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Conserved domains on  [gi|1387211771|ref|XP_005217374|]
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membrane cofactor protein isoform X8 [Bos taurus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 43-294 3.97e-54

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 180.62  E-value: 3.97e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771  43 CDDPPRFVSMKPQGTLK----PSYSPGEQIVYECRLGFQPVTPGQVLALVCqdNNTWSSLQEgCKKRRCPTLADPTNGQV 118
Cdd:PHA02927   21 CTIPSRPINMKFKNSVEtdanANYNIGDTIEYLCLPGYRKQKMGPIYAKCT--GTGWTLFNQ-CIKRRCPSPRDIDNGQL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 119 ILvnGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYtNNHKDVFEYNEVVTY 198
Cdd:PHA02927   98 DI--GGVDFGSSITYSCNSGYQLIGESKSYCELGSTGSMVWNPEAPICESVKCQSPPSISNGRH-NGYEDFYTDGSVVTY 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 199 SCDPSngpdeYSLVGESKLTCIGnGEWSSqPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVV 278
Cdd:PHA02927  175 SCNSG-----YSLIGNSGVLCSG-GEWSD-PPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSST 247

                         250
                  ....*....|....*.
gi 1387211771 279 CGENSTWEPELPKCIK 294
Cdd:PHA02927  248 CSPGNTWQPELPKCVR 263
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 284-372 2.15e-03

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.44  E-value: 2.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 284 TWEPELPKciKVSIPPSTQSPIPSTQPPVPSVSVSTRSTQHP----VPSVSVSTRSTQHPIPNVSDSKPTSPTMTSGLSH 359
Cdd:PTZ00449  576 SKKPEFPK--DPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPelldIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKI 653

                          90
                  ....*....|...
gi 1387211771 360 PGHPPRPTDASPP 372
Cdd:PTZ00449  654 IKSPKPPKSPKPP 666
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 43-294 3.97e-54

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 180.62  E-value: 3.97e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771  43 CDDPPRFVSMKPQGTLK----PSYSPGEQIVYECRLGFQPVTPGQVLALVCqdNNTWSSLQEgCKKRRCPTLADPTNGQV 118
Cdd:PHA02927   21 CTIPSRPINMKFKNSVEtdanANYNIGDTIEYLCLPGYRKQKMGPIYAKCT--GTGWTLFNQ-CIKRRCPSPRDIDNGQL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 119 ILvnGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYtNNHKDVFEYNEVVTY 198
Cdd:PHA02927   98 DI--GGVDFGSSITYSCNSGYQLIGESKSYCELGSTGSMVWNPEAPICESVKCQSPPSISNGRH-NGYEDFYTDGSVVTY 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 199 SCDPSngpdeYSLVGESKLTCIGnGEWSSqPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVV 278
Cdd:PHA02927  175 SCNSG-----YSLIGNSGVLCSG-GEWSD-PPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSST 247

                         250
                  ....*....|....*.
gi 1387211771 279 CGENSTWEPELPKCIK 294
Cdd:PHA02927  248 CSPGNTWQPELPKCVR 263
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 171-233 2.70e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 64.02  E-value: 2.70e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387211771 171 CQPPPEIQNGKYTNnHKDVFEYNEVVTYSCDPSngpdeYSLVGESKLTCIGNGEWSSQPPQCK 233
Cdd:cd00033     1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEG-----YTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 171-232 1.79e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.08  E-value: 1.79e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387211771  171 CQPPPEIQNGKYTNnHKDVFEYNEVVTYSCDPSngpdeYSLVGESKLTCIGNGEWSSQPPQC 232
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPG-----YTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
171-232 1.07e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 56.74  E-value: 1.07e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387211771 171 CQPPPEIQNGKYTNNhKDVFEYNEVVTYSCDPSngpdeYSLVGESKLTCIGNGEWSSQPPQC 232
Cdd:pfam00084   1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPG-----YRLVGSPTITCQEDGTWSPPFPEC 56
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 284-372 2.15e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.44  E-value: 2.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 284 TWEPELPKciKVSIPPSTQSPIPSTQPPVPSVSVSTRSTQHP----VPSVSVSTRSTQHPIPNVSDSKPTSPTMTSGLSH 359
Cdd:PTZ00449  576 SKKPEFPK--DPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPelldIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKI 653

                          90
                  ....*....|...
gi 1387211771 360 PGHPPRPTDASPP 372
Cdd:PTZ00449  654 IKSPKPPKSPKPP 666
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 299-374 2.31e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 40.28  E-value: 2.31e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387211771 299 PSTQSPIPSTQPPVPSVSVSTRSTQHPVPSVSVSTRSTQHPIPNVSDSKPTSPTMTSGLSHPGHP---PRPTDASPPNG 374
Cdd:pfam05109 518 PNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAvttPTPNATSPTVG 596
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 43-294 3.97e-54

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 180.62  E-value: 3.97e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771  43 CDDPPRFVSMKPQGTLK----PSYSPGEQIVYECRLGFQPVTPGQVLALVCqdNNTWSSLQEgCKKRRCPTLADPTNGQV 118
Cdd:PHA02927   21 CTIPSRPINMKFKNSVEtdanANYNIGDTIEYLCLPGYRKQKMGPIYAKCT--GTGWTLFNQ-CIKRRCPSPRDIDNGQL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 119 ILvnGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVNWSDNPPTCEKILCQPPPEIQNGKYtNNHKDVFEYNEVVTY 198
Cdd:PHA02927   98 DI--GGVDFGSSITYSCNSGYQLIGESKSYCELGSTGSMVWNPEAPICESVKCQSPPSISNGRH-NGYEDFYTDGSVVTY 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 199 SCDPSngpdeYSLVGESKLTCIGnGEWSSqPPQCKVVKCVYPAIEHGTIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVV 278
Cdd:PHA02927  175 SCNSG-----YSLIGNSGVLCSG-GEWSD-PPTCQIVKCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYKLSGSSSST 247

                         250
                  ....*....|....*.
gi 1387211771 279 CGENSTWEPELPKCIK 294
Cdd:PHA02927  248 CSPGNTWQPELPKCVR 263
PHA02639 PHA02639
EEV host range protein; Provisional
 101-294 2.14e-32

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 124.01  E-value: 2.14e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 101 GCKKRRCPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGTGVnWSDNPPTCEKILCQPPPEIQNG 180
Cdd:PHA02639   16 GVKSIYCDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-WSNKAPFCMLKECNDPPSIING 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 181 KYTNNhKDVFEYNEVVTYSCDPSNGPdEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHGTIvSGF--GPKYYYK 258
Cdd:PHA02639   95 KIYNK-REMYKVGDEIYYVCNEHKGV-QYSLVGNEKITCIQDKSWKPDPPICKMINCRFPALQNGYI-NGIpsNKKFYYK 171

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1387211771 259 ATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIK 294
Cdd:PHA02639  172 TRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCVR 207
PHA02831 PHA02831
EEV host range protein; Provisional
 130-303 1.09e-30

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 118.56  E-value: 1.09e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 130 EVHYVCNNGYyllgtNISYCEVSSGTgvnWSDNPPTCEKILCQPPPEIQNGkYTNNHKDVFEYNEVVTYSCDpSNGPDEY 209
Cdd:PHA02831   45 NLEYKCNNNF-----DKVFVTCNNGS---WSTKNMCIGKRNCKDPVTILNG-YIKNKKDQYSFGDSVTYACK-VNKLEKY 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 210 SLVGESKLTCIgNGEWSSQPPQCKVVKCVYPAIEHGtIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPEL 289
Cdd:PHA02831  115 SIVGNETVKCI-NKQWVPKYPVCKLIRCKYPALQNG-FLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGI 192

                         170
                  ....*....|....
gi 1387211771 290 PKCIKVSIPPSTQS 303
Cdd:PHA02831  193 PKCVKDKVHNEIQP 206
PHA02817 PHA02817
EEV Host range protein; Provisional
 166-297 3.38e-26

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 105.02  E-value: 3.38e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 166 CEKILCQPPPEIQNGkYTNNHKDVFEYNEVVTYSCDPSNGPDEYSLVGESKLTCIGNGEWSSQPPQCKVVKCVYPAIEHG 245
Cdd:PHA02817   19 CDLNKCCYPPSIKNG-YIYNKKTEYNIGSNVTFFCGNNTRGVRYTLVGEKNIICEKDGKWNKEFPVCKIIRCRFPALQNG 97

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1387211771 246 tIVSGF--GPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCIKVSI 297
Cdd:PHA02817   98 -FVNGIpdSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSRDNI 150
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 171-233 2.70e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 64.02  E-value: 2.70e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1387211771 171 CQPPPEIQNGKYTNnHKDVFEYNEVVTYSCDPSngpdeYSLVGESKLTCIGNGEWSSQPPQCK 233
Cdd:cd00033     1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEG-----YTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 107-167 8.18e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 59.78  E-value: 8.18e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387211771 107 CPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEVSSGtgvnWSDNPPTCE 167
Cdd:cd00033     1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG----WSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 171-232 1.79e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.08  E-value: 1.79e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387211771  171 CQPPPEIQNGKYTNnHKDVFEYNEVVTYSCDPSngpdeYSLVGESKLTCIGNGEWSSQPPQC 232
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPG-----YTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
171-232 1.07e-10

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 56.74  E-value: 1.07e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1387211771 171 CQPPPEIQNGKYTNNhKDVFEYNEVVTYSCDPSngpdeYSLVGESKLTCIGNGEWSSQPPQC 232
Cdd:pfam00084   1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPG-----YRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 107-166 1.43e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 56.38  E-value: 1.43e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771  107 CPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCEvssgTGVNWSDNPPTC 166
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL----ENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 240-293 1.75e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.24  E-value: 1.75e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1387211771 240 PAIEHGTIVSGFGPkYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKCI 293
Cdd:cd00033     5 PVPENGTVTGSKGS-YSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
237-292 3.57e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.50  E-value: 3.57e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1387211771 237 CVYP-AIEHGtIVSGFGPKYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKC 292
Cdd:pfam00084   1 CPPPpDIPNG-KVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
43-102 6.00e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 51.73  E-value: 6.00e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771  43 CDDPPRFVSMKPQGTlKPSYSPGEQIVYECRLGFQPVTPgqvLALVCQDNNTWSSLQEGC 102
Cdd:pfam00084   1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPGYRLVGS---PTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 240-292 6.37e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 51.76  E-value: 6.37e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1387211771  240 PAIEHGTIVSGFGPkYYYKATVVLKCNEGFNLYGNSVVVCGENSTWEPELPKC 292
Cdd:smart00032   5 PDIENGTVTSSSGT-YSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
107-166 9.63e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 39.79  E-value: 9.63e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 107 CPTLADPTNGQVILVNGSTEFGSEVHYVCNNGYYLLGTNISYCevssGTGVNWSDNPPTC 166
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITC----QEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 43-103 1.54e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 39.37  E-value: 1.54e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1387211771  43 CDDPPRFVSMKPQGTlKPSYSPGEQIVYECRLGFQPVTPGQVlalVCQDNNTWSSLQEGCK 103
Cdd:cd00033     1 CPPPPVPENGTVTGS-KGSYSYGSTVTYSCNEGYTLVGSSTI---TCTENGGWSPPPPTCE 57
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 284-372 2.15e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.44  E-value: 2.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 284 TWEPELPKciKVSIPPSTQSPIPSTQPPVPSVSVSTRSTQHP----VPSVSVSTRSTQHPIPNVSDSKPTSPTMTSGLSH 359
Cdd:PTZ00449  576 SKKPEFPK--DPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPelldIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKI 653

                          90
                  ....*....|...
gi 1387211771 360 PGHPPRPTDASPP 372
Cdd:PTZ00449  654 IKSPKPPKSPKPP 666
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 299-374 2.31e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 40.28  E-value: 2.31e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1387211771 299 PSTQSPIPSTQPPVPSVSVSTRSTQHPVPSVSVSTRSTQHPIPNVSDSKPTSPTMTSGLSHPGHP---PRPTDASPPNG 374
Cdd:pfam05109 518 PNATSPTPAVTTPTPNATSPTLGKTSPTSAVTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAvttPTPNATSPTVG 596
DUF4045 pfam13254
Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. ...
 283-373 7.10e-03

Domain of unknown function (DUF4045); This presumed domain is functionally uncharacterized. This domain family is found in bacteria and eukaryotes, and is typically between 384 and 430 amino acids in length.


Pssm-ID: 433066 [Multi-domain]  Cd Length: 415  Bit Score: 38.23  E-value: 7.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 283 STWEPELPKCIKVSIPP---------STQSPIPSTQPPVPSVSVSTRSTQHPVPSVSVSTRSTQHPIPNVSDSKPTSPTM 353
Cdd:pfam13254 245 STDKEQSPAPTSASEPPpktkelpkdSEEPAAPSKSAEASTEKKEPDTESSPETSSEKSAPSLLSPVSKASIDKPLSSPD 324

                          90       100
                  ....*....|....*....|
gi 1387211771 354 TSGLShpghpPRPTDASPPN 373
Cdd:pfam13254 325 RDPLS-----PKPKPQSPPK 339
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 109-300 8.66e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 37.76  E-value: 8.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 109 TLADPTNGQVILVNGSTEFG--SEVHYVCNNGYYLLGTNiSYCEVSsgtgvNWSDNPPtcekilCQPPPEIQNGKYTNNH 186
Cdd:PHA02954   20 TCTVPTMNNAKLTSTETSFNdkQKVTFTCDSGYYSLDPN-AVCETD-----KWKYENP------CKKMCTVSDYVSELYD 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1387211771 187 KDVFEYNEVVTYSCdpsNGPDEYSLVGESKltciGNGEWSSQPpQCKVVKCVYPAIEHGTiVSGFGPKYYYKATVVLKCN 266
Cdd:PHA02954   88 KPLYEVNSTITLIC---KDETKYFRCEEKN----GNTSWNDTV-TCPNAECQPLQLEHGS-CQPVKEKYSFGEHITINCD 158

                         170       180       190
                  ....*....|....*....|....*....|....
gi 1387211771 267 EGFNLYGNSVVVCGENStWEPeLPKCIKVSIPPS 300
Cdd:PHA02954  159 VGYEVIGASYISCTANS-WNV-IPSCQQKCDIPS 190
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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