|
Name |
Accession |
Description |
Interval |
E-value |
| peroxidasin_like |
cd09826 |
Animal heme peroxidase domain of peroxidasin and related proteins; Peroxidasin is a secreted ... |
236-671 |
0e+00 |
|
Animal heme peroxidase domain of peroxidasin and related proteins; Peroxidasin is a secreted heme peroxidase which is involved in hydrogen peroxide metabolism and peroxidative reactions in the cardiovascular system. The domain co-occurs with extracellular matrix domains and may play a role in the formation of the extracellular matrix.
Pssm-ID: 188658 Cd Length: 440 Bit Score: 764.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 236 DPRGTHAPCMLFARSSPACASGRPSATVDSVYAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPwPPSG 315
Cdd:cd09826 4 DPRRRGHRCIEFVRSSAVCGSGSTSLLFNSVTPREQINQLTSYIDASNVYGSSDEEALELRDLASDRGLLRVGIV-SEAG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 316 KPLLPFSTGPPTECARQEQESP--CFLAGDHRANEHLALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAE 393
Cdd:cd09826 83 KPLLPFERDSPMDCRRDPNESPipCFLAGDHRANEQLGLTSMHTLWLREHNRIASELLELNPHWDGETIYHETRKIVGAQ 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 394 LQHITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKALFSP 473
Cdd:cd09826 163 MQHITYSHWLPKILGPVGMEMLGEYRGYNPNVNPSIANEFATAAFRFGHTLINPILFRLDEDFQPIPEGHLPLHKAFFAP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 474 SRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNF 553
Cdd:cd09826 243 YRLVNEGGIDPLLRGLFATAAKDRVPDQLLNTELTEKLFEMAHEVALDLAALNIQRGRDHGLPGYNDYRKFCNLSVAETF 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 554 EDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQL 633
Cdd:cd09826 323 EDLKNEIKNDDVREKLKRLYGHPGNIDLFVGGILEDLLPGARVGPTLACLLAEQFRRLRDGDRFWYENPGVFSPAQLTQI 402
|
410 420 430
....*....|....*....|....*....|....*...
gi 530388290 634 KQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSE 671
Cdd:cd09826 403 KKTSLARVLCDNGDNITRVQEDVFLVPGNPHGYVSCES 440
|
|
| An_peroxidase |
pfam03098 |
Animal haem peroxidase; |
112-657 |
0e+00 |
|
Animal haem peroxidase;
Pssm-ID: 460804 [Multi-domain] Cd Length: 531 Bit Score: 711.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 112 YRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGlpvgSRQPLPPPRLVATVWARAAAVTPDHSYTRMLMHW 191
Cdd:pfam03098 1 YRTIDGSCNNLKNPSWGAAGTPFARLLPPAYEDGVSAPRGSS----SGSPLPSPRLVSNKLFAGDSGIPDPNLTLLLMQW 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 192 GWFLEHDLDHTVPALSTARFSDGRPCSsvCTN-DPPCFPMNTRHADPR--GTHAPCMLFARSSPACASGRPsatvdsvya 268
Cdd:pfam03098 77 GQFIDHDLTLTPESTSPNGSSCDCCCP--PENlHPPCFPIPIPPDDPFfsPFGVRCMPFVRSAPGCGLGNP--------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 269 REQINQQTAYIDGSNVYGSSERESQALRDPSvpRGLLKTGFPwpPSGKPLLPFSTGPPTECaRQEQESPCFLAGDHRANE 348
Cdd:pfam03098 146 REQINQVTSFLDGSQVYGSSEETARSLRSFS--GGLLKVNRS--DDGKELLPFDPDGPCCC-NSSGGVPCFLAGDSRANE 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 349 HLALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTR----MLRGYRGYNPN 424
Cdd:pfam03098 221 NPGLTALHTLFLREHNRIADELAKLNPHWSDETLFQEARKIVIAQIQHITYNEWLPAILGEDNMNwfglLPLPYNGYDPN 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 425 VNAGIINSFATAAFRFGHTLINPILYRLNATlGEISEGHLPFHKALFSPSRIIkEGGIDPVLRGLFGVAAKWRAPSYllS 504
Cdd:pfam03098 301 VDPSISNEFATAAFRFGHSLIPPFLYRLDEN-NVPEEPSLRLHDSFFNPDRLY-EGGIDPLLRGLATQPAQAVDNNF--T 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 505 PELTQRLFS-AAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIrQKLRKLYGSPGDIDLWP 583
Cdd:pfam03098 377 EELTNHLFGpPGEFSGLDLAALNIQRGRDHGLPGYNDYREFCGLPPAKSFEDLTDVIPNEVI-AKLRELYGSVDDIDLWV 455
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530388290 584 ALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENP--GVFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVF 657
Cdd:pfam03098 456 GGLAEKPLPGGLVGPTFACIIGDQFRRLRDGDRFWYENGnqGSFTPEQLEEIRKTSLARVICDNTDIIETIQPNVF 531
|
|
| thyroid_peroxidase |
cd09825 |
Thyroid peroxidase (TPO); TPO is a member of the animal heme peroxidase family, which is ... |
128-682 |
0e+00 |
|
Thyroid peroxidase (TPO); TPO is a member of the animal heme peroxidase family, which is expressed in the thyroid and involved in the processing of iodine and iodine compounds. Specifically, TPO oxidizes iodide via hydrogen peroxide to form active iodine, which is then, for example, incorporated into the tyrosine residues of thyroglobulin to yield mono- and di-iodotyrosines.
Pssm-ID: 188657 [Multi-domain] Cd Length: 565 Bit Score: 589.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 128 GAALTAFARLLQPAYRDGIRAPRGLGlpvGSRQ----PLPPPRLVA--TVWARAAAVTPDHSYTRMLMHWGWFLEHDLDH 201
Cdd:cd09825 1 GASNTPLARWLPPIYEDGFSEPVGWN---KERLyngfTLPSVREVSnkIMRTSSTAVTPDDLYSHMLTVWGQYIDHDIDF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 202 TVPALSTARFSDGRPCSSVCTNDPPCFPMNTRHADPRGTHAPCMLFARSSPACASGRPSA---TVDSVYAREQINQQTAY 278
Cdd:cd09825 78 TPQSVSRTMFIGSTDCKMTCENQNPCFPIQLPSEDPRILGRACLPFFRSSAVCGTGDTSTlfgNLSLANPREQINGLTSF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 279 IDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECARQ---EQESPCFLAGDHRANEHLALAAM 355
Cdd:cd09825 158 IDASTVYGSTLALARSLRDLSSDDGLLRVNSKFDDSGRDYLPFQPEEVSSCNPDpngGERVPCFLAGDGRASEVLTLTAS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 356 HTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLRG-YRGYNPNVNAGIINSFA 434
Cdd:cd09825 238 HTLWLREHNRLARALKSINPHWDGEQIYQEARKIVGALHQIITFRDYIPKILGPEAFDQYGGyYEGYDPTVNPTVSNVFS 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 435 TAAFRFGHTLINPILYRLNATLGEISE-GHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFS 513
Cdd:cd09825 318 TAAFRFGHATIHPTVRRLDENFQEHPVlPNLALHDAFFSPWRLVREGGLDPVIRGLIGGPAKLVTPDDLMNEELTEKLFV 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 514 AAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPG 593
Cdd:cd09825 398 LSNSSTLDLASLNLQRGRDHGLPGYNDWREFCGLPRLATPADLATAIADQAVADKILDLYKHPDNIDVWLGGLAEDFLPG 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 594 TRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQLKQASLSRVLCDNGDsIQQVQADVFVKAEYPQDYLNCSEIP 673
Cdd:cd09825 478 ARTGPLFACLIGKQMKALRDGDRFWWENSNVFTDAQRRELRKHSLSRVICDNTG-LTRVPPDAFQLGKFPEDFVSCDSIP 556
|
....*....
gi 530388290 674 KVDLRVWQD 682
Cdd:cd09825 557 GINLEAWRE 565
|
|
| peroxinectin_like |
cd09823 |
peroxinectin_like animal heme peroxidases; Peroxinectin is an arthropod protein that plays a ... |
269-645 |
1.04e-179 |
|
peroxinectin_like animal heme peroxidases; Peroxinectin is an arthropod protein that plays a role in invertebrate immunity mechanisms. Specifically, peroxinectins are secreted as cell-adhesive and opsonic peroxidases. The immunity mechanism appears to involve an interaction between peroxinectin and a transmembrane receptor of the integrin family. Human myeloperoxidase, which is included in this wider family, has also been reported to interact with integrins.
Pssm-ID: 188655 [Multi-domain] Cd Length: 378 Bit Score: 521.75 E-value: 1.04e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 269 REQINQQTAYIDGSNVYGSSERESQALRDPSvpRGLLKTGFPwppSGKPLLPFSTGPPTECARQEQESPCFLAGDHRANE 348
Cdd:cd09823 1 REQLNQVTSFLDGSQVYGSSEEEARKLRTFK--GGLLKTQRR---NGRELLPFSNNPTDDCSLSSAGKPCFLAGDGRVNE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 349 HLALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLR-------GYRGY 421
Cdd:cd09823 76 QPGLTSMHTLFLREHNRIADELKKLNPHWDDERLFQEARKIVIAQMQHITYNEFLPILLGRELMEKFGlylltsgYFNGY 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 422 NPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEIseGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKwrAPSY 501
Cdd:cd09823 156 DPNVDPSILNEFAAAAFRFGHSLVPGTFERLDENYRPQ--GSVNLHDLFFNPDRLYEEGGLDPLLRGLATQPAQ--KVDR 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 502 LLSPELTQRLF-SAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLqNEIKDSEIRQKLRKLYGSPGDID 580
Cdd:cd09823 232 FFTDELTTHFFfRGGNPFGLDLAALNIQRGRDHGLPGYNDYREFCGLPRATTFDDL-LGIMSPETIQKLRRLYKSVDDID 310
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530388290 581 LWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGV---FTPAQLTQLKQASLSRVLCDN 645
Cdd:cd09823 311 LYVGGLSEKPVPGGLVGPTFACIIGEQFRRLRRGDRFWYENGGQpssFTPAQLNEIRKVSLARIICDN 378
|
|
| myeloperoxidase_like |
cd09824 |
Myeloperoxidases, eosinophil peroxidases, and lactoperoxidases; This well conserved family of ... |
250-666 |
1.57e-147 |
|
Myeloperoxidases, eosinophil peroxidases, and lactoperoxidases; This well conserved family of animal heme peroxidases contains members with somewhat diverse functions. Myeloperoxidases are lysosomal proteins found in azurophilic granules of neutrophils and the lysosomes of monocytes. They are involved in the formation of microbicidal agents upon activation of activated neutrophils (neutrophils undergoing respiratory bursts as a result of phagocytosis), by catalyzing the conversion of hydrogen peroxide to hypochlorous acid. As a heme protein, myeloperoxidase is responsible for the greenish tint of pus, which is rich in neutrophils. Eosinophil peroxidases are haloperoxidases as well, preferring bromide over chloride. Expressed by eosinophil granulocytes, they are involved in attacking multicellular parasites and play roles in various inflammatory diseases such as asthma. The haloperoxidase lactoperoxidase is secreted from mucosal glands and provides antibacterial activity by oxidizing a variety of substrates such as bromide or chloride in the presence of hydrogen peroxide.
Pssm-ID: 188656 [Multi-domain] Cd Length: 411 Bit Score: 440.32 E-value: 1.57e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 250 SSPACASGRPsatvdsvyAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTEC 329
Cdd:cd09824 1 SCGACTSKRN--------VREQINALTSFVDASMVYGSEPSLAK*LRNLTNQLGLLAVNQRFTDNGLALLPFENLHNDPC 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 330 A--RQEQESPCFLAGDHRANEHLALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVL 407
Cdd:cd09824 73 AlrNTSANIPCFLAGDTRVSENPGLAALHTLLLREHNRLARELHRLNPHWDGETLYQEARKIVGAMVQIITYRDYLPLIL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 408 GDPGTRMLRGYRGYNPNVNAGIINSFATAaFRFGHTLINPILYRLNATLGEI-SEGHLPFHKALFSPSRIIKEGGIDPVL 486
Cdd:cd09824 153 GEDAAARLPPYRGYNESVDPRIANVFTTA-FRRGHTTVQPFVFRLDENYQPHpPNPQVPLHKAFFASWRIIREGGIDPIL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 487 RGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIR 566
Cdd:cd09824 232 RGLMATPAKLNNQNQMLVDELRERLFQQTKRMGLDLAALNLQRGRDHGLPGYNAWRRFCGLSQPQNLAELAAVLNNTVLA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 567 QKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQLKQASLSRVLCDNg 646
Cdd:cd09824 312 RKLLDLYGTPDNIDIWIGGVAEPLVPGGRVGPLLACLISRQFRRIRDGDRFWWENPGVFTEEQRESLRSVSLSRIICDN- 390
|
410 420
....*....|....*....|
gi 530388290 647 DSIQQVQADVFVKAEYPQDY 666
Cdd:cd09824 391 TGITKVPRDPFQPNSYPRDF 410
|
|
| peroxinectin_like_bacterial |
cd09822 |
Uncharacterized family of heme peroxidases, mostly bacterial; Animal heme peroxidases are ... |
162-658 |
8.33e-118 |
|
Uncharacterized family of heme peroxidases, mostly bacterial; Animal heme peroxidases are diverse family of enzymes which are not restricted to animals. Members are also found in metazoans, fungi, and plants, and also in bacteria - like most members of this family of uncharacterized proteins.
Pssm-ID: 188654 [Multi-domain] Cd Length: 420 Bit Score: 363.94 E-value: 8.33e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 162 LPPPRLVATVWARAAAVTPDHSY-TRMLMHWGWFLEHDLDHTvpalstarfsDGRPcssvctndppcfpmntrhadprgt 240
Cdd:cd09822 2 RPSPREISNAVADQTESIPNSRGlSDWFWVWGQFLDHDIDLT----------PDNP------------------------ 47
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 241 hapcmlfarsspacasgrpsatvdsvyaREQINQQTAYIDGSNVYGSSERESQALRdpSVPRGLLKTGfpwPPSGKPLLP 320
Cdd:cd09822 48 ----------------------------REQINAITAYIDGSNVYGSDEERADALR--SFGGGKLKTS---VANAGDLLP 94
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 321 FSTGPPTECARQEQESPCFLAGDHRANEHLALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYS 400
Cdd:cd09822 95 FNEAGLPNDNGGVPADDLFLAGDVRANENPGLTALHTLFVREHNRLADELARRNPSLSDEEIYQAARAIVIAEIQAITYN 174
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 401 HWLPKVLGDpgtRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNatLGEISEGHLPFHKALFSPSRiIKEG 480
Cdd:cd09822 175 EFLPALLGE---NALPAYSGYDETVNPGISNEFSTAAYRFGHSMLSSELLRGD--EDGTEATSLALRDAFFNPDE-LEEN 248
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 481 GIDPVLRGLfgvaAKWRAP---SYLLSpELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQ 557
Cdd:cd09822 249 GIDPLLRGL----ASQVAQeidTFIVD-DVRNFLFGPPGAGGFDLAALNIQRGRDHGLPSYNQLREALGLPAVTSFSDIT 323
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 558 neiKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPgVFTPAQLTQLKQAS 637
Cdd:cd09822 324 ---SDPDLAARLASVYGDVDQIDLWVGGLAEDHVNGGLVGETFSTIIADQFTRLRDGDRFFYEND-DLLLDEIADIENTT 399
|
490 500
....*....|....*....|.
gi 530388290 638 LSRVLCDNGDsIQQVQADVFV 658
Cdd:cd09822 400 LADVIRRNTD-VDDIQDNVFL 419
|
|
| An_peroxidase_like |
cd05396 |
Animal heme peroxidases and related proteins; A diverse family of enzymes, which includes ... |
271-645 |
5.00e-105 |
|
Animal heme peroxidases and related proteins; A diverse family of enzymes, which includes prostaglandin G/H synthase, thyroid peroxidase, myeloperoxidase, linoleate diol synthase, lactoperoxidase, peroxinectin, peroxidasin, and others. Despite its name, this family is not restricted to metazoans: members are found in fungi, plants, and bacteria as well.
Pssm-ID: 188647 [Multi-domain] Cd Length: 370 Bit Score: 328.62 E-value: 5.00e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 271 QINQQTAYIDGSNVYGSSERESQALRdpSVPRGLLKTGFPWPPS-GKPLLPFSTGPPTECARQEQESPCFLAGDHRANEH 349
Cdd:cd05396 1 QLNARTPYLDGSSIYGSNPDVARALR--TFKGGLLKTNEVKGPSyGTELLPFNNPNPSMGTIGLPPTRCFIAGDPRVNEN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 350 LALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLG-DPGTRMLRGYRGYNPNVNAG 428
Cdd:cd05396 79 LLLLAVHTLFLREHNRLADRLKKEHPEWDDERLYQEARLIVIAQYQLITYNEYLPAILGkFTDPRDDLVLLFPDPDVVPY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 429 IINSFATAAFRFGHTLINPILYRLNATLGEISEGHLPFHKALFSPSR-IIKEGGIDPVLRGLFGVAAK----WRAPSYLL 503
Cdd:cd05396 159 VLSEFFTAAYRFGHSLVPEGVDRIDENGQPKEIPDVPLKDFFFNTSRsILSDTGLDPLLRGFLRQPAGlidqNVDDVMFL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 504 SPELTQRLFsaaysaavDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLqneIKDSEIRQKLRKLYGSPGDIDLWP 583
Cdd:cd05396 239 FGPLEGVGL--------DLAALNIQRGRDLGLPSYNEVRRFIGLKPPTSFQDI---LTDPELAKKLAELYGDPDDVDLWV 307
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530388290 584 ALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQL-KQASLSRVLCDN 645
Cdd:cd05396 308 GGLLEKKVPPARLGELLATIILEQFKRLVDGDRFYYVNYNPFGKSGKEELeKLISLADIICLN 370
|
|
| dual_peroxidase_like |
cd09820 |
Dual oxidase and related animal heme peroxidases; Animal heme peroxidases of the dual-oxidase ... |
116-666 |
5.51e-83 |
|
Dual oxidase and related animal heme peroxidases; Animal heme peroxidases of the dual-oxidase like subfamily play vital roles in the innate mucosal immunity of gut epithelia. They provide reactive oxygen species which help control infection.
Pssm-ID: 188652 [Multi-domain] Cd Length: 558 Bit Score: 276.49 E-value: 5.51e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 116 DGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPvgsrqplpPPRLVATVWARAAAVTPDHSYTRMLMhwGWFL 195
Cdd:cd09820 2 DGWYNNLAHPEWGAADSRLTRRLPAHYSDGVYAPSGEERP--------NPRSLSNLLMKGESGLPSTRNRTALL--VFFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 196 EHDLDHTVPAlstarfsdGRP-CssvctndPPCF-----PMNTRHADPRGTHAPCMLFARSSPACASGR-PSAtvdsvyA 268
Cdd:cd09820 72 QHVVSEILDA--------SRPgC-------PPEYfnieiPKGDPVFDPECTGNIELPFQRSRYDKNTGYsPNN------P 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 269 REQINQQTAYIDGSNVYGSSERESQALRdpSVPRGLLKTGFPW--PPSGKPLLPFSTGPPTECARQEQESPCFLAGDHRA 346
Cdd:cd09820 131 REQLNEVTSWIDGSSIYGSSKAWSDALR--SFSGGRLASGDDGgfPRRNTNRLPLANPPPPSYHGTRGPERLFKLGNPRG 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 347 NEHLALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPgtrmLRGYRGYNPNVN 426
Cdd:cd09820 209 NENPFLLTFGILWFRYHNYLAQRIAREHPDWSDEDIFQEARKWVIATYQNIVFYEWLPALLGTN----VPPYTGYKPHVD 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 427 AGIINSFATAAFRFGHTLINPILYRLNAT--LGEISEGHLPFHkAL------FSPSRIIKEGGIDPVLRGLFG-VAAKwr 497
Cdd:cd09820 285 PGISHEFQAAAFRFGHTLVPPGVYRRNRQcnFREVLTTSGGSP-ALrlcntyWNSQEPLLKSDIDELLLGMASqIAER-- 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 498 aPSYLLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEI--KDSEIRQKLRKLYG- 574
Cdd:cd09820 362 -EDNIIVEDLRDYLFGPLEFSRRDLMALNIQRGRDHGLPDYNTAREAFGLPPRTTWSDINPDLfkKDPELLERLAELYGn 440
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 575 SPGDIDLWPALMVEDLipGTRVGPtlmcLFVT----QFQRLRDGDRFWYENP--GVFTPAQLTQLKQASLSRVLC----- 643
Cdd:cd09820 441 DLSKLDLYVGGMLESK--GGGPGE----LFRAiildQFQRLRDGDRFWFENVknGLFTAEEIEEIRNTTLRDVILavtdi 514
|
570 580
....*....|....*....|....*.
gi 530388290 644 DNGDSiqqvQADVFVKAEY---PQDY 666
Cdd:cd09820 515 DNTDL----QKNVFFWKNGdpcPQPK 536
|
|
| prostaglandin_endoperoxide_synthase |
cd09816 |
Animal prostaglandin endoperoxide synthase and related bacterial proteins; Animal ... |
279-645 |
4.97e-33 |
|
Animal prostaglandin endoperoxide synthase and related bacterial proteins; Animal prostaglandin endoperoxide synthases, including prostaglandin H2 synthase and a set of similar bacterial proteins which may function as cyclooxygenases. Prostaglandin H2 synthase catalyzes the synthesis of prostaglandin H2 from arachidonic acid. In two reaction steps, arachidonic acid is converted to Prostaglandin G2, a peroxide (cyclooxygenase activity) and subsequently converted to the end product via the enzyme's peroxidase activity. Prostaglandin H2 synthase is the target of aspirin and other non-steroid anti-inflammatory drugs such as ibuprofen, which block the substrate's access to the active site and may acetylate a conserved serine residue. In humans and other mammals, prostaglandin H2 synthase (PGHS), also called cyclooxygenase (COX) is present as at least two isozymes, PGHS-1 (or COX-1) and PGHS-2 (or COX-2), respectively. PGHS-1 is expressed constitutively in most mammalian cells, while the expression of PGHS-2 is induced via inflammation response in endothelial cells, activated macrophages, and others. COX-3 is a splice variant of COX-1.
Pssm-ID: 188648 [Multi-domain] Cd Length: 490 Bit Score: 133.93 E-value: 4.97e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 279 IDGSNVYGSSERESQALRdpSVPRGLLKT----GFPWPP----SGKPLLPFSTGPPT--ECARQEQESPCFLAGDHRANE 348
Cdd:cd09816 131 IDLSQIYGLTEARTHALR--LFKDGKLKSqminGEEYPPylfeDGGVKMEFPPLVPPlgDELTPEREAKLFAVGHERFNL 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 349 HLALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAEL---------QHITYSHwlPKVLGDPGtrMLRGYR 419
Cdd:cd09816 209 TPGLFMLNTIWLREHNRVCDILKKEHPDWDDERLFQTARNILIGELikiviedyiNHLSPYH--FKLFFDPE--LAFNEP 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 420 GYNPNvnagiinsfaTAAFRFGHtlinpiLYRLNATLGE---ISEGHLPFHKALFSPSRIIKEGgidpvLRGLFGVAAKW 496
Cdd:cd09816 285 WQRQN----------RIALEFNL------LYRWHPLVPDtfnIGGQRYPLSDFLFNNDLVVDHG-----LGALVDAASRQ 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 497 RApsyllsPELTQRLFsAAYSAAVDSAAtiIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNeikDSEIRQKLRKLYGSP 576
Cdd:cd09816 344 PA------GRIGLRNT-PPFLLPVEVRS--IEQGRKLRLASFNDYRKRFGLPPYTSFEELTG---DPEVAAELEELYGDV 411
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530388290 577 GDIDLWPALMVEDLIPGTRVGPTlMCLFVTQF---QRLRD--GDRFWYeNPGVFTPAQLTQLKQ-ASLSRVLCDN 645
Cdd:cd09816 412 DAVEFYVGLFAEDPRPNSPLPPL-MVEMVAPDafsGALTNplLSPEVW-KPSTFGGEGGFDIVKtATLQDLVCRN 484
|
|
| An_peroxidase_bacterial_2 |
cd09821 |
Uncharacterized bacterial family of heme peroxidases; Animal heme peroxidases are diverse ... |
257-663 |
6.53e-31 |
|
Uncharacterized bacterial family of heme peroxidases; Animal heme peroxidases are diverse family of enzymes which are not restricted to metazoans; members are also found in fungi, and plants, and in bacteria - like this family of uncharacterized proteins.
Pssm-ID: 188653 [Multi-domain] Cd Length: 570 Bit Score: 128.69 E-value: 6.53e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 257 GRPSATVDSVYAREQINQQTAYIDGSNVYGSSERESQALR----DP--------SVPRGLLKTGFP--------WPPSGK 316
Cdd:cd09821 69 GPDGILGTADGEGEHTNVTTPFVDQNQTYGSHASHQVFLReydgDGvatgrlleGATGGSARTGHAflddiahnAAPKGG 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 317 P--LLPFSTGPPTECARQ-----EQESPCFLAGDHRANEHLALAAMHTLWFREHNRMATELSAL---------------- 373
Cdd:cd09821 149 LgsLRDNPTEDPPGPGAPgsydnELLDAHFVAGDGRVNENIGLTAVHTVFHREHNRLVDQIKDTllqsadlafaneaggn 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 374 NPHWEGNTVYQEARKIVGAELQHITYSHWLPKVlgDPGTRMLRGYRGYNPNVNAGIINSFATAAFRFGHTLI--NPILYR 451
Cdd:cd09821 229 NLAWDGERLFQAARFANEMQYQHLVFEEFARRI--QPGIDGFGSFNGYNPEINPSISAEFAHAVYRFGHSMLteTVTRIG 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 452 LNATLGEISEGHL---PFHKALFSPSRIIKEGGIDPVLRGLFgvaakwRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQ 528
Cdd:cd09821 307 PDADEGLDNQVGLidaFLNPVAFLPATLYAEEGAGAILRGMT------RQVGNEIDEFVTDALRNNLVGLPLDLAALNIA 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 529 RGRDHGIP--------------------PY---VDFRvfcnlTSVKNFEDLQNEIK----------DSEIRQK----LRK 571
Cdd:cd09821 381 RGRDTGLPtlnearaqlfaatgdtilkaPYeswNDFG-----ARLKNPESLINFIAaygthltitgATTLAAKraaaQDL 455
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 572 LYGSPGD-----------------------IDLWPALMVEDLIP-GTRVGPTLMCLFVTQFQRLRDGDRFWY--ENPGVF 625
Cdd:cd09821 456 VDGGDGApadradfmnaagagagtvkgldnVDLWVGGLAEKQVPfGGMLGSTFNFVFEEQMDRLQDGDRFYYlsRTAGLD 535
|
490 500 510
....*....|....*....|....*....|....*...
gi 530388290 626 TpaqLTQLKQASLSRVLCDNGDSiQQVQADVFVKAEYP 663
Cdd:cd09821 536 L---LNQLENNTFADMIMRNTGA-THLPQDIFSVPDYD 569
|
|
| PIOX_like |
cd09818 |
Animal heme oxidases similar to plant pathogen-inducible oxygenases; This is a diverse family ... |
113-643 |
7.63e-28 |
|
Animal heme oxidases similar to plant pathogen-inducible oxygenases; This is a diverse family of oxygenases related to the animal heme peroxidases, with members from plants, animals, and bacteria. The plant pathogen-inducible oxygenases (PIOX) oxygenate fatty acids into 2R-hydroperoxides. They may be involved in the hypersensitive reaction, rapid and localized cell death induced by infection with pathogens, and the rapidly induced expression of PIOX may be caused by the oxidative burst that occurs in the process of cell death.
Pssm-ID: 188650 [Multi-domain] Cd Length: 484 Bit Score: 118.16 E-value: 7.63e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 113 RAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLglpvgsrqpLPPPRLVATVWARAAAVTPDHSYTRMLMHWG 192
Cdd:cd09818 1 RTADGSYNDLDNPSMGSVGTRFGRNVPLDATFPEDKDELL---------TPNPRVISRRLLARTEFKPATSLNLLAAAWI 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 193 WFLEHD-LDHTVPALstarfsdgrpcssvctndppcfpmntrhadprgthapcmlfarsspacasgrpsatvdsvyareq 271
Cdd:cd09818 72 QFMVHDwFSHGPPTY----------------------------------------------------------------- 86
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 272 INQQTAYIDGSNVYGSSERESQALRDPsvprgllktgfpwPPSGKPLLPFSTGPPTEcarqeQESPCFLAGDHRaNEHLA 351
Cdd:cd09818 87 INTNTHWWDGSQIYGSTEEAQKRLRTF-------------PPDGKLKLDADGLLPVD-----EHTGLPLTGFND-NWWVG 147
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 352 LAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRM--------LRGYRGYN- 422
Cdd:cd09818 148 LSLLHTLFVREHNAICDALRKEYPDWSDEQLFDKARLVNAALMAKIHTVEWTPAILAHPTLEIamranwwgLLGERLKRv 227
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 423 ------PNVNAGIINSFA-------------TAAFRFgHTLInPILYRL-----NATLGEISEGHLPFHKAlfspSRIIK 478
Cdd:cd09818 228 lgrdgtSELLSGIPGSPPnhhgvpyslteefVAVYRM-HPLI-PDDIDFrsaddGATGEEISLTDLAGGKA----RELLR 301
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 479 EGGIDPVLRGlFGVAAK-----WRAPSYLlspeltqRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNF 553
Cdd:cd09818 302 KLGFADLLYS-FGITHPgaltlHNYPRFL-------RDLHRPDGRVIDLAAIDILRDRERGVPRYNEFRRLLHLPPAKSF 373
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 554 EDLQNeikDSEIRQKLRKLYGspGDI---DLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFW--YENPGVFTPA 628
Cdd:cd09818 374 EDLTG---DEEVAAELREVYG--GDVekvDLLVGLLAEPLPPGFGFSDTAFRIFILMASRRLKSDRFFtnDFRPEVYTPE 448
|
570
....*....|....*
gi 530388290 629 QLTQLKQASLSRVLC 643
Cdd:cd09818 449 GMDWVNNNTMKSVLL 463
|
|
| An_peroxidase_bacterial_1 |
cd09819 |
Uncharacterized bacterial family of heme peroxidases; Animal heme peroxidases are diverse ... |
273-496 |
1.84e-13 |
|
Uncharacterized bacterial family of heme peroxidases; Animal heme peroxidases are diverse family of enzymes which are not restricted to metazoans; members are also found in fungi, and plants, and in bacteria - like this family of uncharacterized proteins.
Pssm-ID: 188651 Cd Length: 465 Bit Score: 73.53 E-value: 1.84e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 273 NQQTAYIDGSNVYGSSERESQALRDPSVP--RGLLKTGFPWPPSGKPLLPfstGPPTECARQEQESPcfLAGDHRANEHL 350
Cdd:cd09819 81 NFRTPALDLDSVYGGGPDGSPYLYDQATPndGAKLRVGRESPGGPGGLPG---DGARDLPRNGQGTA--LIGDPRNDENL 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 351 ALAAMHTLWFREHNRMATELSALNPhwEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTR--MLRGYRGY-NPNVNA 427
Cdd:cd09819 156 IVAQLHLAFLRFHNAVVDALRAHGT--PGDELFEEARRLVRWHYQWLVLNDFLPRICDPDVVDdvLANGRRFYrFFREGK 233
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 428 GIIN-SFATAAFRFGHTLINPIlYRLNATLGEISeghlpfHKALFSPSriikeGGIDPVLRGLFGVAAKW 496
Cdd:cd09819 234 PFMPvEFSVAAYRFGHSMVRAS-YDYNRNFPDAS------LELLFTFT-----GGGEGDLGGFSPLPENW 291
|
|
| linoleate_diol_synthase_like |
cd09817 |
Linoleate (8R)-dioxygenase and related enzymes; These fungal enzymes, related to animal heme ... |
111-640 |
3.71e-12 |
|
Linoleate (8R)-dioxygenase and related enzymes; These fungal enzymes, related to animal heme peroxidases, catalyze the oxygenation of linoleate and similar targets. Linoleate (8R)-dioxygenase, also called linoleate:oxygen 7S,8S-oxidoreductase, generates (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate as a product. Other members are 5,8-linoleate dioxygenase (LDS, ppoA) and linoleate 10R-dioxygenase (ppoC), involved in the biosynthesis of oxylipins.
Pssm-ID: 188649 [Multi-domain] Cd Length: 550 Bit Score: 69.67 E-value: 3.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 111 KYRAHDGTCNNLQQPTWGAALTAFARLLQPAyrdgiraprGLGLPVgsrqpLPPPRLV-ATVWARAAAVTPDHSYTRMLM 189
Cdd:cd09817 32 KYRKADGSNNNILNPRLGAAGSPYARSVPPK---------HDQPGV-----LPDPGLIfDTLLARDTGKFHPNGISSMLF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 190 HWGWFLEHDLdhtvpalstarfsdgrpcssvctndppcfpMNTRHADPrgthapcmlfarsspacasgrpsatvdsvyar 269
Cdd:cd09817 98 YLATIIIHDI------------------------------FRTDHRDM-------------------------------- 115
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 270 eQINQQTAYIDGSNVYGSSERESQALRDpsvprglLKTGFPWP--PSGKPLLPFstgPPTECArqeqespcflagdhran 347
Cdd:cd09817 116 -NINNTSSYLDLSPLYGSNQEEQNKVRT-------MKDGKLKPdtFSDKRLLGQ---PPGVCA----------------- 167
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 348 ehlalaaMHTLWFREHNRMATELSALN-----------------PHWEGNTVYQEARKIVGAELQHITYSHWLPKVLG-- 408
Cdd:cd09817 168 -------LLVMFNRFHNYVVEQLAQINeggrftppgdkldssakEEKLDEDLFQTARLITCGLYINIVLHDYVRAILNln 240
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 409 --------DPGTRMLRGYRGynpnVNAGIINsFATAAFRFghtlinpiLYRLNATLGEISEGHLPFHKALFSPSRIIKEG 480
Cdd:cd09817 241 rtdstwtlDPRVEIGRSLTG----VPRGTGN-QVSVEFNL--------LYRWHSAISARDEKWTEDLFESLFGGKSPDEV 307
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 481 GIDPVLRGLfgvaAKWRApsyLLSPELTQRLFSA---------------------------AYSA----AVDSAATI--I 527
Cdd:cd09817 308 TLKEFMQAL----GRFEA---LIPKDPSQRTFGGlkrgpdgrfrdedlvrilkdsiedpagAFGArnvpASLKVIEIlgI 380
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 528 QRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNeikDSEIRQKLRKLYGSPGDIDLWPALMVED----LIPGTRVGPTlmcl 603
Cdd:cd09817 381 LQAREWNVATLNEFRKFFGLKPYETFEDINS---DPEVAEALELLYGHPDNVELYPGLVAEDakppMPPGSGLCPG---- 453
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 530388290 604 FVTQFQRLRD------GDRFW-YEnpgvFTPAQLTQLKQASLSR 640
Cdd:cd09817 454 YTISRAILSDavalvrGDRFYtVD----YNPNNLTNWGYAEVSP 493
|
|
| PLN02283 |
PLN02283 |
alpha-dioxygenase |
272-621 |
1.27e-10 |
|
alpha-dioxygenase
Pssm-ID: 177921 [Multi-domain] Cd Length: 633 Bit Score: 65.17 E-value: 1.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 272 INQQTAYIDGSNVYGSSERESQALRdpSVPRGLLKTgfpwppSGKPLLpfstgpptecARQEQESPcfLAGDHRaNEHLA 351
Cdd:PLN02283 207 LNIRTPWWDGSVIYGSNEKGLRRVR--TFKDGKLKI------SEDGLL----------LHDEDGIP--ISGDVR-NSWAG 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 352 LAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVL------------------------ 407
Cdd:PLN02283 266 VSLLQALFVKEHNAVCDALKEEYPDFDDEELYRHARLVTSAVIAKIHTIDWTVELLktdtllagmranwygllgkkfkdt 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 408 -GDPGTRMLRGYRGYNPNVNAGIINSFA---TAAFRFgHTLI-----------NPILYRLNATLGEISEGHLPFHKALFS 472
Cdd:PLN02283 346 fGHIGGPILSGLVGLKKPNNHGVPYSLTeefTSVYRM-HSLLpdhlilrditaAPGENKSPPLIEEIPMPELIGLKGEKK 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530388290 473 PSRIIKEGGIDPVLRGLFGVAAKWRAPSYL--LSPeltQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSV 550
Cdd:PLN02283 425 LSKIGFEKLMVSMGHQACGALELWNYPSWMrdLVP---QDIDGEDRPDHVDMAALEIYRDRERGVARYNEFRRNLLMIPI 501
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530388290 551 KNFEDLQNeikDSEIRQKLRKLYGspGDI---DLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYEN 621
Cdd:PLN02283 502 SKWEDLTD---DEEAIEVLREVYG--DDVeklDLLVGLMAEKKIKGFAISETAFFIFLLMASRRLEADRFFTSN 570
|
|
| VWC |
smart00214 |
von Willebrand factor (vWF) type C domain; |
785-835 |
5.11e-10 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214564 Cd Length: 59 Bit Score: 55.99 E-value: 5.11e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 530388290 785 GVPRKAEERWMKEDCTHCICESGQ-VTCVVEICPPAP-CPSPELVK--GTCCPVC 835
Cdd:smart00214 5 GRVYNDGETWKPDPCQICTCLDGTtVLCDPVECPPPPdCPNPERVKppGECCPRC 59
|
|
| VWC |
pfam00093 |
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ... |
784-835 |
8.43e-10 |
|
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.
Pssm-ID: 278520 Cd Length: 57 Bit Score: 55.12 E-value: 8.43e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 530388290 784 RGVPRKAEERWMKEDCTHCICESGQVTCVVEICPPAPCPSPELVK--GTCCPVC 835
Cdd:pfam00093 4 NGVVYENGETWKPDLCTICTCDDGKVLCDKIICPPLDCPNPRLEIppGECCPVC 57
|
|
| TILa |
pfam12714 |
TILa domain; This cysteine rich domain occurs along side the TIL pfam01826 domain and is ... |
780-818 |
6.97e-05 |
|
TILa domain; This cysteine rich domain occurs along side the TIL pfam01826 domain and is likely to be a distantly related relative.
Pssm-ID: 432736 Cd Length: 54 Bit Score: 41.14 E-value: 6.97e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 530388290 780 CTDVRGVPRKAEERWMKEDCT-HCICESGQVTCVVEICPP 818
Cdd:pfam12714 1 CKDAQGNYIPAGKTWFSSGCTqSCTCTGGNIQCQPFQCPP 40
|
|
| Amnionless |
pfam14828 |
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for ... |
798-835 |
2.48e-03 |
|
Amnionless; The amnionless protein forms a complex with cubilin. This complex is necessary for vitamin B12 uptake.
Pssm-ID: 464340 Cd Length: 449 Bit Score: 41.22 E-value: 2.48e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 530388290 798 DCTHCIC---ESGQVTC--VVEICPPAPCPSPELVKGTCCPVC 835
Cdd:pfam14828 193 DPSGCGCgndENLERICanVLQRCPPPHCLSPLRPEGHCCDVC 235
|
|
| VWC_out |
smart00215 |
von Willebrand factor (vWF) type C domain; |
784-821 |
2.93e-03 |
|
von Willebrand factor (vWF) type C domain;
Pssm-ID: 214565 Cd Length: 67 Bit Score: 37.16 E-value: 2.93e-03
10 20 30
....*....|....*....|....*....|....*...
gi 530388290 784 RGVPRKAEERWmKEDCTHCICESGQVTCVVEICPPAPC 821
Cdd:smart00215 4 NGSYYPPGAKW-DDDCNRCTCLNGRVSCTKVWCGPKPC 40
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