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Conserved domains on  [gi|529012147|ref|XP_005226932|]
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T-cell differentiation antigen CD6 isoform X5 [Bos taurus]

Protein Classification

SR and SRCR domain-containing protein( domain architecture ID 12193687)

SR and SRCR domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 165-264 3.41e-45

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


:

Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 155.58  E-value: 3.41e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529012147   165 LKLVGGGSPCEGRVEMLEHGQWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFAPGQGRIHWDQVNCTGLETYLWHC 244
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80

                           90       100
                   ....*....|....*....|.
gi 529012147   245 PGLP-GNGYCGHKEDAGVVCS 264
Cdd:smart00202  81 PHSGwGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 274-365 3.76e-24

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


:

Pssm-ID: 459844  Cd Length: 98  Bit Score: 97.06  E-value: 3.76e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529012147  274 GTDPCEGQVEVYFRGVWNTVCDSEWYDSEANVLCQDLGCGTVARVPKG---LPHSLSGKMFYS---CKGKESTLSKCFWR 347
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGcsyFGPGSTGPIWLDdvrCSGNETSLWQCPHR 80

                          90
                  ....*....|....*...
gi 529012147  348 FNNSNLCRQSQAARVLCS 365
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 165-264 3.41e-45

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 155.58  E-value: 3.41e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529012147   165 LKLVGGGSPCEGRVEMLEHGQWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFAPGQGRIHWDQVNCTGLETYLWHC 244
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80

                           90       100
                   ....*....|....*....|.
gi 529012147   245 PGLP-GNGYCGHKEDAGVVCS 264
Cdd:smart00202  81 PHSGwGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 170-264 7.18e-35

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 127.11  E-value: 7.18e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529012147  170 GGSPCEGRVEMLEHGQWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLH--FAPGQGRIHWDQVNCTGLETYLWHCP-G 246
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGCSyfGPGSTGPIWLDDVRCSGNETSLWQCPhR 80

                          90
                  ....*....|....*...
gi 529012147  247 LPGNGYCGHKEDAGVVCS 264
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 274-365 3.76e-24

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 97.06  E-value: 3.76e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529012147  274 GTDPCEGQVEVYFRGVWNTVCDSEWYDSEANVLCQDLGCGTVARVPKG---LPHSLSGKMFYS---CKGKESTLSKCFWR 347
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGcsyFGPGSTGPIWLDdvrCSGNETSLWQCPHR 80

                          90
                  ....*....|....*...
gi 529012147  348 FNNSNLCRQSQAARVLCS 365
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 269-365 9.98e-24

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 95.87  E-value: 9.98e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529012147   269 WRLTGGTDPCEGQVEVYFRGVWNTVCDSEWYDSEANVLCQDLGCGTVARVPKG-LPHSLSGKMFY---SCKGKESTLSKC 344
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSaYFGPGSGPIWLdnvRCSGTEASLSDC 80

                           90       100
                   ....*....|....*....|.
gi 529012147   345 FWRFNNSNLCRQSQAARVLCS 365
Cdd:smart00202  81 PHSGWGSHNCSHGEDAGVVCS 101
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 165-264 3.41e-45

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 155.58  E-value: 3.41e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529012147   165 LKLVGGGSPCEGRVEMLEHGQWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFAPGQGRIHWDQVNCTGLETYLWHC 244
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80

                           90       100
                   ....*....|....*....|.
gi 529012147   245 PGLP-GNGYCGHKEDAGVVCS 264
Cdd:smart00202  81 PHSGwGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 170-264 7.18e-35

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 127.11  E-value: 7.18e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529012147  170 GGSPCEGRVEMLEHGQWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLH--FAPGQGRIHWDQVNCTGLETYLWHCP-G 246
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGCSyfGPGSTGPIWLDDVRCSGNETSLWQCPhR 80

                          90
                  ....*....|....*...
gi 529012147  247 LPGNGYCGHKEDAGVVCS 264
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 274-365 3.76e-24

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 97.06  E-value: 3.76e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529012147  274 GTDPCEGQVEVYFRGVWNTVCDSEWYDSEANVLCQDLGCGTVARVPKG---LPHSLSGKMFYS---CKGKESTLSKCFWR 347
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCGGAVSAPSGcsyFGPGSTGPIWLDdvrCSGNETSLWQCPHR 80

                          90
                  ....*....|....*...
gi 529012147  348 FNNSNLCRQSQAARVLCS 365
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 269-365 9.98e-24

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 95.87  E-value: 9.98e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 529012147   269 WRLTGGTDPCEGQVEVYFRGVWNTVCDSEWYDSEANVLCQDLGCGTVARVPKG-LPHSLSGKMFY---SCKGKESTLSKC 344
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSaYFGPGSGPIWLdnvRCSGTEASLSDC 80

                           90       100
                   ....*....|....*....|.
gi 529012147   345 FWRFNNSNLCRQSQAARVLCS 365
Cdd:smart00202  81 PHSGWGSHNCSHGEDAGVVCS 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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