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Conserved domains on  [gi|528494691|ref|XP_005172963|]
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ataxin-7-like protein 2a isoform X2 [Danio rerio]

Protein Classification

SCA7 domain-containing protein( domain architecture ID 10550843)

SCA7 domain-containing protein similar to protein Sgf73/Sca7 which is a component of the multihistone acetyltransferase complexes SAGA and SILK

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SCA7 pfam08313
SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component ...
 188-249 1.07e-19

SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component of the multihistone acetyltransferase complexes SAGA and SILK. This domain is also found in Ataxin-7, a human protein which in its polyglutamine expanded pathological form, is responsible for the neurodegenerative disease spinocerebellar ataxia 7 (SCA7). Ataxin-7 is an integral component of the mammalian SAGA-like complexes, the TATA-binding protein-free TAF-containing complex (TFTC) and the SPT3/TAF9/GCN5 acetyltransferase complex (STAGA). This domain is a minimal domain in ataxin-7-like proteins that is required for interaction with TFTC/STAGA subunits and is conserved highly through evolution. The domain contains a conserved Cys(3)His motif that binds zinc, thus indicating this to be a new zinc-binding domain.


:

Pssm-ID: 462422  Cd Length: 61  Bit Score: 83.04  E-value: 1.07e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528494691  188 HKMVSKKECDLDKHCGVLDTErKKVCTRLLTCNIHSIHQRRKVQGRSKNFDQLVAELKMSSK 249
Cdd:pfam08313   1 KKPKAKRPVDVDKQCGVILPN-GGPCTRSLTCKTHSMGAKRAVPGRSKPFDVLLAEYQKKNQ 61
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 63-597 2.03e-06

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.48  E-value: 2.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691   63 GHTPPSHGATASWSGRNQNVGPPRASPQSP---ATPPQFRHSKPPKDGVWHSPSNSSNSahsesavfkqPPPIEPTRSSP 139
Cdd:PHA03247 2549 GDPPPPLPPAAPPAAPDRSVPPPRPAPRPSepaVTSRARRPDAPPQSARPRAPVDDRGD----------PRGPAPPSPLP 2618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  140 PPAHR-DPPWPHGGPSPNRLPPAAERPQSQRGEAASAPVPSghlrgtkthkmvskkecdldkhcgvldterkkvctRLlt 218
Cdd:PHA03247 2619 PDTHApDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPG-----------------------------------RV-- 2661

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  219 cnihSIHQRRKVQGRSKNFDQlvaelkMSSKARERVSQAPESSSAPSVSPEPPRDTPAPpscrRPLTNSPAFRTPVSSES 298
Cdd:PHA03247 2662 ----SRPRRARRLGRAAQASS------PPQRPRRRAARPTVGSLTSLADPPPPPPTPEP----APHALVSATPLPPGPAA 2727

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  299 IEEDKTHLEESSTRAHSPLTQAHISGDESEGETNEEpadwhSTPWHPKPAALCSFGShslghgvftfDRRLhhLRSAMSA 378
Cdd:PHA03247 2728 ARQASPALPAAPAPPAVPAGPATPGGPARPARPPTT-----AGPPAPAPPAAPAAGP----------PRRL--TRPAVAS 2790

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  379 MVESHLSAhlwkkipqasdPQSQSPQAKPAAVPASPSSISQHSKPRAGSHNTTSSLKTSFYSSHGPGKEPNPQSSSTSka 458
Cdd:PHA03247 2791 LSESRESL-----------PSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA-- 2857

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  459 yaqsenSGSSKLGRSPSQSGPGRPKNP-------VGRPSKQQMRLR------ESDRTPTPDAAALRKRKASFEDSDSAVS 525
Cdd:PHA03247 2858 ------PGGDVRRRPPSRSPAAKPAAParppvrrLARPAVSRSTESfalppdQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  526 PDKncvPQNKSRPLISKTPPSASHGQT--------NGSLSPGSKARPSdSHSPSSWAFKRTHQSAPDSRGLDSGLRVSSF 597
Cdd:PHA03247 2932 PPP---PPPRPQPPLAPTTDPAGAGEPsgavpqpwLGALVPGRVAVPR-FRVPQPAPSREAPASSTPPLTGHSLSRVSSW 3007
 
Name Accession Description Interval E-value
SCA7 pfam08313
SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component ...
 188-249 1.07e-19

SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component of the multihistone acetyltransferase complexes SAGA and SILK. This domain is also found in Ataxin-7, a human protein which in its polyglutamine expanded pathological form, is responsible for the neurodegenerative disease spinocerebellar ataxia 7 (SCA7). Ataxin-7 is an integral component of the mammalian SAGA-like complexes, the TATA-binding protein-free TAF-containing complex (TFTC) and the SPT3/TAF9/GCN5 acetyltransferase complex (STAGA). This domain is a minimal domain in ataxin-7-like proteins that is required for interaction with TFTC/STAGA subunits and is conserved highly through evolution. The domain contains a conserved Cys(3)His motif that binds zinc, thus indicating this to be a new zinc-binding domain.


Pssm-ID: 462422  Cd Length: 61  Bit Score: 83.04  E-value: 1.07e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528494691  188 HKMVSKKECDLDKHCGVLDTErKKVCTRLLTCNIHSIHQRRKVQGRSKNFDQLVAELKMSSK 249
Cdd:pfam08313   1 KKPKAKRPVDVDKQCGVILPN-GGPCTRSLTCKTHSMGAKRAVPGRSKPFDVLLAEYQKKNQ 61
PHA03247 PHA03247
large tegument protein UL36; Provisional
 63-597 2.03e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.48  E-value: 2.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691   63 GHTPPSHGATASWSGRNQNVGPPRASPQSP---ATPPQFRHSKPPKDGVWHSPSNSSNSahsesavfkqPPPIEPTRSSP 139
Cdd:PHA03247 2549 GDPPPPLPPAAPPAAPDRSVPPPRPAPRPSepaVTSRARRPDAPPQSARPRAPVDDRGD----------PRGPAPPSPLP 2618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  140 PPAHR-DPPWPHGGPSPNRLPPAAERPQSQRGEAASAPVPSghlrgtkthkmvskkecdldkhcgvldterkkvctRLlt 218
Cdd:PHA03247 2619 PDTHApDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPG-----------------------------------RV-- 2661

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  219 cnihSIHQRRKVQGRSKNFDQlvaelkMSSKARERVSQAPESSSAPSVSPEPPRDTPAPpscrRPLTNSPAFRTPVSSES 298
Cdd:PHA03247 2662 ----SRPRRARRLGRAAQASS------PPQRPRRRAARPTVGSLTSLADPPPPPPTPEP----APHALVSATPLPPGPAA 2727

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  299 IEEDKTHLEESSTRAHSPLTQAHISGDESEGETNEEpadwhSTPWHPKPAALCSFGShslghgvftfDRRLhhLRSAMSA 378
Cdd:PHA03247 2728 ARQASPALPAAPAPPAVPAGPATPGGPARPARPPTT-----AGPPAPAPPAAPAAGP----------PRRL--TRPAVAS 2790

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  379 MVESHLSAhlwkkipqasdPQSQSPQAKPAAVPASPSSISQHSKPRAGSHNTTSSLKTSFYSSHGPGKEPNPQSSSTSka 458
Cdd:PHA03247 2791 LSESRESL-----------PSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA-- 2857

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  459 yaqsenSGSSKLGRSPSQSGPGRPKNP-------VGRPSKQQMRLR------ESDRTPTPDAAALRKRKASFEDSDSAVS 525
Cdd:PHA03247 2858 ------PGGDVRRRPPSRSPAAKPAAParppvrrLARPAVSRSTESfalppdQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  526 PDKncvPQNKSRPLISKTPPSASHGQT--------NGSLSPGSKARPSdSHSPSSWAFKRTHQSAPDSRGLDSGLRVSSF 597
Cdd:PHA03247 2932 PPP---PPPRPQPPLAPTTDPAGAGEPsgavpqpwLGALVPGRVAVPR-FRVPQPAPSREAPASSTPPLTGHSLSRVSSW 3007
 
Name Accession Description Interval E-value
SCA7 pfam08313
SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component ...
 188-249 1.07e-19

SCA7, zinc-binding domain; This domain is found in the protein Sgf73/Sca7 which is a component of the multihistone acetyltransferase complexes SAGA and SILK. This domain is also found in Ataxin-7, a human protein which in its polyglutamine expanded pathological form, is responsible for the neurodegenerative disease spinocerebellar ataxia 7 (SCA7). Ataxin-7 is an integral component of the mammalian SAGA-like complexes, the TATA-binding protein-free TAF-containing complex (TFTC) and the SPT3/TAF9/GCN5 acetyltransferase complex (STAGA). This domain is a minimal domain in ataxin-7-like proteins that is required for interaction with TFTC/STAGA subunits and is conserved highly through evolution. The domain contains a conserved Cys(3)His motif that binds zinc, thus indicating this to be a new zinc-binding domain.


Pssm-ID: 462422  Cd Length: 61  Bit Score: 83.04  E-value: 1.07e-19
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528494691  188 HKMVSKKECDLDKHCGVLDTErKKVCTRLLTCNIHSIHQRRKVQGRSKNFDQLVAELKMSSK 249
Cdd:pfam08313   1 KKPKAKRPVDVDKQCGVILPN-GGPCTRSLTCKTHSMGAKRAVPGRSKPFDVLLAEYQKKNQ 61
PHA03247 PHA03247
large tegument protein UL36; Provisional
 63-597 2.03e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.48  E-value: 2.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691   63 GHTPPSHGATASWSGRNQNVGPPRASPQSP---ATPPQFRHSKPPKDGVWHSPSNSSNSahsesavfkqPPPIEPTRSSP 139
Cdd:PHA03247 2549 GDPPPPLPPAAPPAAPDRSVPPPRPAPRPSepaVTSRARRPDAPPQSARPRAPVDDRGD----------PRGPAPPSPLP 2618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  140 PPAHR-DPPWPHGGPSPNRLPPAAERPQSQRGEAASAPVPSghlrgtkthkmvskkecdldkhcgvldterkkvctRLlt 218
Cdd:PHA03247 2619 PDTHApDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPG-----------------------------------RV-- 2661

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  219 cnihSIHQRRKVQGRSKNFDQlvaelkMSSKARERVSQAPESSSAPSVSPEPPRDTPAPpscrRPLTNSPAFRTPVSSES 298
Cdd:PHA03247 2662 ----SRPRRARRLGRAAQASS------PPQRPRRRAARPTVGSLTSLADPPPPPPTPEP----APHALVSATPLPPGPAA 2727

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  299 IEEDKTHLEESSTRAHSPLTQAHISGDESEGETNEEpadwhSTPWHPKPAALCSFGShslghgvftfDRRLhhLRSAMSA 378
Cdd:PHA03247 2728 ARQASPALPAAPAPPAVPAGPATPGGPARPARPPTT-----AGPPAPAPPAAPAAGP----------PRRL--TRPAVAS 2790

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  379 MVESHLSAhlwkkipqasdPQSQSPQAKPAAVPASPSSISQHSKPRAGSHNTTSSLKTSFYSSHGPGKEPNPQSSSTSka 458
Cdd:PHA03247 2791 LSESRESL-----------PSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA-- 2857

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  459 yaqsenSGSSKLGRSPSQSGPGRPKNP-------VGRPSKQQMRLR------ESDRTPTPDAAALRKRKASFEDSDSAVS 525
Cdd:PHA03247 2858 ------PGGDVRRRPPSRSPAAKPAAParppvrrLARPAVSRSTESfalppdQPERPPQPQAPPPPQPQPQPPPPPQPQP 2931

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  526 PDKncvPQNKSRPLISKTPPSASHGQT--------NGSLSPGSKARPSdSHSPSSWAFKRTHQSAPDSRGLDSGLRVSSF 597
Cdd:PHA03247 2932 PPP---PPPRPQPPLAPTTDPAGAGEPsgavpqpwLGALVPGRVAVPR-FRVPQPAPSREAPASSTPPLTGHSLSRVSSW 3007
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 50-180 1.53e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.98  E-value: 1.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  50 STPPPSQQQRPRHGHTPPSHGATASWSGRNQNVGPPRASPQSPATPPQFRHSKPPKDGVWHSPSNSSNSAHSESAVFKQP 129
Cdd:PRK07764 599 GPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAP 678

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 528494691 130 -PPIEPTRSSPPPAHRDPPWPHGGPSPnRLPPAAERPQSQRGEAASAPVPSG 180
Cdd:PRK07764 679 aAPPPAPAPAAPAAPAGAAPAQPAPAP-AATPPAGQADDPAAQPPQAAQGAS 729
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 63-179 2.68e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.39  E-value: 2.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691   63 GHTPPSHGATASWSGRNQNVGPPRASPQSPATPPQFRHSK--PPKDGVWHSPSNSSNSAHSE-------SAVFKQPPPIE 133
Cdd:PHA03307  258 PRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSpsPSSPGSGPAPSSPRASSSSSssresssSSTSSSSESSR 337

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 528494691  134 PTRSSPPPAHRDPPWPHGGPSPNRLPPAAERPQSQRGEAASAPVPS 179
Cdd:PHA03307  338 GAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAG 383
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 50-178 2.71e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.21  E-value: 2.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  50 STPPPSQQQRPRHGHTPPSHGATAswsgrnqnvGPPRASPQSPATPPQFRHSKPPKDGVWHSPSNSSNSAHSESAVFKQP 129
Cdd:PRK07764 617 APAAPAAPAAPAPAGAAAAPAEAS---------AAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAP 687

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 528494691 130 --PPIEPTRSSPPPAHRDPPWPHGGPSPNRL--PPAAERPQSQRGEAASAPVP 178
Cdd:PRK07764 688 aaPAAPAGAAPAQPAPAPAATPPAGQADDPAaqPPQAAQGASAPSPAADDPVP 740
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 67-180 5.70e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.16  E-value: 5.70e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  67 PSHGATASWSGRNQNVGPPRASPQSPATPPQfrhskPPKDGVWHSPSNSSNSAHSESavfkqPPPIEPTRSSPPPAHRDP 146
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQ-----AAAAPAPAAAPAAAASAPAAP-----PAAAPPAPVAAPAAAAPA 435

                         90       100       110
                 ....*....|....*....|....*....|....
gi 528494691 147 PWPHGGPSPNRLPPAAERPQSQRGEAASAPVPSG 180
Cdd:PRK14951 436 AAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPE 469
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
393-571 6.45e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.94  E-value: 6.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 393 PQASDPQSQSPQAKPAAVPAS-PSSISQHSKPRAGSHNTTSSLKTSFYSSHGPGKEPNPQSSSTSKAYAQSENSGSSKLG 471
Cdd:PRK12323 392 PAAAAPAPAAPPAAPAAAPAAaAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRP 471

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 472 RSPSQSGPGRPKNPVGRPSKQQMRLRESDRTP-TPDAAALRKRKASFEDSDSAVSPDKNCVPQNKSRPLISKTPPSASHG 550
Cdd:PRK12323 472 VAAAAAAAPARAAPAAAPAPADDDPPPWEELPpEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAP 551

                        170       180
                 ....*....|....*....|.
gi 528494691 551 QTNGSLSPGSKARPSDSHSPS 571
Cdd:PRK12323 552 RAAAATEPVVAPRPPRASASG 572
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 104-184 6.98e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 42.62  E-value: 6.98e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 104 PKDGVWHSPSNSSNSAHSESAVFKQPPPIEPTRSSPPPAHRDP---PWPHGGPSPNRLPPAAERPQSQRGEAASAPVPSG 180
Cdd:PRK14954 376 NDGGVAPSPAGSPDVKKKAPEPDLPQPDRHPGPAKPEAPGARPaelPSPASAPTPEQQPPVARSAPLPPSPQASAPRNVA 455


                 ....
gi 528494691 181 HLRG 184
Cdd:PRK14954 456 SGKP 459
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 27-181 7.11e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 7.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  27 PQAFEKHCERRHGPLGKLYAHLRSTPP---PSQQQRPRHGHTPPSHGATASWSGRNQNVGPPRASPQS--PATPPQFRHS 101
Cdd:PRK07764 636 PAEASAAPAPGVAAPEHHPKHVAVPDAsdgGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPapAATPPAGQAD 715

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 102 KPPKDGVWHSPSNSSNSAHSESAVFKQP-PPIEPTRSSPPPAHRDPPWPHGGPSPNRLPPAAERPQSQR--GEAASAPVP 178
Cdd:PRK07764 716 DPAAQPPQAAQGASAPSPAADDPVPLPPePDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEmaEDDAPSMDD 795


                 ...
gi 528494691 179 SGH 181
Cdd:PRK07764 796 EDR 798
PHA03247 PHA03247
large tegument protein UL36; Provisional
 52-182 7.21e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 7.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691   52 PPPSQQQRPRHGHTPPSH-----GATASWSGRNQNVGPPRASPQSPATPPQFRHSKPPKDGVWHSPSnSSNSAHSESAVF 126
Cdd:PHA03247 2830 PPTSAQPTAPPPPPGPPPpslplGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTE-SFALPPDQPERP 2908

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 528494691  127 KQPPPIEPTRSSPPPAHRDPPWPHGGPSPNRLPPAAERPQSQRGEAASAPVPSGHL 182
Cdd:PHA03247 2909 PQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWL 2964
PHA03247 PHA03247
large tegument protein UL36; Provisional
 259-547 7.84e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 7.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  259 ESSSAPSVSPEPPRDTPAPPSC--RRPLTNSPAFRTPVSSESIEEDKTHLEESSTRAHSPLTQAhisgDESEGETNEEPA 336
Cdd:PHA03247 2542 ELASDDAGDPPPPLPPAAPPAApdRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDR----GDPRGPAPPSPL 2617

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  337 DWHSTPWHPKPAALCSFGSHSLGHGVFTFDRRLHHLRSAMSAMVESHLSAHLWKKIPQASDP-QSQSPQAKPAAVPASPS 415
Cdd:PHA03247 2618 PPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPpQRPRRRAARPTVGSLTS 2697

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  416 SISQHSKPRA---GSHNTTSSLKTSFYSSHGPGKEPNPQSSSTSKAYAQSE--NSGSSKLGRSPSQSGPGRPKNPVGRPS 490
Cdd:PHA03247 2698 LADPPPPPPTpepAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPatPGGPARPARPPTTAGPPAPAPPAAPAA 2777

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 528494691  491 KQQMRLRESDRTPTPDAAALRKRKASFEDSDSAVSPDKNCVPQNKSRPLISKTPPSA 547
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSA 2834
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 257-556 1.06e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.47  E-value: 1.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  257 APESSSAPSVSPEPPRDTPAPPSCRRPLTNSPAFRTPVSSES----IEEDKTHLEESSTRAHSPLTQAHISGDESEGETN 332
Cdd:PHA03307  149 AASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPaeppPSTPPAAASPRPPRRSSPISASASSPAPAPGRSA 228

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  333 EEPADWHSTPWHPKPAALCSFGSHSLGHGVftfdrrlhhlRSAMSAMVESHLSAHLWKkiPQASDPQSQSPQAKPAAVPA 412
Cdd:PHA03307  229 ADDAGASSSDSSSSESSGCGWGPENECPLP----------RPAPITLPTRIWEASGWN--GPSSRPGPASSSSSPRERSP 296

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  413 SPSSisqhSKPRAGSHNTTSSLKTSFYSSHgpgkepnpqSSSTSKAYAQSENSGS--SKLGRSPSQSG-PGRPKNPVGRP 489
Cdd:PHA03307  297 SPSP----SSPGSGPAPSSPRASSSSSSSR---------ESSSSSTSSSSESSRGaaVSPGPSPSRSPsPSRPPPPADPS 363

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528494691  490 SKQQM-RLRESDRTPTPDAAALRKRKASFEDSDSAVSPDK-NCVPQNKSRPLISKTPPSASHGQTNGSL 556
Cdd:PHA03307  364 SPRKRpRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDAtGRFPAGRPRPSPLDAGAASGAFYARYPL 432
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 398-633 1.07e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 42.37  E-value: 1.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 398 PQSQSPQAKPAAVPASPSSISQHSKPRAGSHNTTSSLKTSFYSSHGPGKEPNPqssstSKAYAQSENSGSSKLGRSPSQS 477
Cdd:PTZ00449 511 PEGPEASGLPPKAPGDKEGEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGP-----AKEHKPSKIPTLSKKPEFPKDP 585

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 478 -GPGRPKNPvgRPSKQQMRLRESDRTPTPDAAALRKRKASFEDSDSAVSPDKNCVPQNKSRPLISKTPPSASHGQTNGS- 555
Cdd:PTZ00449 586 kHPKDPEEP--KKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSp 663

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 556 ---LSPGSKARPSDSHSPSSWAFKRTHQSAPDSRGLDSGLRvssfdhKSLGKKRKSSGSSPPSKPHRLPTSPHSGFYTWK 632
Cdd:PTZ00449 664 kppFDPKFKEKFYDDYLDAAAKSKETKTTVVLDESFESILK------ETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIG 737


                 .
gi 528494691 633 E 633
Cdd:PTZ00449 738 D 738
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 35-463 1.37e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.90  E-value: 1.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  35 ERRHGPLGKLYAhlRSTPPPSQQQRPRHGHTPPSHGATASWSGRNQNVGPPRASPQSPATPPQFRHSKPPKDGVWHSPSN 114
Cdd:PRK07764 382 ERRLGVAGGAGA--PAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPA 459

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 115 SSNSAHSESAVFKQPPPIEPTRSSPPPAHrdppwphggpspnrlPPAAERPQSQRGEAASAPVPSGHLRG------TKTH 188
Cdd:PRK07764 460 AAPSAQPAPAPAAAPEPTAAPAPAPPAAP---------------APAAAPAAPAAPAAPAGADDAATLRErwpeilAAVP 524

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 189 KMVSKKECDLDKHCGVLDTERKKVctrLLTCNIHSIHQRRKVQGRSKNFDQLVAElKMSSKARERVSQAPESSSAPSVSP 268
Cdd:PRK07764 525 KRSRKTWAILLPEATVLGVRGDTL---VLGFSTGGLARRFASPGNAEVLVTALAE-ELGGDWQVEAVVGPAPGAAGGEGP 600

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 269 EPPRDTPAPPSCRRPlTNSPAFRTPVSSESIEEDKTHLEESSTRAHSPLTQAHISGDESEGETNEEPADWHSTPWHPKPA 348
Cdd:PRK07764 601 PAPASSGPPEEAARP-AAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPA 679

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 349 ALCSFGSHSLGHGVFTFDRRLHHLRSAMSAMVEshlsahlwkkipQASDPQSQSPQAKPAAVPASPSSISQHSKPRAgSH 428
Cdd:PRK07764 680 APPPAPAPAAPAAPAGAAPAQPAPAPAATPPAG------------QADDPAAQPPQAAQGASAPSPAADDPVPLPPE-PD 746

                        410       420       430
                 ....*....|....*....|....*....|....*
gi 528494691 429 NTTSSLKTSFYSSHGPGKEPNPQSSSTSKAYAQSE 463
Cdd:PRK07764 747 DPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE 781
dnaA PRK14086
chromosomal replication initiator protein DnaA;
38-180 2.23e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 40.96  E-value: 2.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  38 HGPLGKLYAHLRSTPP--PSQQQRPRHGHTPPshgATASWSGRNQNVGPPRASPQSPAT---PPQFRHSKPPKDGVWHSP 112
Cdd:PRK14086 129 RPPGLPRQDQLPTARPayPAYQQRPEPGAWPR---AADDYGWQQQRLGFPPRAPYASPAsyaPEQERDREPYDAGRPEYD 205

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 528494691 113 SNSSNSAHSESAvFKQPPPIEPTRSSPPPA----HRDPPWPHGGPSPNRLPPAAERPQSQRGEAASAPVPSG 180
Cdd:PRK14086 206 QRRRDYDHPRPD-WDRPRRDRTDRPEPPPGaghvHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPGE 276
PHA03378 PHA03378
EBNA-3B; Provisional
 49-178 2.44e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 41.21  E-value: 2.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  49 RSTPPPSQ--QQRPRHGHTPPSHGATASWSGRNQNVGP-PRASPQSPATPPQFRHSKPPKDGVWHSPSNSSNSAHSESAV 125
Cdd:PHA03378 612 QSHIPETSapRQWPMPLRPIPMRPLRMQPITFNVLVFPtPHQPPQVEITPYKPTWTQIGHIPYQPSPTGANTMLPIQWAP 691

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 528494691 126 FK-QPPPIEPTRSSPP---PAHRDPPWPHGGPSPnrlPPAAERPQSQRGEAASAPVP 178
Cdd:PHA03378 692 GTmQPPPRAPTPMRPPaapPGRAQRPAAATGRAR---PPAAAPGRARPPAAAPGRAR 745
PHA03247 PHA03247
large tegument protein UL36; Provisional
 49-516 3.70e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 3.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691   49 RSTPPPSQQQRP------RHGHTPPSHGATASWSGRNQNVGPPRASPQSPATPPQFRHSKPPKDgvwhSPSNSSNSAHSE 122
Cdd:PHA03247 2566 RSVPPPRPAPRPsepavtSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPP----SPSPAANEPDPH 2641

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  123 SAVFKQPPPIEPTRSSPPPAHRdppwPHGGPSPNRLPPAAERPQSQRGEAASAPVPSgHLRGTKTHKMVSKKEcdldkhc 202
Cdd:PHA03247 2642 PPPTVPPPERPRDDPAPGRVSR----PRRARRLGRAAQASSPPQRPRRRAARPTVGS-LTSLADPPPPPPTPE------- 2709

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  203 gvldtERKKVCTRLLTCNIHSIHQRRKVQGRSKNFDQLVAELKMSSKARERVSQAPESSSAPSvSPEPPRDTPAPPSCRR 282
Cdd:PHA03247 2710 -----PAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPP-APAPPAAPAAGPPRRL 2783

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  283 PltnspafRTPVSSESIEEDKTHLEESSTRAHSPLTQAHISGDESEGETNEEPADWHSTPWHPKPAALCSFGSHSLGHGV 362
Cdd:PHA03247 2784 T-------RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSV 2856

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  363 F---TFDRRLHHLRSAMSAMVESHLSAhlwKKIPQASDPQSQSPQAKPAAVPASPSSISQHSKPRAGSHNTTSSLKTsfy 439
Cdd:PHA03247 2857 ApggDVRRRPPSRSPAAKPAAPARPPV---RRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQ--- 2930

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  440 sshgPGKEPNPQSSSTSKAYAQSENSGSSKLGRSPSQSG---PGRPKNPVGRPSKQqmrlRESDRTPTPDAAALRKRKAS 516
Cdd:PHA03247 2931 ----PPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGalvPGRVAVPRFRVPQP----APSREAPASSTPPLTGHSLS 3002
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 393-566 4.00e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 4.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 393 PQASDPQSQSPQAKPAAVPASPSSISQHSKPRAGSHNTTSSLKTSFYSSHGPGKEPNP--QSSSTSKAYAQSENSGSSKL 470
Cdd:PRK07764 615 PAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKagGAAPAAPPPAPAPAAPAAPA 694

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691 471 GRSPSQSGPGRPKNPVGRPSkqqmrlrESDRTPTPDAAALRKRKASFEDSDSAVSPDKNCVPQNKSRPlisktPPSASHG 550
Cdd:PRK07764 695 GAAPAQPAPAPAATPPAGQA-------DDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAP-----AQPPPPP 762

                        170
                 ....*....|....*.
gi 528494691 551 QTNGSLSPGSKARPSD 566
Cdd:PRK07764 763 APAPAAAPAAAPPPSP 778
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 27-349 5.09e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.15  E-value: 5.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691   27 PQAFEKHCERRHGPLGKLYAHLRSTPPPSQQQRPRHGHTPPSHGATASWSGRNQNVGPPRASPQSPATPPQFRHSKPPKD 106
Cdd:PHA03307   75 PGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPA 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  107 GVWHSPSNSSNSAHSESAVFKQPPPIEPTRSSPPPAHRDPPwphgGPSPNRLPPAAERPQSQRGEAASAPVPSGhlrgtk 186
Cdd:PHA03307  155 AGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPP----STPPAAASPRPPRRSSPISASASSPAPAP------ 224

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  187 thkmvsKKECDLDKHCGVLDterkkvctrlltcNIHSIHQRRKVQGRSKNFDQLVAELKMSSKARERVSQAPESSSAPSV 266
Cdd:PHA03307  225 ------GRSAADDAGASSSD-------------SSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPA 285

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  267 SPE-PPRDTPAPPSCRRPLTNSPAFRTPVSSESIEEDKTHLEESSTRAHSPLTQA-HISGDESEGETNEEPADWHSTPWH 344
Cdd:PHA03307  286 SSSsSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAvSPGPSPSRSPSPSRPPPPADPSSP 365


                  ....*
gi 528494691  345 PKPAA 349
Cdd:PHA03307  366 RKRPR 370
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 53-178 5.30e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.08  E-value: 5.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  53 PPSQQQRPRHGHTPPShGATASWSGRNQNVGPPRASPQSPATPPQFRHskppkdgvwHSPSNSSNSAHSESAVFKQPPPI 132
Cdd:PRK14951 393 PVAQAAAAPAPAAAPA-AAASAPAAPPAAAPPAPVAAPAAAAPAAAPA---------AAPAAVALAPAPPAQAAPETVAI 462

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 528494691 133 ePTRSSPPPAHRDPPWPHGGPspnrlPPAAERPQSQRGEAASAPVP 178
Cdd:PRK14951 463 -PVRVAPEPAVASAAPAPAAA-----PAAARLTPTEEGDVWHATVQ 502
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 393-596 5.41e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.15  E-value: 5.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  393 PQASDPQSQSPQakPAAVPASPSSISQHSKPRAGSHNTTSSLKTSFYSShGPGKEPNPQSSSTSKAYAQSENSGSSKLGR 472
Cdd:PHA03307  111 PSSPDPPPPTPP--PASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGA-SPAAVASDAASSRQAALPLSSPEETARAPS 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  473 SPSQSGPGRPKNPVGRPSKQQMRLRESDRTPTPDAAALR----KRKASFEDSDSAVSPDKNCVPQNKS-RPLISKTPPSA 547
Cdd:PHA03307  188 SPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRsaadDAGASSSDSSSSESSGCGWGPENECpLPRPAPITLPT 267

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 528494691  548 SHGQTNGSLSPGSKARPSDSHSPSSWAFKRTHQSAPDSRGLDSGLRVSS 596
Cdd:PHA03307  268 RIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASS 316
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
52-179 6.80e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 39.47  E-value: 6.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  52 PPPSQQQRPRHGHTPPSHGATASWSGRNQNVGPPRASPQS-------PATPPQFRHSKPPKDGVWHSPSNSSNSAHSESA 124
Cdd:PRK12323 413 AAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPapaaapaAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPA 492

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528494691 125 VFKQPPPIE--PTRSSPPPAHRDPPWP----HGGPSPNRLPPAAERPqSQRGEAASAPVPS 179
Cdd:PRK12323 493 DDDPPPWEElpPEFASPAPAQPDAAPAgwvaESIPDPATADPDDAFE-TLAPAPAAAPAPR 552
dnaA PRK14086
chromosomal replication initiator protein DnaA;
50-181 7.16e-03

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 39.42  E-value: 7.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  50 STPPPSQQ-----QRPRHGHTP-PSHGATASwSGRNQNVGPPRASPQSPATPPQFRHSKPPkdGVWHSPSNSSN-----S 118
Cdd:PRK14086  96 APPPPHARrtsepELPRPGRRPyEGYGGPRA-DDRPPGLPRQDQLPTARPAYPAYQQRPEP--GAWPRAADDYGwqqqrL 172

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 528494691 119 AHSESAVFKQP--PPIEPTRSSPPPAHRDPPWPHGGPSPNRLPPAAERPQSQRGEAASAPVPSGH 181
Cdd:PRK14086 173 GFPPRAPYASPasYAPEQERDREPYDAGRPEYDQRRRDYDHPRPDWDRPRRDRTDRPEPPPGAGH 237
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 50-163 8.08e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 39.31  E-value: 8.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528494691  50 STPPPSQQQRPRHGHTPPSHGATASwsgrnqnVGPPRASPQSPATPPQFRHSKP--------PKDGVWHSPSNSSNSAHS 121
Cdd:PRK14951 379 KTPARPEAAAPAAAPVAQAAAAPAP-------AAAPAAAASAPAAPPAAAPPAPvaapaaaaPAAAPAAAPAAVALAPAP 451

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 528494691 122 ESAVFKQPPPIePTRSSPPPAHRDPPWPH-GGPSPNRLPPAAE 163
Cdd:PRK14951 452 PAQAAPETVAI-PVRVAPEPAVASAAPAPaAAPAAARLTPTEE 493
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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