLLQKEENLDRKLELL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1134 SQLQQLLENQKSSSvtladhlqlkEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEvQNTKQALKNLETREVVDMSKY 1213
Cdd:PRK12704  106 EKREEELEKKEKEL----------EQKQQELEKKEEELEELIEEQLQELERISGLTAE-EAKEILLEKVEEEARHEAAVL 174
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 104-239 5.52e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 44.18  E-value: 5.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  104 LQKLLQY--NCPTEHVDlQGRTALHDAAMADCPSSIQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGAD-- 179
Cdd:PHA02874   17 IEKIIKNkgNCINISVD-ETTTPLIDAIRSGDAKIVELFIKHGADINHINTKIPHPLLTAIKIGAHDIIKLLIDNGVDts 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  180 ---------------------VNSRDKQNRTALMLGCEYGCRDAVEVLVRNGADLTLLDALGHDSSYYARIGDNLDILNL 238
Cdd:PHA02874   96 ilpipciekdmiktildcgidVNIKDAELKTFLHYAIKKGDLESIKMLFEYGADVNIEDDNGCYPIHIAIKHNFFDIIKL 175


                  .
gi 564364067  239 L 239
Cdd:PHA02874  176 L 176
PRK11281 PRK11281
mechanosensitive channel MscK;
803-1045 5.87e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.52  E-value: 5.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  803 NIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSqyVPAKTHEEVK-ASLSSTLEKTNRALLDSKKRLDDTSQEF 881
Cdd:PRK11281   74 KIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDE--ETRETLSTLSlRQLESRLAQTLDQLQNAQNDLAEYNSQL 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  882 SKLREEnevlrrnLENVQNQMKADYVSLEEhsrkmnmANQSLKEAQDAHTALLADYRQG-QEEIVTLHAEIKAQKKEL-- 958
Cdd:PRK11281  152 VSLQTQ-------PERAQAALYANSQRLQQ-------IRNLLKGGKVGGKALRPSQRVLlQAEQALLNAQNDLQRKSLeg 217

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  959 -DTIQECIKLKY----APLSRMEE---------CERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDL--- 1021
Cdd:PRK11281  218 nTQLQDLLQKQRdyltARIQRLEHqlqllqeaiNSKRLTLSEKTVQEAQSQDEAARIQANPLVAQELEINLQLSQRLlka 297

                         250       260
                  ....*....|....*....|....*....
gi 564364067 1022 -----AALQKELKDRNVLvEEAREAERAL 1045
Cdd:PRK11281  298 teklnTLTQQNLRVKNWL-DRLTQSERNI 325
CagA_N pfam18971
CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ...
 891-1220 6.04e-04

CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.


Pssm-ID: 408741 [Multi-domain]  Cd Length: 876  Bit Score: 44.38  E-value: 6.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   891 LRRNLENvqnQMKADYVSLEEHSRKMNMANQSLKEAqdAHTALLADYRQGQEEIVTLHAEIKAQKKELdtiqeciklkya 970
Cdd:pfam18971  557 VRRNLEN---KLTAKGLSLQEANKLIKDFLSSNKEL--AGKALNFNKAVAEAKSTGNYDEVKKAQKDL------------ 619

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   971 plsrmEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLrkdlAALQKEL-KDRNVL--VEEAREAERALSR 1047
Cdd:pfam18971  620 -----EKSLRKREHLEKEVEKKLESKSGNKNKMEAKAQANSQKDEIF----ALINKEAnRDARAIayTQNLKGIKRELSD 690

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1048 KTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQPVPLEQVEALKTSLNgtiehlkEELRSKERCLE 1127
Cdd:pfam18971  691 KLEKISKDLKDFSKSFDEFKNGKNKDFSKAEETLKALKGSVKDLGINPEWISKVENLNAALN-------EFKNGKNKDFS 763

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1128 REQQAVSQLQQLLE----NQKSSSVTlaDHLQLKEALEKEVGIMkaslrEKEEESQKKTKEVSKLQTevqnTKQALKNLE 1203
Cdd:pfam18971  764 KVTQAKSDLENSVKdviiNQKVTDKV--DNLNQAVSVAKAMGDF-----SRVEQVLADLKNFSKEQL----AQQAQKNED 832

                          330
                   ....*....|....*..
gi 564364067  1204 TREVVDMSKYKATKNDL 1220
Cdd:pfam18971  833 FNTGKNSELYQSVKNSV 849
46 PHA02562
endonuclease subunit; Provisional
 882-1093 6.37e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 6.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  882 SKLREENE---VLRRNLENVQNQMKAdYVSLEEHSRKMNMANQSlkEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKEL 958
Cdd:PHA02562  174 DKIRELNQqiqTLDMKIDHIQQQIKT-YNKNIEEQRKKNGENIA--RKQNKYDELVEEAKTIKAEIEELTDELLNLVMDI 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  959 DTIQECIK---LKYAPL-SRMEECERKFKATEK-----ALKEQLSEQthkgqvrDEEVKKGKQENERLRKDLAALQKELK 1029
Cdd:PHA02562  251 EDPSAALNklnTAAAKIkSKIEQFQKVIKMYEKggvcpTCTQQISEG-------PDRITKIKDKLKELQHSLEKLDTAID 323

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564364067 1030 DRNVLVEEAREAER---ALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQK 1093
Cdd:PHA02562  324 ELEEIMDEFNEQSKkllELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDK 390
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 662-1207 6.54e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 44.35  E-value: 6.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   662 RAQHIRPEEH-EQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPLRVSEEMKKA 740
Cdd:pfam05557    1 RAELIESKARlSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRL 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   741 HDVNVEDLNKKLSDATQRYAEKKleaERLLAENDKLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGE 820
Cdd:pfam05557   81 KKKYLEALNKKLNEKESQLADAR---EVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQN 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   821 GQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKASLS-----STLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNL 895
Cdd:pfam05557  158 LEKQQSSLAEAEQRIKELEFEIQSQEQDSEIVKNSKSelariPELEKELERLREHNKHLNENIENKLLLKEEVEDLKRKL 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   896 ENvQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQEciKLKYAPLSRM 975
Cdd:pfam05557  238 ER-EEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQREIVLKEENSSLTS--SARQLEKARR 314

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   976 EECERKFKATEKALKEQLSEQTHKGQVRdeevkkgkqeneRLRKDLAALQKELKDRNVLVEE------AREAERALSRKT 1049
Cdd:pfam05557  315 ELEQELAQYLKKIEDLNKKLKRHKALVR------------RLQRRVLLLTKERDGYRAILESydkeltMSNYSPQLLERI 382

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1050 EELGKQLKELSQKYSDVKSEREKLVEEKAKQTS---------EILAAQNLLQKQPVPLEQVEALKTSLNgTIEHLKEELR 1120
Cdd:pfam05557  383 EEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQqaqtlerelQALRQQESLADPSYSKEEVDSLRRKLE-TLELERQRLR 461

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1121 SKERCLEREQqAVSQLQQLLENQKSSSVTLADHLQLK---------EALEKEVGIMKASLREKEEESQK----------- 1180
Cdd:pfam05557  462 EQKNELEMEL-ERRCLQGDYDPKKTKVLHLSMNPAAEayqqrknqlEKLQAEIERLKRLLKKLEDDLEQvlrlpettstm 540

                          570       580
                   ....*....|....*....|....*..
gi 564364067  1181 KTKEVSKLQTEVQNTKqaLKNLETREV 1207
Cdd:pfam05557  541 NFKEVLDLRKELESAE--LKNQRLKEV 565
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
674-901 6.61e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 6.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  674 LRSRLEQKSGELGKKVTELTLKNQTLQKEVEKlyADNKLlnqqvhsltVEMKTRYVPLRVSEEMKKAHDvNVEDLNKKLS 753
Cdd:COG3206   162 LEQNLELRREEARKALEFLEEQLPELRKELEE--AEAAL---------EEFRQKNGLVDLSEEAKLLLQ-QLSELESQLA 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  754 DATQRYAEKKLEAERLlaeNDKLTKNVSRLEAVFVAPEkhekeLMGLKSNIAELKMQLCELNKKCGEGQEKIRALMSENT 833
Cdd:COG3206   230 EARAELAEAEARLAAL---RAQLGSGPDALPELLQSPV-----IQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIA 301

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564364067  834 SLKKTLSSQyvPAKTHEEVKASLSStLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQ 901
Cdd:COG3206   302 ALRAQLQQE--AQRILASLEAELEA-LQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVAREL 366
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
469-680 6.61e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.24  E-value: 6.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  469 ERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQthflalKEHL---TNEAATGSHRVIEELREQLKDMKGKYEGASA 545
Cdd:COG3206   167 ELRREEARKALEFLEEQLPELRKELEEAEAALEEFR------QKNGlvdLSEEAKLLLQQLSELESQLAEARAELAEAEA 240

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  546 EVGKLRNQIKQSEMLVEGFKRDE--SRLVEENKRLQKecstcEIDRERRG------------RRVTELEGQLKELGAKLA 611
Cdd:COG3206   241 RLAALRAQLGSGPDALPELLQSPviQQLRAQLAELEA-----ELAELSARytpnhpdvialrAQIAALRAQLQQEAQRIL 315

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564364067  612 LSVPTE--TFESMKSSLSNDISEKAKRLAEVGRDyessQGEIRQLKRDLESVRAQhirpeeHEQLRSRLEQ 680
Cdd:COG3206   316 ASLEAEleALQAREASLQAQLAQLEARLAELPEL----EAELRRLEREVEVAREL------YESLLQRLEE 376
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 292-611 7.63e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 7.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  292 DLKEKLRKIQQEQRILldKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEESLRTIEALKNRFKyfesdhpgpg 371
Cdd:COG1196   217 ELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE---------- 284

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  372 syssnrkedmlHKQGQMYTADSQctspgvppHMQSRSMLRPLELslpsqtsysENEILKKELEAMRTFCDSAKQDRLKLQ 451
Cdd:COG1196   285 -----------EAQAEEYELLAE--------LARLEQDIARLEE---------RRRELEERLEELEEELAELEEELEELE 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  452 NELAHKVAECKALALEcervKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTNEAATgshrvIEELRE 531
Cdd:COG1196   337 EELEELEEELEEAEEE----LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ-----LEELEE 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  532 QLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVTELEGQLKELGAKLA 611
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA 487
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 459-1237 8.04e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 8.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   459 AECKALALECERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQ-THFLALKEHLTNEAATGSHRVIEELREQLKdmk 537
Cdd:TIGR00618  194 GKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQqSHAYLTQKREAQEEQLKKQQLLKQLRARIE--- 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   538 gKYEGASAEVGKLRNQIKQSemlvegfkRDESRLVEENKRLQKecstCEIDRERRGRRVTELEGQLKELGAKLALSVPTE 617
Cdd:TIGR00618  271 -ELRAQEAVLEETQERINRA--------RKAAPLAAHIKAVTQ----IEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQ 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   618 TFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQhirpeehEQLRSRLEQKSGELGKKvtelTLKNQ 697
Cdd:TIGR00618  338 SSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTL-------QQQKTTLTQKLQSLCKE----LDILQ 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   698 TLQKEVEKLYADNKLLNQQVhsltVEMKTRYVPLRVSEEMKKAHDVNVEDLNKKLSDATQRYAEKKLEAERLLAENDKLT 777
Cdd:TIGR00618  407 REQATIDTRTSAFRDLQGQL----AHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIH 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   778 KNVSRLEAVfvapekHEKELMglksniaELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKASLS 857
Cdd:TIGR00618  483 LQETRKKAV------VLARLL-------ELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYH 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   858 STLEKTNRALLDSKK--RLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKeaqdahtalla 935
Cdd:TIGR00618  550 QLTSERKQRASLKEQmqEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALL----------- 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   936 dyRQGQEEIVTLHAEIKAQKkeldtIQECIKLKYAPLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEvkkgkQENE 1015
Cdd:TIGR00618  619 --RKLQPEQDLQDVRLHLQQ-----CSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLAL-----QKMQ 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1016 RLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNLLQKQP 1095
Cdd:TIGR00618  687 SEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNN 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1096 VPLEQVEalktslngtiEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEvgimkaSLREKE 1175
Cdd:TIGR00618  767 NEEVTAA----------LQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCE------TLVQEE 830

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564364067  1176 EESQKKTKEVSKLQTEVqntKQALKNLEtrevvDMSKYKATKNDLETQISNLNDKLASLNRK 1237
Cdd:TIGR00618  831 EQFLSRLEEKSATLGEI---THQLLKYE-----ECSKQLAQLTQEQAKIIQLSDKLNGINQI 884
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
286-709 1.02e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  286 LEMENEDLKEKLRKIQQEQRILLDKVNGLQLQLneevmvaDDLESEREKLKSLlaakEKQHEESLRTIEALKNRFKYFEs 365
Cdd:PRK03918  298 LSEFYEEYLDELREIEKRLSRLEEEINGIEERI-------KELEEKEERLEEL----KKKLKELEKRLEELEERHELYE- 365

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  366 dhpgpgsyssnrkeDMLHKQGQM--YTADSQCTSPGvpphmQSRSMLRPLElslpsqTSYSENEILKKELEAMRTFCDSA 443
Cdd:PRK03918  366 --------------EAKAKKEELerLKKRLTGLTPE-----KLEKELEELE------KAKEEIEEEISKITARIGELKKE 420

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  444 KQDRLKLQNELAHKVAEC------------KALALECERVKEDSDEQIKQLEDALKDVQKRMYESEG---------KVKQ 502
Cdd:PRK03918  421 IKELKKAIEELKKAKGKCpvcgrelteehrKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKvlkkeseliKLKE 500

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  503 MQTHFLALKEHLTN---EAATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQ 579
Cdd:PRK03918  501 LAEQLKELEEKLKKynlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELE 580

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  580 KECSTCEIDRErrgRRVTELEGQLKE-LGAKLALSVPTETFESMKsSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDL 658
Cdd:PRK03918  581 ELGFESVEELE---ERLKELEPFYNEyLELKDAEKELEREEKELK-KLEEELDKAFEELAETEKRLEELRKELEELEKKY 656

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 564364067  659 EsvraqhirPEEHEQLRSRLEQKSGELGKKVTEL-TLKN--QTLQKEVEKLYAD 709
Cdd:PRK03918  657 S--------EEEYEELREEYLELSRELAGLRAELeELEKrrEEIKKTLEKLKEE 702
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 285-1027 1.05e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.88  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   285 DLEMENEDLKEKLRKIQQEQRILLDKVNGLQLQLN--EEVMVADDLESEREKLKSLLAAKEKQHEESLRTIEALKNRFKY 362
Cdd:TIGR00606  323 DCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADrhQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIER 402

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   363 FESDHPGPGSYSSNRKEDMLHKQGQMYTADSQCTSPGVPPHMQSRSMLRPLE-----LSLPSQTSYSENEILKKELEAMR 437
Cdd:TIGR00606  403 QEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEelkfvIKELQQLEGSSDRILELDQELRK 482

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   438 TFCDSAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLE---DALKDVQKRMYESEGKVKQMQTHFLALKEHL 514
Cdd:TIGR00606  483 AERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNhhtTTRTQMEMLTKDKMDKDEQIRKIKSRHSDEL 562

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   515 TNEAatGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKE------CSTCEID 588
Cdd:TIGR00606  563 TSLL--GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEESD 640

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   589 RERRGRRVTELEGQLKELGAKLALSvptetfesmkSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLES-VRAQHIR 667
Cdd:TIGR00606  641 LERLKEEIEKSSKQRAMLAGATAVY----------SQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSkLRLAPDK 710

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   668 PEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVHSLTVEMKTRYVPL-RVSEEMKKAHDVN-- 744
Cdd:TIGR00606  711 LKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLgTIMPEEESAKVCLtd 790

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   745 ---VEDLNKKLSDATQRYAEkkleaerLLAENDKLTKNVSRLEAVFVAPEKHEkELMGLKSNIAELKMQLCELNKKCGEG 821
Cdd:TIGR00606  791 vtiMERFQMELKDVERKIAQ-------QAAKLQGSDLDRTVQQVNQEKQEKQH-ELDTVVSKIELNRKLIQDQQEQIQHL 862

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   822 QEKIRALMSENTSLKKTLSSqyvpAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVL--RRNLENVQ 899
Cdd:TIGR00606  863 KSKTNELKSEKLQIGTNLQR----RQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELisSKETSNKK 938

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   900 NQMKADYVSlEEHSRKMNMANQSLKEAQDAHTALLadyRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECE 979
Cdd:TIGR00606  939 AQDKVNDIK-EKVKNIHGYMKDIENKIQDGKDDYL---KQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQE 1014

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 564364067   980 RKFK--ATEKALKEQLSE-----QTHKGQVRDEEVKKGKQENERLRKDLAALQKE 1027
Cdd:TIGR00606 1015 RWLQdnLTLRKRENELKEveeelKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRN 1069
PHA02798 PHA02798
ankyrin-like protein; Provisional
 137-213 1.23e-03

ankyrin-like protein; Provisional


Pssm-ID: 222931 [Multi-domain]  Cd Length: 489  Bit Score: 43.28  E-value: 1.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  137 IQLLCDHGASVNAKDIDGRTPL--VLATQ-MCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCR---DAVEVLVRNG 210
Cdd:PHA02798   92 VKILIENGADINKKNSDGETPLycLLSNGyINNLEILLFMIENGADTTLLDKDGFTMLQVYLQSNHHidiEIIKLLLEKG 171


                  ...
gi 564364067  211 ADL 213
Cdd:PHA02798  172 VDI 174
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
453-831 1.42e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.11  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  453 ELAHKVAECKALALECERVKEDSDEQIKQLEDALKDVQKRMyesegkvkqmqTHFLALKEHLTNEAATGSHRvIEELREQ 532
Cdd:PRK02224  255 TLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEER-----------DDLLAEAGLDDADAEAVEAR-REELEDR 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  533 LKDMKGKYEGASAEVGKLRNQIkqsEMLVEGFKRDESR---LVEENKRLQKECSTCEIDRERRGRRVTELEGQLKELGAK 609
Cdd:PRK02224  323 DEELRDRLEECRVAAQAHNEEA---ESLREDADDLEERaeeLREEAAELESELEEAREAVEDRREEIEELEEEIEELRER 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  610 LA-LSVPTETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLE-------------SVRAQHI-----RPEE 670
Cdd:PRK02224  400 FGdAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEagkcpecgqpvegSPHVETIeedreRVEE 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  671 HEQLRSRLEQKSGELGKKVTELTlKNQTLQKEVEKLYADNKLLNQQV--HSLTVEMKTryvpLRVSEEMKKAHDVNVEDL 748
Cdd:PRK02224  480 LEAELEDLEEEVEEVEERLERAE-DLVEAEDRIERLEERREDLEELIaeRRETIEEKR----ERAEELRERAAELEAEAE 554

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  749 NKKLSDATQR-YAEKKLEA----ERLLAENDKLTKNVSRLEAVFVAPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQE 823
Cdd:PRK02224  555 EKREAAAEAEeEAEEAREEvaelNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRE 634


                  ....*...
gi 564364067  824 KIRALMSE 831
Cdd:PRK02224  635 RKRELEAE 642
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
510-1076 1.46e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 43.11  E-value: 1.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  510 LKEHLTNEAATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGF--KRDE-SRLVEENKRLQKECSTCE 586
Cdd:PRK02224  192 LKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHeeRREElETLEAEIEDLRETIAETE 271

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  587 IDRERRGRRVTELEGQLKELGAKLALSVPTETFESMK-SSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAqh 665
Cdd:PRK02224  272 REREELAEEVRDLRERLEELEEERDDLLAEAGLDDADaEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLRE-- 349

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  666 iRPEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVHSLTVEmktryvpLRVSEEMKKAHDVNV 745
Cdd:PRK02224  350 -DADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVD-------LGNAEDFLEELREER 421

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  746 EDLNKKLSD--ATQRYAEKKL-EAERLLAEND--------KLTKNVSRLEAVFVAPEKHEKELmglksniAELKMQLCEL 814
Cdd:PRK02224  422 DELREREAEleATLRTARERVeEAEALLEAGKcpecgqpvEGSPHVETIEEDRERVEELEAEL-------EDLEEEVEEV 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  815 NKKCgEGQEKIRALMSENTSLKKTlssqyvpAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRN 894
Cdd:PRK02224  495 EERL-ERAEDLVEAEDRIERLEER-------REDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEE 566

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  895 LENVQNQMKAdyvsleehsrkMNMANQSLKEAQDAhtalLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLS- 973
Cdd:PRK02224  567 AEEAREEVAE-----------LNSKLAELKERIES----LERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAe 631

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  974 ---RMEECERKFK--ATEKALKEQLSEQTHKGQVrDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEaREAERALSRK 1048
Cdd:PRK02224  632 kreRKRELEAEFDeaRIEEAREDKERAEEYLEQV-EEKLDELREERDDLQAEIGAVENELEELEELRER-REALENRVEA 709

                         570       580
                  ....*....|....*....|....*....
gi 564364067 1049 TEELGKQLKELSQKYSDVKSE-REKLVEE 1076
Cdd:PRK02224  710 LEALYDEAEELESMYGDLRAElRQRNVET 738
PTZ00322 PTZ00322
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
 62-162 1.49e-03

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional


Pssm-ID: 140343 [Multi-domain]  Cd Length: 664  Bit Score: 42.96  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   62 VAAKGNLECLNAILTHGIDVATRDSAGRNALHLAAKYGHALCLQKLLQYNCPTEHVDLQGRTALHDAAMADCPSSIQLL- 140
Cdd:PTZ00322   89 LAASGDAVGARILLTGGADPNCRDYDGRTPLHIACANGHVQVVRVLLEFGADPTLLDKDGKTPLELAEENGFREVVQLLs 168

                          90       100
                  ....*....|....*....|....*...
gi 564364067  141 ----CDHGASVNAK--DIDGRTPLVLAT 162
Cdd:PTZ00322  169 rhsqCHFELGANAKpdSFTGKPPSLEDS 196
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
674-1164 1.61e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  674 LRSRLEQKSGELGKKVTELTLKNqtlQKEVEKLYADNKLLNQQVHSLtvemktryvplrvseemkkahdvnvEDLNKKLS 753
Cdd:COG4717    47 LLERLEKEADELFKPQGRKPELN---LKELKELEEELKEAEEKEEEY-------------------------AELQEELE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  754 DATQRYAEKKLEAERLLAENDKLTKNVSRLEAvFVAPEKHEKELMGLKSNIAELKMQLCElnkkcgegqekIRALMSENT 833
Cdd:COG4717    99 ELEEELEELEAELEELREELEKLEKLLQLLPL-YQELEALEAELAELPERLEELEERLEE-----------LRELEEELE 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  834 SLKKTLssqyvpAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLEEHS 913
Cdd:COG4717   167 ELEAEL------AELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  914 rkmnmANQSLKEAQDAHTALLAdyrqgqeeIVTLHAEIKAQKKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQL 993
Cdd:COG4717   241 -----LEERLKEARLLLLIAAA--------LLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEEL 307

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  994 SEQTHKGQVRDEEVKKGKQE----NERLRKDLAALQKELKDRNVLVEEAREAERALsrKTEELGKQLKELSQKYsDVKSE 1069
Cdd:COG4717   308 QALPALEELEEEELEELLAAlglpPDLSPEELLELLDRIEELQELLREAEELEEEL--QLEELEQEIAALLAEA-GVEDE 384

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1070 RE-----KLVEEKAKQTSEILAAQNLLQKQPVPLEQVEAL--KTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLEn 1142
Cdd:COG4717   385 EElraalEQAEEYQELKEELEELEEQLEELLGELEELLEAldEEELEEELEELEEELEELEEELEELREELAELEAELE- 463

                         490       500
                  ....*....|....*....|..
gi 564364067 1143 QKSSSVTLADHLQLKEALEKEV 1164
Cdd:COG4717   464 QLEEDGELAELLQELEELKAEL 485
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 427-1207 1.66e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 1.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   427 EILKKELEAMRTFCDSAKQDRLKLQNELAHKVAECKALAleceRVKEDSDEQIKQLEDALKDVQKRMYESE-------GK 499
Cdd:pfam01576  359 EELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQ----QAKQDSEHKRKKLEGQLQELQARLSESErqraelaEK 434

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   500 VKQMQTHFLALKeHLTNEAATGSHRVIEE---LREQLKDMKGKYEGASAEVGKLRNQIKQSEmlvegfkrdesrlvEENK 576
Cdd:pfam01576  435 LSKLQSELESVS-SLLNEAEGKNIKLSKDvssLESQLQDTQELLQEETRQKLNLSTRLRQLE--------------DERN 499

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   577 RLQKECSTCEIDRERRGRRVTELEGQLKELGAKL-ALSVPTETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLK 655
Cdd:pfam01576  500 SLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLeEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQ 579

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   656 RDLE--SVRAQHIRpeeheQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKLYADNKLLNQQVHSLTvemktryvplRV 733
Cdd:pfam01576  580 QELDdlLVDLDHQR-----QLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLA----------RA 644

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   734 SEEMKKAHDvNVEDLNKKLsdatqryaekKLEAERLLAENDKLTKNVSRLEavfvapekheKELMGLKSNIAELKMQLCE 813
Cdd:pfam01576  645 LEEALEAKE-ELERTNKQL----------RAEMEDLVSSKDDVGKNVHELE----------RSKRALEQQVEEMKTQLEE 703

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   814 LNKKCGEGqEKIRALMSENTSLKKTLSSQYVPAKTH--EEVKASLSSTL---------EKTNRAL-LDSKKRLDDTSQEF 881
Cdd:pfam01576  704 LEDELQAT-EDAKLRLEVNMQALKAQFERDLQARDEqgEEKRRQLVKQVreleaeledERKQRAQaVAAKKKLELDLKEL 782

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   882 -------SKLREEnevLRRNLENVQNQMKADYVSLEEHSRKMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQ 954
Cdd:pfam01576  783 eaqidaaNKGREE---AVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQA 859

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   955 KKELDTIQECIKLKYAPLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAalqkelkdrnvl 1034
Cdd:pfam01576  860 QQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELA------------ 927

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1035 veeareAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTseilaaqnllqkqpvpleqVEALKTSLNGTIEH 1114
Cdd:pfam01576  928 ------AERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSS-------------------IAALEAKIAQLEEQ 982

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1115 LKEELRSKERCLEREQQAVSQLQQLLEnQKSSSVTLADhlQLKEALEKEVGIMKA---SLREKEEESQKKTKEVSKLQTE 1191
Cdd:pfam01576  983 LEQESRERQAANKLVRRTEKKLKEVLL-QVEDERRHAD--QYKDQAEKGNSRMKQlkrQLEEAEEEASRANAARRKLQRE 1059

                          810
                   ....*....|....*.
gi 564364067  1192 VQNTKQALKNLeTREV 1207
Cdd:pfam01576 1060 LDDATESNESM-NREV 1074
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1004-1217 1.68e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 1.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1004 DEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQ--- 1080
Cdd:COG3883    22 QKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSggs 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1081 ---TSEILAAQN---LLQKQPVpLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHL 1154
Cdd:COG3883   102 vsyLDVLLGSESfsdFLDRLSA-LSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQ 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564364067 1155 Q-LKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATK 1217
Cdd:COG3883   181 EaLLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 244
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1017-1255 1.87e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 1.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1017 LRKDLAALQKELKDRNVL-VEEAREAERALsrKTEELGKQLKELSQKYSDVKSEREKL-VEEKAKQTSEILAAQNLLQKQ 1094
Cdd:PRK05771   14 LKSYKDEVLEALHELGVVhIEDLKEELSNE--RLRKLRSLLTKLSEALDKLRSYLPKLnPLREEKKKVSVKSLEELIKDV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1095 PVPLEQVEALKTSLNGTIEHLKEELRSkercLEREQQAVSQLQQL---LENQKSSSVTLADHLQLKEALEKEVGImKASL 1171
Cdd:PRK05771   92 EEELEKIEKEIKELEEEISELENEIKE----LEQEIERLEPWGNFdldLSLLLGFKYVSVFVGTVPEDKLEELKL-ESDV 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1172 REKEEESQKKTKE-----VSKLQTEVQNT---KQALKNLETREVVD----MSKYKATKNDLETQISNLNDKLASLNRKYD 1239
Cdd:PRK05771  167 ENVEYISTDKGYVyvvvvVLKELSDEVEEelkKLGFERLELEEEGTpselIREIKEELEEIEKERESLLEELKELAKKYL 246

                         250       260
                  ....*....|....*....|
gi 564364067 1240 Q---VCEEKVSA-KDEKELL 1255
Cdd:PRK05771  247 EellALYEYLEIeLERAEAL 266
CCDC22 pfam05667
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ...
 977-1316 1.92e-03

Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.


Pssm-ID: 461708 [Multi-domain]  Cd Length: 600  Bit Score: 42.71  E-value: 1.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   977 ECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQEneRLRKDLAA-LQKELKDRNvlveearEAERALSRKTEELGKQ 1055
Cdd:pfam05667  210 ERNAAELAAAQEWEEEWNSQGLASRLTPEEYRKRKRT--KLLKRIAEqLRSAALAGT-------EATSGASRSAQDLAEL 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1056 LKELSQKY--SDVKSEREKLVEEKAKQ-TSEILAAQNLLQKQPVPLEQV----EALKTSLNGTIEHLKEELRSKERCLER 1128
Cdd:pfam05667  281 LSSFSGSSttDTGLTKGSRFTHTEKLQfTNEAPAATSSPPTKVETEEELqqqrEEELEELQEQLEDLESSIQELEKEIKK 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1129 EQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEvgimkasLREKEEEsqkktkeVSKLQTEVQNTKQALKNL----ET 1204
Cdd:pfam05667  361 LESSIKQVEEELEELKEQNEELEKQYKVKKKTLDL-------LPDAEEN-------IAKLQALVDASAQRLVELagqwEK 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1205 REVVDMSKY---KATKNDLETQISNLNDKLASLNRKYDQVCEEkVSAKDE--KELLhlnieqeirDQKERCDKSlTTIME 1279
Cdd:pfam05667  427 HRVPLIEEYralKEAKSNKEDESQRKLEEIKELREKIKEVAEE-AKQKEElyKQLV---------AEYERLPKD-VSRSA 495

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 564364067  1280 LQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLS 1316
Cdd:pfam05667  496 YTRRILEIVKNIKKQKEEITKILSDTKSLQKEINSLT 532
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1183-1313 1.98e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 1.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1183 KEVSKLQTEVQNTKQALKNLETRevvdMSKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKELLHLniEQE 1262
Cdd:COG1579    24 HRLKELPAELAELEDELAALEAR----LEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYEAL--QKE 97

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 564364067 1263 IRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALN 1313
Cdd:COG1579    98 IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELD 148
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1130-1312 2.00e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 2.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1130 QQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLetreVVD 1209
Cdd:COG3883    19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGER----ARA 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1210 MSKYKATKNDLE-----TQISNLNDKLASLNRkydqvceekVSAKDEKELLHLN-IEQEIRDQKERCDKSLTTIMELQQR 1283
Cdd:COG3883    95 LYRSGGSVSYLDvllgsESFSDFLDRLSALSK---------IADADADLLEELKaDKAELEAKKAELEAKLAELEALKAE 165

                         170       180
                  ....*....|....*....|....*....
gi 564364067 1284 IQESAKQIEAKDNKITELLNDVERLKQAL 1312
Cdd:COG3883   166 LEAAKAELEAQQAEQEALLAQLSAEEAAA 194
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 274-1115 2.74e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 42.35  E-value: 2.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   274 KSNQREHHSFQDLEMENEDLK------EKLRKIQQEQRILLDKVNGlqlqlNEEVMVADDL--ESEREKLKSLLAAKEKQ 345
Cdd:TIGR01612  904 KSIEEEYQNINTLKKVDEYIKicentkESIEKFHNKQNILKEILNK-----NIDTIKESNLieKSYKDKFDNTLIDKINE 978

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   346 HEE-----SLRTIEALKNRF-KYFESDHPGPGSyssnRKEDMLHKQ------------GQMYTADSQCTSPGVPPHMQSR 407
Cdd:TIGR01612  979 LDKafkdaSLNDYEAKNNELiKYFNDLKANLGK----NKENMLYHQfdekekatndieQKIEDANKNIPNIEIAIHTSIY 1054

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   408 SMLRPLELSLPSQTSYSENEILKKELEAMRTFcdSAKQDRLKLQNELAHKVAECKALALECERVKED---SDEQIKQLED 484
Cdd:TIGR01612 1055 NIIDEIEKEIGKNIELLNKEILEEAEINITNF--NEIKEKLKHYNFDDFGKEENIKYADEINKIKDDiknLDQKIDHHIK 1132

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   485 ALKDVQKRmyeSEGKVKQMQTHFLALKE----HLTNEAATGSHRVIEELREQLKDMKGKYEgasaEVGKLRNQIKQSEml 560
Cdd:TIGR01612 1133 ALEEIKKK---SENYIDEIKAQINDLEDvadkAISNDDPEEIEKKIENIVTKIDKKKNIYD----EIKKLLNEIAEIE-- 1203

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   561 vegfkRDESRLVEE---NKRLQKECSTC---EIDRERRGRR--VTELEGQLKELgaklalsvptetfesmksslsNDISE 632
Cdd:TIGR01612 1204 -----KDKTSLEEVkgiNLSYGKNLGKLfleKIDEEKKKSEhmIKAMEAYIEDL---------------------DEIKE 1257

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   633 KAKRLAEVGRDYESSQGEIRQLKRDLESVRAQHIRPEEHEQLRSRLEQKSGELGKKVTELTLKNQtLQKEVEKLYADNKL 712
Cdd:TIGR01612 1258 KSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIEDFSEESDIND-IKKELQKNLLDAQK 1336

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   713 LNQQVHSLTVEMKTRYVPLRVSEEMK-----KAHDVNVEDLNKKLSDATQRyAEKKLEAerlLAENDKLTKNVSRLEAVF 787
Cdd:TIGR01612 1337 HNSDINLYLNEIANIYNILKLNKIKKiidevKEYTKEIEENNKNIKDELDK-SEKLIKK---IKDDINLEECKSKIESTL 1412

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   788 vapekHEKELMGLKSNIAELKMQLC--ELN-----KKCGEGQEKIrALMSENTSLKKTlSSQYVPAKTHEEVKASLSSTL 860
Cdd:TIGR01612 1413 -----DDKDIDECIKKIKELKNHILseESNidtyfKNADENNENV-LLLFKNIEMADN-KSQHILKIKKDNATNDHDFNI 1485

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   861 EKTnRALLDSKKRLDDTSQEFSKLREENEVLRRNLENVQNQMKADYVSLE---EHSRKMNMANQSLKEAQDAHTAllady 937
Cdd:TIGR01612 1486 NEL-KEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAiknKFAKTKKDSEIIIKEIKDAHKK----- 1559

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   938 rqgqeeiVTLHAEIKAQKKEldtiqeciKLKYAPLSRMEECERKFKATEKALKEQLS-EQTHKGQVRDEEVKKGK----Q 1012
Cdd:TIGR01612 1560 -------FILEAEKSEQKIK--------EIKKEKFRIEDDAAKNDKSNKAAIDIQLSlENFENKFLKISDIKKKIndclK 1624

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1013 ENERLRKDLAAL-----QKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLveEKAKQTSEILAA 1087
Cdd:TIGR01612 1625 ETESIEKKISSFsidsqDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDV--DQHKKNYEIGII 1702

                          890       900
                   ....*....|....*....|....*...
gi 564364067  1088 QNLLQKQPVPLEQVEALKTSLNGTIEHL 1115
Cdd:TIGR01612 1703 EKIKEIAIANKEEIESIKELIEPTIENL 1730
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 861-1109 3.20e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.84  E-value: 3.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  861 EKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLENvqnQMKADYVSLEEhsrkmnmanqSLKEAQDAHTALLADYRQG 940
Cdd:PRK05771   39 ELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREE---KKKVSVKSLEE----------LIKDVEEELEKIEKEIKEL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  941 QEEIVTLHAEIKAQKKEldtIQECIKLKYAPLSrmEECERKFKATE-------KALKEQLSEQTHKGQVRDEEVKKGK-- 1011
Cdd:PRK05771  106 EEEISELENEIKELEQE---IERLEPWGNFDLD--LSLLLGFKYVSvfvgtvpEDKLEELKLESDVENVEYISTDKGYvy 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1012 ----------QENERLRKDLAALQKELKDRNVLVEEAREAERALS---RKTEELGKQLKELSQKYSD-VKSEREKL--VE 1075
Cdd:PRK05771  181 vvvvvlkelsDEVEEELKKLGFERLELEEEGTPSELIREIKEELEeieKERESLLEELKELAKKYLEeLLALYEYLeiEL 260

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 564364067 1076 EKAKQTSEILAAQNLLQKQP-VPLEQVEALKTSLN 1109
Cdd:PRK05771  261 ERAEALSKFLKTDKTFAIEGwVPEDRVKKLKELID 295
PHA02946 PHA02946
ankyin-like protein; Provisional
 137-213 3.35e-03

ankyin-like protein; Provisional


Pssm-ID: 165256 [Multi-domain]  Cd Length: 446  Bit Score: 41.58  E-value: 3.35e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564364067  137 IQLLCDHGASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTAL--MLGCEYGCRDAVEVLVRNGADL 213
Cdd:PHA02946   55 VEELLHRGYSPNETDDDGNYPLHIASKINNNRIVAMLLTHGADPNACDKQHKTPLyyLSGTDDEVIERINLLVQYGAKI 133
Ank_3 pfam13606
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 153-181 3.35e-03

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.


Pssm-ID: 463933 [Multi-domain]  Cd Length: 30  Bit Score: 36.47  E-value: 3.35e-03
                           10        20
                   ....*....|....*....|....*....
gi 564364067   153 DGRTPLVLATQMCRPTICQLLIDRGADVN 181
Cdd:pfam13606    1 DGNTPLHLAARNGRLEIVKLLLENGADIN 29
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 1048-1319 3.68e-03

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 42.13  E-value: 3.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1048 KTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTS---EILAAQNLLQKQPVPLEQVEALKTSLNGTIEHLKEeLRSKER 1124
Cdd:PTZ00440  451 KINELKKSINQLKTLISIMKSFYDLIISEKDSMDSkekKESSDSNYQEKVDELLQIINSIKEKNNIVNNNFKN-IEDYYI 529

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1125 CLEREQQAVSQLQQLLENQKSSSVTLADHlqlkealEKEVGIMKASLREK---EEESQKKTKEVSKLQTEVQNTKQALKN 1201
Cdd:PTZ00440  530 TIEGLKNEIEGLIELIKYYLQSIETLIKD-------EKLKRSMKNDIKNKikyIEENVDHIKDIISLNDEIDNIIQQIEE 602

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1202 LETREVVDMSKYKATKNDLETQISNLNDK------------LASLNRKYDQVCEEKVSAKDEKELLHLNIEQEIRDQKER 1269
Cdd:PTZ00440  603 LINEALFNKEKFINEKNDLQEKVKYILNKfykgdlqelldeLSHFLDDHKYLYHEAKSKEDLQTLLNTSKNEYEKLEFMK 682

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 564364067 1270 CDKSLTTIMELQqriQESAKQIEAKDNKITELLNDVErlKQALNGLSQLT 1319
Cdd:PTZ00440  683 SDNIDNIIKNLK---KELQNLLSLKENIIKKQLNNIE--QDISNSLNQYT 727
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 987-1249 3.84e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 41.86  E-value: 3.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  987 KALKEQLSE-QTHKGQVRDEEVKKgKQENERLRKDLAALQKELKDRNVL---------------VEEAREAERALSRKTE 1050
Cdd:COG3096   839 AALRQRRSElERELAQHRAQEQQL-RQQLDQLKEQLQLLNKLLPQANLLadetladrleelreeLDAAQEAQAFIQQHGK 917

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1051 ELGK-------------QLKELSQKYSDVKSEREKLveekaKQTSEILA--AQNLL----QKQPVPLEQVEALKTSLNGT 1111
Cdd:COG3096   918 ALAQleplvavlqsdpeQFEQLQADYLQAKEQQRRL-----KQQIFALSevVQRRPhfsyEDAVGLLGENSDLNEKLRAR 992

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1112 IEHLKEELRSKERCLEREQQAVSQLQQLLENQKSSSVTLADHLQlkeALEKEVGIMkaSLREKEEESQKKTKEVSKLQTE 1191
Cdd:COG3096   993 LEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQ---ELEQELEEL--GVQADAEAEERARIRRDELHEE 1067

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 564364067 1192 VQNTKQALKNLETrevvdmskykaTKNDLETQISNLNDKLASLNRKYDQVCEEKVSAK 1249
Cdd:COG3096  1068 LSQNRSRRSQLEK-----------QLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAK 1114
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
429-833 4.00e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 4.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  429 LKKELEAMRTFCDSAKQDRLKLQNELAHKVAECKALALECERvkEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFL 508
Cdd:COG4717    93 LQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQEL--EALEAELAELPERLEELEERLEELRELEEELEELEA 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  509 ALKEhLTNEAATGSHRVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEmlvegfkrdesrlvEENKRLQKecstcEID 588
Cdd:COG4717   171 ELAE-LQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ--------------EELEELEE-----ELE 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  589 RERRGRRVTELEGQLKELGAKLALSVPTETFESMKSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAQHIRP 668
Cdd:COG4717   231 QLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQAL 310

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  669 EEHEQLRSRleqksgELGKKVTELTLKNQTLQKEVEKLYADN---KLLNQQVHSLTVEMKTRYVPLRVSEEMKKAHDVNV 745
Cdd:COG4717   311 PALEELEEE------ELEELLAALGLPPDLSPEELLELLDRIeelQELLREAEELEEELQLEELEQEIAALLAEAGVEDE 384

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  746 EDLNKKLsDATQRYAEKKLEAERLLAENDKLTKNVSRLEAVFVaPEKHEKELMGLKSNIAELKMQLCELNKKCGEGQEKI 825
Cdd:COG4717   385 EELRAAL-EQAEEYQELKEELEELEEQLEELLGELEELLEALD-EEELEEELEELEEELEELEEELEELREELAELEAEL 462


                  ....*...
gi 564364067  826 RALMSENT 833
Cdd:COG4717   463 EQLEEDGE 470
46 PHA02562
endonuclease subunit; Provisional
 731-1004 4.10e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.54  E-value: 4.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  731 LRVSEEMKKAHDVNVEDLNKKLS--DATQRYAEKKLEA-ERLLAENDKLTK-NVSRLEAVFvapEKHEKELMGLKSNIAE 806
Cdd:PHA02562  162 ISVLSEMDKLNKDKIRELNQQIQtlDMKIDHIQQQIKTyNKNIEEQRKKNGeNIARKQNKY---DELVEEAKTIKAEIEE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  807 LKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEE--VKASLSSTLEKTNRALLDSKKRLDDTSQEFSKL 884
Cdd:PHA02562  239 LTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKggVCPTCTQQISEGPDRITKIKDKLKELQHSLEKL 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  885 REEnevlrrnlenvqnqmkadyvsLEEHSRKMNMANQSLKEAQDahtaLLADYRQGQEEIVTLHAEIKAQKKELDTIQEC 964
Cdd:PHA02562  319 DTA---------------------IDELEEIMDEFNEQSKKLLE----LKNKISTNKQSLITLVDKAKKVKAAIEELQAE 373

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 564364067  965 IKLKYAPLSRMEECERKFKATEKALKEqlsEQTHKGQVRD 1004
Cdd:PHA02562  374 FVDNAEELAKLQDELDKIVKTKSELVK---EKYHRGIVTD 410
PRK11281 PRK11281
mechanosensitive channel MscK;
985-1391 4.31e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 41.82  E-value: 4.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  985 TEKALKEQLseqthkgqvrdEEVKKGKQENErlrkDLAALQKELKDRNVLVEEAREAERalsrKTEELGKQLKELSQKYS 1064
Cdd:PRK11281   37 TEADVQAQL-----------DALNKQKLLEA----EDKLVQQDLEQTLALLDKIDRQKE----ETEQLKQQLAQAPAKLR 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1065 DVKSEREKLVEEKAKQTSEILAAQNLLQKQpvplEQVEALKTSLNGTIEHLKE---ELRSKERCLEREQQAVS----QLQ 1137
Cdd:PRK11281   98 QAQAELEALKDDNDEETRETLSTLSLRQLE----SRLAQTLDQLQNAQNDLAEynsQLVSLQTQPERAQAALYansqRLQ 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1138 Q---LLENQKSSSVTLADHLQLKEALEKevgimkASLREKEEESQKKTKEVSKLQtEVQNTKQALKNLETrevvdmskyk 1214
Cdd:PRK11281  174 QirnLLKGGKVGGKALRPSQRVLLQAEQ------ALLNAQNDLQRKSLEGNTQLQ-DLLQKQRDYLTARI---------- 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1215 atkNDLETQISNLNDklaSLNRKYDQVCEEKVSakdekellhlniEQEIRDQKERCDKSLTTIMELQQRIQESAKQIEAK 1294
Cdd:PRK11281  237 ---QRLEHQLQLLQE---AINSKRLTLSEKTVQ------------EAQSQDEAARIQANPLVAQELEINLQLSQRLLKAT 298

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1295 DnKITELLNDVERLKQALNGLSQltyssggpTKRQ-----SQLVDTL-------QQR--------VRDLQQQLADAdRQH 1354
Cdd:PRK11281  299 E-KLNTLTQQNLRVKNWLDRLTQ--------SERNikeqiSVLKGSLllsrilyQQQqalpsadlIEGLADRIADL-RLE 368

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 564364067 1355 Q-EV---------IAIYRTHLLSAAQGHMDEDVQAALLQIIQMRQGL 1391
Cdd:PRK11281  369 QfEInqqrdalfqPDAYIDKLEAGHKSEVTDEVRDALLQLLDERREL 415
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
501-706 4.63e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 4.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  501 KQMQTHFLALKEHLTNeaATGSHRVIEELREQ------LKDMKGKYEGASAEVGKLRNQIK-----QSEMLVEGFKRDES 569
Cdd:COG4913   221 PDTFEAADALVEHFDD--LERAHEALEDAREQiellepIRELAERYAAARERLAELEYLRAalrlwFAQRRLELLEAELE 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  570 RLVEENKRLQKECSTCEIDRERRGRRVTELEGQLKELGAKLalsvptetfesmKSSLSNDISEKAKRLAEVGRDYESSQG 649
Cdd:COG4913   299 ELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDR------------LEQLEREIERLERELEERERRRARLEA 366

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564364067  650 EIRQLK-------RDLESVRAQ-HIRPEEHEQLRSRLEQKSGELGKKVTELTLKNQTLQKEVEKL 706
Cdd:COG4913   367 LLAALGlplpasaEEFAALRAEaAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASL 431
46 PHA02562
endonuclease subunit; Provisional
 1110-1312 4.74e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.15  E-value: 4.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1110 GTIEHLKEELRSKERCLEREQQAVSQLQQLLENQksssvtLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQ 1189
Cdd:PHA02562  163 SVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQ------IKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEI 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1190 TEVQNtkqALKNLetreVVDMSKYKATKNDLETQISNLNDKLASLNR-----KYDQVCEEKVSAKDEKEllhlNIEQEIR 1264
Cdd:PHA02562  237 EELTD---ELLNL----VMDIEDPSAALNKLNTAAAKIKSKIEQFQKvikmyEKGGVCPTCTQQISEGP----DRITKIK 305

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 564364067 1265 DQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQAL 1312
Cdd:PHA02562  306 DKLKELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSL 353
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1011-1198 4.83e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.35  E-value: 4.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1011 KQENERLRKDLAALQKELKdrnvlvEEAREAERALsRKTEELgkqLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQNl 1090
Cdd:PRK00409  515 KEKLNELIASLEELERELE------QKAEEAEALL-KEAEKL---KEELEEKKEKLQEEEDKLLEEAEKEAQQAIKEAK- 583

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1091 lqkqpvplEQVEALKTSLNGTIEHLKEELRSKErcLEREQQAVSQLQQLLENQKSSSVTLADHLQLK------------E 1158
Cdd:PRK00409  584 --------KEADEIIKELRQLQKGGYASVKAHE--LIEARKRLNKANEKKEKKKKKQKEKQEELKVGdevkylslgqkgE 653

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 564364067 1159 ALEK--------EVGIMKASLREKEEESQKKTKE--VSKLQTEVQNTKQA 1198
Cdd:PRK00409  654 VLSIpddkeaivQAGIMKMKVPLSDLEKIQKPKKkkKKKPKTVKPKPRTV 703
mukB PRK04863
chromosome partition protein MukB;
987-1249 5.51e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.48  E-value: 5.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  987 KALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVL---------------VEEAREAERALSRKtee 1051
Cdd:PRK04863  840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLNLLadetladrveeireqLDEAEEAKRFVQQH--- 916

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1052 lGKQLKELSQKYSDVKSEREKLVEEKAkqtsEILAAQNLLQKQPvplEQVEALkTSLNGTIEHLKEElrSKERCLEREQQ 1131
Cdd:PRK04863  917 -GNALAQLEPIVSVLQSDPEQFEQLKQ----DYQQAQQTQRDAK---QQAFAL-TEVVQRRAHFSYE--DAAEMLAKNSD 985

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1132 AVSQLQQLLENQKsssvtlADHLQLKEALekevgimkaslREKEEESQKKTKEVSKLQTEVQNTKQALKNLEtREVVDM- 1210
Cdd:PRK04863  986 LNEKLRQRLEQAE------QERTRAREQL-----------RQAQAQLAQYNQVLASLKSSYDAKRQMLQELK-QELQDLg 1047

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564364067 1211 ----------------------SKYKATKNDLETQIS-------NLNDKLASLNRKYDQVCEEKVSAK 1249
Cdd:PRK04863 1048 vpadsgaeerararrdelharlSANRSRRNQLEKQLTfceaemdNLTKKLRKLERDYHEMREQVVNAK 1115
Ank_5 pfam13857
Ankyrin repeats (many copies);
142-191 5.52e-03

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 36.56  E-value: 5.52e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 564364067   142 DHG-ASVNAKDIDGRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTAL 191
Cdd:pfam13857    3 EHGpIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAYGVDLNLKDEEGLTAL 53
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1126-1315 5.53e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.20  E-value: 5.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1126 LEREQQAVSQLQQLLENQKSSSVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETR 1205
Cdd:PRK03918  157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1206 EV------VDMSKYKATKNDLETQISNLNDKLASLnRKYDQVCEEKVS-----AKDEKELLHLN-IEQEIRDQKERCDKS 1273
Cdd:PRK03918  237 KEeieeleKELESLEGSKRKLEEKIRELEERIEEL-KKEIEELEEKVKelkelKEKAEEYIKLSeFYEEYLDELREIEKR 315

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 564364067 1274 LTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGL 1315
Cdd:PRK03918  316 LSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL 357
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
987-1271 5.72e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 5.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  987 KALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDV 1066
Cdd:COG4372    41 DKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEEL 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1067 KSEREKLVEEKAKQTSEILAAQNLLQKQpvpleqvEALKTSLNGTIEHLKEELRSKERCLEREQQAvsQLQQLLENQKSS 1146
Cdd:COG4372   121 QKERQDLEQQRKQLEAQIAELQSEIAER-------EEELKELEEQLESLQEELAALEQELQALSEA--EAEQALDELLKE 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1147 SVTLADHLQLKEALEKEVGIMKASLREKEEESQKKTKEVSKLQTEVQNTKQALKNLETREVVDMSKYKATKNDLETQISN 1226
Cdd:COG4372   192 ANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEK 271

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 564364067 1227 LNDKLASLNRKYDQVCEEKVSAKDEKELLHLNIEQEIRDQKERCD 1271
Cdd:COG4372   272 DTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDA 316
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 915-1088 6.00e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.58  E-value: 6.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  915 KMNMANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAplsRMEECERKFKATEKALKEQLS 994
Cdd:COG3883    17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQA---EIAEAEAEIEERREELGERAR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  995 EQTHKGQVRD--------------------------------EEVKKGKQENERLRKDLAALQKELKDrnvLVEEAREAE 1042
Cdd:COG3883    94 ALYRSGGSVSyldvllgsesfsdfldrlsalskiadadadllEELKADKAELEAKKAELEAKLAELEA---LKAELEAAK 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 564364067 1043 RALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTSEILAAQ 1088
Cdd:COG3883   171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAA 216
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1099-1317 6.18e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 6.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1099 EQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQllenqKSSSVTLADHLQLkeaLEKEVGIMKASLREKEEES 1178
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQ-----KNGLVDLSEEAKL---LLQQLSELESQLAEARAEL 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1179 QKKTKEVSKLQTEVQNTKQALKNLETREVVdmSKYKATKNDLETQISNLNDKLASLNRKYDQVCEEKVSAKDEKELLHLN 1258
Cdd:COG3206   236 AEAEARLAALRAQLGSGPDALPELLQSPVI--QQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQR 313

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564364067 1259 IEQEIRDQKERCDKSLTTIMELQQRIQESAKQIEAKDNKITELLNDVERLKQALNGLSQ 1317
Cdd:COG3206   314 ILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQ 372
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 856-1199 6.25e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 40.96  E-value: 6.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   856 LSSTLEKTNRALLDSKKRLDDTSQEFSKLREENEVLRRNLEN-------VQNQMKADYVSLEEHSRKMNMANQSLKEAQD 928
Cdd:pfam10174  294 LKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAkeqraaiLQTEVDALRLRLEEKESFLNKKTKQLQDLTE 373

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   929 AHTALLADYRQGQEEIVTLHAEIKAQKKELDTIQECIKLKYAPLS----RMEECERKFKATEKALK-------------E 991
Cdd:pfam10174  374 EKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAglkeRVKSLQTDSSNTDTALTtleealsekeriiE 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067   992 QLSEQTHK-GQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSER 1070
Cdd:pfam10174  454 RLKEQREReDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAVEQKKEEC 533

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  1071 EKL---------VEEKAKQTSEILAAQNLLQKQpVPLEQVEALKTslNGTIEHLKEELRSKERCLEREQQAVSQLQQLLE 1141
Cdd:pfam10174  534 SKLenqlkkahnAEEAVRTNPEINDRIRLLEQE-VARYKEESGKA--QAEVERLLGILREVENEKNDKDKKIAELESLTL 610

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564364067  1142 NQKSSSVTLADHLQLKEALEKEVGIM---KASLREKEEESQKKTKEVSKLQTEVQNTKQAL 1199
Cdd:pfam10174  611 RQMKEQNKKVANIKHGQQEMKKKGAQlleEARRREDNLADNSQQLQLEELMGALEKTRQEL 671
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1016-1187 6.92e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 6.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1016 RLRKDLAALQKELKDrnvLVEEAREAERALSRKTEELGKQLKELSQKYSDVKSEREKLVEEKAKQTS-----EILAaqnl 1090
Cdd:COG1579    21 RLEHRLKELPAELAE---LEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrnnkEYEA---- 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067 1091 LQKQpvpLEQVEALKTSLNGTIEHLKEELRSKERCLEREQQAVSQLQQLLEnqksssvtladhlQLKEALEKEVGIMKAS 1170
Cdd:COG1579    94 LQKE---IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELE-------------EKKAELDEELAELEAE 157

                         170
                  ....*....|....*..
gi 564364067 1171 LREKEEESQKKTKEVSK 1187
Cdd:COG1579   158 LEELEAEREELAAKIPP 174
46 PHA02562
endonuclease subunit; Provisional
 442-635 6.95e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 40.77  E-value: 6.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  442 SAKQDRLKLQNELAHKVAECKALALECERVKEDSDEQIKQLED---ALKDVQKRMYESEGKVKQMQTHFLALKEHLTNEA 518
Cdd:PHA02562  210 KNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDpsaALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPT 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  519 ATG----SHRVIEELREQLKDMKGKYEGASAEVGKL--------RNQIKQSEML--VEGFKRDESRLVEENKRLQKECST 584
Cdd:PHA02562  290 CTQqiseGPDRITKIKDKLKELQHSLEKLDTAIDELeeimdefnEQSKKLLELKnkISTNKQSLITLVDKAKKVKAAIEE 369

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 564364067  585 CEIDRERRGRRVTELEGQLKELGAKLALSVPTETFESMKSSLSNDISEKAK 635
Cdd:PHA02562  370 LQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHRGIVTDLLKDSGIKAS 420
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
524-716 6.96e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 40.77  E-value: 6.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  524 RVIEELREQLKDMKGKYEGASAEVgklrNQIKQSEMLV---EGFKRDESRLVEENKRLQKEcstcEIDRERRGRRVTELE 600
Cdd:COG3206   175 KALEFLEEQLPELRKELEEAEAAL----EEFRQKNGLVdlsEEAKLLLQQLSELESQLAEA----RAELAEAEARLAALR 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  601 GQLKELGAKLALSVPTETFesmkSSLSNDISEKAKRLAEVGRDYESSQGEIRQLKRDLESVRAqhirpeeheQLRSRLEQ 680
Cdd:COG3206   247 AQLGSGPDALPELLQSPVI----QQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRA---------QLQQEAQR 313

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 564364067  681 KSGELGKKVTELTLKNQTLQKEVEKLYADNKLLNQQ 716
Cdd:COG3206   314 ILASLEAELEALQAREASLQAQLAQLEARLAELPEL 349
Ank_4 pfam13637
Ankyrin repeats (many copies);
154-207 7.05e-03

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 36.10  E-value: 7.05e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 564364067   154 GRTPLVLATQMCRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLV 207
Cdd:pfam13637    1 ELTALHAAAASGHLELLRLLLEKGADINAVDGNGETALHFAASNGNVEVLKLLL 54
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
524-606 8.40e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 40.61  E-value: 8.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  524 RVIEELREQLKDMKGKYEGASAEVGKLRNQIK--QSEMLVEGFKRDE-SRLVEENKRLQKecstcEIDRERrgRRVTELE 600
Cdd:COG2433   420 EQVERLEAEVEELEAELEEKDERIERLERELSeaRSEERREIRKDREiSRLDREIERLER-----ELEEER--ERIEELK 492


                  ....*.
gi 564364067  601 GQLKEL 606
Cdd:COG2433   493 RKLERL 498
COG4026 COG4026
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ...
 524-600 9.38e-03

Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];


Pssm-ID: 443204 [Multi-domain]  Cd Length: 287  Bit Score: 39.71  E-value: 9.38e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564364067  524 RVIEELREQLKDMKGKYEGASAEVGKLRNQIKQSEMLVEGFKRDESRLVEENKRLQKECSTCEIDRERRGRRVTELE 600
Cdd:COG4026   128 PEYNELREELLELKEKIDEIAKEKEKLTKENEELESELEELREEYKKLREENSILEEEFDNIKSEYSDLKSRFEELL 204
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
800-1080 9.97e-03

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 39.51  E-value: 9.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  800 LKSNIAELKMQLCELNKKCGEGQEKIRALMSENTSLKKTLSSQYVPAKTHEEVKASLSSTLEKTNRALLDSKKRLDDTSQ 879
Cdd:COG1340     6 LSSSLEELEEKIEELREEIEELKEKRDELNEELKELAEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNE 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  880 EFSKLREENEVLRRNLENVqNQMKADYVSLEEhsrkmnmANQSLKEAQDAHTALLADYRQGQEEIVTLHAEIKAQKKELD 959
Cdd:COG1340    86 KLNELREELDELRKELAEL-NKAGGSIDKLRK-------EIERLEWRQQTEVLSPEEEKELVEKIKELEKELEKAKKALE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564364067  960 TIQEciklkyapLSRMEECERKFKATEKALKEQLSEQTHKGQVRDEEVKKGKQENERLRKDLAALQKELKDRNVLVEEAR 1039
Cdd:COG1340   158 KNEK--------LKELRAELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADELH 229

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 564364067 1040 EAERALSRKTEELGKQLKELSQKYSDVKSEREK-LVEEKAKQ 1080
Cdd:COG1340   230 EEIIELQKELRELRKELKKLRKKQRALKREKEKeELEEKAEE 271
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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