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histone deacetylase complex subunit SAP130 isoform X1 [Homo sapiens]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
SAP130_C
pfam16014 Histone deacetylase complex subunit SAP130 C-terminus;
660-1065
0e+00
Histone deacetylase complex subunit SAP130 C-terminus;
Pssm-ID: 464973 [Multi-domain]
Cd Length: 371
Bit Score: 556.47
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 660 A Q GSSPRPSILRKKPAT D G mavrktlippqppdvasprvessmrstsgsprpag AKPK SE IHV SM A T PVTV SM E TVSN QN 739
Cdd:pfam16014 1 A L GSSPRPSILRKKPAT E G ----------------------------------- AKPK PD IHV AV A P PVTV AV E ALPG QN 45
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 740 ND Q P T IAVP P TA Q Q P PPT IPT MI A A A S PPSQP A V A LST I P G A VPI TPPI T --- TIAA APP PSVTVGGSLSSVLGPPV PEI 816
Cdd:pfam16014 46 SE Q Q T ASAS P PS Q H P AQA IPT IL A P A A PPSQP S V V LST L P A A MAV TPPI P asm ANVV APP TQPAASSTAACAVSSVL PEI 125
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 817 K V K E E V EPMD IMR pvs A VPPL ATNTV SP S L AL LANNLS M P TS DL P PGASPRKKPRKQQHVISTEEG D MMETNSTD D EKS T 896
Cdd:pfam16014 126 K I K Q E A EPMD TSQ --- S VPPL TPTSI SP A L TS LANNLS V P AG DL L PGASPRKKPRKQQHVISTEEG E MMETNSTD E EKS A 202
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 897 A K S L LVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK AM LQ EI ANQKGV S CR 976
Cdd:pfam16014 203 P K P L TSR AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK GT LQ DM ANQKGV T CR 282
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 977 AQGWK V HLCAAQLLQLTNLEHDVY E RLT N LQEG I IPKKKA A TDDDLHRINELIQGNMQRCKLVMDQI S EARDSM L KVLDH 1056
Cdd:pfam16014 283 AQGWK I HLCAAQLLQLTNLEHDVY S RLT T LQEG L IPKKKA G TDDDLHRINELIQGNMQRCKLVMDQI T EARDSM M KVLDH 362
....*....
gi 530369399 1057 KDRVLKLLN 1065
Cdd:pfam16014 363 KDRVLKLLN 371
Atrophin-1 super family
cl38111 Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
465-846
8.24e-05
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
pfam03154 :Pssm-ID: 460830 [Multi-domain]
Cd Length: 991
Bit Score: 46.68
E-value: 8.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 465 P N P VAM E TR SD NRPSVPVQFQYFLPTYPP S AYPLAAHTYT P I T SSVS T IRQY P VSAQA P NSAIT A QTGVGVASTVHLN P M 544
Cdd:pfam03154 149 P S P QDN E SD SD SSAQQQILQTQPPVLQAQ S GAASPPSPPP P G T TQAA T AGPT P SAPSV P PQGSP A TSQPPNQTQSTAA P H 228
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 545 Q L MTVDAS ha R H I Q GI q P A P ISTQGIQPA P IGTPGIQ P A PL GTQGI H SAT P INTQG LQ PA P MGT Q Q P Q P E gktsavvlad 624
Cdd:pfam03154 229 T L IQQTPT -- L H P Q RL - P S P HPPLQPMTQ P PPPSQVS P Q PL PQPSL H GQM P PMPHS LQ TG P SHM Q H P V P P ---------- 295
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 625 g ATIVAN P I S NPFSAA P AATTVVQTH SQ SASTNA P A Q GSSPRPSIL R KK P ATDGMAVRKTLI PP --------------- Q 689
Cdd:pfam03154 296 - QPFPLT P Q S SQSQVP P GPSPAAPGQ SQ QRIHTP P S Q SQLQSQQPP R EQ P LPPAPLSMPHIK PP pttpipqlpnpqshk H 374
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 690 PP DVAS P rve S SMRST S GS P R P AGA KP K S EI --- H VSM A T P VTVSMETV S N Q ---- NNDQ P TIAVPPTAQQ P PPTI P TMI 762
Cdd:pfam03154 375 PP HLSG P --- S PFQMN S NL P P P PAL KP L S SL sth H PPS A H P PPLQLMPQ S Q Q lppp PAQP P VLTQSQSLPP P AASH P PTS 451
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 763 AAASP PSQ PAVAL - STI PG AV P - ITPP ITTIAAAPP ---------- P SV TVG G SLSSVLGP P V P EIKV KEE v EPMDIMR P 830
Cdd:pfam03154 452 GLHQV PSQ SPFPQ h PFV PG GP P p ITPP SGPPTSTSS ampgiqppss A SV SSS G PVPAAVSC P L P PVQI KEE - ALDEAEE P 530
410
....*....|....*.
gi 530369399 831 V S AV PP LATNTVS P SL 846
Cdd:pfam03154 531 E S PP PP PRSPSPE P TV 546
PHA03247 super family
cl33720 large tegument protein UL36; Provisional
45-422
2.67e-04
large tegument protein UL36; Provisional
PHA03247 :Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 45.31
E-value: 2.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 45 A PS QIANSGSAGLIN P AATVND E SG RD SEVSA R EHMSSSSSLQS R EEKQEPVVV RP YPQVQMLSTHHAVAS A T P VAVTAP 124
Cdd:PHA03247 2628 P PS PSPAANEPDPHP P PTVPPP E RP RD DPAPG R VSRPRRARRLG R AAQASSPPQ RP RRRAARPTVGSLTSL A D P PPPPPT 2707
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 125 P AHLTP A VPLSFSEGLMKPPPKPTM P SR P I APAPP STLS l P P KV PG QVTVTMESSIPQASAI P VATISGQQ G H P SN L HHI 204
Cdd:PHA03247 2708 P EPAPH A LVSATPLPPGPAAARQAS P AL P A APAPP AVPA - G P AT PG GPARPARPPTTAGPPA P APPAAPAA G P P RR L TRP 2786
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 205 MTTNVQM S IIRSNA P GP P LHIG A SH L PR gaaaaavms SSKVTTVLR P TSQ LP NAAT AQP AVQHIIHQ P IQSRP P VTT S N A 284
Cdd:PHA03247 2787 AVASLSE S RESLPS P WD P ADPP A AV L AP --------- AAALPPAAS P AGP LP PPTS AQP TAPPPPPG P PPPSL P LGG S V A 2857
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 285 -------- I P PAVV A TVS A TR A QS PV ITTTA --- AHA T D S ALR P TLSIQH PP SAAISIQRPA Q SRDVTTRITL P SH P ALG 353
Cdd:PHA03247 2858 pggdvrrr P P SRSP A AKP A AP A RP PV RRLAR pav SRS T E S FAL P PDQPER PP QPQAPPPPQP Q PQPPPPPQPQ P PP P PPP 2937
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530369399 354 T P KQQ L HTMAQKTIFSTGTPVAAATVAPI L ATNTIP ----- SATT A G S VSHTQAP T STIVTMTVPSH SS H A TAV 422
Cdd:PHA03247 2938 R P QPP L APTTDPAGAGEPSGAVPQPWLGA L VPGRVA vprfr VPQP A P S REAPASS T PPLTGHSLSRV SS W A SSL 3011
Name
Accession
Description
Interval
E-value
SAP130_C
pfam16014 Histone deacetylase complex subunit SAP130 C-terminus;
660-1065
0e+00
Histone deacetylase complex subunit SAP130 C-terminus;
Pssm-ID: 464973 [Multi-domain]
Cd Length: 371
Bit Score: 556.47
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 660 A Q GSSPRPSILRKKPAT D G mavrktlippqppdvasprvessmrstsgsprpag AKPK SE IHV SM A T PVTV SM E TVSN QN 739
Cdd:pfam16014 1 A L GSSPRPSILRKKPAT E G ----------------------------------- AKPK PD IHV AV A P PVTV AV E ALPG QN 45
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 740 ND Q P T IAVP P TA Q Q P PPT IPT MI A A A S PPSQP A V A LST I P G A VPI TPPI T --- TIAA APP PSVTVGGSLSSVLGPPV PEI 816
Cdd:pfam16014 46 SE Q Q T ASAS P PS Q H P AQA IPT IL A P A A PPSQP S V V LST L P A A MAV TPPI P asm ANVV APP TQPAASSTAACAVSSVL PEI 125
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 817 K V K E E V EPMD IMR pvs A VPPL ATNTV SP S L AL LANNLS M P TS DL P PGASPRKKPRKQQHVISTEEG D MMETNSTD D EKS T 896
Cdd:pfam16014 126 K I K Q E A EPMD TSQ --- S VPPL TPTSI SP A L TS LANNLS V P AG DL L PGASPRKKPRKQQHVISTEEG E MMETNSTD E EKS A 202
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 897 A K S L LVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK AM LQ EI ANQKGV S CR 976
Cdd:pfam16014 203 P K P L TSR AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK GT LQ DM ANQKGV T CR 282
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 977 AQGWK V HLCAAQLLQLTNLEHDVY E RLT N LQEG I IPKKKA A TDDDLHRINELIQGNMQRCKLVMDQI S EARDSM L KVLDH 1056
Cdd:pfam16014 283 AQGWK I HLCAAQLLQLTNLEHDVY S RLT T LQEG L IPKKKA G TDDDLHRINELIQGNMQRCKLVMDQI T EARDSM M KVLDH 362
....*....
gi 530369399 1057 KDRVLKLLN 1065
Cdd:pfam16014 363 KDRVLKLLN 371
PHA03247
PHA03247 large tegument protein UL36; Provisional
562-911
3.47e-07
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 54.94
E-value: 3.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 562 P A P ISTQGIQ PA PIGT P GIQPA P L G T qgihs ATP I -- NTQGLQ P APM G TQQ P Q P ----- E G KTSAVVLADG A TIVANPI S 634
Cdd:PHA03247 2723 P G P AAARQAS PA LPAA P APPAV P A G P ----- ATP G gp ARPARP P TTA G PPA P A P paapa A G PPRRLTRPAV A SLSESRE S 2797
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 635 N P FSAA PA ATTVVQTHSQS A -- STNA PA QGSS P RP S ILRKK P AT dgmavrk TLI PP Q P PDV ---- AS P RVESSM R ST S G S 708
Cdd:PHA03247 2798 L P SPWD PA DPPAAVLAPAA A lp PAAS PA GPLP P PT S AQPTA P PP ------- PPG PP P P SLP lggs VA P GGDVRR R PP S R S 2870
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 709 P RPAG A K P KSEIHVSM A T P VT vsme TV S NQNNDQ P TIAVPPTA Q QPP P TI P TMIAAAS PP S QP AVALSTI P GAV P ITP P I 788
Cdd:PHA03247 2871 P AAKP A A P ARPPVRRL A R P AV ---- SR S TESFAL P PDQPERPP Q PQA P PP P QPQPQPP PP P QP QPPPPPP P RPQ P PLA P T 2946
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 789 T TI A A A PP PS VT V GGSLSSV L G P --- P VP EIK V KEEVEPMDI mr P V S AV PPL a T NTVSPSLALL A NN L SMPTSDL PP GA S 865
Cdd:PHA03247 2947 T DP A G A GE PS GA V PQPWLGA L V P grv A VP RFR V PQPAPSREA -- P A S ST PPL - T GHSLSRVSSW A SS L ALHEETD PP PV S 3023
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 530369399 866 prkkp R KQ QHVIS -- TE EG D MMETNST D D E K S TAKS L LVKAEKRKS P P 911
Cdd:PHA03247 3024 ----- L KQ TLWPP dd TE DS D ADSLFDS D S E R S DLEA L DPLPPEPHD P F 3066
Atrophin-1
pfam03154 Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
465-846
8.24e-05
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain]
Cd Length: 991
Bit Score: 46.68
E-value: 8.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 465 P N P VAM E TR SD NRPSVPVQFQYFLPTYPP S AYPLAAHTYT P I T SSVS T IRQY P VSAQA P NSAIT A QTGVGVASTVHLN P M 544
Cdd:pfam03154 149 P S P QDN E SD SD SSAQQQILQTQPPVLQAQ S GAASPPSPPP P G T TQAA T AGPT P SAPSV P PQGSP A TSQPPNQTQSTAA P H 228
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 545 Q L MTVDAS ha R H I Q GI q P A P ISTQGIQPA P IGTPGIQ P A PL GTQGI H SAT P INTQG LQ PA P MGT Q Q P Q P E gktsavvlad 624
Cdd:pfam03154 229 T L IQQTPT -- L H P Q RL - P S P HPPLQPMTQ P PPPSQVS P Q PL PQPSL H GQM P PMPHS LQ TG P SHM Q H P V P P ---------- 295
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 625 g ATIVAN P I S NPFSAA P AATTVVQTH SQ SASTNA P A Q GSSPRPSIL R KK P ATDGMAVRKTLI PP --------------- Q 689
Cdd:pfam03154 296 - QPFPLT P Q S SQSQVP P GPSPAAPGQ SQ QRIHTP P S Q SQLQSQQPP R EQ P LPPAPLSMPHIK PP pttpipqlpnpqshk H 374
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 690 PP DVAS P rve S SMRST S GS P R P AGA KP K S EI --- H VSM A T P VTVSMETV S N Q ---- NNDQ P TIAVPPTAQQ P PPTI P TMI 762
Cdd:pfam03154 375 PP HLSG P --- S PFQMN S NL P P P PAL KP L S SL sth H PPS A H P PPLQLMPQ S Q Q lppp PAQP P VLTQSQSLPP P AASH P PTS 451
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 763 AAASP PSQ PAVAL - STI PG AV P - ITPP ITTIAAAPP ---------- P SV TVG G SLSSVLGP P V P EIKV KEE v EPMDIMR P 830
Cdd:pfam03154 452 GLHQV PSQ SPFPQ h PFV PG GP P p ITPP SGPPTSTSS ampgiqppss A SV SSS G PVPAAVSC P L P PVQI KEE - ALDEAEE P 530
410
....*....|....*.
gi 530369399 831 V S AV PP LATNTVS P SL 846
Cdd:pfam03154 531 E S PP PP PRSPSPE P TV 546
PHA03247
PHA03247 large tegument protein UL36; Provisional
45-422
2.67e-04
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 45.31
E-value: 2.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 45 A PS QIANSGSAGLIN P AATVND E SG RD SEVSA R EHMSSSSSLQS R EEKQEPVVV RP YPQVQMLSTHHAVAS A T P VAVTAP 124
Cdd:PHA03247 2628 P PS PSPAANEPDPHP P PTVPPP E RP RD DPAPG R VSRPRRARRLG R AAQASSPPQ RP RRRAARPTVGSLTSL A D P PPPPPT 2707
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 125 P AHLTP A VPLSFSEGLMKPPPKPTM P SR P I APAPP STLS l P P KV PG QVTVTMESSIPQASAI P VATISGQQ G H P SN L HHI 204
Cdd:PHA03247 2708 P EPAPH A LVSATPLPPGPAAARQAS P AL P A APAPP AVPA - G P AT PG GPARPARPPTTAGPPA P APPAAPAA G P P RR L TRP 2786
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 205 MTTNVQM S IIRSNA P GP P LHIG A SH L PR gaaaaavms SSKVTTVLR P TSQ LP NAAT AQP AVQHIIHQ P IQSRP P VTT S N A 284
Cdd:PHA03247 2787 AVASLSE S RESLPS P WD P ADPP A AV L AP --------- AAALPPAAS P AGP LP PPTS AQP TAPPPPPG P PPPSL P LGG S V A 2857
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 285 -------- I P PAVV A TVS A TR A QS PV ITTTA --- AHA T D S ALR P TLSIQH PP SAAISIQRPA Q SRDVTTRITL P SH P ALG 353
Cdd:PHA03247 2858 pggdvrrr P P SRSP A AKP A AP A RP PV RRLAR pav SRS T E S FAL P PDQPER PP QPQAPPPPQP Q PQPPPPPQPQ P PP P PPP 2937
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530369399 354 T P KQQ L HTMAQKTIFSTGTPVAAATVAPI L ATNTIP ----- SATT A G S VSHTQAP T STIVTMTVPSH SS H A TAV 422
Cdd:PHA03247 2938 R P QPP L APTTDPAGAGEPSGAVPQPWLGA L VPGRVA vprfr VPQP A P S REAPASS T PPLTGHSLSRV SS W A SSL 3011
PRK07764
PRK07764 DNA polymerase III subunits gamma and tau; Validated
276-682
1.75e-03
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain]
Cd Length: 824
Bit Score: 42.28
E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 276 R PPVTTSN A IP PA VV A TVS A TR A QSPVITTT AA HATDS A LRPTLSIQH P PS A AISIQR P AQSRDVTTRITL PS H P ALGT P 355
Cdd:PRK07764 383 R RLGVAGG A GA PA AA A PSA A AA A PAAAPAPA AA APAAA A APAPAAAPQ P AP A PAPAPA P PSPAGNAPAGGA PS P P PAAA P 462
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 356 KQ Q LHTMAQKTIFS T GT P VA A ATV AP il A TNTI P S A TT A GSVSHTQAPTS T I ------ VTMT VP SH S SHAT A VTTSNIP V 429
Cdd:PRK07764 463 SA Q PAPAPAAAPEP T AA P AP A PPA AP -- A PAAA P A A PA A PAAPAGADDAA T L rerwpe ILAA VP KR S RKTW A ILLPEAT V 540
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 430 AK V VPQQ -- ITHTSP ---- R I - Q P DYPAE - RSS L IPIS G HRASPNP V AMETRSDNRPSV P VQFQYFL P TYP --- P S A YPL 498
Cdd:PRK07764 541 LG V RGDT lv LGFSTG glar R F a S P GNAEV l VTA L AEEL G GDWQVEA V VGPAPGAAGGEG P PAPASSG P PEE aar P A A PAA 620
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 499 A A HTYT P ITSSVSTIRQYPVS A Q AP NS A ITAQTGVG VA ST vhl NPMQLMTVDASH A RHIQGIQ P A P ISTQGIQP AP I G TP 578
Cdd:PRK07764 621 P A APAA P APAGAAAAPAEASA A P AP GV A APEHHPKH VA VP --- DASDGGDGWPAK A GGAAPAA P P P APAPAAPA AP A G AA 697
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 579 GI QPAP LGTQGIHSATPINTQGLQ P APMGTQQPQPEGKTSA V V L ADGAT iv AN P ISNPFS A A P AATTVVQTHSQS A STNA 658
Cdd:PRK07764 698 PA QPAP APAATPPAGQADDPAAQP P QAAQGASAPSPAADDP V P L PPEPD -- DP P DPAGAP A Q P PPPPAPAPAAAP A AAPP 775
410 420
....*....|....*....|....
gi 530369399 659 P AQG S SPRPSILRKK P AT D GMAV R 682
Cdd:PRK07764 776 P SPP S EEEEMAEDDA P SM D DEDR R 799
Name
Accession
Description
Interval
E-value
SAP130_C
pfam16014 Histone deacetylase complex subunit SAP130 C-terminus;
660-1065
0e+00
Histone deacetylase complex subunit SAP130 C-terminus;
Pssm-ID: 464973 [Multi-domain]
Cd Length: 371
Bit Score: 556.47
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 660 A Q GSSPRPSILRKKPAT D G mavrktlippqppdvasprvessmrstsgsprpag AKPK SE IHV SM A T PVTV SM E TVSN QN 739
Cdd:pfam16014 1 A L GSSPRPSILRKKPAT E G ----------------------------------- AKPK PD IHV AV A P PVTV AV E ALPG QN 45
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 740 ND Q P T IAVP P TA Q Q P PPT IPT MI A A A S PPSQP A V A LST I P G A VPI TPPI T --- TIAA APP PSVTVGGSLSSVLGPPV PEI 816
Cdd:pfam16014 46 SE Q Q T ASAS P PS Q H P AQA IPT IL A P A A PPSQP S V V LST L P A A MAV TPPI P asm ANVV APP TQPAASSTAACAVSSVL PEI 125
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 817 K V K E E V EPMD IMR pvs A VPPL ATNTV SP S L AL LANNLS M P TS DL P PGASPRKKPRKQQHVISTEEG D MMETNSTD D EKS T 896
Cdd:pfam16014 126 K I K Q E A EPMD TSQ --- S VPPL TPTSI SP A L TS LANNLS V P AG DL L PGASPRKKPRKQQHVISTEEG E MMETNSTD E EKS A 202
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 897 A K S L LVK AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK AM LQ EI ANQKGV S CR 976
Cdd:pfam16014 203 P K P L TSR AEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEEKK GT LQ DM ANQKGV T CR 282
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 977 AQGWK V HLCAAQLLQLTNLEHDVY E RLT N LQEG I IPKKKA A TDDDLHRINELIQGNMQRCKLVMDQI S EARDSM L KVLDH 1056
Cdd:pfam16014 283 AQGWK I HLCAAQLLQLTNLEHDVY S RLT T LQEG L IPKKKA G TDDDLHRINELIQGNMQRCKLVMDQI T EARDSM M KVLDH 362
....*....
gi 530369399 1057 KDRVLKLLN 1065
Cdd:pfam16014 363 KDRVLKLLN 371
PHA03247
PHA03247 large tegument protein UL36; Provisional
562-911
3.47e-07
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 54.94
E-value: 3.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 562 P A P ISTQGIQ PA PIGT P GIQPA P L G T qgihs ATP I -- NTQGLQ P APM G TQQ P Q P ----- E G KTSAVVLADG A TIVANPI S 634
Cdd:PHA03247 2723 P G P AAARQAS PA LPAA P APPAV P A G P ----- ATP G gp ARPARP P TTA G PPA P A P paapa A G PPRRLTRPAV A SLSESRE S 2797
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 635 N P FSAA PA ATTVVQTHSQS A -- STNA PA QGSS P RP S ILRKK P AT dgmavrk TLI PP Q P PDV ---- AS P RVESSM R ST S G S 708
Cdd:PHA03247 2798 L P SPWD PA DPPAAVLAPAA A lp PAAS PA GPLP P PT S AQPTA P PP ------- PPG PP P P SLP lggs VA P GGDVRR R PP S R S 2870
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 709 P RPAG A K P KSEIHVSM A T P VT vsme TV S NQNNDQ P TIAVPPTA Q QPP P TI P TMIAAAS PP S QP AVALSTI P GAV P ITP P I 788
Cdd:PHA03247 2871 P AAKP A A P ARPPVRRL A R P AV ---- SR S TESFAL P PDQPERPP Q PQA P PP P QPQPQPP PP P QP QPPPPPP P RPQ P PLA P T 2946
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 789 T TI A A A PP PS VT V GGSLSSV L G P --- P VP EIK V KEEVEPMDI mr P V S AV PPL a T NTVSPSLALL A NN L SMPTSDL PP GA S 865
Cdd:PHA03247 2947 T DP A G A GE PS GA V PQPWLGA L V P grv A VP RFR V PQPAPSREA -- P A S ST PPL - T GHSLSRVSSW A SS L ALHEETD PP PV S 3023
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 530369399 866 prkkp R KQ QHVIS -- TE EG D MMETNST D D E K S TAKS L LVKAEKRKS P P 911
Cdd:PHA03247 3024 ----- L KQ TLWPP dd TE DS D ADSLFDS D S E R S DLEA L DPLPPEPHD P F 3066
PHA03247
PHA03247 large tegument protein UL36; Provisional
652-870
4.47e-06
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 51.09
E-value: 4.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 652 QSASTNA P AQGSS P R P SILRKK PA TD --- GMAVRKTLI P PQ P P D VAS P RVE S SM R STSGSP R P A G A KPKSEIHVSM A TPV 728
Cdd:PHA03247 2611 PAPPSPL P PDTHA P D P PPPSPS PA AN epd PHPPPTVPP P ER P R D DPA P GRV S RP R RARRLG R A A Q A SSPPQRPRRR A ARP 2690
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 729 TV SME T VSNQNNDQ P ------------ TIAV PP TAQQPPPTI P TMI AA AS PP SQ PA VALSTIPG A V P IT PP I T TIAA AP - 795
Cdd:PHA03247 2691 TV GSL T SLADPPPP P ptpepaphalvs ATPL PP GPAAARQAS P ALP AA PA PP AV PA GPATPGGP A R P AR PP T T AGPP AP a 2770
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530369399 796 PP SVTVG G SLSSVLG P P V PEIKVKE E VE P MDIMRPVSAVPP LA TNTVS P SL A LL A NN L SM PTS DL P PGAS P RKK P 870
Cdd:PHA03247 2771 PP AAPAA G PPRRLTR P A V ASLSESR E SL P SPWDPADPPAAV LA PAAAL P PA A SP A GP L PP PTS AQ P TAPP P PPG P 2845
Atrophin-1
pfam03154 Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ...
465-846
8.24e-05
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain]
Cd Length: 991
Bit Score: 46.68
E-value: 8.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 465 P N P VAM E TR SD NRPSVPVQFQYFLPTYPP S AYPLAAHTYT P I T SSVS T IRQY P VSAQA P NSAIT A QTGVGVASTVHLN P M 544
Cdd:pfam03154 149 P S P QDN E SD SD SSAQQQILQTQPPVLQAQ S GAASPPSPPP P G T TQAA T AGPT P SAPSV P PQGSP A TSQPPNQTQSTAA P H 228
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 545 Q L MTVDAS ha R H I Q GI q P A P ISTQGIQPA P IGTPGIQ P A PL GTQGI H SAT P INTQG LQ PA P MGT Q Q P Q P E gktsavvlad 624
Cdd:pfam03154 229 T L IQQTPT -- L H P Q RL - P S P HPPLQPMTQ P PPPSQVS P Q PL PQPSL H GQM P PMPHS LQ TG P SHM Q H P V P P ---------- 295
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 625 g ATIVAN P I S NPFSAA P AATTVVQTH SQ SASTNA P A Q GSSPRPSIL R KK P ATDGMAVRKTLI PP --------------- Q 689
Cdd:pfam03154 296 - QPFPLT P Q S SQSQVP P GPSPAAPGQ SQ QRIHTP P S Q SQLQSQQPP R EQ P LPPAPLSMPHIK PP pttpipqlpnpqshk H 374
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 690 PP DVAS P rve S SMRST S GS P R P AGA KP K S EI --- H VSM A T P VTVSMETV S N Q ---- NNDQ P TIAVPPTAQQ P PPTI P TMI 762
Cdd:pfam03154 375 PP HLSG P --- S PFQMN S NL P P P PAL KP L S SL sth H PPS A H P PPLQLMPQ S Q Q lppp PAQP P VLTQSQSLPP P AASH P PTS 451
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 763 AAASP PSQ PAVAL - STI PG AV P - ITPP ITTIAAAPP ---------- P SV TVG G SLSSVLGP P V P EIKV KEE v EPMDIMR P 830
Cdd:pfam03154 452 GLHQV PSQ SPFPQ h PFV PG GP P p ITPP SGPPTSTSS ampgiqppss A SV SSS G PVPAAVSC P L P PVQI KEE - ALDEAEE P 530
410
....*....|....*.
gi 530369399 831 V S AV PP LATNTVS P SL 846
Cdd:pfam03154 531 E S PP PP PRSPSPE P TV 546
PHA03247
PHA03247 large tegument protein UL36; Provisional
45-422
2.67e-04
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 45.31
E-value: 2.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 45 A PS QIANSGSAGLIN P AATVND E SG RD SEVSA R EHMSSSSSLQS R EEKQEPVVV RP YPQVQMLSTHHAVAS A T P VAVTAP 124
Cdd:PHA03247 2628 P PS PSPAANEPDPHP P PTVPPP E RP RD DPAPG R VSRPRRARRLG R AAQASSPPQ RP RRRAARPTVGSLTSL A D P PPPPPT 2707
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 125 P AHLTP A VPLSFSEGLMKPPPKPTM P SR P I APAPP STLS l P P KV PG QVTVTMESSIPQASAI P VATISGQQ G H P SN L HHI 204
Cdd:PHA03247 2708 P EPAPH A LVSATPLPPGPAAARQAS P AL P A APAPP AVPA - G P AT PG GPARPARPPTTAGPPA P APPAAPAA G P P RR L TRP 2786
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 205 MTTNVQM S IIRSNA P GP P LHIG A SH L PR gaaaaavms SSKVTTVLR P TSQ LP NAAT AQP AVQHIIHQ P IQSRP P VTT S N A 284
Cdd:PHA03247 2787 AVASLSE S RESLPS P WD P ADPP A AV L AP --------- AAALPPAAS P AGP LP PPTS AQP TAPPPPPG P PPPSL P LGG S V A 2857
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 285 -------- I P PAVV A TVS A TR A QS PV ITTTA --- AHA T D S ALR P TLSIQH PP SAAISIQRPA Q SRDVTTRITL P SH P ALG 353
Cdd:PHA03247 2858 pggdvrrr P P SRSP A AKP A AP A RP PV RRLAR pav SRS T E S FAL P PDQPER PP QPQAPPPPQP Q PQPPPPPQPQ P PP P PPP 2937
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530369399 354 T P KQQ L HTMAQKTIFSTGTPVAAATVAPI L ATNTIP ----- SATT A G S VSHTQAP T STIVTMTVPSH SS H A TAV 422
Cdd:PHA03247 2938 R P QPP L APTTDPAGAGEPSGAVPQPWLGA L VPGRVA vprfr VPQP A P S REAPASS T PPLTGHSLSRV SS W A SSL 3011
PHA03247
PHA03247 large tegument protein UL36; Provisional
124-517
3.18e-04
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain]
Cd Length: 3151
Bit Score: 44.93
E-value: 3.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 124 PP AH L T PA --------- VP LSFSEGLMKP P PKPTMPS RP I AP APPSTLSL P PKVP G QVTVTMES S - I P QASAI P VATISG 193
Cdd:PHA03247 2551 PP PP L P PA appaapdrs VP PPRPAPRPSE P AVTSRAR RP D AP PQSARPRA P VDDR G DPRGPAPP S p L P PDTHA P DPPPPS 2630
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 194 QQGHPSNLHHIMTTN V QMSIIRSNA P G P P ------------ LHIG AS HL P RGAAAA A VMSS - SKV T TVLR P TSQL P NAAT 260
Cdd:PHA03247 2631 PSPAANEPDPHPPPT V PPPERPRDD P A P G rvsrprrarrlg RAAQ AS SP P QRPRRR A ARPT v GSL T SLAD P PPPP P TPEP 2710
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 261 A QP A VQHIIHQ P I ------ Q SR P PVTTSN A I P PAVVATV --- SAT R AQS P VI T TTAAHATDS A LRPT lsiq H PP SAA isi 331
Cdd:PHA03247 2711 A PH A LVSATPL P P gpaaar Q AS P ALPAAP A P P AVPAGPA tpg GPA R PAR P PT T AGPPAPAPP A APAA ---- G PP RRL --- 2783
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 332 Q RPA QSRDVTT R IT LPS ------ H PA LGTPKQQLHTM A QKTIFSTGT P VA A ATV AP ILATNTI P SATTA G SVSHTQAP ts 405
Cdd:PHA03247 2784 T RPA VASLSES R ES LPS pwdpad P PA AVLAPAAALPP A ASPAGPLPP P TS A QPT AP PPPPGPP P PSLPL G GSVAPGGD -- 2861
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 406 ti V TMTV PS H S SH A TAVTTSNI PV AKV vpqqithts P R IQPDYPA E RSS L I P ISGH R ASPNPVAMETRSDNR P SV P V Q F Q 485
Cdd:PHA03247 2862 -- V RRRP PS R S PA A KPAAPARP PV RRL --------- A R PAVSRST E SFA L P P DQPE R PPQPQAPPPPQPQPQ P PP P P Q P Q 2930
410 420 430
....*....|....*....|....*....|..
gi 530369399 486 YFL P TY P PSAY PLA AH T YTPITSSV S TIRQY P 517
Cdd:PHA03247 2931 PPP P PP P RPQP PLA PT T DPAGAGEP S GAVPQ P 2962
PRK07764
PRK07764 DNA polymerase III subunits gamma and tau; Validated
276-682
1.75e-03
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain]
Cd Length: 824
Bit Score: 42.28
E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 276 R PPVTTSN A IP PA VV A TVS A TR A QSPVITTT AA HATDS A LRPTLSIQH P PS A AISIQR P AQSRDVTTRITL PS H P ALGT P 355
Cdd:PRK07764 383 R RLGVAGG A GA PA AA A PSA A AA A PAAAPAPA AA APAAA A APAPAAAPQ P AP A PAPAPA P PSPAGNAPAGGA PS P P PAAA P 462
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 356 KQ Q LHTMAQKTIFS T GT P VA A ATV AP il A TNTI P S A TT A GSVSHTQAPTS T I ------ VTMT VP SH S SHAT A VTTSNIP V 429
Cdd:PRK07764 463 SA Q PAPAPAAAPEP T AA P AP A PPA AP -- A PAAA P A A PA A PAAPAGADDAA T L rerwpe ILAA VP KR S RKTW A ILLPEAT V 540
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 430 AK V VPQQ -- ITHTSP ---- R I - Q P DYPAE - RSS L IPIS G HRASPNP V AMETRSDNRPSV P VQFQYFL P TYP --- P S A YPL 498
Cdd:PRK07764 541 LG V RGDT lv LGFSTG glar R F a S P GNAEV l VTA L AEEL G GDWQVEA V VGPAPGAAGGEG P PAPASSG P PEE aar P A A PAA 620
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 499 A A HTYT P ITSSVSTIRQYPVS A Q AP NS A ITAQTGVG VA ST vhl NPMQLMTVDASH A RHIQGIQ P A P ISTQGIQP AP I G TP 578
Cdd:PRK07764 621 P A APAA P APAGAAAAPAEASA A P AP GV A APEHHPKH VA VP --- DASDGGDGWPAK A GGAAPAA P P P APAPAAPA AP A G AA 697
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 579 GI QPAP LGTQGIHSATPINTQGLQ P APMGTQQPQPEGKTSA V V L ADGAT iv AN P ISNPFS A A P AATTVVQTHSQS A STNA 658
Cdd:PRK07764 698 PA QPAP APAATPPAGQADDPAAQP P QAAQGASAPSPAADDP V P L PPEPD -- DP P DPAGAP A Q P PPPPAPAPAAAP A AAPP 775
410 420
....*....|....*....|....
gi 530369399 659 P AQG S SPRPSILRKK P AT D GMAV R 682
Cdd:PRK07764 776 P SPP S EEEEMAEDDA P SM D DEDR R 799
PTZ00449
PTZ00449 104 kDa microneme/rhoptry antigen; Provisional
655-889
3.98e-03
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain]
Cd Length: 943
Bit Score: 41.21
E-value: 3.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 655 S TNA P AQGS SP RPSI L RKK P ATDGMAVRKT -- LI PP Q P PDVA SP RVESSMRSTSGSPR P AGA KP ------ K SEIHVSMAT 726
Cdd:PTZ00449 602 S AQR P TRPK SP KLPE L LDI P KSPKRPESPK sp KR PP P P QRPS SP ERPEGPKIIKSPKP P KSP KP pfdpkf K EKFYDDYLD 681
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 727 PVTV S M ET VSNQNN D QPTIAVPPTAQQPP P TI P TMIAAAS PP SQ P AVALS tipgav P IT P PITTI A AA P PP svtvggsl S 806
Cdd:PTZ00449 682 AAAK S K ET KTTVVL D ESFESILKETLPET P GT P FTTPRPL PP KL P RDEEF ------ P FE P IGDPD A EQ P DD -------- I 747
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 807 SVLG PP VP E - IKVK E --- EVEPM DI MRPVSAVPPLATN T VS P SL A LLANNLSMPTS D L PPG --- AS P R K KP R KQQHVI ST 879
Cdd:PTZ00449 748 EFFT PP EE E r TFFH E tpa DTPLP DI LAEEFKEEDIHAE T GE P DE A MKRPDSPSEHE D K PPG dhp SL P K K RH R LDGLAL ST 827
250
....*....|
gi 530369399 880 EE gdm M E TNS 889
Cdd:PTZ00449 828 TD --- L E SDA 834
PRK07003
PRK07003 DNA polymerase III subunit gamma/tau;
581-804
7.73e-03
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain]
Cd Length: 830
Bit Score: 40.22
E-value: 7.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 581 Q PA PL G TQGIHSAT P INTQ G LQ PAP mgtqqpqpegkts AVVL A DGATIV A N P ISNPFSA A PA A TTVVQTHSQS A S T N A P A 660
Cdd:PRK07003 359 E PA VT G GGAPGGGV P ARVA G AV PAP ------------- GARA A AAVGAS A V P AVTAVTG A AG A ALAPKAAAAA A A T R A E A 425
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530369399 661 QGSS P R P silrkk PAT DGMAVRKTLIPPQP P DV A SP R VESSM R STSGSPR P A g A KPK S EIHVSMAT P VTVSM E tvsnqnn 740
Cdd:PRK07003 426 PPAA P A P ------ PAT ADRGDDAADGDAPV P AK A NA R ASADS R CDERDAQ P P - A DSG S ASAPASDA P PDAAF E ------- 491
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530369399 741 DQ P TI A V P PT A QQPPPTIPTMI AAAS PPSQ PA V A LSTI P G A V P I TP pitti AAA P P PSVTV G GS 804
Cdd:PRK07003 492 PA P RA A A P SA A TPAAVPDARAP AAAS REDA PA A A APPA P E A R P P TP ----- AAA A P AARAG G AA 550
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
