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Conserved domains on  [gi|460384808|ref|XP_004238100|]
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transcription initiation factor TFIID subunit 4b [Solanum lycopersicum]

Protein Classification

TAF4-like domain-containing protein( domain architecture ID 11192536)

TAF4-like domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TAF4 pfam05236
Transcription initiation factor TFIID component TAF4 family; This region of similarity is ...
 622-920 7.93e-89

Transcription initiation factor TFIID component TAF4 family; This region of similarity is found in Transcription initiation factor TFIID component TAF4.


:

Pssm-ID: 461598 [Multi-domain]  Cd Length: 264  Bit Score: 283.78  E-value: 7.93e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460384808  622 LNDVTAVSGVNLREEEEQLFSGPkEDSRVSEASRRVVQEEEERLILQKIPLQKKLTEIMAKCGLKSMSSDVERCLSLCVE 701
Cdd:pfam05236   1 LNDVLAMAGVNLREEEERLLSSQ-EASTNSEAVGTVVRSCKDEPFLNPYPLQRKILEIAKKNGLKEIDPDVLELLSHACE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460384808  702 ERMRGLISSLIRLSKQRVDIEKSRHRTIVTSDVREEIMSINRKAREEWERKQA-DVEKLQKANEpEGSTGVDGDKEKDEG 780
Cdd:pfam05236  80 ERLRNLLEKLIVISRHRRDGEKTDHRYEQTSDVRKQLKFLAQKDKEEEERRVAeEREGLLKAAK-SRSNQEDPEQLKLKQ 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460384808  781 RGKSikVNKEEDDKMRTTAANVAAraavggddmlskwqLMAEQARQKREGGGD-VASGSQPGKDVTRKNLPAPPRSSRDP 859
Cdd:pfam05236 159 EAKE--MQKEEDEKMRHRAANLTA--------------LAAIGPRKKKYSWMSsSASGSGGGGSGSSKPSSSSGSSSKGT 222

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 460384808  860 QeaekRIQSSAIAPpgvvrravrtqgiitQTRIARSITVKDVIAVLEREPQMSKSTLIYRL 920
Cdd:pfam05236 223 S----QTQSSAISR---------------EARRIKRVTLRDLLFALEQEREGSRSALLYGY 264
RST pfam12174
RCD1-SRO-TAF4 (RST) plant domain; This domain is found in plant RCD1, SRO and TAF4 proteins, ...
 214-276 6.15e-22

RCD1-SRO-TAF4 (RST) plant domain; This domain is found in plant RCD1, SRO and TAF4 proteins, hence its name of RST. It is required for interaction with multiple plant transcription factors. Radical-Induced Cell Death1 (RCD1) is an important regulator of stress and hormonal and developmental responses in Arabidopsis thaliana, as is its closest homolog, SRO1 - Similar To RCD-One1. TBP-Associated Factor 4 (TAF4) and TAF4-b are components of the transcription initiation factor complex TFIID.


:

Pssm-ID: 432383  Cd Length: 67  Bit Score: 89.86  E-value: 6.15e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 460384808  214 KQVPFAMLFPHIQPQLDKDRAAQLQTLYVKLKKNEISKESFVRNMRSIIGDQMLKMAVYKFQS 276
Cdd:pfam12174   5 PWMPFPMLLSALSKKLPPSDMDLLQKHYEDFKEKKISREEFVRKLRQIVGDQLLKSTIKSLQQ 67
 
Name Accession Description Interval E-value
TAF4 pfam05236
Transcription initiation factor TFIID component TAF4 family; This region of similarity is ...
 622-920 7.93e-89

Transcription initiation factor TFIID component TAF4 family; This region of similarity is found in Transcription initiation factor TFIID component TAF4.


Pssm-ID: 461598 [Multi-domain]  Cd Length: 264  Bit Score: 283.78  E-value: 7.93e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460384808  622 LNDVTAVSGVNLREEEEQLFSGPkEDSRVSEASRRVVQEEEERLILQKIPLQKKLTEIMAKCGLKSMSSDVERCLSLCVE 701
Cdd:pfam05236   1 LNDVLAMAGVNLREEEERLLSSQ-EASTNSEAVGTVVRSCKDEPFLNPYPLQRKILEIAKKNGLKEIDPDVLELLSHACE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460384808  702 ERMRGLISSLIRLSKQRVDIEKSRHRTIVTSDVREEIMSINRKAREEWERKQA-DVEKLQKANEpEGSTGVDGDKEKDEG 780
Cdd:pfam05236  80 ERLRNLLEKLIVISRHRRDGEKTDHRYEQTSDVRKQLKFLAQKDKEEEERRVAeEREGLLKAAK-SRSNQEDPEQLKLKQ 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460384808  781 RGKSikVNKEEDDKMRTTAANVAAraavggddmlskwqLMAEQARQKREGGGD-VASGSQPGKDVTRKNLPAPPRSSRDP 859
Cdd:pfam05236 159 EAKE--MQKEEDEKMRHRAANLTA--------------LAAIGPRKKKYSWMSsSASGSGGGGSGSSKPSSSSGSSSKGT 222

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 460384808  860 QeaekRIQSSAIAPpgvvrravrtqgiitQTRIARSITVKDVIAVLEREPQMSKSTLIYRL 920
Cdd:pfam05236 223 S----QTQSSAISR---------------EARRIKRVTLRDLLFALEQEREGSRSALLYGY 264
HFD_TAF4 cd08045
histone-fold domain found in transcription initiation factor TFIID subunit 4 (TAF4) and ...
 663-754 4.39e-32

histone-fold domain found in transcription initiation factor TFIID subunit 4 (TAF4) and similar proteins; TAF4, also called TATA Binding Protein (TBP) associated factor 4, RNA polymerase II TBP-associated factor subunit C, TBP-associated factor 4, transcription initiation factor TFIID 130 kDa subunit (TAF(II)130, TAFII-130, TAFII130), or transcription initiation factor TFIID 135 kDa subunit (TAF(II)135, TAFII-135, TAFII135), is a component of the TFIID complex that is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TFIID is one of the general transcription factors required for accurate and regulated initiation by RNA polymerase II. It plays a central role in mediating promoter responses to various activators and repressors. TAF4 potentiates transcriptional activation by the AF-2S of retinoic acid, vitamin D3 and thyroid hormone. TAF4 also acts as a component of the TFTC-HAT complex and some MLL1/MLL complexes. TAF4 interacts with ATF7 and the interaction inhibits ATF7-mediated transactivation.


Pssm-ID: 467027 [Multi-domain]  Cd Length: 100  Bit Score: 120.03  E-value: 4.39e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460384808 663 ERLILQKIPLQKKLTEIMAKCGLKSMSSDVERCLSLCVEERMRGLISSLIRLSKQRVDIEKSRHRTIVTSDVREEIMSIN 742
Cdd:cd08045    1 EESFLNPPPLQKKIQKIAKKHGLKEVSPDVLSLLSLAVQERLRDLLEKLIVASKHRVDSEKPDYRYEVTSDVRRQLKALE 80

                         90
                 ....*....|..
gi 460384808 743 RKAREEWERKQA 754
Cdd:cd08045   81 RLEREEEERRRE 92
RST pfam12174
RCD1-SRO-TAF4 (RST) plant domain; This domain is found in plant RCD1, SRO and TAF4 proteins, ...
 214-276 6.15e-22

RCD1-SRO-TAF4 (RST) plant domain; This domain is found in plant RCD1, SRO and TAF4 proteins, hence its name of RST. It is required for interaction with multiple plant transcription factors. Radical-Induced Cell Death1 (RCD1) is an important regulator of stress and hormonal and developmental responses in Arabidopsis thaliana, as is its closest homolog, SRO1 - Similar To RCD-One1. TBP-Associated Factor 4 (TAF4) and TAF4-b are components of the transcription initiation factor complex TFIID.


Pssm-ID: 432383  Cd Length: 67  Bit Score: 89.86  E-value: 6.15e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 460384808  214 KQVPFAMLFPHIQPQLDKDRAAQLQTLYVKLKKNEISKESFVRNMRSIIGDQMLKMAVYKFQS 276
Cdd:pfam12174   5 PWMPFPMLLSALSKKLPPSDMDLLQKHYEDFKEKKISREEFVRKLRQIVGDQLLKSTIKSLQQ 67
 
Name Accession Description Interval E-value
TAF4 pfam05236
Transcription initiation factor TFIID component TAF4 family; This region of similarity is ...
 622-920 7.93e-89

Transcription initiation factor TFIID component TAF4 family; This region of similarity is found in Transcription initiation factor TFIID component TAF4.


Pssm-ID: 461598 [Multi-domain]  Cd Length: 264  Bit Score: 283.78  E-value: 7.93e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460384808  622 LNDVTAVSGVNLREEEEQLFSGPkEDSRVSEASRRVVQEEEERLILQKIPLQKKLTEIMAKCGLKSMSSDVERCLSLCVE 701
Cdd:pfam05236   1 LNDVLAMAGVNLREEEERLLSSQ-EASTNSEAVGTVVRSCKDEPFLNPYPLQRKILEIAKKNGLKEIDPDVLELLSHACE 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460384808  702 ERMRGLISSLIRLSKQRVDIEKSRHRTIVTSDVREEIMSINRKAREEWERKQA-DVEKLQKANEpEGSTGVDGDKEKDEG 780
Cdd:pfam05236  80 ERLRNLLEKLIVISRHRRDGEKTDHRYEQTSDVRKQLKFLAQKDKEEEERRVAeEREGLLKAAK-SRSNQEDPEQLKLKQ 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460384808  781 RGKSikVNKEEDDKMRTTAANVAAraavggddmlskwqLMAEQARQKREGGGD-VASGSQPGKDVTRKNLPAPPRSSRDP 859
Cdd:pfam05236 159 EAKE--MQKEEDEKMRHRAANLTA--------------LAAIGPRKKKYSWMSsSASGSGGGGSGSSKPSSSSGSSSKGT 222

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 460384808  860 QeaekRIQSSAIAPpgvvrravrtqgiitQTRIARSITVKDVIAVLEREPQMSKSTLIYRL 920
Cdd:pfam05236 223 S----QTQSSAISR---------------EARRIKRVTLRDLLFALEQEREGSRSALLYGY 264
HFD_TAF4 cd08045
histone-fold domain found in transcription initiation factor TFIID subunit 4 (TAF4) and ...
 663-754 4.39e-32

histone-fold domain found in transcription initiation factor TFIID subunit 4 (TAF4) and similar proteins; TAF4, also called TATA Binding Protein (TBP) associated factor 4, RNA polymerase II TBP-associated factor subunit C, TBP-associated factor 4, transcription initiation factor TFIID 130 kDa subunit (TAF(II)130, TAFII-130, TAFII130), or transcription initiation factor TFIID 135 kDa subunit (TAF(II)135, TAFII-135, TAFII135), is a component of the TFIID complex that is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). TFIID is one of the general transcription factors required for accurate and regulated initiation by RNA polymerase II. It plays a central role in mediating promoter responses to various activators and repressors. TAF4 potentiates transcriptional activation by the AF-2S of retinoic acid, vitamin D3 and thyroid hormone. TAF4 also acts as a component of the TFTC-HAT complex and some MLL1/MLL complexes. TAF4 interacts with ATF7 and the interaction inhibits ATF7-mediated transactivation.


Pssm-ID: 467027 [Multi-domain]  Cd Length: 100  Bit Score: 120.03  E-value: 4.39e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 460384808 663 ERLILQKIPLQKKLTEIMAKCGLKSMSSDVERCLSLCVEERMRGLISSLIRLSKQRVDIEKSRHRTIVTSDVREEIMSIN 742
Cdd:cd08045    1 EESFLNPPPLQKKIQKIAKKHGLKEVSPDVLSLLSLAVQERLRDLLEKLIVASKHRVDSEKPDYRYEVTSDVRRQLKALE 80

                         90
                 ....*....|..
gi 460384808 743 RKAREEWERKQA 754
Cdd:cd08045   81 RLEREEEERRRE 92
RST pfam12174
RCD1-SRO-TAF4 (RST) plant domain; This domain is found in plant RCD1, SRO and TAF4 proteins, ...
 214-276 6.15e-22

RCD1-SRO-TAF4 (RST) plant domain; This domain is found in plant RCD1, SRO and TAF4 proteins, hence its name of RST. It is required for interaction with multiple plant transcription factors. Radical-Induced Cell Death1 (RCD1) is an important regulator of stress and hormonal and developmental responses in Arabidopsis thaliana, as is its closest homolog, SRO1 - Similar To RCD-One1. TBP-Associated Factor 4 (TAF4) and TAF4-b are components of the transcription initiation factor complex TFIID.


Pssm-ID: 432383  Cd Length: 67  Bit Score: 89.86  E-value: 6.15e-22
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 460384808  214 KQVPFAMLFPHIQPQLDKDRAAQLQTLYVKLKKNEISKESFVRNMRSIIGDQMLKMAVYKFQS 276
Cdd:pfam12174   5 PWMPFPMLLSALSKKLPPSDMDLLQKHYEDFKEKKISREEFVRKLRQIVGDQLLKSTIKSLQQ 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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