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Conserved domains on  [gi|528507009|ref|XP_005169933|]
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glycoprotein hormones alpha chain isoform X1 [Danio rerio]

Protein Classification

Hormone_6 domain-containing protein( domain architecture ID 10446400)

Hormone_6 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Hormone_6 pfam00236
Glycoprotein hormone;
24-116 9.28e-54

Glycoprotein hormone;


:

Pssm-ID: 425545  Cd Length: 95  Bit Score: 163.05  E-value: 9.28e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528507009   24 YSRNDVSNYGCEECKLKMNERFSKPGAPVYQCVGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKESKMVAT--NIPL 101
Cdd:pfam00236   1 YPDGDLSNQGCPECKLKENTYFSKPGAPIYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKASYRVTVmgNIKV 80

                          90
                  ....*....|....*
gi 528507009  102 YNHTDCHCSTCYYHK 116
Cdd:pfam00236  81 ENHTECHCSTCYYHK 95
 
Name Accession Description Interval E-value
Hormone_6 pfam00236
Glycoprotein hormone;
24-116 9.28e-54

Glycoprotein hormone;


Pssm-ID: 425545  Cd Length: 95  Bit Score: 163.05  E-value: 9.28e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528507009   24 YSRNDVSNYGCEECKLKMNERFSKPGAPVYQCVGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKESKMVAT--NIPL 101
Cdd:pfam00236   1 YPDGDLSNQGCPECKLKENTYFSKPGAPIYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKASYRVTVmgNIKV 80

                          90
                  ....*....|....*
gi 528507009  102 YNHTDCHCSTCYYHK 116
Cdd:pfam00236  81 ENHTECHCSTCYYHK 95
GHA smart00067
Glycoprotein hormone alpha chain homologues; Also called gonadotropins. Glycoprotein hormones ...
 33-117 9.29e-46

Glycoprotein hormone alpha chain homologues; Also called gonadotropins. Glycoprotein hormones consist of two glycosylated chains (alpha and beta) of similar topology.


Pssm-ID: 128381  Cd Length: 87  Bit Score: 142.65  E-value: 9.29e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528507009    33 GCEECKLKMNERFSKPGAPVYQCVGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKESKMVAT--NIPLYNHTDCHCS 110
Cdd:smart00067   1 GCPECTLKENKIFSKPGAPIYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKEFYRVTVmdNIKVENHTECHCS 80


                   ....*..
gi 528507009   111 TCYYHKS 117
Cdd:smart00067  81 TCYYHKS 87
YrdD COG0551
DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination ...
 24-60 1.40e-03

DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination and repair];


Pssm-ID: 440317 [Multi-domain]  Cd Length: 695  Bit Score: 36.77  E-value: 1.40e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 528507009  24 YSRNDVSNYGCEECKLKMNERFSKPGAPVYQCVG---CCF 60
Cdd:COG0551  621 LPKPEVTGVKCPKCGKKLVLRKSKKGKVFYGCSNypkCKF 660
 
Name Accession Description Interval E-value
Hormone_6 pfam00236
Glycoprotein hormone;
24-116 9.28e-54

Glycoprotein hormone;


Pssm-ID: 425545  Cd Length: 95  Bit Score: 163.05  E-value: 9.28e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528507009   24 YSRNDVSNYGCEECKLKMNERFSKPGAPVYQCVGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKESKMVAT--NIPL 101
Cdd:pfam00236   1 YPDGDLSNQGCPECKLKENTYFSKPGAPIYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKASYRVTVmgNIKV 80

                          90
                  ....*....|....*
gi 528507009  102 YNHTDCHCSTCYYHK 116
Cdd:pfam00236  81 ENHTECHCSTCYYHK 95
GHA smart00067
Glycoprotein hormone alpha chain homologues; Also called gonadotropins. Glycoprotein hormones ...
 33-117 9.29e-46

Glycoprotein hormone alpha chain homologues; Also called gonadotropins. Glycoprotein hormones consist of two glycosylated chains (alpha and beta) of similar topology.


Pssm-ID: 128381  Cd Length: 87  Bit Score: 142.65  E-value: 9.29e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528507009    33 GCEECKLKMNERFSKPGAPVYQCVGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKESKMVAT--NIPLYNHTDCHCS 110
Cdd:smart00067   1 GCPECTLKENKIFSKPGAPIYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKEFYRVTVmdNIKVENHTECHCS 80


                   ....*..
gi 528507009   111 TCYYHKS 117
Cdd:smart00067  81 TCYYHKS 87
YrdD COG0551
DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination ...
 24-60 1.40e-03

DNA topoisomerase I, ssDNA-binding Zn-finger and Zn-ribbon domains [Replication, recombination and repair];


Pssm-ID: 440317 [Multi-domain]  Cd Length: 695  Bit Score: 36.77  E-value: 1.40e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 528507009  24 YSRNDVSNYGCEECKLKMNERFSKPGAPVYQCVG---CCF 60
Cdd:COG0551  621 LPKPEVTGVKCPKCGKKLVLRKSKKGKVFYGCSNypkCKF 660
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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