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Conserved domains on  [gi|528487995|ref|XP_005167207|]
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sodium-dependent phosphate transporter 1-A isoform X1 [Danio rerio]

Protein Classification

inorganic phosphate transporter( domain architecture ID 10475700)

inorganic phosphate transporter is involved in phosphate transport, such as bacterial low-affinity inorganic phosphate transporter and vertebrate sodium-dependent phosphate transporters, which play fundamental housekeeping roles in phosphate transport

Gene Ontology:  GO:0005315|GO:0006817|GO:0016020
TCDB:  2.A.20

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
473-633 3.32e-73

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


:

Pssm-ID: 460184  Cd Length: 322  Bit Score: 238.55  E-value: 3.32e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  473 EIDKPEVSTLFQFLQILTACFGSFAHGGNDVSNAIGPLV-ALWLIYDSASVAPSAPTPIWLLLYGGVGICTGLWIWGRRV 551
Cdd:pfam01384 161 AKYDNKVERLFRFLQILSAALVSFAHGANDVQNAMGPLTaALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTGGWRI 240
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  552 IQTMGKDLTPITPSSGFSIELASAITVVVASNIGLPVSTTHCKVGSVVSVGWLRSRKAVDWHLFRNIFIAWFVTVPISGL 631
Cdd:pfam01384 241 IKTVGNKITKLTPSRGFAAELAAAITVLLASRLGLPVSTTHVIVGAIVGVGLARGLSAVNWGVVGNIVLAWVLTLPVAAL 320

                  ..
gi 528487995  632 IS 633
Cdd:pfam01384 321 LS 322
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
45-204 3.14e-62

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


:

Pssm-ID: 460184  Cd Length: 322  Bit Score: 209.66  E-value: 3.14e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995   45 GANDVANSFGTAVGSGVVTLRQACILATIFETVGAMLLGAKVSETIRSGIIDVHMyngSEAVLMAGSISAMFGSAVWQLA 124
Cdd:pfam01384   1 GANDVANAFATSVGSRALTPRQAVILAAIFEFLGAVLLGARVAETIGKGIVDVSF---DPGVLMLGMLAALLGAAIWLLI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  125 ASFLKLPISGTHCIVGATIGFSMVARGHQGVKWLELLRIVASWFLSPLLSGIMSAVLFYFVRKFILNKDDPVPnGLRALP 204
Cdd:pfam01384  78 ATYLGLPVSSTHALVGALIGAGLAAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLILRRKNPLK-ALRLLP 156
 
Name Accession Description Interval E-value
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
473-633 3.32e-73

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 238.55  E-value: 3.32e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  473 EIDKPEVSTLFQFLQILTACFGSFAHGGNDVSNAIGPLV-ALWLIYDSASVAPSAPTPIWLLLYGGVGICTGLWIWGRRV 551
Cdd:pfam01384 161 AKYDNKVERLFRFLQILSAALVSFAHGANDVQNAMGPLTaALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTGGWRI 240
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  552 IQTMGKDLTPITPSSGFSIELASAITVVVASNIGLPVSTTHCKVGSVVSVGWLRSRKAVDWHLFRNIFIAWFVTVPISGL 631
Cdd:pfam01384 241 IKTVGNKITKLTPSRGFAAELAAAITVLLASRLGLPVSTTHVIVGAIVGVGLARGLSAVNWGVVGNIVLAWVLTLPVAAL 320

                  ..
gi 528487995  632 IS 633
Cdd:pfam01384 321 LS 322
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
45-204 3.14e-62

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 209.66  E-value: 3.14e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995   45 GANDVANSFGTAVGSGVVTLRQACILATIFETVGAMLLGAKVSETIRSGIIDVHMyngSEAVLMAGSISAMFGSAVWQLA 124
Cdd:pfam01384   1 GANDVANAFATSVGSRALTPRQAVILAAIFEFLGAVLLGARVAETIGKGIVDVSF---DPGVLMLGMLAALLGAAIWLLI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  125 ASFLKLPISGTHCIVGATIGFSMVARGHQGVKWLELLRIVASWFLSPLLSGIMSAVLFYFVRKFILNKDDPVPnGLRALP 204
Cdd:pfam01384  78 ATYLGLPVSSTHALVGALIGAGLAAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLILRRKNPLK-ALRLLP 156
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
479-640 6.21e-47

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 168.42  E-value: 6.21e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995 479 VSTLFQFLQILTACFGSFAHGGNDVSNAIGPLVALWLiydSASVAPSAPTPIWLLLYGGVGICTGLWIWGRRVIQTMGKD 558
Cdd:COG0306  168 VNRGFRRLQIVSAALMAFSHGANDAQKAMGIITLALL---AAGLLSGFEVPLWVILLCALAIALGTLLGGWRIIKTLGKK 244
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995 559 LTPITPSSGFSIELASAITVVVASNIGLPVSTTHCKVGSVVSVGWLRSRKAVDWHLFRNIFIAWFVTVPISGLISAAIMA 638
Cdd:COG0306  245 ITKLDPLQGFAAETSSAATVLLASLLGIPVSTTHVITGSIMGVGAARRLSAVRWGVAGRIVLAWVLTLPAAALLAALLYL 324

                 ..
gi 528487995 639 LF 640
Cdd:COG0306  325 LL 326
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
26-255 7.46e-46

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 165.34  E-value: 7.46e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  26 VLWLLILGFVIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILATIFETVGAMLLGAKVSETIRSGIIDVhmyngsEA 105
Cdd:COG0306    3 TLLLLIVVILLALFFDFNNGFHDAANAIATAVGTRALSPRTAVLLAAVFNFLGALLFGTAVAKTIGKGIVDP------GI 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995 106 VLMAGSISAMFGSAVWQLAASFLKLPISGTHCIVGATIGFSMVARGHQGVKWLELLRIVASWFLSPLLSGIMSAVLFYFV 185
Cdd:COG0306   77 LTLEVVLAALLGAILWNLITWYLGIPSSSSHALVGGLVGAGLAAAGFGAVNWGVLLKIVLPWVLSPLIGFLLGFLLMRLL 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995 186 RKFILNKD-DPVPNGLRALPV----FYAVTMGIN-------LFSIMFTGAPMLGFDRIPWWGTLLISLGCAILTALVVWF 253
Cdd:COG0306  157 YWLFRRANpRRVNRGFRRLQIvsaaLMAFSHGANdaqkamgIITLALLAAGLLSGFEVPLWVILLCALAIALGTLLGGWR 236

                 ..
gi 528487995 254 IV 255
Cdd:COG0306  237 II 238
 
Name Accession Description Interval E-value
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
473-633 3.32e-73

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 238.55  E-value: 3.32e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  473 EIDKPEVSTLFQFLQILTACFGSFAHGGNDVSNAIGPLV-ALWLIYDSASVAPSAPTPIWLLLYGGVGICTGLWIWGRRV 551
Cdd:pfam01384 161 AKYDNKVERLFRFLQILSAALVSFAHGANDVQNAMGPLTaALYAIGTTGEVASKAPVPLWVLLLGALAIALGTWTGGWRI 240
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  552 IQTMGKDLTPITPSSGFSIELASAITVVVASNIGLPVSTTHCKVGSVVSVGWLRSRKAVDWHLFRNIFIAWFVTVPISGL 631
Cdd:pfam01384 241 IKTVGNKITKLTPSRGFAAELAAAITVLLASRLGLPVSTTHVIVGAIVGVGLARGLSAVNWGVVGNIVLAWVLTLPVAAL 320

                  ..
gi 528487995  632 IS 633
Cdd:pfam01384 321 LS 322
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
45-204 3.14e-62

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 209.66  E-value: 3.14e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995   45 GANDVANSFGTAVGSGVVTLRQACILATIFETVGAMLLGAKVSETIRSGIIDVHMyngSEAVLMAGSISAMFGSAVWQLA 124
Cdd:pfam01384   1 GANDVANAFATSVGSRALTPRQAVILAAIFEFLGAVLLGARVAETIGKGIVDVSF---DPGVLMLGMLAALLGAAIWLLI 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  125 ASFLKLPISGTHCIVGATIGFSMVARGHQGVKWLELLRIVASWFLSPLLSGIMSAVLFYFVRKFILNKDDPVPnGLRALP 204
Cdd:pfam01384  78 ATYLGLPVSSTHALVGALIGAGLAAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLILRRKNPLK-ALRLLP 156
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
479-640 6.21e-47

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 168.42  E-value: 6.21e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995 479 VSTLFQFLQILTACFGSFAHGGNDVSNAIGPLVALWLiydSASVAPSAPTPIWLLLYGGVGICTGLWIWGRRVIQTMGKD 558
Cdd:COG0306  168 VNRGFRRLQIVSAALMAFSHGANDAQKAMGIITLALL---AAGLLSGFEVPLWVILLCALAIALGTLLGGWRIIKTLGKK 244
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995 559 LTPITPSSGFSIELASAITVVVASNIGLPVSTTHCKVGSVVSVGWLRSRKAVDWHLFRNIFIAWFVTVPISGLISAAIMA 638
Cdd:COG0306  245 ITKLDPLQGFAAETSSAATVLLASLLGIPVSTTHVITGSIMGVGAARRLSAVRWGVAGRIVLAWVLTLPAAALLAALLYL 324

                 ..
gi 528487995 639 LF 640
Cdd:COG0306  325 LL 326
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
26-255 7.46e-46

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 165.34  E-value: 7.46e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  26 VLWLLILGFVIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILATIFETVGAMLLGAKVSETIRSGIIDVhmyngsEA 105
Cdd:COG0306    3 TLLLLIVVILLALFFDFNNGFHDAANAIATAVGTRALSPRTAVLLAAVFNFLGALLFGTAVAKTIGKGIVDP------GI 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995 106 VLMAGSISAMFGSAVWQLAASFLKLPISGTHCIVGATIGFSMVARGHQGVKWLELLRIVASWFLSPLLSGIMSAVLFYFV 185
Cdd:COG0306   77 LTLEVVLAALLGAILWNLITWYLGIPSSSSHALVGGLVGAGLAAAGFGAVNWGVLLKIVLPWVLSPLIGFLLGFLLMRLL 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995 186 RKFILNKD-DPVPNGLRALPV----FYAVTMGIN-------LFSIMFTGAPMLGFDRIPWWGTLLISLGCAILTALVVWF 253
Cdd:COG0306  157 YWLFRRANpRRVNRGFRRLQIvsaaLMAFSHGANdaqkamgIITLALLAAGLLSGFEVPLWVILLCALAIALGTLLGGWR 236

                 ..
gi 528487995 254 IV 255
Cdd:COG0306  237 II 238
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
499-645 2.33e-17

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 83.70  E-value: 2.33e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  499 GGNDVSNAIGPlvalwliydsaSVAPSAPTPIWLLLYGGVGICTGLWIWGRRVIQTMGKDLTPITPSSG------FSIEL 572
Cdd:pfam01384   1 GANDVANAFAT-----------SVGSRALTPRQAVILAAIFEFLGAVLLGARVAETIGKGIVDVSFDPGvlmlgmLAALL 69
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 528487995  573 ASAITVVVASNIGLPVSTTHCKVGSVVSVGW-LRSRKAVDWHLFRNIFIAWFVTVPISGLISAAIMALFYYVIL 645
Cdd:pfam01384  70 GAAIWLLIATYLGLPVSSTHALVGALIGAGLaAAGFDAVNWGGLGKIVASWVISPLLGGIIAALLFLLIRRLIL 143
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
28-189 2.50e-17

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 83.68  E-value: 2.50e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995  28 WLLILGFVIAFILAFSVGANDVANSFGTAVGSGVVTLRQAC--------ILATIFETVGAMLLGAKVSETIRSGIIDVHM 99
Cdd:COG0306  171 GFRRLQIVSAALMAFSHGANDAQKAMGIITLALLAAGLLSGfevplwviLLCALAIALGTLLGGWRIIKTLGKKITKLDP 250
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995 100 YNGseavlmagsISAMFGSAVWQLAASFLKLPISGTHCIVGATIGFSMvARGHQGVKWLELLRIVASWFLSPLLSGIMSA 179
Cdd:COG0306  251 LQG---------FAAETSSAATVLLASLLGIPVSTTHVITGSIMGVGA-ARRLSAVRWGVAGRIVLAWVLTLPAAALLAA 320
                        170
                 ....*....|
gi 528487995 180 VLFYFVRKFI 189
Cdd:COG0306  321 LLYLLLSLLG 330
PHO4 pfam01384
Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is ...
28-178 2.10e-16

Phosphate transporter family; This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.


Pssm-ID: 460184  Cd Length: 322  Bit Score: 80.62  E-value: 2.10e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995   28 WLLILgfvIAFILAFSVGANDVANSFG------------TAVGSGVVTLRQACILATIFETVGAMLLGAKVSETIRSGII 95
Cdd:pfam01384 173 FLQIL---SAALVSFAHGANDVQNAMGpltaalyaigttGEVASKAPVPLWVLLLGALAIALGTWTGGWRIIKTVGNKIT 249
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995   96 DVHMYNGseavlmagsISAMFGSAVWQLAASFLKLPISGTHCIVGATIGfSMVARGHQGVKWLELLRIVASWFLSPLLSG 175
Cdd:pfam01384 250 KLTPSRG---------FAAELAAAITVLLASRLGLPVSTTHVIVGAIVG-VGLARGLSAVNWGVVGNIVLAWVLTLPVAA 319

                  ...
gi 528487995  176 IMS 178
Cdd:pfam01384 320 LLS 322
PitA COG0306
Phosphate/sulfate permease [Inorganic ion transport and metabolism];
488-644 5.13e-15

Phosphate/sulfate permease [Inorganic ion transport and metabolism];


Pssm-ID: 440075  Cd Length: 330  Bit Score: 76.74  E-value: 5.13e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995 488 ILTACFGSFAHGGNDVSNAIGPlvalwliydsaSVAPSAPTPIWLLLYGGVGICTGLWIWGRRVIQTMGKDLTP---ITP 564
Cdd:COG0306   11 ILLALFFDFNNGFHDAANAIAT-----------AVGTRALSPRTAVLLAAVFNFLGALLFGTAVAKTIGKGIVDpgiLTL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528487995 565 SSGFSIELASAITVVVASNIGLPVSTTHCKVGSVVSVGW-LRSRKAVDWHLFRNIFIAWFVTVPISGLISAAIMALFYYV 643
Cdd:COG0306   80 EVVLAALLGAILWNLITWYLGIPSSSSHALVGGLVGAGLaAAGFGAVNWGVLLKIVLPWVLSPLIGFLLGFLLMRLLYWL 159

                 .
gi 528487995 644 I 644
Cdd:COG0306  160 F 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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