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Conserved domains on  [gi|564342406|ref|XP_006234839|]
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leucine-rich repeat-containing protein 57 isoform X1 [Rattus norvegicus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
55-250 5.23e-32

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 121.58  E-value: 5.23e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  55 PSELQKLTsNLRTIDLSNNKIDSLPPlIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSSFGQLSA 134
Cdd:COG4886  106 NEELSNLT-NLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTN 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 135 LKTLSLSGNQLGALPPQLCSLRHLDVVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQISVrISCCPRLKVLRLEENcl 213
Cdd:COG4886  184 LKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLEtLDLSNNQLTDLPE-LGNLTNLEELDLSNN-- 260

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 564342406 214 ELSMLPQSiLSDSQICLLAVEGNLFEIKKLRELEGYD 250
Cdd:COG4886  261 QLTDLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLL 296
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
55-250 5.23e-32

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 121.58  E-value: 5.23e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  55 PSELQKLTsNLRTIDLSNNKIDSLPPlIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSSFGQLSA 134
Cdd:COG4886  106 NEELSNLT-NLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTN 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 135 LKTLSLSGNQLGALPPQLCSLRHLDVVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQISVrISCCPRLKVLRLEENcl 213
Cdd:COG4886  184 LKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLEtLDLSNNQLTDLPE-LGNLTNLEELDLSNN-- 260

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 564342406 214 ELSMLPQSiLSDSQICLLAVEGNLFEIKKLRELEGYD 250
Cdd:COG4886  261 QLTDLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLL 296
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
46-236 2.39e-16

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 78.59  E-value: 2.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  46 LKDRGLTEFPSELQKltsNLRTIDLSNNKIDSLPPLIIGKftlLKSLSLNNNKLTVLPDELCNlkKLETLSLNNNHLREL 125
Cdd:PRK15370 185 LKILGLTTIPACIPE---QITTLILDNNELKSLPENLQGN---IKTLYANSNQLTSIPATLPD--TIQEMELSINRITEL 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 126 PSSFGqlSALKTLSLSGNQLGALPPQLC-SLRHLDVVDlskNQIRSIPDTVGElQAIELNLNQNQISQISVRISccPRLK 204
Cdd:PRK15370 257 PERLP--SALQSLDLFHNKISCLPENLPeELRYLSVYD---NSIRTLPAHLPS-GITHLNVQSNSLTALPETLP--PGLK 328

                        170       180       190
                 ....*....|....*....|....*....|..
gi 564342406 205 VLRLEENCleLSMLPQSILSDSQIclLAVEGN 236
Cdd:PRK15370 329 TLEAGENA--LTSLPASLPPELQV--LDVSKN 356
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 46-213 5.75e-14

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 69.04  E-value: 5.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  46 LKDRGLTEFpsELQKLTSNLRTIDLSNNKIDSLPPLiiGKFTLLKSLSLNNNKLTVLpDELCNLKKLETLSLNNNHLREL 125
Cdd:cd21340    9 LNDKNITKI--DNLSLCKNLKVLYLYDNKITKIENL--EFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 126 pSSFGQLSALKTLSLSGNQLgALPPQLC-----------SLRHLDVvdlSKNQIRSIPDtVGELQAIE-LNLNQNQIS-- 191
Cdd:cd21340   84 -EGLENLTNLEELHIENQRL-PPGEKLTfdprslaalsnSLRVLNI---SGNNIDSLEP-LAPLRNLEqLDASNNQISdl 157

                        170       180
                 ....*....|....*....|...
gi 564342406 192 -QISVRISCCPRLKVLRLEENCL 213
Cdd:cd21340  158 eELLDLLSSWPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
63-122 7.91e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.99  E-value: 7.91e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564342406   63 SNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVL-PDELCNLKKLETLSLNNNHL 122
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
55-250 5.23e-32

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 121.58  E-value: 5.23e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  55 PSELQKLTsNLRTIDLSNNKIDSLPPlIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSSFGQLSA 134
Cdd:COG4886  106 NEELSNLT-NLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTN 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 135 LKTLSLSGNQLGALPPQLCSLRHLDVVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQISVrISCCPRLKVLRLEENcl 213
Cdd:COG4886  184 LKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLEtLDLSNNQLTDLPE-LGNLTNLEELDLSNN-- 260

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 564342406 214 ELSMLPQSiLSDSQICLLAVEGNLFEIKKLRELEGYD 250
Cdd:COG4886  261 QLTDLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLL 296
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
46-246 9.01e-29

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 112.72  E-value: 9.01e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  46 LKDRGLTEFPSELQKLTsNLRTIDLSNNKIDSLPPlIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLREL 125
Cdd:COG4886  143 LSNNQLTDLPEPLGNLT-NLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDL 220

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 126 PSSFGQLSALKTLSLSGNQLGALPpQLCSLRHLDVVDLSKNQIRSIPDTVGELQAIELNLNQNQISQISVRISCCPRLKV 205
Cdd:COG4886  221 PEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLN 299

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 564342406 206 LRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKKLREL 246
Cdd:COG4886  300 SLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTL 340
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
46-236 2.39e-16

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 78.59  E-value: 2.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  46 LKDRGLTEFPSELQKltsNLRTIDLSNNKIDSLPPLIIGKftlLKSLSLNNNKLTVLPDELCNlkKLETLSLNNNHLREL 125
Cdd:PRK15370 185 LKILGLTTIPACIPE---QITTLILDNNELKSLPENLQGN---IKTLYANSNQLTSIPATLPD--TIQEMELSINRITEL 256

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 126 PSSFGqlSALKTLSLSGNQLGALPPQLC-SLRHLDVVDlskNQIRSIPDTVGElQAIELNLNQNQISQISVRISccPRLK 204
Cdd:PRK15370 257 PERLP--SALQSLDLFHNKISCLPENLPeELRYLSVYD---NSIRTLPAHLPS-GITHLNVQSNSLTALPETLP--PGLK 328

                        170       180       190
                 ....*....|....*....|....*....|..
gi 564342406 205 VLRLEENCleLSMLPQSILSDSQIclLAVEGN 236
Cdd:PRK15370 329 TLEAGENA--LTSLPASLPPELQV--LDVSKN 356
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 63-213 2.25e-15

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 75.65  E-value: 2.25e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  63 SNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR-ELPSSFGQLSALKTLSL 140
Cdd:PLN00113 140 PNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMKSLKWIYL 219

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 564342406 141 SGNQL-GALPPQ---LCSLRHLDVVdlSKNQIRSIPDTVGELQAIE-LNLNQNQIS-QISVRISCCPRLKVLRLEENCL 213
Cdd:PLN00113 220 GYNNLsGEIPYEiggLTSLNHLDLV--YNNLTGPIPSSLGNLKNLQyLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSL 296
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 62-181 1.74e-14

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 72.96  E-value: 1.74e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  62 TSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR-ELPSSFGQLSALKTLS 139
Cdd:PLN00113 474 SKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLD 553

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 564342406 140 LSGNQL-GALPPQLCSLRHLDVVDLSKNQIR-SIPDTvGELQAI 181
Cdd:PLN00113 554 LSQNQLsGEIPKNLGNVESLVQVNISHNHLHgSLPST-GAFLAI 596
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 46-213 5.75e-14

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 69.04  E-value: 5.75e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  46 LKDRGLTEFpsELQKLTSNLRTIDLSNNKIDSLPPLiiGKFTLLKSLSLNNNKLTVLpDELCNLKKLETLSLNNNHLREL 125
Cdd:cd21340    9 LNDKNITKI--DNLSLCKNLKVLYLYDNKITKIENL--EFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 126 pSSFGQLSALKTLSLSGNQLgALPPQLC-----------SLRHLDVvdlSKNQIRSIPDtVGELQAIE-LNLNQNQIS-- 191
Cdd:cd21340   84 -EGLENLTNLEELHIENQRL-PPGEKLTfdprslaalsnSLRVLNI---SGNNIDSLEP-LAPLRNLEqLDASNNQISdl 157

                        170       180
                 ....*....|....*....|...
gi 564342406 192 -QISVRISCCPRLKVLRLEENCL 213
Cdd:cd21340  158 eELLDLLSSWPSLRELDLTGNPV 180
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
11-222 9.80e-13

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 67.80  E-value: 9.80e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  11 EALGARLRELSrgARMGNsaLRAHVETAQKT-GVFQLKDRGLTEFPselQKLTSNLRTIDLSNNKIDSLPPLIIGKftlL 89
Cdd:PRK15370 216 ENLQGNIKTLY--ANSNQ--LTSIPATLPDTiQEMELSINRITELP---ERLPSALQSLDLFHNKISCLPENLPEE---L 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  90 KSLSLNNNKLTVLPDELCNlkKLETLSLNNNHLRELPSSFGQlsALKTLSLSGNQLGALPPQLCSlrHLDVVDLSKNQIR 169
Cdd:PRK15370 286 RYLSVYDNSIRTLPAHLPS--GITHLNVQSNSLTALPETLPP--GLKTLEAGENALTSLPASLPP--ELQVLDVSKNQIT 359

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 564342406 170 SIPDTV-GELQaiELNLNQNQISQISVRISCCprLKVLRLEENclELSMLPQSI 222
Cdd:PRK15370 360 VLPETLpPTIT--TLDVSRNALTNLPENLPAA--LQIMQASRN--NLVRLPESL 407
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
51-191 1.04e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 61.49  E-value: 1.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  51 LTEFPSELQKLTsNLRTIDLSNNKIDSLPPLiiGKFTLLKSLSLNNNKLTVLPdELCNLKKLETLSLNNNHLRELPSSFG 130
Cdd:COG4886  217 LTDLPEPLANLT-NLETLDLSNNQLTDLPEL--GNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQLTDLKLKEL 292

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564342406 131 QLSALKTLSLSGNQLGALPPQLCSLRHLDVVDLSKNQIRSIPDTVGELQAIELNLNQNQIS 191
Cdd:COG4886  293 ELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLL 353
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
58-222 3.32e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 59.95  E-value: 3.32e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  58 LQKLTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNNHLRELPSSFGQLSALKT 137
Cdd:COG4886   21 LTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTE 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 138 LS-----------------LSGNQLGALPPQLCSLRHLDVVDLSKNQIRSIPDTVGELQAIE-LNLNQNQISQISVRISC 199
Cdd:COG4886  101 LDlsgneelsnltnlesldLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKsLDLSNNQLTDLPEELGN 180

                        170       180
                 ....*....|....*....|...
gi 564342406 200 CPRLKVLRLEENclELSMLPQSI 222
Cdd:COG4886  181 LTNLKELDLSNN--QITDLPEPL 201
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
31-246 1.13e-09

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 58.63  E-value: 1.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  31 LRAHVETaqktgvFQLKDRGLTEFPSelqkLTSNLRTIDLSNNKIDSLPPLIIGkftlLKSLSLNNNKLT---VLPDELC 107
Cdd:PRK15387 220 LPAHITT------LVIPDNNLTSLPA----LPPELRTLEVSGNQLTSLPVLPPG----LLELSIFSNPLThlpALPSGLC 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 108 NL--------------KKLETLSLNNNHLRELPSSFGQL-----------------SALKTLSLSGNQLGALPP------ 150
Cdd:PRK15387 286 KLwifgnqltslpvlpPGLQELSVSDNQLASLPALPSELcklwaynnqltslptlpSGLQELSVSDNQLASLPTlpsely 365

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 151 -------QLCSL----RHLDVVDLSKNQIRSIPDTVGELQaiELNLNQNQISQISVRISCCPRLKVLRleencLELSMLP 219
Cdd:PRK15387 366 klwaynnRLTSLpalpSGLKELIVSGNRLTSLPVLPSELK--ELMVSGNRLTSLPMLPSGLLSLSVYR-----NQLTRLP 438

                        250       260
                 ....*....|....*....|....*..
gi 564342406 220 QSILSDSQICLLAVEGNLFEIKKLREL 246
Cdd:PRK15387 439 ESLIHLSSETTVNLEGNPLSERTLQAL 465
LRR_8 pfam13855
Leucine rich repeat;
63-122 7.91e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.99  E-value: 7.91e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564342406   63 SNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLTVL-PDELCNLKKLETLSLNNNHL 122
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
29-156 1.48e-08

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 55.09  E-value: 1.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  29 SALRAHVetaqKTGVFQL--KDRGLTEFPselQKLTSNLRTIDLSNNKIDSLPPLIIGKftlLKSLSLNNNKLTVLPDEL 106
Cdd:PRK15370 296 RTLPAHL----PSGITHLnvQSNSLTALP---ETLPPGLKTLEAGENALTSLPASLPPE---LQVLDVSKNQITVLPETL 365

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 564342406 107 CnlKKLETLSLNNNHLRELPSSFGqlSALKTLSLSGNQLGALPPQLCSLR 156
Cdd:PRK15370 366 P--PTITTLDVSRNALTNLPENLP--AALQIMQASRNNLVRLPESLPHFR 411
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 58-191 3.22e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 54.08  E-value: 3.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  58 LQKLTSnlrtIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR-ELPSSFGQLSAL 135
Cdd:PLN00113 283 LQKLIS----LDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTgKIPVALTSLPRLQVLQLWSNKFSgEIPKNLGKHNNL 358

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 564342406 136 KTLSLSGNQL-GALPPQLCSLRHLDVVDLSKNQIRS-IPDTVGELQAIE-LNLNQNQIS 191
Cdd:PLN00113 359 TVLDLSTNNLtGEIPEGLCSSGNLFKLILFSNSLEGeIPKSLGACRSLRrVRLQDNSFS 417
LRR_8 pfam13855
Leucine rich repeat;
89-145 3.69e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.06  E-value: 3.69e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 564342406   89 LKSLSLNNNKLTVLPDE-LCNLKKLETLSLNNNHLREL-PSSFGQLSALKTLSLSGNQL 145
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 43-213 8.84e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 52.93  E-value: 8.84e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  43 VFQLKDRGLT-EFPSELQKlTSNLRTIDLSNNKIDS-LPPLIIGKFTLLKSLSLNNNKLTVLPDELCNLKKLETLSLNNN 120
Cdd:PLN00113 336 VLQLWSNKFSgEIPKNLGK-HNNLTVLDLSTNNLTGeIPEGLCSSGNLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDN 414

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 121 HLR-ELPSSFGQL------------------------SALKTLSLSGNQLGALPPQLCSLRHLDVVDLSKNQIR-SIPDT 174
Cdd:PLN00113 415 SFSgELPSEFTKLplvyfldisnnnlqgrinsrkwdmPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSgAVPRK 494

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 564342406 175 VGELQAI-ELNLNQNQIS-QISVRISCCPRLKVLRLEENCL 213
Cdd:PLN00113 495 LGSLSELmQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQL 535
PLN03150 PLN03150
hypothetical protein; Provisional
 46-130 9.90e-08

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.51  E-value: 9.90e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  46 LKDRGLTEF-PSELQKLtSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR 123
Cdd:PLN03150 425 LDNQGLRGFiPNDISKL-RHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLS 503


                 ....*...
gi 564342406 124 -ELPSSFG 130
Cdd:PLN03150 504 gRVPAALG 511
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 48-216 2.03e-07

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 51.20  E-value: 2.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  48 DRGLTEFPSELQKlTSNLRTIDLSNNKI--DSLPPLI-IGKFTLLKSLSLNNNKL---------TVLPDELCNLKK--LE 113
Cdd:cd00116   67 PRGLQSLLQGLTK-GCGLQELDLSDNALgpDGCGVLEsLLRSSSLQELKLNNNGLgdrglrllaKGLKDLPPALEKlvLG 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 114 TLSLNNNHLRELPSSFGQLSALKTLSLSGNQLG-----ALPPQLCSLRHLDVVDLSKNQIRS-----IPDTVGELQAIE- 182
Cdd:cd00116  146 RNRLEGASCEALAKALRANRDLKELNLANNGIGdagirALAEGLKANCNLEVLDLNNNGLTDegasaLAETLASLKSLEv 225

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 564342406 183 LNLNQNQISQISVR------ISCCPRLKVLRLEENCLELS 216
Cdd:cd00116  226 LNLGDNNLTDAGAAalasalLSPNISLLTLSLSCNDITDD 265
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 48-191 6.15e-07

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 49.79  E-value: 6.15e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  48 DRGLTEFPSELQKLTSnLRTIDLSNNKIDSLPPLIIGKF----TLLKSLSLNNNKLTV-----LPDELCNLKKLETLSLN 118
Cdd:COG5238  222 DEGAEILAEALKGNKS-LTTLDLSNNQIGDEGVIALAEAlknnTTVETLYLSGNQIGAegaiaLAKALQGNTTLTSLDLS 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 119 NNHLRE-----LPSSFGQLSALKTLSLSGNQLG-----ALPPQLCSLRHLDVVDLSKNQIRS------IPDTVGELQAIE 182
Cdd:COG5238  301 VNRIGDegaiaLAEGLQGNKTLHTLNLAYNGIGaqgaiALAKALQENTTLHSLDLSDNQIGDegaialAKYLEGNTTLRE 380


                 ....*....
gi 564342406 183 LNLNQNQIS 191
Cdd:COG5238  381 LNLGKNNIG 389
PLN03150 PLN03150
hypothetical protein; Provisional
 68-152 9.78e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 49.43  E-value: 9.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  68 IDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR-ELPSSFGQLSALKTLSLSGNQL 145
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSL 502


                 ....*...
gi 564342406 146 -GALPPQL 152
Cdd:PLN03150 503 sGRVPAAL 510
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 62-213 1.43e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 49.08  E-value: 1.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  62 TSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNL-KKLETLSLNNNHLRElPSSFGQLSALKTLS 139
Cdd:PLN00113  68 SSRVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSgPIPDDIFTTsSSLRYLNLSNNNFTG-SIPRGSIPNLETLD 146

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564342406 140 LSGNQL-GALPPQLCSLRHLDVVDLSKNQIRS-IPDTVGELQAIE-LNLNQNQ-ISQISVRISCCPRLKVLRLEENCL 213
Cdd:PLN00113 147 LSNNMLsGEIPNDIGSFSSLKVLDLGGNVLVGkIPNSLTNLTSLEfLTLASNQlVGQIPRELGQMKSLKWIYLGYNNL 224
LRR_8 pfam13855
Leucine rich repeat;
111-168 4.11e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.28  E-value: 4.11e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  111 KLETLSLNNNHLREL-PSSFGQLSALKTLSLSGNQLGALPPQ-LCSLRHLDVVDLSKNQI 168
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 45-195 8.34e-06

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 46.32  E-value: 8.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  45 QLKDRGLTEFPSELQKLTsNLRTIDLSNNKIDSLPPLIIGK----FTLLKSLSLNNNKLT-----VLPDELCNLKKLETL 115
Cdd:COG5238  191 QIGDEGIEELAEALTQNT-TVTTLWLKRNPIGDEGAEILAEalkgNKSLTTLDLSNNQIGdegviALAEALKNNTTVETL 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 116 SLNNNHLRE-----LPSSFGQLSALKTLSLSGNQLG-----ALPPQLCSLRHLDVVDLSKNQI-----RSIPDTVGELQA 180
Cdd:COG5238  270 YLSGNQIGAegaiaLAKALQGNTTLTSLDLSVNRIGdegaiALAEGLQGNKTLHTLNLAYNGIgaqgaIALAKALQENTT 349

                        170
                 ....*....|....*.
gi 564342406 181 IE-LNLNQNQISQISV 195
Cdd:COG5238  350 LHsLDLSDNQIGDEGA 365
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 62-213 3.39e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.19  E-value: 3.39e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  62 TSNLRTIDLSNNKIDSLPPLIIGKFTL-----LKSLSLNNNKLTV-----LPDELCNLKKLETLSLNNNHLRE-----LP 126
Cdd:cd00116  107 SSSLQELKLNNNGLGDRGLRLLAKGLKdlppaLEKLVLGRNRLEGasceaLAKALRANRDLKELNLANNGIGDagiraLA 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 127 SSFGQLSALKTLSLSGN--------QLGALPPQLCSLRHLdvvDLSKNQIRSIPdtvgeLQAIELNLNQNQISQISVRIS 198
Cdd:cd00116  187 EGLKANCNLEVLDLNNNgltdegasALAETLASLKSLEVL---NLGDNNLTDAG-----AAALASALLSPNISLLTLSLS 258

                        170       180       190
                 ....*....|....*....|....*....|..
gi 564342406 199 CC-----------------PRLKVLRLEENCL 213
Cdd:cd00116  259 CNditddgakdlaevlaekESLLELDLRGNKF 290
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 109-247 4.42e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.54  E-value: 4.42e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406 109 LKKLETLSLNNNHLRELPsSFGQLSALKTLSLSGNQLGALpPQLCSLRHLDVVDLSKNQIRSIPDTVGELQAIELNLNQN 188
Cdd:cd21340    1 LKRITHLYLNDKNITKID-NLSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGN 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564342406 189 QISQISvRISCCPRLKVLRLEENCLELSML----PQSILSDSQ-ICLLAVEGN----LFEIKKLRELE 247
Cdd:cd21340   79 RISVVE-GLENLTNLEELHIENQRLPPGEKltfdPRSLAALSNsLRVLNISGNnidsLEPLAPLRNLE 145
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 53-145 7.99e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.60  E-value: 7.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  53 EFPSELQKlTSNLRTIDLSNNKIDSLPPLIIGKFTLLKSLSLNNNKLT-VLPDELCNLKKLETLSLNNNHLR-ELPSSfG 130
Cdd:PLN00113 514 EIPDELSS-CKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHLHgSLPST-G 591

                         90
                 ....*....|....*
gi 564342406 131 QLSALKTLSLSGNQL 145
Cdd:PLN00113 592 AFLAINASAVAGNID 606
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
56-162 9.03e-04

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 40.53  E-value: 9.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406  56 SELQKLTSNLRTIDLSNNKIDSLPPLIIGkftlLKSLSLNNNKLTVLPDELCNLKKLETLSLNNN--------HLRELPS 127
Cdd:PRK15387 395 TSLPVLPSELKELMVSGNRLTSLPMLPSG----LLSLSVYRNQLTRLPESLIHLSSETTVNLEGNplsertlqALREITS 470

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 564342406 128 SFGQLSALKTLSLSgnqlGALPPQLCSLRHLDVVD 162
Cdd:PRK15387 471 APGYSGPIIRFDMA----GASAPRETRALHLAAAD 501
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 14-193 3.60e-03

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 38.70  E-value: 3.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406   14 GARLRELSRGARMGNSALRAHVETAQKTGVFQLKDRGLTEFPSELQklTSNLRTIDLSNNKIDSLppliIGKFTLLKSLs 93
Cdd:PLN03210  700 GINLKSLYRLNLSGCSRLKSFPDISTNISWLDLDETAIEEFPSNLR--LENLDELILCEMKSEKL----WERVQPLTPL- 772

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564342406   94 lnnnkLTVLPDELCNLkkleTLSlNNNHLRELPSSFGQLSALKTLSLSG-NQLGALPPQLcSLRHLDVVDLSK-NQIRSI 171
Cdd:PLN03210  773 -----MTMLSPSLTRL----FLS-DIPSLVELPSSIQNLHKLEHLEIENcINLETLPTGI-NLESLESLDLSGcSRLRTF 841

                         170       180
                  ....*....|....*....|..
gi 564342406  172 PDTVGELQaiELNLNQNQISQI 193
Cdd:PLN03210  842 PDISTNIS--DLNLSRTGIEEV 861
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 89-122 4.89e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 34.14  E-value: 4.89e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 564342406   89 LKSLSLNNNKLTVLPdELCNLKKLETLSLNNNHL 122
Cdd:pfam12799   3 LEVLDLSNNQITDIP-PLAKLPNLETLDLSGNNK 35
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 64-99 7.26e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 33.76  E-value: 7.26e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 564342406   64 NLRTIDLSNNKIDSLPPLiiGKFTLLKSLSLNNNKL 99
Cdd:pfam12799   2 NLEVLDLSNNQITDIPPL--AKLPNLETLDLSGNNK 35
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 110-145 9.67e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 33.37  E-value: 9.67e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 564342406  110 KKLETLSLNNNHLRELPsSFGQLSALKTLSLSGNQL 145
Cdd:pfam12799   1 PNLEVLDLSNNQITDIP-PLAKLPNLETLDLSGNNK 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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