NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|530415365|ref|XP_005260214|]
View 

armadillo repeat-containing protein 6 isoform X4 [Homo sapiens]

Protein Classification

armadillo/beta-catenin-like repeat-containing protein( domain architecture ID 10640621)

armadillo/beta-catenin-like repeat-containing protein similar to catenin beta, plakophilin and armadillo repeat-containing protein

CATH:  1.25.10.10
Gene Ontology:  GO:0098609|GO:0005515
PubMed:  12946625|9770300|9298899|20688255
SCOP:  3000116

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 184-226 3.59e-04

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


:

Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 38.18  E-value: 3.59e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 530415365   184 HEQNRQDLVKAGVLPLLTGAITHHghHTDVVREACWALRVMTF 226
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSE--DEEVVKEAAWALSNLSS 41
 
Name Accession Description Interval E-value
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 184-226 3.59e-04

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 38.18  E-value: 3.59e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 530415365   184 HEQNRQDLVKAGVLPLLTGAITHHghHTDVVREACWALRVMTF 226
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSE--DEEVVKEAAWALSNLSS 41
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 184-222 1.77e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.89  E-value: 1.77e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 530415365  184 HEQNRQDLVKAGVLPLLTGAITHHghHTDVVREACWALR 222
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSP--DEEVQEEAAWALS 37
 
Name Accession Description Interval E-value
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 184-226 3.59e-04

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 38.18  E-value: 3.59e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 530415365   184 HEQNRQDLVKAGVLPLLTGAITHHghHTDVVREACWALRVMTF 226
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSE--DEEVVKEAAWALSNLSS 41
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 184-222 1.77e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.89  E-value: 1.77e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 530415365  184 HEQNRQDLVKAGVLPLLTGAITHHghHTDVVREACWALR 222
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSP--DEEVQEEAAWALS 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH