|
Name |
Accession |
Description |
Interval |
E-value |
| Fibrinogen_C |
pfam00147 |
Fibrinogen beta and gamma chains, C-terminal globular domain; |
1616-1825 |
1.02e-111 |
|
Fibrinogen beta and gamma chains, C-terminal globular domain;
:
Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 353.75 E-value: 1.02e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1616 FPRDCSQAMLNGDTTSGVYTIYLNNDKTQkQEVFCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDL-KEEFWLGL 1694
Cdd:pfam00147 1 FGRDCSDVYNKGAKTSGLYTIRPDGATKP-FEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLsPGEFWLGN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1695 DTLSKITAQGQYELRVDLRDH-GESAHAVYDKFSVGDARTRYRLKVEGYSGTAGD-------SMAYHNGRSFSTFDKDTD 1766
Cdd:pfam00147 80 DKIHLLTKQGPYVLRIDLEDWnGETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDND 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528959928 1767 SAITNCALSYKGAFWYKNCHRVNLMGRY---GDNSHSQGVNWFHWKGHEHSIQFAEMKLRPS 1825
Cdd:pfam00147 160 SPDGNCALSYGGGWWYNNCHAANLNGVYyygGTYSKQNGIIWATWKGRWYSMKKAEMKIRPL 221
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
847-1161 |
3.94e-17 |
|
Fibronectin type 3 domain [General function prediction only];
:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 87.37 E-value: 3.94e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 847 TSIDLTHEENQYSIGNLKPDTEYEVALISRRADMSSNPAKE----TFTTGLDAPRNLRRISQTDNSITLEWRNVKA-AAD 921
Cdd:COG3401 183 TSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDPVTEsDAT 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 922 SYRIKYAPISGGDHAEV-EVPRSqqtttRTTLTGLRPGTEYGIGVSAVKGDKE----SDPATINAATEL-DTPKDLRISD 995
Cdd:COG3401 263 GYRVYRSNSGDGPFTKVaTVTTT-----SYTDTGLTNGTTYYYRVTAVDAAGNesapSNVVSVTTDLTPpAAPSGLTATA 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 996 PTETSLTLVWQ----TPVAKFDRYRlnYSLPSGQPKEVQLTRDTTSFVLRGLEPGQEYSILLTA--EKGRHKSKPARVQA 1069
Cdd:COG3401 338 VGSSSITLSWTassdADVTGYNVYR--STSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdAAGNESAPSEEVSA 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1070 STDHTPELGNLTVTKAGWDGLR-LNWTAADQAYEHFVIQVQEANGVEAAQNLTVPGNLRAVDVPGLKAATPYRVTIHGVI 1148
Cdd:COG3401 416 TTASAASGESLTASVDAVPLTDvAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGS 495
|
330
....*....|...
gi 528959928 1149 RGYRTPVLSAEAS 1161
Cdd:COG3401 496 LVGGSGASSVTNS 508
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1234-1595 |
3.63e-16 |
|
Fibronectin type 3 domain [General function prediction only];
:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 84.28 E-value: 3.63e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1234 TIRGVTRDFSTAPHSVEALTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDSFVLKIRDTKKQSEPLEITLLAPERTRDI 1313
Cdd:COG3401 27 SKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1314 TGLREATEYEIELYGISSGRRSQPVTAIATTAMGSPKEIIFSDITENAASVSWMAPTTQVESFRVTYVPIAGGAPSAVTV 1393
Cdd:COG3401 107 TNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLT 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1394 DGTKTQTRL-LRLLPGADYLVSVIALKGFEESEPVSG----TLTTALDGPSSLVTANITDSEALAMWQPAIAP-VDNYVI 1467
Cdd:COG3401 187 VTSTTLVDGgGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRV 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1468 SYTGERVPEITRTVSGNTVEYALTNLEPATEYTLRIFA------EKGPQKSSTITTKfTTDLDSPRDFTATEVQSETALL 1541
Cdd:COG3401 267 YRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAvdaagnESAPSNVVSVTTD-LTPPAAPSGLTATAVGSSSITL 345
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 528959928 1542 TWRPPRAS-VTGYLlVY--ESVDGTIKEVVLDPDTTSYSLTDLSPSTYYTARIQALN 1595
Cdd:COG3401 346 SWTASSDAdVTGYN-VYrsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVD 401
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1169-1247 |
3.51e-12 |
|
Fibronectin type III domain;
:
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.97 E-value: 3.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1169 GEVTVSEVGWEALKLNWTAPE---GVYEQFLIQVQEPGKEEAAQNLTVPGGLRSVDLPGLKAATHYSITIRGVTRDFSTA 1245
Cdd:pfam00041 4 SNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGP 83
|
..
gi 528959928 1246 PH 1247
Cdd:pfam00041 84 PS 85
|
|
| FN3 super family |
cl27307 |
Fibronectin type 3 domain [General function prediction only]; |
640-920 |
1.06e-11 |
|
Fibronectin type 3 domain [General function prediction only];
The actual alignment was detected with superfamily member COG3401:
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 70.03 E-value: 1.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 640 NLAWDNEMRVTEYLIVYTPTHEDGLEMQFRVPGDQTSATIRELEPGVEYFIRVFAILENKKSIP---VSARVATYLPT-P 715
Cdd:COG3401 157 GTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPsneVSVTTPTTPPSaP 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 716 EGLKFKSIKETSVEVEWDPLDIAFETWEVIFRNMNKDDE-EEITKSlrrPETTYRQTGLAPGQEYE--ISLHIVKNNTRG 792
Cdd:COG3401 237 TGLTATADTPGSVTLSWDPVTESDATGYRVYRSNSGDGPfTKVATV---TTTSYTDTGLTNGTTYYyrVTAVDAAGNESA 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 793 P-GLKRVTT--TRLDAPSQIEVKDVTDTTALITWSKPLAE-IDSIELmYGIKDVPGDRTSIDLTHEENQYSIGNLKPDTE 868
Cdd:COG3401 314 PsNVVSVTTdlTPPAAPSGLTATAVGSSSITLSWTASSDAdVTGYNV-YRSTSGGGTYTKIAETVTTTSYTDTGLTPGTT 392
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 528959928 869 YEVALISRRAD-MSSNPAKETFTTGLDAPRNLRRISQTDNSITLEWRNVKAAA 920
Cdd:COG3401 393 YYYKVTAVDAAgNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAA 445
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
408-434 |
7.06e-05 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 41.52 E-value: 7.06e-05
10 20
....*....|....*....|....*..
gi 528959928 408 CPRDCSGHGRCVNGQCVCDEGYTGEDC 434
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
501-528 |
3.53e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 39.59 E-value: 3.53e-04
10 20
....*....|....*....|....*...
gi 528959928 501 CPGDCSQRGRCVDGRCVCEDGFAGPDCA 528
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
594-621 |
9.34e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 38.43 E-value: 9.34e-04
10 20
....*....|....*....|....*...
gi 528959928 594 CPNDCSNWGQCVSGRCVCNEGYTGEDCS 621
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
470-496 |
1.21e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 38.05 E-value: 1.21e-03
10 20
....*....|....*....|....*..
gi 528959928 470 CPHDCHQHGRCVNGMCVCDDAYTGEDC 496
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
532-559 |
1.32e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 37.66 E-value: 1.32e-03
10 20
....*....|....*....|....*...
gi 528959928 532 CPGNCHGRGRCVDGQCVCLEGFTGPDCA 559
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
442-465 |
1.40e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
:
Pssm-ID: 400365 Cd Length: 26 Bit Score: 37.71 E-value: 1.40e-03
10 20
....*....|....*....|....*.
gi 528959928 442 DCHGRGRCVD--GRCECQPGFQGDDC 465
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
221-248 |
2.09e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 37.28 E-value: 2.09e-03
10 20
....*....|....*....|....*...
gi 528959928 221 CPSDCNDQGKCVDGACVCFEGYSGLDCS 248
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
349-372 |
2.24e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
:
Pssm-ID: 400365 Cd Length: 26 Bit Score: 36.94 E-value: 2.24e-03
10 20
....*....|....*....|....*.
gi 528959928 349 ACHGHGRCD--EGQCVCDEGFAGPDC 372
Cdd:pfam07974 1 ICSGRGTCVnqCGKCVCDSGYQGATC 26
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
563-590 |
3.04e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 36.89 E-value: 3.04e-03
10 20
....*....|....*....|....*...
gi 528959928 563 CPGDCHGQGRCVDGQCVCHEGFTGPDCA 590
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
190-216 |
7.88e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 35.74 E-value: 7.88e-03
10 20
....*....|....*....|....*..
gi 528959928 190 CPGNCHLHGQCLDGQCVCHEGFTGEDC 216
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin super family |
cl46594 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
377-403 |
7.96e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
The actual alignment was detected with superfamily member pfam18720:
Pssm-ID: 480934 Cd Length: 29 Bit Score: 35.74 E-value: 7.96e-03
10 20
....*....|....*....|....*..
gi 528959928 377 CPSDCHERGRCVDGRCECNDGFTGADC 403
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Fibrinogen_C |
pfam00147 |
Fibrinogen beta and gamma chains, C-terminal globular domain; |
1616-1825 |
1.02e-111 |
|
Fibrinogen beta and gamma chains, C-terminal globular domain;
Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 353.75 E-value: 1.02e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1616 FPRDCSQAMLNGDTTSGVYTIYLNNDKTQkQEVFCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDL-KEEFWLGL 1694
Cdd:pfam00147 1 FGRDCSDVYNKGAKTSGLYTIRPDGATKP-FEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLsPGEFWLGN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1695 DTLSKITAQGQYELRVDLRDH-GESAHAVYDKFSVGDARTRYRLKVEGYSGTAGD-------SMAYHNGRSFSTFDKDTD 1766
Cdd:pfam00147 80 DKIHLLTKQGPYVLRIDLEDWnGETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDND 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528959928 1767 SAITNCALSYKGAFWYKNCHRVNLMGRY---GDNSHSQGVNWFHWKGHEHSIQFAEMKLRPS 1825
Cdd:pfam00147 160 SPDGNCALSYGGGWWYNNCHAANLNGVYyygGTYSKQNGIIWATWKGRWYSMKKAEMKIRPL 221
|
|
| FReD |
cd00087 |
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
1615-1824 |
1.60e-106 |
|
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.
Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 338.83 E-value: 1.60e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1615 RFPRDCSQAMLNGDTTSGVYTIYLNNDKtQKQEVFCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDLKEEFWLGL 1694
Cdd:cd00087 1 PLPRDCSEVLQRGGRTSGVYTIQPPGSN-EPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1695 DTLSKITAQGQYELRVDLRD-HGESAHAVYDKFSVGDARTRYRLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCA 1773
Cdd:cd00087 80 EKIHLLTSQGPYELRIDLEDwEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 528959928 1774 LSYKGAFWYKNCHRVNLMGRYG----DNSHSQGVNWFHWKGHEHSIQFAEMKLRP 1824
Cdd:cd00087 160 ESYSGGWWYNSCHASNLNGRYYsgghRNEYDNGINWATWKGSTYSLKFTEMKIRP 214
|
|
| FBG |
smart00186 |
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ... |
1616-1824 |
7.23e-106 |
|
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.
Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 336.56 E-value: 7.23e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1616 FPRDCSQAMLNGDTTSGVYTIYLNNDkTQKQEVFCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDLKEEFWLGLD 1695
Cdd:smart00186 1 LPRDCSDVLQNGGKTSGLYTIYPDGS-SRPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1696 TLSKITAQGQYELRVDLRD-HGESAHAVYDKFSVGDARTRYRLKVEGYSGTAGD-SMAYHNGRSFSTFDKDTDSAITNCA 1773
Cdd:smart00186 80 NIHLLTSQGKYELRIDLEDwEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 528959928 1774 LSYKGAFWYKNCHRVNLMGRYG-DNSHSQGVNWFHWKGHEHSIQFAEMKLRP 1824
Cdd:smart00186 160 EEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRP 211
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
847-1161 |
3.94e-17 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 87.37 E-value: 3.94e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 847 TSIDLTHEENQYSIGNLKPDTEYEVALISRRADMSSNPAKE----TFTTGLDAPRNLRRISQTDNSITLEWRNVKA-AAD 921
Cdd:COG3401 183 TSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDPVTEsDAT 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 922 SYRIKYAPISGGDHAEV-EVPRSqqtttRTTLTGLRPGTEYGIGVSAVKGDKE----SDPATINAATEL-DTPKDLRISD 995
Cdd:COG3401 263 GYRVYRSNSGDGPFTKVaTVTTT-----SYTDTGLTNGTTYYYRVTAVDAAGNesapSNVVSVTTDLTPpAAPSGLTATA 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 996 PTETSLTLVWQ----TPVAKFDRYRlnYSLPSGQPKEVQLTRDTTSFVLRGLEPGQEYSILLTA--EKGRHKSKPARVQA 1069
Cdd:COG3401 338 VGSSSITLSWTassdADVTGYNVYR--STSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdAAGNESAPSEEVSA 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1070 STDHTPELGNLTVTKAGWDGLR-LNWTAADQAYEHFVIQVQEANGVEAAQNLTVPGNLRAVDVPGLKAATPYRVTIHGVI 1148
Cdd:COG3401 416 TTASAASGESLTASVDAVPLTDvAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGS 495
|
330
....*....|...
gi 528959928 1149 RGYRTPVLSAEAS 1161
Cdd:COG3401 496 LVGGSGASSVTNS 508
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1234-1595 |
3.63e-16 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 84.28 E-value: 3.63e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1234 TIRGVTRDFSTAPHSVEALTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDSFVLKIRDTKKQSEPLEITLLAPERTRDI 1313
Cdd:COG3401 27 SKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1314 TGLREATEYEIELYGISSGRRSQPVTAIATTAMGSPKEIIFSDITENAASVSWMAPTTQVESFRVTYVPIAGGAPSAVTV 1393
Cdd:COG3401 107 TNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLT 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1394 DGTKTQTRL-LRLLPGADYLVSVIALKGFEESEPVSG----TLTTALDGPSSLVTANITDSEALAMWQPAIAP-VDNYVI 1467
Cdd:COG3401 187 VTSTTLVDGgGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRV 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1468 SYTGERVPEITRTVSGNTVEYALTNLEPATEYTLRIFA------EKGPQKSSTITTKfTTDLDSPRDFTATEVQSETALL 1541
Cdd:COG3401 267 YRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAvdaagnESAPSNVVSVTTD-LTPPAAPSGLTATAVGSSSITL 345
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 528959928 1542 TWRPPRAS-VTGYLlVY--ESVDGTIKEVVLDPDTTSYSLTDLSPSTYYTARIQALN 1595
Cdd:COG3401 346 SWTASSDAdVTGYN-VYrsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVD 401
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1524-1596 |
3.60e-15 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 72.45 E-value: 3.60e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528959928 1524 DSPRDFTATEVQSETALLTWRPPR---ASVTGYLLVYESVDGT--IKEVVLDPDTTSYSLTDLSPSTYYTARIQALNG 1596
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1524-1609 |
8.49e-14 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 68.68 E-value: 8.49e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1524 DSPRDFTATEVQSETALLTWRPPR---ASVTGYLLVYESVD-GTIKEV-VLDPDTTSYSLTDLSPSTYYTARIQALNGTL 1598
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGsGDWKEVeVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 528959928 1599 RSKTVKTI-FTT 1609
Cdd:cd00063 82 ESPPSESVtVTT 93
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1524-1596 |
1.79e-13 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 67.25 E-value: 1.79e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528959928 1524 DSPRDFTATEVQSETALLTWRPPRAS-----VTGYLLVYESVDGTIKEVVLDPDTTSYSLTDLSPSTYYTARIQALNG 1596
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1169-1247 |
3.51e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.97 E-value: 3.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1169 GEVTVSEVGWEALKLNWTAPE---GVYEQFLIQVQEPGKEEAAQNLTVPGGLRSVDLPGLKAATHYSITIRGVTRDFSTA 1245
Cdd:pfam00041 4 SNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGP 83
|
..
gi 528959928 1246 PH 1247
Cdd:pfam00041 84 PS 85
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
986-1065 |
3.69e-12 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 64.05 E-value: 3.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 986 DTPKDLRISDPTETSLTLVWQTPV---AKFDRYRLNYS-LPSGQPKEVQLTR-DTTSFVLRGLEPGQEYSILLTAEKGRH 1060
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYReKGSGDWKEVEVTPgSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
....*
gi 528959928 1061 KSKPA 1065
Cdd:cd00063 82 ESPPS 86
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
986-1064 |
5.13e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.20 E-value: 5.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 986 DTPKDLRISDPTETSLTLVWQTPV---AKFDRYRLNYSLPSGQ--PKEVQLTRDTTSFVLRGLEPGQEYSILLTAEKGRH 1060
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 528959928 1061 KSKP 1064
Cdd:pfam00041 81 EGPP 84
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
640-920 |
1.06e-11 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 70.03 E-value: 1.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 640 NLAWDNEMRVTEYLIVYTPTHEDGLEMQFRVPGDQTSATIRELEPGVEYFIRVFAILENKKSIP---VSARVATYLPT-P 715
Cdd:COG3401 157 GTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPsneVSVTTPTTPPSaP 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 716 EGLKFKSIKETSVEVEWDPLDIAFETWEVIFRNMNKDDE-EEITKSlrrPETTYRQTGLAPGQEYE--ISLHIVKNNTRG 792
Cdd:COG3401 237 TGLTATADTPGSVTLSWDPVTESDATGYRVYRSNSGDGPfTKVATV---TTTSYTDTGLTNGTTYYyrVTAVDAAGNESA 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 793 P-GLKRVTT--TRLDAPSQIEVKDVTDTTALITWSKPLAE-IDSIELmYGIKDVPGDRTSIDLTHEENQYSIGNLKPDTE 868
Cdd:COG3401 314 PsNVVSVTTdlTPPAAPSGLTATAVGSSSITLSWTASSDAdVTGYNV-YRSTSGGGTYTKIAETVTTTSYTDTGLTPGTT 392
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 528959928 869 YEVALISRRAD-MSSNPAKETFTTGLDAPRNLRRISQTDNSITLEWRNVKAAA 920
Cdd:COG3401 393 YYYKVTAVDAAgNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAA 445
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
986-1062 |
2.13e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 61.48 E-value: 2.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 986 DTPKDLRISDPTETSLTLVWQTP-----VAKFDRYRLNYSLPSGQPKEVQLTRDTTSFVLRGLEPGQEYSILLTAEKGRH 1060
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpddgiTGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 528959928 1061 KS 1062
Cdd:smart00060 82 EG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
713-793 |
1.16e-10 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 59.35 E-value: 1.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 713 PTPEGLKFKSIKETSVEVEWDP---LDIAFETWEVIFRNMNkDDEEEITKSLRRPETTYRQTGLAPGQEYEISLHIVKNN 789
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKN-SGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79
|
....
gi 528959928 790 TRGP 793
Cdd:pfam00041 80 GEGP 83
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
804-882 |
6.03e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 54.54 E-value: 6.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 804 DAPSQIEVKDVTDTTALITWSKPLAE-IDSIELMYGIKDVPGDR--TSIDLTHEENQYSIGNLKPDTEYEVALISRRADM 880
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDgITGYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 528959928 881 SS 882
Cdd:smart00060 82 EG 83
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
624-710 |
7.11e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 54.81 E-value: 7.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 624 SPPKDLVVTEVTEETVNLAW----DNEMRVTEYLIVYTPTHEDGLEMQFRVPGDQTSATIRELEPGVEYFIRVFAILENK 699
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWtppeDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|.
gi 528959928 700 KSIPVSARVAT 710
Cdd:cd00063 82 ESPPSESVTVT 92
|
|
| GGGWT_bact |
NF040941 |
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ... |
1626-1659 |
3.88e-06 |
|
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.
Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 45.25 E-value: 3.88e-06
10 20 30
....*....|....*....|....*....|....*
gi 528959928 1626 NGDTTSGVYTIYLNNDKTQK-QEVFCDMTSDGGGW 1659
Cdd:NF040941 9 GPSAPSGVYWIDPDGMGGLApFQVYCDMTTDGGGW 43
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1171-1253 |
5.36e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 46.34 E-value: 5.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1171 VTVSEVGWEALKLNWTAPE---GVYEQFLIQVQEPGKEEAAQNLTVPGGLRSVDLPGLKAATHYSITIRGVTRD-FSTAP 1246
Cdd:cd00063 7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGgESPPS 86
|
....*..
gi 528959928 1247 HSVEALT 1253
Cdd:cd00063 87 ESVTVTT 93
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
1438-1808 |
6.75e-06 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 50.54 E-value: 6.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1438 PSSLVTANITDSEALAMWQPAI--APVDNYVISYTGERVpeitRTVSGNTvEYALTNLEPATEYTLRIFA-EKGPQKSST 1514
Cdd:COG3979 6 PTGLTASNVTSSSVSLSWDASTdnVGVTGYDVYRGGDQV----ATVTGLT-AWTVTGLTPGTEYTFTVGAcDAAGNVSAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1515 ITTKFTTDLDSPRDFTATEVQSETALltwrppraSVTGYLLVYESVDGTIKEVVLDPDTTSYSLTDLSPSTYYTARIQAL 1594
Cdd:COG3979 81 SGTSTAMFGGSSTTLGSAEGVADTSG--------NLAASGAFFGVTTPPTPSSTLVVDGTTTVNAAATANGGTGGSGGTT 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1595 NGTLRSKTVKTIFTTSGVLYRFPRDCSQAMLNGDTTSGVYTIYLNNDKTQKQEVFCDMTSDGGGWIVFLRRKNGREDFYR 1674
Cdd:COG3979 153 TIITTGVEGGGGSKTAQSLNAITAAGTAALNGGVVGGADEVLTCSAVKDDGSGGAGAGNTYWALNTLGVSDTPSGTTATG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1675 NWKAYAAGFGDLKEEFWLGLDTLSKITAQGQYELRVDLRDHGESAHAVYDKFSVGDARTRYRLKVEGYSGTAGDSMAYHN 1754
Cdd:COG3979 233 GTVGITSAYGAGVSGNAAVNVNAGFVVGNVGGAAGNTGTTSGTATSDAATNDVGDAAVTGLNDGAANGPTGGYGATGTTV 312
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 528959928 1755 GRSFSTFDKDTDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNSHSQGVNWFHW 1808
Cdd:COG3979 313 AGAAGVGGTKSGTGALGLSGAGGAGAAVSGTATGDDDAGADDSTAGVSGAGSTT 366
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
408-434 |
7.06e-05 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 41.52 E-value: 7.06e-05
10 20
....*....|....*....|....*..
gi 528959928 408 CPRDCSGHGRCVNGQCVCDEGYTGEDC 434
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1171-1240 |
1.31e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 42.22 E-value: 1.31e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 528959928 1171 VTVSEVGWEALKLNWTAPE-GVYEQFLIQVQEPGKEEAA--QNLTVPGGLRSVDLPGLKAATHYSITIRGVTR 1240
Cdd:smart00060 7 LRVTDVTSTSVTLSWEPPPdDGITGYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
501-528 |
3.53e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 39.59 E-value: 3.53e-04
10 20
....*....|....*....|....*...
gi 528959928 501 CPGDCSQRGRCVDGRCVCEDGFAGPDCA 528
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
594-621 |
9.34e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 38.43 E-value: 9.34e-04
10 20
....*....|....*....|....*...
gi 528959928 594 CPNDCSNWGQCVSGRCVCNEGYTGEDCS 621
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
470-496 |
1.21e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 38.05 E-value: 1.21e-03
10 20
....*....|....*....|....*..
gi 528959928 470 CPHDCHQHGRCVNGMCVCDDAYTGEDC 496
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
532-559 |
1.32e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.66 E-value: 1.32e-03
10 20
....*....|....*....|....*...
gi 528959928 532 CPGNCHGRGRCVDGQCVCLEGFTGPDCA 559
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
442-465 |
1.40e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 37.71 E-value: 1.40e-03
10 20
....*....|....*....|....*.
gi 528959928 442 DCHGRGRCVD--GRCECQPGFQGDDC 465
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
221-248 |
2.09e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.28 E-value: 2.09e-03
10 20
....*....|....*....|....*...
gi 528959928 221 CPSDCNDQGKCVDGACVCFEGYSGLDCS 248
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
349-372 |
2.24e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 36.94 E-value: 2.24e-03
10 20
....*....|....*....|....*.
gi 528959928 349 ACHGHGRCD--EGQCVCDEGFAGPDC 372
Cdd:pfam07974 1 ICSGRGTCVnqCGKCVCDSGYQGATC 26
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
563-590 |
3.04e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.89 E-value: 3.04e-03
10 20
....*....|....*....|....*...
gi 528959928 563 CPGDCHGQGRCVDGQCVCHEGFTGPDCA 590
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
190-216 |
7.88e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 35.74 E-value: 7.88e-03
10 20
....*....|....*....|....*..
gi 528959928 190 CPGNCHLHGQCLDGQCVCHEGFTGEDC 216
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
377-403 |
7.96e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 35.74 E-value: 7.96e-03
10 20
....*....|....*....|....*..
gi 528959928 377 CPSDCHERGRCVDGRCECNDGFTGADC 403
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Fibrinogen_C |
pfam00147 |
Fibrinogen beta and gamma chains, C-terminal globular domain; |
1616-1825 |
1.02e-111 |
|
Fibrinogen beta and gamma chains, C-terminal globular domain;
Pssm-ID: 395095 [Multi-domain] Cd Length: 221 Bit Score: 353.75 E-value: 1.02e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1616 FPRDCSQAMLNGDTTSGVYTIYLNNDKTQkQEVFCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDL-KEEFWLGL 1694
Cdd:pfam00147 1 FGRDCSDVYNKGAKTSGLYTIRPDGATKP-FEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLsPGEFWLGN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1695 DTLSKITAQGQYELRVDLRDH-GESAHAVYDKFSVGDARTRYRLKVEGYSGTAGD-------SMAYHNGRSFSTFDKDTD 1766
Cdd:pfam00147 80 DKIHLLTKQGPYVLRIDLEDWnGETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDND 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528959928 1767 SAITNCALSYKGAFWYKNCHRVNLMGRY---GDNSHSQGVNWFHWKGHEHSIQFAEMKLRPS 1825
Cdd:pfam00147 160 SPDGNCALSYGGGWWYNNCHAANLNGVYyygGTYSKQNGIIWATWKGRWYSMKKAEMKIRPL 221
|
|
| FReD |
cd00087 |
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ... |
1615-1824 |
1.60e-106 |
|
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.
Pssm-ID: 238040 [Multi-domain] Cd Length: 215 Bit Score: 338.83 E-value: 1.60e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1615 RFPRDCSQAMLNGDTTSGVYTIYLNNDKtQKQEVFCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDLKEEFWLGL 1694
Cdd:cd00087 1 PLPRDCSEVLQRGGRTSGVYTIQPPGSN-EPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1695 DTLSKITAQGQYELRVDLRD-HGESAHAVYDKFSVGDARTRYRLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCA 1773
Cdd:cd00087 80 EKIHLLTSQGPYELRIDLEDwEGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 528959928 1774 LSYKGAFWYKNCHRVNLMGRYG----DNSHSQGVNWFHWKGHEHSIQFAEMKLRP 1824
Cdd:cd00087 160 ESYSGGWWYNSCHASNLNGRYYsgghRNEYDNGINWATWKGSTYSLKFTEMKIRP 214
|
|
| FBG |
smart00186 |
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ... |
1616-1824 |
7.23e-106 |
|
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.
Pssm-ID: 214548 [Multi-domain] Cd Length: 212 Bit Score: 336.56 E-value: 7.23e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1616 FPRDCSQAMLNGDTTSGVYTIYLNNDkTQKQEVFCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDLKEEFWLGLD 1695
Cdd:smart00186 1 LPRDCSDVLQNGGKTSGLYTIYPDGS-SRPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1696 TLSKITAQGQYELRVDLRD-HGESAHAVYDKFSVGDARTRYRLKVEGYSGTAGD-SMAYHNGRSFSTFDKDTDSAITNCA 1773
Cdd:smart00186 80 NIHLLTSQGKYELRIDLEDwEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 528959928 1774 LSYKGAFWYKNCHRVNLMGRYG-DNSHSQGVNWFHWKGHEHSIQFAEMKLRP 1824
Cdd:smart00186 160 EEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRP 211
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
847-1161 |
3.94e-17 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 87.37 E-value: 3.94e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 847 TSIDLTHEENQYSIGNLKPDTEYEVALISRRADMSSNPAKE----TFTTGLDAPRNLRRISQTDNSITLEWRNVKA-AAD 921
Cdd:COG3401 183 TSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDPVTEsDAT 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 922 SYRIKYAPISGGDHAEV-EVPRSqqtttRTTLTGLRPGTEYGIGVSAVKGDKE----SDPATINAATEL-DTPKDLRISD 995
Cdd:COG3401 263 GYRVYRSNSGDGPFTKVaTVTTT-----SYTDTGLTNGTTYYYRVTAVDAAGNesapSNVVSVTTDLTPpAAPSGLTATA 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 996 PTETSLTLVWQ----TPVAKFDRYRlnYSLPSGQPKEVQLTRDTTSFVLRGLEPGQEYSILLTA--EKGRHKSKPARVQA 1069
Cdd:COG3401 338 VGSSSITLSWTassdADVTGYNVYR--STSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAvdAAGNESAPSEEVSA 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1070 STDHTPELGNLTVTKAGWDGLR-LNWTAADQAYEHFVIQVQEANGVEAAQNLTVPGNLRAVDVPGLKAATPYRVTIHGVI 1148
Cdd:COG3401 416 TTASAASGESLTASVDAVPLTDvAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGS 495
|
330
....*....|...
gi 528959928 1149 RGYRTPVLSAEAS 1161
Cdd:COG3401 496 LVGGSGASSVTNS 508
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1234-1595 |
3.63e-16 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 84.28 E-value: 3.63e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1234 TIRGVTRDFSTAPHSVEALTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDSFVLKIRDTKKQSEPLEITLLAPERTRDI 1313
Cdd:COG3401 27 SKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1314 TGLREATEYEIELYGISSGRRSQPVTAIATTAMGSPKEIIFSDITENAASVSWMAPTTQVESFRVTYVPIAGGAPSAVTV 1393
Cdd:COG3401 107 TNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLT 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1394 DGTKTQTRL-LRLLPGADYLVSVIALKGFEESEPVSG----TLTTALDGPSSLVTANITDSEALAMWQPAIAP-VDNYVI 1467
Cdd:COG3401 187 VTSTTLVDGgGDIEPGTTYYYRVAATDTGGESAPSNEvsvtTPTTPPSAPTGLTATADTPGSVTLSWDPVTESdATGYRV 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1468 SYTGERVPEITRTVSGNTVEYALTNLEPATEYTLRIFA------EKGPQKSSTITTKfTTDLDSPRDFTATEVQSETALL 1541
Cdd:COG3401 267 YRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAvdaagnESAPSNVVSVTTD-LTPPAAPSGLTATAVGSSSITL 345
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 528959928 1542 TWRPPRAS-VTGYLlVY--ESVDGTIKEVVLDPDTTSYSLTDLSPSTYYTARIQALN 1595
Cdd:COG3401 346 SWTASSDAdVTGYN-VYrsTSGGGTYTKIAETVTTTSYTDTGLTPGTTYYYKVTAVD 401
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1524-1596 |
3.60e-15 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 72.45 E-value: 3.60e-15
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528959928 1524 DSPRDFTATEVQSETALLTWRPPR---ASVTGYLLVYESVDGT--IKEVVLDPDTTSYSLTDLSPSTYYTARIQALNG 1596
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1524-1609 |
8.49e-14 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 68.68 E-value: 8.49e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1524 DSPRDFTATEVQSETALLTWRPPR---ASVTGYLLVYESVD-GTIKEV-VLDPDTTSYSLTDLSPSTYYTARIQALNGTL 1598
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGsGDWKEVeVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 528959928 1599 RSKTVKTI-FTT 1609
Cdd:cd00063 82 ESPPSESVtVTT 93
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1524-1596 |
1.79e-13 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 67.25 E-value: 1.79e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528959928 1524 DSPRDFTATEVQSETALLTWRPPRAS-----VTGYLLVYESVDGTIKEVVLDPDTTSYSLTDLSPSTYYTARIQALNG 1596
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1169-1247 |
3.51e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.97 E-value: 3.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1169 GEVTVSEVGWEALKLNWTAPE---GVYEQFLIQVQEPGKEEAAQNLTVPGGLRSVDLPGLKAATHYSITIRGVTRDFSTA 1245
Cdd:pfam00041 4 SNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGP 83
|
..
gi 528959928 1246 PH 1247
Cdd:pfam00041 84 PS 85
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
986-1065 |
3.69e-12 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 64.05 E-value: 3.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 986 DTPKDLRISDPTETSLTLVWQTPV---AKFDRYRLNYS-LPSGQPKEVQLTR-DTTSFVLRGLEPGQEYSILLTAEKGRH 1060
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYReKGSGDWKEVEVTPgSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
....*
gi 528959928 1061 KSKPA 1065
Cdd:cd00063 82 ESPPS 86
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
986-1064 |
5.13e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 63.20 E-value: 5.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 986 DTPKDLRISDPTETSLTLVWQTPV---AKFDRYRLNYSLPSGQ--PKEVQLTRDTTSFVLRGLEPGQEYSILLTAEKGRH 1060
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGepWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 528959928 1061 KSKP 1064
Cdd:pfam00041 81 EGPP 84
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1075-1154 |
9.39e-12 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 62.43 E-value: 9.39e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1075 PELGNLTVTKAGWDGLRLNWTAADQ---AYEHFVIQVQEANGVEAAQNLTVPGNLRAVDVPGLKAATPYRVTIHGVIRGY 1151
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPDgngPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
...
gi 528959928 1152 RTP 1154
Cdd:pfam00041 81 EGP 83
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
640-920 |
1.06e-11 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 70.03 E-value: 1.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 640 NLAWDNEMRVTEYLIVYTPTHEDGLEMQFRVPGDQTSATIRELEPGVEYFIRVFAILENKKSIP---VSARVATYLPT-P 715
Cdd:COG3401 157 GTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPsneVSVTTPTTPPSaP 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 716 EGLKFKSIKETSVEVEWDPLDIAFETWEVIFRNMNKDDE-EEITKSlrrPETTYRQTGLAPGQEYE--ISLHIVKNNTRG 792
Cdd:COG3401 237 TGLTATADTPGSVTLSWDPVTESDATGYRVYRSNSGDGPfTKVATV---TTTSYTDTGLTNGTTYYyrVTAVDAAGNESA 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 793 P-GLKRVTT--TRLDAPSQIEVKDVTDTTALITWSKPLAE-IDSIELmYGIKDVPGDRTSIDLTHEENQYSIGNLKPDTE 868
Cdd:COG3401 314 PsNVVSVTTdlTPPAAPSGLTATAVGSSSITLSWTASSDAdVTGYNV-YRSTSGGGTYTKIAETVTTTSYTDTGLTPGTT 392
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 528959928 869 YEVALISRRAD-MSSNPAKETFTTGLDAPRNLRRISQTDNSITLEWRNVKAAA 920
Cdd:COG3401 393 YYYKVTAVDAAgNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAA 445
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
986-1062 |
2.13e-11 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 61.48 E-value: 2.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 986 DTPKDLRISDPTETSLTLVWQTP-----VAKFDRYRLNYSLPSGQPKEVQLTRDTTSFVLRGLEPGQEYSILLTAEKGRH 1060
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPpddgiTGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 528959928 1061 KS 1062
Cdd:smart00060 82 EG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1257-1337 |
2.35e-11 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 61.28 E-value: 2.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1257 PEVDNLLVSDATPDGFRLSWTADE---GVFDSFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISSGR 1333
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 528959928 1334 RSQP 1337
Cdd:pfam00041 81 EGPP 84
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
713-793 |
1.16e-10 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 59.35 E-value: 1.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 713 PTPEGLKFKSIKETSVEVEWDP---LDIAFETWEVIFRNMNkDDEEEITKSLRRPETTYRQTGLAPGQEYEISLHIVKNN 789
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPppdGNGPITGYEVEYRPKN-SGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79
|
....
gi 528959928 790 TRGP 793
Cdd:pfam00041 80 GEGP 83
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
804-891 |
1.32e-10 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 59.43 E-value: 1.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 804 DAPSQIEVKDVTDTTALITWSKPL---AEIDSIELMYGIKDVPGDRTSIDLTHEENQYSIGNLKPDTEYEVALISRRADM 880
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 528959928 881 SSNPAK-ETFTT 891
Cdd:cd00063 82 ESPPSEsVTVTT 93
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1347-1426 |
2.72e-10 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 58.58 E-value: 2.72e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1347 GSPKEIIFSDITENAASVSWMAPTTQ---VESFRVTYVPIAGGAPSA-VTVDGTKTQTRLLRLLPGADYLVSVIALKGFE 1422
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPDGngpITGYEVEYRPKNSGEPWNeITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 528959928 1423 ESEP 1426
Cdd:pfam00041 81 EGPP 84
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
624-779 |
4.12e-10 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 64.64 E-value: 4.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 624 SPPKDLVVTEVTEETVNLAWD--NEMRVTEYlIVYTPTHEDGlemQFRVPGD--QTSATIRELEPGVEYFIRVFAI---- 695
Cdd:COG3401 234 SAPTGLTATADTPGSVTLSWDpvTESDATGY-RVYRSNSGDG---PFTKVATvtTTSYTDTGLTNGTTYYYRVTAVdaag 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 696 LENKKSIPVSARVATYLPT-PEGLKFKSIKETSVEVEWDPLDIAFETWEVIFRNMNKDDE-EEITKSLRrpETTYRQTGL 773
Cdd:COG3401 310 NESAPSNVVSVTTDLTPPAaPSGLTATAVGSSSITLSWTASSDADVTGYNVYRSTSGGGTyTKIAETVT--TTSYTDTGL 387
|
....*.
gi 528959928 774 APGQEY 779
Cdd:COG3401 388 TPGTTY 393
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
804-884 |
9.68e-10 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 57.04 E-value: 9.68e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 804 DAPSQIEVKDVTDTTALITWSKPL---AEIDSIELMYGIKDVPGDRTSIDLTHEENQYSIGNLKPDTEYEVALISRRADM 880
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80
|
....
gi 528959928 881 SSNP 884
Cdd:pfam00041 81 EGPP 84
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1347-1433 |
1.44e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 56.74 E-value: 1.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1347 GSPKEIIFSDITENAASVSWMAPT---TQVESFRVTYVPIAGGAPSAVTV-DGTKTQTRLLRLLPGADYLVSVIALKGFE 1422
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVtPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 528959928 1423 ESEPV-SGTLTT 1433
Cdd:cd00063 82 ESPPSeSVTVTT 93
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1334-1597 |
1.51e-09 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 62.71 E-value: 1.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1334 RSQPVTAIATTAMGSPKEIIFSDITENAASVSW-MAPTTQVESFRVTYVPIAGGAPSAVTVDGTKTQTRLLRLLPGADYL 1412
Cdd:COG3401 37 LVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTgGRAGTTSGVAAVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1413 VSVIALKGFEESEPVSGTLTTALDGPSSLVTANITD--SEALAMWQPAIAPVDNYVISYTGERVPEITRTVSGNTVEYAL 1490
Cdd:COG3401 117 VPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGanASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGG 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1491 TNLEPATEYTLRIFA---EKGPQKSSTIT-TKFTTDLDSPRDFTATEVQSETALLTWRP-PRASVTGYLLVYESVDGTIK 1565
Cdd:COG3401 197 GDIEPGTTYYYRVAAtdtGGESAPSNEVSvTTPTTPPSAPTGLTATADTPGSVTLSWDPvTESDATGYRVYRSNSGDGPF 276
|
250 260 270
....*....|....*....|....*....|..
gi 528959928 1566 EVVLDPDTTSYSLTDLSPSTYYTARIQALNGT 1597
Cdd:COG3401 277 TKVATVTTTSYTDTGLTNGTTYYYRVTAVDAA 308
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
1438-1508 |
1.55e-09 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 56.27 E-value: 1.55e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528959928 1438 PSSLVTANITDSEALAMWQPA---IAPVDNYVISY--TGERVPEITRTVSGNTVEYALTNLEPATEYTLRIFAEKG 1508
Cdd:pfam00041 3 PSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYrpKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
804-882 |
6.03e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 54.54 E-value: 6.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 804 DAPSQIEVKDVTDTTALITWSKPLAE-IDSIELMYGIKDVPGDR--TSIDLTHEENQYSIGNLKPDTEYEVALISRRADM 880
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDgITGYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 528959928 881 SS 882
Cdd:smart00060 82 EG 83
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
624-710 |
7.11e-09 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 54.81 E-value: 7.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 624 SPPKDLVVTEVTEETVNLAW----DNEMRVTEYLIVYTPTHEDGLEMQFRVPGDQTSATIRELEPGVEYFIRVFAILENK 699
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWtppeDDGGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|.
gi 528959928 700 KSIPVSARVAT 710
Cdd:cd00063 82 ESPPSESVTVT 92
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
624-695 |
2.70e-08 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 52.80 E-value: 2.70e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528959928 624 SPPKDLVVTEVTEETVNLAW----DNEMRVTEYLIVYTPTHEDGLEMQFRVPGDQTSATIRELEPGVEYFIRVFAI 695
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWtpppDGNGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAV 76
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1259-1344 |
2.87e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 52.88 E-value: 2.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1259 VDNLLVSDATPDGFRLSWTA---DEGVFDSFVLKIRDtKKQSEPLEITLLAPERTR-DITGLREATEYEIELYGISSGRR 1334
Cdd:cd00063 4 PTNLRVTDVTSTSVTLSWTPpedDGGPITGYVVEYRE-KGSGDWKEVEVTPGSETSyTLTGLKPGTEYEFRVRAVNGGGE 82
|
90
....*....|
gi 528959928 1335 SQPVTAIATT 1344
Cdd:cd00063 83 SPPSESVTVT 92
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1436-1512 |
4.46e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 52.23 E-value: 4.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1436 DGPSSLVTANITDSEALAMWQP-----AIAPVDNYVISYTGERVPEITRTVSGNTVEYALTNLEPATEYTLRIFAEKGPQ 1510
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPppddgITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 528959928 1511 KS 1512
Cdd:smart00060 82 EG 83
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1436-1521 |
5.30e-08 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 52.11 E-value: 5.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1436 DGPSSLVTANITDSEALAMWQPA---IAPVDNYVISY--TGERVPEITRTVSGNTVEYALTNLEPATEYTLRIFAEKGPQ 1510
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPeddGGPITGYVVEYreKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81
|
90
....*....|..
gi 528959928 1511 KS-STITTKFTT 1521
Cdd:cd00063 82 ESpPSESVTVTT 93
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
715-801 |
2.10e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 50.57 E-value: 2.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 715 PEGLKFKSIKETSVEVEWDPLD---IAFETWEVIFRNMNKDDEEEITKSlRRPETTYRQTGLAPGQEYEISLHIVKNNTR 791
Cdd:cd00063 4 PTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVT-PGSETSYTLTGLKPGTEYEFRVRAVNGGGE 82
|
90
....*....|
gi 528959928 792 GPGLKRVTTT 801
Cdd:cd00063 83 SPPSESVTVT 92
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1347-1424 |
6.37e-07 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 48.76 E-value: 6.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1347 GSPKEIIFSDITENAASVSWMAPT-TQVESFRVTYVPIAGGAPSA---VTVDGTKTQTRLLRLLPGADYLVSVIALKGFE 1422
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPdDGITGYIVGYRVEYREEGSEwkeVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 528959928 1423 ES 1424
Cdd:smart00060 82 EG 83
|
|
| FN3 |
COG3401 |
Fibronectin type 3 domain [General function prediction only]; |
1119-1500 |
3.12e-06 |
|
Fibronectin type 3 domain [General function prediction only];
Pssm-ID: 442628 [Multi-domain] Cd Length: 603 Bit Score: 51.93 E-value: 3.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1119 NLTVPGNLRAVDVPGLKAATPYRVTIHGV-IRGYRTPVLSAEASTGDTPHL--GEVTVSEVGWEALKLNWTAPEGVYEQ- 1194
Cdd:COG3401 184 SLTVTSTTLVDGGGDIEPGTTYYYRVAATdTGGESAPSNEVSVTTPTTPPSapTGLTATADTPGSVTLSWDPVTESDATg 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1195 FLIQVQEPGKEEAAQnLTVPGGLRSVDlPGLKAATHYSITIRGVTRDFSTAPHS--VEALTEAEP--EVDNLLVSDATPD 1270
Cdd:COG3401 264 YRVYRSNSGDGPFTK-VATVTTTSYTD-TGLTNGTTYYYRVTAVDAAGNESAPSnvVSVTTDLTPpaAPSGLTATAVGSS 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1271 GFRLSWTA-DEGVFDSFVLKiRDTKKQSEPLEITLLAPERTRDITGLREATEYEielYGI----SSGRRSQP-----VTA 1340
Cdd:COG3401 342 SITLSWTAsSDADVTGYNVY-RSTSGGGTYTKIAETVTTTSYTDTGLTPGTTYY---YKVtavdAAGNESAPseevsATT 417
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1341 IATTAMGSPKEIIFSDITENAASVSWMA-----PTTQVESFRVTYVPIAGGAPSAVTVDGTKTQTRLLRLLP-------G 1408
Cdd:COG3401 418 ASAASGESLTASVDAVPLTDVAGATAAAsaasnPGVSAAVLADGGDTGNAVPFTTTSSTVTATTTDTTTANLsvttgslV 497
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1409 ADYLVSVIALKGFEESEPVSGTLTTALDGPSSLVTANITDSEALAMWqpAIAPVDNYVISYTGERVPeiTRTVSGNTVEY 1488
Cdd:COG3401 498 GGSGASSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVGASTGD--VLITDLVSLTTSASSSVS--GAGLGSGNLYL 573
|
410
....*....|..
gi 528959928 1489 ALTNLEPATEYT 1500
Cdd:COG3401 574 ITTLGGSLLTTT 585
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
713-794 |
3.63e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 46.84 E-value: 3.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 713 PTPEGLKFKSIKETSVEVEWDPLDIAFETWEVI--FRNMNKDDEEEITKSLRRPETTYRQTGLAPGQEYEISLHIVknNT 790
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVgyRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV--NG 79
|
....
gi 528959928 791 RGPG 794
Cdd:smart00060 80 AGEG 83
|
|
| fn3 |
pfam00041 |
Fibronectin type III domain; |
894-976 |
3.72e-06 |
|
Fibronectin type III domain;
Pssm-ID: 394996 [Multi-domain] Cd Length: 85 Bit Score: 46.64 E-value: 3.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 894 DAPRNLRRISQTDNSITLEW---RNVKAAADSYRIKYAPISGGDHA-EVEVPRSQqttTRTTLTGLRPGTEYGIGVSAVK 969
Cdd:pfam00041 1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYRPKNSGEPWnEITVPGTT---TSVTLTGLKPGTEYEVRVQAVN 77
|
....*..
gi 528959928 970 GDKESDP 976
Cdd:pfam00041 78 GGGEGPP 84
|
|
| GGGWT_bact |
NF040941 |
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ... |
1626-1659 |
3.88e-06 |
|
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.
Pssm-ID: 468872 [Multi-domain] Cd Length: 46 Bit Score: 45.25 E-value: 3.88e-06
10 20 30
....*....|....*....|....*....|....*
gi 528959928 1626 NGDTTSGVYTIYLNNDKTQK-QEVFCDMTSDGGGW 1659
Cdd:NF040941 9 GPSAPSGVYWIDPDGMGGLApFQVYCDMTTDGGGW 43
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1171-1253 |
5.36e-06 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 46.34 E-value: 5.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1171 VTVSEVGWEALKLNWTAPE---GVYEQFLIQVQEPGKEEAAQNLTVPGGLRSVDLPGLKAATHYSITIRGVTRD-FSTAP 1246
Cdd:cd00063 7 LRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGgESPPS 86
|
....*..
gi 528959928 1247 HSVEALT 1253
Cdd:cd00063 87 ESVTVTT 93
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
1438-1808 |
6.75e-06 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 50.54 E-value: 6.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1438 PSSLVTANITDSEALAMWQPAI--APVDNYVISYTGERVpeitRTVSGNTvEYALTNLEPATEYTLRIFA-EKGPQKSST 1514
Cdd:COG3979 6 PTGLTASNVTSSSVSLSWDASTdnVGVTGYDVYRGGDQV----ATVTGLT-AWTVTGLTPGTEYTFTVGAcDAAGNVSAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1515 ITTKFTTDLDSPRDFTATEVQSETALltwrppraSVTGYLLVYESVDGTIKEVVLDPDTTSYSLTDLSPSTYYTARIQAL 1594
Cdd:COG3979 81 SGTSTAMFGGSSTTLGSAEGVADTSG--------NLAASGAFFGVTTPPTPSSTLVVDGTTTVNAAATANGGTGGSGGTT 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1595 NGTLRSKTVKTIFTTSGVLYRFPRDCSQAMLNGDTTSGVYTIYLNNDKTQKQEVFCDMTSDGGGWIVFLRRKNGREDFYR 1674
Cdd:COG3979 153 TIITTGVEGGGGSKTAQSLNAITAAGTAALNGGVVGGADEVLTCSAVKDDGSGGAGAGNTYWALNTLGVSDTPSGTTATG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1675 NWKAYAAGFGDLKEEFWLGLDTLSKITAQGQYELRVDLRDHGESAHAVYDKFSVGDARTRYRLKVEGYSGTAGDSMAYHN 1754
Cdd:COG3979 233 GTVGITSAYGAGVSGNAAVNVNAGFVVGNVGGAAGNTGTTSGTATSDAATNDVGDAAVTGLNDGAANGPTGGYGATGTTV 312
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 528959928 1755 GRSFSTFDKDTDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNSHSQGVNWFHW 1808
Cdd:COG3979 313 AGAAGVGGTKSGTGALGLSGAGGAGAAVSGTATGDDDAGADDSTAGVSGAGSTT 366
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1257-1335 |
1.22e-05 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 45.30 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1257 PEVDNLLVSDATPDGFRLSWTA-DEGVFDSFVLKIRDTKKQSEPLEITLLAPERTR--DITGLREATEYEIELYGISSGR 1333
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPpPDDGITGYIVGYRVEYREEGSEWKEVNVTPSSTsyTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 528959928 1334 RS 1335
Cdd:smart00060 82 EG 83
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
624-695 |
1.79e-05 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 44.91 E-value: 1.79e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528959928 624 SPPKDLVVTEVTEETVNLAWD------NEMRVTEYLIVYTPTHEDglEMQFRVPGDQTSATIRELEPGVEYFIRVFAI 695
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEpppddgITGYIVGYRVEYREEGSE--WKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
894-978 |
2.29e-05 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 44.79 E-value: 2.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 894 DAPRNLRRISQTDNSITLEWRNVK---AAADSYRIKYAPISGGDHAEVEVPRSQQTTTRTTLTGlrPGTEYGIGVSAVKG 970
Cdd:cd00063 2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLK--PGTEYEFRVRAVNG 79
|
....*...
gi 528959928 971 DKESDPAT 978
Cdd:cd00063 80 GGESPPSE 87
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
408-434 |
7.06e-05 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 41.52 E-value: 7.06e-05
10 20
....*....|....*....|....*..
gi 528959928 408 CPRDCSGHGRCVNGQCVCDEGYTGEDC 434
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| FN3 |
cd00063 |
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ... |
1078-1162 |
1.29e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.
Pssm-ID: 238020 [Multi-domain] Cd Length: 93 Bit Score: 42.48 E-value: 1.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 1078 GNLTVTKAGWDGLRLNWTAADQAY---EHFVIQVQEANGVEAAQNLTVPGNLRAVDVPGLKAATPYRVTIHGVIRGYR-T 1153
Cdd:cd00063 5 TNLRVTDVTSTSVTLSWTPPEDDGgpiTGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGEsP 84
|
....*....
gi 528959928 1154 PVLSAEAST 1162
Cdd:cd00063 85 PSESVTVTT 93
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1171-1240 |
1.31e-04 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 42.22 E-value: 1.31e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 528959928 1171 VTVSEVGWEALKLNWTAPE-GVYEQFLIQVQEPGKEEAA--QNLTVPGGLRSVDLPGLKAATHYSITIRGVTR 1240
Cdd:smart00060 7 LRVTDVTSTSVTLSWEPPPdDGITGYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
501-528 |
3.53e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 39.59 E-value: 3.53e-04
10 20
....*....|....*....|....*...
gi 528959928 501 CPGDCSQRGRCVDGRCVCEDGFAGPDCA 528
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| COG3979 |
COG3979 |
Chitodextrinase [Carbohydrate transport and metabolism]; |
987-1055 |
5.99e-04 |
|
Chitodextrinase [Carbohydrate transport and metabolism];
Pssm-ID: 443178 [Multi-domain] Cd Length: 369 Bit Score: 44.38 E-value: 5.99e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 528959928 987 TPKDLRISDPTETSLTLVWQ-----TPVAKFDRYRlnyslpSGQpkEVQLTRDTTSFVLRGLEPGQEYSILLTA 1055
Cdd:COG3979 5 APTGLTASNVTSSSVSLSWDastdnVGVTGYDVYR------GGD--QVATVTGLTAWTVTGLTPGTEYTFTVGA 70
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
594-621 |
9.34e-04 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 38.43 E-value: 9.34e-04
10 20
....*....|....*....|....*...
gi 528959928 594 CPNDCSNWGQCVSGRCVCNEGYTGEDCS 621
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
470-496 |
1.21e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 38.05 E-value: 1.21e-03
10 20
....*....|....*....|....*..
gi 528959928 470 CPHDCHQHGRCVNGMCVCDDAYTGEDC 496
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
411-434 |
1.21e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 37.71 E-value: 1.21e-03
10 20
....*....|....*....|....*.
gi 528959928 411 DCSGHGRCVN--GQCVCDEGYTGEDC 434
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
532-559 |
1.32e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.66 E-value: 1.32e-03
10 20
....*....|....*....|....*...
gi 528959928 532 CPGNCHGRGRCVDGQCVCLEGFTGPDCA 559
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
442-465 |
1.40e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 37.71 E-value: 1.40e-03
10 20
....*....|....*....|....*.
gi 528959928 442 DCHGRGRCVD--GRCECQPGFQGDDC 465
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
894-974 |
1.45e-03 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 39.13 E-value: 1.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528959928 894 DAPRNLRRISQTDNSITLEWRNVK-AAADSYRIKYAPISGGDHAEVEVPRSQQTTTRTTLTGLRPGTEYGIGVSAVKGDK 972
Cdd:smart00060 2 SPPSNLRVTDVTSTSVTLSWEPPPdDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81
|
..
gi 528959928 973 ES 974
Cdd:smart00060 82 EG 83
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
221-248 |
2.09e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 37.28 E-value: 2.09e-03
10 20
....*....|....*....|....*...
gi 528959928 221 CPSDCNDQGKCVDGACVCFEGYSGLDCS 248
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
349-372 |
2.24e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 36.94 E-value: 2.24e-03
10 20
....*....|....*....|....*.
gi 528959928 349 ACHGHGRCD--EGQCVCDEGFAGPDC 372
Cdd:pfam07974 1 ICSGRGTCVnqCGKCVCDSGYQGATC 26
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
439-465 |
2.67e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.89 E-value: 2.67e-03
10 20
....*....|....*....|....*..
gi 528959928 439 CPSDCHGRGRCVDGRCECQPGFQGDDC 465
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
563-590 |
3.04e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.89 E-value: 3.04e-03
10 20
....*....|....*....|....*...
gi 528959928 563 CPGDCHGQGRCVDGQCVCHEGFTGPDCA 590
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| DSL |
pfam01414 |
Delta serrate ligand; This family has been redefined to correspond to the EGF-like domain ... |
394-436 |
3.45e-03 |
|
Delta serrate ligand; This family has been redefined to correspond to the EGF-like domain defined by structure.
Pssm-ID: 460202 Cd Length: 46 Bit Score: 37.22 E-value: 3.45e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 528959928 394 CNDGFTGADCGELQCPRDCS-GHGRC-VNGQCVCDEGYTGEDCGQ 436
Cdd:pfam01414 1 CDENYYGSTCSKFCRPRDDKfGHYTCdANGNKVCLPGWTGPYCDK 45
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
346-373 |
3.70e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 36.51 E-value: 3.70e-03
10 20
....*....|....*....|....*...
gi 528959928 346 CPHACHGHGRCDEGQCVCDEGFAGPDCS 373
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
|
|
| FN3 |
smart00060 |
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ... |
1079-1147 |
4.89e-03 |
|
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.
Pssm-ID: 214495 [Multi-domain] Cd Length: 83 Bit Score: 37.98 E-value: 4.89e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528959928 1079 NLTVTKAGWDGLRLNWTA-ADQAYEHFVIQVQEANGVEAA--QNLTVPGNLRAVDVPGLKAATPYRVTIHGV 1147
Cdd:smart00060 6 NLRVTDVTSTSVTLSWEPpPDDGITGYIVGYRVEYREEGSewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77
|
|
| EGF_2 |
pfam07974 |
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins. |
566-589 |
5.69e-03 |
|
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
Pssm-ID: 400365 Cd Length: 26 Bit Score: 35.79 E-value: 5.69e-03
10 20
....*....|....*....|....*.
gi 528959928 566 DCHGQGRCVD--GQCVCHEGFTGPDC 589
Cdd:pfam07974 1 ICSGRGTCVNqcGKCVCDSGYQGATC 26
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
190-216 |
7.88e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 35.74 E-value: 7.88e-03
10 20
....*....|....*....|....*..
gi 528959928 190 CPGNCHLHGQCLDGQCVCHEGFTGEDC 216
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| EGF_Tenascin |
pfam18720 |
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins. |
377-403 |
7.96e-03 |
|
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
Pssm-ID: 376143 Cd Length: 29 Bit Score: 35.74 E-value: 7.96e-03
10 20
....*....|....*....|....*..
gi 528959928 377 CPSDCHERGRCVDGRCECNDGFTGADC 403
Cdd:pfam18720 2 CPLGCSSRGVCVDGQCICDSEYSGDDC 28
|
|
| |
