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Conserved domains on  [gi|564355627|ref|XP_006240044|]
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B-cell receptor-associated protein 29 isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bap31 pfam05529
Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic ...
 1-129 1.61e-56

Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This family also contains the Bap29 protein that forms a heterodimer with Bap 31.


:

Pssm-ID: 461673  Cd Length: 137  Bit Score: 176.53  E-value: 1.61e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564355627    1 MTIQWAAVASFLYAEIGLILIFCLPFISPQRwHKIFSFSVWTKIASFWNKAFLTIIILLVVLFLDAVREVKKYSSINVVE 80
Cdd:pfam05529   1 MTLQWTLVFGFLYAEMAVFLLLVLPLPSPVR-QKIFKSRSESPLSAKFQIGFKITIIFLLILFLDAVRRVRKYSAELESA 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 564355627   81 KNSASR-PAAYEQAQMRLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAK 129
Cdd:pfam05529  80 KANAHQhPSARMEVQARKFYAQRNLYICGFTLFLSLVLRRTVTLISELAT 129
Bap31_Bap29_C pfam18035
Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the ...
 185-241 4.18e-09

Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This entry represents the cytoplasmic domain which forms a heterodimeric coiled-coil with Bap29. This Bap29 and Bap31 are homologous to each other and this entry includes both proteins.


:

Pssm-ID: 465623 [Multi-domain]  Cd Length: 52  Bit Score: 51.12  E-value: 4.18e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 564355627  185 ERLKTELKKAsdalfkaQNDVMTMKIQSERLSKEYDRLLKEHSELQNRlEKENKKGL 241
Cdd:pfam18035   4 EKLKKELKKK-------KSDIEALKKQAEGLQREYDRLSDEHAKLQLD-EGEDKKDD 52
 
Name Accession Description Interval E-value
Bap31 pfam05529
Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic ...
 1-129 1.61e-56

Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This family also contains the Bap29 protein that forms a heterodimer with Bap 31.


Pssm-ID: 461673  Cd Length: 137  Bit Score: 176.53  E-value: 1.61e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564355627    1 MTIQWAAVASFLYAEIGLILIFCLPFISPQRwHKIFSFSVWTKIASFWNKAFLTIIILLVVLFLDAVREVKKYSSINVVE 80
Cdd:pfam05529   1 MTLQWTLVFGFLYAEMAVFLLLVLPLPSPVR-QKIFKSRSESPLSAKFQIGFKITIIFLLILFLDAVRRVRKYSAELESA 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 564355627   81 KNSASR-PAAYEQAQMRLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAK 129
Cdd:pfam05529  80 KANAHQhPSARMEVQARKFYAQRNLYICGFTLFLSLVLRRTVTLISELAT 129
COG5374 COG5374
Uncharacterized conserved protein [Function unknown];
1-190 2.05e-09

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227666 [Multi-domain]  Cd Length: 192  Bit Score: 55.58  E-value: 2.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564355627   1 MTIQWAAVASFLYAEIGLILIFCLPFisPQRWHKIFsFSVWTKiaSFWNKAFLTII----ILLVVLFLDAVRE---VKKY 73
Cdd:COG5374    1 MGIYYTLVFSLLVVEMVMFFILVLPL--PKRLRRSL-MKLYST--SKVYRGFKHILkitfIFILLLFIDSWKRvyrVSKE 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564355627  74 SSINVVEKNSASrpAAYEQAQMRLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKEITNKGVLKIQAENTNKAAKKFME 153
Cdd:COG5374   76 ANLYSASINNYA--VTRIAVLASRFYAQRNMYLSGSALFLSIVVMRVMSIVEEMLEENAKKGGKIDKMEADSTDLKARLR 153

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 564355627 154 ENERLKLVLKNNDNTEEHVLETENKK--LVEDKERLKTE 190
Cdd:COG5374  154 KAQILLEGLQKNQEELFKLLDKYNELreQVQKESSKKKE 192
Bap31_Bap29_C pfam18035
Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the ...
 185-241 4.18e-09

Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This entry represents the cytoplasmic domain which forms a heterodimeric coiled-coil with Bap29. This Bap29 and Bap31 are homologous to each other and this entry includes both proteins.


Pssm-ID: 465623 [Multi-domain]  Cd Length: 52  Bit Score: 51.12  E-value: 4.18e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 564355627  185 ERLKTELKKAsdalfkaQNDVMTMKIQSERLSKEYDRLLKEHSELQNRlEKENKKGL 241
Cdd:pfam18035   4 EKLKKELKKK-------KSDIEALKKQAEGLQREYDRLSDEHAKLQLD-EGEDKKDD 52
 
Name Accession Description Interval E-value
Bap31 pfam05529
Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic ...
 1-129 1.61e-56

Bap31/Bap29 transmembrane region; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This family also contains the Bap29 protein that forms a heterodimer with Bap 31.


Pssm-ID: 461673  Cd Length: 137  Bit Score: 176.53  E-value: 1.61e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564355627    1 MTIQWAAVASFLYAEIGLILIFCLPFISPQRwHKIFSFSVWTKIASFWNKAFLTIIILLVVLFLDAVREVKKYSSINVVE 80
Cdd:pfam05529   1 MTLQWTLVFGFLYAEMAVFLLLVLPLPSPVR-QKIFKSRSESPLSAKFQIGFKITIIFLLILFLDAVRRVRKYSAELESA 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 564355627   81 KNSASR-PAAYEQAQMRLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAK 129
Cdd:pfam05529  80 KANAHQhPSARMEVQARKFYAQRNLYICGFTLFLSLVLRRTVTLISELAT 129
COG5374 COG5374
Uncharacterized conserved protein [Function unknown];
1-190 2.05e-09

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 227666 [Multi-domain]  Cd Length: 192  Bit Score: 55.58  E-value: 2.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564355627   1 MTIQWAAVASFLYAEIGLILIFCLPFisPQRWHKIFsFSVWTKiaSFWNKAFLTII----ILLVVLFLDAVRE---VKKY 73
Cdd:COG5374    1 MGIYYTLVFSLLVVEMVMFFILVLPL--PKRLRRSL-MKLYST--SKVYRGFKHILkitfIFILLLFIDSWKRvyrVSKE 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564355627  74 SSINVVEKNSASrpAAYEQAQMRLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKEITNKGVLKIQAENTNKAAKKFME 153
Cdd:COG5374   76 ANLYSASINNYA--VTRIAVLASRFYAQRNMYLSGSALFLSIVVMRVMSIVEEMLEENAKKGGKIDKMEADSTDLKARLR 153

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 564355627 154 ENERLKLVLKNNDNTEEHVLETENKK--LVEDKERLKTE 190
Cdd:COG5374  154 KAQILLEGLQKNQEELFKLLDKYNELreQVQKESSKKKE 192
Bap31_Bap29_C pfam18035
Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the ...
 185-241 4.18e-09

Bap31/Bap29 cytoplasmic coiled-coil domain; Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. This entry represents the cytoplasmic domain which forms a heterodimeric coiled-coil with Bap29. This Bap29 and Bap31 are homologous to each other and this entry includes both proteins.


Pssm-ID: 465623 [Multi-domain]  Cd Length: 52  Bit Score: 51.12  E-value: 4.18e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 564355627  185 ERLKTELKKAsdalfkaQNDVMTMKIQSERLSKEYDRLLKEHSELQNRlEKENKKGL 241
Cdd:pfam18035   4 EKLKKELKKK-------KSDIEALKKQAEGLQREYDRLSDEHAKLQLD-EGEDKKDD 52
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 118-234 7.69e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 7.69e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564355627  118 RRLVTLITQLAKEITNkgvLKIQAENTNKAAKKFMEENERLKLVLKNND--NTE----EHVLETENKKLVEDKERLKTEL 191
Cdd:pfam05483 439 QELIFLLQAREKEIHD---LEIQLTAIKTSEEHYLKEVEDLKTELEKEKlkNIEltahCDKLLLENKELTQEASDMTLEL 515

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 564355627  192 KKAsdalfkaQNDVMTMKIQSERLSKEYDRLLKEHSELQNRLE 234
Cdd:pfam05483 516 KKH-------QEDIINCKKQEERMLKQIENLEEKEMNLRDELE 551
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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