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Conserved domains on  [gi|564333158|ref|XP_006231224|]
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alpha/beta hydrolase domain-containing protein 17B isoform X1 [Rattus norvegicus]

Protein Classification

alpha/beta hydrolase( domain architecture ID 11437497)

alpha/beta hydrolase catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

CATH:  3.40.50.1820
EC:  3.-.-.-
Gene Ontology:  GO:0016787

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
58-285 4.31e-43

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


:

Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 147.75  E-value: 4.31e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  58 YSSREKDAIECFMTRTSKGNRIACM-FVRCSPNAKY-TLLFSHGNAVDLGQMSSF---YIGLGSrincNIFSYDYSGYGA 132
Cdd:COG1073    2 FPPSDKVNKEDVTFKSRDGIKLAGDlYLPAGASKKYpAVVVAHGNGGVKEQRALYaqrLAELGF----NVLAFDYRGYGE 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 133 SSGKPTEKNLYA--DVEAAWLALRTRYGIRPENVIIYGQSIGTVPSVDLAARYES-AAVILHSPLTSGMRVA-------- 201
Cdd:COG1073   78 SEGEPREEGSPErrDARAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPRvKAVILDSPFTSLEDLAaqrakear 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 202 ---FPDTKKTYCF-------DAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHND--VEL 269
Cdd:COG1073  158 gayLPGVPYLPNVrlasllnDEFDPLAKIEKISRPLLFIHGEKDEAVPFYMSEDLYEAAAEPKELLIVPGAGHVDlyDRP 237
                        250
                 ....*....|....*.
gi 564333158 270 YGQYLERLKQFVSQEL 285
Cdd:COG1073  238 EEEYFDKLAEFFKKNL 253
 
Name Accession Description Interval E-value
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
58-285 4.31e-43

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 147.75  E-value: 4.31e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  58 YSSREKDAIECFMTRTSKGNRIACM-FVRCSPNAKY-TLLFSHGNAVDLGQMSSF---YIGLGSrincNIFSYDYSGYGA 132
Cdd:COG1073    2 FPPSDKVNKEDVTFKSRDGIKLAGDlYLPAGASKKYpAVVVAHGNGGVKEQRALYaqrLAELGF----NVLAFDYRGYGE 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 133 SSGKPTEKNLYA--DVEAAWLALRTRYGIRPENVIIYGQSIGTVPSVDLAARYES-AAVILHSPLTSGMRVA-------- 201
Cdd:COG1073   78 SEGEPREEGSPErrDARAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPRvKAVILDSPFTSLEDLAaqrakear 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 202 ---FPDTKKTYCF-------DAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHND--VEL 269
Cdd:COG1073  158 gayLPGVPYLPNVrlasllnDEFDPLAKIEKISRPLLFIHGEKDEAVPFYMSEDLYEAAAEPKELLIVPGAGHVDlyDRP 237
                        250
                 ....*....|....*.
gi 564333158 270 YGQYLERLKQFVSQEL 285
Cdd:COG1073  238 EEEYFDKLAEFFKKNL 253
PHA02857 PHA02857
monoglyceride lipase; Provisional
66-265 1.04e-09

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 57.97  E-value: 1.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  66 IECFMTrtSKGNRIACMFVRCSPNAKYTLLFSHGNavdlGQMSSFYIGLG---SRINCNIFSYDYSGYGASSGKP---TE 139
Cdd:PHA02857   2 ANCMFN--LDNDYIYCKYWKPITYPKALVFISHGA----GEHSGRYEELAeniSSLGILVFSHDHIGHGRSNGEKmmiDD 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 140 KNLYA-DVEAAWLALRTRYGIRPenVIIYGQSIGTVPSVDLAARYES--AAVILHSPLTSGMRVAFPDTKKTYCFDAFP- 215
Cdd:PHA02857  76 FGVYVrDVVQHVVTIKSTYPGVP--VFLLGHSMGATISILAAYKNPNlfTAMILMSPLVNAEAVPRLNLLAAKLMGIFYp 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 216 --------------NID---------------------------------KISKITSPVLIIHGTEDEVIDFSHGLALFE 248
Cdd:PHA02857 154 nkivgklcpesvsrDMDevykyqydplvnhekikagfasqvlkatnkvrkIIPKIKTPILILQGTNNEISDVSGAYYFMQ 233
                        250
                 ....*....|....*..
gi 564333158 249 RCQRPVEPLWVEGAGHN 265
Cdd:PHA02857 234 HANCNREIKIYEGAKHH 250
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
88-264 2.51e-08

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 53.37  E-value: 2.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158   88 PNAKYTLLFSHGnavdLGQMSSFYIGLGSRIN-CNI--FSYDYSGYGASSGK----PTEKNLYADVEAAWLALRTRYGIR 160
Cdd:pfam12146   1 GEPRAVVVLVHG----LGEHSGRYAHLADALAaQGFavYAYDHRGHGRSDGKrghvPSFDDYVDDLDTFVDKIREEHPGL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  161 PenVIIYGQSIGTVPSVDLAARYES--AAVILHSP--------LTSGMRVA-------FPD------TKKTYC------- 210
Cdd:pfam12146  77 P--LFLLGHSMGGLIAALYALRYPDkvDGLILSAPalkikpylAPPILKLLakllgklFPRlrvpnnLLPDSLsrdpevv 154
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564333158  211 --FDAFPNI-DKIS-------------------KITSPVLIIHGTEDEVIDFSHGLALFERCQRP-VEPLWVEGAGH 264
Cdd:pfam12146 155 aaYAADPLVhGGISartlyelldagerllrraaAITVPLLLLHGGADRVVDPAGSREFYERAGSTdKTLKLYPGLYH 231
 
Name Accession Description Interval E-value
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
58-285 4.31e-43

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 147.75  E-value: 4.31e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  58 YSSREKDAIECFMTRTSKGNRIACM-FVRCSPNAKY-TLLFSHGNAVDLGQMSSF---YIGLGSrincNIFSYDYSGYGA 132
Cdd:COG1073    2 FPPSDKVNKEDVTFKSRDGIKLAGDlYLPAGASKKYpAVVVAHGNGGVKEQRALYaqrLAELGF----NVLAFDYRGYGE 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 133 SSGKPTEKNLYA--DVEAAWLALRTRYGIRPENVIIYGQSIGTVPSVDLAARYES-AAVILHSPLTSGMRVA-------- 201
Cdd:COG1073   78 SEGEPREEGSPErrDARAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPRvKAVILDSPFTSLEDLAaqrakear 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 202 ---FPDTKKTYCF-------DAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHND--VEL 269
Cdd:COG1073  158 gayLPGVPYLPNVrlasllnDEFDPLAKIEKISRPLLFIHGEKDEAVPFYMSEDLYEAAAEPKELLIVPGAGHVDlyDRP 237
                        250
                 ....*....|....*.
gi 564333158 270 YGQYLERLKQFVSQEL 285
Cdd:COG1073  238 EEEYFDKLAEFFKKNL 253
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
72-285 3.36e-27

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 105.48  E-value: 3.36e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  72 RTSKGNRIACMFVRCSPNAKY-TLLFSHGNAvdlGQMSSFYIGLGSRIN---CNIFSYDYSGYGASSGKPTEKNlYADVE 147
Cdd:COG1506    3 KSADGTTLPGWLYLPADGKKYpVVVYVHGGP---GSRDDSFLPLAQALAsrgYAVLAPDYRGYGESAGDWGGDE-VDDVL 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 148 AAWLALRTRYGIRPENVIIYGQSIGTVPSVDLAARYES--AAVILHSPLTS-----------GMRVAFPDTKKTYCFDAF 214
Cdd:COG1506   79 AAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDrfKAAVALAGVSDlrsyygttreyTERLMGGPWEDPEAYAAR 158
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564333158 215 PNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQR---PVEPLWVEGAGHNDV-ELYGQYLERLKQFVSQEL 285
Cdd:COG1506  159 SPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKagkPVELLVYPGEGHGFSgAGAPDYLERILDFLDRHL 233
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
72-283 1.94e-23

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 95.07  E-value: 1.94e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  72 RTSKGNRIACMFVRCSPNAKYTLLFSHGNAVDLGQMSSFYIGLGSRiNCNIFSYDYSGYGASSGK----PTEKNLYADVE 147
Cdd:COG2267    9 PTRDGLRLRGRRWRPAGSPRGTVVLVHGLGEHSGRYAELAEALAAA-GYAVLAFDLRGHGRSDGPrghvDSFDDYVDDLR 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 148 AAWLALRTRYGIRpenVIIYGQSIGTVPSVDLAARYES--AAVILHSPLtsgmRVAFPDTKKTYCF-DAFPNIDKISKIT 224
Cdd:COG2267   88 AALDALRARPGLP---VVLLGHSMGGLIALLYAARYPDrvAGLVLLAPA----YRADPLLGPSARWlRALRLAEALARID 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564333158 225 SPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHNDV--ELYGQYLERLKQFVSQ 283
Cdd:COG2267  161 VPVLVLHGGADRVVPPEAARRLAARLSPDVELVLLPGARHELLnePAREEVLAAILAWLER 221
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
82-283 3.15e-18

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 81.20  E-value: 3.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  82 MFVRCSPNAKYTLLFSHGNAVDLGQMSSFYIGLGSRinCNIFSYDYSGYGASSgKPTEKNLYADVEAAWLALRTRYGIRP 161
Cdd:COG0596   14 LHYREAGPDGPPVVLLHGLPGSSYEWRPLIPALAAG--YRVIAPDLRGHGRSD-KPAGGYTLDDLADDLAALLDALGLER 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 162 enVIIYGQSIGTVPSVDLAARYES--AAVILHSPLTSGMRVAFPDTKKTY-----CFDAFPNID---KISKITSPVLIIH 231
Cdd:COG0596   91 --VVLVGHSMGGMVALELAARHPErvAGLVLVDEVLAALAEPLRRPGLAPealaaLLRALARTDlreRLARITVPTLVIW 168
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 564333158 232 GTEDEVIDFSHGLALFERCQRpVEPLWVEGAGHN-DVELYGQYLERLKQFVSQ 283
Cdd:COG0596  169 GEKDPIVPPALARRLAELLPN-AELVVLPGAGHFpPLEQPEAFAAALRDFLAR 220
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
88-283 1.23e-14

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 71.90  E-value: 1.23e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  88 PNAKYTLLFSHGNAVDLGQMSSfyigLGSRIN---CNIFSYDYSGYGASSG---KPTEKNLYADVEAAWLALRTRYgirp 161
Cdd:COG1647   12 EGGRKGVLLLHGFTGSPAEMRP----LAEALAkagYTVYAPRLPGHGTSPEdllKTTWEDWLEDVEEAYEILKAGY---- 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 162 ENVIIYGQSIGTVPSVDLAARYES-AAVILHSP-----------------LTSGMRVAFPDTKKT----YCFDAFPNI-- 217
Cdd:COG1647   84 DKVIVIGLSMGGLLALLLAARYPDvAGLVLLSPalkiddpsapllpllkyLARSLRGIGSDIEDPevaeYAYDRTPLRal 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 218 -----------DKISKITSPVLIIHGTEDEVIDFSHGLALFERC-QRPVEPLWVEGAGH---NDVELyGQYLERLKQFVS 282
Cdd:COG1647  164 aelqrlirevrRDLPKITAPTLIIQSRKDEVVPPESARYIYERLgSPDKELVWLEDSGHvitLDKDR-EEVAEEILDFLE 242

                 .
gi 564333158 283 Q 283
Cdd:COG1647  243 R 243
YpfH COG0400
Predicted esterase [General function prediction only];
88-285 3.36e-10

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 58.38  E-value: 3.36e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  88 PNAKYTLLFSHGNAVDLGQMSSFYiglgsRINCNIFSYDYSGYGASSgkpteknlyADVEAAWLALRTRYGIRPENVIIY 167
Cdd:COG0400   29 ALPGAAVLAPRAPVPEGPGGRAWF-----DLSFLEGREDEEGLAAAA---------EALAAFIDELEARYGIDPERIVLA 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 168 GQSIGTVPSVDLAARYES--AAVILHSPltsgmRVAFPDTKKTYCFDAfpnidkiSKItsPVLIIHGTEDEVIDFSHGLA 245
Cdd:COG0400   95 GFSQGAAMALSLALRRPEllAGVVALSG-----YLPGEEALPAPEAAL-------AGT--PVFLAHGTQDPVIPVERARE 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 564333158 246 LFERCQR---PVEPLWVEGaGHndvELYGQYLERLKQFVSQEL 285
Cdd:COG0400  161 AAEALEAagaDVTYREYPG-GH---EISPEELADARAWLAERL 199
COG2945 COG2945
Alpha/beta superfamily hydrolase [General function prediction only];
129-285 1.03e-09

Alpha/beta superfamily hydrolase [General function prediction only];


Pssm-ID: 442188 [Multi-domain]  Cd Length: 201  Bit Score: 57.09  E-value: 1.03e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 129 GYGASSGK----PTEKnlyADVEAA--WLalRTRYgirPENVIIYGQSIGTvpsvDLAARY-----ESAAVILHSPLTSg 197
Cdd:COG2945   65 GVGRSEGEfdegRGEL---DDAAAAldWL--RAQN---PLPLWLAGFSFGA----YVALQLamrlpEVEGLILVAPPVN- 131
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 198 mRVAFPDtkktycfdafpnidkISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHndveLYGQYLERL 277
Cdd:COG2945  132 -RYDFSF---------------LAPCPAPTLVIHGEQDEVVPPAEVLDWARPLSPPLPVVVVPGADH----FFHGKLDEL 191

                 ....*...
gi 564333158 278 KQFVSQEL 285
Cdd:COG2945  192 KELVARYL 199
PHA02857 PHA02857
monoglyceride lipase; Provisional
66-265 1.04e-09

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 57.97  E-value: 1.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  66 IECFMTrtSKGNRIACMFVRCSPNAKYTLLFSHGNavdlGQMSSFYIGLG---SRINCNIFSYDYSGYGASSGKP---TE 139
Cdd:PHA02857   2 ANCMFN--LDNDYIYCKYWKPITYPKALVFISHGA----GEHSGRYEELAeniSSLGILVFSHDHIGHGRSNGEKmmiDD 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 140 KNLYA-DVEAAWLALRTRYGIRPenVIIYGQSIGTVPSVDLAARYES--AAVILHSPLTSGMRVAFPDTKKTYCFDAFP- 215
Cdd:PHA02857  76 FGVYVrDVVQHVVTIKSTYPGVP--VFLLGHSMGATISILAAYKNPNlfTAMILMSPLVNAEAVPRLNLLAAKLMGIFYp 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 216 --------------NID---------------------------------KISKITSPVLIIHGTEDEVIDFSHGLALFE 248
Cdd:PHA02857 154 nkivgklcpesvsrDMDevykyqydplvnhekikagfasqvlkatnkvrkIIPKIKTPILILQGTNNEISDVSGAYYFMQ 233
                        250
                 ....*....|....*..
gi 564333158 249 RCQRPVEPLWVEGAGHN 265
Cdd:PHA02857 234 HANCNREIKIYEGAKHH 250
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
88-264 2.51e-08

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 53.37  E-value: 2.51e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158   88 PNAKYTLLFSHGnavdLGQMSSFYIGLGSRIN-CNI--FSYDYSGYGASSGK----PTEKNLYADVEAAWLALRTRYGIR 160
Cdd:pfam12146   1 GEPRAVVVLVHG----LGEHSGRYAHLADALAaQGFavYAYDHRGHGRSDGKrghvPSFDDYVDDLDTFVDKIREEHPGL 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  161 PenVIIYGQSIGTVPSVDLAARYES--AAVILHSP--------LTSGMRVA-------FPD------TKKTYC------- 210
Cdd:pfam12146  77 P--LFLLGHSMGGLIAALYALRYPDkvDGLILSAPalkikpylAPPILKLLakllgklFPRlrvpnnLLPDSLsrdpevv 154
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 564333158  211 --FDAFPNI-DKIS-------------------KITSPVLIIHGTEDEVIDFSHGLALFERCQRP-VEPLWVEGAGH 264
Cdd:pfam12146 155 aaYAADPLVhGGISartlyelldagerllrraaAITVPLLLLHGGADRVVDPAGSREFYERAGSTdKTLKLYPGLYH 231
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
140-264 1.06e-07

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 51.46  E-value: 1.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  140 KNLYADVEAAWLALRTRYGIRPENVIIYGQS--------------------IGTVPSVDLAaRYESAAvilHSPLTSG-M 198
Cdd:pfam00326  42 QNEFDDFIAAAEYLIEQGYTDPDRLAIWGGSyggyltgaalnqrpdlfkaaVAHVPVVDWL-AYMSDT---SLPFTERyM 117
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 564333158  199 RVAFPDTKKTYcFDAFPNID--KISKITSPVLIIHGTEDEVIDFSHGLALFERCQR---PVEPLWVEGAGH 264
Cdd:pfam00326 118 EWGNPWDNEEG-YDYLSPYSpaDNVKVYPPLLLIHGLLDDRVPPWQSLKLVAALQRkgvPFLLLIFPDEGH 187
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
145-264 4.02e-07

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 49.49  E-value: 4.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 145 DVEAAWLALRTR---YGIRPENVIIYGQSIG--TVPSVDLAARYES----AAVILHSPLTSgMRVAfPDTkktYCFDAFP 215
Cdd:COG0657   66 DAYAALRWLRANaaeLGIDPDRIAVAGDSAGghLAAALALRARDRGgprpAAQVLIYPVLD-LTAS-PLR---ADLAGLP 140
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 564333158 216 nidkiskitsPVLIIHGTEDEVIDfsHGLALFERCQR---PVEPLWVEGAGH 264
Cdd:COG0657  141 ----------PTLIVTGEADPLVD--ESEALAAALRAagvPVELHVYPGGGH 180
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
144-264 1.00e-06

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 48.42  E-value: 1.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158 144 ADVEAAWLALRTRYGIRPENVIIYGQSIGTVPSVDLAARYE--SAAVILHSPLtsgmrvafpdtkktycfDAFPNIDKIS 221
Cdd:COG0412   91 ADLRAALDWLKAQPEVDAGRVGVVGFCFGGGLALLAAARGPdlAAAVSFYGGL-----------------PADDLLDLAA 153
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 564333158 222 KITSPVLIIHGTEDEVIDFSHGLALFERCQR---PVEPLWVEGAGH 264
Cdd:COG0412  154 RIKAPVLLLYGEKDPLVPPEQVAALEAALAAagvDVELHVYPGAGH 199
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
92-198 2.88e-05

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 44.42  E-value: 2.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158   92 YTLLFSHGnavdLGQMSSFYIGLG---SRINCNIFSYDYSGYGASSGKPTEKNLYADVEAAWL-ALRTRYGIrpENVIIY 167
Cdd:pfam00561   1 PPVLLLHG----LPGSSDLWRKLApalARDGFRVIALDLRGFGKSSRPKAQDDYRTDDLAEDLeYILEALGL--EKVNLV 74
                          90       100       110
                  ....*....|....*....|....*....|...
gi 564333158  168 GQSIGTVPSVDLAARYES--AAVILHSPLTSGM 198
Cdd:pfam00561  75 GHSMGGLIALAYAAKYPDrvKALVLLGALDPPH 107
UPF0227 pfam05728
Uncharacterized protein family (UPF0227); Despite being classed as uncharacterized proteins, ...
159-280 2.87e-04

Uncharacterized protein family (UPF0227); Despite being classed as uncharacterized proteins, the members of this family are almost certainly enzymes that are distantly related to the pfam00561.


Pssm-ID: 283403 [Multi-domain]  Cd Length: 187  Bit Score: 40.86  E-value: 2.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  159 IRPENVIIYGQSIGTVPSVDLAARYESAAVIL------HSPLTSGM-RVAFPDTKKTYCFDAFPNID----KISKITSPV 227
Cdd:pfam05728  56 LGDDNPLLVGSSLGGYYATWLGFRCGLRQVLFnpavrpYENLAGKLgEQANPYTGQTYVLEEYHDIElkclEVFRLKNPD 135
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 564333158  228 --LIIHGTEDEVIDFSHGLALFERCQRPVEplwvEGAGH--NDVElygQYLERLKQF 280
Cdd:pfam05728 136 rcLVLLQKGDEVLDYRRAAAHYRPYYEIVW----DGGDHkfKDFS---RHLQQIKAF 185
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
94-190 5.97e-04

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 40.15  E-value: 5.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158   94 LLFSHGNAVDLGQMSSFyigLGSRINCniFSYDYSGYGASSGKPTEKNLYADVEAAWLALrtrygIRPENVIIYGQSIGT 173
Cdd:pfam12697   1 VVLVHGAGLSAAPLAAL---LAAGVAV--LAPDLPGHGSSSPPPLDLADLADLAALLDEL-----GAARPVVLVGHSLGG 70
                          90
                  ....*....|....*..
gi 564333158  174 VPSVDLAARYESAAVIL 190
Cdd:pfam12697  71 AVALAAAAAALVVGVLV 87
Abhydrolase_2 pfam02230
Phospholipase/Carboxylesterase; This family consists of both phospholipases and ...
157-282 9.94e-04

Phospholipase/Carboxylesterase; This family consists of both phospholipases and carboxylesterases with broad substrate specificity, and is structurally related to alpha/beta hydrolases pfam00561.


Pssm-ID: 396693 [Multi-domain]  Cd Length: 217  Bit Score: 39.67  E-value: 9.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564333158  157 YGIRPENVIIYGQSIGtvpsvdlaaryesAAVILHSPLTSGMR----VAF-----PDTKktycfdaFPNIDKISKITSPV 227
Cdd:pfam02230 100 KGIPSSRIIIGGFSQG-------------AMLALYSALTLPLPlggiVAFsgflpLPTK-------FPSHPNLVTKKTPI 159
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 564333158  228 LIIHGTEDEVIDFSHGLALFER---CQRPVEPLWVEGAGHndvELYGQYLERLKQFVS 282
Cdd:pfam02230 160 FLIHGEEDPVVPLALGKLAKEYlktSLNKVELKIYEGLAH---SICGREMQDIKKFLS 214
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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