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Conserved domains on  [gi|528510347|ref|XP_005159761|]
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uncharacterized protein [Danio rerio]

Protein Classification

zf-FCS and DUF3504 domain-containing protein( domain architecture ID 10534342)

zf-FCS and DUF3504 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1184-1349 1.18e-75

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


:

Pssm-ID: 463430  Cd Length: 162  Bit Score: 247.57  E-value: 1.18e-75
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528510347  1184 IHSRVEEEFLWNCKQLGAFSPGVLLNTLIYFFTKYFNYRTVEQHRLLSFAHVKRYTRGPANAKVSFLRFYPPkedssDDG 1263
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPNPREKSTYLRYYEP-----PDQ 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528510347  1264 VPAKKRKKDDE-RQRVLKIGQNSDNPLHCPVRLYEFYLSKCSPGIRHHATKFYLSPERSCVPSSPTWFSISALSDEALDS 1342
Cdd:pfam12012   76 VETGGRKKRDEgVNKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRNTLES 155


                   ....*..
gi 528510347  1343 MLSRILT 1349
Cdd:pfam12012  156 MLTRILL 162
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 350-390 1.40e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.74  E-value: 1.40e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 528510347   350 LNMNSCVNCGGFCYGTDAQCPsLRMEDRVMKFCSQTCLTAY 390
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIV-LQNDGSVGQFCSQSCLDSY 40
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1184-1349 1.18e-75

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 247.57  E-value: 1.18e-75
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528510347  1184 IHSRVEEEFLWNCKQLGAFSPGVLLNTLIYFFTKYFNYRTVEQHRLLSFAHVKRYTRGPANAKVSFLRFYPPkedssDDG 1263
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPNPREKSTYLRYYEP-----PDQ 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528510347  1264 VPAKKRKKDDE-RQRVLKIGQNSDNPLHCPVRLYEFYLSKCSPGIRHHATKFYLSPERSCVPSSPTWFSISALSDEALDS 1342
Cdd:pfam12012   76 VETGGRKKRDEgVNKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRNTLES 155


                   ....*..
gi 528510347  1343 MLSRILT 1349
Cdd:pfam12012  156 MLTRILL 162
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 350-390 1.40e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.74  E-value: 1.40e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 528510347   350 LNMNSCVNCGGFCYGTDAQCPsLRMEDRVMKFCSQTCLTAY 390
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIV-LQNDGSVGQFCSQSCLDSY 40
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1184-1349 1.18e-75

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 247.57  E-value: 1.18e-75
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528510347  1184 IHSRVEEEFLWNCKQLGAFSPGVLLNTLIYFFTKYFNYRTVEQHRLLSFAHVKRYTRGPANAKVSFLRFYPPkedssDDG 1263
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPNPREKSTYLRYYEP-----PDQ 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528510347  1264 VPAKKRKKDDE-RQRVLKIGQNSDNPLHCPVRLYEFYLSKCSPGIRHHATKFYLSPERSCVPSSPTWFSISALSDEALDS 1342
Cdd:pfam12012   76 VETGGRKKRDEgVNKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRNTLES 155


                   ....*..
gi 528510347  1343 MLSRILT 1349
Cdd:pfam12012  156 MLTRILL 162
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 350-390 1.40e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.74  E-value: 1.40e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 528510347   350 LNMNSCVNCGGFCYGTDAQCPsLRMEDRVMKFCSQTCLTAY 390
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIV-LQNDGSVGQFCSQSCLDSY 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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