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Conserved domains on  [gi|528471437|ref|XP_005171336|]
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tenascin-R isoform X2 [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FReD cd00087
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ...
 1037-1247 1.43e-117

Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.


:

Pssm-ID: 238040 [Multi-domain]  Cd Length: 215  Bit Score: 364.25  E-value: 1.43e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437 1037 PTPQNCAQHLLNGETLGGIYTIYVNRDlSQGVQVYCDMTTDGGGWIVFQRRQNGLTDFSRKWTDYKIGFGNLEDEFWLGL 1116
Cdd:cd00087     1 PLPRDCSEVLQRGGRTSGVYTIQPPGS-NEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437 1117 DNIHKIAAQGRYELRIDMKDG-QESVYANYDRFSIGDSKSLYKLRIGEYNGTAGDSLSYHQSRPFSTKDKDNDIAVTNCA 1195
Cdd:cd00087    80 EKIHLLTSQGPYELRIDLEDWeGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 528471437 1196 LSYKGAWWYKNCHRANLNGKYGESRH----SQGINWYHWKGHEFSIPFVEMKMRPF 1247
Cdd:cd00087   160 ESYSGGWWYNSCHASNLNGRYYSGGHrneyDNGINWATWKGSTYSLKFTEMKIRPK 215
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
506-941 1.28e-21

Fibronectin type 3 domain [General function prediction only];


:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 100.85  E-value: 1.28e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  506 IVRDISDTVAFVEWSPPKAKVDQIILRYGLVGVEGPKTTFRLQPTLSQYSLQVLRPGSTYEVSVSGVRNGTES----GVI 581
Cdd:COG3401   146 GLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESapsnEVS 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  582 STEFTTEIDAPKNLRVLSKTSISLELEWD-NSEADVEGYSVVYSTLAGDQYDKVivprNDGPSTKTTLNELMPGTEYGIG 660
Cdd:COG3401   226 VTTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKV----ATVTTTSYTDTGLTNGTTYYYR 301

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  661 ISAVLGAN----QSTPATMNARTGL-DVPLDLTVTASTDNTITLLWGTVQGP-IDHYRVTY-TSSSGVTTELTVPKDVTT 733
Cdd:COG3401   302 VTAVDAAGnesaPSNVVSVTTDLTPpAAPSGLTATAVGSSSITLSWTASSDAdVTGYNVYRsTSGGGTYTKIAETVTTTS 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  734 TTLTSLEPGTKYTITVAA--QRGRQQSTAATIDAFTGMDPPRDITVLYVTEesVTITWIQPLALFDYYRMSY-QSSKGRM 810
Cdd:COG3401   382 YTDTGLTPGTTYYYKVTAvdAAGNESAPSEEVSATTASAASGESLTASVDA--VPLTDVAGATAAASAASNPgVSAAVLA 459

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  811 DSVVIDNDINNYTLTSLHPATEYEIKLNAVRGSQESKVITTTVFTAMDMPAELTALNVTPQGALLRWNPPASSVDNYVLT 890
Cdd:COG3401   460 DGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGSLVGGSGASSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVG 539

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 528471437  891 VTRNQVTADTFLVEGNKQEYQLSQLIPSTTYSVALYATKGPLTSGTVISNF 941
Cdd:COG3401   540 ASTGDVLITDLVSLTTSASSSVSGAGLGSGNLYLITTLGGSLLTTTSTNTN 590
fn3 pfam00041
Fibronectin type III domain;
323-401 1.12e-14

Fibronectin type III domain;


:

Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 70.52  E-value: 1.12e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   323 PPMNLRVRGVSENTIDLQWEGP----AILTDYLITYAPTTPGGVQLEMRVPGNVTNITIKGLNPGLEYNVNVYAVIDNII 398
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPPpdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 528471437   399 SSP 401
Cdd:pfam00041   82 GPP 84
fn3 pfam00041
Fibronectin type III domain;
946-1018 7.55e-11

Fibronectin type III domain;


:

Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 59.35  E-value: 7.55e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528471437   946 DAPQNLTASEINHRSALISWQPP---IADIDNYMLTYKAADGSR--KELILDAEDTWIRLEGLAETTEYTVRLQAARG 1018
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
fn3 pfam00041
Fibronectin type III domain;
411-490 3.49e-10

Fibronectin type III domain;


:

Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 57.81  E-value: 3.49e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   411 SNPDGLLFKSIMETSVEVQWQPLDYL---FDGWEISFIPKD-NDGGMTAQLPSTITSFHQTGLKPGEEYTVNLVALKDQG 486
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPDGngpITGYEVEYRPKNsGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....
gi 528471437   487 RSLP 490
Cdd:pfam00041   81 EGPP 84
EGF_Tenascin super family cl46594
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 230-257 1.07e-07

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


The actual alignment was detected with superfamily member pfam18720:

Pssm-ID: 480934  Cd Length: 29  Bit Score: 48.83  E-value: 1.07e-07
                           10        20
                   ....*....|....*....|....*...
gi 528471437   230 CPSDCSDRGLCIDGECVCEEAFAGEDCS 257
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
C_rich_MXAN6577 super family cl49352
MXAN_6577-like cysteine-rich domain;
234-318 6.68e-07

MXAN_6577-like cysteine-rich domain;


The actual alignment was detected with superfamily member NF041328:

Pssm-ID: 469225 [Multi-domain]  Cd Length: 145  Bit Score: 50.14  E-value: 6.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  234 CSDRG-LCIDGECVCEEA---FAGEDCSLGRCLNDCSDQGACVNGSCQCRSGFL--GEDCSLIF--------CANNCSQR 299
Cdd:NF041328   14 CPEPGaVCPEGLSVCGGAcvdLRSDPSNCGACGVACGAGQTCVAGACGCGPGTVacGGACVDTAsdpahcgaCGAACAPG 93

                          90       100
                  ....*....|....*....|...
gi 528471437  300 GVCKEGFC--VCQEGYT--GDDC 318
Cdd:NF041328   94 QVCEGGACreACSEGLTrcGGAC 116
EGF_Tenascin super family cl46594
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 199-226 5.84e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


The actual alignment was detected with superfamily member pfam18720:

Pssm-ID: 480934  Cd Length: 29  Bit Score: 44.21  E-value: 5.84e-06
                           10        20
                   ....*....|....*....|....*...
gi 528471437   199 CPDDCSGQGICIEGDCVCDRNFGGENCS 226
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
 
Name Accession Description Interval E-value
FReD cd00087
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ...
 1037-1247 1.43e-117

Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.


Pssm-ID: 238040 [Multi-domain]  Cd Length: 215  Bit Score: 364.25  E-value: 1.43e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437 1037 PTPQNCAQHLLNGETLGGIYTIYVNRDlSQGVQVYCDMTTDGGGWIVFQRRQNGLTDFSRKWTDYKIGFGNLEDEFWLGL 1116
Cdd:cd00087     1 PLPRDCSEVLQRGGRTSGVYTIQPPGS-NEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437 1117 DNIHKIAAQGRYELRIDMKDG-QESVYANYDRFSIGDSKSLYKLRIGEYNGTAGDSLSYHQSRPFSTKDKDNDIAVTNCA 1195
Cdd:cd00087    80 EKIHLLTSQGPYELRIDLEDWeGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 528471437 1196 LSYKGAWWYKNCHRANLNGKYGESRH----SQGINWYHWKGHEFSIPFVEMKMRPF 1247
Cdd:cd00087   160 ESYSGGWWYNSCHASNLNGRYYSGGHrneyDNGINWATWKGSTYSLKFTEMKIRPK 215
FBG smart00186
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ...
 1038-1247 1.51e-112

Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.


Pssm-ID: 214548 [Multi-domain]  Cd Length: 212  Bit Score: 350.81  E-value: 1.51e-112
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   1038 TPQNCAQHLLNGETLGGIYTIYVNrDLSQGVQVYCDMTTDGGGWIVFQRRQNGLTDFSRKWTDYKIGFGNLEDEFWLGLD 1117
Cdd:smart00186    1 LPRDCSDVLQNGGKTSGLYTIYPD-GSSRPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   1118 NIHKIAAQGRYELRIDMKD-GQESVYANYDRFSIGDSKSLYKLRIGEYNGTAGD-SLSYHQSRPFSTKDKDNDIAVTNCA 1195
Cdd:smart00186   80 NIHLLTSQGKYELRIDLEDwEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159

                           170       180       190       200       210
                    ....*....|....*....|....*....|....*....|....*....|...
gi 528471437   1196 LSYKGAWWYKNCHRANLNGKYG-ESRHSQGINWYHWKGHEFSIPFVEMKMRPF 1247
Cdd:smart00186  160 EEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRPL 212
Fibrinogen_C pfam00147
Fibrinogen beta and gamma chains, C-terminal globular domain;
1038-1246 1.22e-93

Fibrinogen beta and gamma chains, C-terminal globular domain;


Pssm-ID: 395095 [Multi-domain]  Cd Length: 221  Bit Score: 299.82  E-value: 1.22e-93
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  1038 TPQNCAQHLLNGETLGGIYTIYVNRDLSQgVQVYCDMTTDGGGWIVFQRRQNGLTDFSRKWTDYKIGFGNLE-DEFWLGL 1116
Cdd:pfam00147    1 FGRDCSDVYNKGAKTSGLYTIRPDGATKP-FEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLSpGEFWLGN 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  1117 DNIHKIAAQGRYELRIDMKDGQ-ESVYANYDRFSIGDSKSLYKLRIGEYNGTAGD-------SLSYHQSRPFSTKDKDND 1188
Cdd:pfam00147   80 DKIHLLTKQGPYVLRIDLEDWNgETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDND 159

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528471437  1189 IAVTNCALSYKGAWWYKNCHRANLNGKY--GESRHSQ-GINWYHWKGHEFSIPFVEMKMRP 1246
Cdd:pfam00147  160 SPDGNCALSYGGGWWYNNCHAANLNGVYyyGGTYSKQnGIIWATWKGRWYSMKKAEMKIRP 220
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
506-941 1.28e-21

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 100.85  E-value: 1.28e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  506 IVRDISDTVAFVEWSPPKAKVDQIILRYGLVGVEGPKTTFRLQPTLSQYSLQVLRPGSTYEVSVSGVRNGTES----GVI 581
Cdd:COG3401   146 GLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESapsnEVS 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  582 STEFTTEIDAPKNLRVLSKTSISLELEWD-NSEADVEGYSVVYSTLAGDQYDKVivprNDGPSTKTTLNELMPGTEYGIG 660
Cdd:COG3401   226 VTTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKV----ATVTTTSYTDTGLTNGTTYYYR 301

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  661 ISAVLGAN----QSTPATMNARTGL-DVPLDLTVTASTDNTITLLWGTVQGP-IDHYRVTY-TSSSGVTTELTVPKDVTT 733
Cdd:COG3401   302 VTAVDAAGnesaPSNVVSVTTDLTPpAAPSGLTATAVGSSSITLSWTASSDAdVTGYNVYRsTSGGGTYTKIAETVTTTS 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  734 TTLTSLEPGTKYTITVAA--QRGRQQSTAATIDAFTGMDPPRDITVLYVTEesVTITWIQPLALFDYYRMSY-QSSKGRM 810
Cdd:COG3401   382 YTDTGLTPGTTYYYKVTAvdAAGNESAPSEEVSATTASAASGESLTASVDA--VPLTDVAGATAAASAASNPgVSAAVLA 459

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  811 DSVVIDNDINNYTLTSLHPATEYEIKLNAVRGSQESKVITTTVFTAMDMPAELTALNVTPQGALLRWNPPASSVDNYVLT 890
Cdd:COG3401   460 DGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGSLVGGSGASSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVG 539

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 528471437  891 VTRNQVTADTFLVEGNKQEYQLSQLIPSTTYSVALYATKGPLTSGTVISNF 941
Cdd:COG3401   540 ASTGDVLITDLVSLTTSASSSVSGAGLGSGNLYLITTLGGSLLTTTSTNTN 590
fn3 pfam00041
Fibronectin type III domain;
682-754 3.44e-15

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 72.06  E-value: 3.44e-15
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528471437   682 DVPLDLTVTASTDNTITLLW---GTVQGPIDHYRVTY--TSSSGVTTELTVPKDVTTTTLTSLEPGTKYTITVAAQRG 754
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYrpKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
fn3 pfam00041
Fibronectin type III domain;
323-401 1.12e-14

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 70.52  E-value: 1.12e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   323 PPMNLRVRGVSENTIDLQWEGP----AILTDYLITYAPTTPGGVQLEMRVPGNVTNITIKGLNPGLEYNVNVYAVIDNII 398
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPPpdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 528471437   399 SSP 401
Cdd:pfam00041   82 GPP 84
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 684-758 4.21e-13

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 65.71  E-value: 4.21e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437    684 PLDLTVTASTDNTITLLW-----GTVQGPIDHYRVTYTSSSGVTTELTVPKDVTTTTLTSLEPGTKYTITVAAQRGRQQS 758
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSWepppdDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 323-401 9.92e-13

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 65.21  E-value: 9.92e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  323 PPMNLRVRGVSENTIDLQWEGP----AILTDYLITYAPTTPGGVQLEMRVPGNVTNITIKGLNPGLEYNVNVYAVIDNII 398
Cdd:cd00063     3 PPTNLRVTDVTSTSVTLSWTPPeddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE 82


                  ...
gi 528471437  399 SSP 401
Cdd:cd00063    83 SPP 85
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 682-767 1.57e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.44  E-value: 1.57e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  682 DVPLDLTVTASTDNTITLLW---GTVQGPIDHYRVTY--TSSSGVTTELTVPKDVTTTTLTSLEPGTKYTITVAAQRGRQ 756
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWtppEDDGGPITGYVVEYreKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81

                          90
                  ....*....|.
gi 528471437  757 QSTAATIDAFT 767
Cdd:cd00063    82 ESPPSESVTVT 92
fn3 pfam00041
Fibronectin type III domain;
946-1018 7.55e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 59.35  E-value: 7.55e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528471437   946 DAPQNLTASEINHRSALISWQPP---IADIDNYMLTYKAADGSR--KELILDAEDTWIRLEGLAETTEYTVRLQAARG 1018
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 946-1031 2.35e-10

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 58.28  E-value: 2.35e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  946 DAPQNLTASEINHRSALISWQPPIAD---IDNYMLTYKAADGSRKELI--LDAEDTWIRLEGLAETTEYTVRLQAARGLE 1020
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81

                          90
                  ....*....|..
gi 528471437 1021 TSA-IVSTSFTT 1031
Cdd:cd00063    82 ESPpSESVTVTT 93
fn3 pfam00041
Fibronectin type III domain;
411-490 3.49e-10

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 57.81  E-value: 3.49e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   411 SNPDGLLFKSIMETSVEVQWQPLDYL---FDGWEISFIPKD-NDGGMTAQLPSTITSFHQTGLKPGEEYTVNLVALKDQG 486
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPDGngpITGYEVEYRPKNsGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....
gi 528471437   487 RSLP 490
Cdd:pfam00041   81 EGPP 84
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 946-1015 4.79e-10

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 57.24  E-value: 4.79e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 528471437    946 DAPQNLTASEINHRSALISWQPPIAD-----IDNYMLTYKAADGSRKELILDAEDTWIRLEGLAETTEYTVRLQA 1015
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRA 76
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 323-393 1.23e-09

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 56.08  E-value: 1.23e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 528471437    323 PPMNLRVRGVSENTIDLQWEGPA--ILTDYLITY--APTTPGGVQLEMRVPGNVTNITIKGLNPGLEYNVNVYAV 393
Cdd:smart00060    3 PPSNLRVTDVTSTSVTLSWEPPPddGITGYIVGYrvEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 411-497 3.71e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 55.20  E-value: 3.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  411 SNPDGLLFKSIMETSVEVQWQPLDYL---FDGWEISFIPKDNDGGMTAQL-PSTITSFHQTGLKPGEEYTVNLVALKDQG 486
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVtPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81

                          90
                  ....*....|.
gi 528471437  487 RSLPVTATVTT 497
Cdd:cd00063    82 ESPPSESVTVT 92
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 230-257 1.07e-07

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 48.83  E-value: 1.07e-07
                           10        20
                   ....*....|....*....|....*...
gi 528471437   230 CPSDCSDRGLCIDGECVCEEAFAGEDCS 257
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
GGGWT_bact NF040941
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ...
 1041-1081 1.56e-07

fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.


Pssm-ID: 468872 [Multi-domain]  Cd Length: 46  Bit Score: 48.71  E-value: 1.56e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 528471437 1041 NCAQHLLNGETLG-GIYTIYVNRD-LSQGVQVYCDMTTDGGGW 1081
Cdd:NF040941    1 SCWEILQAGPSAPsGVYWIDPDGMgGLAPFQVYCDMTTDGGGW 43
C_rich_MXAN6577 NF041328
MXAN_6577-like cysteine-rich domain;
234-318 6.68e-07

MXAN_6577-like cysteine-rich domain;


Pssm-ID: 469225 [Multi-domain]  Cd Length: 145  Bit Score: 50.14  E-value: 6.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  234 CSDRG-LCIDGECVCEEA---FAGEDCSLGRCLNDCSDQGACVNGSCQCRSGFL--GEDCSLIF--------CANNCSQR 299
Cdd:NF041328   14 CPEPGaVCPEGLSVCGGAcvdLRSDPSNCGACGVACGAGQTCVAGACGCGPGTVacGGACVDTAsdpahcgaCGAACAPG 93

                          90       100
                  ....*....|....*....|...
gi 528471437  300 GVCKEGFC--VCQEGYT--GDDC 318
Cdd:NF041328   94 QVCEGGACreACSEGLTrcGGAC 116
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 411-488 6.87e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 48.38  E-value: 6.87e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437    411 SNPDGLLFKSIMETSVEVQWQ-PLDYLFDGWEISFIPKDNDGGM---TAQLPSTITSFHQTGLKPGEEYTVNLVALKDQG 486
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEpPPDDGITGYIVGYRVEYREEGSewkEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 528471437    487 RS 488
Cdd:smart00060   82 EG 83
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 199-226 5.84e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 44.21  E-value: 5.84e-06
                           10        20
                   ....*....|....*....|....*...
gi 528471437   199 CPDDCSGQGICIEGDCVCDRNFGGENCS 226
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
319-497 9.59e-06

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 50.00  E-value: 9.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  319 TSVLPPMNLRVRGVSENTIDLQWEGPAI--LTDYLITYAPTTPGgvQLEMRVPGNVTNITIKGLNPGLEYNVNVYAV-ID 395
Cdd:COG3401   231 TPPSAPTGLTATADTPGSVTLSWDPVTEsdATGYRVYRSNSGDG--PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVdAA 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  396 NIISSPMNTL-VSTYLSNPD---GLLFKSIMETSVEVQWQP-LDYLFDGWEISfipKDNDGGMTAQL---PSTITSFHQT 467
Cdd:COG3401   309 GNESAPSNVVsVTTDLTPPAapsGLTATAVGSSSITLSWTAsSDADVTGYNVY---RSTSGGGTYTKiaeTVTTTSYTDT 385

                         170       180       190
                  ....*....|....*....|....*....|
gi 528471437  468 GLKPGEEYTVNLVALKDQGRSLPVTATVTT 497
Cdd:COG3401   386 GLTPGTTYYYKVTAVDAAGNESAPSEEVSA 415
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 291-319 9.73e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 43.44  E-value: 9.73e-06
                           10        20
                   ....*....|....*....|....*....
gi 528471437   291 FCANNCSQRGVCKEGFCVCQEGYTGDDCT 319
Cdd:pfam18720    1 YCPLGCSSRGVCVDGQCICDSEYSGDDCS 29
C_rich_MXAN6577 NF041328
MXAN_6577-like cysteine-rich domain;
199-312 2.25e-04

MXAN_6577-like cysteine-rich domain;


Pssm-ID: 469225 [Multi-domain]  Cd Length: 145  Bit Score: 42.82  E-value: 2.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  199 CPDDCSgqgICIEGDCVCdrnfGGE---------NCSEprCPSDCSDRGLCIDGECVCEEAFA--GEDC--------SLG 259
Cdd:NF041328   14 CPEPGA---VCPEGLSVC----GGAcvdlrsdpsNCGA--CGVACGAGQTCVAGACGCGPGTVacGGACvdtasdpaHCG 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 528471437  260 RCLNDCSDQGACVNGSCQ--CRSGFL--GEDC-SLIFCANNCSQRGVCKEGFCVCQEG 312
Cdd:NF041328   85 ACGAACAPGQVCEGGACReaCSEGLTrcGGACvDLATDPLHCGACGVACDPGESCRGG 142
 
Name Accession Description Interval E-value
FReD cd00087
Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is ...
 1037-1247 1.43e-117

Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular arrangement called the disulfide knot. The C termini of fibrinogen chains end in globular domains, which are not completely equivalent. C terminal globular domains of the gamma chains (C-gamma) dimerize and bind to the GPR motif of the N-terminal domain of the alpha chain, while the GHR motif of N-terminal domain of the beta chain binds to the C terminal globular domains of another beta chain (C-beta), which leads to lattice formation.


Pssm-ID: 238040 [Multi-domain]  Cd Length: 215  Bit Score: 364.25  E-value: 1.43e-117
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437 1037 PTPQNCAQHLLNGETLGGIYTIYVNRDlSQGVQVYCDMTTDGGGWIVFQRRQNGLTDFSRKWTDYKIGFGNLEDEFWLGL 1116
Cdd:cd00087     1 PLPRDCSEVLQRGGRTSGVYTIQPPGS-NEPFQVYCDMDTDGGGWTVIQRRGDGSVDFYRSWKEYKDGFGNLDGEFWLGL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437 1117 DNIHKIAAQGRYELRIDMKDG-QESVYANYDRFSIGDSKSLYKLRIGEYNGTAGDSLSYHQSRPFSTKDKDNDIAVTNCA 1195
Cdd:cd00087    80 EKIHLLTSQGPYELRIDLEDWeGNTAYAEYDSFKVGSESEGYRLTLGGYSGTAGDALSYHNGMKFSTFDRDNDGASGNCA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 528471437 1196 LSYKGAWWYKNCHRANLNGKYGESRH----SQGINWYHWKGHEFSIPFVEMKMRPF 1247
Cdd:cd00087   160 ESYSGGWWYNSCHASNLNGRYYSGGHrneyDNGINWATWKGSTYSLKFTEMKIRPK 215
FBG smart00186
Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and ...
 1038-1247 1.51e-112

Fibrinogen-related domains (FReDs); Domain present at the C-termini of fibrinogen beta and gamma chains, and a variety of fibrinogen-related proteins, including tenascin and Drosophila scabrous.


Pssm-ID: 214548 [Multi-domain]  Cd Length: 212  Bit Score: 350.81  E-value: 1.51e-112
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   1038 TPQNCAQHLLNGETLGGIYTIYVNrDLSQGVQVYCDMTTDGGGWIVFQRRQNGLTDFSRKWTDYKIGFGNLEDEFWLGLD 1117
Cdd:smart00186    1 LPRDCSDVLQNGGKTSGLYTIYPD-GSSRPLKVYCDMETDGGGWTVIQRRMDGSVDFYRDWKDYKEGFGNLAGEFWLGNE 79

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   1118 NIHKIAAQGRYELRIDMKD-GQESVYANYDRFSIGDSKSLYKLRIGEYNGTAGD-SLSYHQSRPFSTKDKDNDIAVTNCA 1195
Cdd:smart00186   80 NIHLLTSQGKYELRIDLEDwEGNTAYALYDSFKVADEADGYRLHIGGYSGTAGDaSLTYHNGMQFSTYDRDNDKYSGNCA 159

                           170       180       190       200       210
                    ....*....|....*....|....*....|....*....|....*....|...
gi 528471437   1196 LSYKGAWWYKNCHRANLNGKYG-ESRHSQGINWYHWKGHEFSIPFVEMKMRPF 1247
Cdd:smart00186  160 EEYGGGWWYNNCHAANLNGRYYpNNNYDNGINWATWKGSWYSLKFTEMKIRPL 212
Fibrinogen_C pfam00147
Fibrinogen beta and gamma chains, C-terminal globular domain;
1038-1246 1.22e-93

Fibrinogen beta and gamma chains, C-terminal globular domain;


Pssm-ID: 395095 [Multi-domain]  Cd Length: 221  Bit Score: 299.82  E-value: 1.22e-93
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  1038 TPQNCAQHLLNGETLGGIYTIYVNRDLSQgVQVYCDMTTDGGGWIVFQRRQNGLTDFSRKWTDYKIGFGNLE-DEFWLGL 1116
Cdd:pfam00147    1 FGRDCSDVYNKGAKTSGLYTIRPDGATKP-FEVYCDMETDGGGWTVFQRRLDGSTNFKRNWKDYKAGFGNLSpGEFWLGN 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  1117 DNIHKIAAQGRYELRIDMKDGQ-ESVYANYDRFSIGDSKSLYKLRIGEYNGTAGD-------SLSYHQSRPFSTKDKDND 1188
Cdd:pfam00147   80 DKIHLLTKQGPYVLRIDLEDWNgETVFALYDSFKVTNENDKYRLHVENYIGDAGDaldtagrSMTYHNGMQFSTWDRDND 159

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528471437  1189 IAVTNCALSYKGAWWYKNCHRANLNGKY--GESRHSQ-GINWYHWKGHEFSIPFVEMKMRP 1246
Cdd:pfam00147  160 SPDGNCALSYGGGWWYNNCHAANLNGVYyyGGTYSKQnGIIWATWKGRWYSMKKAEMKIRP 220
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
506-941 1.28e-21

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 100.85  E-value: 1.28e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  506 IVRDISDTVAFVEWSPPKAKVDQIILRYGLVGVEGPKTTFRLQPTLSQYSLQVLRPGSTYEVSVSGVRNGTES----GVI 581
Cdd:COG3401   146 GLYGVDGANASGTTASSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESapsnEVS 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  582 STEFTTEIDAPKNLRVLSKTSISLELEWD-NSEADVEGYSVVYSTLAGDQYDKVivprNDGPSTKTTLNELMPGTEYGIG 660
Cdd:COG3401   226 VTTPTTPPSAPTGLTATADTPGSVTLSWDpVTESDATGYRVYRSNSGDGPFTKV----ATVTTTSYTDTGLTNGTTYYYR 301

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  661 ISAVLGAN----QSTPATMNARTGL-DVPLDLTVTASTDNTITLLWGTVQGP-IDHYRVTY-TSSSGVTTELTVPKDVTT 733
Cdd:COG3401   302 VTAVDAAGnesaPSNVVSVTTDLTPpAAPSGLTATAVGSSSITLSWTASSDAdVTGYNVYRsTSGGGTYTKIAETVTTTS 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  734 TTLTSLEPGTKYTITVAA--QRGRQQSTAATIDAFTGMDPPRDITVLYVTEesVTITWIQPLALFDYYRMSY-QSSKGRM 810
Cdd:COG3401   382 YTDTGLTPGTTYYYKVTAvdAAGNESAPSEEVSATTASAASGESLTASVDA--VPLTDVAGATAAASAASNPgVSAAVLA 459

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  811 DSVVIDNDINNYTLTSLHPATEYEIKLNAVRGSQESKVITTTVFTAMDMPAELTALNVTPQGALLRWNPPASSVDNYVLT 890
Cdd:COG3401   460 DGGDTGNAVPFTTTSSTVTATTTDTTTANLSVTTGSLVGGSGASSVTNSVSVIGASAAAAVGGAPDGTPNVTGASPVTVG 539

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|.
gi 528471437  891 VTRNQVTADTFLVEGNKQEYQLSQLIPSTTYSVALYATKGPLTSGTVISNF 941
Cdd:COG3401   540 ASTGDVLITDLVSLTTSASSSVSGAGLGSGNLYLITTLGGSLLTTTSTNTN 590
fn3 pfam00041
Fibronectin type III domain;
682-754 3.44e-15

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 72.06  E-value: 3.44e-15
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528471437   682 DVPLDLTVTASTDNTITLLW---GTVQGPIDHYRVTY--TSSSGVTTELTVPKDVTTTTLTSLEPGTKYTITVAAQRG 754
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYrpKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
fn3 pfam00041
Fibronectin type III domain;
323-401 1.12e-14

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 70.52  E-value: 1.12e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   323 PPMNLRVRGVSENTIDLQWEGP----AILTDYLITYAPTTPGGVQLEMRVPGNVTNITIKGLNPGLEYNVNVYAVIDNII 398
Cdd:pfam00041    2 APSNLTVTDVTSTSLTVSWTPPpdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGE 81


                   ...
gi 528471437   399 SSP 401
Cdd:pfam00041   82 GPP 84
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 684-758 4.21e-13

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 65.71  E-value: 4.21e-13
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437    684 PLDLTVTASTDNTITLLW-----GTVQGPIDHYRVTYTSSSGVTTELTVPKDVTTTTLTSLEPGTKYTITVAAQRGRQQS 758
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSWepppdDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 323-401 9.92e-13

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 65.21  E-value: 9.92e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  323 PPMNLRVRGVSENTIDLQWEGP----AILTDYLITYAPTTPGGVQLEMRVPGNVTNITIKGLNPGLEYNVNVYAVIDNII 398
Cdd:cd00063     3 PPTNLRVTDVTSTSVTLSWTPPeddgGPITGYVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGE 82


                  ...
gi 528471437  399 SSP 401
Cdd:cd00063    83 SPP 85
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 682-767 1.57e-12

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 64.44  E-value: 1.57e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  682 DVPLDLTVTASTDNTITLLW---GTVQGPIDHYRVTY--TSSSGVTTELTVPKDVTTTTLTSLEPGTKYTITVAAQRGRQ 756
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWtppEDDGGPITGYVVEYreKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81

                          90
                  ....*....|.
gi 528471437  757 QSTAATIDAFT 767
Cdd:cd00063    82 ESPPSESVTVT 92
fn3 pfam00041
Fibronectin type III domain;
770-842 2.53e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 60.89  E-value: 2.53e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528471437   770 DPPRDITVLYVTEESVTITWIQPLAL---FDYYRMSYQS--SKGRMDSVVIDNDINNYTLTSLHPATEYEIKLNAVRG 842
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPDGngpITGYEVEYRPknSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
620-1028 5.80e-11

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 66.95  E-value: 5.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  620 SVVYSTLAGDQYDKVIVPRNDGPSTKTTLNELMPGTEYGIGISAVLGANQSTPATMNARTGLDVPLDLTVTASTDNTITL 699
Cdd:COG3401     9 LDAGIAASAAANTAVNALSKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAP 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  700 LWGTVQGPidhyrVTYTSSSGVTTELTVPKDVTTTTLTSLEPGTKYTITVAAQRG-RQQSTAATIDAFTGMDPPRDITVL 778
Cdd:COG3401    89 PTATGLTT-----LTGSGSVGGATNTGLTSSDEVPSPAVGTATTATAVAGGAATAgTYALGAGLYGVDGANASGTTASSV 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  779 YVTEESVTITWIQPLALFDYYRMSYQSSKGRMDSVVIDNDINNYTLTSLhpateyeiklNAVRGSQESKVITTTVFTAM- 857
Cdd:COG3401   164 AGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAAT----------DTGGESAPSNEVSVTTPTTPp 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  858 DMPAELTALNVTPQGALLRWNP-PASSVDNYvlTVTRNQVTADTF--LVEGNKQEYQLSQLIPSTTYSVALYA-----TK 929
Cdd:COG3401   234 SAPTGLTATADTPGSVTLSWDPvTESDATGY--RVYRSNSGDGPFtkVATVTTTSYTDTGLTNGTTYYYRVTAvdaagNE 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  930 GPLTSGTVISNFVTPMDAPQNLTASEINHRSALISWQP-PIADIDNYMLTYKAADGSRKELILD-AEDTWIRLEGLAETT 1007
Cdd:COG3401   312 SAPSNVVSVTTDLTPPAAPSGLTATAVGSSSITLSWTAsSDADVTGYNVYRSTSGGGTYTKIAEtVTTTSYTDTGLTPGT 391

                         410       420
                  ....*....|....*....|....*
gi 528471437 1008 EYTVRLQA--ARGLET--SAIVSTS 1028
Cdd:COG3401   392 TYYYKVTAvdAAGNESapSEEVSAT 416
fn3 pfam00041
Fibronectin type III domain;
946-1018 7.55e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 59.35  E-value: 7.55e-11
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528471437   946 DAPQNLTASEINHRSALISWQPP---IADIDNYMLTYKAADGSR--KELILDAEDTWIRLEGLAETTEYTVRLQAARG 1018
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKNSGEpwNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 946-1031 2.35e-10

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 58.28  E-value: 2.35e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  946 DAPQNLTASEINHRSALISWQPPIAD---IDNYMLTYKAADGSRKELI--LDAEDTWIRLEGLAETTEYTVRLQAARGLE 1020
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81

                          90
                  ....*....|..
gi 528471437 1021 TSA-IVSTSFTT 1031
Cdd:cd00063    82 ESPpSESVTVTT 93
fn3 pfam00041
Fibronectin type III domain;
411-490 3.49e-10

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 57.81  E-value: 3.49e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   411 SNPDGLLFKSIMETSVEVQWQPLDYL---FDGWEISFIPKD-NDGGMTAQLPSTITSFHQTGLKPGEEYTVNLVALKDQG 486
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPDGngpITGYEVEYRPKNsGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGG 80


                   ....
gi 528471437   487 RSLP 490
Cdd:pfam00041   81 EGPP 84
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 770-846 3.68e-10

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 57.62  E-value: 3.68e-10
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437    770 DPPRDITVLYVTEESVTITWIQP-----LALFDYYRMSYQSSKGRMDSVVIDNDINNYTLTSLHPATEYEIKLNAVRGSQ 844
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPpddgiTGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 528471437    845 ES 846
Cdd:smart00060   82 EG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 946-1015 4.79e-10

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 57.24  E-value: 4.79e-10
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 528471437    946 DAPQNLTASEINHRSALISWQPPIAD-----IDNYMLTYKAADGSRKELILDAEDTWIRLEGLAETTEYTVRLQA 1015
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRA 76
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 770-855 1.15e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 56.35  E-value: 1.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  770 DPPRDITVLYVTEESVTITWIQPL---ALFDYYRMSYQ--SSKGRMDSVVIDNDINNYTLTSLHPATEYEIKLNAVRGSQ 844
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYRekGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81

                          90
                  ....*....|.
gi 528471437  845 ESKVITTTVFT 855
Cdd:cd00063    82 ESPPSESVTVT 92
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 323-393 1.23e-09

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 56.08  E-value: 1.23e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 528471437    323 PPMNLRVRGVSENTIDLQWEGPA--ILTDYLITY--APTTPGGVQLEMRVPGNVTNITIKGLNPGLEYNVNVYAV 393
Cdd:smart00060    3 PPSNLRVTDVTSTSVTLSWEPPPddGITGYIVGYrvEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 411-497 3.71e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 55.20  E-value: 3.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  411 SNPDGLLFKSIMETSVEVQWQPLDYL---FDGWEISFIPKDNDGGMTAQL-PSTITSFHQTGLKPGEEYTVNLVALKDQG 486
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDWKEVEVtPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81

                          90
                  ....*....|.
gi 528471437  487 RSLPVTATVTT 497
Cdd:cd00063    82 ESPPSESVTVT 92
fn3 pfam00041
Fibronectin type III domain;
502-579 7.42e-09

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 53.96  E-value: 7.42e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   502 PIQLIVRDISDTVAFVEWSPPK---AKVDQIILRYGLVGVEGPKTTFRLQPTLSQYSLQVLRPGSTYEVSVSGVRNGTES 578
Cdd:pfam00041    3 PSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYRPKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEG 82


                   .
gi 528471437   579 G 579
Cdd:pfam00041   83 P 83
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 590-674 7.79e-09

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 54.04  E-value: 7.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  590 DAPKNLRVLSKTSISLELEWDNSEAD---VEGYSVVYSTLAGDQYdkVIVPRNDGPSTKTTLNELMPGTEYGIGISAVLG 666
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEDDggpITGYVVEYREKGSGDW--KEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNG 79


                  ....*...
gi 528471437  667 ANQSTPAT 674
Cdd:cd00063    80 GGESPPSE 87
fn3 pfam00041
Fibronectin type III domain;
590-672 2.07e-08

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 52.80  E-value: 2.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437   590 DAPKNLRVLSKTSISLELEW---DNSEADVEGYSVVYSTLAGDQYDKVIvpRNDGPSTKTTLNELMPGTEYGIGISAVLG 666
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWtppPDGNGPITGYEVEYRPKNSGEPWNEI--TVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78


                   ....*.
gi 528471437   667 ANQSTP 672
Cdd:pfam00041   79 GGEGPP 84
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
331-757 1.00e-07

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 56.49  E-value: 1.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  331 GVSENTIDLQWEGPAILTDYLITYAPTTpGGVQLEMRVPGnvTNITIKGLNPGlEYNVNVYAVIDNIISSPMNTLVSTYL 410
Cdd:COG4733   548 GTAVTTLTVSWDAPAGAVAYEVEWRRDD-GNWVSVPRTSG--TSFEVPGIYAG-DYEVRVRAINALGVSSAWAASSETTV 623

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  411 S-------NPDGLLFKSIMEtSVEVQWQPLDYL-FDGWEISFIPKDNDGGMT-AQLPSTITSFHQTGLKPGEEYTVNLVA 481
Cdd:COG4733   624 TgktapppAPTGLTATGGLG-GITLSWSFPVDAdTLRTEIRYSTTGDWASATvAQALYPGNTYTLAGLKAGQTYYYRARA 702

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  482 LKDQGRS--LPVTATVTTLIDGPIQLIVRDISDTVAFVEwsppkakVDQIILRYGLVGVEGPKTTFRLQPTLSQYSLQVL 559
Cdd:COG4733   703 VDRSGNVsaWWVSGQASADAAGILDAITGQILETELGQE-------LDAIIQNATVAEVVAATVTDVTAQIDTAVLFAGV 775

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  560 RPGSTYEVSVSGVRNGTESG---VISTEFTTEIDAPKNLRVLSKTSISLELEWDNS-----EADVEGYSVVYSTLAGDQY 631
Cdd:COG4733   776 ATAAAIGAEARVAATVAESAtaaAATGTAADAAGDASGGVTAGTSGTTGAGDTAASttrvaAAVVLAGVVVYGDAIIESG 855

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  632 DKVIVPRND-GPSTKTTLNELMPGTEYGIGISAVLGANQSTPATMNARTGLDVPLDLTVTASTDNTITLLWGTVQGpidh 710
Cdd:COG4733   856 NTGDIVATGdIASAAAGAVATTVSGTTAADVSAVADSTAASLTAIVIAATTIIDAIGDGTTREPAGDIGASGGAQG---- 931

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*..
gi 528471437  711 YRVTYTSSSGVTTELTVPKDVTTTTLTSLEPGTKYTITVAAQRGRQQ 757
Cdd:COG4733   932 FAVTIVGSFDGAGAVATVDAGQSVVDGVGTAVEAANGTETAAGGGSQ 978
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 230-257 1.07e-07

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 48.83  E-value: 1.07e-07
                           10        20
                   ....*....|....*....|....*...
gi 528471437   230 CPSDCSDRGLCIDGECVCEEAFAGEDCS 257
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 590-670 1.09e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 50.69  E-value: 1.09e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437    590 DAPKNLRVLSKTSISLELEWDNSEAD-VEGYSVVYSTLAGDQYDKVIVPRNDGPSTKTTLNELMPGTEYGIGISAVLGAN 668
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDgITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 528471437    669 QS 670
Cdd:smart00060   82 EG 83
GGGWT_bact NF040941
fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, ...
 1041-1081 1.56e-07

fibrinogen-like bacterial YCDxxxxGGGW domain; Pfam model PF00147, about 220 amino acids long, describes a conserved domain found in eukaryotic proteins such as fibrinogen beta and gamma chains, fincolin, and angiopoietin. This model describes a small homology domain, about 46 amino acids long, found in the PF00147 homology region of those proteins but also as a much shorter homology domain in bacterial proteins that may lack homology to those proteins, or to each other, outside this region. The signature motif, at the C-terminus of this domain, is YCDxTTDGGGWxLV.


Pssm-ID: 468872 [Multi-domain]  Cd Length: 46  Bit Score: 48.71  E-value: 1.56e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 528471437 1041 NCAQHLLNGETLG-GIYTIYVNRD-LSQGVQVYCDMTTDGGGW 1081
Cdd:NF040941    1 SCWEILQAGPSAPsGVYWIDPDGMgGLAPFQVYCDMTTDGGGW 43
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
329-818 1.74e-07

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 55.72  E-value: 1.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  329 VRGVSENTIDLQWEGPAILTDYLItYAPTTPGGVQLEMRVPG------NVTNITikglnpGLEYNVNVYAVIDN---IIS 399
Cdd:COG4733   455 VQSVAGRTLTVSTAYSETPEAGAV-WAFGPDELETQLFRVVSieenedGTYTIT------AVQHAPEKYAAIDAgafDDV 527

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  400 SPMNTLVSTYLSNPDGLLFKSIMETSVEVQWQPLDYlFDGWEISFipKDNDGGMTAQLPSTITSFHQTGLKPGeEYTVNL 479
Cdd:COG4733   528 PPQWPPVNVTTSESLSVVAQGTAVTTLTVSWDAPAG-AVAYEVEW--RRDDGNWVSVPRTSGTSFEVPGIYAG-DYEVRV 603

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  480 VALKDQGRSLPVTATVTTLIDG-------PIQLIVRDISDTVAFVeWSPPK-AKVDQIILRYGLVG-VEGPKTTFRLQPT 550
Cdd:COG4733   604 RAINALGVSSAWAASSETTVTGktapppaPTGLTATGGLGGITLS-WSFPVdADTLRTEIRYSTTGdWASATVAQALYPG 682

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  551 lSQYSLQVLRPGSTYEVSVSGV-RNGTESGVISTEfTTEIDAPKNLRVLS----KTSISLELEWDNSEADVEGYSVVYST 625
Cdd:COG4733   683 -NTYTLAGLKAGQTYYYRARAVdRSGNVSAWWVSG-QASADAAGILDAITgqilETELGQELDAIIQNATVAEVVAATVT 760

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  626 LAGDQYDKVIVPRNDGPSTKTtlnelmpGTEYGIGISAVLGANQSTPATMNARTGLDVPLDLTVTASTDNTITLLWGTVQ 705
Cdd:COG4733   761 DVTAQIDTAVLFAGVATAAAI-------GAEARVAATVAESATAAAATGTAADAAGDASGGVTAGTSGTTGAGDTAASTT 833

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  706 GpidhYRVTYTSSSGVTTELTVPKDVTTTTLTslePGTKYTITVAAQRGRQQSTAATIDAFTGMDPPRDITVLYVTEESV 785
Cdd:COG4733   834 R----VAAAVVLAGVVVYGDAIIESGNTGDIV---ATGDIASAAAGAVATTVSGTTAADVSAVADSTAASLTAIVIAATT 906

                         490       500       510
                  ....*....|....*....|....*....|....*
gi 528471437  786 TITWI--QPLALFDYYRMSYQSSKGRMDSVVIDND 818
Cdd:COG4733   907 IIDAIgdGTTREPAGDIGASGGAQGFAVTIVGSFD 941
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 500-587 1.75e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 50.19  E-value: 1.75e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  500 DGPIQLIVRDISDTVAFVEWSPPKAKVDQI---ILRYGLVGVEGPKTTFRLQPTLSQYSLQVLRPGSTYEVSVSGVRNGT 576
Cdd:cd00063     2 SPPTNLRVTDVTSTSVTLSWTPPEDDGGPItgyVVEYREKGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGG 81

                          90
                  ....*....|..
gi 528471437  577 ESG-VISTEFTT 587
Cdd:cd00063    82 ESPpSESVTVTT 93
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
717-1041 4.20e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 54.24  E-value: 4.20e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  717 SSSGVTTELTVPKDVTTTTLTSLEPGTKYTITVAAQRGRQQSTAATIDAFTGMDPPRDITVLYVTEESVTITWIQPLALF 796
Cdd:COG3401     1 TGSSYLTSLDAGIAASAAANTAVNALSKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  797 DYYRMSYQSSKGRMDSVVIDNDINNYTLTSLHPATEYEIKLNAVRGSQESKVITTTVFTAMDMPAELTALNVTPQGALLR 876
Cdd:COG3401    81 AVAVAAAPPTATGLTTLTGSGSVGGATNTGLTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  877 WNPPASSVDNYVLTVTRNQVTADTFLVEGNKQEYQLSQLIPSTTYSVALYAT----KGPLTSGTVISNFVTPMDAPQNLT 952
Cdd:COG3401   161 SSVAGAGVVVSPDTSATAAVATTSLTVTSTTLVDGGGDIEPGTTYYYRVAATdtggESAPSNEVSVTTPTTPPSAPTGLT 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  953 ASEINHRSALISWQP-PIADIDNYMLTYKAADGSRKELILDAEDTWIRLEGLAETTEYTVRLQA--ARGLET--SAIVST 1027
Cdd:COG3401   241 ATADTPGSVTLSWDPvTESDATGYRVYRSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAvdAAGNESapSNVVSV 320

                         330
                  ....*....|....
gi 528471437 1028 sfTTGNRLFPTPQN 1041
Cdd:COG3401   321 --TTDLTPPAAPSG 332
C_rich_MXAN6577 NF041328
MXAN_6577-like cysteine-rich domain;
234-318 6.68e-07

MXAN_6577-like cysteine-rich domain;


Pssm-ID: 469225 [Multi-domain]  Cd Length: 145  Bit Score: 50.14  E-value: 6.68e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  234 CSDRG-LCIDGECVCEEA---FAGEDCSLGRCLNDCSDQGACVNGSCQCRSGFL--GEDCSLIF--------CANNCSQR 299
Cdd:NF041328   14 CPEPGaVCPEGLSVCGGAcvdLRSDPSNCGACGVACGAGQTCVAGACGCGPGTVacGGACVDTAsdpahcgaCGAACAPG 93

                          90       100
                  ....*....|....*....|...
gi 528471437  300 GVCKEGFC--VCQEGYT--GDDC 318
Cdd:NF041328   94 QVCEGGACreACSEGLTrcGGAC 116
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 411-488 6.87e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 48.38  E-value: 6.87e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437    411 SNPDGLLFKSIMETSVEVQWQ-PLDYLFDGWEISFIPKDNDGGM---TAQLPSTITSFHQTGLKPGEEYTVNLVALKDQG 486
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEpPPDDGITGYIVGYRVEYREEGSewkEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAG 81


                    ..
gi 528471437    487 RS 488
Cdd:smart00060   82 EG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 500-578 3.73e-06

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 46.07  E-value: 3.73e-06
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437    500 DGPIQLIVRDISDTVAFVEWSPPK-AKVDQIILRYGLVGVEGPKTTFRLQPTLSQYSLQV--LRPGSTYEVSVSGVRNGT 576
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPdDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLtgLKPGTEYEFRVRAVNGAG 81


                    ..
gi 528471437    577 ES 578
Cdd:smart00060   82 EG 83
fn3 pfam00041
Fibronectin type III domain;
860-930 3.78e-06

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 46.25  E-value: 3.78e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528471437   860 PAELTALNVTPQGALLRWNPPA---SSVDNYVLTV--TRNQVTADTFLVEGNKQEYQLSQLIPSTTYSVALYATKG 930
Cdd:pfam00041    3 PSNLTVTDVTSTSLTVSWTPPPdgnGPITGYEVEYrpKNSGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNG 78
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 199-226 5.84e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 44.21  E-value: 5.84e-06
                           10        20
                   ....*....|....*....|....*...
gi 528471437   199 CPDDCSGQGICIEGDCVCDRNFGGENCS 226
Cdd:pfam18720    2 CPLGCSSRGVCVDGQCICDSEYSGDDCS 29
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
319-497 9.59e-06

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 50.00  E-value: 9.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  319 TSVLPPMNLRVRGVSENTIDLQWEGPAI--LTDYLITYAPTTPGgvQLEMRVPGNVTNITIKGLNPGLEYNVNVYAV-ID 395
Cdd:COG3401   231 TPPSAPTGLTATADTPGSVTLSWDPVTEsdATGYRVYRSNSGDG--PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVdAA 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  396 NIISSPMNTL-VSTYLSNPD---GLLFKSIMETSVEVQWQP-LDYLFDGWEISfipKDNDGGMTAQL---PSTITSFHQT 467
Cdd:COG3401   309 GNESAPSNVVsVTTDLTPPAapsGLTATAVGSSSITLSWTAsSDADVTGYNVY---RSTSGGGTYTKiaeTVTTTSYTDT 385

                         170       180       190
                  ....*....|....*....|....*....|
gi 528471437  468 GLKPGEEYTVNLVALKDQGRSLPVTATVTT 497
Cdd:COG3401   386 GLTPGTTYYYKVTAVDAAGNESAPSEEVSA 415
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 291-319 9.73e-06

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 43.44  E-value: 9.73e-06
                           10        20
                   ....*....|....*....|....*....
gi 528471437   291 FCANNCSQRGVCKEGFCVCQEGYTGDDCT 319
Cdd:pfam18720    1 YCPLGCSSRGVCVDGQCICDSEYSGDDCS 29
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 860-927 7.90e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 42.60  E-value: 7.90e-05
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 528471437    860 PAELTALNVTPQGALLRWNPPASS-----VDNYVLTVTRNQVTADTFLVEGNKQEYQLSQLIPSTTYSVALYA 927
Cdd:smart00060    4 PSNLRVTDVTSTSVTLSWEPPPDDgitgyIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRA 76
EB pfam01683
EB module; This domain has no known function. It is found in several C. elegans proteins. The ...
 234-282 8.32e-05

EB module; This domain has no known function. It is found in several C. elegans proteins. The domain contains 8 conserved cysteines that probably form four disulphide bridges. This domain is found associated with kunitz domains pfam00014.


Pssm-ID: 460294  Cd Length: 52  Bit Score: 41.26  E-value: 8.32e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 528471437   234 CSDRGLCIDGECVcEEAFAGEDCSLGRclnDCSDQGACVNGSCQCRSGF 282
Cdd:pfam01683    1 CPPGQVLVNGQCV-PKVAPGESCEADE---QCPGGSVCVNGVCQCPPGF 45
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 860-927 1.04e-04

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 42.48  E-value: 1.04e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 528471437  860 PAELTALNVTPQGALLRWNPPA---SSVDNYVLTVTRNQVTADTFL--VEGNKQEYQLSQLIPSTTYSVALYA 927
Cdd:cd00063     4 PTNLRVTDVTSTSVTLSWTPPEddgGPITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRA 76
C_rich_MXAN6577 NF041328
MXAN_6577-like cysteine-rich domain;
199-312 2.25e-04

MXAN_6577-like cysteine-rich domain;


Pssm-ID: 469225 [Multi-domain]  Cd Length: 145  Bit Score: 42.82  E-value: 2.25e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  199 CPDDCSgqgICIEGDCVCdrnfGGE---------NCSEprCPSDCSDRGLCIDGECVCEEAFA--GEDC--------SLG 259
Cdd:NF041328   14 CPEPGA---VCPEGLSVC----GGAcvdlrsdpsNCGA--CGVACGAGQTCVAGACGCGPGTVacGGACvdtasdpaHCG 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 528471437  260 RCLNDCSDQGACVNGSCQ--CRSGFL--GEDC-SLIFCANNCSQRGVCKEGFCVCQEG 312
Cdd:NF041328   85 ACGAACAPGQVCEGGACReaCSEGLTrcGGACvDLATDPLHCGACGVACDPGESCRGG 142
EGF_2 pfam07974
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
 296-318 8.90e-04

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.


Pssm-ID: 400365  Cd Length: 26  Bit Score: 37.71  E-value: 8.90e-04
                           10        20
                   ....*....|....*....|....*
gi 528471437   296 CSQRGVC--KEGFCVCQEGYTGDDC 318
Cdd:pfam07974    2 CSGRGTCvnQCGKCVCDSGYQGATC 26
EGF_Tenascin pfam18720
Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.
 256-288 2.31e-03

Tenascin EGF domain; This entry represents the EGF-like domains found in tenascin proteins.


Pssm-ID: 376143  Cd Length: 29  Bit Score: 36.89  E-value: 2.31e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 528471437   256 CSLGrclndCSDQGACVNGSCQCRSGFLGEDCS 288
Cdd:pfam18720    2 CPLG-----CSSRGVCVDGQCICDSEYSGDDCS 29
COG3979 COG3979
Chitodextrinase [Carbohydrate transport and metabolism];
591-823 4.39e-03

Chitodextrinase [Carbohydrate transport and metabolism];


Pssm-ID: 443178 [Multi-domain]  Cd Length: 369  Bit Score: 40.91  E-value: 4.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  591 APKNLRVLSKTSISLELEWDNS--EADVEGYsVVYStlAGDQydkviVPRNDGpSTKTTLNELMPGTEYGIGISAVLGA- 667
Cdd:COG3979     5 APTGLTASNVTSSSVSLSWDAStdNVGVTGY-DVYR--GGDQ-----VATVTG-LTAWTVTGLTPGTEYTFTVGACDAAg 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  668 NQSTPATMNARTGLDVPLDLTVTASTDNTITLLWGTVQGPIDHYRVTYTSSSGVTTELTVPKDVTTTTLTSLEPGTKYTI 747
Cdd:COG3979    76 NVSAASGTSTAMFGGSSTTLGSAEGVADTSGNLAASGAFFGVTTPPTPSSTLVVDGTTTVNAAATANGGTGGSGGTTTII 155

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528471437  748 TVAAQRGRQQSTAATIDAFTGmDPPRDITVLYVTEESVTITWIQPLALFDYYRMSYQSSKGRMDSVVIDNDINNYT 823
Cdd:COG3979   156 TTGVEGGGGSKTAQSLNAITA-AGTAALNGGVVGGADEVLTCSAVKDDGSGGAGAGNTYWALNTLGVSDTPSGTTA 230
COG1470 COG1470
Uncharacterized membrane protein [Function unknown];
544-957 5.71e-03

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 441079 [Multi-domain]  Cd Length: 475  Bit Score: 40.61  E-value: 5.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  544 TFRLQPTLSQYSLQVlRPGSTYEVSVSgVRN-GTESGVISteFTTEiDAPKNLRVLSKTSISLELEwDNSEADVEGY-SV 621
Cdd:COG1470    94 PYGLTLSVESPSLEV-APGETVTYTVT-LTNtGDEPDTVS--LSAE-GLPEGWTVTFTPDTSVSLA-PGESKTVTLEvTP 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  622 VYSTLAGDqYDKVIVPRNDGPSTKTTLN-ELMPGTEYGIGISavlganqSTPATMNARTGLDVPLDLTVTastdNTitll 700
Cdd:COG1470   168 PANAEPGT-YPVTVTATSGEDSSSASLTlTLTVTGSYELELS-------STPTGRTVTPGESATFTVTVT----NT---- 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  701 wGTVqGPIDHYRVTYTSSSGVTTEltvpkdVTTTTLTSLEPGTKYTITVAAQrGRQQSTAATIDA-FTGMDPPRDITVLY 779
Cdd:COG1470   232 -GNG-ADLTNVTLSASAPSGWTVS------FEPETIPSLAPGESATVTLTVT-VPADATAGDYTVtVTATSDETASATLR 302

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  780 VTEESVTItWIQPLALFDYYRMSYQSSKGRMDSVVIDNDINNYTLTSLHPATeyeiklnavrgsqeskvitttvftamDM 859
Cdd:COG1470   303 LTVETSSL-WGWIGYLIRKYGGLGATGSLLVASVSLVVGAVVGTLTTPLLLT--------------------------GF 355

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  860 PAELTALNVTPQGALLRWNPPASSVDNYVLTVTRNQVTADTFLVEGNKQEYQLSQLIPSTTYSVALYATKgPLTSGTVIS 939
Cdd:COG1470   356 AGNGLLSAATAPLLLLLGLTLSLLSDVLVFTVGSAGVSAAAATAETSALTALGVGATGAVGSGSASASVK-VTGGAAVAT 434

                         410
                  ....*....|....*...
gi 528471437  940 NFVTPMDAPQNLTASEIN 957
Cdd:COG1470   435 GLTDATTLPGAGSTATLA 452
COG3979 COG3979
Chitodextrinase [Carbohydrate transport and metabolism];
683-985 7.65e-03

Chitodextrinase [Carbohydrate transport and metabolism];


Pssm-ID: 443178 [Multi-domain]  Cd Length: 369  Bit Score: 40.14  E-value: 7.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  683 VPLDLTVTASTDNTITLLWG--TVQGPIDHYRVtYTSssgvTTELTVPKDVTTTTLTSLEPGTKYTITVAAQRGRQQSTA 760
Cdd:COG3979     5 APTGLTASNVTSSSVSLSWDasTDNVGVTGYDV-YRG----GDQVATVTGLTAWTVTGLTPGTEYTFTVGACDAAGNVSA 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  761 ATIDAFTGMDPPRDITVLYVTEESVTITWIQPLALFDYYRMSYQSSKGRMDSVVIDNDINNYTLTSLHPATEYEIKLNAV 840
Cdd:COG3979    80 ASGTSTAMFGGSSTTLGSAEGVADTSGNLAASGAFFGVTTPPTPSSTLVVDGTTTVNAAATANGGTGGSGGTTTIITTGV 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528471437  841 RGSQESKVITTTVFTAMDMPAELTALNVTPQGALLRWNPpasSVDNYVLTVTRNQVTADTFLVEGNKQEYQLSQLIPSTT 920
Cdd:COG3979   160 EGGGGSKTAQSLNAITAAGTAALNGGVVGGADEVLTCSA---VKDDGSGGAGAGNTYWALNTLGVSDTPSGTTATGGTVG 236

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 528471437  921 YSVALYATKGPLTSGTVISNFVTPMDAPQNLTASEINHRSALISWQPPIADIDNYMLTYKAADGS 985
Cdd:COG3979   237 ITSAYGAGVSGNAAVNVNAGFVVGNVGGAAGNTGTTSGTATSDAATNDVGDAAVTGLNDGAANGP 301
DUF4998 pfam16389
Domain of unknown function; This family around 200 residues locates in the N-terminal of some ...
 687-746 7.96e-03

Domain of unknown function; This family around 200 residues locates in the N-terminal of some uncharacterized proteins in various Bacteroides and Parabacteroides species. The function of this family remains unknown.


Pssm-ID: 435316 [Multi-domain]  Cd Length: 199  Bit Score: 39.22  E-value: 7.96e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528471437   687 LTVTASTDNTITLLW-GTVQGPIDHYRVTYTSSSGVTTELTVPKDVTTTTLTSLEPGTKYT 746
Cdd:pfam16389  124 KSVEITAGSNLTINWsPVLASALVGTEVTYTNNDGKVKTVRIKNGETQTVLPDFKPGTSFK 184
EGF_2 pfam07974
EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.
 202-225 8.69e-03

EGF-like domain; This family contains EGF domains found in a variety of extracellular proteins.


Pssm-ID: 400365  Cd Length: 26  Bit Score: 35.02  E-value: 8.69e-03
                           10        20
                   ....*....|....*....|....*.
gi 528471437   202 DCSGQGICI--EGDCVCDRNFGGENC 225
Cdd:pfam07974    1 ICSGRGTCVnqCGKCVCDSGYQGATC 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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