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Conserved domains on  [gi|530374448|ref|XP_005247430|]
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golgin subfamily B member 1 isoform X7 [Homo sapiens]

Protein Classification

coiled-coil domain-containing protein( domain architecture ID 1000095)

coiled-coil domain-containing protein contains a region with alpha-helical coiled-coil sequence signatures that is being annotated by a variety of protein family models, not necessarily indicating family membership

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1865-2737 2.31e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.31e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1865 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1934
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1935 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2007
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2008 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2084
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2085 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2162
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2163 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2240
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2241 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2317
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2318 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2389
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2390 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2469
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2470 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2549
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2550 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2629
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2630 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2705
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 530374448  2706 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2737
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1317-2144 2.52e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.52e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1317 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1396
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1397 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1473
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1474 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1553
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1554 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1633
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1634 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1713
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1714 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1793
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1794 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1867
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1868 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1947
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1948 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2026
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2027 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2106
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 530374448  2107 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2144
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 723-1497 6.71e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.71e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   723 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 802
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   803 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 882
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   883 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 962
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   963 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1041
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1042 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1107
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1108 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1163
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1164 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1214
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1215 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1289
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1290 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1359
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1360 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1427
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530374448  1428 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1497
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 191-983 7.44e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 7.44e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   191 QLQEKEEFISTLQAQL--SQTQAEQAAQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHN 268
Cdd:TIGR02168  233 RLEELREELEELQEELkeAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   269 TLRNT---VETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHkaemeektshi 345
Cdd:TIGR02168  313 NLERQleeLEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----------- 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   346 lslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSfpdvynEG 425
Cdd:TIGR02168  382 -------ETLRSKVAQLELQIASL----NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL------EE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   426 TQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEA-QNRTGEADREVSEI------------- 491
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlQENLEGFSEGVKALlknqsglsgilgv 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   492 --SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLlemKEAQEEIAFLKLQLQGKRAEEADHEVLdQKEMKQM 565
Cdd:TIGR02168  525 lsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK---QNELGRVTFLPLDSIKGTEIQGNDREI-LKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   566 EGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKS-----TKQDGDKSLSAvp 640
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRpggviTGGSAKTNSSI-- 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   641 digQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL 720
Cdd:TIGR02168  673 ---LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   721 SmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSL 800
Cdd:TIGR02168  746 E------ERIAQLSKELTELEAEI-----------EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   801 QSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISF---SMTEK 877
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNeraSLEEA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   878 MVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMspAGQISkEELQHEFDLLKKENEQRKR 957
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLS-EEYSLTLEEAEALENKIED 965

                          810       820
                   ....*....|....*....|....*.
gi 530374448   958 KLQaalinrkELLQRVSRLEEELANL 983
Cdd:TIGR02168  966 DEE-------EARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2418-3151 2.14e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.14e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2418 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2487
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2488 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2561
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2562 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2624
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2625 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2688
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2689 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2760
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2761 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2840
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2841 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2920
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2921 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3000
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  3001 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3080
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530374448  3081 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3151
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
PRK10929 super family cl35973
putative mechanosensitive channel protein; Provisional
 57-290 3.09e-04

putative mechanosensitive channel protein; Provisional


The actual alignment was detected with superfamily member PRK10929:

Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.59  E-value: 3.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   57 AEQLVVELKDIIRQKDVQLQQKDEALQ------EERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEP-QSE 129
Cdd:PRK10929   25 EKQITQELEQAKAAKTPAQAEIVEALQsalnwlEERKGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVPPnMST 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  130 EQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEqpaqsstemeefvmMKQQLQEKEEFISTL------- 202
Cdd:PRK10929  105 DALEQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTE--------------ARRQLNEIERRLQTLgtpntpl 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  203 -QAQLSQTQAEQAAQKLRVLQRKLeeheeslvgrAQVVDLLQQELtaAEQRNQILSQQLQQMEAEHNTLRNTVETER-EE 280
Cdd:PRK10929  171 aQAQLTALQAESAALKALVDELEL----------AQLSANNRQEL--ARLRSELAKKRSQQLDAYLQALRNQLNSQRqRE 238

                         250
                  ....*....|
gi 530374448  281 SKILLEKMEL 290
Cdd:PRK10929  239 AERALESTEL 248
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1865-2737 2.31e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.31e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1865 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1934
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1935 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2007
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2008 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2084
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2085 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2162
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2163 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2240
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2241 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2317
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2318 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2389
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2390 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2469
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2470 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2549
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2550 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2629
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2630 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2705
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 530374448  2706 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2737
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1317-2144 2.52e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.52e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1317 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1396
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1397 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1473
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1474 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1553
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1554 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1633
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1634 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1713
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1714 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1793
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1794 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1867
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1868 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1947
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1948 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2026
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2027 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2106
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 530374448  2107 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2144
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 723-1497 6.71e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.71e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   723 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 802
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   803 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 882
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   883 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 962
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   963 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1041
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1042 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1107
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1108 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1163
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1164 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1214
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1215 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1289
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1290 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1359
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1360 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1427
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530374448  1428 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1497
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 191-983 7.44e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 7.44e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   191 QLQEKEEFISTLQAQL--SQTQAEQAAQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHN 268
Cdd:TIGR02168  233 RLEELREELEELQEELkeAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   269 TLRNT---VETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHkaemeektshi 345
Cdd:TIGR02168  313 NLERQleeLEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----------- 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   346 lslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSfpdvynEG 425
Cdd:TIGR02168  382 -------ETLRSKVAQLELQIASL----NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL------EE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   426 TQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEA-QNRTGEADREVSEI------------- 491
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlQENLEGFSEGVKALlknqsglsgilgv 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   492 --SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLlemKEAQEEIAFLKLQLQGKRAEEADHEVLdQKEMKQM 565
Cdd:TIGR02168  525 lsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK---QNELGRVTFLPLDSIKGTEIQGNDREI-LKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   566 EGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKS-----TKQDGDKSLSAvp 640
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRpggviTGGSAKTNSSI-- 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   641 digQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL 720
Cdd:TIGR02168  673 ---LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   721 SmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSL 800
Cdd:TIGR02168  746 E------ERIAQLSKELTELEAEI-----------EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   801 QSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISF---SMTEK 877
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNeraSLEEA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   878 MVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMspAGQISkEELQHEFDLLKKENEQRKR 957
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLS-EEYSLTLEEAEALENKIED 965

                          810       820
                   ....*....|....*....|....*.
gi 530374448   958 KLQaalinrkELLQRVSRLEEELANL 983
Cdd:TIGR02168  966 DEE-------EARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1798-2343 1.29e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1798 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVtkmNLLNQQIQEELSRVTKLKE 1877
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIARLEE 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1878 TAEEEKDDLEeRLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1957
Cdd:COG1196   310 RRRELEERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1958 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKA 2037
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2038 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALR 2113
Cdd:COG1196   469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAAL 548

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2114 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2193
Cdd:COG1196   549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2194 EDNC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHS 2266
Cdd:COG1196   629 AARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530374448 2267 SQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLhEEINM 2343
Cdd:COG1196   709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL-GPVNL 784
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1334-1901 2.18e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 2.18e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1334 LQQKLESSQLQIAGLeHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1413
Cdd:COG1196   218 LKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1414 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1493
Cdd:COG1196   297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1494 QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEstewQEKHK 1573
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1574 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETE------KQLQEAEQEMEEMKEKMRKFAK 1647
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGV 532

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1648 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLM----------SEKDSLS 1717
Cdd:COG1196   533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGaigaavdlvaSDLREAD 612

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1718 EEVQDLKHQIEGNVSKQANLEATEKHDNQTN-----VTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKD 1792
Cdd:COG1196   613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAgrlreVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1793 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV 1872
Cdd:COG1196   693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 530374448 1873 TKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1901
Cdd:COG1196   773 EREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2418-3151 2.14e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.14e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2418 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2487
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2488 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2561
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2562 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2624
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2625 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2688
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2689 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2760
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2761 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2840
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2841 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2920
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2921 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3000
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  3001 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3080
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530374448  3081 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3151
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 723-1084 3.35e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 3.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  723 VTELRAQVKQLEmnlAEAERQRRldYesqtahdnllteqihsLSIEAKSKDVKIEVLQNELDDVQLQfseqstlIRSLQS 802
Cdd:COG1196   195 LGELERQLEPLE---RQAEKAER--Y----------------RELKEELKELEAELLLLKLRELEAE-------LEELEA 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  803 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 882
Cdd:COG1196   247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  883 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRkLQAA 962
Cdd:COG1196   327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ-LEEL 405

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  963 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEysekcvtskcqeieiylkqtisEKEVELQHIRK 1042
Cdd:COG1196   406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA----------------------ELEEEEEALLE 463

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 530374448 1043 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1084
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1459-2052 1.48e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.40  E-value: 1.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1459 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD---RSLLENQSLSSSCES 1535
Cdd:PRK03918  163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1536 LKLALEGLTEDKEKL---VKEIESLKSSKIAESTEWQEKHKELQ------KEYEILLQSYENVSNEAERIQHVVEAVRQE 1606
Cdd:PRK03918  243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1607 KQELYGKLRstEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPagdtakecmetllssna 1686
Cdd:PRK03918  323 INGIEERIK--ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG----------------- 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1687 smkEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvSKQANLEATEKHDNQTNV-----TEEGTQSIPGET 1761
Cdd:PRK03918  384 ---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK---ELKKAIEELKKAKGKCPVcgrelTEEHRKELLEEY 457

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1762 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKEriagLEEE-KQKNKEFSQTLENEKNTLLSQ 1840
Cdd:PRK03918  458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE----LEEKlKKYNLEELEKKAEEYEKLKEK 533

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1841 ISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLES 1920
Cdd:PRK03918  534 LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYN 602

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1921 EMKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKI 1999
Cdd:PRK03918  603 EYLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSREL 675

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 530374448 2000 SALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2052
Cdd:PRK03918  676 AGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 599-1194 4.83e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 4.83e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   599 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 678
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   679 AKEISNLNQLIEEFKKNADNNssaftaLSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLL 758
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDK------IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   759 TEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL-------EGAERVRHISSKVEELSQA 831
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMaaiqgknESLEKVSSLTAQLESTKEM 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   832 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKE 911
Cdd:pfam15921  477 LRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   912 QVEEDNEVSSGLKQNYDEMSP----------AGQISKEELQ----------HEFDLLKKENEQRKRKLQAAL----INRK 967
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEkeindrrlelQEFKILKDKKDAKIRELEARVsdleLEKV 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   968 ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY---LKQTISEKEVELQHIRKDL 1044
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTtnkLKMQLKSAQSELEQTRNTL 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1045 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEisenqaiIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKP 1124
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK-------IQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1125 ELEEKILALEkekeqlQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1194
Cdd:pfam15921  789 AGELEVLRSQ------ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPG 852
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 48-572 9.13e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 9.13e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEmkaqggtvlptepq 127
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL-------------- 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  128 sEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQpAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:COG1196   301 -EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL-EEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  208 QTQAEQAAQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEK 287
Cdd:COG1196   379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  288 MELEVAERKlsfhnLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNS 367
Cdd:COG1196   459 EALLELLAE-----LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  368 KLLQDKNEQA---------VQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQ 438
Cdd:COG1196   534 AAYEAALEAAlaaalqnivVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  439 KRVVELENEKGALLLSSIELEELK--AENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTF 516
Cdd:COG1196   614 RYYVLGDTLLGRTLVAARLEAALRraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448  517 SQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAP 572
Cdd:COG1196   694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE 749
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1803-2303 1.06e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.70  E-value: 1.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1803 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLKETAEEE 1882
Cdd:PRK03918  230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDE 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1883 KDDLEERLMNQLAELNGsIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE------EEKQQLVKEKTKVESEIRKEYLE 1956
Cdd:PRK03918  309 LREIEKRLSRLEEEING-IEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyEEAKAKKEELERLKKRLTGLTPE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1957 KIQGAQKEPGNKShaKELQELLKEKQQEVKQLQKDCIRYQEKISALER------------TVKALEFVQTESQKDLEITK 2024
Cdd:PRK03918  388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIE 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2025 ENLAQAVEHRKKAQAELASFKVLLddtqsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2104
Cdd:PRK03918  466 KELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGE 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2105 MQ------EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL----QENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKK 2174
Cdd:PRK03918  541 IKslkkelEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2175 werkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHdkqiweskaqtevqlqqkvcdtlqgenkell 2254
Cdd:PRK03918  621 --------LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY------------------------------- 661

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 530374448 2255 sqlEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2303
Cdd:PRK03918  662 ---EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1265-2143 5.41e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 5.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1265 GTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1344
Cdd:pfam02463  161 EAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1345 IagLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1424
Cdd:pfam02463  241 L--LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1425 LCEMKQKpeeigeesrakqqIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1504
Cdd:pfam02463  319 SEKEKKK-------------AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1505 LALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1584
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1585 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLR 1664
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1665 AEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1744
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1745 NQTNVTEEGTQSIPGETEEQDSLSMstrptcsesVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1824
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRK---------GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1825 EFSQTLENEKNTLLSQISTKDGELKMLQEEVT-KMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1903
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQeAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1904 YCQDVTDAQIKNElLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepgnKSHAKELQELLKEKQQ 1983
Cdd:pfam02463  777 AEEREKTEKLKVE-EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK--------EEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1984 EVKQLQKDCIRYQEKISALERTVKALEfvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNL 2063
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLL----KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2064 KLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2143
Cdd:pfam02463  924 KEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2602-2905 8.87e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 8.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2602 EEEVHRLSALFSSSQKRIAELEEelvcvQKEAAKKVGEIEDKLKK--------ELKHLHHDAGIMRNETETAEERVAELA 2673
Cdd:COG1196   185 EENLERLEDILGELERQLEPLER-----QAEKAERYRELKEELKEleaellllKLRELEAELEELEAELEELEAELEELE 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2674 RDLVEME-------QKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERD 2746
Cdd:COG1196   260 AELAELEaeleelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2747 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR----KS 2822
Cdd:COG1196   340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLerleRL 419

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2823 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEEL 2902
Cdd:COG1196   420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499


                  ...
gi 530374448 2903 RQE 2905
Cdd:COG1196   500 EAD 502
PTZ00121 PTZ00121
MAEBL; Provisional
 666-1193 3.27e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 3.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  666 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQ 743
Cdd:PTZ00121 1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  744 RRLDYESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 816
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  817 RVRHISSKVEELSQA--LSQKELEITKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 892
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  893 KTLKEqlnlLSRAEEAKKEQVEEDNEVssglKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 972
Cdd:PTZ00121 1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  973 VSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE 1052
Cdd:PTZ00121 1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1053 QFQAlvKQMNQTLQDKTNQIDLLQAEISENQaiiqklitsntdasdgdsvalvketvvisppctgssehwKPELEEKILA 1132
Cdd:PTZ00121 1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530374448 1133 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1193
Cdd:PTZ00121 1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1911-2652 8.43e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 8.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1911 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 1990
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1991 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2070
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2071 SNKESVKSQMKQKDEdlerrLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEnldstvtq 2150
Cdd:pfam02463  332 KEKEEIEELEKELKE-----LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-------- 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2151 LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWES 2230
Cdd:pfam02463  399 LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2231 KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQE 2310
Cdd:pfam02463  479 LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2311 ADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIV 2390
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2391 LEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRivgdyQQLEERHLSIILEKDQLIQEAAAENN 2470
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAES-----ELAKEEILRRQLEIKKKEQREKEELK 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2471 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDL 2550
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKE 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2551 RRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEvhrLSALFSSSQKRIAELEEELVCVQ 2630
Cdd:pfam02463  794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK---LEKLAEEELERLEEEITKEELLQ 870

                          730       740
                   ....*....|....*....|..
gi 530374448  2631 KEAAKKVGEIEDKLKKELKHLH 2652
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKE 892
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 129-1012 3.93e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 3.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   129 EEQLSKHDKSSTEEEMEIEKIKHKLQEKEELIStlqaQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQ 208
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEY----YQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   209 TQAEQAAQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKM 288
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   289 ELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKT--GQELQSACDALKDQN 366
Cdd:pfam02463  336 EIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELElkSEEEKEAQLLLELAR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   367 SKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEgtqaVTEENIASLQKRVVELEN 446
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL----LKETQLVKLQEQLELLLS 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   447 EKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVL 526
Cdd:pfam02463  492 RQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALT 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   527 LLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQmegeGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQAST 606
Cdd:pfam02463  572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLD----KATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESG 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   607 EHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLN 686
Cdd:pfam02463  648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   687 QLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLS 766
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   767 IEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLL 846
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDE 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   847 LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQN 926
Cdd:pfam02463  888 LESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLL 967

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   927 YDEMSPAG------QISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGE 1000
Cdd:pfam02463  968 AKEELGKVnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLELGGSAE 1047

                          890
                   ....*....|..
gi 530374448  1001 VEEDKENKEYSE 1012
Cdd:pfam02463 1048 LRLEDPDDPFSG 1059
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1788-2026 5.60e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 5.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1788 AVSKDFSSHDEINNYLQQIDQLKERIAgleeEKQKNKEFSQTLENEKNTLLSQISTKDGELkmlqeEVTKMNLLNQQIQE 1867
Cdd:NF012221 1536 ATSESSQQADAVSKHAKQDDAAQNALA----DKERAEADRQRLEQEKQQQLAAISGSQSQL-----ESTDQNALETNGQA 1606

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1868 ELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGN-YCQDVTDAQIKNelLESEMKNLKKCVSE-LEEEKQQLVKEK 1943
Cdd:NF012221 1607 QRDAILEESRAVTKELTTLAQGLdaLDSQATYAGESGDqWRNPFAGGLLDR--VQEQLDDAKKISGKqLADAKQRHVDNQ 1684

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1944 TKVESEIRKEYLEKIQGAQKEPG-------NKSHAKELQELLKEKQQEVKQLQKDC-IRYQEKISALERTVKALEFVQTE 2015
Cdd:NF012221 1685 QKVKDAVAKSEAGVAQGEQNQANaeqdiddAKADAEKRKDDALAKQNEAQQAESDAnAAANDAQSRGEQDASAAENKANQ 1764

                         250
                  ....*....|.
gi 530374448 2016 SQKDLEITKEN 2026
Cdd:NF012221 1765 AQADAKGAKQD 1775
mukB PRK04863
chromosome partition protein MukB;
196-400 9.52e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.41  E-value: 9.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  196 EEFISTLQAQLSQ--TQAEQAAQKLRVLQRKLEEHEESL---------VGRAQVVDLLQQELTAAEQRnQILSQQLQQME 264
Cdd:PRK04863  441 EDWLEEFQAKEQEatEELLSLEQKLSVAQAAHSQFEQAYqlvrkiageVSRSEAWDVARELLRRLREQ-RHLAEQLQQLR 519

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  265 AEHNTLRNTVETEREESKILLE-KMELEVAErkLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQkhkaEMEEKTS 343
Cdd:PRK04863  520 MRLSELEQRLRQQQRAERLLAEfCKRLGKNL--DDEDELEQLQEELEARLESLSESVSEARERRMALRQ----QLEQLQA 593

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 530374448  344 HILSLQKTGQELQSACDALKDqnsklLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 400
Cdd:PRK04863  594 RIQRLAARAPAWLAAQDALAR-----LREQSGEEFEDSQDVTEYMQQLLERERELTV 645
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 57-290 3.09e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.59  E-value: 3.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   57 AEQLVVELKDIIRQKDVQLQQKDEALQ------EERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEP-QSE 129
Cdd:PRK10929   25 EKQITQELEQAKAAKTPAQAEIVEALQsalnwlEERKGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVPPnMST 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  130 EQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEqpaqsstemeefvmMKQQLQEKEEFISTL------- 202
Cdd:PRK10929  105 DALEQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTE--------------ARRQLNEIERRLQTLgtpntpl 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  203 -QAQLSQTQAEQAAQKLRVLQRKLeeheeslvgrAQVVDLLQQELtaAEQRNQILSQQLQQMEAEHNTLRNTVETER-EE 280
Cdd:PRK10929  171 aQAQLTALQAESAALKALVDELEL----------AQLSANNRQEL--ARLRSELAKKRSQQLDAYLQALRNQLNSQRqRE 238

                         250
                  ....*....|
gi 530374448  281 SKILLEKMEL 290
Cdd:PRK10929  239 AERALESTEL 248
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2001-2170 6.91e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 41.52  E-value: 6.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2001 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2076
Cdd:NF033928   88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2077 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2133
Cdd:NF033928  165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 530374448 2134 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2170
Cdd:NF033928  245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1865-2737 2.31e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.31e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1865 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1934
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1935 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2007
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2008 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDdtqsEAARVLADNLKLKKELQSNKESVKS---QMKQKD 2084
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE----ELEAELEELESRLEELEEQLETLRSkvaQLELQI 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2085 EDLERRLEQAEEkHLKEKKNMQEKLDALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQ 2162
Cdd:TIGR02168  396 ASLNNEIERLEA-RLERLEDRRERLQQEIEEllKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2163 DDRDRVIDEAKKWERKFsDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELkinISRLEHDKQiWESKAQTEVQ--LQQ 2240
Cdd:TIGR02168  475 QALDAAERELAQLQARL-DSLERLQENLEGFSEGVKALLKNQSGLSGILGVL---SELISVDEG-YEAAIEAALGgrLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2241 KVCDTLQGENKELlsqleetrhlYHSSQNELAKLE-SELKSLKDQlTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK-- 2317
Cdd:TIGR02168  550 VVVENLNAAKKAI----------AFLKQNELGRVTfLPLDSIKGT-EIQGNDREILKNIEGFLGVAKDLVKFDPKLRKal 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2318 ---FSYEQLETDLQASRELTSRLHEEINM--KEQKIIS---LLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENI 2389
Cdd:TIGR02168  619 sylLGGVLVVDDLDNALELAKKLRPGYRIvtLDGDLVRpggVITGGSAKTNSSILERRR----EIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2390 VLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAEN 2469
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2470 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLlevqlqqnKELENKYAKLEEKLKESEEANED 2549
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAANLRERLESLERRIAA 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2550 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEgtlglyhaqLKVKEEEVHRLSALFSSSQKRIAELEEELvcv 2629
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALALLRSELEELSEEL--- 903

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2630 qKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKENKGLTAQIQSFGRSMS 2705
Cdd:TIGR02168  904 -RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDEEEARRRLKRLENKIK 982

                          890       900       910
                   ....*....|....*....|....*....|..
gi 530374448  2706 SLQNSRDHANEELDELKRKYDASLKELAQLKE 2737
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1317-2144 2.52e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.52e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1317 IESLKTVSHEAEVHAEsLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQ 1396
Cdd:TIGR02168  202 LKSLERQAEKAERYKE-LKAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1397 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLA 1473
Cdd:TIGR02168  280 EEEIEELQKELYALANEIsrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE---LKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1474 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMdrsllenQSLSSSCESLKLALEGLTEDKEKLVKE 1553
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI-------ERLEARLERLEDRRERLQQEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1554 IESLKSSKIAESTEwqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEaeq 1633
Cdd:TIGR02168  430 LEEAELKELQAELE------ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN--- 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1634 emeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGDtakecmetLLSSNASMKEELERVkmeyetLSKKFQSLMSEk 1713
Cdd:TIGR02168  501 ------------LEGFSEGVKALLKNQSGLSGILGVLSE--------LISVDEGYEAAIEAA------LGGRLQAVVVE- 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1714 dSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQtnvteegtqsIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSkDF 1793
Cdd:TIGR02168  554 -NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTE----------IQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS-YL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1794 SSH----DEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENEKNTllSQISTKDGELKMLQEEVTKMNLLNQQIQE 1867
Cdd:TIGR02168  622 LGGvlvvDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAKTN--SSILERRREIEELEEKIEELEEKIAELEK 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1868 ELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1947
Cdd:TIGR02168  699 ALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1948 SEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKEN 2026
Cdd:TIGR02168  775 EEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE-------RRLEDLEEQ 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2027 LAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNKESVKSQMKQKDEDLerrleqaeekhlkekKNMQ 2106
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEALALLRSELEELSEEL---------------RELE 907

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 530374448  2107 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENL 2144
Cdd:TIGR02168  908 SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1266-2051 4.68e-18

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 92.05  E-value: 4.68e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1266 TSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGL-EIESLKTVSHEAEVHAESLQQKLESSQLQ 1344
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1345 iaglehLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1421
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1422 QVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARGTIERLTKSLADVESQ 1490
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1491 VSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGL--------------------------- 1543
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtvaqlgsvgeryataievaagnrln 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1544 ---TEDKEKLVKEIESLKSSKIAEST-----EWQEKHKELQKEYE-----ILL------QSYENVSNEAERIQHVVEAVr 1604
Cdd:TIGR02169  551 nvvVEDDAVAKEAIELLKRRKAGRATflplnKMRDERRDLSILSEdgvigFAVdlvefdPKYEPAFKYVFGDTLVVEDI- 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1605 QEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMrkFAKSKQQKILELEEENDRLRAEVhpagdtakecmetllss 1684
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGIL--FSRSEPAELQRLRERLEGLKREL----------------- 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1685 nASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEatekhdnqtnvteegtqsipgetEEQ 1764
Cdd:TIGR02169  691 -SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE-----------------------EDL 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1765 DSLSmstrptcsesvpsaksanpavskdfsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTllSQISTK 1844
Cdd:TIGR02169  747 SSLE----------------------------QEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEI 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1845 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKN 1924
Cdd:TIGR02169  797 QAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1925 LKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR---------- 1994
Cdd:TIGR02169  873 LEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeels 952

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1995 ---YQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDT 2051
Cdd:TIGR02169  953 ledVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 723-1497 6.71e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.71e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   723 VTELRAQVKQLEMNLAEAERQRRLdyesqtaHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 802
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKEL-------KAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEE 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   803 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLN 882
Cdd:TIGR02168  268 KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELA----EELAELE 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   883 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiskeeLQHEFDLLKKENEQRKRKLQAA 962
Cdd:TIGR02168  344 EKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-----------LELQIASLNNEIERLEARLERL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   963 LINRKELLQRVSRLEEELANL-KDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTiSEKEVELQHIR 1041
Cdd:TIGR02168  413 EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA-ERELAQLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1042 KDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQ-----------AIIQKLITSNTDASDGDSVALVKE--- 1107
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaalgGRLQAVVVENLNAAKKAIAFLKQNelg 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1108 TVVISPPCTGSSEHWKPELEEKI----------LALEKEKEQLQKKLQ---------EALTSRKAILKKAQEKER----- 1163
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILkniegflgvaKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKLRPGYRivtld 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1164 -----------------------------HLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESidgklpS 1214
Cdd:TIGR02168  652 gdlvrpggvitggsaktnssilerrreieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL------S 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1215 TDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshseDASALQGGTSVAQIKAQLKEIEAEKVELELKV----- 1289
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTEL---------EAEIEELEERLEEAEEELAEAEAEIEELEAQIeqlke 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1290 --SSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEH--------LRELQPKLD 1359
Cdd:TIGR02168  797 elKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAeieeleelIEELESELE 876

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1360 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQ------------LQVELCE 1427
Cdd:TIGR02168  877 ALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLA-QLELRLEGLEVridnlqerlseeYSLTLEE 955

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530374448  1428 MKQKPEEIGEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKE 1497
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 727-1610 1.89e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 1.89e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   727 RAQVKQLEMNLAEAERQ-RRLDYESQTAHDNL-LTEQIHSLSIEAKSKDvkIEVLQNELDDVQLQFSEQSTLIRSLQSQL 804
Cdd:TIGR02168  185 RENLDRLEDILNELERQlKSLERQAEKAERYKeLKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   805 QNKESEvlegaervrhisskveelsqaLSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLNEE 884
Cdd:TIGR02168  263 QELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   885 KFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAgqisKEELQHEFDLLKKENEQRKRKLQAALI 964
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   965 NRKELLQRVSRLEEELANLKDESKKEiplsETERGEVEEDKENKEYSEkcvtskcqeieiyLKQTISEKEVELQHIRKDL 1044
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQEEL 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1045 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASdgdSVALVKETVVISPPCTGSSEHWKP 1124
Cdd:TIGR02168  457 ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK---ALLKNQSGLSGILGVLSELISVDE 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1125 ELEEKILALekekeqLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIGDQL 1197
Cdd:TIGR02168  534 GYEAAIEAA------LGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVAKDL 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1198 RQLQIQVRESIDGKLpstdqqescsSTPGLEEPLFKATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQIKA 1273
Cdd:TIGR02168  608 VKFDPKLRKALSYLL----------GGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1274 QLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRE 1353
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1354 lqpkldELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALhtqlemqakehDERIKQLQVELCEMKqkpE 1433
Cdd:TIGR02168  758 ------ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKAL-----------REALDELRAELTLLN---E 817

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1434 EIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERD 1513
Cdd:TIGR02168  818 EAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELE 897

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1514 KLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEstewqekhkELQKEYEILLQSYENVSNEA 1593
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIEDDE 967

                          890
                   ....*....|....*..
gi 530374448  1594 ERIQHVVEAVRQEKQEL 1610
Cdd:TIGR02168  968 EEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1980-2748 2.10e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.12  E-value: 2.10e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1980 EKQQEVKQLQKDC----IRYQEKISALERTVKALEFVQTESQkdLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEA 2055
Cdd:TIGR02168  199 ERQLKSLERQAEKaeryKELKAELRELELALLVLRLEELREE--LEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2056 ARVLADNLKLKKELQSnkesvksqMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDK 2135
Cdd:TIGR02168  277 SELEEEIEELQKELYA--------LANEISRLEQQKQILRER----LANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2136 EVQQLQENLDStvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEirlkedncSVLKDQLRQMSIHMEELK 2215
Cdd:TIGR02168  345 KLEELKEELES---LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI--------ASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2216 INISRLEHDKQIWESKAQ-TEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEK 2294
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2295 CKEQKGNLEGIIRQQEADIQN-SKFSY------EQLETDLQASRELTSRLHEEINM-------KEQKIISLLSgKEEAIQ 2360
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNqSGLSGilgvlsELISVDEGYEAAIEAALGGRLQAvvvenlnAAKKAIAFLK-QNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2361 VAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETL--KTIKKENIQQKAQL--------------- 2423
Cdd:TIGR02168  573 VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlgGVLVVDDLDNALELakklrpgyrivtldg 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2424 -------------DSFVKSMSSLQNDRDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSEN 2490
Cdd:TIGR02168  653 dlvrpggvitggsAKTNSSILERRREIEELEEKIEELEEK----IAELEKALAELRKELEELEEELEQLRKELEELSRQI 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2491 AKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQN-------------KELENKYAKLEEKLKESEEANEDLRRSFNAL 2557
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerleeaeeelAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2558 QEEKQDLSKEIESLKVSISQLTRQVTALQEEgtLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqkeaaKKV 2637
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERR--LEDLEEQIEELSEDIESLAAEIEELEELIEELESEL--------EAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2638 GEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFgrsmssLQNSRDHANEE 2717
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL------QERLSEEYSLT 952

                          810       820       830
                   ....*....|....*....|....*....|..
gi 530374448  2718 LDELKRKYDASLKELAQLKEQ-GLLNRERDAL 2748
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRlKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1270-2151 7.19e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.11  E-value: 7.19e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1270 QIKAQLKEIE-----AEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1344
Cdd:TIGR02168  217 ELKAELRELElallvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1345 IAGLEH-LRELQPKLDELQKLISKKEEdvsylsgQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQv 1423
Cdd:TIGR02168  297 ISRLEQqKQILRERLANLERQLEELEA-------QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE- 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1424 elcEMKQKPEEigeesrakqqiqrkLQAALISRKEALKEnksLQEELSLARGTIERLTKSLADVESqvsaqnkekdtvlg 1503
Cdd:TIGR02168  369 ---ELESRLEE--------------LEEQLETLRSKVAQ---LELQIASLNNEIERLEARLERLED-------------- 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1504 RLALLQEERDKLITEMDRSllENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQkEYEILL 1583
Cdd:TIGR02168  415 RRERLQQEIEELLKKLEEA--ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1584 QSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL 1663
Cdd:TIGR02168  492 DSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELG 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1664 RAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLkhqiegnvsKQANLEATEKH 1743
Cdd:TIGR02168  572 RVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDL---------DNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1744 DNQTNVTEEGTQSIPGETeeqdslsmstrptcsesvpSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKN 1823
Cdd:TIGR02168  643 PGYRIVTLDGDLVRPGGV-------------------ITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1824 KEFSQTLENEKNTLLSQISTKDGELKMLQEEV----TKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQLAELNG 1899
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLarleAEVEQLEERIAQLSKELTELEAEIEELEERLEE-AEEELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1900 SIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLK 1979
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1980 EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEIT-------KENLAQAVEHRKKAQAELASFKVLLDDTQ 2052
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELeskrselRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2053 SEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ---------AEEKHLKEKKN-MQEKLDALRREKVHLEET 2122
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaaiEEYEELKERYDfLTAQKEDLTEAKETLEEA 1022

                          890       900       910
                   ....*....|....*....|....*....|
gi 530374448  2123 IGEI-QVTLNKKDKEVQQLQENLDSTVTQL 2151
Cdd:TIGR02168 1023 IEEIdREARERFKDTFDQVNENFQRVFPKL 1052
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2083-2919 7.96e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 84.72  E-value: 7.96e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2083 KDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLN------KKDKEVQQLQENLDSTvtQLAAF 2154
Cdd:TIGR02168  153 KPEERRAIFEEAAgiSKYKERRKETERKLERTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELREL--ELALL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2155 TKSMSSLQDDRDRVIDEAKKWERKFSDA---IQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESK 2231
Cdd:TIGR02168  231 VLRLEELREELEELQEELKEAEEELEELtaeLQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2232 AQTEVQLQQKVCDTLQgenkELLSQLEETrhlyhssQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2311
Cdd:TIGR02168  311 LANLERQLEELEAQLE----ELESKLDEL-------AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEE 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2312 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQ----VAIAELRQQHDKEIKELENLLSQEeee 2387
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKkleeAELKELQAELEELEEELEELQEEL--- 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2388 nivleeenkkavdktNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsiilekdqlIQEAAA 2467
Cdd:TIGR02168  457 ---------------ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG------------FSEGVK 509

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2468 ENNKLKEEIRGLRSHMDDLNSENAKLDAEL-IQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEA 2546
Cdd:TIGR02168  510 ALLKNQSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGN 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2547 NEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQV-------TALQ-----------------------------EEGT 2590
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvddldNALElakklrpgyrivtldgdlvrpggvitggsAKTN 669

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2591 LGLYHAQLKVKE--EEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETETAEER 2668
Cdd:TIGR02168  670 SSILERRREIEEleEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL-SRQISALRKDLARLEAEVEQLEER 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2669 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDAL 2748
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLES 828

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2749 LSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqr 2828
Cdd:TIGR02168  829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELS-------- 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2829 saaqpstspAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELhpLKAQLQEYQDKTKAFQIMQEELRQENLS 2908
Cdd:TIGR02168  901 ---------EELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYSLTLEEAEALENKIEDDEEE 969

                          890
                   ....*....|.
gi 530374448  2909 WQHELHQLRME 2919
Cdd:TIGR02168  970 ARRRLKRLENK 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1268-2137 2.60e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 83.19  E-value: 2.60e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1268 VAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQgLEIESLKTVSHEAEVHA-----ESLQQKLESSQ 1342
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKREYEGYEllkekEALERQKEAIE 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1343 LQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEK-EAALTKIQTEIIEQEDLIKALHTQL---EMQAKEHDER 1417
Cdd:TIGR02169  244 RQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIaekERELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1418 IKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEalkenkslqeELSLARGTIERLTKSLADVESQVSAQNKE 1497
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE----------ELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1498 KDTvlgrlalLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDkeklVKEIESLKSSKIAESTEWQEKHKELQK 1577
Cdd:TIGR02169  394 LEK-------LKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAK----INELEEEKEDKALEIKKQEWKLEQLAA 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1578 EYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELE 1657
Cdd:TIGR02169  463 DLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIE 542

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1658 -EENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVqDLKHQIEgNVSKQA- 1735
Cdd:TIGR02169  543 vAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLV-EFDPKYE-PAFKYVf 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1736 -------NLEATEKH-DNQTNVTEEGtqsipgeteeqDSLSMSTRPTCSESVPSAKSANPAvskdfsshdeinNYLQQID 1807
Cdd:TIGR02169  621 gdtlvveDIEAARRLmGKYRMVTLEG-----------ELFEKSGAMTGGSRAPRGGILFSR------------SEPAELQ 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1808 QLKERIAGLEEEKQKNKEFSQTLENEKNTLLS-------QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1880
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIENRLDELSQelsdasrKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1881 EEKDDLEERlmnqLAELNGSIGNYCQDVTDaqIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQG 1960
Cdd:TIGR02169  758 SELKELEAR----IEELEEDLHKLEEALND--LEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1961 AQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAE 2040
Cdd:TIGR02169  832 EKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2041 LASFKVLLDDTQsEAARVLADNLK----LKKELQSNKESVKS--QMKQKDEDLERRLEQAE----------EKHLKEKKN 2104
Cdd:TIGR02169  912 IEKKRKRLSELK-AKLEALEEELSeiedPKGEDEEIPEEELSleDVQAELQRVEEEIRALEpvnmlaiqeyEEVLKRLDE 990

                          890       900       910
                   ....*....|....*....|....*....|...
gi 530374448  2105 MQEKLDALRREKVHLEETIGEiqvtLNKKDKEV 2137
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEE----YEKKKREV 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1796-2493 4.09e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 4.09e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1796 HDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKL 1875
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1876 KETAEEEKDDLEERLMNQLAELNGS---IGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1952
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELeekLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1953 EYLE-KIQGAQKEPGNKSHAKELQELLK-EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTEsqkdLEITKENLAQA 2030
Cdd:TIGR02168  398 LNNEiERLEARLERLEDRRERLQQEIEElLKKLEEAELKELQAELEELEEELEELQEELERLEEA----LEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2031 VEHRKKAQAELASFKVLLDDTQSEAARVL-----ADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK----E 2101
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEgfsegVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavvvE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2102 KKNMQEK-LDALRREKVH----LEETI---GEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSL------QDDRDR 2167
Cdd:TIGR02168  554 NLNAAKKaIAFLKQNELGrvtfLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2168 VIDEAKKW-----------------------ERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLE-- 2222
Cdd:TIGR02168  634 ALELAKKLrpgyrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEee 713

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2223 ---------------HDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTD 2287
Cdd:TIGR02168  714 leqlrkeleelsrqiSALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2288 LSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLlsgkeeaiQVAIAELR 2367
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL--------AAEIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2368 QQHDKEIKELENLLSQEEEENIVLEEENKKAvdktNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2447
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSEL----EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 530374448  2448 EERhlsiILEKDQLIQEAAAEN-NKLKEEIRGLRSHMDDLNSENAKL 2493
Cdd:TIGR02168  942 QER----LSEEYSLTLEEAEALeNKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 191-983 7.44e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 7.44e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   191 QLQEKEEFISTLQAQL--SQTQAEQAAQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHN 268
Cdd:TIGR02168  233 RLEELREELEELQEELkeAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   269 TLRNT---VETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHkaemeektshi 345
Cdd:TIGR02168  313 NLERQleeLEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL----------- 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   346 lslqktgQELQSACDALKDQNSKLlqdkNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSfpdvynEG 425
Cdd:TIGR02168  382 -------ETLRSKVAQLELQIASL----NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL------EE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   426 TQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEA-QNRTGEADREVSEI------------- 491
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlQENLEGFSEGVKALlknqsglsgilgv 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   492 --SIVDIANKRSSSAE----ESGQDVLENTFSQKHKELSVLLlemKEAQEEIAFLKLQLQGKRAEEADHEVLdQKEMKQM 565
Cdd:TIGR02168  525 lsELISVDEGYEAAIEaalgGRLQAVVVENLNAAKKAIAFLK---QNELGRVTFLPLDSIKGTEIQGNDREI-LKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   566 EGEGIAPIKMKVFLEDTGQDFplmpneESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKS-----TKQDGDKSLSAvp 640
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRpggviTGGSAKTNSSI-- 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   641 digQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL 720
Cdd:TIGR02168  673 ---LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   721 SmvtelrAQVKQLEMNLAEAERQRrldyesqtahdNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSL 800
Cdd:TIGR02168  746 E------ERIAQLSKELTELEAEI-----------EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   801 QSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISF---SMTEK 877
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNeraSLEEA 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   878 MVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMspAGQISkEELQHEFDLLKKENEQRKR 957
Cdd:TIGR02168  889 LALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLS-EEYSLTLEEAEALENKIED 965

                          810       820
                   ....*....|....*....|....*.
gi 530374448   958 KLQaalinrkELLQRVSRLEEELANL 983
Cdd:TIGR02168  966 DEE-------EARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1802-2585 1.22e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 1.22e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1802 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEE 1881
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1882 EKDDLEerlmNQLAELNGSIgnycqdvtdaqiknELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEylekiqgA 1961
Cdd:TIGR02168  310 RLANLE----RQLEELEAQL--------------EELESKLDELAEELAELEEKLEELKEELESLEAELEEL-------E 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1962 QKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqTESQKDLEITKENLAQAVEHRKKA-QAE 2040
Cdd:TIGR02168  365 AELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DRRERLQQEIEELLKKLEEAELKElQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2041 LASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKS------QMKQKDEDLERRLEQAEEKHLKEKKNMQEKLD---- 2110
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAaerelaQLQARLDSLERLQENLEGFSEGVKALLKNQSGlsgi 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2111 -ALRREKVH--------LEETIGE-----IQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRD---------- 2166
Cdd:TIGR02168  522 lGVLSELISvdegyeaaIEAALGGrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDReilkniegfl 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2167 RVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLkDQLRQM------------------SIHMEELKINISRLEHDKQIW 2228
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNAL-ELAKKLrpgyrivtldgdlvrpggVITGGSAKTNSSILERRREIE 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2229 ESKAQtevqlqqkvCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ 2308
Cdd:TIGR02168  681 ELEEK---------IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2309 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQQHDKEIKELENLLSQEEEEN 2388
Cdd:TIGR02168  752 LSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI--------EQLKEELKALREALDELRAELTLLNEEAANLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2389 IVLEEENKKAVDKTNQLMETLKTIKKENIQQK---AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQL---I 2462
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIEslaAEIEELEELIEELESELEALLNERASLEEALALLRSELEELseeL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2463 QEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLN--QVITIKDSQQKQLLEVQLQQN-----KELENKYAK 2535
Cdd:TIGR02168  904 RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSeeYSLTLEEAEALENKIEDDEEEarrrlKRLENKIKE 983

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 530374448  2536 LEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2585
Cdd:TIGR02168  984 LGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1798-2343 1.29e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.28  E-value: 1.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1798 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVtkmNLLNQQIQEELSRVTKLKE 1877
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE---YELLAELARLEQDIARLEE 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1878 TAEEEKDDLEeRLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 1957
Cdd:COG1196   310 RRRELEERLE-ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1958 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKA 2037
Cdd:COG1196   389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2038 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALR 2113
Cdd:COG1196   469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAAL 548

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2114 REKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2193
Cdd:COG1196   549 QNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLV 628

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2194 EDNC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHS 2266
Cdd:COG1196   629 AARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530374448 2267 SQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLhEEINM 2343
Cdd:COG1196   709 LAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL-GPVNL 784
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1334-1901 2.18e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 76.90  E-value: 2.18e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1334 LQQKLESSQLQIAGLeHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1413
Cdd:COG1196   218 LKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE 296

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1414 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1493
Cdd:COG1196   297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1494 QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAEstewQEKHK 1573
Cdd:COG1196   377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1574 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETE------KQLQEAEQEMEEMKEKMRKFAK 1647
Cdd:COG1196   453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvKAALLLAGLRGLAGAVAVLIGV 532

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1648 SKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLM----------SEKDSLS 1717
Cdd:COG1196   533 EAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGaigaavdlvaSDLREAD 612

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1718 EEVQDLKHQIEGNVSKQANLEATEKHDNQTN-----VTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKD 1792
Cdd:COG1196   613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAgrlreVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1793 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRV 1872
Cdd:COG1196   693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 530374448 1873 TKLKE-------TAEEEKDDLEER---LMNQLAELNGSI 1901
Cdd:COG1196   773 EREIEalgpvnlLAIEEYEELEERydfLSEQREDLEEAR 811
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1270-1559 7.29e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 7.29e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1270 QIKAQLKEIEAEKVELELKvssttsELTKKSEEvfqLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGL- 1348
Cdd:COG1196   217 ELKEELKELEAELLLLKLR------ELEAELEE---LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAq 287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1349 EHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1428
Cdd:COG1196   288 AEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1429 KQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALL 1508
Cdd:COG1196   368 LEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 530374448 1509 QEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS 1559
Cdd:COG1196   448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 758-1728 7.38e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 7.38e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   758 LTEQIHSLSIEAKsKDVKIEVLQNELDDVQLQFSEQStlIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKEL 837
Cdd:TIGR02168  198 LERQLKSLERQAE-KAERYKELKAELRELELALLVLR--LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   838 EITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDN 917
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   918 EVSSGLKQNYDEMSPAgqisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEiplsETE 997
Cdd:TIGR02168  351 EELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL----QQE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   998 RGEVEEDKENKEYSEkcvtskcqeieiyLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQA 1077
Cdd:TIGR02168  423 IEELLKKLEEAELKE-------------LQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1078 EISENQAIIQKLITSNTDASdgdSVALVKETVVISPPCTGSSEHWKPELEEKILALekekeqLQKKLQEALTSRKAILKK 1157
Cdd:TIGR02168  490 RLDSLERLQENLEGFSEGVK---ALLKNQSGLSGILGVLSELISVDEGYEAAIEAA------LGGRLQAVVVENLNAAKK 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1158 AQEkerhlreelkqqkddynrlqeqFDEQSKenenigdqLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLfkateq 1237
Cdd:TIGR02168  561 AIA----------------------FLKQNE--------LGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVA------ 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1238 hhtqpvleSNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTseltkkseevfqlqEQINKQGLei 1317
Cdd:TIGR02168  605 --------KDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDG--------------DLVRPGGV-- 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1318 eslkTVSHEAEVHAESLQQKLEssqlqiaglehLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQE 1397
Cdd:TIGR02168  661 ----ITGGSAKTNSSILERRRE-----------IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS 725

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1398 DLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqaalisrKEALKENKSLQEELSLARGTI 1477
Cdd:TIGR02168  726 RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-------AEAEAEIEELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1478 ERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESL 1557
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1558 ksskiaestewQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEkqlqeaeqemee 1637
Cdd:TIGR02168  879 -----------LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLE------------ 935

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1638 mkekmrkfakskqqkiLELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKM--------------EYETLS 1703
Cdd:TIGR02168  936 ----------------VRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaaieEYEELK 999

                          970       980
                   ....*....|....*....|....*
gi 530374448  1704 KKFQSLMSEKDSLSEEVQDLKHQIE 1728
Cdd:TIGR02168 1000 ERYDFLTAQKEDLTEAKETLEEAIE 1024
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2418-3151 2.14e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 2.14e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2418 QQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE---ERHLSIILEKDQLIQEA-------AAENNKLKEEIRGLRSHMDDLN 2487
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEeklEELRLEVSELEEEIEELqkelyalANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2488 SENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQ------LQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEK 2561
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2562 QDLSKEIESLKVSISQLTRQVTALQEE-----------------GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE 2624
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEAEQ 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2625 ELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK 2688
Cdd:TIGR02168  476 ALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2689 ENKGLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQglLNRERDALLSETAFSMNSTE 2760
Cdd:TIGR02168  556 NAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPK--LRKALSYLLGGVLVVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2761 ENSLSHLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFRkseegkqrsaaqpstspAEV 2840
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEELE-----------------EKI 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2841 QSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTkAFQIMQEELRQENLSWQHELHQLRMEK 2920
Cdd:TIGR02168  694 AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2921 SSWEIHERRMKEQYLMAisDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdGSQNLVYETELLRTQLND 3000
Cdd:TIGR02168  773 AEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLED 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  3001 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNIDvap 3080
Cdd:TIGR02168  843 LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRRE--- 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530374448  3081 gapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSVAEEQIRRLE 3151
Cdd:TIGR02168  917 ----------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1929-2753 2.39e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.56  E-value: 2.39e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1929 VSELEEEKQQLVKEKTKVESEIRKEYL---EKIQGAQKEPGNKSHAKELQELLKEKQQ-EVKQLQKDCIRYQEKISALER 2004
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLiidEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2005 TVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAsfkvllDDTQSEAARVLADNLKLKKELQSNKESVKSQmKQKD 2084
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK------DLGEEEQLRVKEKIGELEAEIASLERSIAEK-EREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2085 EDLERRLEQAEE---KHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK-------KDKEVQQLQENLDSTVTQLAAF 2154
Cdd:TIGR02169  318 EDAEERLAKLEAeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDlraeleeVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2155 TKSMSSLQDDRDRVIDEAKKWERKFSDAiqskEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQT 2234
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADL----NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2235 EVQLQQKVCDTLQGENKElLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQ---------KGNLEGI 2305
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRE-LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaaGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2306 IRQQEADIQN----------SKFSYEQLeTDLQASRELTSRLHE-----------EINMKEQKII-----------SLLS 2353
Cdd:TIGR02169  553 VVEDDAVAKEaiellkrrkaGRATFLPL-NKMRDERRDLSILSEdgvigfavdlvEFDPKYEPAFkyvfgdtlvveDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2354 GKEEAIQVAIAELrqqhDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKEniqqkaqLDSFVKSMSSL 2433
Cdd:TIGR02169  632 ARRLMGKYRMVTL----EGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRE-------LSSLQSELRRI 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2434 QNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE---EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITI 2510
Cdd:TIGR02169  701 ENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEEleeDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2511 KDSQQKQLLEVQLQqnkELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-- 2588
Cdd:TIGR02169  781 LNDLEARLSHSRIP---EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEie 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2589 ---GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqKEAAKKVGEIEDKLKKELKHLhhdaGIMRNETETA 2665
Cdd:TIGR02169  858 nlnGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL----RELERKIEELEAQIEKKRKRL----SELKAKLEAL 929

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2666 EERVAELARDLVEMEQKLLMVTKENKgLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEqgllnrER 2745
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIPEEELSLED-VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEE------ER 1002


                   ....*...
gi 530374448  2746 DALLSETA 2753
Cdd:TIGR02169 1003 KAILERIE 1010
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1534-2342 9.34e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 71.63  E-value: 9.34e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1534 ESLKLALegLTEDKEKLVKEIESLKSSKIAESTEW---QEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQEL 1610
Cdd:TIGR02168  223 RELELAL--LVLRLEELREELEELQEELKEAEEELeelTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1611 YGKLRSTEANKKETEKQLQEAEQEMEEMkekmrkfakskQQKILELEEENDRLRAEVhpagDTAKECMETLLSSNASMKE 1690
Cdd:TIGR02168  301 EQQKQILRERLANLERQLEELEAQLEEL-----------ESKLDELAEELAELEEKL----EELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1691 ELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEAtEKHDNQTNVTEEGTQSIPGETEEQDSLSMS 1770
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED-RRERLQQEIEELLKKLEEAELKELQAELEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1771 TRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQ----QIDQLKERIAGLEEEKQKNKEFSQTLENEKN----------T 1836
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDaaerELAQLQARLDSLERLQENLEGFSEGVKALLKnqsglsgilgV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1837 LLSQISTKDG---------ELKMLQEEVTKMNLLNQQI----QEELSRVTKLKETAEEEkDDLEERLMNQLAELNGSIGn 1903
Cdd:TIGR02168  525 LSELISVDEGyeaaieaalGGRLQAVVVENLNAAKKAIaflkQNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1904 YCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHA---------KEL 1974
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1975 QELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASfkvlLDDTQSE 2054
Cdd:TIGR02168  683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2055 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2134
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2135 KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWerkfSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2214
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2215 KINISRL-EHDKQIWESKAQTEVQLQQkvcdTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSN--- 2290
Cdd:TIGR02168  914 RRELEELrEKLAQLELRLEGLEVRIDN----LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnl 989

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|...
gi 530374448  2291 -SLEKCKEQKGNLEgIIRQQEADIQNSKFSYEQLETDLqaSRELTSRLHEEIN 2342
Cdd:TIGR02168  990 aAIEEYEELKERYD-FLTAQKEDLTEAKETLEEAIEEI--DREARERFKDTFD 1039
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1129-1952 1.33e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.86  E-value: 1.33e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1129 KILALEKEKEQLQKKLQEALTSRKAILKKAQEKErhlrEELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREsi 1208
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI-- 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1209 dgklpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASAlqggtSVAQIKAQLKEIEAEKVELELK 1288
Cdd:TIGR02168  307 --------LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKE-----ELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1289 VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEhLRELQPKLDELQKLISKK 1368
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE-LKELQAELEELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1369 EEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMqAKEHDERIKQLQVELCEMKQKPEEI-GEESRAKQQIQR 1447
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLsGILGVLSELISV 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1448 K--------------LQAALISRKEALKENKSLQEELSLARGTIERLT-KSLADVESQVSAQNKEKDTVLGRLALLQEER 1512
Cdd:TIGR02168  532 DegyeaaieaalggrLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDsIKGTEIQGNDREILKNIEGFLGVAKDLVKFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1513 DKLITEMDRSLlenqSLSSSCESLKLALEGL----------TEDKEKL---------VKEIESLKSSKIAESTEWQEKHK 1573
Cdd:TIGR02168  612 PKLRKALSYLL----GGVLVVDDLDNALELAkklrpgyrivTLDGDLVrpggvitggSAKTNSSILERRREIEELEEKIE 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1574 ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKI 1653
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1654 LELEEENDRLrAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvsk 1733
Cdd:TIGR02168  768 ERLEEAEEEL-AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----- 841

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1734 qanlEATEKHDNQTNVTEEGTQSIPGETEEQDSLsmstrptcsesvpsaksanpavskdfssHDEINNYLQQIDQLKERI 1813
Cdd:TIGR02168  842 ----DLEEQIEELSEDIESLAAEIEELEELIEEL----------------------------ESELEALLNERASLEEAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1814 AGLEEEKQKnkefsqtLENEKNTLLSQISTKDGELKMLQEEVTKMNL----LNQQIQEELSRVTKLKETAEEEKDDLEER 1889
Cdd:TIGR02168  890 ALLRSELEE-------LSEELRELESKRSELRRELEELREKLAQLELrlegLEVRIDNLQERLSEEYSLTLEEAEALENK 962

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530374448  1890 LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1952
Cdd:TIGR02168  963 IEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 48-919 1.37e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.87  E-value: 1.37e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448    48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQkdeaLQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVlptepq 127
Cdd:TIGR02169  173 EKALEELEEVEENIERLDLIIDEKRQQLER----LRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAI------ 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   128 sEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFiSTLQAQLS 207
Cdd:TIGR02169  243 -ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAE-KERELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   208 QTQAEQAAQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEK 287
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   288 MElevaerklsfhNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNS 367
Cdd:TIGR02169  401 IN-----------ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   368 KLLQDKNEqavqsaqtIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAV---TEENIASLQKRVVEL 444
Cdd:TIGR02169  470 ELYDLKEE--------YDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAI 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   445 ENEKGAlllssiELEELKAENEKLSSQITLLEAQNRTGEAdrevSEISIVDIANKRSSSAEESGQDVLentfsqkhkELS 524
Cdd:TIGR02169  542 EVAAGN------RLNNVVVEDDAVAKEAIELLKRRKAGRA----TFLPLNKMRDERRDLSILSEDGVI---------GFA 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   525 VLLLEMKEAQEEIAFLKLQLQG-KRAEEADHEVLDQKEMKQMEGEGIAP---IKMKVFLEDTGQDFPLMPNEESSLPAVE 600
Cdd:TIGR02169  603 VDLVEFDPKYEPAFKYVFGDTLvVEDIEAARRLMGKYRMVTLEGELFEKsgaMTGGSRAPRGGILFSRSEPAELQRLRER 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   601 KEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAK 680
Cdd:TIGR02169  683 LEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   681 EISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKElsmvtELRAQVKQLEMNLAEAERQ-RRLDYESQTAHDnllt 759
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS-----KLEEEVSRIEARLREIEQKlNRLTLEKEYLEK---- 833

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   760 eqihslsiEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEI 839
Cdd:TIGR02169  834 --------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   840 TKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEkMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEV 919
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE-DEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEV 984
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 773-1614 2.02e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 2.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   773 DVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEvLEGAERVRHISSKVEELSQALSQKELEitKMDQLLLEKKRD 852
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLKEKE--ALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   853 VETLQQTIEEKDQQVTEISFSMTEKMVQLNE-----------EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSS 921
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEElnkkikdlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   922 GLKQNYDEMspagQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESK---KEIPLSETER 998
Cdd:TIGR02169  326 KLEAEIDKL----LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKdyrEKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   999 GEVEEDKENKEYSEKCVTSKCQEIEIYLKQtISEKEVELQHIRKDLEEKLAAEE----QFQALVKQMNQTLQDKTNQIDL 1074
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAAIAG-IEAKINELEEEKEDKALEIKKQEwkleQLAADLSKYEQELYDLKEEYDR 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1075 LQAEISENQAIIQKLITSNTDASD--GDSVALVKETVVISPPCTGSSEHWKPELEEKILALEK-----------EKEQLQ 1141
Cdd:TIGR02169  481 VEKELSKLQRELAEAEAQARASEErvRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVaagnrlnnvvvEDDAVA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1142 KKLQEALTSRKA------ILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKE--NENIGDQL--------RQLQIQVR 1205
Cdd:TIGR02169  561 KEAIELLKRRKAgratflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafKYVFGDTLvvedieaaRRLMGKYR 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1206 E-SIDGKLpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESnLCPDWPSHSEDASALQGGTS-----VAQIKAQLKEIE 1279
Cdd:TIGR02169  641 MvTLEGEL----FEKSGAMTGGSRAPRGGILFSRSEPAELQR-LRERLEGLKRELSSLQSELRrienrLDELSQELSDAS 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1280 AEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHlRELQPKLD 1359
Cdd:TIGR02169  716 RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA-RLSHSRIP 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1360 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIGEES 1439
Cdd:TIGR02169  795 EIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI----DLKEQIKSIEKEIENLNGKKEELEEEL 870

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1440 RAKQQIQRKLQAALISRKealKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERdklitem 1519
Cdd:TIGR02169  871 EELEAALRDLESRLGDLK---KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK------- 940

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1520 dRSLLENQSLSSSCESLKLALEGLTEDKEKL----VKEIESLKSSKiAESTEWQEKHKELQKEYEILLQSYENVSNEAER 1595
Cdd:TIGR02169  941 -GEDEEIPEEELSLEDVQAELQRVEEEIRALepvnMLAIQEYEEVL-KRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018

                          890       900
                   ....*....|....*....|
gi 530374448  1596 I-QHVVEAVRQEKQELYGKL 1614
Cdd:TIGR02169 1019 VfMEAFEAINENFNEIFAEL 1038
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1971-2571 2.47e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.97  E-value: 2.47e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1971 AKELQELLKEKQQEVKQLQKDciRYQEKISALERTVKALEfvqtesqkdleitkENLAQAVEHRKKAQAELASFKVLLDD 2050
Cdd:COG1196   215 YRELKEELKELEAELLLLKLR--ELEAELEELEAELEELE--------------AELEELEAELAELEAELEELRLELEE 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2051 TQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV 2128
Cdd:COG1196   279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERleELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2129 TLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRvideakkwerkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMS 2208
Cdd:COG1196   359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEEL 423

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2209 IHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDL 2288
Cdd:COG1196   424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2289 SNSLEKCKEQKGNLE-GIIRQQEADIQNSKFSYEQ-LETDLQASRELTSRLHEEInmkEQKIISLLSGKEEAiQVAIAEL 2366
Cdd:COG1196   504 EGFLEGVKAALLLAGlRGLAGAVAVLIGVEAAYEAaLEAALAAALQNIVVEDDEV---AAAAIEYLKAAKAG-RATFLPL 579

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2367 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLktikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQ 2446
Cdd:COG1196   580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL----LGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2447 LEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDsQQKQLLEVQLQQN 2526
Cdd:COG1196   656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL-EEEALEEQLEAER 734

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*
gi 530374448 2527 KELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESL 2571
Cdd:COG1196   735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 723-1084 3.35e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.58  E-value: 3.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  723 VTELRAQVKQLEmnlAEAERQRRldYesqtahdnllteqihsLSIEAKSKDVKIEVLQNELDDVQLQfseqstlIRSLQS 802
Cdd:COG1196   195 LGELERQLEPLE---RQAEKAER--Y----------------RELKEELKELEAELLLLKLRELEAE-------LEELEA 246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  803 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 882
Cdd:COG1196   247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELA 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  883 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRkLQAA 962
Cdd:COG1196   327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ-LEEL 405

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  963 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEysekcvtskcqeieiylkqtisEKEVELQHIRK 1042
Cdd:COG1196   406 EEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA----------------------ELEEEEEALLE 463

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 530374448 1043 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1084
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1459-2052 1.48e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.40  E-value: 1.48e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1459 ALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMD---RSLLENQSLSSSCES 1535
Cdd:PRK03918  163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1536 LKLALEGLTEDKEKL---VKEIESLKSSKIAESTEWQEKHKELQ------KEYEILLQSYENVSNEAERIQHVVEAVRQE 1606
Cdd:PRK03918  243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLSEFYEEYLDELREIEKRLSRLEEE 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1607 KQELYGKLRstEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPagdtakecmetllssna 1686
Cdd:PRK03918  323 INGIEERIK--ELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTG----------------- 383

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1687 smkEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEgnvSKQANLEATEKHDNQTNV-----TEEGTQSIPGET 1761
Cdd:PRK03918  384 ---LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIK---ELKKAIEELKKAKGKCPVcgrelTEEHRKELLEEY 457

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1762 EEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKEriagLEEE-KQKNKEFSQTLENEKNTLLSQ 1840
Cdd:PRK03918  458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE----LEEKlKKYNLEELEKKAEEYEKLKEK 533

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1841 ISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLES 1920
Cdd:PRK03918  534 LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYN 602

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1921 EMKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKI 1999
Cdd:PRK03918  603 EYLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSREL 675

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 530374448 2000 SALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2052
Cdd:PRK03918  676 AGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 647-1220 1.64e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.64e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  647 QDELERLKSQILELElnfhKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKelsmvtEL 726
Cdd:COG1196   238 EAELEELEAELEELE----AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------RL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  727 RAQVKQLEMNLAEAERQRrldyESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN 806
Cdd:COG1196   308 EERRRELEERLEELEEEL----AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  807 KESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKF 886
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEAELEEEEE 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  887 SLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEelqhefdllkKENEQRKRKLQAALInr 966
Cdd:COG1196   460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA----------ALLLAGLRGLAGAVA-- 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  967 kELLQRVSRLEEELANLKDESKKEIPLSETERGE--VEEDKENKEysekcvtskcqeieiyLKQTISEKEVELQHIRKDL 1044
Cdd:COG1196   528 -VLIGVEAAYEAALEAALAAALQNIVVEDDEVAAaaIEYLKAAKA----------------GRATFLPLDKIRARAALAA 590

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1045 EEKLAAEEQFQALVKQMNQTLQDK-TNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWK 1123
Cdd:COG1196   591 ALARGAIGAAVDLVASDLREADARyYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRREL 670

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1124 PELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQ 1203
Cdd:COG1196   671 LAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE 750

                         570
                  ....*....|....*..
gi 530374448 1204 VRESIDGKLPSTDQQES 1220
Cdd:COG1196   751 EALEELPEPPDLEELER 767
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1806-2588 3.16e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.63  E-value: 3.16e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1806 IDQLKERIAGLEEEKQKNKEFSQTLE-----------NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTK 1874
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKekreyegyellKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1875 LKETAEEEKDDLEERLMNQLaelngsignycqdvtdaQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEy 1954
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1955 lekiqgaqkepgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKENLAQAVEHR 2034
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD-------KEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2035 KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKsQMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRR 2114
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWK----LEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2115 EKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRV---IDEAKKWERKFSDAIQS------ 2185
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVaagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2186 -----------KEEEIRLKEDNCS--------VLKDQLRQMSIHMEE--LKINISRLEHDKQ-------------IWESK 2231
Cdd:TIGR02169  550 nnvvveddavaKEAIELLKRRKAGratflplnKMRDERRDLSILSEDgvIGFAVDLVEFDPKyepafkyvfgdtlVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2232 AQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEA 2311
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2312 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQqhdkEIKELENLLSQEEEenivl 2391
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL--------SSLEQEIENVKS----ELKELEARIEELEE----- 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2392 eeenkkavdKTNQLMETLKTIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQL---IQEAAAE 2468
Cdd:TIGR02169  773 ---------DLHKLEEALNDLEARLSHS--RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQELQEQ 841

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2469 NNKLKEEIRGLRSHMDDLNSENAKLDAELiqyredlnqvitikdsqqkqllevqlqqnKELENKYAKLEEKLKESEEANE 2548
Cdd:TIGR02169  842 RIDLKEQIKSIEKEIENLNGKKEELEEEL-----------------------------EELEAALRDLESRLGDLKKERD 892

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 530374448  2549 DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEE 2588
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 599-1194 4.83e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.91  E-value: 4.83e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   599 VEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEK 678
Cdd:pfam15921  243 VEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDL 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   679 AKEISNLNQLIEEFKKNADNNssaftaLSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLL 758
Cdd:pfam15921  323 ESTVSQLRSELREAKRMYEDK------IEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLE 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   759 TEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL-------EGAERVRHISSKVEELSQA 831
Cdd:pfam15921  397 KEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMaaiqgknESLEKVSSLTAQLESTKEM 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   832 LSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKE 911
Cdd:pfam15921  477 LRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   912 QVEEDNEVSSGLKQNYDEMSP----------AGQISKEELQ----------HEFDLLKKENEQRKRKLQAAL----INRK 967
Cdd:pfam15921  556 QMAEKDKVIEILRQQIENMTQlvgqhgrtagAMQVEKAQLEkeindrrlelQEFKILKDKKDAKIRELEARVsdleLEKV 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   968 ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY---LKQTISEKEVELQHIRKDL 1044
Cdd:pfam15921  636 KLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTtnkLKMQLKSAQSELEQTRNTL 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1045 EEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEisenqaiIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKP 1124
Cdd:pfam15921  716 KSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK-------IQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1125 ELEEKILALEkekeqlQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1194
Cdd:pfam15921  789 AGELEVLRSQ------ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPG 852
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 63-889 5.39e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 5.39e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448    63 ELKDIIRQKDVQLQQKD-EALQEERKAADNKIKKLKLHAKAKLTSLNKYieemkaqggtvlptepqsEEQLSKHDKSSTE 141
Cdd:TIGR02168  217 ELKAELRELELALLVLRlEELREELEELQEELKEAEEELEELTAELQEL------------------EEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   142 EEMEIEKIKHKLQEKEELISTLQAQLTQAQAE------QPAQSSTEMEEFvmmKQQLQEKEEFISTLQAQLSQTQAEQAA 215
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERlanlerQLEELEAQLEEL---ESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   216 Q---------KLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREE-SKILL 285
Cdd:TIGR02168  356 LeaeleeleaELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKlEEAEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   286 EKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTShILSLQKTGQELQSACDALKDQ 365
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   366 NSKLLQDKN------------EQAVQSA--QTIQQLEDQLQQKSKEISQFLnrlplQQHETASQTSFPdvynegtqaVTE 431
Cdd:TIGR02168  515 QSGLSGILGvlselisvdegyEAAIEAAlgGRLQAVVVENLNAAKKAIAFL-----KQNELGRVTFLP---------LDS 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   432 ENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQI--------TLLEAQNRTGEADREVSEISIV-DIANKRSS 502
Cdd:TIGR02168  581 IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvvdDLDNALELAKKLRPGYRIVTLDgDLVRPGGV 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   503 SAEESGQDVLeNTFSQKhKELSVLLLEMKEAQEEIAFLKLQLQgkRAEEADHEVLDQKEMKQMEGEGIapikmkvfledt 582
Cdd:TIGR02168  661 ITGGSAKTNS-SILERR-REIEELEEKIEELEEKIAELEKALA--ELRKELEELEEELEQLRKELEEL------------ 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   583 gqdfplmpNEESSLPAVEKEQASTEHQSRTSEEISLndagvelkstkqdgdkslsavpdigqchQDELERLKSQILELEL 662
Cdd:TIGR02168  725 --------SRQISALRKDLARLEAEVEQLEERIAQL----------------------------SKELTELEAEIEELEE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   663 NFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEErdqlLSQVKELsmVTELRAQVKQLEMNLAEAER 742
Cdd:TIGR02168  769 RLEEAEE----ELAEAEAEIEELEAQIEQLKEELKALREALDELRAE----LTLLNEE--AANLRERLESLERRIAATER 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   743 Q-RRLDYESQTahdnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHI 821
Cdd:TIGR02168  839 RlEDLEEQIEE-----LSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL 913

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530374448   822 SSKVEELSQALSQKELEITKMDQLLLEKKR----DVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLG 889
Cdd:TIGR02168  914 RRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELG 985
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 720-1451 7.85e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.09  E-value: 7.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   720 LSMVTELRAQVKQLEMNLAEAER-----QRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVlQNELDDVQLQFSEQS 794
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEeleklTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRV-KEKIGELEAEIASLE 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   795 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEisfsM 874
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE----T 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   875 TEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQnydemspagqiSKEELQHEFDLLKKENEQ 954
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA-----------KINELEEEKEDKALEIKK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   955 RKRKLQAALINRKELLQRVSRLEEELANLKDE---SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTIS 1031
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEYDRVEKElskLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGS 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1032 EKE-----VE------LQHIRKDLEEKLAAEEQFQALVK----------QMNQTLQDKT---------NQIDLL----QA 1077
Cdd:TIGR02169  533 VGEryataIEvaagnrLNNVVVEDDAVAKEAIELLKRRKagratflplnKMRDERRDLSilsedgvigFAVDLVefdpKY 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1078 EISENQAIIQKLITSNTDASD--GDSVALVK---ETVVISPPCTGSS------EHWKPELEEKILALEKEKEQLQKKLQE 1146
Cdd:TIGR02169  613 EPAFKYVFGDTLVVEDIEAARrlMGKYRMVTlegELFEKSGAMTGGSraprggILFSRSEPAELQRLRERLEGLKRELSS 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1147 ALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKlpsTDQQESCSSTPG 1226
Cdd:TIGR02169  693 LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK---SELKELEARIEE 769

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1227 LEEPLFKATEQhhtqpvlesnlcpdwpshSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQL 1306
Cdd:TIGR02169  770 LEEDLHKLEEA------------------LNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYL 831

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1307 QEqinkqglEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAA 1385
Cdd:TIGR02169  832 EK-------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQLRELERK 904

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448  1386 LTKIQTEIIEQEDLIKALHTQLEMQAkehdERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQA 1451
Cdd:TIGR02169  905 IEELEAQIEKKRKRLSELKAKLEALE----EELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 48-572 9.13e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 9.13e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEmkaqggtvlptepq 127
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL-------------- 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  128 sEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQpAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLS 207
Cdd:COG1196   301 -EQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL-EEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  208 QTQAEQAAQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEK 287
Cdd:COG1196   379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  288 MELEVAERKlsfhnLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNS 367
Cdd:COG1196   459 EALLELLAE-----LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  368 KLLQDKNEQA---------VQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQ 438
Cdd:COG1196   534 AAYEAALEAAlaaalqnivVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  439 KRVVELENEKGALLLSSIELEELK--AENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTF 516
Cdd:COG1196   614 RYYVLGDTLLGRTLVAARLEAALRraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL 693

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448  517 SQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAP 572
Cdd:COG1196   694 ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE 749
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1803-2303 1.06e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 64.70  E-value: 1.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1803 LQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLKETAEEE 1882
Cdd:PRK03918  230 VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKEL-KEKAEEYIKLSEFYEEYLDE 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1883 KDDLEERLMNQLAELNGsIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE------EEKQQLVKEKTKVESEIRKEYLE 1956
Cdd:PRK03918  309 LREIEKRLSRLEEEING-IEERIKELEEKEERLEELKKKLKELEKRLEELEerhelyEEAKAKKEELERLKKRLTGLTPE 387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1957 KIQGAQKEPGNKShaKELQELLKEKQQEVKQLQKDCIRYQEKISALER------------TVKALEFVQTESQKDLEITK 2024
Cdd:PRK03918  388 KLEKELEELEKAK--EEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIE 465

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2025 ENLAQAVEHRKKAQAELASFKVLLddtqsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN 2104
Cdd:PRK03918  466 KELKEIEEKERKLRKELRELEKVL-----KKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGE 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2105 MQ------EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQL----QENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKK 2174
Cdd:PRK03918  541 IKslkkelEKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2175 werkfsdaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHdkqiweskaqtevqlqqkvcdtlqgenkell 2254
Cdd:PRK03918  621 --------LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY------------------------------- 661

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*....
gi 530374448 2255 sqlEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLE 2303
Cdd:PRK03918  662 ---EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2184-2735 1.17e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2184 QSKEEEIRLKEDNCSVLKDQLRQMSIhmEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2263
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2264 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2343
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2344 KEQKIISLLSGKEEA-------------IQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLK 2410
Cdd:COG1196   370 AEAELAEAEEELEELaeellealraaaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2411 TIKK---ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSII-LEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2486
Cdd:COG1196   450 EEAEleeEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLeAEADYEGFLEGVKAALLLAGLRGLAGAVAVL 529

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2487 NSENAKLDAELIQYREDLNQVITIKDSQQ-KQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLS 2565
Cdd:COG1196   530 IGVEAAYEAALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2566 KEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLK 2645
Cdd:COG1196   610 EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2646 KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKY 2725
Cdd:COG1196   690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769

                         570
                  ....*....|
gi 530374448 2726 DASLKELAQL 2735
Cdd:COG1196   770 ERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 189-720 1.17e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.17e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  189 KQQLQEKEEFISTLQAQLSQTQA--EQAAQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAE 266
Cdd:COG1196   245 EAELEELEAELEELEAELAELEAelEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEE 324

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  267 HNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKhKAEMEEKTSHIL 346
Cdd:COG1196   325 LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA-LRAAAELAAQLE 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  347 SLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNrlpLQQHETASQTSFPDVYNEGT 426
Cdd:COG1196   404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA---LLELLAELLEEAALLEAALA 480

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  427 QAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQI-TLLEAQNRTGEADREVSEISIVDIANKRSSSAE 505
Cdd:COG1196   481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAA 560

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  506 ESGQDVLEN-----TFSQKHK-------ELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPI 573
Cdd:COG1196   561 AAIEYLKAAkagraTFLPLDKiraraalAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  574 KMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDgdkslsavpdigqchQDELERL 653
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA---------------LLAEEEE 705

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530374448  654 KSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL 720
Cdd:COG1196   706 ERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2015-2626 1.69e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 1.69e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2015 ESQKDLEITKENLAQA----VEHRK-----KAQAELAsfkvllddtqsEAARVLADNLKLKK-ELQSNKESVKSQMKQKD 2084
Cdd:COG1196   176 EAERKLEATEENLERLedilGELERqleplERQAEKA-----------ERYRELKEELKELEaELLLLKLRELEAELEEL 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2085 EDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAftksmssLQDD 2164
Cdd:COG1196   245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE-------LEER 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2165 RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2244
Cdd:COG1196   318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2245 TLQgENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLE 2324
Cdd:COG1196   398 LAA-QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2325 TDLQASRELTSRLHEEINMKEQkIISLLSGKEEAIQvAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQ 2404
Cdd:COG1196   477 AALAELLEELAEAAARLLLLLE-AEADYEGFLEGVK-AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE 554

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2405 LMETLKTIKKENIQQKAQLDSF-----VKSMSSLQNDRDRIVGDYQQLEERHLSIILE-KDQLIQEAAAENNKLKEEIRG 2478
Cdd:COG1196   555 DDEVAAAAIEYLKAAKAGRATFlpldkIRARAALAAALARGAIGAAVDLVASDLREADaRYYVLGDTLLGRTLVAARLEA 634

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2479 LRSHMDDLNSENAKLDAELIQyREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQ 2558
Cdd:COG1196   635 ALRRAVTLAGRLREVTLEGEG-GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAE 713

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530374448 2559 EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRlsalfSSSQKRIAELEEEL 2626
Cdd:COG1196   714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-----EELERELERLEREI 776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1797-2581 2.16e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.55  E-value: 2.16e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1797 DEINNYLQQIDQLKERIAGLEEEKQKN-KEFSQTLENEKNTLLSQISTKDGELKMLQEEVTK-----------MNLLNQQ 1864
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAKleaeidkllaeIEELERE 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1865 IQEELSRVTKLKETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKT 1944
Cdd:TIGR02169  345 IEEERKRRDKLTEEYAELKEELED-LRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA 423

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1945 KVESEIrkeylEKIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEItK 2024
Cdd:TIGR02169  424 DLNAAI-----AGIEAKINE--LEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE-A 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2025 ENLAQAVEHRkkaQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ----KDEDL---------ERRL 2091
Cdd:TIGR02169  496 EAQARASEER---VRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvvEDDAVakeaiellkRRKA 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2092 EQAEEKHLKEKKNMQEKLDALRREKVHleetigEIQVTLNKKDKEVQQ----------LQENLDSTVTQLAAFtkSMSSL 2161
Cdd:TIGR02169  573 GRATFLPLNKMRDERRDLSILSEDGVI------GFAVDLVEFDPKYEPafkyvfgdtlVVEDIEAARRLMGKY--RMVTL 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2162 QDD----RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDncsvLKDQLRQMSIHMEELKiNISRLEHDKQIWESKAQTEVQ 2237
Cdd:TIGR02169  645 EGElfekSGAMTGGSRAPRGGILFSRSEPAELQRLRER----LEGLKRELSSLQSELR-RIENRLDELSQELSDASRKIG 719

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2238 LQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEadIQNSK 2317
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSR--IPEIQ 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2318 FSYEQLETDLQASRELTSRLHEEINMKEQKiisllsgkeeaiqvaiaelRQQHDKEIKELENLLsqeeEENIVLEEENKK 2397
Cdd:TIGR02169  798 AELSKLEEEVSRIEARLREIEQKLNRLTLE-------------------KEYLEKEIQELQEQR----IDLKEQIKSIEK 854

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2398 AVDKTNQLMETLKTIKKENIQQKAQLDsfvKSMSSLQNDRDRIVGDYQQLEERhlsiilekdqlIQEAAAENNKLKEEIR 2477
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLE---SRLGDLKKERDELEAQLRELERK-----------IEELEAQIEKKRKRLS 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2478 GLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK-QLLEVQLQQNKELENKYAKLEeklkeseeanEDLRRSFNA 2556
Cdd:TIGR02169  921 ELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAElQRVEEEIRALEPVNMLAIQEY----------EEVLKRLDE 990

                          810       820
                   ....*....|....*....|....*
gi 530374448  2557 LQEEKQDLSKEIESLKVSISQLTRQ 2581
Cdd:TIGR02169  991 LKEKRAKLEEERKAILERIEEYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1591-2366 3.49e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 3.49e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1591 NEAERIQHVVEAVRQ-EKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHP 1669
Cdd:TIGR02169  208 EKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1670 AGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDnqtnv 1749
Cdd:TIGR02169  288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL----- 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1750 tEEGTQSIPGETEEQDSLSMSTRptcsesvpsaksanpavskdfsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1829
Cdd:TIGR02169  363 -KEELEDLRAELEEVDKEFAETR------------------------DELKDYREKLEKLKREINELKRELDRLQEELQR 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1830 LENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLmnqlaelngsignycqdvt 1909
Cdd:TIGR02169  418 LSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY------------------- 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1910 daqiknELLESEMKNLKKCVSELEEEKQQLVKEKT--KVESEIRKEYLEKIQGAQKEPG--NKSHAKELQELLKEKQQEV 1985
Cdd:TIGR02169  479 ------DRVEKELSKLQRELAEAEAQARASEERVRggRAVEEVLKASIQGVHGTVAQLGsvGERYATAIEVAAGNRLNNV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1986 ----KQLQKDCIRYQEKISALERTVKALEFVQTEsQKDLEITKEN-----LAQAVEHRKKAQaelASFKVLLDDT----Q 2052
Cdd:TIGR02169  553 vvedDAVAKEAIELLKRRKAGRATFLPLNKMRDE-RRDLSILSEDgvigfAVDLVEFDPKYE---PAFKYVFGDTlvveD 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2053 SEAARVLADNLKL--------------------KKELQSNKESVKSQMKQKDEDLErRLEQAEEKHLKEKKNMQEKLDAL 2112
Cdd:TIGR02169  629 IEAARRLMGKYRMvtlegelfeksgamtggsraPRGGILFSRSEPAELQRLRERLE-GLKRELSSLQSELRRIENRLDEL 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2113 RREKVHLEETIGEIQvtlnkkdKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKfsdaIQSKEEEIRL 2192
Cdd:TIGR02169  708 SQELSDASRKIGEIE-------KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR----IEELEEDLHK 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2193 KEDNCSVLKDQLRQMSI-----HMEELKINISRLE----HDKQIWESKAQTEVQLQQKVcDTLQGENKELLSQLEETRHL 2263
Cdd:TIGR02169  777 LEEALNDLEARLSHSRIpeiqaELSKLEEEVSRIEarlrEIEQKLNRLTLEKEYLEKEI-QELQEQRIDLKEQIKSIEKE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2264 YHSSQNELAKLESELKSLKDQLTDLSnslekckEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2343
Cdd:TIGR02169  856 IENLNGKKEELEEELEELEAALRDLE-------SRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA 928

                          810       820
                   ....*....|....*....|...
gi 530374448  2344 KEQKIISLLSGKEEAIQVAIAEL 2366
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEIPEEEL 951
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 519-1209 4.04e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.77  E-value: 4.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   519 KHKELSVLLLEMKEAQEEIAFLKLQLqgkraEEADHEVLDQKEMKQMEGEGIAPIKMKVFledtgqdfplmpneesslpa 598
Cdd:TIGR02168  223 RELELALLVLRLEELREELEELQEEL-----KEAEEELEELTAELQELEEKLEELRLEVS-------------------- 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   599 vEKEQASTEHQSR---TSEEISlndagvELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYE--- 672
Cdd:TIGR02168  278 -ELEEEIEELQKElyaLANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEelk 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   673 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEmnlaeaERQRRLDYESQ 751
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLE------DRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   752 TAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQ- 830
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGf 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   831 -----ALSQKELEITKMDQLLLEK-------KRDVET-----LQQTIEEKDQQVTEISFSMTEK-----------MVQLN 882
Cdd:TIGR02168  505 segvkALLKNQSGLSGILGVLSELisvdegyEAAIEAalggrLQAVVVENLNAAKKAIAFLKQNelgrvtflpldSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   883 EEKFSLGVEIKTLKEQLNLLSRAEEAKK----------------EQVEEDNEVSSGLKQNY-------DEMSPAGQISKE 939
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvlvvDDLDNALELAKKLRPGYrivtldgDLVRPGGVITGG 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   940 ELQHEFDLLK-----KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKC 1014
Cdd:TIGR02168  665 SAKTNSSILErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1015 VTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAE---EQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLit 1091
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL-- 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1092 SNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAI---LKKAQEKERHLREE 1168
Cdd:TIGR02168  823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLeeaLALLRSELEELSEE 902

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 530374448  1169 LKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESID 1209
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2134-2887 4.31e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 4.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2134 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERkfSDAIQSKEEEIRLKEdncsvLKDQLRQMSIHMEE 2213
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYE-----LLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2214 LKINISRLEhdkqiwESKAQTEVQLQQKVCDTlqGENKELLSQLEEtrHLYHSSQNELAKLESELKSLKDQLTDLSNSLE 2293
Cdd:TIGR02169  242 IERQLASLE------EELEKLTEEISELEKRL--EEIEQLLEELNK--KIKDLGEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2294 KCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSgKEEAIQVAIAELRQQHDKE 2373
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA-ELEEVDKEFAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2374 IKELENL-----------------LSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQND 2436
Cdd:TIGR02169  391 REKLEKLkreinelkreldrlqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2437 RDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENA---KLDAELIQYRED---------- 2503
Cdd:TIGR02169  471 LYDLKEEYDRVEKE----LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaag 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2504 --LNQVITIKDSQQKQLLEVqLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQ 2581
Cdd:TIGR02169  547 nrLNNVVVEDDAVAKEAIEL-LKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2582 VTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSqkRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNE 2661
Cdd:TIGR02169  626 VEDIEAARRLMGKYRMVTLEGELFEKSGAMTGGS--RAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2662 TETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKrkydaslKELAQLKEQglL 2741
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELE-------ARIEELEED--L 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2742 NRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRK 2821
Cdd:TIGR02169  775 HKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK 854

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2822 SEEG----KQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQE 2887
Cdd:TIGR02169  855 EIENlngkKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA 924
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1796-2509 8.57e-09

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 61.99  E-value: 8.57e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1796 HDEINNYLQQIDQL-KERIAGLEEEKQKNKEFSQTLENEKNTLLSQIS----TKDGELKMlQEEVTKMN----LLNQQIQ 1866
Cdd:TIGR01612 1050 HTSIYNIIDEIEKEiGKNIELLNKEILEEAEINITNFNEIKEKLKHYNfddfGKEENIKY-ADEINKIKddikNLDQKID 1128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1867 EELSRVTKLKETAEEEKDDLEERLmnqlaelngsigNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK------QQLV 1940
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKAQI------------NDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKniydeiKKLL 1196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1941 KEKTKVESEirKEYLEKIQGAqkepgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK-ISALERTVKALEFVQTESQKD 2019
Cdd:TIGR01612 1197 NEIAEIEKD--KTSLEEVKGI-----NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAyIEDLDEIKEKSPEIENEMGIE 1269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2020 LEITKENLAQAVEHRKKAQAELASFK--VLLDDTQSEAARVLADNLK------LKKELQSNKesvkSQMKQKDEDLERRL 2091
Cdd:TIGR01612 1270 MDIKAEMETFNISHDDDKDHHIISKKhdENISDIREKSLKIIEDFSEesdindIKKELQKNL----LDAQKHNSDINLYL 1345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2092 EQ-AEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDstvtqLAAFTKSMSSLQDDRDrvID 2170
Cdd:TIGR01612 1346 NEiANIYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDIN-----LEECKSKIESTLDDKD--ID 1418

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2171 EAKKWERKFSDAIQSKEEEI-----RLKEDNCSVLK-----DQLRQMSIHMEELKINISRLEHDKQIWESKAQTEvqlQQ 2240
Cdd:TIGR01612 1419 ECIKKIKELKNHILSEESNIdtyfkNADENNENVLLlfkniEMADNKSQHILKIKKDNATNDHDFNINELKEHID---KS 1495

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2241 KVCDTLQGENKEllsQLEETRHLYHSSQNELAKL-----ESELKSLKDQLTDLSNSL-EKCKEQKGNL---EGIIRQQEA 2311
Cdd:TIGR01612 1496 KGCKDEADKNAK---AIEKNKELFEQYKKDVTELlnkysALAIKNKFAKTKKDSEIIiKEIKDAHKKFileAEKSEQKIK 1572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2312 DIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISllsgkeeaiqvaIAELRQQHDKEIKELENLLSQEEE----E 2387
Cdd:TIGR01612 1573 EIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLK------------ISDIKKKINDCLKETESIEKKISSfsidS 1640

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2388 NIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQqleerhLSIIlekDQLIQEAAA 2467
Cdd:TIGR01612 1641 QDTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYE------IGII---EKIKEIAIA 1711

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 530374448  2468 ENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVIT 2509
Cdd:TIGR01612 1712 NKEEIESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNT 1753
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1806-2121 1.04e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 1.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1806 IDQLKERIAGLEEEKQKNKEFsQTLENEKNTL-----LSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE 1880
Cdd:COG1196   195 LGELERQLEPLERQAEKAERY-RELKEELKELeaellLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELR 273

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1881 EEKDDLEERLmnqlaelngsignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQG 1960
Cdd:COG1196   274 LELEELELEL------------------EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1961 AQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITK---ENLAQAVEHRKKA 2037
Cdd:COG1196   336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAaqlEELEEAEEALLER 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2038 QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKV 2117
Cdd:COG1196   416 LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLL 495


                  ....
gi 530374448 2118 HLEE 2121
Cdd:COG1196   496 LLEA 499
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2268-2737 1.30e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 60.80  E-value: 1.30e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2268 QNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE--EINMKE 2345
Cdd:TIGR04523  151 EKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISElkKQNNQL 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2346 QKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDS 2425
Cdd:TIGR04523  231 KDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNK 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2426 FVKSmsSLQNDRDRIVGDYQQLEERHLSIilekdqliqeaaaenNKLKEEIRGLRSHMDDLNSENAKLDAELiqyREDLN 2505
Cdd:TIGR04523  311 ELKS--ELKNQEKKLEEIQNQISQNNKII---------------SQLNEQISQLKKELTNSESENSEKQREL---EEKQN 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2506 QVITIKDSQQKQLlevqlQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2585
Cdd:TIGR04523  371 EIEKLKKENQSYK-----QEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2586 QEEGTlglyhaqlkVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETETA 2665
Cdd:TIGR04523  446 TNQDS---------VKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK-EKELKKLNEEKKELEEKVKDL 515

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530374448  2666 EERVAELARDLVEMEQKLLMVTKENKGLTAQIQS--FGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2737
Cdd:TIGR04523  516 TKKISSLKEKIEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQE 589
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1125-1616 1.75e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.75e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1125 ELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKerhlREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQV 1204
Cdd:PRK02224  217 ELDEEIERYEEQREQARETRDEA----DEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1205 ---RESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpDWPSHSEDASALQGgtSVAQIKAQLKEIEAE 1281
Cdd:PRK02224  289 eelEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRV--AAQAHNEEAESLRE--DADDLEERAEELREE 364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1282 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDE 1360
Cdd:PRK02224  365 AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTARERVEE 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1361 LQKL---------------------ISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALH--TQLEMQAKEHDER 1417
Cdd:PRK02224  445 AEALleagkcpecgqpvegsphvetIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDriERLEERREDLEEL 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1418 I---------KQLQVE-LCEMKQKPEEIGEESRAKQQIQR--------------KLQAALISRKEALKENKSLQEELSLA 1473
Cdd:PRK02224  525 IaerretieeKRERAEeLRERAAELEAEAEEKREAAAEAEeeaeeareevaelnSKLAELKERIESLERIRTLLAAIADA 604

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1474 RGTIERLTKSLADVeSQVSAQNKEkdtvlgRLALLQEERDKLITEMDRSLLEN-----QSLSSSCESLKLALEGLTEDKE 1548
Cdd:PRK02224  605 EDEIERLREKREAL-AELNDERRE------RLAEKRERKRELEAEFDEARIEEaredkERAEEYLEQVEEKLDELREERD 677

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530374448 1549 KLVKEIESLKSSkIAESTEWQEKHKELQKEYEILLQSYENVSneaeriqhvveavrqEKQELYGKLRS 1616
Cdd:PRK02224  678 DLQAEIGAVENE-LEELEELRERREALENRVEALEALYDEAE---------------ELESMYGDLRA 729
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 830-1727 1.92e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 60.76  E-value: 1.92e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   830 QALSQKELEITKMDQLL---LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKfslgVEIKTLKEQLNLLSRAE 906
Cdd:pfam02463  146 IIAMMKPERRLEIEEEAagsRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKE----QAKKALEYYQLKEKLEL 221

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   907 EAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE 986
Cdd:pfam02463  222 EEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   987 SKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTIS--EKEVELQHIRKDLEEKLAAEEQFQALVKQMNQT 1064
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKEleIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1065 LQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDsvalvketvvisppctgssEHWKPELEEKILALEKEKEQLQKKL 1144
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQL-------------------EDLLKEEKKEELEILEEEEESIELK 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1145 QEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSST 1224
Cdd:pfam02463  443 QGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGG 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1225 PGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVF 1304
Cdd:pfam02463  523 RIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1305 QLQEQINKQGLEIESLKTVSHEAEVHAESLQQK--LESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVS--YLSGQLS 1380
Cdd:pfam02463  603 LNLAQLDKATLEADEDDKRAKVVEGILKDTELTklKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKelLEIQELQ 682

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1381 EKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL 1460
Cdd:pfam02463  683 EKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEK 762

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1461 KENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTvlgrLALLQEERDKLITEMDRSLLENQSLSSSCESLKLAL 1540
Cdd:pfam02463  763 EEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE----LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEEL 838

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1541 EGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERiqhvvEAVRQEKQELYGKLRSTEAN 1620
Cdd:pfam02463  839 ALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEE-----KEKEEKKELEEESQKLNLLE 913

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1621 KKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHpaGDTAKECMETLLSSNASMKEELERVKMEYE 1700
Cdd:pfam02463  914 EKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEER--NKRLLLAKEELGKVNLMAIEEFEEKEERYN 991

                          890       900
                   ....*....|....*....|....*..
gi 530374448  1701 TLSKKFQSLMSEKDSLSEEVQDLKHQI 1727
Cdd:pfam02463  992 KDELEKERLEEEKKKLIRAIIEETCQR 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2177-2737 1.99e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.34  E-value: 1.99e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2177 RKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQiwesKAQTEVQLQQKvcdTLQGENKELLSQ 2256
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE----EAQAEEYELLA---ELARLEQDIARL 307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2257 LEETRHLyhssQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSR 2336
Cdd:COG1196   308 EERRREL----EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2337 LHEEINMKEQKIISLLSGKEEAIQV--AIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKK 2414
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEEAeeALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2415 ENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsiiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLD 2494
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLE------AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2495 AELIQYREDLNQVITIKDSQQ-KQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKV 2573
Cdd:COG1196   538 AALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2574 SISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHH 2653
Cdd:COG1196   618 LGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEE 697

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2654 DAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFG---------------------RSMSSLQNSRD 2712
Cdd:COG1196   698 ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEelleeealeelpeppdleeleRELERLEREIE 777

                         570       580       590
                  ....*....|....*....|....*....|..
gi 530374448 2713 H-------ANEELDELKRKYDASLKELAQLKE 2737
Cdd:COG1196   778 AlgpvnllAIEEYEELEERYDFLSEQREDLEE 809
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1793-2010 2.01e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 59.39  E-value: 2.01e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1793 FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEvtkMNLLNQQIQEELSRV 1872
Cdd:COG4942    16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE---LAALEAELAELEKEI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1873 TKLKETAEEEKDDLEERL-----MNQLAELNGSIGNycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVE 1947
Cdd:COG4942    93 AELRAELEAQKEELAELLralyrLGRQPPLALLLSP--EDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530374448 1948 SEiRKEYLEKIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALE 2010
Cdd:COG4942   171 AE-RAELEALLAELEEE------RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
PTZ00121 PTZ00121
MAEBL; Provisional
 1547-2346 2.34e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 2.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1547 KEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQE---LYGKLRSTEANKKE 1623
Cdd:PTZ00121 1153 RVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEearKAEDAKKAEAVKKA 1232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1624 TEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERV-------- 1695
Cdd:PTZ00121 1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKAdeakkkae 1312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1696 -KMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQanleatEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPT 1774
Cdd:PTZ00121 1313 eAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEA------EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK 1386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1775 cSESVPSAKSANPAVSKDFSSHDEINNYL---QQIDQLK---ERIAGLEEEKQKNKEFSQTLENEKNtllSQISTKDGEL 1848
Cdd:PTZ00121 1387 -AEEKKKADEAKKKAEEDKKKADELKKAAaakKKADEAKkkaEEKKKADEAKKKAEEAKKADEAKKK---AEEAKKAEEA 1462

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1849 KMLQEEVTKMNLLNQQiQEELSRVTKLKETAEEEKDDLEErlmnqlAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKC 1928
Cdd:PTZ00121 1463 KKKAEEAKKADEAKKK-AEEAKKADEAKKKAEEAKKKADE------AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK 1535

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1929 VSELEEEKQQLVKEKTKVESEIRK-EYLEKIQGAQKEpgnkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2007
Cdd:PTZ00121 1536 ADEAKKAEEKKKADELKKAEELKKaEEKKKAEEAKKA-------EEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK 1608

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2008 ALEFVQTESQKdleITKENLAQAVEHRKKaqAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK---ESVKSQMKQKD 2084
Cdd:PTZ00121 1609 AEEAKKAEEAK---IKAEELKKAEEEKKK--VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKaeeDKKKAEEAKKA 1683

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2085 EDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD---KEVQQLQENLDSTVTQLAAFTKSMSSL 2161
Cdd:PTZ00121 1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEeakKEAEEDKKKAEEAKKDEEEKKKIAHLK 1763

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2162 QDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNcsVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQK 2241
Cdd:PTZ00121 1764 KEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK--KIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNM 1841

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2242 VCDtlqgENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYE 2321
Cdd:PTZ00121 1842 QLE----EADAFEKHKFNKNNENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDD 1917

                         810       820
                  ....*....|....*....|....*
gi 530374448 2322 QLETDLQASRELTSRLHEEINMKEQ 2346
Cdd:PTZ00121 1918 KLDKDEYIKRDAEETREEIIKISKK 1942
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1379-1898 3.38e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 59.67  E-value: 3.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1379 LSEKEAALTKIQTEI--IEQEDLIKALHTqLEMQAKEHDERIKQLQVE---LCEMKQKPEEIGEESRAKQQIQRKLQAAL 1453
Cdd:PRK02224  182 LSDQRGSLDQLKAQIeeKEEKDLHERLNG-LESELAELDEEIERYEEQreqARETRDEADEVLEEHEERREELETLEAEI 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1454 ----ISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSL 1529
Cdd:PRK02224  261 edlrETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH 340

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1530 SSSCESLK---LALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQE 1606
Cdd:PRK02224  341 NEEAESLRedaDDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREE 420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1607 KQELYGKLRSTEANKKETEKQLQEAEQEMEE----------MKEKMRKFAKSKQQKILELEEENDRLRAEVhpagdtake 1676
Cdd:PRK02224  421 RDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEV--------- 491

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1677 cmetllssnASMKEELERVKMEYETlSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANL-EATEKHDNQTNVTEEGTQ 1755
Cdd:PRK02224  492 ---------EEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRETIEEKRERAEELrERAAELEAEAEEKREAAA 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1756 SIPGETEEqdslSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKN 1835
Cdd:PRK02224  562 EAEEEAEE----AREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKR 637

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448 1836 TLLSQIStkDGELKMLQEEvtkmnllNQQIQEELSRVTKLKETAEEEKDDLEER---LMNQLAELN 1898
Cdd:PRK02224  638 ELEAEFD--EARIEEARED-------KERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELE 694
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1125-1666 4.12e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 4.12e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1125 ELEEKILALEKEKEQLQK--KLQEALTSRKAILKKAqeKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQI 1202
Cdd:COG1196   197 ELERQLEPLERQAEKAERyrELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRL 274

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1203 QVRESIDgklpstdqqescsstpgleeplfkateqhhtqpvlesnlcpdwpshsedasalqggtSVAQIKAQLKEIEAEK 1282
Cdd:COG1196   275 ELEELEL---------------------------------------------------------ELEEAQAEEYELLAEL 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1283 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHlrelqpKLDELQ 1362
Cdd:COG1196   298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEE------ALLEAE 371

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1363 KLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAK 1442
Cdd:COG1196   372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEE 451

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1443 QQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRS 1522
Cdd:COG1196   452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIG 531

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1523 LLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS-----------SKIAESTEWQEKHKELQKEYEILLQSYENVSN 1591
Cdd:COG1196   532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflplDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530374448 1592 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1666
Cdd:COG1196   612 DARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAE 686
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
190-343 4.24e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 4.24e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  190 QQLQEKEEFISTLQAQLSQTQAEQAAQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQ-----RNQILS---QQLQ 261
Cdd:COG4913   262 ERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREeldelEAQIRGnggDRLE 341

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  262 QMEAEHNTL---RNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQ----AGQAQAELESRYSALEQKH 334
Cdd:COG4913   342 QLEREIERLereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEeleaLEEALAEAEAALRDLRREL 421


                  ....*....
gi 530374448  335 KAEMEEKTS 343
Cdd:COG4913   422 RELEAEIAS 430
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1265-2143 5.41e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.21  E-value: 5.41e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1265 GTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1344
Cdd:pfam02463  161 EAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1345 IagLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1424
Cdd:pfam02463  241 L--LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1425 LCEMKQKpeeigeesrakqqIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1504
Cdd:pfam02463  319 SEKEKKK-------------AEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1505 LALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQ 1584
Cdd:pfam02463  386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1585 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLR 1664
Cdd:pfam02463  466 ELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1665 AEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHD 1744
Cdd:pfam02463  546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1745 NQTNVTEEGTQSIPGETEEQDSLSMstrptcsesVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1824
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRK---------GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILR 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1825 EFSQTLENEKNTLLSQISTKDGELKMLQEEVT-KMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGN 1903
Cdd:pfam02463  697 RQLEIKKKEQREKEELKKLKLEAEELLADRVQeAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKEL 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1904 YCQDVTDAQIKNElLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepgnKSHAKELQELLKEKQQ 1983
Cdd:pfam02463  777 AEEREKTEKLKVE-EEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIK--------EEELEELALELKEEQK 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1984 EVKQLQKDCIRYQEKISALERTVKALEfvqtESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNL 2063
Cdd:pfam02463  848 LEKLAEEELERLEEEITKEELLQELLL----KEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERI 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2064 KLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN 2143
Cdd:pfam02463  924 KEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1023-1888 6.52e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 6.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1023 EIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDAsDGDSV 1102
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL-QKELY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1103 ALVKEtvvisppctgssehwKPELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQ 1182
Cdd:TIGR02168  292 ALANE---------------ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELAEELAELEEKLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1183 FDEQSKENENIGDQLRQLQIQVREsidgklpstDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpSHSEDasal 1262
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEE---------LEEQLETLRSKVAQLELQIASLNNEIERLEARL-----ERLED---- 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1263 qggtSVAQIKAQLKEIEAEKVELELKVSSTtsELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQ 1342
Cdd:TIGR02168  415 ----RRERLQQEIEELLKKLEEAELKELQA--ELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1343 LQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEK-------EAALtkiqtEIIEQEDLIKALHTQLE--MQAKE 1413
Cdd:TIGR02168  489 ARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAI-----EAALGGRLQAVVVENLNaaKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1414 HDERIKQLQVELCEMKQKPEeigeesrakQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSA 1493
Cdd:TIGR02168  564 FLKQNELGRVTFLPLDSIKG---------TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNA 634

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1494 QNKEK-------------DTVLGRLALLQ--EERDKLITEMDRSLLENQS----LSSSCESLKLALEGLTEDKEKLVKEI 1554
Cdd:TIGR02168  635 LELAKklrpgyrivtldgDLVRPGGVITGgsAKTNSSILERRREIEELEEkieeLEEKIAELEKALAELRKELEELEEEL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1555 ESLKSSKIAESTewqeKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEkqlqeaeQE 1634
Cdd:TIGR02168  715 EQLRKELEELSR----QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE-------AE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1635 MEEMKEKMRKFAKSKQQKILELEEENDRLRAevhpagdtakecmetLLSSNASMKEELERVKMEYETLSKKFQSLMSEKD 1714
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTL---------------LNEEAANLRERLESLERRIAATERRLEDLEEQIE 848

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1715 SLSEEVQDLKHQIEGNVSKQANLE-ATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKdf 1793
Cdd:TIGR02168  849 ELSEDIESLAAEIEELEELIEELEsELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ-- 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1794 sSHDEINNYLQQIDQLKERIAgleEEKQKNKEFSQTLENEKNTLLSQIstkDGELKMLQEEVTKMNLLNQQIQEELSRVT 1873
Cdd:TIGR02168  927 -LELRLEGLEVRIDNLQERLS---EEYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIKELGPVNLAAIEEYEELK 999

                          890
                   ....*....|....*
gi 530374448  1874 KLKETAEEEKDDLEE 1888
Cdd:TIGR02168 1000 ERYDFLTAQKEDLTE 1014
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1397-2142 8.35e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 58.59  E-value: 8.35e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1397 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1473
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKfylRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1474 RGT-IERLTKSLADVESQVSAqnkekdtVLGRLALLQEERDKLITEMDR-SLLENQSLSSSCESLKLALEgltedkeklv 1551
Cdd:pfam15921  168 SNTqIEQLRKMMLSHEGVLQE-------IRSILVDFEEASGKKIYEHDSmSTMHFRSLGSAISKILRELD---------- 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1552 KEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYEnvsneaERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1631
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEII 304

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1632 EQEMEEMKEKMrkfakskQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLms 1711
Cdd:pfam15921  305 QEQARNQNSMY-------MRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNL-- 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1712 eKDSLSEEVQDL-KHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVS 1790
Cdd:pfam15921  376 -DDQLQKLLADLhKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1791 KDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKM----NLLNQQIQ 1866
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLrsrvDLKLQELQ 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1867 EELSRVTKLKETAEE---------EKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQ 1937
Cdd:pfam15921  535 HLKNEGDHLRNVQTEcealklqmaEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKD 614

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1938 QLVKEKTKVESEIRKEYLEKIQ----GAQKEPGNKSHAKELQELLKE---KQQEVKQLQKDC----IRYQEKISALERTV 2006
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKlvnaGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTT 694

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2007 KALEFVQTESQKDLEITKENL-------AQAVEHRKKAQAELASFKVLLDDTQSEaarvladnLKLKKELQSNKESVKSQ 2079
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLksmegsdGHAMKVAMGMQKQITAKRGQIDALQSK--------IQFLEEAMTNANKEKHF 766

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530374448  2080 MKQKDEDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQE 2142
Cdd:pfam15921  767 LKEEKNKLSQELSTVA----TEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2602-2905 8.87e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 8.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2602 EEEVHRLSALFSSSQKRIAELEEelvcvQKEAAKKVGEIEDKLKK--------ELKHLHHDAGIMRNETETAEERVAELA 2673
Cdd:COG1196   185 EENLERLEDILGELERQLEPLER-----QAEKAERYRELKEELKEleaellllKLRELEAELEELEAELEELEAELEELE 259

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2674 RDLVEME-------QKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERD 2746
Cdd:COG1196   260 AELAELEaeleelrLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEEL 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2747 ALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR----KS 2822
Cdd:COG1196   340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLerleRL 419

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2823 EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEEL 2902
Cdd:COG1196   420 EEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEA 499


                  ...
gi 530374448 2903 RQE 2905
Cdd:COG1196   500 EAD 502
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 510-1400 1.45e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.76  E-value: 1.45e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   510 DVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQkemkqmegegiapikmkvfledtgqdfplm 589
Cdd:TIGR02168  228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVS------------------------------ 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   590 pneesslpavEKEQASTEHQSR---TSEEISlndagvELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHK 666
Cdd:TIGR02168  278 ----------ELEEEIEELQKElyaLANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   667 AQEIYE---KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEmnlaeaER 742
Cdd:TIGR02168  342 LEEKLEelkEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnNEIERLEARLERLE------DR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   743 QRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHIS 822
Cdd:TIGR02168  416 RERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE 495

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   823 SKVEELSQalsqkeleITKMDQLLLEKKRDVETLQQTIEEKdqqvteISFsmtekmvqlnEEKFSLGVEIkTLKEQLN-L 901
Cdd:TIGR02168  496 RLQENLEG--------FSEGVKALLKNQSGLSGILGVLSEL------ISV----------DEGYEAAIEA-ALGGRLQaV 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   902 LSRAEEAKKEQVEEDNEVSSG------LKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSR 975
Cdd:TIGR02168  551 VVENLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDD 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   976 LEEELANLKDESKKEIPLSE-----TERGEVEEDKENKEYSekcVTSKCQEIEIyLKQTISEKEVELQHIRKDLEEKLAA 1050
Cdd:TIGR02168  631 LDNALELAKKLRPGYRIVTLdgdlvRPGGVITGGSAKTNSS---ILERRREIEE-LEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1051 EEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVisppctgssEHWKPELEEKI 1130
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL---------EERLEEAEEEL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1131 LALEKEKEQLQ---KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1207
Cdd:TIGR02168  778 AEAEAEIEELEaqiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES- 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1208 idgklpSTDQQEScsstpgLEEPLFKATEQHHtqpvlesnlcpdwpSHSEDASALQggTSVAQIKAQLKEIEAEKVELEL 1287
Cdd:TIGR02168  857 ------LAAEIEE------LEELIEELESELE--------------ALLNERASLE--EALALLRSELEELSEELRELES 908

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1288 KVSSTTSELTKKSEEVFQLQEQINKQGLEIESLK-TVSHEAEVHAESLQQKLESSQLQIAGLE-HLRELQPKLDELQKL- 1364
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIDNLQeRLSEEYSLTLEEAEALENKIEDDEEEARrRLKRLENKIKELGPVn 988

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|..
gi 530374448  1365 ------ISKKEEDVSYLSGQLSEKEAALTKIQtEIIEQEDLI 1400
Cdd:TIGR02168  989 laaieeYEELKERYDFLTAQKEDLTEAKETLE-EAIEEIDRE 1029
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 647-1185 1.62e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 1.62e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  647 QDELERLKSQILELELNFHKAQE---IYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SM 722
Cdd:COG1196   266 EAELEELRLELEELELELEEAQAeeyELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELeEE 345

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  723 VTELRAQVKQLEMNLAEAERQRRLDYESQTAHDnlltEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 802
Cdd:COG1196   346 LEEAEEELEEAEAELAEAEEALLEAEAELAEAE----EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEE 421

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  803 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM-TEKMVQL 881
Cdd:COG1196   422 ELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLlLLLEAEA 501

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  882 NEEKFSLGVEIKTLKEQLNLLSRA------EEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISkeelqhefDLLKKENEQR 955
Cdd:COG1196   502 DYEGFLEGVKAALLLAGLRGLAGAvavligVEAAYEAALEAALAAALQNIVVEDDEVAAAAI--------EYLKAAKAGR 573

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  956 KRKLQAALINRKELLQRVSRLEEEL-------ANLKDESKKEIPLSETERGE--VEEDKENKEYSEKCVTSKCQEIEIYL 1026
Cdd:COG1196   574 ATFLPLDKIRARAALAAALARGAIGaavdlvaSDLREADARYYVLGDTLLGRtlVAARLEAALRRAVTLAGRLREVTLEG 653

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1027 KQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVK 1106
Cdd:COG1196   654 EGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1107 ETvvisppctgssehwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLR----------EELKQQKDDY 1176
Cdd:COG1196   734 RE----------------ELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEalgpvnllaiEEYEELEERY 797


                  ....*....
gi 530374448 1177 NRLQEQFDE 1185
Cdd:COG1196   798 DFLSEQRED 806
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1351-1567 1.68e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 1.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1351 LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1430
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1431 KPEEIGEESRAKQQIQRKLQAALI----SRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLA 1506
Cdd:COG4942   102 QKEELAELLRALYRLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530374448 1507 LLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE 1567
Cdd:COG4942   182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1279-1942 2.30e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 56.95  E-value: 2.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1279 EAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGL-EHLRELQPK 1357
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1358 LDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEhderIKQLQVELCEMKQKPEEIGE 1437
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQ----KEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1438 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLIT 1517
Cdd:TIGR04523  188 NIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1518 EMDRSLLEnqslsssCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTewQEKHKELQKEYEILLQSYENVSNEAERIQ 1597
Cdd:TIGR04523  268 QLSEKQKE-------LEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWN--KELKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1598 HVVEAVRQEKQELYGKLRSTEANKKETEKqlqeaeqemeemkekmrkfaksKQQKILELEEENDRLraevhpagdtaKEC 1677
Cdd:TIGR04523  339 QLNEQISQLKKELTNSESENSEKQRELEE----------------------KQNEIEKLKKENQSY-----------KQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1678 METLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLeatEKHDNQTNVTEEGTQSI 1757
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL---TNQDSVKELIIKNLDNT 462

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1758 PGETEEQDSlsmstrpTCSESVPSAKSANPAVSKDFSSH-DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNT 1836
Cdd:TIGR04523  463 RESLETQLK-------VLSRSINKIKQNLEQKQKELKSKeKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKE 535

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1837 LLSQISTKDGELKMLQEEVTKMNL------LNQQIQEELSRVTKLKETAEEEKDDLEER------LMNQLAELNGSIGNY 1904
Cdd:TIGR04523  536 KESKISDLEDELNKDDFELKKENLekeideKNKEIEELKQTQKSLKKKQEEKQELIDQKekekkdLIKEIEEKEKKISSL 615

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 530374448  1905 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKE 1942
Cdd:TIGR04523  616 EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653
PTZ00121 PTZ00121
MAEBL; Provisional
 1269-1825 2.56e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1269 AQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTvsHEAEVHAESLQQKLESSQLQIAGL 1348
Cdd:PTZ00121 1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK--EEAKKKADAAKKKAEEKKKADEAK 1397

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1349 EHLRELQPKLDELQKLIS--KKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelc 1426
Cdd:PTZ00121 1398 KKAEEDKKKADELKKAAAakKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD---- 1473

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1427 EMKQKPEEI--GEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGR 1504
Cdd:PTZ00121 1474 EAKKKAEEAkkADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1505 LALLQEERDKLITEMDRSLLENQSLSS-SCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILL 1583
Cdd:PTZ00121 1554 AEELKKAEEKKKAEEAKKAEEDKNMALrKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKK 1633

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1584 QSYENVSNEAERIQHvVEAVRQEKQELYGKlRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL 1663
Cdd:PTZ00121 1634 KVEQLKKKEAEEKKK-AEELKKAEEENKIK-AAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKE 1711

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1664 RAEVHPAGDTAKECMETLL-SSNASMKEELERVKMEY----ETLSKKFQSLMSEKDSLSEEVQDLKHQI------EGNVS 1732
Cdd:PTZ00121 1712 AEEKKKAEELKKAEEENKIkAEEAKKEAEEDKKKAEEakkdEEEKKKIAHLKKEEEKKAEEIRKEKEAVieeeldEEDEK 1791

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1733 KQANLEATEK--HDNQTNVTEEGTQSIP----------GETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEIN 1800
Cdd:PTZ00121 1792 RRMEVDKKIKdiFDNFANIIEGGKEGNLvindskemedSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEADFN 1871

                         570       580
                  ....*....|....*....|....*
gi 530374448 1801 NYLQQIDQLKERIAGLEEEKQKNKE 1825
Cdd:PTZ00121 1872 KEKDLKEDDEEEIEEADEIEKIDKD 1896
PTZ00121 PTZ00121
MAEBL; Provisional
 666-1193 3.27e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 3.27e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  666 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQ 743
Cdd:PTZ00121 1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  744 RRLDYESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 816
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  817 RVRHISSKVEELSQA--LSQKELEITKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 892
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  893 KTLKEqlnlLSRAEEAKKEQVEEDNEVssglKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 972
Cdd:PTZ00121 1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  973 VSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE 1052
Cdd:PTZ00121 1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1053 QFQAlvKQMNQTLQDKTNQIDLLQAEISENQaiiqklitsntdasdgdsvalvketvvisppctgssehwKPELEEKILA 1132
Cdd:PTZ00121 1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530374448 1133 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1193
Cdd:PTZ00121 1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 953-1557 5.83e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 5.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  953 EQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEiplsETERGEVEEDKENkeysekcvtskcqeieiyLKQTISE 1032
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEEL----EAELAELEAELEE------------------LRLELEE 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1033 KEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSntdasdgdsvalvketvvis 1112
Cdd:COG1196   279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEE-------------------- 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1113 ppctgssehwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQ----------KDDYNRLQEQ 1182
Cdd:COG1196   339 ----------LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELlealraaaelAAQLEELEEA 408

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1183 FDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsEDASAL 1262
Cdd:COG1196   409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL--------LEAALA 480

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1263 QGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKK-----SEEVFQLQEQINKQGLEIE-----SLKTVSHEAEVHAE 1332
Cdd:COG1196   481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAglrglAGAVAVLIGVEAAYEAALEaalaaALQNIVVEDDEVAA 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1333 SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAK 1412
Cdd:COG1196   561 AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1413 EHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVS 1492
Cdd:COG1196   641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530374448 1493 AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQslssscESLKLALEGLTEDKEKLVKEIESL 1557
Cdd:COG1196   721 LEEEALEEQLEAEREELLEELLEEEELLEEEALEE------LPEPPDLEELERELERLEREIEAL 779
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1544-2121 5.95e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.46  E-value: 5.95e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1544 TEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIqhvvEAVRQEKQELYGKLRSTEANKKE 1623
Cdd:PRK03918  188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI----EELEKELESLEGSKRKLEEKIRE 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1624 TEKQLQEAEQEMEEMKEKM----------------RKFAKSKQQKILELEEENDRLRAEVhpagdtakECMETLLSSNAS 1687
Cdd:PRK03918  264 LEERIEELKKEIEELEEKVkelkelkekaeeyiklSEFYEEYLDELREIEKRLSRLEEEI--------NGIEERIKELEE 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1688 MKEELERVKMEYETLSKKFQSLmSEKDSLSEEVQDLKHQIEGNVSKQANL---EATEKHDNQTNVTEEGTQSIPGETEEQ 1764
Cdd:PRK03918  336 KEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELERLKKRLTGLtpeKLEKELEELEKAKEEIEEEISKITARI 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1765 DSLS--MSTRPTCSESVPSAKSANPAVSKDFSSHDE---INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKN---T 1836
Cdd:PRK03918  415 GELKkeIKELKKAIEELKKAKGKCPVCGRELTEEHRkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKkesE 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1837 LLSQISTKDgELKMLQEEVTKMNLlnqqiqEELSRVTKLKETAEEEKDDLEERLMNQLAELNgsignycqdvtdaqiKNE 1916
Cdd:PRK03918  495 LIKLKELAE-QLKELEEKLKKYNL------EELEKKAEEYEKLKEKLIKLKGEIKSLKKELE---------------KLE 552

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1917 LLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIqgaqkepgnkshaKELQELLKEkQQEVKQLQKDCIRYQ 1996
Cdd:PRK03918  553 ELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL-------------KELEPFYNE-YLELKDAEKELEREE 618

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1997 EKISALERTVKALEFVQTESQKDLEITKENLAQAveHRKKAQAELASFKVLLDDTQSEAARVLADnlklKKELQSNKESV 2076
Cdd:PRK03918  619 KELKKLEEELDKAFEELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAE----LEELEKRREEI 692

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*..
gi 530374448 2077 KSQMKQKDEDLERRLEQAEEKHLKEK--KNMQEKLDALRREKVHLEE 2121
Cdd:PRK03918  693 KKTLEKLKEELEEREKAKKELEKLEKalERVEELREKVKKYKALLKE 739
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1911-2652 8.43e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 8.43e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1911 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 1990
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1991 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2070
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2071 SNKESVKSQMKQKDEdlerrLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEnldstvtq 2150
Cdd:pfam02463  332 KEKEEIEELEKELKE-----LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELE-------- 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2151 LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWES 2230
Cdd:pfam02463  399 LKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2231 KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQE 2310
Cdd:pfam02463  479 LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2311 ADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIV 2390
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2391 LEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRivgdyQQLEERHLSIILEKDQLIQEAAAENN 2470
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAES-----ELAKEEILRRQLEIKKKEQREKEELK 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2471 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDL 2550
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKE 793

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2551 RRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEvhrLSALFSSSQKRIAELEEELVCVQ 2630
Cdd:pfam02463  794 EKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQK---LEKLAEEELERLEEEITKEELLQ 870

                          730       740
                   ....*....|....*....|..
gi 530374448  2631 KEAAKKVGEIEDKLKKELKHLH 2652
Cdd:pfam02463  871 ELLLKEEELEEQKLKDELESKE 892
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 286-1101 8.51e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.06  E-value: 8.51e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   286 EKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHkaemEEKTSHILSLQKTGQELQSACDALKdq 365
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL----EELRLEVSELEEEIEELQKELYALA-- 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   366 nsKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQtsfpdvynEGTQAVTEENIASLQKRVVELE 445
Cdd:TIGR02168  295 --NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL--------EEKLEELKEELESLEAELEELE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   446 NEKGALLLSSIELEElkaENEKLSSQITLLEAQNRTGEADREVSEISIVDIA---NKRSSSAEESGQDVLENTFSQKHKE 522
Cdd:TIGR02168  365 AELEELESRLEELEE---QLETLRSKVAQLELQIASLNNEIERLEARLERLEdrrERLQQEIEELLKKLEEAELKELQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   523 LSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEgEGIAPIKMKVFLEDTGQDFPlmpneESSLPAVEKE 602
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA-QLQARLDSLERLQENLEGFS-----EGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   603 QASTEHQSRTSEEISLnDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKsqilelELNFHKAQEIYEKNLDEKAKEI 682
Cdd:TIGR02168  516 SGLSGILGVLSELISV-DEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLK------QNELGRVTFLPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   683 SNLNQL--IEEFKKNADNNSSAFTALSEERDQLLSQVKelsMVTelraqvkqlemNLAEAERQRRLDYESQtahdNLLTE 760
Cdd:TIGR02168  589 NDREILknIEGFLGVAKDLVKFDPKLRKALSYLLGGVL---VVD-----------DLDNALELAKKLRPGY----RIVTL 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   761 QIHSLSIE------AKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVlegaervrhisskvEELSQALSQ 834
Cdd:TIGR02168  651 DGDLVRPGgvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL--------------EELEEELEQ 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   835 KELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQlnllsraeEAKKEQVE 914
Cdd:TIGR02168  717 LRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEA--------EAEIEELE 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   915 EDNEVSSGLKQNYDEMSpagqiskEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLkdesKKEIPLS 994
Cdd:TIGR02168  789 AQIEQLKEELKALREAL-------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL----SEDIESL 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   995 ETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQAL---VKQMNQTLQDKTNQ 1071
Cdd:TIGR02168  858 AAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELrekLAQLELRLEGLEVR 937

                          810       820       830
                   ....*....|....*....|....*....|
gi 530374448  1072 IDLLQAEISENQAIIQKLITSNTDASDGDS 1101
Cdd:TIGR02168  938 IDNLQERLSEEYSLTLEEAEALENKIEDDE 967
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1270-2117 1.12e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.67  E-value: 1.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1270 QIKAQLKEIEAEKvELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLES----SQLQI 1345
Cdd:TIGR00606  225 QITSKEAQLESSR-EIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1346 AGLEH-----LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTK-------IQTEIIEQEDLIKALHTQLEMQAKE 1413
Cdd:TIGR00606  304 NDLYHnhqrtVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRlqlqadrHQEHIRARDSLIQSLATRLELDGFE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1414 HDERIKQLQVELCEMKQKPEEigEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLARGTIERLTKSLADVESQvsa 1493
Cdd:TIGR00606  384 RGPFSERQIKNFHTLVIERQE--DEAKTAAQLCADLQSKERLKQEQADE---IRDEKKGLGRTIELKKEILEKKQEE--- 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1494 qnkekdtvlgrLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALE-GLTEDKEKLVKEIESLKSSKIAESTEWQEKH 1572
Cdd:TIGR00606  456 -----------LKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKnSLTETLKKEVKSLQNEKADLDRKLRKLDQEM 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1573 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLrSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQk 1652
Cdd:TIGR00606  525 EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLL-GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELAS- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1653 ileLEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEE--LERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGN 1730
Cdd:TIGR00606  603 ---LEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEEsdLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSC 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1731 VSKQANLEATEKHDNQ-TNVTEEGTQSIPGETEEQDSLSMSTRptcsesvpsaKSANPAVSKDFSSHDEINNYLQQIDQL 1809
Cdd:TIGR00606  680 CPVCQRVFQTEAELQEfISDLQSKLRLAPDKLKSTESELKKKE----------KRRDEMLGLAPGRQSIIDLKEKEIPEL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1810 KERIAGLEEEKQKNKEFSQtlenEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAE--------- 1880
Cdd:TIGR00606  750 RNKLQKVNRDIQRLKNDIE----EQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQgsdldrtvq 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1881 ------EEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1954
Cdd:TIGR00606  826 qvnqekQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIK 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1955 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKEN-------- 2026
Cdd:TIGR00606  906 DAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETelntvnaq 985

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2027 LAQAVEHRKKAQAELASFKVLLdDTQSEAARVLADNLKLKK---ELQSNKESVKSQMKQKDEDLERRLEQAEEKhlkekk 2103
Cdd:TIGR00606  986 LEECEKHQEKINEDMRLMRQDI-DTQKIQERWLQDNLTLRKrenELKEVEEELKQHLKEMGQMQVLQMKQEHQK------ 1058

                          890
                   ....*....|....
gi 530374448  2104 nMQEKLDALRREKV 2117
Cdd:TIGR00606 1059 -LEENIDLIKRNHV 1071
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1380-2873 1.16e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 55.06  E-value: 1.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1380 SEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIGEE----SRAKQQIQRKLQAaLIS 1455
Cdd:TIGR01612  540 KEIEAGLKESYELAKNWKKLIHEIKKELE----EENEDSIHLEKEIKDLFDKYLEIDDEiiyiNKLKLELKEKIKN-ISD 614

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1456 RKEALKENKSLQEELSLARGTIERLTK-SLADVESQVSAQNKEKDTVLGRLA-LLQEERDKLITEMDRSLLENQSLSssc 1533
Cdd:TIGR01612  615 KNEYIKKAIDLKKIIENNNAYIDELAKiSPYQVPEHLKNKDKIYSTIKSELSkIYEDDIDALYNELSSIVKENAIDN--- 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1534 eslklaleglTEDKEKLvkeiESLKSSKIAESTEWQEKHKELQKEYeilLQSYENVSNEAERIqhVVEAVRQEKQELYGK 1613
Cdd:TIGR01612  692 ----------TEDKAKL----DDLKSKIDKEYDKIQNMETATVELH---LSNIENKKNELLDI--IVEIKKHIHGEINKD 752

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1614 LRSTEANKKETEKQLQEAEQEMEEMKEKMRKFakskQQKILELEEE-NDRLR------AEVHPAGDTAKECMETLLSSNA 1686
Cdd:TIGR01612  753 LNKILEDFKNKEKELSNKINDYAKEKDELNKY----KSKISEIKNHyNDQINidnikdEDAKQNYDKSKEYIKTISIKED 828

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1687 SMKEELERVK-MEYETLSK-----KFQSLMSEK-DSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIpg 1759
Cdd:TIGR01612  829 EIFKIINEMKfMKDDFLNKvdkfiNFENNCKEKiDSEHEQFAELTNKIKAEISDDKLNDYEKKFNDSKSLINEINKSI-- 906

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1760 eteEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQ-IDQLKEriAGLEEEKQKNKeFSQTLENEKNTL- 1837
Cdd:TIGR01612  907 ---EEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEILNKnIDTIKE--SNLIEKSYKDK-FDNTLIDKINELd 980

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1838 -------LSQISTKDGEL----KMLQEEV--TKMNLLNQQIQEELSRVTKLketaEEEKDDLEERLMNQLAELNGSIGNY 1904
Cdd:TIGR01612  981 kafkdasLNDYEAKNNELikyfNDLKANLgkNKENMLYHQFDEKEKATNDI----EQKIEDANKNIPNIEIAIHTSIYNI 1056

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1905 CQDVTDAQIKN-ELLESE-MKNLKKCVSELEEEKQQL----VKEKTKVESEIRKEYLEKIQGAQKEPGNK--SHAKELQE 1976
Cdd:TIGR01612 1057 IDEIEKEIGKNiELLNKEiLEEAEINITNFNEIKEKLkhynFDDFGKEENIKYADEINKIKDDIKNLDQKidHHIKALEE 1136

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1977 LLKEKQQEVKQLQKdciryqeKISALERTvkALEFVQTESQKDLEITKENLAQAVEHRKKAQAELasfKVLLddtqSEAA 2056
Cdd:TIGR01612 1137 IKKKSENYIDEIKA-------QINDLEDV--ADKAISNDDPEEIEKKIENIVTKIDKKKNIYDEI---KKLL----NEIA 1200

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2057 RVLADNLKLKK----ELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV-- 2128
Cdd:TIGR01612 1201 EIEKDKTSLEEvkgiNLSYGKNLGKLFLEKIDEEKKKseHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMETfn 1280

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2129 TLNKKDKEVQQLQENLDSTVTQLAafTKSMSSLQDD-RDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLkdqlrqm 2207
Cdd:TIGR01612 1281 ISHDDDKDHHIISKKHDENISDIR--EKSLKIIEDFsEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANI------- 1351

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2208 sihmeelkINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyhSSQNELAKLESELKSLKDQLtd 2287
Cdd:TIGR01612 1352 --------YNILKLNKIKKIID-------------------EVKEYTKEIEENNK---NIKDELDKSEKLIKKIKDDI-- 1399

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2288 lsnSLEKCKEQkgnLEGIIRQQEAD--IQNSKFSYEQL---ETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVA 2362
Cdd:TIGR01612 1400 ---NLEECKSK---IESTLDDKDIDecIKKIKELKNHIlseESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIK 1473

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2363 IAELRQQHDKEIKELENLLSQEEEENIVLEEeNKKAVDKTNQLMETLKTIKKENIQQKAQLdSFVKSMSSLQNDRDRIVg 2442
Cdd:TIGR01612 1474 KDNATNDHDFNINELKEHIDKSKGCKDEADK-NAKAIEKNKELFEQYKKDVTELLNKYSAL-AIKNKFAKTKKDSEIII- 1550

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2443 dyQQLEERHLSIILE------------KDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDaeliQYREDLNQVIT 2509
Cdd:TIGR01612 1551 --KEIKDAHKKFILEaekseqkikeikKEKFrIEDDAAKNDKSNKAAIDIQLSLENFENKFLKIS----DIKKKINDCLK 1624

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2510 IKDSQQKQL--LEVQLQQNKELENKYAKLEEKLKESEEANEdlRRSFNALQEEKQDLSKEIESLKVSISQLTRQVtalqE 2587
Cdd:TIGR01612 1625 ETESIEKKIssFSIDSQDTELKENGDNLNSLQEFLESLKDQ--KKNIEDKKKELDELDSEIEKIEIDVDQHKKNY----E 1698

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2588 EGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEE 2667
Cdd:TIGR01612 1699 IGIIEKIKEIAIANKEEIESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGCLETVSK 1778

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2668 R---VAELARDLVEMEQKLLMVTKENKGLTA-----QIQSFGRSMSSLQNSRDHAN----EELDELKRKYDASLKELAQL 2735
Cdd:TIGR01612 1779 EpitYDEIKNTRINAQNEFLKIIEIEKKSKSylddiEAKEFDRIINHFKKKLDHVNdkftKEYSKINEGFDDISKSIENV 1858

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2736 KEQ-------GLLNRERDAL---------------------LSETAFSMNSTEENS--LSHLEKLNQQLLSkdeqllHLS 2785
Cdd:TIGR01612 1859 KNStdenllfDILNKTKDAYagiigkkyysykdeaekifinISKLANSINIQIQNNsgIDLFDNINIAILS------SLD 1932

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2786 SQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSA---------AQPSTSPAEVQSLKKAMSSLQNDRDR 2856
Cdd:TIGR01612 1933 SEKEDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQdtlniifenQQLYEKIQASNELKDTLSDLKYKKEK 2012

                         1610
                   ....*....|....*..
gi 530374448  2857 LLKELKNLQQQYLQINQ 2873
Cdd:TIGR01612 2013 ILNDVKLLLHKFDELNK 2029
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1272-1882 1.27e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.26  E-value: 1.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1272 KAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHL 1351
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1352 RELQPKLDELQKLISKKeedVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1431
Cdd:TIGR04523  203 LSNLKKKIQKNKSLESQ---ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQN 279

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1432 PEEIGEESRAKQQIQRKLQAAlisrkealkENKSLQEELSLARGTIERLTKSLADVESQVSAQNKekdtvlgRLALLQEE 1511
Cdd:TIGR04523  280 NKKIKELEKQLNQLKSEISDL---------NNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNK-------IISQLNEQ 343

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1512 RDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKiaestewqekhkelqKEYEILLQSYENVSN 1591
Cdd:TIGR04523  344 ISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQI---------------NDLESKIQNQEKLNQ 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1592 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKIleleeendrlraevhpag 1671
Cdd:TIGR04523  409 QKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQL------------------ 470

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1672 dtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTnvte 1751
Cdd:TIGR04523  471 -------KVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESK---- 539

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1752 egTQSIPGETEEQDSlsmstrptcsesvpsaksanpaVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLE 1831
Cdd:TIGR04523  540 --ISDLEDELNKDDF----------------------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKE 595

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 530374448  1832 NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEE 1882
Cdd:TIGR04523  596 KEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQE 646
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1259-1495 2.49e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.84  E-value: 2.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1259 ASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKL 1338
Cdd:COG4942    13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1339 ESSQLQIAGLEHlrELQPKLDELQKLISKKEEDV---SYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHD 1415
Cdd:COG4942    93 AELRAELEAQKE--ELAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1416 ERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELslaRGTIERLTKSLADVESQVSAQN 1495
Cdd:COG4942   171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL---EALIARLEAEAAAAAERTPAAG 247
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1291-2222 3.30e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.13  E-value: 3.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1291 STTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEE 1370
Cdd:TIGR00606  166 SEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYEN 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1371 DVSYLSGQLSEKEAALTKIQteiiEQEDLIKALH-TQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKL 1449
Cdd:TIGR00606  246 ELDPLKNRLKEIEHNLSKIM----KLDNEIKALKsRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKEREL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1450 QAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLIT------------ 1517
Cdd:TIGR00606  322 VDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErqiknfhtlvie 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1518 -EMDRSLLENQSLSSSCESLKLALEGLTE--------------DKEKLVKEIESLKSSK------IAESTEWQEKHKELQ 1576
Cdd:TIGR00606  402 rQEDEAKTAAQLCADLQSKERLKQEQADEirdekkglgrtielKKEILEKKQEELKFVIkelqqlEGSSDRILELDQELR 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1577 KEYEILLQSYENVSNEAERIQhvVEAVRQEKQELYGKLRSTEanKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILEL 1656
Cdd:TIGR00606  482 KAERELSKAEKNSLTETLKKE--VKSLQNEKADLDRKLRKLD--QEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSR 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1657 EEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQAN 1736
Cdd:TIGR00606  558 HSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1737 LEATEKHDNQTNVTEEGTQSIPGETEEQDSLsmstrptCSESVPSAKSANPAVSKDFSSHDEINNYlqqIDQLKERIAGL 1816
Cdd:TIGR00606  638 ESDLERLKEEIEKSSKQRAMLAGATAVYSQF-------ITQLTDENQSCCPVCQRVFQTEAELQEF---ISDLQSKLRLA 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1817 EEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDL--EERLMNQL 1894
Cdd:TIGR00606  708 PDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpEEESAKVC 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1895 AELNGSIGNYCQDVTDAQIKNELLESEMK--NLKKCVSELEEEKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPG 1966
Cdd:TIGR00606  788 LTDVTIMERFQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIElnrkliQDQQEQIQHLKSKTN 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1967 N-KSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAElasfk 2045
Cdd:TIGR00606  868 ElKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK----- 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2046 vlLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALrrEKVHLEETIGE 2125
Cdd:TIGR00606  943 --VNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI--DTQKIQERWLQ 1018

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2126 IQVTLNKKDKEVQQLQENLDSTVTQLAAF-TKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEI-----RLKEDNCSV 2199
Cdd:TIGR00606 1019 DNLTLRKRENELKEVEEELKQHLKEMGQMqVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIkhfkkELREPQFRD 1098

                          970       980
                   ....*....|....*....|...
gi 530374448  2200 LKDQLRQMSIHMEELKINISRLE 2222
Cdd:TIGR00606 1099 AEEKYREMMIVMRTTELVNKDLD 1121
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2315-2973 3.38e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 3.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2315 NSKFSYEQLETDLQaSRELTSRLHEEINMKEQKiisllsgkeEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEE 2394
Cdd:TIGR02169  208 EKAERYQALLKEKR-EYEGYELLKEKEALERQK---------EAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2395 NKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2474
Cdd:TIGR02169  278 NKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2475 EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEAnEDLRRSF 2554
Cdd:TIGR02169  358 EYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAI-AGIEAKI 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2555 NALQEEKQDLSKEIESLKVSISQLTRQVTALQEE-----GTLGLYHAQLKVKEEEVHRLSALFSSSQKR----------- 2618
Cdd:TIGR02169  437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQElydlkEEYDRVEKELSKLQRELAEAEAQARASEERvrggraveevl 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2619 ----------IAEL------------------------EEELV---CVQKEAAKKVG----------------------- 2638
Cdd:TIGR02169  517 kasiqgvhgtVAQLgsvgeryataievaagnrlnnvvvEDDAVakeAIELLKRRKAGratflplnkmrderrdlsilsed 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2639 ----------EIEDKLKKELKHLHHDAGIMRNeTETAEE-----RVAELARDLVE----------MEQKLLMVTKENKG- 2692
Cdd:TIGR02169  597 gvigfavdlvEFDPKYEPAFKYVFGDTLVVED-IEAARRlmgkyRMVTLEGELFEksgamtggsrAPRGGILFSRSEPAe 675

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2693 ---LTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQL-KEQGLLNRERDALLSETafsmnsteENSLSHLE 2768
Cdd:TIGR02169  676 lqrLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERL--------EELEEDLS 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2769 KLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHlwnelEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMS 2848
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH-----SRIPEIQAELSKLEEEVSRIEARLREIEQKLN 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2849 SLQNDRDRLLKELKNLQQQYL----QINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWE 2924
Cdd:TIGR02169  823 RLTLEKEYLEKEIQELQEQRIdlkeQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELE 902

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2925 IHERRMKEQY----------LMAISDKDQQLSHLQNLIRELRSSSSQTQPL-KVQYQRQA 2973
Cdd:TIGR02169  903 RKIEELEAQIekkrkrlselKAKLEALEEELSEIEDPKGEDEEIPEEELSLeDVQAELQR 962
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1343-1618 3.44e-06

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 53.01  E-value: 3.44e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1343 LQIAGLEhlRELQPKLDELQKL-----ISKKEED----VSYLSGQLSEKEAALTKIQTeIIEQEDLIKALhtQLEMQAKE 1413
Cdd:PRK05771    9 VLIVTLK--SYKDEVLEALHELgvvhiEDLKEELsnerLRKLRSLLTKLSEALDKLRS-YLPKLNPLREE--KKKVSVKS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1414 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQaaliSRKEALKENKSLQEELSLAR---------GTI-----ER 1479
Cdd:PRK05771   84 LEELIKDVEEELEKIEKEIKELEEEISELENEIKELE----QEIERLEPWGNFDLDLSLLLgfkyvsvfvGTVpedklEE 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1480 LTKSLADVESQVSAQNKEKDTVLgrLALLQEERDKLITEMDRSLLENQSLSSScESLKLALEGLTEDKEKLVKEIESLKs 1559
Cdd:PRK05771  160 LKLESDVENVEYISTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE-GTPSELIREIKEELEEIEKERESLL- 235

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 530374448 1560 SKIAESTEwqekhkelqKEYEILLQSYENVSNEAERiqhvveavrqekQELYGKLRSTE 1618
Cdd:PRK05771  236 EELKELAK---------KYLEELLALYEYLEIELER------------AEALSKFLKTD 273
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 198-417 3.47e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 3.47e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  198 FISTLQAQLSQTQAEQAAQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLR---NTV 274
Cdd:COG4942     9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelAEL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  275 ETEREESKILLEKMELEVAE--RKLSFHNLQEEMHHLL-----EQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILS 347
Cdd:COG4942    89 EKEIAELRAELEAQKEELAEllRALYRLGRQPPLALLLspedfLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448  348 LQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLE------DQLQQKSKEISQFLNRLPLQQHETASQTS 417
Cdd:COG4942   169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAelaaelAELQQEAEELEALIARLEAEAAAAAERTP 244
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 646-1469 3.81e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.05  E-value: 3.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   646 HQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTE 725
Cdd:pfam02463  188 LIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKL 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   726 LRAQVKQLEMNLAEaerqrrldyESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQ 805
Cdd:pfam02463  268 AQVLKENKEEEKEK---------KLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   806 NKESEVLEGAERvrhISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEK 885
Cdd:pfam02463  339 ELEKELKELEIK---REAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   886 FSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQnYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALIN 965
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEK-QELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQK 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   966 RKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLE 1045
Cdd:pfam02463  495 LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELP 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1046 EKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPE 1125
Cdd:pfam02463  575 LGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSL 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1126 LEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVR 1205
Cdd:pfam02463  655 EEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKI 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1206 ESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsedasalqggTSVAQIKAQLKEIEAEKVEL 1285
Cdd:pfam02463  735 NEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELA-----------------EEREKTEKLKVEEEKEEKLK 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1286 ELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLI 1365
Cdd:pfam02463  798 AQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEE 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1366 SKKEEDVSYLSGQLSEKEAALTKIQTEI--IEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQ 1443
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEEsqKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEE 957

                          810       820
                   ....*....|....*....|....*.
gi 530374448  1444 QIQRKLQAALISRKEALKENKSLQEE 1469
Cdd:pfam02463  958 EEERNKRLLLAKEELGKVNLMAIEEF 983
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2460-2868 7.16e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.99  E-value: 7.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2460 QLIQEAAAENNKLKEEIRGLrshmDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELEnkyakleek 2539
Cdd:TIGR02169  146 DFISMSPVERRKIIDEIAGV----AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--------- 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2540 lkeseeanedlrrsFNALQEEKQD-----LSKEIESLKVSISQLTRQVTALqeegtlglyhaqlkvkEEEVHRLSALFSS 2614
Cdd:TIGR02169  213 --------------YQALLKEKREyegyeLLKEKEALERQKEAIERQLASL----------------EEELEKLTEEISE 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2615 SQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHhdagimrNETETAEERVAELARDLVEMEQKLLMVTKENKGLT 2694
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELE-------AEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2695 AQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAfsmnsteENSLSHLEKLNQQL 2774
Cdd:TIGR02169  336 AEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL-------EKLKREINELKREL 408

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2775 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKfrksEEGKQRSAAqpstspAEVQSLKKAMSSLQNDR 2854
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK----QEWKLEQLA------ADLSKYEQELYDLKEEY 478

                          410
                   ....*....|....
gi 530374448  2855 DRLLKELKNLQQQY 2868
Cdd:TIGR02169  479 DRVEKELSKLQREL 492
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1354-1899 7.53e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 7.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1354 LQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQT--EIIEQ----------------EDLIKALHTQLEMQAKEHD 1415
Cdd:pfam15921  262 LQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSqlEIIQEqarnqnsmymrqlsdlESTVSQLRSELREAKRMYE 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1416 ERIKQLQ-------VELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEAL----KENKSLQEELSLARGTIERLTKSL 1484
Cdd:pfam15921  342 DKIEELEkqlvlanSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELslekEQNKRLWDRDTGNSITIDHLRREL 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1485 ADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAE 1564
Cdd:pfam15921  422 DDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDL 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1565 STEWQEKHK----------ELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQ---EA 1631
Cdd:pfam15921  502 TASLQEKERaieatnaeitKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQlvgQH 581

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1632 EQEMEEMKEKMRKFAKSKQQKILELEE-------ENDRLRAEVHPAGDTAKECMEtLLSSNASMKEELERVKMEYETLSK 1704
Cdd:pfam15921  582 GRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkKDAKIRELEARVSDLELEKVK-LVNAGSERLRAVKDIKQERDQLLN 660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1705 KFQSLMSEKDSLSEEVQDLKHQIEGNvskqanleaTEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKS 1784
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLKRNFRNK---------SEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMG 731

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1785 ANPAVSKDFSSHDEINNYLQQIDQL-----KERiAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMN 1859
Cdd:pfam15921  732 MQKQITAKRGQIDALQSKIQFLEEAmtnanKEK-HFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANME 810

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 530374448  1860 LLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNG 1899
Cdd:pfam15921  811 VALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
PTZ00121 PTZ00121
MAEBL; Provisional
 904-1608 7.73e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 7.73e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  904 RAEEAKK-EQVEEDNEVSSGLK-------QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSR 975
Cdd:PTZ00121 1177 KAEAARKaEEVRKAEELRKAEDarkaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK 1256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  976 LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEE-QF 1054
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAaKK 1336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1055 QALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNtDASDGDSVALVKETVVISPPCTGSSEHWKPELEE--KILA 1132
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE-AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElkKAAA 1415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1133 LEKEKEQLQKKLQEAltsRKAILKKAQEKERHLREELKQQKDDYNRLQEQfdEQSKENENIGDQLRQLQIQVRESIDGKL 1212
Cdd:PTZ00121 1416 AKKKADEAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEA--KKKAEEAKKADEAKKKAEEAKKADEAKK 1490

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1213 PSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESnlcpDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVElelkvsst 1292
Cdd:PTZ00121 1491 KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKA----DEAKKAEEAKKADEAKKAEEKKKADELKKAEELK-------- 1558

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1293 TSELTKKSEEVFQLQEQINKQGLEIESLKTVshEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELqklisKKEEDV 1372
Cdd:PTZ00121 1559 KAEEKKKAEEAKKAEEDKNMALRKAEEAKKA--EEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEEL-----KKAEEE 1631

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1373 SYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQ--RKLQ 1450
Cdd:PTZ00121 1632 KKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEelKKKE 1711

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1451 AALISRKEALK------------------ENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRlaLLQEER 1512
Cdd:PTZ00121 1712 AEEKKKAEELKkaeeenkikaeeakkeaeEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE--ELDEED 1789

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1513 DKLITEMDRSLLENQSLSSSCES----LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYEN 1588
Cdd:PTZ00121 1790 EKRRMEVDKKIKDIFDNFANIIEggkeGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEAD 1869

                         730       740
                  ....*....|....*....|
gi 530374448 1589 VSNEAERIQHVVEAVRQEKQ 1608
Cdd:PTZ00121 1870 FNKEKDLKEDDEEEIEEADE 1889
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2074-2756 7.99e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 7.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2074 ESVKSQMKQKDEDLERRLEQAEEKHLKEK--------------KNMQEKLDAL----RREKVHLEETIGEIQVTLNKKDK 2135
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEKQKfylrqsvidlqtklQEMQMERDAMadirRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2136 EVQQLQENLDSTVTQLAAFTKSMSS----LQDDRDRVIDEAKKWERKFSDAIQSKEEEIRlkeDNCSVLKDQLRQMSIHM 2211
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLShegvLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---SLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2212 EELKINISRLEHDKQIWESKAQTEVQL----QQKVCDTLQGENKELLSQLEETRHlyhSSQNELAKLESELKSLKDQLTD 2287
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNKIELllqqHQDRIEQLISEHEVEITGLTEKAS---SARSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2288 lSNSLEKCkeQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ-----ASRELTSRLHEEINMKE---------QKIISLLS 2353
Cdd:pfam15921  311 -QNSMYMR--QLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlANSELTEARTERDQFSQesgnlddqlQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2354 GKEEAIQ-----------------VAIAELRQQHDK---EIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIK 2413
Cdd:pfam15921  388 KREKELSlekeqnkrlwdrdtgnsITIDHLRRELDDrnmEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLT 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2414 KENIQQKAQLDSFVKSMSSLQ---NDRDRIVGDYQqleerhlSIILEKDQLIQEAAAENNKLK-------EEIRGLRSHM 2483
Cdd:pfam15921  468 AQLESTKEMLRKVVEELTAKKmtlESSERTVSDLT-------ASLQEKERAIEATNAEITKLRsrvdlklQELQHLKNEG 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2484 DDLNSENAKLDAELIQYREDlNQVITIKDSQQKQLLEVQLQQNKELenkyAKLEEKLKESEEANEDLRRSFNALQEEKQD 2563
Cdd:pfam15921  541 DHLRNVQTECEALKLQMAEK-DKVIEILRQQIENMTQLVGQHGRTA----GAMQVEKAQLEKEINDRRLELQEFKILKDK 615

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2564 LSKEIESLKVSISQLTRQVTALQEEGTLGLyHAQLKVKEEEVHRLSALfSSSQKRIAELEEELVCVQKEAAKKVGEIE-- 2641
Cdd:pfam15921  616 KDAKIRELEARVSDLELEKVKLVNAGSERL-RAVKDIKQERDQLLNEV-KTSRNELNSLSEDYEVLKRNFRNKSEEMEtt 693

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2642 -DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDE 2720
Cdd:pfam15921  694 tNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNK 773

                          730       740       750
                   ....*....|....*....|....*....|....*.
gi 530374448  2721 LKRKYDASLKELAQLKEQGLLNRERDALLSETAFSM 2756
Cdd:pfam15921  774 LSQELSTVATEKNKMAGELEVLRSQERRLKEKVANM 809
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2257-3021 1.07e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.66  E-value: 1.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2257 LEETRHLYHSSQ---NELAKLESELK-SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRE 2332
Cdd:pfam15921   80 LEEYSHQVKDLQrrlNESNELHEKQKfYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKC 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2333 LTSRLHEEINMKEQKIISLLSGKE---EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETl 2409
Cdd:pfam15921  160 LKEDMLEDSNTQIEQLRKMMLSHEgvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKG- 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2410 KTIKKENIQQKAQLDSFVKSMSSLQNDRDRIvgdyQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNS- 2488
Cdd:pfam15921  239 RIFPVEDQLEALKSESQNKIELLLQQHQDRI----EQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSm 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2489 ---ENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLS 2565
Cdd:pfam15921  315 ymrQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELS 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2566 KEIESLKVSISQLTRQVTalqeegTLGLYHAQLKVKEEEVHRLSALFSSSQKRI-AELEEELVCVQ--KEAAKKVGEIED 2642
Cdd:pfam15921  395 LEKEQNKRLWDRDTGNSI------TIDHLRRELDDRNMEVQRLEALLKAMKSECqGQMERQMAAIQgkNESLEKVSSLTA 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2643 KLkkelkhlhhdagimrnetETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSlqnsrdhANEELDELK 2722
Cdd:pfam15921  469 QL------------------ESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEA-------TNAEITKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2723 RKYDASLKELAQLKEQGllnrerDALlsetafsmnsteENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAM 2802
Cdd:pfam15921  524 SRVDLKLQELQHLKNEG------DHL------------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTA 585

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2803 ASLQNERDHLWNELE---------KFRKSEEGKQRSAAQPSTSPAEVQSLK---------KAMSSLQNDRDRLLKELKNL 2864
Cdd:pfam15921  586 GAMQVEKAQLEKEINdrrlelqefKILKDKKDAKIRELEARVSDLELEKVKlvnagserlRAVKDIKQERDQLLNEVKTS 665

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2865 QQQYLQINQEITELHplkaqlQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWE---IHERRMKEQYLMAISDK 2941
Cdd:pfam15921  666 RNELNSLSEDYEVLK------RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdGHAMKVAMGMQKQITAK 739

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2942 DQQLSHLQNLIR---ELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSN 3018
Cdd:pfam15921  740 RGQIDALQSKIQfleEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQ 819


                   ...
gi 530374448  3019 FSQ 3021
Cdd:pfam15921  820 FAE 822
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
666-871 1.10e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.17  E-value: 1.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  666 KAQEIYEKNLDEKAKEISNLNQLIEEFKKNADnnssaFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEMNLAEAERQr 744
Cdd:COG3206   175 KALEFLEEQLPELRKELEEAEAALEEFRQKNG-----LVDLSEEAKLLLQQLSELeSQLAEARAELAEAEARLAALRAQ- 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  745 rLDYESQTAHDNLLTEQIHSLSIEakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRH---- 820
Cdd:COG3206   249 -LGSGPDALPELLQSPVIQQLRAQ-------LAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILAslea 320

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 530374448  821 ----ISSKVEELSQALSQKELEITKMDQL---LLEKKRDVETLQQTIEEKDQQVTEIS 871
Cdd:COG3206   321 eleaLQAREASLQAQLAQLEARLAELPELeaeLRRLEREVEVARELYESLLQRLEEAR 378
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1266-1424 1.14e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 49.54  E-value: 1.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1266 TSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLktvsheaevhaESLQQKLESSQLQI 1345
Cdd:COG1579    17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEV-----------EARIKKYEEQLGNV 85

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530374448 1346 AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1424
Cdd:COG1579    86 RNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2355-3064 1.20e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2355 KEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDsfvKSMSSLQ 2434
Cdd:TIGR02169  185 NIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELE---KLTEEIS 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2435 NDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQ 2514
Cdd:TIGR02169  262 ELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2515 QKQLLEVQLQQNK------ELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLtrQVTALQEE 2588
Cdd:TIGR02169  342 EREIEEERKRRDKlteeyaELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRL--QEELQRLS 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2589 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELvcvqKEAAKKVGEIEDKLKKelkhlhhdagiMRNETETAEER 2668
Cdd:TIGR02169  420 EELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL----EQLAADLSKYEQELYD-----------LKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2669 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRdhanEELDELKRKYDASLkELAQLKEQGLLNRERDAL 2748
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTV----AQLGSVGERYATAI-EVAAGNRLNNVVVEDDAV 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2749 LSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQV---QSFSKA----------MASLQNERDHLWN- 2814
Cdd:TIGR02169  560 AKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVefdPKYEPAfkyvfgdtlvVEDIEAARRLMGKy 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2815 -----ELEKFRKS------EEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELH---- 2879
Cdd:TIGR02169  640 rmvtlEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASrkig 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2880 PLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLR--MEKSSWEIHERRMK-EQYLMAISDKDQQLSH--------- 2947
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKseLKELEARIEELEEDlHKLEEALNDLEARLSHsripeiqae 799

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2948 LQNLIRELRSSSSQTQPLKVQYQRQASPETSASpDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKN 3027
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLE-KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878

                          730       740       750
                   ....*....|....*....|....*....|....*..
gi 530374448  3028 TLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQEL 3064
Cdd:TIGR02169  879 DLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 957-1834 1.71e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.84  E-value: 1.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   957 RKLQAALinrkELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE-NKEYSEKCVTSKCQEIEIYLKQ------T 1029
Cdd:TIGR02169  170 RKKEKAL----EELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQkeaierQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1030 ISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKT-NQIDLLQAEISENQAIIQKLITSNTDASDgdSVALVKET 1108
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGeEEQLRVKEKIGELEAEIASLERSIAEKER--ELEDAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1109 VVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKE---RHLREELKQQKDDYNRLQEQFDE 1185
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDkefAETRDELKDYREKLEKLKREINE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1186 QSKENENIGDQLRQLQIQVREsIDGKLPSTDQQ--ESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQ 1263
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELAD-LNAAIAGIEAKinELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1264 GGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEE-----VFQLQEQINKQGLEIES-----LKTVSHEAEVHAES 1333
Cdd:TIGR02169  483 KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtVAQLGSVGERYATAIEVaagnrLNNVVVEDDAVAKE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1334 LQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKI---QTEIIEQEDLIKALHTQLEMQ 1410
Cdd:TIGR02169  563 AIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYvfgDTLVVEDIEAARRLMGKYRMV 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1411 AKEHDERIK---------QLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLT 1481
Cdd:TIGR02169  643 TLEGELFEKsgamtggsrAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1482 KSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRsllenqslssscesLKLALEGLTEDKEKLVKEIESLKSSK 1561
Cdd:TIGR02169  723 KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKE--------------LEARIEELEEDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1562 IAEstEWQEKHKELQKEYEIlLQSYENVSNEAERI----QHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAeqemee 1637
Cdd:TIGR02169  789 SHS--RIPEIQAELSKLEEE-VSRIEARLREIEQKlnrlTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENL------ 859

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1638 mkekmrkfakskQQKILELEEENDRLRAEVhpagdtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLS 1717
Cdd:TIGR02169  860 ------------NGKKEELEEELEELEAAL-----------RDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1718 EEVQDLKHQIEGNVSKQANLEATEKHDnqtnvteegtQSIPGETEEQDSLSMsTRPTCSESVPSAKSANpavskdFSSHD 1797
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGED----------EEIPEEELSLEDVQA-ELQRVEEEIRALEPVN------MLAIQ 979

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 530374448  1798 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEK 1834
Cdd:TIGR02169  980 EYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1795-2497 1.73e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.99  E-value: 1.73e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1795 SHDEINNYLQQIDQlkerIAGLEEEKQKnkefSQTLENEKNTLLSQIStkdgELKMLQEEVTKMNLlnqQIQEELSRVTK 1874
Cdd:pfam12128  219 NRQQVEHWIRDIQA----IAGIMKIRPE----FTKLQQEFNTLESAEL----RLSHLHFGYKSDET---LIASRQEERQE 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1875 LKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcvSELEEEKQQLVKEKTkVESEIrkEY 1954
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLPS-WQSEL--EN 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1955 LEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQL----QKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2030
Cdd:pfam12128  359 LEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIagikDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEE 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2031 VEHRKKAQAELasfKVLLDDTQSEaarvladnlklkKELQSNKESVKSQMKQKDEDLERR---LEQAEEKHLKEKKNMQE 2107
Cdd:pfam12128  439 EYRLKSRLGEL---KLRLNQATAT------------PELLLQLENFDERIERAREEQEAAnaeVERLQSELRQARKRRDQ 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2108 KLDALRREKVHLEETIGEIqvtlnkkdkevQQLQENLDSTVTQLAAFTKSMSSL-QDDRDRVIDEAKKWErkfSDAIQSK 2186
Cdd:pfam12128  504 ASEALRQASRRLEERQSAL-----------DELELQLFPQAGTLLHFLRKEAPDwEQSIGKVISPELLHR---TDLDPEV 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2187 EEEIRLKEDNCSVLKDQLRQMSI-----HMEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETR 2261
Cdd:pfam12128  570 WDGSVGGELNLYGVKLDLKRIDVpewaaSEEELRERLDKAEEALQ----SAREKQAAAEEQLVQANGELEKASREETFAR 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2262 HLYHSSQNELAKLESELKSLKDQLTD-LSNSLEKCKEQKGNLEGIIRQQEADIQNSkfsyeqletdLQASRELTSRLHEE 2340
Cdd:pfam12128  646 TALKNARLDLRRLFDEKQSEKDKKNKaLAERKDSANERLNSLEAQLKQLDKKHQAW----------LEEQKEQKREARTE 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2341 INMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKeNIQQK 2420
Cdd:pfam12128  716 KQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAV-RRQEV 794

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530374448  2421 AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKdqLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAEL 2497
Cdd:pfam12128  795 LRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLAR--LIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEM 869
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1547-2875 2.02e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 50.82  E-value: 2.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1547 KEKLVKEIESLKSSKIAESTEWQEKHKELQKEYE-------ILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTeA 1619
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEeenedsiHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNI-S 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1620 NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRaevhpagdtakecmetllssnASMKEELERV-KME 1698
Cdd:TIGR01612  614 DKNEYIKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIY---------------------STIKSELSKIyEDD 672

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1699 YETLSKKFQSLMSEKDSLSEE----VQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPT 1774
Cdd:TIGR01612  673 IDALYNELSSIVKENAIDNTEdkakLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKD 752

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1775 CSESVPSAKSANPAVSKDFSSH----DEINNYLQQIDQLKERIAG-LEEEKQKNKEFSQTLENEKNtLLSQISTKDGELK 1849
Cdd:TIGR01612  753 LNKILEDFKNKEKELSNKINDYakekDELNKYKSKISEIKNHYNDqINIDNIKDEDAKQNYDKSKE-YIKTISIKEDEIF 831

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1850 MLQEEVTKMNllnqqiQEELSRVTKLKETAEEEKDDLEERlMNQLAELNGSIGNycqdvtdaQIKNELLESEMKNLKKCV 1929
Cdd:TIGR01612  832 KIINEMKFMK------DDFLNKVDKFINFENNCKEKIDSE-HEQFAELTNKIKA--------EISDDKLNDYEKKFNDSK 896

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1930 SELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKE--LQELLKEKQQEVKQLQKDCIRYQ--------EKI 1999
Cdd:TIGR01612  897 SLINEINKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQniLKEILNKNIDTIKESNLIEKSYKdkfdntliDKI 976

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2000 SALERTVKALEFVQTESQKDLEIT-----KENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKL--KKELQSN 2072
Cdd:TIGR01612  977 NELDKAFKDASLNDYEAKNNELIKyfndlKANLGKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIaiHTSIYNI 1056

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2073 KESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeiqvtlnKKDKEVQQLQENLDSTVTQLA 2152
Cdd:TIGR01612 1057 IDEIEKEIGKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDFGKEENI--------KYADEINKIKDDIKNLDQKID 1128

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2153 AFTKSMSSLQDDRDRVIDEAK----KWERKFSDAIQSKE-EEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQI 2227
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKaqinDLEDVADKAISNDDpEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEIEKDKTS 1208

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2228 WESKAQTEVQLQQKVcdtlqgeNKELLSQLEEtrhlyhssqnELAKLESELKSLKDQLTDLSNSLEKCKEQKgNLEGIIR 2307
Cdd:TIGR01612 1209 LEEVKGINLSYGKNL-------GKLFLEKIDE----------EKKKSEHMIKAMEAYIEDLDEIKEKSPEIE-NEMGIEM 1270

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2308 QQEADIQNSKFSYEQLETDLQASRELTSRLhEEINMKEQKIISLLSGK------EEAIQVAIAElRQQHDKEIKELENLL 2381
Cdd:TIGR01612 1271 DIKAEMETFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEEsdindiKKELQKNLLD-AQKHNSDINLYLNEI 1348

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2382 SQEEEENIVLEEEN--KKAVDKTNQLMETLKTIKKEnIQQKAQLDSFVKSMSSLQNDRDRIVG--DYQQLEERHLSIILE 2457
Cdd:TIGR01612 1349 ANIYNILKLNKIKKiiDEVKEYTKEIEENNKNIKDE-LDKSEKLIKKIKDDINLEECKSKIEStlDDKDIDECIKKIKEL 1427

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2458 KDQLIQEAAAENNKLKEEirglrshmdDLNSENAKLDAELIQYREDLNQ-VITIKDSQQKQLLEV---QLQQNKELENKY 2533
Cdd:TIGR01612 1428 KNHILSEESNIDTYFKNA---------DENNENVLLLFKNIEMADNKSQhILKIKKDNATNDHDFninELKEHIDKSKGC 1498

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2534 AKLEEKLKESEEANEDLRRSFNalQEEKQDLSKEIE-SLKVSISQLTRQVTALQEEgtLGLYHAQLKVKEEevhrlsalf 2612
Cdd:TIGR01612 1499 KDEADKNAKAIEKNKELFEQYK--KDVTELLNKYSAlAIKNKFAKTKKDSEIIIKE--IKDAHKKFILEAE--------- 1565

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2613 sSSQKRIAELEEELVCVQKEAAK-------------KVGEIEDKLKKeLKHLHHDAGIMRNETETAEERVAELARDLVEM 2679
Cdd:TIGR01612 1566 -KSEQKIKEIKKEKFRIEDDAAKndksnkaaidiqlSLENFENKFLK-ISDIKKKINDCLKETESIEKKISSFSIDSQDT 1643

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2680 EqkllmvTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDEL--------------KRKYDASLKElaQLKEQGLLNRER 2745
Cdd:TIGR01612 1644 E------LKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELdseiekieidvdqhKKNYEIGIIE--KIKEIAIANKEE 1715

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2746 dalLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMAS--------------LQNERDH 2811
Cdd:TIGR01612 1716 ---IESIKELIEPTIENLISSFNTNDLEGIDPNEKLEEYNTEIGDIYEEFIELYNIIAGcletvskepitydeIKNTRIN 1792

                         1370      1380      1390      1400      1410      1420
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530374448  2812 LWNELEKFRKSEegKQRSAAQPSTSPAEVQSLKKAM-SSLQNDRDRLLKELKNLQQQYLQINQEI 2875
Cdd:TIGR01612 1793 AQNEFLKIIEIE--KKSKSYLDDIEAKEFDRIINHFkKKLDHVNDKFTKEYSKINEGFDDISKSI 1855
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2313-2868 2.10e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 2.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2313 IQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKI--ISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQEEEENIV 2390
Cdd:PRK03918  171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLreINEISSELPELREELEKLEKEV-KELEELKEEIEELEKELES 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2391 LEEENKKAVDKTNQLMETLKTIKKEniqqKAQLDSFVKSMSSLQNDRDRivgdYQQLEERHLSIILEKDQLIQEAAaenn 2470
Cdd:PRK03918  250 LEGSKRKLEEKIRELEERIEELKKE----IEELEEKVKELKELKEKAEE----YIKLSEFYEEYLDELREIEKRLS---- 317

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2471 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQK----QLLEVQLQQNKELENKYAKL--EEKLKESE 2544
Cdd:PRK03918  318 RLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELyeeaKAKKEELERLKKRLTGLTPEklEKELEELE 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2545 EANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT----------RQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSS 2614
Cdd:PRK03918  398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2615 SQKRIAELEEEL-----VCVQKEAAKKVGEIEDKLKK-----------ELKHLHHDAGIMRNETETAE---ERVAELARD 2675
Cdd:PRK03918  478 LRKELRELEKVLkkeseLIKLKELAEQLKELEEKLKKynleelekkaeEYEKLKEKLIKLKGEIKSLKkelEKLEELKKK 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2676 LVEMEQKLLMVTKENKGLTAQIQSFGRSmsslqnSRDHANEELDELKRKYDA--SLKELAQLKEQGLLNRERDALLSETA 2753
Cdd:PRK03918  558 LAELEKKLDELEEELAELLKELEELGFE------SVEELEERLKELEPFYNEylELKDAEKELEREEKELKKLEEELDKA 631

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2754 FSMNSTEENSLSHLEKLNQQLLSKDEQLLHlssqlEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQP 2833
Cdd:PRK03918  632 FEELAETEKRLEELRKELEELEKKYSEEEY-----EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                         570       580       590
                  ....*....|....*....|....*....|....*
gi 530374448 2834 STSPAEVQSLKKAMSSLQNDRDRlLKELKNLQQQY 2868
Cdd:PRK03918  707 EKAKKELEKLEKALERVEELREK-VKKYKALLKER 740
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1540-2146 2.41e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 2.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1540 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEIL---LQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS 1616
Cdd:TIGR04523   98 INKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIdkfLTEIKKKEKELEKLNNKYNDLKKQKEELENELNL 177

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1617 TEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQ------KILELEEENDRLRAEVHPAGD----------TAKECMET 1680
Cdd:TIGR04523  178 LEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKnkslesQISELKKQNNQLKDNIEKKQQeinektteisNTQTQLNQ 257

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1681 LLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGE 1760
Cdd:TIGR04523  258 LKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKII 337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1761 TEEQDSLSmstrptcsesvpsaksanpAVSKDFSSHDEINNYLQ-QIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLS 1839
Cdd:TIGR04523  338 SQLNEQIS-------------------QLKKELTNSESENSEKQrELEEKQNEIEKLKKENQSYKQEIKNLESQINDLES 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1840 QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEerlmNQLAELNGSIGNYCQDVTDAQIKNELLE 1919
Cdd:TIGR04523  399 KIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLT----NQDSVKELIIKNLDNTRESLETQLKVLS 474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1920 SEMKNLKkcvSELEEEKQQLVKEktkvESEIRKEYLEKIQGAQKepgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKI 1999
Cdd:TIGR04523  475 RSINKIK---QNLEQKQKELKSK----EKELKKLNEEKKELEEK-------VKDLTKKISSLKEKIEKLESEKKEKESKI 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2000 SALERTVKALEFvqtesqkdlEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQ 2079
Cdd:TIGR04523  541 SDLEDELNKDDF---------ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK 611

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530374448  2080 MKQKDEDLErRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDS 2146
Cdd:TIGR04523  612 ISSLEKELE-KAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1128-1357 2.66e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1128 EKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1207
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAEL----EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1208 idgklpstdQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTS------VAQIKAQLKEIEAE 1281
Cdd:COG4942    95 ---------LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAparreqAEELRADLAELAAL 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448 1282 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPK 1357
Cdd:COG4942   166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
46 PHA02562
endonuclease subunit; Provisional
 1797-1957 3.10e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 49.63  E-value: 3.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1797 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLnQQIQEELSRVTKLK 1876
Cdd:PHA02562  227 EEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCT-QQISEGPDRITKIK 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1877 E---------TAEEEKDDLEERLMNQLA-------ELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLV 1940
Cdd:PHA02562  306 DklkelqhslEKLDTAIDELEEIMDEFNeqskkllELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQ 385

                         170
                  ....*....|....*..
gi 530374448 1941 KEKTKVESEIRKEYLEK 1957
Cdd:PHA02562  386 DELDKIVKTKSELVKEK 402
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2202-2818 3.54e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.91  E-value: 3.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2202 DQLRQMSIHMEELKINISRLEHDKQIWES--KAQTEVQLQQKVCDTLQGENKELLSQLEETRHlyHSSQNELAKLESELK 2279
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLRAALRLWFAQRRLELLEAEL--EELRAELARLEAELE 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2280 SLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ-EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEA 2358
Cdd:COG4913   313 RLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEF--------AA 384

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2359 IQVAIAELRQQHDKEIKELENLLSQEEEENivleeenKKAVDKTNQLMETLKTIKkeniQQKAQLDSFVKSM-----SSL 2433
Cdd:COG4913   385 LRAEAAALLEALEEELEALEEALAEAEAAL-------RDLRRELRELEAEIASLE----RRKSNIPARLLALrdalaEAL 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2434 QNDRD--RIVGDYQQLEERH---------------LSIILEKDQLIQEAAA-ENNKLKEEIRGLRSHMDDLNSENAKLDA 2495
Cdd:COG4913   454 GLDEAelPFVGELIEVRPEEerwrgaiervlggfaLTLLVPPEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDP 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2496 EliqyreDLNQVITIKDSQQKQLLEVQLQqnkelenkyakleeklkeseeanedlrRSFNALQEEkqdlskeieslkvSI 2575
Cdd:COG4913   534 D------SLAGKLDFKPHPFRAWLEAELG---------------------------RRFDYVCVD-------------SP 567

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2576 SQLTRQVTALQEEGTL-GLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKkVGEIEDKLKKELKHLH-- 2652
Cdd:COG4913   568 EELRRHPRAITRAGQVkGNGTRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAE-AEERLEALEAELDALQer 646

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2653 HDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAqiqsfgrsmssLQNSRDHANEELDELKRKYDASLKEL 2732
Cdd:COG4913   647 REALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA-----------LEEQLEELEAELEELEEELDELKGEI 715

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2733 AQL-KEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLsKDEQLLHLSSQLEDSYnqvqsfskamASLQNERDH 2811
Cdd:COG4913   716 GRLeKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAL-GDAVERELRENLEERI----------DALRARLNR 784


                  ....*..
gi 530374448 2812 LWNELEK 2818
Cdd:COG4913   785 AEEELER 791
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1272-1480 3.86e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 3.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1272 KAQLKEIEAEKVELELKVSsttsELTKKSEEVFQLQEQINKQGLEIESLKTVShEAEVHAESLQQKLESSQLQiagLEHL 1351
Cdd:COG4913   609 RAKLAALEAELAELEEELA----EAEERLEALEAELDALQERREALQRLAEYS-WDEIDVASAEREIAELEAE---LERL 680

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1352 RELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEmKQK 1431
Cdd:COG4913   681 DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE----AAEDLARLELRALLE-ERF 755

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 530374448 1432 PEEIGEESRakQQIQRKLQAALisrkealkenKSLQEELSLARGTIERL 1480
Cdd:COG4913   756 AAALGDAVE--RELRENLEERI----------DALRARLNRAEEELERA 792
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 129-1012 3.93e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 3.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   129 EEQLSKHDKSSTEEEMEIEKIKHKLQEKEELIStlqaQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQ 208
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEY----YQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   209 TQAEQAAQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKM 288
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   289 ELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKT--GQELQSACDALKDQN 366
Cdd:pfam02463  336 EIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELElkSEEEKEAQLLLELAR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   367 SKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEgtqaVTEENIASLQKRVVELEN 446
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDL----LKETQLVKLQEQLELLLS 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   447 EKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVL 526
Cdd:pfam02463  492 RQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALT 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   527 LLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQmegeGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQAST 606
Cdd:pfam02463  572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLD----KATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESG 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   607 EHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLN 686
Cdd:pfam02463  648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   687 QLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLS 766
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   767 IEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLL 846
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDE 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   847 LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQN 926
Cdd:pfam02463  888 LESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLL 967

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   927 YDEMSPAG------QISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGE 1000
Cdd:pfam02463  968 AKEELGKVnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKEFLELFVSINKGWNKVFFYLELGGSAE 1047

                          890
                   ....*....|..
gi 530374448  1001 VEEDKENKEYSE 1012
Cdd:pfam02463 1048 LRLEDPDDPFSG 1059
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1795-2312 4.65e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.35  E-value: 4.65e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1795 SHDEINNYLQQ-IDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQistkdgeLKMLQEEVTKMN-LLNQQIQEELSRV 1872
Cdd:pfam15921  254 SQNKIELLLQQhQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQ-------LEIIQEQARNQNsMYMRQLSDLESTV 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1873 TKLKETAEEEKDDLEERLmnqlAELNGSIGNYCQDVTDAQIKNELLESEMKNLkkcvselEEEKQQLVKEKTKVESEIRK 1952
Cdd:pfam15921  327 SQLRSELREAKRMYEDKI----EELEKQLVLANSELTEARTERDQFSQESGNL-------DDQLQKLLADLHKREKELSL 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1953 EYLEKIQGAQKEPGNKSHAKELQELLKEKQQEV-------KQLQKDCI-RYQEKISALERTVKALEFVQTESQKdLEITK 2024
Cdd:pfam15921  396 EKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVqrleallKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQ-LESTK 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2025 ENLAQAVEHRKKAQAELASFKVLLDD--------------TQSEAARVLAD-NLKLK------------KELQSNKESVK 2077
Cdd:pfam15921  475 EMLRKVVEELTAKKMTLESSERTVSDltaslqekeraieaTNAEITKLRSRvDLKLQelqhlknegdhlRNVQTECEALK 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2078 SQMKQKDEDLERrLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK----KDKEVQQLQEnLDSTVTQLAA 2153
Cdd:pfam15921  555 LQMAEKDKVIEI-LRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilKDKKDAKIRE-LEARVSDLEL 632

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2154 FTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHME--------ELKINISRLEHDK 2225
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMEtttnklkmQLKSAQSELEQTR 712

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2226 QIWESKA-------------QTEVQLQQKVCDTLQGENK---ELLSQLEETRHLYHSSQNELAK---------------- 2273
Cdd:pfam15921  713 NTLKSMEgsdghamkvamgmQKQITAKRGQIDALQSKIQfleEAMTNANKEKHFLKEEKNKLSQelstvateknkmagel 792

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 530374448  2274 --LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEAD 2312
Cdd:pfam15921  793 evLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQE 833
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 883-1601 5.44e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 5.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   883 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEfDLLKKENEQRKRKLQAA 962
Cdd:TIGR00618  187 AKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQK-REAQEEQLKKQQLLKQL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   963 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRK 1042
Cdd:TIGR00618  266 RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRR 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1043 DLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHW 1122
Cdd:TIGR00618  346 LLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQ 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1123 KPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDdynrlQEQFDEQSKENENIGDQLRQLQI 1202
Cdd:TIGR00618  426 LAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-----KEQIHLQETRKKAVVLARLLELQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1203 QVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNlcpdwpshSEDASALQGGTSVAQIKAQLKEIEAEK 1282
Cdd:TIGR00618  501 EEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE--------DVYHQLTSERKQRASLKEQMQEIQQSF 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1283 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE----------SLQQKLESSQLQIAGLEHLR 1352
Cdd:TIGR00618  573 SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpeqdlqdvrlHLQQCSQELALKLTALHALQ 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1353 ELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDL--IKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1430
Cdd:TIGR00618  653 LTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLaqCQTLLRELETHIEEYDREFNEIENASSSLGS 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1431 kpeEIGEESRAKQQIQRKLQAaliSRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1510
Cdd:TIGR00618  733 ---DLAAREDALNQSLKELMH---QARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1511 ERDklitemdrsllenqslssscESLKLALEGLTEDKEKLVKEIESLKsSKIAESTEWQEKHKELQKEYEILLQSYENVS 1590
Cdd:TIGR00618  807 EIG--------------------QEIPSDEDILNLQCETLVQEEEQFL-SRLEEKSATLGEITHQLLKYEECSKQLAQLT 865

                          730
                   ....*....|.
gi 530374448  1591 NEAERIQHVVE 1601
Cdd:TIGR00618  866 QEQAKIIQLSD 876
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1788-2026 5.60e-05

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 49.45  E-value: 5.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1788 AVSKDFSSHDEINNYLQQIDQLKERIAgleeEKQKNKEFSQTLENEKNTLLSQISTKDGELkmlqeEVTKMNLLNQQIQE 1867
Cdd:NF012221 1536 ATSESSQQADAVSKHAKQDDAAQNALA----DKERAEADRQRLEQEKQQQLAAISGSQSQL-----ESTDQNALETNGQA 1606

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1868 ELSRVTKLKETAEEEKDDLEERL--MNQLAELNGSIGN-YCQDVTDAQIKNelLESEMKNLKKCVSE-LEEEKQQLVKEK 1943
Cdd:NF012221 1607 QRDAILEESRAVTKELTTLAQGLdaLDSQATYAGESGDqWRNPFAGGLLDR--VQEQLDDAKKISGKqLADAKQRHVDNQ 1684

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1944 TKVESEIRKEYLEKIQGAQKEPG-------NKSHAKELQELLKEKQQEVKQLQKDC-IRYQEKISALERTVKALEFVQTE 2015
Cdd:NF012221 1685 QKVKDAVAKSEAGVAQGEQNQANaeqdiddAKADAEKRKDDALAKQNEAQQAESDAnAAANDAQSRGEQDASAAENKANQ 1764

                         250
                  ....*....|.
gi 530374448 2016 SQKDLEITKEN 2026
Cdd:NF012221 1765 AQADAKGAKQD 1775
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1348-1990 5.90e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 5.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1348 LEHLRELQPKLDELQKLISKKEEdvsyLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDerikqlqvELCE 1427
Cdd:PRK03918  168 GEVIKEIKRRIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK--------ELEE 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1428 MKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSladvesqvsaqnkekdtvlgrlal 1507
Cdd:PRK03918  236 LKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEK------------------------ 291

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1508 lQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLtedkEKLVKEIESLKSskiaESTEWQEKHKELQKEYEILlqsye 1587
Cdd:PRK03918  292 -AEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI----EERIKELEEKEE----RLEELKKKLKELEKRLEEL----- 357

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1588 nvsneaeriqhvveavrQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSK-QQKILELEEENDRLRAE 1666
Cdd:PRK03918  358 -----------------EERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEiEEEISKITARIGELKKE 420

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1667 VhpagDTAKECMETLLSSNAS--------MKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLE 1738
Cdd:PRK03918  421 I----KELKKAIEELKKAKGKcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI 496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1739 ATEKHDNQTNVTEEGTQSIPGETEEQDslsmstrptcSESVPSAKSANPAVSKDFSShdeINNYLQQIDQLKERIAGLEE 1818
Cdd:PRK03918  497 KLKELAEQLKELEEKLKKYNLEELEKK----------AEEYEKLKEKLIKLKGEIKS---LKKELEKLEELKKKLAELEK 563

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1819 EKQKNKEFSQTLENEKNTL----LSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQL 1894
Cdd:PRK03918  564 KLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAE-TEKRL 642

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1895 AELNGSIGNYCQDVTDAQIKNelLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR--KEYLEKIQGAQKEPGNKSHAK 1972
Cdd:PRK03918  643 EELRKELEELEKKYSEEEYEE--LREEYLELSRELAGLRAELEELEKRREEIKKTLEklKEELEEREKAKKELEKLEKAL 720

                         650
                  ....*....|....*...
gi 530374448 1973 ELQELLKEKQQEVKQLQK 1990
Cdd:PRK03918  721 ERVEELREKVKKYKALLK 738
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1730-2146 6.26e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 49.13  E-value: 6.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1730 NVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTC-SESVPSAKSANPAVSKDFSSHDEINNYLQQIDQ 1808
Cdd:PLN02939   41 GFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELpQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSK 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1809 LKERIAGLEEEkqknkEFSQTLEN-EKNTLLsqistkdgelkmlqeevtkMNLLNQQIQEELSRVTKLKETAEEEKDDLE 1887
Cdd:PLN02939  121 DGEQLSDFQLE-----DLVGMIQNaEKNILL-------------------LNQARLQALEDLEKILTEKEALQGKINILE 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1888 ERLMNQLAELNGSignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEkiqgaqkepgn 1967
Cdd:PLN02939  177 MRLSETDARIKLA--------AQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENML----------- 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1968 kshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDL----EITKENLAQAVEhrkkaqaelaS 2043
Cdd:PLN02939  238 ---LKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVsklsPLQYDCWWEKVE----------N 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2044 FKVLLDDTQSE---AARVLADNLKLKKELQSNKESVKSQMKQKD-----EDLERRLEQAEEKHLKEKKNMQEKLDAlrre 2115
Cdd:PLN02939  305 LQDLLDRATNQvekAALVLDQNQDLRDKVDKLEASLKEANVSKFssykvELLQQKLKLLEERLQASDHEIHSYIQL---- 380

                         410       420       430
                  ....*....|....*....|....*....|...
gi 530374448 2116 kvhLEETIGEIQVTLNK--KDKEVQQLQENLDS 2146
Cdd:PLN02939  381 ---YQESIKEFQDTLSKlkEESKKRSLEHPADD 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1971-2189 6.45e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 6.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1971 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDD 2050
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2051 TQSEAARVLADNLKLkkelqSNKESVKSQMKQKD-EDLERR---LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEI 2126
Cdd:COG4942   102 QKEELAELLRALYRL-----GRQPPLALLLSPEDfLDAVRRlqyLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530374448 2127 QVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2189
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 157-405 6.64e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.18  E-value: 6.64e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  157 EELISTLQAQLTQAQAEQPAQSSTEMEefvmMKQQLQEKEEFISTLQAQLSQ--------------------TQAEQAAQ 216
Cdd:COG3096   835 EAELAALRQRRSELERELAQHRAQEQQ----LRQQLDQLKEQLQLLNKLLPQanlladetladrleelreelDAAQEAQA 910

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  217 KLRVLQRKLEEHEE---SLVGRAQVVDLLQQELTAAEQRNQILSQQLQQME-----AEHNTLRNTVETeREESKILLEKM 288
Cdd:COG3096   911 FIQQHGKALAQLEPlvaVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSevvqrRPHFSYEDAVGL-LGENSDLNEKL 989

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  289 E--LEVAERKLSfhNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKtshilslqktgQELQSACDALKDQN 366
Cdd:COG3096   990 RarLEQAEEARR--EAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQEL-----------EELGVQADAEAEER 1056

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 530374448  367 SKLLQDK-NEQAVQSAQTIQQLEDQLQQKSKEISQFLNRL 405
Cdd:COG3096  1057 ARIRRDElHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRL 1096
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 791-1033 7.97e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 48.39  E-value: 7.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  791 SEQSTLIRSLQSQ--LQNKESEVLEGAERVRHISSKVEELSQALSQ----KELEITKMDQLLLEKKRDVETLQQTIEEKD 864
Cdd:PRK05771   16 SYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDKlrsyLPKLNPLREEKKKVSVKSLEELIKDVEEEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  865 QQVTEISFSMTEKMVQLNEEKFSL-------------GVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSG-----LKQN 926
Cdd:PRK05771   96 EKIEKEIKELEEEISELENEIKELeqeierlepwgnfDLDLSLLLGFKYVSVFVGTVPEDKLEELKLESDVenveyISTD 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  927 YDEMSPAGQISKEELQHEFDLLKKENEQRKRklqaaLINRKELLQRVSRLEEELANLKDeskkeiplsetERGEVEED-- 1004
Cdd:PRK05771  176 KGYVYVVVVVLKELSDEVEEELKKLGFERLE-----LEEEGTPSELIREIKEELEEIEK-----------ERESLLEElk 239

                         250       260       270
                  ....*....|....*....|....*....|....*
gi 530374448 1005 KENKEYSEKCVTSKC------QEIEIYLKQTISEK 1033
Cdd:PRK05771  240 ELAKKYLEELLALYEyleielERAEALSKFLKTDK 274
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2265-2502 8.02e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 8.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2265 HSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMK 2344
Cdd:COG4942    16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2345 EQKIISLlsgKEEAIQVAIAELRQQHDKEIKELenLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLD 2424
Cdd:COG4942    96 RAELEAQ---KEELAELLRALYRLGRQPPLALL--LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELE 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530374448 2425 SFVKSMSSLQNDRdrivgdyQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYRE 2502
Cdd:COG4942   171 AERAELEALLAEL-------EEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
186-400 8.76e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 48.47  E-value: 8.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  186 VMMKQQLQEKEEFISTLQAQLSQtQAEQAAQKLRVLQRKLEEH--EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQM 263
Cdd:COG3206   160 AYLEQNLELRREEARKALEFLEE-QLPELRKELEEAEAALEEFrqKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEA 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  264 EAEHNTLRNTVETEREESKILLEKMELEVAERKLSfhNLQEEMHHLLEQF----EQAGQAQAELESRYSALEQKHKAEME 339
Cdd:COG3206   239 EARLAALRAQLGSGPDALPELLQSPVIQQLRAQLA--ELEAELAELSARYtpnhPDVIALRAQIAALRAQLQQEAQRILA 316

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530374448  340 EKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAV--QSAQTIQQLEDQLQQKSKEISQ 400
Cdd:COG3206   317 SLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRleREVEVARELYESLLQRLEEARL 379
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2560-3153 9.13e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 9.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2560 EKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGE 2639
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELT---------AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2640 IEdKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELD 2719
Cdd:TIGR02168  304 KQ-ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2720 ELKRKYdaslkelAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDsynqvqsfs 2799
Cdd:TIGR02168  383 TLRSKV-------AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELE--------- 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2800 KAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELH 2879
Cdd:TIGR02168  447 EELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLS 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2880 PLKAQLQEYQ-----------------DKTKAFQImQEELRQENLSWQH--ELHQLRMEKSSWEIHERRMK-EQYLMAIS 2939
Cdd:TIGR02168  527 ELISVDEGYEaaieaalggrlqavvveNLNAAKKA-IAFLKQNELGRVTflPLDSIKGTEIQGNDREILKNiEGFLGVAK 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2940 DKDQQLSHLQNLIRELRSSSS------QTQPLKVQYQRQASPET----SASPDGSQN----------LVYETEL--LRTQ 2997
Cdd:TIGR02168  606 DLVKFDPKLRKALSYLLGGVLvvddldNALELAKKLRPGYRIVTldgdLVRPGGVITggsaktnssiLERRREIeeLEEK 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2998 LNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAVSKEKgpLNID 3077
Cdd:TIGR02168  686 IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL--EAEI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  3078 VAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERD---------------------QRVAA 3136
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlrerleslerriaaterRLEDL 843

                          650
                   ....*....|....*..
gi 530374448  3137 ENALSVAEEQIRRLEHS 3153
Cdd:TIGR02168  844 EEQIEELSEDIESLAAE 860
mukB PRK04863
chromosome partition protein MukB;
196-400 9.52e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.41  E-value: 9.52e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  196 EEFISTLQAQLSQ--TQAEQAAQKLRVLQRKLEEHEESL---------VGRAQVVDLLQQELTAAEQRnQILSQQLQQME 264
Cdd:PRK04863  441 EDWLEEFQAKEQEatEELLSLEQKLSVAQAAHSQFEQAYqlvrkiageVSRSEAWDVARELLRRLREQ-RHLAEQLQQLR 519

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  265 AEHNTLRNTVETEREESKILLE-KMELEVAErkLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQkhkaEMEEKTS 343
Cdd:PRK04863  520 MRLSELEQRLRQQQRAERLLAEfCKRLGKNL--DDEDELEQLQEELEARLESLSESVSEARERRMALRQ----QLEQLQA 593

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 530374448  344 HILSLQKTGQELQSACDALKDqnsklLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 400
Cdd:PRK04863  594 RIQRLAARAPAWLAAQDALAR-----LREQSGEEFEDSQDVTEYMQQLLERERELTV 645
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 675-869 1.13e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  675 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELS-MVTELRAQVKQLEMNLAEAERQRRLDYESQTA 753
Cdd:COG4942    22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALArRIRALEQELAALEAELAELEKEIAELRAELEA 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  754 HDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS 833
Cdd:COG4942   102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 530374448  834 QKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTE 869
Cdd:COG4942   182 ELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
638-1089 1.19e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 1.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  638 AVPDIGQCHQDELERLKSQILELE-LNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLlsq 716
Cdd:PRK02224  177 GVERVLSDQRGSLDQLKAQIEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREEL--- 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  717 vkelsmvTELRAQVKQLEMNLAEAERQRR-LDYESQTAHDNLLT--EQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQ 793
Cdd:PRK02224  254 -------ETLEAEIEDLRETIAETEREREeLAEEVRDLRERLEEleEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  794 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV------ 867
Cdd:PRK02224  327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFgdapvd 406

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  868 ----TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK----EQVEEDNEVSSGLKQNYDEmspagqisKE 939
Cdd:PRK02224  407 lgnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVETIEEDRER--------VE 478

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  940 ELQHEFDLLKKENEQRKRKLQAAlINRKELLQRVSRLEEELANLKDeskkeipLSETERGEVEEDKEnkeysekcvtsKC 1019
Cdd:PRK02224  479 ELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEE-------LIAERRETIEEKRE-----------RA 539

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448 1020 QEieiyLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLL------QAEISENQAIIQKL 1089
Cdd:PRK02224  540 EE----LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLerirtlLAAIADAEDEIERL 611
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2249-2469 1.19e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.19e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2249 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQ 2328
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2329 ASRE-LTSRLHEEINMKEQKIISLLSGKEEAIQVA-----IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2402
Cdd:COG4942   101 AQKEeLAELLRALYRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530374448 2403 NQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAEN 2469
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1904-2641 1.28e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 47.81  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1904 YCQDVTDAQIK----NELLESEMKNLKKCVSELEEEKQQLVKEKTKVeSEIRKEYLEKIQGAQKEPGNKSH----AKELQ 1975
Cdd:pfam15921   83 YSHQVKDLQRRlnesNELHEKQKFYLRQSVIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHeleaAKCLK 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1976 E-LLKEKQQEVKQLQKDCIRYQEKISALERTVkaLEFVQTESQKdleITKENLAQAVEHRKKAQAelasFKVLLDDTQSE 2054
Cdd:pfam15921  162 EdMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL--VDFEEASGKK---IYEHDSMSTMHFRSLGSA----ISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2055 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2134
Cdd:pfam15921  233 ISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQN 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2135 KEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDeaKKWERKFSDAIQSKEEEIRLKEDNCSvLKDQLRQM--SIHME 2212
Cdd:pfam15921  313 SMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELE--KQLVLANSELTEARTERDQFSQESGN-LDDQLQKLlaDLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2213 ELKINISRlEHDKQIWESKAQTEVQLQ-------------QKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELK 2279
Cdd:pfam15921  390 EKELSLEK-EQNKRLWDRDTGNSITIDhlrrelddrnmevQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTA 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2280 SLKDQLTDLSNSLEKCKEQKGNLEgiirQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKE--- 2356
Cdd:pfam15921  469 QLESTKEMLRKVVEELTAKKMTLE----SSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDhlr 544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2357 ------EAIQVAIAE-------LRQQhdkeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL 2423
Cdd:pfam15921  545 nvqtecEALKLQMAEkdkvieiLRQQ----IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKI 620

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2424 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQE---AAAENNKLKEEI----RGLRSHMDDLNSENAKLDAE 2496
Cdd:pfam15921  621 RELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTTNKLKMQ 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2497 LIQYREDLNQVITIKDSQQK---QLLEVQLQQNKELENKYAKLEEKLKESEEANEDL---RRSFNALQEEKQDLSKEIES 2570
Cdd:pfam15921  701 LKSAQSELEQTRNTLKSMEGsdgHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMtnaNKEKHFLKEEKNKLSQELST 780

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530374448  2571 LKVSISQLTRQVTALQEEgtlglyHAQLKVK----EEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIE 2641
Cdd:pfam15921  781 VATEKNKMAGELEVLRSQ------ERRLKEKvanmEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQ 849
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1812-2348 1.31e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 48.15  E-value: 1.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1812 RIAGLEEEKQKNKEFSQT-LENEKNTLLSQIS-TKDGELKMLQEEVTKMNLLNQQIQ-EELSRVTKLKETAE----EEKD 1884
Cdd:COG5022   870 YLQSAQRVELAERQLQELkIDVKSISSLKLVNlELESEIIELKKSLSSDLIENLEFKtELIARLKKLLNNIDleegPSIE 949

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1885 DLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLE-------SEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK--EYL 1955
Cdd:COG5022   950 YVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVregnkanSELKNFKKELAELSKQYGALQESTKQLKELPVEvaELQ 1029

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1956 EKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEIT-KENLAQAVEHR 2034
Cdd:COG5022  1030 SASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLESTENLLKTINvKDLEVTNRNLV 1109

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2035 KKAQAE----LASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDeDLERRLEQAEEKHLKEKKNMQEK-L 2109
Cdd:COG5022  1110 KPANVLqfivAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELDGLFWEA-NLEALPSPPPFAALSEKRLYQSAlY 1188

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2110 DALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQ---SK 2186
Cdd:COG5022  1189 DEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSllnSI 1268

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2187 EEEIRLKEDNCSVLKDQLRQMSIHMEELKINisRLEHDKQIWESKAQTEVQLQQKVCDT--LQGENKEL---LSQLEETR 2261
Cdd:COG5022  1269 DNLLSSYKLEEEVLPATINSLLQYINVGLFN--ALRTKASSLRWKSATEVNYNSEELDDwcREFEISDVdeeLEELIQAV 1346

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2262 HLYHSSQNELAKLESELKSLKDQLTDLSNSLeKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEI 2341
Cdd:COG5022  1347 KVLQLLKDDLNKLDELLDACYSLNPAEIQNL-KSRYDPADKENNLPKEILKKIEALLIKQELQLSLEGKDETEVHLSEIF 1425


                  ....*..
gi 530374448 2342 NMKEQKI 2348
Cdd:COG5022  1426 SEEKSLI 1432
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
48-491 1.44e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.99  E-value: 1.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   48 EDVQERLAYAEQLVVELKDIIRQKDVQLQQKD-EALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGtvlptep 126
Cdd:COG4913   265 AAARERLAELEYLRAALRLWFAQRRLELLEAElEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG------- 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  127 QSEEQLSKhdkssteeemEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAqsstEMEEFVMMKQQLQEKEEFISTLQAQL 206
Cdd:COG4913   338 DRLEQLER----------EIERLERELEERERRRARLEALLAALGLPLPA----SAEEFAALRAEAAALLEALEEELEAL 403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  207 SQTQAEqAAQKLRVLQRKLEEHE---ESLVGR--------AQVVDLLQQELTAAEQRNQILSqQLQQMEAEHNTLRNTVE 275
Cdd:COG4913   404 EEALAE-AEAALRDLRRELRELEaeiASLERRksniparlLALRDALAEALGLDEAELPFVG-ELIEVRPEEERWRGAIE 481

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  276 T-----------EREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSH 344
Cdd:COG4913   482 RvlggfaltllvPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRFDY 561

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  345 IL------------SLQKTGQELQSACDALKD-------------QNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEIS 399
Cdd:COG4913   562 VCvdspeelrrhprAITRAGQVKGNGTRHEKDdrrrirsryvlgfDNRAKLAALEAELAELEEELAEAEERLEALEAELD 641

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  400 QFLNRlpLQQHETASQTSFPDVynegtqavteeNIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITllEAQN 479
Cdd:COG4913   642 ALQER--REALQRLAEYSWDEI-----------DVASAEREIAELEAELERLDASSDDLAALEEQLEELEAELE--ELEE 706

                         490
                  ....*....|..
gi 530374448  480 RTGEADREVSEI 491
Cdd:COG4913   707 ELDELKGEIGRL 718
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
664-916 1.46e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  664 FHKAQeiyeknldeKAKEISNLNQLIEEF-------KKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMN 736
Cdd:COG4913   197 LHKTQ---------SFKPIGDLDDFVREYmleepdtFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAA 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  737 LAEAERQRRLD-----YESQTAHDnLLTEQIHSLSIEakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV 811
Cdd:COG4913   268 RERLAELEYLRaalrlWFAQRRLE-LLEAELEELRAE-------LARLEAELERLEARLDALREELDELEAQIRGNGGDR 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  812 LEGAER--------VRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNE 883
Cdd:COG4913   340 LEQLEReierlereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRR 419

                         250       260       270
                  ....*....|....*....|....*....|...
gi 530374448  884 EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEED 916
Cdd:COG4913   420 ELRELEAEIASLERRKSNIPARLLALRDALAEA 452
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1951-2381 1.76e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1951 RKEYLEKIQGaQKEPGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERTVKALEFVQTESQKDLEITK--ENLA 2028
Cdd:COG4717    54 EADELFKPQG-RKPELNLKELKELEEELKEAEEKEEEYAEL----QEELEELEEELEELEAELEELREELEKLEklLQLL 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2029 QAVEHRKKAQAELASFKVLLDDTQSEAARVladnlklkKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEK 2108
Cdd:COG4717   129 PLYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2109 LDALRREKVHLEETIGEIQVTLNKKDKEVQQLQEN--------------------------------LDSTVTQLAAFTK 2156
Cdd:COG4717   201 LEELQQRLAELEEELEEAQEELEELEEELEQLENEleaaaleerlkearlllliaaallallglggsLLSLILTIAGVLF 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2157 SMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDN-CSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTE 2235
Cdd:COG4717   281 LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEElEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2236 VQLQQKVcdtLQGENKELLSQL----EETRHLYHSSQNELAKLESELKSLKDQLTdlsnslekckEQKGNLEGIIRQQEA 2311
Cdd:COG4717   361 EELQLEE---LEQEIAALLAEAgvedEEELRAALEQAEEYQELKEELEELEEQLE----------ELLGELEELLEALDE 427

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2312 DIQNSKfsYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEeaiqvaIAELRQQHDKEIKELENLL 2381
Cdd:COG4717   428 EELEEE--LEELEEELEELEEELEELREELAELEAELEQLEEDGE------LAELLQELEELKAELRELA 489
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
646-1009 2.01e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 2.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  646 HQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKEL-SMVT 724
Cdd:PRK02224  354 LEERAEELREEAAELESELEEARE----AVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELrEREA 429

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  725 ELRAQVKQLEMNLAEAERQRRLDYESQTAHDnlLTEQIHSLSIEakSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSqL 804
Cdd:PRK02224  430 ELEATLRTARERVEEAEALLEAGKCPECGQP--VEGSPHVETIE--EDRERVEELEAELEDLEEEVEEVEERLERAED-L 504

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  805 QNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDqlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEE 884
Cdd:PRK02224  505 VEAEDRIERLEERREDLEELIAERRETIEEKRERAEELR----ERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSK 580

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  885 KFSLGVEIKTLKEQLNLLSRAEEAKkEQVEEDNEVSSGLKQNYDEmspagqiSKEELQHEFD----LLKKENEQRKRKLQ 960
Cdd:PRK02224  581 LAELKERIESLERIRTLLAAIADAE-DEIERLREKREALAELNDE-------RRERLAEKRErkreLEAEFDEARIEEAR 652

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 530374448  961 AALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE 1009
Cdd:PRK02224  653 EDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERRE 701
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1432-1671 2.31e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 2.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1432 PEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEE 1511
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1512 RDKLITEMDRSLLENQSLSSScESLKLALEGltEDKEKLVKEIESLKSSkiaestewQEKHKELQKEYEILLQSYENVSN 1591
Cdd:COG4942    99 LEAQKEELAELLRALYRLGRQ-PPLALLLSP--EDFLDAVRRLQYLKYL--------APARREQAEELRADLAELAALRA 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1592 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAG 1671
Cdd:COG4942   168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
PTZ00121 PTZ00121
MAEBL; Provisional
 663-1207 2.61e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 2.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  663 NFHKAQEIYEKNLDEKAKEISNlnqlIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMV---TELRAQVKQLEMNLAE 739
Cdd:PTZ00121 1210 EERKAEEARKAEDAKKAEAVKK----AEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFArrqAAIKAEEARKADELKK 1285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  740 AERQRRLDyESQTAHDNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAE 816
Cdd:PTZ00121 1286 AEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  817 RvrhisSKVEELSQALSQKELEITKMDQlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlneekfslgvEIKTLK 896
Cdd:PTZ00121 1365 K-----AEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAKK------------KADEAK 1424

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  897 EQLNLLSRAEEAKKEQveEDNEVSSGLKQNYDEMSPAGQISKE-ELQHEFDLLKKENEQRKRKLQAalinrKELLQRVSR 975
Cdd:PTZ00121 1425 KKAEEKKKADEAKKKA--EEAKKADEAKKKAEEAKKAEEAKKKaEEAKKADEAKKKAEEAKKADEA-----KKKAEEAKK 1497

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  976 LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQfq 1055
Cdd:PTZ00121 1498 KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEED-- 1575

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1056 alvKQMNQTLQDKTNQIDllQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISppctGSSEHWKPELEEKILALEK 1135
Cdd:PTZ00121 1576 ---KNMALRKAEEAKKAE--EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK----AEEEKKKVEQLKKKEAEEK 1646

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530374448 1136 EKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1207
Cdd:PTZ00121 1647 KKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA 1718
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1808-2139 2.62e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 46.66  E-value: 2.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1808 QLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQIST-KDGELKMLQEEVTKMNLLNQQIQEELSRVTKlketaEEEKDDL 1886
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKaRQAEMDRQAAIYAEQERMAMERERELERIRQ-----EERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1887 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepg 1966
Cdd:pfam17380  363 ERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARK-VKILEEERQRKIQQQKVEMEQIRAEQEEARQ------- 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1967 nkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALErtvkalefvqtesQKDLEITKENLAQAVEHRKKAQAELASFKV 2046
Cdd:pfam17380  435 -----REVRRLEEERAREMERVRLEEQERQQQVERLR-------------QQEEERKRKKLELEKEKRDRKRAEEQRRKI 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2047 LLDDTQSEAARVLADNLK---LKKELQSNKESVKSQMKQKDEDLERRleqaEEKHLKEKKNMQEKLDALRREKVHLEETI 2123
Cdd:pfam17380  497 LEKELEERKQAMIEEERKrklLEKEMEERQKAIYEEERRREAEEERR----KQQEMEERRRIQEQMRKATEERSRLEAME 572

                          330
                   ....*....|....*.
gi 530374448  2124 GEIQVTLNKKDKEVQQ 2139
Cdd:pfam17380  573 REREMMRQIVESEKAR 588
PLN02939 PLN02939
transferase, transferring glycosyl groups
 590-957 3.03e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.82  E-value: 3.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  590 PNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDeleRLKSQILELelNFHKAQE 669
Cdd:PLN02939   40 RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHN---RASMQRDEA--IAAIDNE 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  670 IYEKNLDEKakEISNLNqlIEEFKKNADNNSSAFTALSEERDQLLSQV-KELSMVTELRAQVKQLEMNLAEAERQRRLDY 748
Cdd:PLN02939  115 QQTNSKDGE--QLSDFQ--LEDLVGMIQNAEKNILLLNQARLQALEDLeKILTEKEALQGKINILEMRLSETDARIKLAA 190

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  749 ESQtAHDNLLTEQI----HSLSIEAKSKDVKIEVLQNELDDVQlqfsEQSTLIRSLQSQLQNKESEVLEGAERV------ 818
Cdd:PLN02939  191 QEK-IHVEILEEQLeklrNELLIRGATEGLCVHSLSKELDVLK----EENMLLKDDIQFLKAELIEVAETEERVfkleke 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  819 -RHISSKVEELSQALSQKELEITKMDQLLLEKKRD-VETLQQTIEEKDQQVTEISFSMT-----EKMVQLNEEKFSLGVE 891
Cdd:PLN02939  266 rSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEkVENLQDLLDRATNQVEKAALVLDqnqdlRDKVDKLEASLKEANV 345

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448  892 IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEmspagqiSKEELQHEFDLLKKENEQRKR 957
Cdd:PLN02939  346 SKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQE-------SIKEFQDTLSKLKEESKKRSL 404
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 57-290 3.09e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 46.59  E-value: 3.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   57 AEQLVVELKDIIRQKDVQLQQKDEALQ------EERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEP-QSE 129
Cdd:PRK10929   25 EKQITQELEQAKAAKTPAQAEIVEALQsalnwlEERKGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVPPnMST 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  130 EQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEqpaqsstemeefvmMKQQLQEKEEFISTL------- 202
Cdd:PRK10929  105 DALEQEILQVSSQLLEKSRQAQQEQDRAREISDSLSQLPQQQTE--------------ARRQLNEIERRLQTLgtpntpl 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  203 -QAQLSQTQAEQAAQKLRVLQRKLeeheeslvgrAQVVDLLQQELtaAEQRNQILSQQLQQMEAEHNTLRNTVETER-EE 280
Cdd:PRK10929  171 aQAQLTALQAESAALKALVDELEL----------AQLSANNRQEL--ARLRSELAKKRSQQLDAYLQALRNQLNSQRqRE 238

                         250
                  ....*....|
gi 530374448  281 SKILLEKMEL 290
Cdd:PRK10929  239 AERALESTEL 248
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 241-478 3.75e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  241 LLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEkmELEVAERKLSfhNLQEEMHHLLEQFEQAGQAQ 320
Cdd:COG4942    10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLK--QLAALERRIA--ALARRIRALEQELAALEAEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  321 AELESRYSALEQKHKAEMEEKTSHILSLQKTGQelQSACDALkdqnskLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQ 400
Cdd:COG4942    86 AELEKEIAELRAELEAQKEELAELLRALYRLGR--QPPLALL------LSPEDFLDAVRRLQYLKYLAPARREQAEELRA 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530374448  401 FLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQ 478
Cdd:COG4942   158 DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1867-2383 5.22e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 5.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1867 EELSRVTKLKETAEEEKDDLE---------ERLMNQLAELNgsignYCQDVTD---AQIKNELLESEMKNLKKCVSELEE 1934
Cdd:COG4913   235 DDLERAHEALEDAREQIELLEpirelaeryAAARERLAELE-----YLRAALRlwfAQRRLELLEAELEELRAELARLEA 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1935 EKQQLVKEKTKVESEIR--KEYLEKIQGAQKEpgnkshakELQELLKEKQQEVKQLQKDCIRYQEKISALERTV----KA 2008
Cdd:COG4913   310 ELERLEARLDALREELDelEAQIRGNGGDRLE--------QLEREIERLERELEERERRRARLEALLAALGLPLpasaEE 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2009 LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDL- 2087
Cdd:COG4913   382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELp 461

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2088 -----------ERRLEQA--------------EEKHLK------EKKNMQEKLDALR-REKVHLEET--------IGEIQ 2127
Cdd:COG4913   462 fvgelievrpeEERWRGAiervlggfaltllvPPEHYAaalrwvNRLHLRGRLVYERvRTGLPDPERprldpdslAGKLD 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2128 VTLNKKDKEVQQ-LQENLD----STVTQLAAFTKSMSSL----QDDRDRVIDEAKKWERK----FS--DAIQSKEEEIRL 2192
Cdd:COG4913   542 FKPHPFRAWLEAeLGRRFDyvcvDSPEELRRHPRAITRAgqvkGNGTRHEKDDRRRIRSRyvlgFDnrAKLAALEAELAE 621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2193 KEDNCSVLKDQLRQMSIHMEELKINISRLEH-DKQIWESKAQTEVQLQqkvcdtlqgenkelLSQLEETRHLYHSSQNEL 2271
Cdd:COG4913   622 LEEELAEAEERLEALEAELDALQERREALQRlAEYSWDEIDVASAERE--------------IAELEAELERLDASSDDL 687

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2272 AKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLE--TDLQASRELTSRLHEEINMKEQKII 2349
Cdd:COG4913   688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEdlARLELRALLEERFAAALGDAVEREL 767

                         570       580       590
                  ....*....|....*....|....*....|....
gi 530374448 2350 SllsgkeEAIQVAIAELRQQHDKEIKELENLLSQ 2383
Cdd:COG4913   768 R------ENLEERIDALRARLNRAEEELERAMRA 795
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
937-1567 5.35e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 5.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  937 SKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLkDESKKEIPLSETERGEVEEDKENKEysekcvt 1016
Cdd:PRK03918  187 RTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEL-EELKEEIEELEKELESLEGSKRKLE------- 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1017 SKCQEIEIYLKQTISEKEvELQHIRKDLEEKLAAEEQFQALVKQMNQTLqDKTNQIDLLQAEISENQAIIQKLITSNTda 1096
Cdd:PRK03918  259 EKIRELEERIEELKKEIE-ELEEKVKELKELKEKAEEYIKLSEFYEEYL-DELREIEKRLSRLEEEINGIEERIKELE-- 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1097 sdgdsvalvketvvisppctgSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDY 1176
Cdd:PRK03918  335 ---------------------EKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKEL 393

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1177 NRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCsstPGLEEPLfkaTEQHhtqpvlESNLCPDWPSHS 1256
Cdd:PRK03918  394 EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKC---PVCGREL---TEEH------RKELLEEYTAEL 461

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1257 EDASAlqggtSVAQIKAQLKEIEAEKVELElKVSSTTSELTKKSEEVFQLQEQINK-QGLEIESLKTVSHEAEVHAESLQ 1335
Cdd:PRK03918  462 KRIEK-----ELKEIEEKERKLRKELRELE-KVLKKESELIKLKELAEQLKELEEKlKKYNLEELEKKAEEYEKLKEKLI 535

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1336 qKLESSQLQIAG-LEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEH 1414
Cdd:PRK03918  536 -KLKGEIKSLKKeLEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKEL 614

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1415 DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqaalisrkEALKENKSlQEELSLARGTIERLTKSLADVESQVSAQ 1494
Cdd:PRK03918  615 EREEKELKKLEEELDKAFEELAETEKRLEELRKEL--------EELEKKYS-EEEYEELREEYLELSRELAGLRAELEEL 685

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530374448 1495 NKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE 1567
Cdd:PRK03918  686 EKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEELTE 758
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 822-1071 6.25e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  822 SSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKFSLGVEIKTLKEQLNL 901
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL----ARRIRALEQELAALEAELAELEKEIAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  902 LSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELA 981
Cdd:COG4942    95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  982 NLKDESKKEiplsETERGEVEEDKENKEysekcvtskcqeieiylkQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQM 1061
Cdd:COG4942   175 ELEALLAEL----EEERAALEALKAERQ------------------KLLARLEKELAELAAELAELQQEAEELEALIARL 232

                         250
                  ....*....|
gi 530374448 1062 NQTLQDKTNQ 1071
Cdd:COG4942   233 EAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2642-2867 6.41e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2642 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDEL 2721
Cdd:COG4942    23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2722 KRKYDASLKELAQLKEQGLLNrerdALLSETAFsmnSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKA 2801
Cdd:COG4942   103 KEELAELLRALYRLGRQPPLA----LLLSPEDF---LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448 2802 MASLQNERDHLWNELEKFRKSEEGKQRSAAQpstspaEVQSLKKAMSSLQNDRDRLLKELKNLQQQ 2867
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIARLEAE 235
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2064-2649 6.67e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 6.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2064 KLKKELQSNKESVKSQMKQKDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVH-------LEETIGEIQVTLNKKD 2134
Cdd:PRK03918  193 ELIKEKEKELEEVLREINEISSELPELREELEklEKEVKELEELKEEIEELEKELESlegskrkLEEKIRELEERIEELK 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2135 KEVQQLQENLDStVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDaIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEEL 2214
Cdd:PRK03918  273 KEIEELEEKVKE-LKELKEKAEEYIKLSEFYEEYLDELREIEKRLSR-LEEEINGIEERIKELEEKEERLEELKKKLKEL 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2215 KINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyHSSQNELAKLESELKSLKDQLTDLSNSLEK 2294
Cdd:PRK03918  351 EKRLEELEERHELYE-------------------EAKAKKEELERLKK--RLTGLTPEKLEKELEELEKAKEEIEEEISK 409

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2295 CKEQKGNLEGIIRQQEADIQNSKFSYEQLETdlqASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRqqhdKEI 2374
Cdd:PRK03918  410 ITARIGELKKEIKELKKAIEELKKAKGKCPV---CGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLR----KEL 482

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2375 KELENLLSqeeeeNIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQldsfvksmsslqndrdrivgDYQQLEERhlSI 2454
Cdd:PRK03918  483 RELEKVLK-----KESELIKLKELAEQLKELEEKLKKYNLEELEKKAE--------------------EYEKLKEK--LI 535

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2455 ILEKDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQyredlnqvitiKDSQQKQLLEVQLQQNKELENKY 2533
Cdd:PRK03918  536 KLKGEIKsLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEE-----------LGFESVEELEERLKELEPFYNEY 604

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2534 AKLEEKLKESeeanEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEegtlglyhaqlKVKEEEVHRLSALFS 2613
Cdd:PRK03918  605 LELKDAEKEL----EREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEK-----------KYSEEEYEELREEYL 669

                         570       580       590
                  ....*....|....*....|....*....|....*....
gi 530374448 2614 SSQKRIAELEEELvcvqKEAAKKVGEIE---DKLKKELK 2649
Cdd:PRK03918  670 ELSRELAGLRAEL----EELEKRREEIKktlEKLKEELE 704
PRK12704 PRK12704
phosphodiesterase; Provisional
 2033-2195 6.76e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.15  E-value: 6.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2033 HRKKAQAELASFKVLLDDTQsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERR--LEQAEEKHLKEKKNMQEKLD 2110
Cdd:PRK12704   25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2111 ALRREKVHLEETIGEiqvtLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDD--RDRVIDEAK-KWERKFSDAIQSKE 2187
Cdd:PRK12704  104 LLEKREEELEKKEKE----LEQKQQELEKKEEELEELIEEQLQELERISGLTAEeaKEILLEKVEeEARHEAAVLIKEIE 179


                  ....*...
gi 530374448 2188 EEIRLKED 2195
Cdd:PRK12704  180 EEAKEEAD 187
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1332-1561 6.77e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 6.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1332 ESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALtkIQTEIIEQEDLIKALHTQLEmqa 1411
Cdd:COG4913   238 ERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELE--- 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1412 kEHDERIKQLQVELCEMKQKPEEIGeeSRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQV 1491
Cdd:COG4913   313 -RLEARLDALREELDELEAQIRGNG--GDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1492 SAqnkekdtvlgRLALLQEERDKLITEMDRsllenqslssscesLKLALEGLTEDKEKLVKEIESLKSSK 1561
Cdd:COG4913   390 AA----------LLEALEEELEALEEALAE--------------AEAALRDLRRELRELEAEIASLERRK 435
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1125-1610 6.78e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 6.78e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1125 ELEEKILALEKEKEQLQK---KLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1201
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDnieKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1202 IQVREsidgklpsTDQQESCSSTPGLEEPLFKATEQhhtqpvlesnlcpdwpshsedasalqggtsVAQIKAQLKEIEAE 1281
Cdd:TIGR04523  295 SEISD--------LNNQKEQDWNKELKSELKNQEKK------------------------------LEEIQNQISQNNKI 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1282 KVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTvsheaevHAESLQQKLESSQLQIaglehlRELQPKLDEL 1361
Cdd:TIGR04523  337 ISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK-------ENQSYKQEIKNLESQI------NDLESKIQNQ 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1362 QKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALH---TQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEE 1438
Cdd:TIGR04523  404 EKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTnqdSVKELIIKNLDNTRESLETQLKVLSRSINKIKQN 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1439 SRAKQQ---IQRKLQAALISRKEALKEN-KSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRL--ALLQEER 1512
Cdd:TIGR04523  484 LEQKQKelkSKEKELKKLNEEKKELEEKvKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELkkENLEKEI 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1513 DKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIES---LKSSKIAESTEWQEKHKELQKEYEILLQSYENV 1589
Cdd:TIGR04523  564 DEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEkekKISSLEKELEKAKKENEKLSSIIKNIKSKKNKL 643

                          490       500
                   ....*....|....*....|.
gi 530374448  1590 SNEAERIQHVVEAVRQEKQEL 1610
Cdd:TIGR04523  644 KQEVKQIKETIKEIRNKWPEI 664
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1269-1740 7.01e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 7.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1269 AQIKAQLKEIEAEKVELELK---VSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQI 1345
Cdd:PRK03918  203 EEVLREINEISSELPELREElekLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKV 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1346 AGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDlikalhtqLEMQAKEHDERIKQLQVEL 1425
Cdd:PRK03918  283 KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE--------KEERLEELKKKLKELEKRL 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1426 CEMKQKPEEIgEESRAKQQIQRKLQAALISR---------KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNK 1496
Cdd:PRK03918  355 EELEERHELY-EEAKAKKEELERLKKRLTGLtpeklekelEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKK 433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1497 EKDT--VLGRLaLLQEERDKLITEMDRSLLE-NQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTE------ 1567
Cdd:PRK03918  434 AKGKcpVCGRE-LTEEHRKELLEEYTAELKRiEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKeleekl 512

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1568 ---WQEKHKELQKEYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1641
Cdd:PRK03918  513 kkyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEkleELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE 592

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1642 MRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKEcMETLLSSNASMKEELERVKMEYETLSKKF-----QSLMSEKDSL 1716
Cdd:PRK03918  593 RLKELEPFYNEYLELKDAEKELEREEKELKKLEEE-LDKAFEELAETEKRLEELRKELEELEKKYseeeyEELREEYLEL 671

                         490       500
                  ....*....|....*....|....
gi 530374448 1717 SEEVQDLKHQIEGNVSKQANLEAT 1740
Cdd:PRK03918  672 SRELAGLRAELEELEKRREEIKKT 695
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1271-1738 7.20e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.40  E-value: 7.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1271 IKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKtvSHEAEVHAESLQQKLESSQlqiaglEH 1350
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN--NQKEQDWNKELKSELKNQE------KK 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1351 LRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQVELCEMKQ 1430
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNLESQINDLES 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1431 KPEEIGEESrakQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1510
Cdd:TIGR04523  399 KIQNQEKLN---QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1511 ERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKEL-QKEYEILLQSYENV 1589
Cdd:TIGR04523  476 SINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIsDLEDELNKDDFELK 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1590 SNEaeriqhvVEAVRQEKQELYGKLRSTEANKKETEKQlqeaeqemeemkekmrkfaksKQQKILELEEENDRLRAEVhp 1669
Cdd:TIGR04523  556 KEN-------LEKEIDEKNKEIEELKQTQKSLKKKQEE---------------------KQELIDQKEKEKKDLIKEI-- 605

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530374448  1670 agdtakecmETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLE 1738
Cdd:TIGR04523  606 ---------EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEII 665
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1020-1482 7.38e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 7.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1020 QEIEIYLKQTISEKEVELQHIrKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDG 1099
Cdd:COG4717    53 KEADELFKPQGRKPELNLKEL-KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLY 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1100 DSVALVKETVVISPPCtgssehwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRL 1179
Cdd:COG4717   132 QELEALEAELAELPER-------LEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1180 QEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQ--ESCSSTPGLEEPLFKATEQHHTQPVLESN---------- 1247
Cdd:COG4717   205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEErlKEARLLLLIAAALLALLGLGGSLLSLILTiagvlflvlg 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1248 -LCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKS-EEVFQLQEQINKQGLEIESLKtvsH 1325
Cdd:COG4717   285 lLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEElLELLDRIEELQELLREAEELE---E 361

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1326 EAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEdlikalHT 1405
Cdd:COG4717   362 ELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE------LE 435

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530374448 1406 QLEMQAKEHDERIKQLQVELCEMKQKPEEIgEESRAKQQIQRKLQAALISRKEALKENKSLQeelsLARGTIERLTK 1482
Cdd:COG4717   436 ELEEELEELEEELEELREELAELEAELEQL-EEDGELAELLQELEELKAELRELAEEWAALK----LALELLEEARE 507
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2064-2578 8.09e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 8.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2064 KLKKELQSNKESVKSQMKQKDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQ 2141
Cdd:PRK02224  199 KEEKDLHERLNGLESELAELDEEIERYEEQREqaRETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELA 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2142 EnldstvtQLAAFTKSMSSLQDDRDRVIDEAKkwerkFSDA-IQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISR 2220
Cdd:PRK02224  279 E-------EVRDLRERLEELEEERDDLLAEAG-----LDDAdAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAES 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2221 LEHDKQIWESKAqtevqlqqkvcDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLK-------DQLTDLSNSLE 2293
Cdd:PRK02224  347 LREDADDLEERA-----------EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRerfgdapVDLGNAEDFLE 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2294 KCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSrlheeinmkEQKIisllsgKEEAIQVAIAELRQQHDKE 2373
Cdd:PRK02224  416 ELREERDELREREAELEATLRTARERVEEAEALLEAGKCPEC---------GQPV------EGSPHVETIEEDRERVEEL 480

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2374 IKELENLLSQEEEENIVLEEEN--KKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERH 2451
Cdd:PRK02224  481 EAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2452 LSIILEKDQLIQEAAAENNKL---KEEIRGLRSHMDDLnSENAKLDAELIQYREDLNQVITIKDsQQKQLLEVQLQQNKE 2528
Cdd:PRK02224  561 AEAEEEAEEAREEVAELNSKLaelKERIESLERIRTLL-AAIADAEDEIERLREKREALAELND-ERRERLAEKRERKRE 638

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530374448 2529 LENKYAKLEEKLKESEEAN-----EDLRRSFNALQEEKQDLSKEIESLKVSISQL 2578
Cdd:PRK02224  639 LEAEFDEARIEEAREDKERaeeylEQVEEKLDELREERDDLQAEIGAVENELEEL 693
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1971-2495 8.23e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 8.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1971 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERtvkalefvqtesqkdleiTKENLAQAVEHRKKAQAELASFKVLLDD 2050
Cdd:PRK02224  201 EKDLHERLNGLESELAELDEEIERYEEQREQARE------------------TRDEADEVLEEHEERREELETLEAEIED 262

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2051 TQSEAARVladnlklKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK--EKKNMQEKLDALRREKVHLEETIGEIQV 2128
Cdd:PRK02224  263 LRETIAET-------EREREELAEEVRDLRERLEELEEERDDLLAEAGLDdaDAEAVEARREELEDRDEELRDRLEECRV 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2129 TLNKKDKEVQQLQENLDstvtQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMS 2208
Cdd:PRK02224  336 AAQAHNEEAESLREDAD----DLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2209 IHMEELKINISRLEhdkqiwESKAQTEVQLQQkVCDTLQgENKELLSQ---------LEETRHL--YHSSQNELAKLESE 2277
Cdd:PRK02224  412 DFLEELREERDELR------EREAELEATLRT-ARERVE-EAEALLEAgkcpecgqpVEGSPHVetIEEDRERVEELEAE 483

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2278 LKSLKDQLTDLSNSL-------------EKCKEQKGNLEGIIRQQEADIQNSKFSYEQ-------LETDLQASRELTSRL 2337
Cdd:PRK02224  484 LEDLEEEVEEVEERLeraedlveaedriERLEERREDLEELIAERRETIEEKRERAEElreraaeLEAEAEEKREAAAEA 563

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2338 HEEINMKEQKIISLlsgkeEAIQVAIAELRQQHDKeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENI 2417
Cdd:PRK02224  564 EEEAEEAREEVAEL-----NSKLAELKERIESLER-IRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKR 637

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530374448 2418 QQKAQLDSfvKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLkEEIRGLRSHMDDLNSENAKLDA 2495
Cdd:PRK02224  638 ELEAEFDE--ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL-EELEELRERREALENRVEALEA 712
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1273-1736 8.39e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 8.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1273 AQLKEIEAEKVELElkvsSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQiaglEHLR 1352
Cdd:COG4717    71 KELKELEEELKEAE----EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALE----AELA 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1353 ELQPKLDELQ---KLISKKEEDVSYLSGQLSEKEAALTKI--QTEIIEQEDLIKAL--HTQLEMQAKEHDERIKQLQVEL 1425
Cdd:COG4717   143 ELPERLEELEerlEELRELEEELEELEAELAELQEELEELleQLSLATEEELQDLAeeLEELQQRLAELEEELEEAQEEL 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1426 CEMKQKPEEIGEESRAKQQIQR----KLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKekdtv 1501
Cdd:COG4717   223 EELEEELEQLENELEAAALEERlkeaRLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREK----- 297

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1502 lgrlALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSS-KIAESTEWQEKHKELQKEYE 1580
Cdd:COG4717   298 ----ASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELlREAEELEEELQLEELEQEIA 373

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1581 ILLQSYeNVSNEAERIQHVVEAvrQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRkfAKSKQQKILELEEEN 1660
Cdd:COG4717   374 ALLAEA-GVEDEEELRAALEQA--EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE--LEELEEELEELEEEL 448

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530374448 1661 DRLRAEVhpagDTAKECMETLLSSN--ASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQAN 1736
Cdd:COG4717   449 EELREEL----AELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 757-988 9.30e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 9.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  757 LLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE 836
Cdd:COG4942    10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  837 LEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEI----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAE 906
Cdd:COG4942    90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  907 EAKKEQVEEDNEVSSGLKQNYDEMspagqisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE 986
Cdd:COG4942   170 EAERAELEALLAELEEERAALEAL-------KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242


                  ..
gi 530374448  987 SK 988
Cdd:COG4942   243 TP 244
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1409-1698 9.31e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.28  E-value: 9.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1409 MQAKEHDERIKQLQVE-LCEMKQKPEE-IGEESRAKQQIQRKLQAALiSRKEAL-KENKSLQEELSLARGTIERLTKSLA 1485
Cdd:PLN02939  116 QTNSKDGEQLSDFQLEdLVGMIQNAEKnILLLNQARLQALEDLEKIL-TEKEALqGKINILEMRLSETDARIKLAAQEKI 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1486 DVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKE---KLVKEIESLKSS-- 1560
Cdd:PLN02939  195 HVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEErvfKLEKERSLLDASlr 274

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1561 ----KIAESTEWQEKHKELQkeYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETekqlqeaeq 1633
Cdd:PLN02939  275 elesKFIVAQEDVSKLSPLQ--YDCWWEKVENLQDLLDRATNQVEkaaLVLDQNQDLRDKVDKLEASLKEA--------- 343

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530374448 1634 emeEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKME 1698
Cdd:PLN02939  344 ---NVSKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEESKKRSLE 405
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2249-2626 9.37e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 9.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2249 ENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFS--YEQLETD 2326
Cdd:COG4717    75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPerLEELEER 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2327 LQASREL---TSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHD---KEIKELENLLSQEEEENIVLEEeNKKAVD 2400
Cdd:COG4717   155 LEELRELeeeLEELEAELAELQEELEELLEQLSLATEEELQDLAEELEelqQRLAELEEELEEAQEELEELEE-ELEQLE 233

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2401 KTNQLMETLKTIKKENIQQKA------------QLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAE 2468
Cdd:COG4717   234 NELEAAALEERLKEARLLLLIaaallallglggSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2469 NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKElenkyakleEKLKESEEANE 2548
Cdd:COG4717   314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA---------ALLAEAGVEDE 384

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530374448 2549 DLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEEL 2626
Cdd:COG4717   385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAEL 462
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1294-1726 1.02e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1294 SELTKKSEEVFQLQEQINKQGL-EIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEedv 1372
Cdd:COG4717    49 ERLEKEADELFKPQGRKPELNLkELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL--- 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1373 sylsgQLSEKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQLQVELCEMKQKPEEIGEESRAkqQIQRKLQAA 1452
Cdd:COG4717   126 -----QLLPLYQELEALEAELAELPERLEELEERLE-ELRELEEELEELEAELAELQEELEELLEQLSL--ATEEELQDL 197

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1453 LISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDT--------VLGRLALLQEERDKLITEMDRSLL 1524
Cdd:COG4717   198 AEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLkearllllIAAALLALLGLGGSLLSLILTIAG 277

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1525 ENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVR 1604
Cdd:COG4717   278 VLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1605 QEKQELygklrsteaNKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLlsS 1684
Cdd:COG4717   358 ELEEEL---------QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL--D 426

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 530374448 1685 NASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQ 1726
Cdd:COG4717   427 EEELEEELEELEEELEELEEELEELREELAELEAELEQLEED 468
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1780-2015 1.05e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.92  E-value: 1.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1780 PSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNK-----EFSQTLENEKNTLLSQISTKDGELKMLQEE 1854
Cdd:PRK05771   36 LKEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEELEKIEKEIKELEEEISELENE 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1855 VTKmnllnqqIQEELSRVTKLKETAEEEKDDLEERLMNQLAelnGSI--GNYCQDVTDAQIKNELLESEMKN-------- 1924
Cdd:PRK05771  116 IKE-------LEQEIERLEPWGNFDLDLSLLLGFKYVSVFV---GTVpeDKLEELKLESDVENVEYISTDKGyvyvvvvv 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1925 LKKCVSELEEE--KQQLVKEKTKVE---SEIRKEYLEKIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQ--- 1996
Cdd:PRK05771  186 LKELSDEVEEElkKLGFERLELEEEgtpSELIREIKEELEEIEKE------RESLLEELKELAKKYLEELLALYEYLeie 259

                         250       260
                  ....*....|....*....|
gi 530374448 1997 -EKISALERTVKALEFVQTE 2015
Cdd:PRK05771  260 lERAEALSKFLKTDKTFAIE 279
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2855-3150 1.07e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2855 DRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKE-- 2932
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRErl 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2933 -----QYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASpetsaspdgsqnlvyETELLRTQLNDSLKEIHQ 3007
Cdd:TIGR02168  312 anlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA---------------ELEELEAELEELESRLEE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  3008 KELRIQQLNSNFSQLLEEKNTLSIQLcdtsQSLRENQQHygdllnhcavLEKQVQELQavskekgplnidvapgapQEKN 3087
Cdd:TIGR02168  377 LEEQLETLRSKVAQLELQIASLNNEI----ERLEARLER----------LEDRRERLQ------------------QEIE 424

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530374448  3088 GVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRL 3150
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
647-1079 1.07e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 1.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  647 QDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADN-------NSSAFTALSEERDQLLSQVKE 719
Cdd:PRK02224  250 REELETLEAEIEDLRETIAET----EREREELAEEVRDLRERLEELEEERDDllaeaglDDADAEAVEARREELEDRDEE 325

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  720 L-SMVTELRAQVKQLEmNLAEAERQRRLDYESQTAHdnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 798
Cdd:PRK02224  326 LrDRLEECRVAAQAHN-EEAESLREDADDLEERAEE---LREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFG 401

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  799 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKK-----RDVE--TLQQTIEEKDQQVTEis 871
Cdd:PRK02224  402 DAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEgsPHVETIEEDRERVEE-- 479

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  872 fsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK--EQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLK 949
Cdd:PRK02224  480 ---------LEAELEDLEEEVEEVEERLERAEDLVEAEDriERLEERREDLEELIAERRETIEEKRERAEELRERAAELE 550

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  950 KENEQRKRKLQAALINRKELLQRVSRLEEELANLKD--ESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLK 1027
Cdd:PRK02224  551 AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKEriESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLA 630

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530374448 1028 QT---ISEKEVELQHIRkdLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEI 1079
Cdd:PRK02224  631 EKrerKRELEAEFDEAR--IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEI 683
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 48-343 1.15e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 1.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448    48 EDVQERLAYAEQLVVELKDIIR---QKDVQLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPT 124
Cdd:TIGR02169  691 SSLQSELRRIENRLDELSQELSdasRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   125 EPQ-SEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLtqAQAEQPAQSSTEMEEFvmMKQQLQEKEEFISTLQ 203
Cdd:TIGR02169  771 EEDlHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARL--REIEQKLNRLTLEKEY--LEKEIQELQEQRIDLK 846

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   204 AQLSQTQAEQAAQKLRV--LQRKLEEH-------EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTV 274
Cdd:TIGR02169  847 EQIKSIEKEIENLNGKKeeLEEELEELeaalrdlESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530374448   275 ETEREESKILLE--KMELEVAERKLSFHNLQEEMHHLLEQFEQAG-------QAQAELESRYSALEQKHKAEMEEKTS 343
Cdd:TIGR02169  927 EALEEELSEIEDpkGEDEEIPEEELSLEDVQAELQRVEEEIRALEpvnmlaiQEYEEVLKRLDELKEKRAKLEEERKA 1004
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1540-1952 1.20e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1540 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEillqSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1619
Cdd:COG4717    48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEE----EYAELQEELEELEEELEELEAELEELREELEKLEK 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1620 NKKETEKQLQEAEQEMEEMKEKMR-KFAKSKQQKILELEEENDRLRAEVHpagDTAKECMETLLSSNASMKEELERVKME 1698
Cdd:COG4717   124 LLQLLPLYQELEALEAELAELPERlEELEERLEELRELEEELEELEAELA---ELQEELEELLEQLSLATEEELQDLAEE 200

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1699 YETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTN----------VTEEGTQSIPGETEEQDSLS 1768
Cdd:COG4717   201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaallaLLGLGGSLLSLILTIAGVLF 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1769 MSTRPTCSESVPSAKSANPAVSK----DFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLEnEKNTLLSQISTK 1844
Cdd:COG4717   281 LVLGLLALLFLLLAREKASLGKEaeelQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIE-ELQELLREAEEL 359

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1845 DGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER--LMNQLAELNGSIGNYCQDVTDAQIKNELLESEM 1922
Cdd:COG4717   360 EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELeeLEEQLEELLGELEELLEALDEEELEEELEELEE 439

                         410       420       430
                  ....*....|....*....|....*....|
gi 530374448 1923 KnlkkcVSELEEEKQQLVKEKTKVESEIRK 1952
Cdd:COG4717   440 E-----LEELEEELEELREELAELEAELEQ 464
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1978-2189 1.28e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1978 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAAR 2057
Cdd:COG3883    18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2058 VLADNLKLKKELQS-------NKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTL 2130
Cdd:COG3883    98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 530374448 2131 NKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEE 2189
Cdd:COG3883   178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
46 PHA02562
endonuclease subunit; Provisional
 1809-2098 1.33e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.23  E-value: 1.33e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1809 LKERIAGLEEEkqknkefSQTLENEKNTLLSQISTKdgelKMLQEEVTKMNllNQQIQEELSRVTKLKETAEEEKDDLEE 1888
Cdd:PHA02562  172 NKDKIRELNQQ-------IQTLDMKIDHIQQQIKTY----NKNIEEQRKKN--GENIARKQNKYDELVEEAKTIKAEIEE 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1889 rLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEE------KQQLVKEKTKVESeirkeylekiqgaq 1962
Cdd:PHA02562  239 -LTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITK-------------- 303

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1963 kepgNKSHAKELQ---ELLKEKQQEVKQLqkdciryqeKISALERTVKALEFvqtesQKDLEITKENLAQAVEHRKKAQA 2039
Cdd:PHA02562  304 ----IKDKLKELQhslEKLDTAIDELEEI---------MDEFNEQSKKLLEL-----KNKISTNKQSLITLVDKAKKVKA 365

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 530374448 2040 ELAsfkvllddtqseaarvladnlKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKH 2098
Cdd:PHA02562  366 AIE---------------------ELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKY 403
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2764-3052 1.61e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 44.16  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2764 LSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQpstspaevqsL 2843
Cdd:COG1196   231 LLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR----------L 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2844 KKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELhplKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSW 2923
Cdd:COG1196   301 EQDIARLEERRRELEERLEELEEELAELEEELEEL---EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEA 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2924 EIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPdgsqnlvyETELLRTQLNDSLK 3003
Cdd:COG1196   378 EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE--------EEEEEEEALEEAAE 449

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 530374448 3004 EIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLN 3052
Cdd:COG1196   450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2230-2439 1.89e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2230 SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQ 2309
Cdd:COG4942    30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2310 EADIQ-NSKFSYEQL----ETDLQASRELtsRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQE 2384
Cdd:COG4942   110 LRALYrLGRQPPLALllspEDFLDAVRRL--QYLKYLAPARREQAEELRADLAELAALRAELEAER-AELEALLAELEEE 186

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530374448 2385 EEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDR 2439
Cdd:COG4942   187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2407-2625 1.91e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2407 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsiILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2486
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR----IAALARRIRALEQELAALEAELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2487 NSENAKLDAELIQ-----YREDLNQVITIKDSQQ------------KQLLEVQLQQNKELENKYAKLEEKLKESEEANED 2549
Cdd:COG4942    96 RAELEAQKEELAEllralYRLGRQPPLALLLSPEdfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448 2550 LRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhAQLKVKEEEVHRLSALFSSSQKRIAELEEE 2625
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEKELAELA---------AELAELQQEAEELEALIARLEAEAAAAAER 242
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 156-885 1.91e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 44.27  E-value: 1.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   156 KEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEefistlqAQLSQTQAEQAAQKLRVLQRKLEEHEESLVGR 235
Cdd:TIGR00606  366 RDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDE-------AKTAAQLCADLQSKERLKQEQADEIRDEKKGL 438

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   236 AQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNtlrntvetereesKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQ 315
Cdd:TIGR00606  439 GRTIELKKEILEKKQEELKFVIKELQQLEGSSD-------------RILELDQELRKAERELSKAEKNSLTETLKKEVKS 505

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   316 AGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELqSACDALKDQNSKLLQDKNEQAVQSAQTiQQLEDQLQQKS 395
Cdd:TIGR00606  506 LQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKM-DKDEQIRKIKSRHSDELTSLLGYFPNK-KQLEDWLHSKS 583

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   396 KEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEE---------NIASLQKRVVELENEKGALLLSSIELEELKAENE 466
Cdd:TIGR00606  584 KEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQlssyedklfDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATA 663

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   467 KLSSQITLLEAQN--------RTGEADREVSEIsIVDIANKRSSSAEEsgQDVLENTFSQKHKELSVLLL-------EMK 531
Cdd:TIGR00606  664 VYSQFITQLTDENqsccpvcqRVFQTEAELQEF-ISDLQSKLRLAPDK--LKSTESELKKKEKRRDEMLGlapgrqsIID 740

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   532 EAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTGqdfpLMPNEESSLPAVEKEqasTEHQSR 611
Cdd:TIGR00606  741 LKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVT----IMERFQMELKDVERK---IAQQAA 813

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   612 TSEEISLNDAGVELKSTKQDGDKSLSAVPDIG--------------QCHQDELERLKSQILELELNFHKAQEiYEKNLDE 677
Cdd:TIGR00606  814 KLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIelnrkliqdqqeqiQHLKSKTNELKSEKLQIGTNLQRRQQ-FEEQLVE 892

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   678 KAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQ---------------------------V 730
Cdd:TIGR00606  893 LSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNdikekvknihgymkdienkiqdgkddyL 972

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   731 KQLEMNLA-----------------EAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQ 793
Cdd:TIGR00606  973 KQKETELNtvnaqleecekhqekinEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQMQVLQM 1052

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   794 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKmdqlllEKKRDVETLQQTIEEKDQQVTEISFS 873
Cdd:TIGR00606 1053 KQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAE------EKYREMMIVMRTTELVNKDLDIYYKT 1126

                          810
                   ....*....|..
gi 530374448   874 MTEKMVQLNEEK 885
Cdd:TIGR00606 1127 LDQAIMKFHSMK 1138
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1026-1210 2.03e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1026 LKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL---ITSNTDASDGDSV 1102
Cdd:COG4942    32 LQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELraeLEAQKEELAELLR 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1103 ALVKETVVISPPCTGSSEHWK-------------PELEEKILALEKEKEQLQkKLQEALTSRKAILKKAQEKERHLREEL 1169
Cdd:COG4942   112 ALYRLGRQPPLALLLSPEDFLdavrrlqylkylaPARREQAEELRADLAELA-ALRAELEAERAELEALLAELEEERAAL 190

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 530374448 1170 KQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1210
Cdd:COG4942   191 EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
152-566 2.03e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 2.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  152 KLQEKEELISTLQAQLTQAQAEQPAQSSTEmeefvmmkQQLQEKEEFISTLQAQLSQTQAEQAAQKLRVLQRKLEEHEES 231
Cdd:COG4717    72 ELKELEEELKEAEEKEEEYAELQEELEELE--------EELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAE 143

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  232 LVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESkilLEKMELEVAERKLSFHNLQEEMHHLLE 311
Cdd:COG4717   144 LPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEE---LQDLAEELEELQQRLAELEEELEEAQE 220

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  312 QFEQAGQAQAELESRYSALEQKHKAEMEE--------------KTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQA 377
Cdd:COG4717   221 ELEELEEELEQLENELEAAALEERLKEARlllliaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  378 VQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQ-TSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALllssi 456
Cdd:COG4717   301 GKEAEELQALPALEELEEEELEELLAALGLPPDLSPEElLELLDRIEELQELLREAEELEEELQLEELEQEIAAL----- 375

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  457 eLEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEE 536
Cdd:COG4717   376 -LAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREE 454

                         410       420       430
                  ....*....|....*....|....*....|
gi 530374448  537 IAFLKLQLQGKRAEEADHEVLDQKEMKQME 566
Cdd:COG4717   455 LAELEAELEQLEEDGELAELLQELEELKAE 484
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1457-2225 2.10e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.19  E-value: 2.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1457 KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESL 1536
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1537 KLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRS 1616
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1617 TEAN----KKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTaKECMETLLSSNASMKEEL 1692
Cdd:pfam02463  336 EIEElekeLKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEE-LELKSEEEKEAQLLLELA 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1693 ERVKMEYETLSKK-------------FQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHdnqtNVTEEGTQSIPG 1759
Cdd:pfam02463  415 RQLEDLLKEEKKEeleileeeeesieLKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ----LVKLQEQLELLL 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1760 ETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLS 1839
Cdd:pfam02463  491 SRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRAL 570

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1840 QISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLK------ETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQI 1913
Cdd:pfam02463  571 TELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQldkatlEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRK 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1914 KNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCI 1993
Cdd:pfam02463  651 GVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEA 730

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1994 RYQEKISALERTVKALEFVQTEsqkDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNK 2073
Cdd:pfam02463  731 QDKINEELKLLKQKIDEEEEEE---EKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2074 ESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeiqvTLNKKDKEVQQLQENLDSTVTQLAA 2153
Cdd:pfam02463  808 EELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELE-----RLEEEITKEELLQELLLKEEELEEQ 882

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530374448  2154 FTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDK 2225
Cdd:pfam02463  883 KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENN 954
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1297-1724 2.13e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.95  E-value: 2.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1297 TKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAE-SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYL 1375
Cdd:pfam15921  408 TGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAK 487

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1376 SGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelcEMKQKpeeiGEESRAKQQIQRKLQAALIS 1455
Cdd:pfam15921  488 KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ----HLKNE----GDHLRNVQTECEALKLQMAE 559

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1456 RKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLlenqslsSSCES 1535
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARV-------SDLEL 632

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1536 LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLR 1615
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1616 STEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHpagdtakecmeTLLSSNASMKEELERV 1695
Cdd:pfam15921  713 NTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKH-----------FLKEEKNKLSQELSTV 781

                          410       420
                   ....*....|....*....|....*....
gi 530374448  1696 KMEYETLSKKFQSLMSEKDSLSEEVQDLK 1724
Cdd:pfam15921  782 ATEKNKMAGELEVLRSQERRLKEKVANME 810
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1275-1742 2.21e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.90  E-value: 2.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1275 LKEIEAEKVELElkvssttsELTKKSEEVfqlQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLREl 1354
Cdd:PRK03918  171 IKEIKRRIERLE--------KFIKRTENI---EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE- 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1355 qpKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALhTQLEMQAKEH-------------------- 1414
Cdd:PRK03918  239 --EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKAEEYiklsefyeeyldelreiekr 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1415 ----DERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLqAALISRKEALKENKSLQEEL-----SLARGTIERLTKSLA 1485
Cdd:PRK03918  316 lsrlEEEINGIEERIKELEEKEERLEELKKKLKELEKRL-EELEERHELYEEAKAKKEELerlkkRLTGLTPEKLEKELE 394

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1486 DVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRsllenqsLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIA-E 1564
Cdd:PRK03918  395 ELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEkE 467

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1565 STEWQEKHKELQKEyeilLQSYENVSNEAERIQHVVEAVRQEKqELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRK 1644
Cdd:PRK03918  468 LKEIEEKERKLRKE----LRELEKVLKKESELIKLKELAEQLK-ELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIK 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1645 FAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLK 1724
Cdd:PRK03918  543 SLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELK 622

                         490
                  ....*....|....*...
gi 530374448 1725 HQIEGNVSKQANLEATEK 1742
Cdd:PRK03918  623 KLEEELDKAFEELAETEK 640
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1804-2043 2.49e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1804 QQIDQLKERIAGLEEE----KQKNKEFSqtLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRvtKLKETA 1879
Cdd:COG3206   182 EQLPELRKELEEAEAAleefRQKNGLVD--LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGS--GPDALP 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1880 EEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQiknelleSEMKNLKkcvSELEEEKQQLVKEKTKVESEIRKEYLekiq 1959
Cdd:COG3206   258 ELLQSPVIQQLRAQLAELEAELAELSARYTPNH-------PDVIALR---AQIAALRAQLQQEAQRILASLEAELE---- 323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1960 gaqkepGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERtvkalefvqtesqkDLEITKENLAQAVEHRKKAQA 2039
Cdd:COG3206   324 ------ALQAREASLQAQLAQLEARLAELPEL----EAELRRLER--------------EVEVARELYESLLQRLEEARL 379


                  ....
gi 530374448 2040 ELAS 2043
Cdd:COG3206   380 AEAL 383
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2660-2887 2.54e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2660 NETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQg 2739
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE- 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2740 lLNRERDALlsetafsmnsteENSLSHLEKLNQQllsKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKF 2819
Cdd:COG4942    99 -LEAQKEEL------------AELLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530374448 2820 RKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKEL----KNLQQQYLQINQEITELHPLKAQLQE 2887
Cdd:COG4942   163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLekelAELAAELAELQQEAEELEALIARLEA 234
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1797-2030 2.82e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 2.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1797 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKmnlLNQQIQEelsRVTKLK 1876
Cdd:COG3883    16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAE---AEAEIEE---RREELG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1877 ETAEEEKddLEERLMNQLAELNGSignycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEirkeyLE 1956
Cdd:COG3883    90 ERARALY--RSGGSVSYLDVLLGS-----ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAK-----LA 157

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530374448 1957 KIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2030
Cdd:COG3883   158 ELEALKAE--LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 796-1199 2.91e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 2.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   796 LIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKM------DQLLLEKKRDVETLQQTIEEKDQQVTE 869
Cdd:pfam05483  364 LLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELkkilaeDEKLLDEKKQFEKIAEELKGKEQELIF 443

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   870 ISFSMTEKMVQLNEEKFSLGV-EIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLL 948
Cdd:pfam05483  444 LLQAREKEIHDLEIQLTAIKTsEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDII 523

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   949 --KKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYL 1026
Cdd:pfam05483  524 ncKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQI 603

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1027 KQTISEKEvELQHIRKDLEEKLAAEE--------QFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASd 1098
Cdd:pfam05483  604 ENKNKNIE-ELHQENKALKKKGSAENkqlnayeiKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAK- 681

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1099 gdsvALVKETVVISPPCTGSSEHwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKER---HLREELKQQKDD 1175
Cdd:pfam05483  682 ----AIADEAVKLQKEIDKRCQH---KIAEMVALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSakaALEIELSNIKAE 754

                          410       420
                   ....*....|....*....|....
gi 530374448  1176 YNRLQEQFDEQSKENENIGDQLRQ 1199
Cdd:pfam05483  755 LLSLKKQLEIEKEEKEKLKMEAKE 778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 76-329 2.94e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   76 QQKDEALQEERKAADNKIKKlklhakakltsLNKYIEEMKAQggtvlptEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQE 155
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAE-----------LEKELAALKKE-------EKALLKQLAALERRIAALARRIRALEQELAA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  156 KEELISTLQAQLTQAQAEQPAQSstemEEFVMMKQQLQeKEEFISTLQAQLSQTQAEQAAQKLRVLQRKLEEHEEslvgR 235
Cdd:COG4942    81 LEAELAELEKEIAELRAELEAQK----EELAELLRALY-RLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----Q 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  236 AQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQ 315
Cdd:COG4942   152 AEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231

                         250
                  ....*....|....
gi 530374448  316 AGQAQAELESRYSA 329
Cdd:COG4942   232 LEAEAAAAAERTPA 245
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2367-2584 3.02e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2367 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDY-- 2444
Cdd:COG4942    29 LEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELae 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2445 -----QQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdaeliqyrEDLNQVITIKDSQQKQLL 2519
Cdd:COG4942   109 llralYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELEALL 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530374448 2520 EVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTA 2584
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 422-1209 3.14e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 3.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   422 YNEGTQAVTEENIASLQKRVVELENEKGALLLS----SIELEELKAENEKLSSQITLLEAQNrtGEADREVSEIsivdia 497
Cdd:TIGR02168  215 YKELKAELRELELALLVLRLEELREELEELQEElkeaEEELEELTAELQELEEKLEELRLEV--SELEEEIEEL------ 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   498 nkrsssaeesgQDVLENTfSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEgiapikmkv 577
Cdd:TIGR02168  287 -----------QKELYAL-ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEK--------- 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   578 fLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTsEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQI 657
Cdd:TIGR02168  346 -LEELKEELESLEAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   658 LELELNFHKAQ-EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMN 736
Cdd:TIGR02168  424 EELLKKLEEAElKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   737 LAEAERQRRLDYESQTAHDNLLTEQIH-----SLSIEA----KSKDVKIEVLQNELDDVQLQFSEQS------------- 794
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILGVLSELISvdegyEAAIEAalggRLQAVVVENLNAAKKAIAFLKQNELgrvtflpldsikg 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   795 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRdvETLQQTIEEKDQQVTEISFSM 874
Cdd:TIGR02168  584 TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKK--LRPGYRIVTLDGDLVRPGGVI 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   875 TEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEdnevSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQ 954
Cdd:TIGR02168  662 TGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAE----LRKELEELEEELEQLRKELEELSRQISALRKDLAR 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   955 RKRKLQAalinrkeLLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIyLKQTISEKE 1034
Cdd:TIGR02168  738 LEAEVEQ-------LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA-LREALDELR 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1035 VELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPP 1114
Cdd:TIGR02168  810 AELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1115 CTGSSEhwKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIG 1194
Cdd:TIGR02168  890 ALLRSE--LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDE 967

                          810
                   ....*....|....*
gi 530374448  1195 DQLRQLQIQVRESID 1209
Cdd:TIGR02168  968 EEARRRLKRLENKIK 982
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2071-2683 3.15e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.29  E-value: 3.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2071 SNKESVKSQMKQKDEDLERRLEqaEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQvTLNKKDKEVQQLQENLDSTV-T 2149
Cdd:pfam12128  207 EDDGVVPPKSRLNRQQVEHWIR--DIQAIAGIMKIRPEFTKLQQEFNTLESAELRLS-HLHFGYKSDETLIASRQEERqE 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2150 QLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKD-----------QLRQMSIHMEELKINI 2218
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDadietaaadqeQLPSWQSELENLEERL 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2219 SRLEHDKQIWESKAQTEVQLQQKVC-DTLQGENKELLSQLEETRHLYHSSQNELAKLESELKS-LKDQLTDLSNSLEKCK 2296
Cdd:pfam12128  364 KALTGKHQDVTAKYNRRRSKIKEQNnRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREqLEAGKLEFNEEEYRLK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2297 EQKGNLEGIIRQQEADiqnskfsyEQLETDLQASRELTSRLHEEINMKEQKIisllsgkeEAIQVAIAELRQQHDKEIKE 2376
Cdd:pfam12128  444 SRLGELKLRLNQATAT--------PELLLQLENFDERIERAREEQEAANAEV--------ERLQSELRQARKRRDQASEA 507

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2377 LENLLSQEEEENIVLEEENKKAVDKTNQLMETLKtikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHL-SII 2455
Cdd:pfam12128  508 LRQASRRLEERQSALDELELQLFPQAGTLLHFLR---KEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLyGVK 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2456 LEKDQL-IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYredlnqvitikdsqqkqllevqlqqNKELENKYA 2534
Cdd:pfam12128  585 LDLKRIdVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQA-------------------------NGELEKASR 639

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2535 KLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLK----VSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLS- 2609
Cdd:pfam12128  640 EETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKdsanERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAy 719

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448  2610 --ALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDagimrnetetaEERVAELARDLVEMEQKL 2683
Cdd:pfam12128  720 wqVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVD-----------PDVIAKLKREIRTLERKI 784
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 624-1200 3.26e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 43.50  E-value: 3.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   624 ELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAqeIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAF 703
Cdd:TIGR01612 1119 DIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLL 1196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   704 TALSE-ERDQL-LSQVKELSMVTELRAQVKQLEmNLAEAERQRRLDYESQTAH----DNLLTEQIHSLSIEAKSKDVK-- 775
Cdd:TIGR01612 1197 NEIAEiEKDKTsLEEVKGINLSYGKNLGKLFLE-KIDEEKKKSEHMIKAMEAYiedlDEIKEKSPEIENEMGIEMDIKae 1275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   776 IEVLQNELDDVQLQFSEQSTLIRSLqSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVET 855
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNI 1354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   856 LQ-QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLlsRAEEAKKEQVEEDNEVSsGLKQNYDEMSPAG 934
Cdd:TIGR01612 1355 LKlNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINL--EECKSKIESTLDDKDID-ECIKKIKELKNHI 1431

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   935 QISKEELQHEFDLLKKENEQrkrklqaALINRKELLQRVSRLEEELANLKDESKKEIPLSetergeVEEDKENKEYSEKC 1014
Cdd:TIGR01612 1432 LSEESNIDTYFKNADENNEN-------VLLLFKNIEMADNKSQHILKIKKDNATNDHDFN------INELKEHIDKSKGC 1498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1015 VTskcqEIEIYLKQTISEKEVELQHiRKDLEE------KLAAEEQFQALVKQMNQTL---QDKTNQIdLLQAEISENQ-- 1083
Cdd:TIGR01612 1499 KD----EADKNAKAIEKNKELFEQY-KKDVTEllnkysALAIKNKFAKTKKDSEIIIkeiKDAHKKF-ILEAEKSEQKik 1572

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1084 AIIQKLITSNTDASDGD--SVALVKETVVISPpctgssehwkpeLEEKILALEkekeQLQKKLQEALTSRKAILKKAQEK 1161
Cdd:TIGR01612 1573 EIKKEKFRIEDDAAKNDksNKAAIDIQLSLEN------------FENKFLKIS----DIKKKINDCLKETESIEKKISSF 1636

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 530374448  1162 ERHLRE-ELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1200
Cdd:TIGR01612 1637 SIDSQDtELKENGDNLNSLQEFLESLKDQKKNIEDKKKEL 1676
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2269-2894 3.30e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 3.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2269 NELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKI 2348
Cdd:TIGR04523   40 KKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQK 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2349 ISLlsgkeeaiqvaiaelrqqhDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVK 2428
Cdd:TIGR04523  120 NKL-------------------EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEK 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2429 SMSSLQNDRDRIVGDYQQLEERhLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVI 2508
Cdd:TIGR04523  181 EKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLK 259

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2509 TIKDSQQKQLLEVQLQQNKElenkyakleeklkeseeanedlrrsfnalQEEKQDLSKEIESLKVSISQLTRQvtalQEE 2588
Cdd:TIGR04523  260 DEQNKIKKQLSEKQKELEQN-----------------------------NKKIKELEKQLNQLKSEISDLNNQ----KEQ 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2589 GTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEiEDKLKKELKHLHHDAGIMRNETETAEER 2668
Cdd:TIGR04523  307 DWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESE-NSEKQRELEEKQNEIEKLKKENQSYKQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2669 VAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLK-EQGLLNRERDA 2747
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKElIIKNLDNTRES 465

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2748 L---LSETAFSMNSTEENslshLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNEL-------- 2816
Cdd:TIGR04523  466 LetqLKVLSRSINKIKQN----LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKkekeskis 541

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2817 ---EKFRKSEEGKQRSA--AQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDK 2891
Cdd:TIGR04523  542 dleDELNKDDFELKKENleKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEK 621


                   ...
gi 530374448  2892 TKA 2894
Cdd:TIGR04523  622 AKK 624
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1125-1201 3.39e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 3.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1125 ELEEKILALEKEKEQLQKKLQEALTSRKAILKK----AQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1200
Cdd:COG0542   415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDelaeLEEELEALKARWEAEKELIEEIQELKEELEQRYGKIPELEKEL 494


                  .
gi 530374448 1201 Q 1201
Cdd:COG0542   495 A 495
COG5022 COG5022
Myosin heavy chain [General function prediction only];
1921-2353 3.53e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 43.14  E-value: 3.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1921 EMKNLKKCVSEL--EEEKQQLVKEKTKVESEIRKEYLekIQGAQKEPGNKSHAKEL--QELLKEKQQEVKQLQKDCIRYQ 1996
Cdd:COG5022   811 EYRSYLACIIKLqkTIKREKKLRETEEVEFSLKAEVL--IQKFGRSLKAKKRFSLLkkETIYLQSAQRVELAERQLQELK 888

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1997 E---KISALERTVKALEFVQTESQKDLEitkENLAQAVEHRKKAQAELasfKVLLDDTQSEaarvladnlklkkeLQSNK 2073
Cdd:COG5022   889 IdvkSISSLKLVNLELESEIIELKKSLS---SDLIENLEFKTELIARL---KKLLNNIDLE--------------EGPSI 948

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2074 ESVKSQMKQKDEDLERRLEQAEEkhlkEKKNMQEKLDALRREkvhleetigeiqvtLNKKDKEVQQLQENLDSTVTQLAA 2153
Cdd:COG5022   949 EYVKLPELNKLHEVESKLKETSE----EYEDLLKKSTILVRE--------------GNKANSELKNFKKELAELSKQYGA 1010

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2154 FTKSMSSLQDdRDRVIDEAKKWERKFSDaiQSKEEEIRLKEDNC-SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKA 2232
Cdd:COG5022  1011 LQESTKQLKE-LPVEVAELQSASKIISS--ESTELSILKPLQKLkGLLLLENNQLQARYKALKLRRENSLLDDKQLYQLE 1087

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2233 QTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESElKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQ---- 2308
Cdd:COG5022  1088 STENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEIS-KFLSQLVNTLEPVFQKLSVLQLELDGLFWEanle 1166

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*
gi 530374448 2309 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLS 2353
Cdd:COG5022  1167 ALPSPPPFAALSEKRLYQSALYDEKSKLSSSEVNDLKNELIALFS 1211
PRK09039 PRK09039
peptidoglycan -binding protein;
2657-2791 3.73e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.65  E-value: 3.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2657 IMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLK 2736
Cdd:PRK09039   43 FLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELA 122

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530374448 2737 EQglLNRERDalLSETAfsmnsteensLSHLEKLNQQLLSKDEQLLHLSSQLEDS 2791
Cdd:PRK09039  123 QE--LDSEKQ--VSARA----------LAQVELLNQQIAALRRQLAALEAALDAS 163
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
41-478 3.74e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 3.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   41 EFNNTTQEDVQERLAYAEQLVVELKDIIRQKDvQLQQKDEALQEERKAADNKIKKLKLHAKAKLtslnkyIEEMKAQGGT 120
Cdd:COG4717    67 ELNLKELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQLLP------LYQELEALEA 139

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  121 VLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEK----E 196
Cdd:COG4717   140 ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEEleeaQ 219

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  197 EFISTLQAQLSQTQAEQAAQKlrvLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQI-------------LSQQLQQM 263
Cdd:COG4717   220 EELEELEEELEQLENELEAAA---LEERLKEARLLLLIAAALLALLGLGGSLLSLILTIagvlflvlgllalLFLLLARE 296

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  264 EAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRysaleqkhkaemeEKTS 343
Cdd:COG4717   297 KASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL-------------EEEL 363

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  344 HILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTsfpdvyN 423
Cdd:COG4717   364 QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEE------L 437

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530374448  424 EGTQAVTEENIASLQKRVVELENEKGAlLLSSIELEELKAENEKLSSQITLLEAQ 478
Cdd:COG4717   438 EEELEELEEELEELREELAELEAELEQ-LEEDGELAELLQELEELKAELRELAEE 491
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1878-2109 3.76e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 3.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1878 TAEEEKDDLEERLMN----QLAELNGSIGNYcqdvtdaqiKNELLESEMKNLKKCVSELEEEKQqlvKEKTKVESEIRKE 1953
Cdd:PRK05771   13 TLKSYKDEVLEALHElgvvHIEDLKEELSNE---------RLRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1954 YLEKIQGAQKEPGNKShakELQELLKEKQQEVKQLQKDCIRYQEKISALE---------------RTVKA---------- 2008
Cdd:PRK05771   81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELENEIKELEQEIERLEpwgnfdldlslllgfKYVSVfvgtvpedkl 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2009 LEFVQTESQKDLEITKEN-------LAQAVEHRKKAQAELASFKVLLDDTQSE--AARVLADNLKLKKELQSNKESVKSQ 2079
Cdd:PRK05771  158 EELKLESDVENVEYISTDkgyvyvvVVVLKELSDEVEEELKKLGFERLELEEEgtPSELIREIKEELEEIEKERESLLEE 237

                         250       260       270
                  ....*....|....*....|....*....|..
gi 530374448 2080 MKQKDEDLERRLEQAEEK--HLKEKKNMQEKL 2109
Cdd:PRK05771  238 LKELAKKYLEELLALYEYleIELERAEALSKF 269
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 653-1444 3.98e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 3.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   653 LKSQILELELNFHKAQEIYEKNLDEkAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQ 732
Cdd:TIGR00606  222 IRDQITSKEAQLESSREIVKSYENE-LDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTD 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   733 LEMNLAEAERQRRLDYESQTAHDnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV- 811
Cdd:TIGR00606  301 EQLNDLYHNHQRTVREKERELVD--CQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLe 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   812 LEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQtieekdQQVTEISFSMTEKMVQLNEEKFSLGVE 891
Cdd:TIGR00606  379 LDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQ------EQADEIRDEKKGLGRTIELKKEILEKK 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   892 IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQ--NYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINR-KE 968
Cdd:TIGR00606  453 QEELKFVIKELQQLEGSSDRILELDQELRKAERElsKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHhTT 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   969 LLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIY------LKQTISEKEVELQHIRK 1042
Cdd:TIGR00606  533 TRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTrdrlakLNKELASLEQNKNHINN 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1043 DLEEKLAAEEQFQALVKQMNQTlQDKTNQIDLLQAEIsENQAIIQKLITSNTDASDGDSVALVKETVVISPPC------T 1116
Cdd:TIGR00606  613 ELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEI-EKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCqrvfqtE 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1117 GSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQ 1196
Cdd:TIGR00606  691 AELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQ 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1197 LRQLqiqvrESIDGKLPSTdqqESCSSTPGLEEPLFKATEQHHTQpvlesnlcpdWPSHSEDASALQGGTSVAQIKAQLK 1276
Cdd:TIGR00606  771 ETLL-----GTIMPEEESA---KVCLTDVTIMERFQMELKDVERK----------IAQQAAKLQGSDLDRTVQQVNQEKQ 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1277 EIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRE-LQ 1355
Cdd:TIGR00606  833 EKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEqDS 912

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1356 PKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTE----IIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1431
Cdd:TIGR00606  913 PLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKvkniHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKH 992

                          810
                   ....*....|...
gi 530374448  1432 PEEIGEESRAKQQ 1444
Cdd:TIGR00606  993 QEKINEDMRLMRQ 1005
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1344-1525 4.03e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 4.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1344 QIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQV 1423
Cdd:COG1579     5 DLRALLDLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIK----RLELEIEEVEARIKKYEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1424 ELcEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTvlg 1503
Cdd:COG1579    81 QL-GNVRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEA--- 156

                         170       180
                  ....*....|....*....|..
gi 530374448 1504 RLALLQEERDKLITEMDRSLLE 1525
Cdd:COG1579   157 ELEELEAEREELAAKIPPELLA 178
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
152-340 4.08e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 4.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  152 KLQEKEELISTLQAQLTQAQAE-----QPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQtqAEQAAQKLRVLQRKLE 226
Cdd:COG4913   618 ELAELEEELAEAEERLEALEAEldalqERREALQRLAEYSWDEIDVASAEREIAELEAELER--LDASSDDLAALEEQLE 695

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  227 EHEESLvgraqvvDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVEtereeskillEKMELEVAERKLSFhnlqEEM 306
Cdd:COG4913   696 ELEAEL-------EELEEELDELKGEIGRLEKELEQAEEELDELQDRLE----------AAEDLARLELRALL----EER 754

                         170       180       190
                  ....*....|....*....|....*....|....
gi 530374448  307 HHLLEQFEQAGQAQAELESRYSALEQKHKAEMEE 340
Cdd:COG4913   755 FAAALGDAVERELRENLEERIDALRARLNRAEEE 788
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
240-497 4.11e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 4.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  240 DLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSfhnlqeemhHLLEQFEQAGQA 319
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLS---------ELESQLAEARAE 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  320 QAELESRYSALEQKHKAEMEEKTSHILS--LQKTGQELQSAcDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKE 397
Cdd:COG3206   235 LAEAEARLAALRAQLGSGPDALPELLQSpvIQQLRAQLAEL-EAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQR 313

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  398 ISQFLnrlplqqhetasqtsfpdvynEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEklSSQITLLEA 477
Cdd:COG3206   314 ILASL---------------------EAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVE--VARELYESL 370

                         250       260
                  ....*....|....*....|....
gi 530374448  478 QNRTGEAD----REVSEISIVDIA 497
Cdd:COG3206   371 LQRLEEARlaeaLTVGNVRVIDPA 394
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2548-2958 4.17e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 4.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2548 EDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQeegtlglyhaqlkvKEEEVHRLSALFSSSQKRIAELEEELv 2627
Cdd:COG4717    84 EEKEEEYAELQEELEELEEELEELEAELEELREELEKLE--------------KLLQLLPLYQELEALEAELAELPERL- 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2628 cvqkeaakkvgeieDKLKKELKHLHHdagiMRNETETAEERVAELARDLVEMEQKLLMVTKEnkgltaQIQSFGRSMSSL 2707
Cdd:COG4717   149 --------------EELEERLEELRE----LEEELEELEAELAELQEELEELLEQLSLATEE------ELQDLAEELEEL 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2708 QNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQ 2787
Cdd:COG4717   205 QQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLG 284

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2788 LEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSE--EGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQ 2865
Cdd:COG4717   285 LLALLFLLLAREKASLGKEAEELQALPALEELEEEEleELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ 364

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2866 QQYLQINQE----------ITELHPLKAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYL 2935
Cdd:COG4717   365 LEELEQEIAallaeagvedEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEEL 444

                         410       420
                  ....*....|....*....|....
gi 530374448 2936 MA-ISDKDQQLSHLQNLIRELRSS 2958
Cdd:COG4717   445 EEeLEELREELAELEAELEQLEED 468
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1259-1452 4.18e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 4.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1259 ASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLeieslktvsheaevhaeslqQKL 1338
Cdd:COG4913   281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGG--------------------DRL 340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1339 ESSQLQIAGLE-HLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDER 1417
Cdd:COG4913   341 EQLEREIERLErELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 530374448 1418 IKQLQVELCEMKQKPEEIGEES-RAKQQIQRKLQAA 1452
Cdd:COG4913   421 LRELEAEIASLERRKSNIPARLlALRDALAEALGLD 456
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2247-2878 4.39e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 42.97  E-value: 4.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2247 QGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLegiiRQQEADIQNSKFSYEQLETD 2326
Cdd:PRK01156  137 QGEMDSLISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKL----KSSNLELENIKKQIADDEKS 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2327 LQASRELTSRLHEEINMKEQKIISLLSGKEEAIqvAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLM 2406
Cdd:PRK01156  213 HSITLKEIERLSIEYNNAMDDYNNLKSALNELS--SLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPV 290

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2407 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDrdrivgdyqqleerhlsiiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2486
Cdd:PRK01156  291 YKNRNYINDYFKYKNDIENKKQILSNIDAE-------------------INKYHAIIKKLSVLQKDYNDYIKKKSRYDDL 351

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2487 NSENAKLDAELIQYREDLNQVITIKDSQQkqllevqlQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSK 2566
Cdd:PRK01156  352 NNQILELEGYEMDYNSYLKSIESLKKKIE--------EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISS 423

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2567 EIESLKVSISQLTRQVTALQEEGTLGLYHAQLKV-----KEEEVHRLSALFSSSQKRiaeLEEELVCVQKEAAKkvgeIE 2641
Cdd:PRK01156  424 KVSSLNQRIRALRENLDELSRNMEMLNGQSVCPVcgttlGEEKSNHIINHYNEKKSR---LEEKIREIEIEVKD----ID 496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2642 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVtKENKGLTAQIQSFGRSMsslqnsrdhaneELDEL 2721
Cdd:PRK01156  497 EKIVDLKKRKEYLESEEINKSINEYNKIESARADLEDIKIKINEL-KDKHDKYEEIKNRYKSL------------KLEDL 563

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2722 KRKYDASLKELAQLKEQGLLN-----RERDALLSETAFSMNSTEENsLSHLEKLNQQLLSKDEQLLHLssqLEDSYNQVQ 2796
Cdd:PRK01156  564 DSKRTSWLNALAVISLIDIETnrsrsNEIKKQLNDLESRLQEIEIG-FPDDKSYIDKSIREIENEANN---LNNKYNEIQ 639

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2797 SFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEIT 2876
Cdd:PRK01156  640 ENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRIN 719


                  ..
gi 530374448 2877 EL 2878
Cdd:PRK01156  720 DI 721
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 673-1210 4.44e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.70  E-value: 4.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   673 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELsmvtelRAQVKQLEMNLAEAERQRrLDYESQT 752
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDL------KKQKEELENELNLLEKEK-LNIQKNI 189

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   753 AHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQAL 832
Cdd:TIGR04523  190 DKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   833 SQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKF---------------SLGVEIKTLKE 897
Cdd:TIGR04523  270 SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLeeiqnqisqnnkiisQLNEQISQLKK 349

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   898 QLNLLSRAEEAKKEQVEEDNEVSSGLK---QNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS 974
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKkenQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   975 RLEEELANLKDESKkeiplsetergeveeDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQF 1054
Cdd:TIGR04523  430 RLKETIIKNNSEIK---------------DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK 494

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1055 QALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKL----ITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEE-- 1128
Cdd:TIGR04523  495 EKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLesekKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEElk 574

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1129 -KILALEKEKEQLQKKLQEALTSRKAILKKAQEKERhLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1207
Cdd:TIGR04523  575 qTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEK-KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653


                   ...
gi 530374448  1208 IDG 1210
Cdd:TIGR04523  654 IKE 656
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1267-1467 4.51e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.70  E-value: 4.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1267 SVAQIKAQLKEIEAEKVELELKVSS--TTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQ 1344
Cdd:COG3206   176 ALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA 255

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1345 IAGLEHLRELQPKLDELQKLISKKEEdvsyLSGQLSEKEAALTKIQTEIIEQEDLIKA----LHTQLEMQAKEHDERIKQ 1420
Cdd:COG3206   256 LPELLQSPVIQQLRAQLAELEAELAE----LSARYTPNHPDVIALRAQIAALRAQLQQeaqrILASLEAELEALQAREAS 331

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 530374448 1421 LQVELCEMKQKPEEIGEESRAKQQIQRKLQAA------LISRKEALKENKSLQ 1467
Cdd:COG3206   332 LQAQLAQLEARLAELPELEAELRRLEREVEVArelyesLLQRLEEARLAEALT 384
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1415-1667 5.32e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.61  E-value: 5.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1415 DERIKQLQ----VELCEMKQkpEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGT-----IERLTKSLA 1485
Cdd:PRK05771   19 DEVLEALHelgvVHIEDLKE--ELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVKsleelIKDVEEELE 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1486 DVESQVSAQNKEkdtvlgrLALLQEERDKLITEMDR-SLLENQSLS----SSCESLKLALEGLTEDKEKLVKEIESLKSS 1560
Cdd:PRK05771   97 KIEKEIKELEEE-------ISELENEIKELEQEIERlEPWGNFDLDlsllLGFKYVSVFVGTVPEDKLEELKLESDVENV 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1561 KIAESTEwqEK-------HKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELygklrstEANKKETEKQLqeaeq 1633
Cdd:PRK05771  170 EYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL-------EEIEKERESLL----- 235

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 530374448 1634 emeemkEKMRKFAKSKQQKILELEE--ENDRLRAEV 1667
Cdd:PRK05771  236 ------EELKELAKKYLEELLALYEylEIELERAEA 265
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2479-2681 5.39e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 5.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2479 LRSHMDDLNSENAKLDAELIQYREDLNQvitikdsqqkqlLEVQLQQNKElENKYAKLEEKLKESEEANEDLRRSFNALQ 2558
Cdd:COG3206   166 LELRREEARKALEFLEEQLPELRKELEE------------AEAALEEFRQ-KNGLVDLSEEAKLLLQQLSELESQLAEAR 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2559 EEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVG 2638
Cdd:COG3206   233 AELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 530374448 2639 EIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQ 2681
Cdd:COG3206   313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
PTZ00121 PTZ00121
MAEBL; Provisional
 1935-2474 5.63e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 5.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1935 EKQQLVKEKTKVESEIRKEylEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQT 2014
Cdd:PTZ00121 1221 EDAKKAEAVKKAEEAKKDA--EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKA 1298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2015 ESQKDLEITK----------ENLAQAVEHRKKAQA--ELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ 2082
Cdd:PTZ00121 1299 EEKKKADEAKkkaeeakkadEAKKKAEEAKKKADAakKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKK 1378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2083 KDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEiqvTLNKKDKEVQQLQEnLDSTVTQLAAFTKSMSSLQ 2162
Cdd:PTZ00121 1379 KADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKAD---EAKKKAEEKKKADE-AKKKAEEAKKADEAKKKAE 1454

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2163 DDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDncsvLKDQLRQMSIHMEELKiniSRLEHDKQIWESKAQTEVQLQQKV 2242
Cdd:PTZ00121 1455 EAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE----AKKKAEEAKKKADEAK---KAAEAKKKADEAKKAEEAKKADEA 1527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2243 CDTLQGENKELLSQLEETRhlyhsSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQ 2322
Cdd:PTZ00121 1528 KKAEEAKKADEAKKAEEKK-----KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE 1602

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2323 LETDLQASReltSRLHEEINMKEQKIisllsGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2402
Cdd:PTZ00121 1603 EEKKMKAEE---AKKAEEAKIKAEEL-----KKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530374448 2403 NQLMETLKT--IKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2474
Cdd:PTZ00121 1675 KKAEEAKKAeeDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2184-2944 5.95e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.73  E-value: 5.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2184 QSKEEEIRLKEDNCSVLKDQLRQMsihmEELKINISRLEHDKQIWESkaqTEVQLQQKVCDTLQGENKELLSQLEETRHL 2263
Cdd:TIGR00606  234 ESSREIVKSYENELDPLKNRLKEI----EHNLSKIMKLDNEIKALKS---RKKQMEKDNSELELKMEKVFQGTDEQLNDL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2264 YHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEgiIRQQEADIQNSKFSYEQLETDLQAsreLTSRLHEEINM 2343
Cdd:TIGR00606  307 YHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELL--VEQGRLQLQADRHQEHIRARDSLI---QSLATRLELDG 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2344 KEQKIISllsgkEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL 2423
Cdd:TIGR00606  382 FERGPFS-----ERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEEL 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2424 DSFVKSMSSLQNDRDRIVGDYQQL--EERHLSIiLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE----- 2496
Cdd:TIGR00606  457 KFVIKELQQLEGSSDRILELDQELrkAERELSK-AEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtttrt 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2497 ----LIQYREDLNQVITIKDSQQKQLLEVQL---QQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIE 2569
Cdd:TIGR00606  536 qmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELE 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2570 SLKVSISQLTRQV----TALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKeAAKKVGEIEDKLK 2645
Cdd:TIGR00606  616 SKEEQLSSYEDKLfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCP-VCQRVFQTEAELQ 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2646 KELKHLHHDAGIMRNETETAEERVAELARD------LVEMEQKLL-MVTKENKGLTAQIQSFGRSMSSLQNSRDHANEEL 2718
Cdd:TIGR00606  695 EFISDLQSKLRLAPDKLKSTESELKKKEKRrdemlgLAPGRQSIIdLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL 774

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2719 D------ELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEEnslshLEKLNQQLLSKDEQLLHLSSQLEDSY 2792
Cdd:TIGR00606  775 GtimpeeESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRT-----VQQVNQEKQEKQHELDTVVSKIELNR 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2793 NQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ-I 2871
Cdd:TIGR00606  850 KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEElI 929

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2872 NQEITELHPLKAQLQEYQDKTKA--------FQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQ 2943
Cdd:TIGR00606  930 SSKETSNKKAQDKVNDIKEKVKNihgymkdiENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDT 1009


                   .
gi 530374448  2944 Q 2944
Cdd:TIGR00606 1010 Q 1010
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 152-805 5.96e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.41  E-value: 5.96e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   152 KLQEKEELISTLQAQLTQAQAEQPAQssteMEEFVMMKQQLQEKEEFISTLQAQLSQTQA-------EQAAQK--LRVLQ 222
Cdd:pfam15921  420 ELDDRNMEVQRLEALLKAMKSECQGQ----MERQMAAIQGKNESLEKVSSLTAQLESTKEmlrkvveELTAKKmtLESSE 495

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   223 RKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNtVETEreeskilLEKMELEVAERKLSFHNL 302
Cdd:pfam15921  496 RTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRN-VQTE-------CEALKLQMAEKDKVIEIL 567

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   303 QEEMHHLLEQFEQAGQAQAELESRYSALEQK-HKAEMEEKTSHILSLQKTGQ--ELQSACDALKDQNSKLLQDKNEQaVQ 379
Cdd:pfam15921  568 RQQIENMTQLVGQHGRTAGAMQVEKAQLEKEiNDRRLELQEFKILKDKKDAKirELEARVSDLELEKVKLVNAGSER-LR 646

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   380 SAQTIQQLEDQLQQKSKEISQFLNRLPlQQHETASQtsfpDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELE 459
Cdd:pfam15921  647 AVKDIKQERDQLLNEVKTSRNELNSLS-EDYEVLKR----NFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGS 721

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   460 ELKAENEK--LSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQ--DVLENTFSQKHK---ELSVLLLEMKE 532
Cdd:pfam15921  722 DGHAMKVAmgMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKlsQELSTVATEKNKmagELEVLRSQERR 801

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   533 AQEEIAFLKLQLQGKRAEEADHEVLDQKE--------------MKQMEGEG-IAPIKMKVFLEDTGQdfplMPNEESSLP 597
Cdd:pfam15921  802 LKEKVANMEVALDKASLQFAECQDIIQRQeqesvrlklqhtldVKELQGPGyTSNSSMKPRLLQPAS----FTRTHSNVP 877

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   598 AVEKEQASTEHQSRTSEEISlNDAGVELKSTKQDGDKSLSAVPDIGQCHQDEL----------ERLKSQILELELNFHKA 667
Cdd:pfam15921  878 SSQSTASFLSHHSRKTNALK-EDPTRDLKQLLQELRSVINEEPTVQLSKAEDKgrapslgaldDRVRDCIIESSLRSDIC 956

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   668 QEIYEKNLDEKAKEISNLN-QLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRL 746
Cdd:pfam15921  957 HSSSNSLQTEGSKSSETCSrEPVLLHAGELEDPSSCFTFPSTASPSVKNSASRSFHSSPKKSPVHSLLTSSAEGSIGSSS 1036

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530374448   747 DYES-QTAHDNLLTEQIHSLSIEAKSKDVK-----IEVLQNELDDVQLQFSEQSTLIRSLQSQLQ 805
Cdd:pfam15921 1037 QYRSaKTIHSPDSVKDSQSLPIETTGKTCRklqnrLESLQTLVEDLQLKNQAMSSMIRNQEKRIQ 1101
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1022-1201 5.97e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 5.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1022 IEIYLKQTISEK-----------EVELQHIRKDLEEKLAAEEQFQA---------LVKQMNQTLQDKTNQIDLLQAEISE 1081
Cdd:COG3206   158 AEAYLEQNLELRreearkaleflEEQLPELRKELEEAEAALEEFRQknglvdlseEAKLLLQQLSELESQLAEARAELAE 237

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1082 NQAIIQKLitSNTDASDGDSVALVKETVVISppctgssehwkpELEEKILALEKEKEQ--------------LQKKLQEA 1147
Cdd:COG3206   238 AEARLAAL--RAQLGSGPDALPELLQSPVIQ------------QLRAQLAELEAELAElsarytpnhpdviaLRAQIAAL 303

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 530374448 1148 LTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1201
Cdd:COG3206   304 RAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
46 PHA02562
endonuclease subunit; Provisional
 2502-2738 6.14e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 6.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2502 EDL--NQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQD----LSKEIESLKVSI 2575
Cdd:PHA02562  157 EDLldISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKTIKAEI 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2576 SQLTRQVTALQEEGtlGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVC------------VQKEAAKKVGEIEDK 2643
Cdd:PHA02562  237 EELTDELLNLVMDI--EDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCptctqqisegpdRITKIKDKLKELQHS 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2644 LKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQsfgrsmsSLQNSRDHANEELDELKR 2723
Cdd:PHA02562  315 LEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEELAKLQD 386

                         250
                  ....*....|....*
gi 530374448 2724 KYDASLKELAQLKEQ 2738
Cdd:PHA02562  387 ELDKIVKTKSELVKE 401
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 795-1009 6.35e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 6.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  795 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM 874
Cdd:COG3883    16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  875 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNydemspagQISKEELQHEFDLLKKENE 953
Cdd:COG3883    96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKADKAELEAK--------KAELEAKLAELEALKAELE 167

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448  954 QRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKE 1009
Cdd:COG3883   168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2001-2170 6.91e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 41.52  E-value: 6.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2001 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2076
Cdd:NF033928   88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2077 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2133
Cdd:NF033928  165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 530374448 2134 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2170
Cdd:NF033928  245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
46 PHA02562
endonuclease subunit; Provisional
 2395-2640 7.22e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 7.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2395 NKKAVDKTNQLMETLkTIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKE 2474
Cdd:PHA02562  172 NKDKIRELNQQIQTL-DMKIDHIQQ--QIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVM 248

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2475 EIRGLRSHMDDLNSENAKLDAELIQYREDlnqvitIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSF 2554
Cdd:PHA02562  249 DIEDPSAALNKLNTAAAKIKSKIEQFQKV------IKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHSLEKLDTAI 322

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2555 NALQE---EKQDLSKEIESLKVSISQLTRQVTAlqeegtlglYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK 2631
Cdd:PHA02562  323 DELEEimdEFNEQSKKLLELKNKISTNKQSLIT---------LVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVK 393


                  ....*....
gi 530374448 2632 EAAKKVGEI 2640
Cdd:PHA02562  394 TKSELVKEK 402
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 658-1372 7.22e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 42.35  E-value: 7.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   658 LELELNFHKAQEIYEKnLDEKAKEISNLNQLIEEFKKNADNNSSAFTA----LSEERDQLLSQVKElSMVTELRAQVKQL 733
Cdd:TIGR01612 1005 LKANLGKNKENMLYHQ-FDEKEKATNDIEQKIEDANKNIPNIEIAIHTsiynIIDEIEKEIGKNIE-LLNKEILEEAEIN 1082

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   734 EMNLAE-AERQRRLDYESQTAHDNL-LTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEV 811
Cdd:TIGR01612 1083 ITNFNEiKEKLKHYNFDDFGKEENIkYADEINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA 1162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   812 LEGaERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRdVETLQQTIEEkdqqVTEISFSMTEKM-----VQLNEEKF 886
Cdd:TIGR01612 1163 ISN-DDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAE-IEKDKTSLEE----VKGINLSYGKNLgklflEKIDEEKK 1236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   887 SLGVEIKTLKEQLNLLsraEEAKKEQVEEDNEVSSGLKQNyDEMSPAgQISKEELQHEFDLLKKENEQRKRKLQAALinr 966
Cdd:TIGR01612 1237 KSEHMIKAMEAYIEDL---DEIKEKSPEIENEMGIEMDIK-AEMETF-NISHDDDKDHHIISKKHDENISDIREKSL--- 1308

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448   967 kELLQRVSRlEEELANLKDESKKEIplsetergeVEEDKENkeysekcvtskcQEIEIYLKQTISEKEV-ELQHIRKDLE 1045
Cdd:TIGR01612 1309 -KIIEDFSE-ESDINDIKKELQKNL---------LDAQKHN------------SDINLYLNEIANIYNIlKLNKIKKIID 1365

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1046 EKlaaeEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAI--IQKLITSNTDASDGDSV---ALVKETVVISPPcTGSSE 1120
Cdd:TIGR01612 1366 EV----KEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLeeCKSKIESTLDDKDIDECikkIKELKNHILSEE-SNIDT 1440

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1121 HWK--PELEEKILALEKEKEQLQKKLQEALTSRKailKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLR 1198
Cdd:TIGR01612 1441 YFKnaDENNENVLLLFKNIEMADNKSQHILKIKK---DNATNDHDFNINELKEHIDKSKGCKDEADKNAKAIEKNKELFE 1517

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1199 QLQIQVRESIDgKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLES-------NLCPDWPSHSEDASALQGGTSVAQI 1271
Cdd:TIGR01612 1518 QYKKDVTELLN-KYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAekseqkiKEIKKEKFRIEDDAAKNDKSNKAAI 1596

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1272 KAQLKEIEAEKVELELkvssttSELTKKSEEVFQLQEQINKQ--GLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLE 1349
Cdd:TIGR01612 1597 DIQLSLENFENKFLKI------SDIKKKINDCLKETESIEKKisSFSIDSQDTELKENGDNLNSLQEFLESLKDQKKNIE 1670

                          730       740
                   ....*....|....*....|...
gi 530374448  1350 hlrELQPKLDELQKLISKKEEDV 1372
Cdd:TIGR01612 1671 ---DKKKELDELDSEIEKIEIDV 1690
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
775-1178 7.28e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 7.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  775 KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELS--QALSQKELEITKMDQLLLEKKRD 852
Cdd:PRK03918  232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELRE 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  853 VETLQQTIEEKDQQVTEisfsmteKMVQLNEEKfslgVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSP 932
Cdd:PRK03918  312 IEKRLSRLEEEINGIEE-------RIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKR 380

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  933 AGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKdESKKEIPLSETERGEVEEDKENKEYse 1012
Cdd:PRK03918  381 LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELK-KAKGKCPVCGRELTEEHRKELLEEY-- 457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1013 kcvTSKCQEIEIYLKqTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQ--TLQDKTNQIDL--LQAEISENQAIIQK 1088
Cdd:PRK03918  458 ---TAELKRIEKELK-EIEEKERKLRKELRELEKVLKKESELIKLKELAEQlkELEEKLKKYNLeeLEKKAEEYEKLKEK 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1089 LITSntdasDGDSVALVKETvvisppctgssehwkpeleEKILALEKEKEQLQKKLQEALTSRKAILKKAQEK----ERH 1164
Cdd:PRK03918  534 LIKL-----KGEIKSLKKEL-------------------EKLEELKKKLAELEKKLDELEEELAELLKELEELgfesVEE 589

                         410
                  ....*....|....
gi 530374448 1165 LREELKQQKDDYNR 1178
Cdd:PRK03918  590 LEERLKELEPFYNE 603
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
214-398 7.67e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 7.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  214 AAQKLRVLQRKLEEheeslvgraqvvdlLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVA 293
Cdd:COG4913   608 NRAKLAALEAELAE--------------LEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAEL 673

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  294 ERKLS--------FHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQ----ELQSACDA 361
Cdd:COG4913   674 EAELErldassddLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDlarlELRALLEE 753

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 530374448  362 LKDQnskLLQDKNEQAVQSA--QTIQQLEDQLQQKSKEI 398
Cdd:COG4913   754 RFAA---ALGDAVERELRENleERIDALRARLNRAEEEL 789
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1811-2347 7.83e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.08  E-value: 7.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1811 ERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERL 1890
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1891 MNQLAELNGsignycqdvtdAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSH 1970
Cdd:pfam01576   85 EEEEERSQQ-----------LQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  1971 AKELQEL-------LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAS 2043
Cdd:pfam01576  154 RKLLEERiseftsnLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAE 233

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2044 FKVLLDDTQSEAARVLA---DNLKLKKELQSNKESVKSQMKQKDEDLERRlEQAEEKHLKEKKNMQEKLDALRREKVHLE 2120
Cdd:pfam01576  234 LRAQLAKKEEELQAALArleEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQRRDLGEELEALKTELEDTL 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2121 ETIGEIQVTLNKKDKEVQQLQENLDSTV----TQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEE-------E 2189
Cdd:pfam01576  313 DTTAAQQELRSKREQEVTELKKALEEETrsheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenaelqaE 392

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2190 IRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWE---SKAQTEVQ-------LQQKVCDTLQGENKELLSQLEE 2259
Cdd:pfam01576  393 LRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAeklSKLQSELEsvssllnEAEGKNIKLSKDVSSLESQLQD 472

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  2260 TRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE 2339
Cdd:pfam01576  473 TQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQR 552


                   ....*...
gi 530374448  2340 EINMKEQK 2347
Cdd:pfam01576  553 ELEALTQQ 560
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1804-1957 7.86e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 40.68  E-value: 7.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1804 QQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKE------ 1877
Cdd:COG1579    17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1878 ---TAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1954
Cdd:COG1579    97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                  ...
gi 530374448 1955 LEK 1957
Cdd:COG1579   177 LAL 179
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2435-2721 8.34e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 8.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2435 NDRDRIVGDY-------QQLEErhlsiileKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdAELIQYREDLNQV 2507
Cdd:COG4913   593 DDRRRIRSRYvlgfdnrAKLAA--------LEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV 663

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2508 itikDSQQKQL--LEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTAL 2585
Cdd:COG4913   664 ----ASAEREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 2586 QEEGTLGLyHAQLkvkeeEVHRLSALFSSSQKRIAE-LEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETET 2664
Cdd:COG4913   740 EDLARLEL-RALL-----EERFAAALGDAVERELREnLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLES 813

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530374448 2665 AEERVAELAR----DLVEMEQKLLMVTKENkgltaQIQSFGRSMSSLQNSRDHANEELDEL 2721
Cdd:COG4913   814 LPEYLALLDRleedGLPEYEERFKELLNEN-----SIEFVADLLSKLRRAIREIKERIDPL 869
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
775-965 8.93e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 8.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  775 KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN--KESEVLEGAERVRHISSKVEELSQALSQKELEITKmdqlLLEKKRD 852
Cdd:COG4913   611 KLAALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDASSDD 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  853 VETLQQTIEEKDQQVTEisfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEE-DNEVSSGLKQNYDEMS 931
Cdd:COG4913   687 LAALEEQLEELEAELEE-----------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAaEDLARLELRALLEERF 755

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 530374448  932 PAGQISK--EELQHEFDLLKKENEQRKRKLQAALIN 965
Cdd:COG4913   756 AAALGDAveRELRENLEERIDALRARLNRAEEELER 791
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1914-2067 9.94e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.77  E-value: 9.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1914 KNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEkiqgaqkepgnkSHAKELQELLKEKQQEVKQLQ---- 1989
Cdd:COG2433   386 IEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQV--ERLE------------AEVEELEAELEEKDERIERLErels 451

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448 1990 ------KDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKK-AQAELASFKVLLDDTqSEAARVLADN 2062
Cdd:COG2433   452 earseeRREIRKDREISRLDREIERLERELEEERERIEELKRKLERLKELWKLeHSGELVPVKVVEKFT-KEAIRRLEEE 530


                  ....*
gi 530374448 2063 LKLKK 2067
Cdd:COG2433   531 YGLKE 535
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 164-284 9.95e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.58  E-value: 9.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530374448  164 QAQLTQAQAEQPAQSSTeMEEFVMMKQQLQEKEEfISTLQAQLSQTQAEQAAQKLRVL------QRKLE-----EHEESL 232
Cdd:PRK10929  172 QAQLTALQAESAALKAL-VDELELAQLSANNRQE-LARLRSELAKKRSQQLDAYLQALrnqlnsQRQREaeralESTELL 249

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530374448  233 vgrAQVVDLLQQELTAAEQRNQILSQQL------------QQMEAEHNTL--RNTVETEREESKIL 284
Cdd:PRK10929  250 ---AEQSGDLPKSIVAQFKINRELSQALnqqaqrmdliasQQRQAASQTLqvRQALNTLREQSQWL 312
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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