|
Name |
Accession |
Description |
Interval |
E-value |
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
309-975 |
1.36e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 78.56 E-value: 1.36e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 309 AEDDVEKLRGEIGTLTRKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRREcegLRGTKKTIHDANGSGKR 388
Cdd:TIGR02168 244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQ---KQILRERLANLERQLEE 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 389 LSDGEDPWSQ--------VEELKQELGHEKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEEtvEDHQ 460
Cdd:TIGR02168 321 LEAQLEELESkldelaeeLAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQ--IASL 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 461 EAQYEHALSNVHTAGHKID--MSETSSYQGKEDELMLDALVKKSDGI---------ASSELEEKIVELSDEIELYKRDRE 529
Cdd:TIGR02168 399 NNEIERLEARLERLEDRRErlQQEIEELLKKLEEAELKELQAELEELeeeleelqeELERLEEALEELREELEEAEQALD 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 530 DLEMQMEQLALDYEILK--QENHDISSRLEQTQLREQLRMqyecSAHLSIISDLEANVENLENELQAQskrLEADIAEVL 607
Cdd:TIGR02168 479 AAERELAQLQARLDSLErlQENLEGFSEGVKALLKNQSGL----SGILGVLSELISVDEGYEAAIEAA---LGGRLQAVV 551
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 608 aakVEQEKRAIKAEESLRKARWNNATTAE-RLQEEFKSLSSQVSSAFSANERLLVQARKEAAELQLQKSqLEELVQKAH- 685
Cdd:TIGR02168 552 ---VENLNAAKKAIAFLKQNELGRVTFLPlDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA-LSYLLGGVLv 627
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 686 -EDIASVQEQHRmKIQQLLTLVD-------------FKSNETERLVMELKSKTDEFQNQKRCDEAKLNALSEEIDKLKTR 751
Cdd:TIGR02168 628 vDDLDNALELAK-KLRPGYRIVTldgdlvrpggvitGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 752 IAKLSDERDNLLEKNEKKDMELAANGEKDMVLQDK----TAVIALLNKEVTLLKDQVQTYLEELHTLKHSKNEKDEVIGK 827
Cdd:TIGR02168 707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEveqlEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 828 LQIDIGSLKLQYDNVKNLLSTKESEKSNLASQVLKLRRALESREgvKENGVTSDAKDNQHSNSKRIKHDTGStgssyapp 907
Cdd:TIGR02168 787 LEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE--RRIAATERRLEDLEEQIEELSEDIES-------- 856
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 357146931 908 stdrhdanddcNEHSMRGAGAHADQSTKELDSLKEMNKAMQEELMELHERYSEISLKFAEVEGERQQL 975
Cdd:TIGR02168 857 -----------LAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL 913
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
509-872 |
9.74e-14 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 75.87 E-value: 9.74e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 509 ELEEKIVELSDEIELYKRDREDlemqmeqlALDYEILKQENHDISSRLeqtQLREQLRMQYECSAHLSIISDLEANVENL 588
Cdd:TIGR02169 188 RLDLIIDEKRQQLERLRREREK--------AERYQALLKEKREYEGYE---LLKEKEALERQKEAIERQLASLEEELEKL 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 589 ENELQAQSKRLEAdiAEVLAAKVEQEKRAIKAEESLRkarwnnattaerLQEEFKSLSSQVSSAFSANERLLVQARKEAA 668
Cdd:TIGR02169 257 TEEISELEKRLEE--IEQLLEELNKKIKDLGEEEQLR------------VKEKIGELEAEIASLERSIAEKERELEDAEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 669 ELQLQKSQLEELvQKAHEDIASVQEQHRMKIQQLLTLVDFKSNETERLVMELKSKTDEFQNQKRcdeaKLNALSEEIDKL 748
Cdd:TIGR02169 323 RLAKLEAEIDKL-LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRD----ELKDYREKLEKL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 749 KTRIAKLSDERDNLLEKNEKKDMELAangEKDMVLQDKTAVIALLNKEVTLLKDQVQTYLEELHTLKhsknekdEVIGKL 828
Cdd:TIGR02169 398 KREINELKRELDRLQEELQRLSEELA---DLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLA-------ADLSKY 467
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 357146931 829 QIDIGSLKLQYDNVKNLLSTKESEksnlASQVLKLRRALESREG 872
Cdd:TIGR02169 468 EQELYDLKEEYDRVEKELSKLQRE----LAEAEAQARASEERVR 507
|
|
| NT-C2 |
pfam10358 |
N-terminal C2 in EEIG1 and EHBP1 proteins; This version of the C2 domain was initally ... |
13-139 |
1.28e-12 |
|
N-terminal C2 in EEIG1 and EHBP1 proteins; This version of the C2 domain was initally identified in the vertebrate estrogen early-induced gene 1 (EEIG1), and its Drosophila ortholog required for uptake of dsRNA via the endocytotic machinery to induce RNAi silencing. It is also in C.elegans ortholog Sym-3 (SYnthetic lethal with Mec-3) and the mammalian protein EHBP1 (EH domain Binding Protein-1) that regulates endocytotic recycling and two plant proteins, RPG that regulates Rhizobium-directed polar growth and PMI1 (Plastid Movement Impaired 1) that is essential for intracellular movement of chloroplasts in response to blue light.
Pssm-ID: 463058 Cd Length: 143 Bit Score: 66.19 E-value: 1.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 13 KAKAVFKLQFHATQVPELGWESMMVVVTPQDVGRPTARSERAEVAGGACRWAAPIFEATKL-PNPGKAAAGDKIYKFLVY 91
Cdd:pfam10358 4 KPKFQFVLTIHELQNLPLVGGELFVKWRRGDKKGSSGTTEKALVNNGRAIFNEEFSIPVTLfLDKKGGKYEEKLLEFSVY 83
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 357146931 92 -ETGSSKAALLGEATANLAEYA-EAFKPSAVTLPLKGSPAPGALLHVTIQ 139
Cdd:pfam10358 84 kVTKKGKKKVLGKASIDLAEYAnLKKKPTTVRFLLKKSSKKNATLSLSIQ 133
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
509-775 |
1.49e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 71.89 E-value: 1.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 509 ELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQLREQLRMQyecsAHLSIISDLEANVENL 588
Cdd:COG1196 236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA----ELARLEQDIARLEERR 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 589 EnELQAQSKRLEADIAEVL-------AAKVEQEKRAIKAEESLRKARWNNATTAERLQEEFKSLSSQVSSAFSANERLLv 661
Cdd:COG1196 312 R-ELEERLEELEEELAELEeeleeleEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL- 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 662 QARKEAAELQLQKSQLEELVQKAHEDIASVQEQHRMKIQQLLtlvdfksnETERLVMELKSKTDEFQNQKRCDEAKLNAL 741
Cdd:COG1196 390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA--------ELEEEEEEEEEALEEAAEEEAELEEEEEAL 461
|
250 260 270
....*....|....*....|....*....|....
gi 357146931 742 SEEIDKLKTRIAKLSDERDNLLEKNEKKDMELAA 775
Cdd:COG1196 462 LELLAELLEEAALLEAALAELLEELAEAAARLLL 495
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
414-764 |
1.47e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.93 E-value: 1.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 414 ADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETVEDHQEaqyehalsnVHTAGHKIDMSETSSYQGKEDEL 493
Cdd:TIGR02168 680 EELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ---------ISALRKDLARLEAEVEQLEERIA 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 494 MLDALVKKSDGIASsELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQlREQLRMQYECSA 573
Cdd:TIGR02168 751 QLSKELTELEAEIE-ELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLN-EEAANLRERLES 828
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 574 HLSIISDLEANVENLENELQAQSKRLEADIAEVLAAKVEQEKrAIKAEESLRKARWNNATTAERLQEEFKSLSSQVSSAf 653
Cdd:TIGR02168 829 LERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEE-LESELEALLNERASLEEALALLRSELEELSEELREL- 906
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 654 sanERLLVQARKEAAELQLQKSQLEELVQKAHEDIASVQEQHRMKIQQLLTLVDFKSNETERLVMELKSKTDEFQNQ-KR 732
Cdd:TIGR02168 907 ---ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKiKE 983
|
330 340 350
....*....|....*....|....*....|..
gi 357146931 733 CDEAKLNALsEEIDKLKTRIAKLSDERDNLLE 764
Cdd:TIGR02168 984 LGPVNLAAI-EEYEELKERYDFLTAQKEDLTE 1014
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
310-870 |
3.25e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 67.45 E-value: 3.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 310 EDDVEKLRGEIgtlTRKLDVSDMELQTLRKQIVKEsrrgHDLskEMSSLREERDALRRECEGLRGTKKTIHDA--NGSGK 387
Cdd:pfam15921 244 EDQLEALKSES---QNKIELLLQQHQDRIEQLISE----HEV--EITGLTEKASSARSQANSIQSQLEIIQEQarNQNSM 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 388 RLSDGEDPWSQVEELKQELGHEKNLNADlrlqlqKMQESNSELLLAVKDLDEVLEQKNReisILQEETVEDHQeaqYEHA 467
Cdd:pfam15921 315 YMRQLSDLESTVSQLRSELREAKRMYED------KIEELEKQLVLANSELTEARTERDQ---FSQESGNLDDQ---LQKL 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 468 LSNVHTAGHKIdmsetsSYQGKEDELMLDALVKKSDGI--ASSELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEIL 545
Cdd:pfam15921 383 LADLHKREKEL------SLEKEQNKRLWDRDTGNSITIdhLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGK 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 546 KQENHDISS---RLEQTqlREQLR-MQYECSAHLSIISDLEANVENLENELQAQSKRLEADIAEV--LAAKVE---QEKR 616
Cdd:pfam15921 457 NESLEKVSSltaQLEST--KEMLRkVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEItkLRSRVDlklQELQ 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 617 AIKAE-ESLRKARwnNATTAERLQEEFKSLSSQVSSAFSANERLLV-QARKEAAELQLQKSQLEELVQKAH---EDIASV 691
Cdd:pfam15921 535 HLKNEgDHLRNVQ--TECEALKLQMAEKDKVIEILRQQIENMTQLVgQHGRTAGAMQVEKAQLEKEINDRRlelQEFKIL 612
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 692 QEQHRMKIQQL--------LTLVDFKSNETERL--VMELKSKTDEFQNQKRCDEAKLNALSEEIDKLKTRIAKLSDERD- 760
Cdd:pfam15921 613 KDKKDAKIRELearvsdleLEKVKLVNAGSERLraVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMEt 692
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 761 --NLLE---KNEKKDMELAANGEKDMVLQDKTAV-IAL-LNKEVTLLKDQVQTYLEELHTLkhsknekDEVIGKLQIDIG 833
Cdd:pfam15921 693 ttNKLKmqlKSAQSELEQTRNTLKSMEGSDGHAMkVAMgMQKQITAKRGQIDALQSKIQFL-------EEAMTNANKEKH 765
|
570 580 590
....*....|....*....|....*....|....*..
gi 357146931 834 SLKLQYDNVKNLLSTKESEKSNLASQvLKLRRALESR 870
Cdd:pfam15921 766 FLKEEKNKLSQELSTVATEKNKMAGE-LEVLRSQERR 801
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
615-871 |
5.87e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.00 E-value: 5.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 615 KRAIKAEESLRKARWNnattAERLQEEFKSLSSQVSS----AFSANERLLVQARKEAAELQLQKSQLEELVQKAHE---D 687
Cdd:TIGR02168 172 ERRKETERKLERTREN----LDRLEDILNELERQLKSlerqAEKAERYKELKAELRELELALLVLRLEELREELEElqeE 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 688 IASVQEQHRmKIQQLLTLVDFKSNETERLVMELKSKTDEFQnqkrcdeAKLNALSEEIDKLKTRIAKLSDERDNLLEKNE 767
Cdd:TIGR02168 248 LKEAEEELE-ELTAELQELEEKLEELRLEVSELEEEIEELQ-------KELYALANEISRLEQQKQILRERLANLERQLE 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 768 KKDMELAANGEKDMVLQDKTA----VIALLNKEVTLLKDQVQTYLEELHTLKHSKNEKDEVIGKLQIDIGSLKLQYDNVK 843
Cdd:TIGR02168 320 ELEAQLEELESKLDELAEELAeleeKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN 399
|
250 260
....*....|....*....|....*...
gi 357146931 844 NLLSTKESEKSNLASQVLKLRRALESRE 871
Cdd:TIGR02168 400 NEIERLEARLERLEDRRERLQQEIEELL 427
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
309-836 |
3.48e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.19 E-value: 3.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 309 AEDDVEKLRGEIGTLTRKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDAL----RRECEGLRGTKKTIHDANG 384
Cdd:COG1196 244 LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLeqdiARLEERRRELEERLEELEE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 385 SGKRLSDGEDpwSQVEELKQELGHEKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETVEDHQEAQY 464
Cdd:COG1196 324 ELAELEEELE--ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQ 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 465 EHALSNVHtAGHKIDMSETSSYQGKEDELMLDALVKKSDGIAS-SELEEKIVELSDEIELYKRDREDLEMQMEQLALDYE 543
Cdd:COG1196 402 LEELEEAE-EALLERLERLEEELEELEEALAELEEEEEEEEEAlEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 544 ILKQENHDISSRLEQTQLREQLRMQYECSAHLSIISDLEANVENLENELQAQSKRLEADIAEVLAAK-----VEQEKRAI 618
Cdd:COG1196 481 ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAlqnivVEDDEVAA 560
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 619 KAEESLRKARWNNATT-AERLQEEFKSLSSQVSSAFSANERLLVQARKEAAELQLQKSQLEELVQkahediASVQEQHRM 697
Cdd:COG1196 561 AAIEYLKAAKAGRATFlPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGR------TLVAARLEA 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 698 KIQQLLTLVDFKSNETERLVMELKSKTDEFQNQKRCDEAKLNALSEEIDKLKTRIAKLSDERDNLLEKNEKKDMELAANG 777
Cdd:COG1196 635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*....
gi 357146931 778 EKDMVLQDKTAVIALLNKEVTLLKDQVQTYLEELHTLKHSKNEKDEVIGKLQIDIGSLK 836
Cdd:COG1196 715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
509-762 |
4.21e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.92 E-value: 4.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 509 ELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQLREQlrmqyecsAHLSIISDLEANVENL 588
Cdd:TIGR02168 236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELY--------ALANEISRLEQQKQIL 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 589 ENE---LQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKARwNNATTAERLQEEFKSLSSQVSSAFSANERLLVQARK 665
Cdd:TIGR02168 308 RERlanLERQLEELEAQLEELESKLDELAEELAELEEKLEELK-EELESLEAELEELEAELEELESRLEELEEQLETLRS 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 666 EAAELQLQ-----------KSQLEELvQKAHEDIASVQEQHRMKIQQL-LTLVDFKSNETERLVMELKSKTDEFQNQKRC 733
Cdd:TIGR02168 387 KVAQLELQiaslnneierlEARLERL-EDRRERLQQEIEELLKKLEEAeLKELQAELEELEEELEELQEELERLEEALEE 465
|
250 260
....*....|....*....|....*....
gi 357146931 734 DEAKLNALSEEIDKLKTRIAKLSDERDNL 762
Cdd:TIGR02168 466 LREELEEAEQALDAAERELAQLQARLDSL 494
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
508-862 |
8.74e-10 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 62.73 E-value: 8.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 508 SELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQLreqlrmqyECSAHLSIISDLEANVEN 587
Cdd:TIGR04523 221 SELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQK--------ELEQNNKKIKELEKQLNQ 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 588 LENELQAQSKRLEADIAEVLA---AKVEQEKRAIKAE---------------ESLRKARWNNATTAERLQEEFKSLSSQV 649
Cdd:TIGR04523 293 LKSEISDLNNQKEQDWNKELKselKNQEKKLEEIQNQisqnnkiisqlneqiSQLKKELTNSESENSEKQRELEEKQNEI 372
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 650 SSAFSANERLLVQARK---EAAELQLQKSQLEELVQKAHEDIASVQEQHRMK---IQQLLTLVDFKSNETERL------- 716
Cdd:TIGR04523 373 EKLKKENQSYKQEIKNlesQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLekeIERLKETIIKNNSEIKDLtnqdsvk 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 717 ---VMELKSKTDEFQNQKRCDEAKLNALSEEIDKLKTRIAKLSDERDNLLEKN---EKKDMELAANGEKDMVLQDK-TAV 789
Cdd:TIGR04523 453 eliIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKkelEEKVKDLTKKISSLKEKIEKlESE 532
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 357146931 790 IALLNKEVTLLKDQVQTYLEEL--HTLKHSKNEKDEVIGKLQIDIGSLKLQYDNVKNLLSTKESEKSNLASQVLK 862
Cdd:TIGR04523 533 KKEKESKISDLEDELNKDDFELkkENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEE 607
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
310-974 |
1.42e-09 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 62.44 E-value: 1.42e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 310 EDDVEKLRGEIGTLTRKLDVSDmELQTLRKQIVKESRRghDLSKEMSSLREERDAL----RREC---EGLRGT-KKTIHD 381
Cdd:pfam15921 77 ERVLEEYSHQVKDLQRRLNESN-ELHEKQKFYLRQSVI--DLQTKLQEMQMERDAMadirRRESqsqEDLRNQlQNTVHE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 382 ANGSGKRLSDG-EDPWSQVEEL-KQELGHEKNLNaDLRLQL--------QKMQESNSELLLAVKDL----DEVLEQKNRE 447
Cdd:pfam15921 154 LEAAKCLKEDMlEDSNTQIEQLrKMMLSHEGVLQ-EIRSILvdfeeasgKKIYEHDSMSTMHFRSLgsaiSKILRELDTE 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 448 ISILQEET--VEDHQEAQYEHALSNVHT--AGHKIDMSETSSyqgkEDELMLDALVKKSDGIAS------SELEEKIVEL 517
Cdd:pfam15921 233 ISYLKGRIfpVEDQLEALKSESQNKIELllQQHQDRIEQLIS----EHEVEITGLTEKASSARSqansiqSQLEIIQEQA 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 518 SDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQ---------TQLREQLRMQYECSAHLS-IISDLEANVEN 587
Cdd:pfam15921 309 RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKqlvlanselTEARTERDQFSQESGNLDdQLQKLLADLHK 388
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 588 LENEL---QAQSKRL----------------EADIAEVLAAKVEQEKRAIKAEESLRKARWNNATTAErlQEEFKSLSSQ 648
Cdd:pfam15921 389 REKELsleKEQNKRLwdrdtgnsitidhlrrELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGK--NESLEKVSSL 466
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 649 VSSAFSANERLlvqaRKEAAELQLQKSQLEELVQKAHEDIASVQEQHRM------KIQQLLTLVDFKSNETErlvmELKS 722
Cdd:pfam15921 467 TAQLESTKEML----RKVVEELTAKKMTLESSERTVSDLTASLQEKERAieatnaEITKLRSRVDLKLQELQ----HLKN 538
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 723 KTDEFQN-QKRCDEAKLNALSEE--IDKLKTRIAKLSD--------------ERDNLLEKNEKKDMELaangEKDMVLQD 785
Cdd:pfam15921 539 EGDHLRNvQTECEALKLQMAEKDkvIEILRQQIENMTQlvgqhgrtagamqvEKAQLEKEINDRRLEL----QEFKILKD 614
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 786 KT-AVIALLNKEVTLLKDQ----VQTYLEELHTLKHSKNEKDEVIGKLQI---DIGSLKLQYDNVKNLLSTKeSEKSNLA 857
Cdd:pfam15921 615 KKdAKIRELEARVSDLELEkvklVNAGSERLRAVKDIKQERDQLLNEVKTsrnELNSLSEDYEVLKRNFRNK-SEEMETT 693
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 858 SQVLKL------------RRALESREGVKENGVTSDAKDNQHSNSKRIKHDTGSTGSSY-----APPSTDRHDANDDCNE 920
Cdd:pfam15921 694 TNKLKMqlksaqseleqtRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFleeamTNANKEKHFLKEEKNK 773
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*...
gi 357146931 921 HS--MRGAGAHADQSTKELDSLKEMNKAMQEELMELHERYSEISLKFAEVEG--ERQQ 974
Cdd:pfam15921 774 LSqeLSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDiiQRQE 831
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
299-642 |
1.54e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 62.00 E-value: 1.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 299 SNSGETGLGGAEDDVEKLRGEIGTLTRKLDVSDMELQTLRKQ-------IVKESRRGHDLSKEMSSLREERDALRRECEG 371
Cdd:TIGR02168 665 SAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEleeleeeLEQLRKELEELSRQISALRKDLARLEAEVEQ 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 372 LRGTKKTIHDANGSGKRLSDGEDpwSQVEELKQELGHEKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISIL 451
Cdd:TIGR02168 745 LEERIAQLSKELTELEAEIEELE--ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANL 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 452 QeETVEDHQEAQYEHALSNVHTAGHKIDMSET--------SSYQGKEDELmLDALVKKSDgiASSELEEKIVELSDEIEL 523
Cdd:TIGR02168 823 R-ERLESLERRIAATERRLEDLEEQIEELSEDieslaaeiEELEELIEEL-ESELEALLN--ERASLEEALALLRSELEE 898
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 524 YKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQLR-----EQLRMQYECSahLSIISDLEANVENLENELQAQSKR 598
Cdd:TIGR02168 899 LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRidnlqERLSEEYSLT--LEEAEALENKIEDDEEEARRRLKR 976
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 357146931 599 LEADIAEV----LAA-----KVEQEKRAIKAE-ESLRKARWN--------NATTAERLQEEF 642
Cdd:TIGR02168 977 LENKIKELgpvnLAAieeyeELKERYDFLTAQkEDLTEAKETleeaieeiDREARERFKDTF 1038
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
315-856 |
7.92e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 59.65 E-value: 7.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 315 KLRGEIGTLTRKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRGTKKTIHDANGSGKRLSdged 394
Cdd:TIGR04523 142 KFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLE---- 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 395 pwSQVEELKQElghEKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETVEDHQEAQyehALSNVHTA 474
Cdd:TIGR04523 218 --SQISELKKQ---NNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNK---KIKELEKQ 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 475 GHKIDMSETSSYQGKEDELM------LDALVKKSDGIAS--SELEEKIVELSDEIELYKRDREDLEMqmEQLALDYEI-- 544
Cdd:TIGR04523 290 LNQLKSEISDLNNQKEQDWNkelkseLKNQEKKLEEIQNqiSQNNKIISQLNEQISQLKKELTNSES--ENSEKQRELee 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 545 ----LKQENHDISSRLEQTQlreQLRMQyecsahlsiISDLEANVENLENE----------LQAQSKRLEADIAEVLAAK 610
Cdd:TIGR04523 368 kqneIEKLKKENQSYKQEIK---NLESQ---------INDLESKIQNQEKLnqqkdeqikkLQQEKELLEKEIERLKETI 435
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 611 VEQE---KRAIKAEESLRKARWNNATTAERLQEEFKSLSSQVSSAFS---ANERLLVQARKEAAELQLQKSQLEELVQKA 684
Cdd:TIGR04523 436 IKNNseiKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQnleQKQKELKSKEKELKKLNEEKKELEEKVKDL 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 685 HEDIASVQEqhrmKIQQLltlvdfkSNETERLVMELKSKTDEFQNQKrcDEAKLNALSEEIDKLKTRIAKLSDERDNLLE 764
Cdd:TIGR04523 516 TKKISSLKE----KIEKL-------ESEKKEKESKISDLEDELNKDD--FELKKENLEKEIDEKNKEIEELKQTQKSLKK 582
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 765 KNEkkdmelaangEKDMVLQDKTAVIALLNKEVTLLKDQVQTYLEELHTLKHSKNEKDEVIGKLQIDIGSLKLQYDNVKN 844
Cdd:TIGR04523 583 KQE----------EKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKE 652
|
570
....*....|..
gi 357146931 845 LLSTKESEKSNL 856
Cdd:TIGR04523 653 TIKEIRNKWPEI 664
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
560-872 |
8.75e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 59.57 E-value: 8.75e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 560 QLREQLRmQYECSAHLSIISDLEANVENLENELQAQSKRLEADIAEV--LAAKVEQEKRAIKAEEslrkarwnnaTTAER 637
Cdd:COG1196 217 ELKEELK-ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELaeLEAELEELRLELEELE----------LELEE 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 638 LQEEFKSLSSQVSsafsanerllvQARKEAAELQLQKSQLEELVQKAHEDIASVQEQHRMKIQQLLTLVDFKSNETERLV 717
Cdd:COG1196 286 AQAEEYELLAELA-----------RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 718 MELKSKTDEFQNQKRcDEAKLNALSEEIDKLKTRIAKLSDERDNLLEKNEKKDMELAANGEKDmvLQDKTAVIALLNKEV 797
Cdd:COG1196 355 EAEAELAEAEEALLE-AEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERL--ERLEEELEELEEALA 431
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 357146931 798 TLLKDQVQTyLEELHTLKHSKNEKDEVIGKLQIDIGSLKLQYDNVKNLLSTKESEKSNLASQVLKLRRALESREG 872
Cdd:COG1196 432 ELEEEEEEE-EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
308-757 |
2.19e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.54 E-value: 2.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 308 GAEDDVEKLRGEIGTLTRKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRGtkktihDANGSGK 387
Cdd:TIGR02169 664 GGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ------EEEKLKE 737
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 388 RLSDGEDpwsQVEELKQELGHEKNLNADLRLQLQKMQESNSELLLAVKDL-----DEVLEQKNREISILQEETVEdhQEA 462
Cdd:TIGR02169 738 RLEELEE---DLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSR--IEA 812
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 463 QYEHalsnvhtaghkIDMSETSSYQGKE--DELMLDALVKKSDgiasseLEEKIVELSDEIELYKRDREDLEMQMEQLal 540
Cdd:TIGR02169 813 RLRE-----------IEQKLNRLTLEKEylEKEIQELQEQRID------LKEQIKSIEKEIENLNGKKEELEEELEEL-- 873
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 541 dyeilkqenhdissRLEQTQLREQLrmqyecsahlsiiSDLEANVENLENELQAQSKRLEAdiaevLAAKVEQEKRAIKA 620
Cdd:TIGR02169 874 --------------EAALRDLESRL-------------GDLKKERDELEAQLRELERKIEE-----LEAQIEKKRKRLSE 921
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 621 EEslrkarwnnaTTAERLQEEFKSLSSQVSSAFSANERLL----VQARKEAAELQLQKsqLEELVQKAHEDIASVQEQHR 696
Cdd:TIGR02169 922 LK----------AKLEALEEELSEIEDPKGEDEEIPEEELsledVQAELQRVEEEIRA--LEPVNMLAIQEYEEVLKRLD 989
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 357146931 697 MKIQQLLTLvdfksnETERlvMELKSKTDEFQNQKRcdEAKLNALSEEIDKLKTRIAKLSD 757
Cdd:TIGR02169 990 ELKEKRAKL------EEER--KAILERIEEYEKKKR--EVFMEAFEAINENFNEIFAELSG 1040
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
520-986 |
2.46e-08 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 58.11 E-value: 2.46e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 520 EIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQLREQLRmQYECSAHLSI--ISDLEANVENLENELQAQSK 597
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKE-ELENELNLLEkeKLNIQKNIDKIKNKLLKLEL 201
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 598 RLEadiaeVLAAKVEQEKRAIKAEESLRKARWNNATTAERLQEEFKSLSSQVSSAFSANERLLVQARKEAAelQLQKSQL 677
Cdd:TIGR04523 202 LLS-----NLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK--QLSEKQK 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 678 EelVQKAHEDIASVQEQhrmkIQQLLT-LVDFKSNETERLVMELKSKTDEFQNQKRCDEAKLNALSEEIDKLKTRIAKLS 756
Cdd:TIGR04523 275 E--LEQNNKKIKELEKQ----LNQLKSeISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLK 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 757 DERDNLLEKNEKKDMELAangEKdmvlqdktaviallNKEVTLLKDQVQTYLEELHTLKHSKNE-------KDEVIGKLQ 829
Cdd:TIGR04523 349 KELTNSESENSEKQRELE---EK--------------QNEIEKLKKENQSYKQEIKNLESQINDleskiqnQEKLNQQKD 411
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 830 IDIGSLKLQYD----NVKNLLSTKESEKSNLASqvlklrraLESREGVKENGVTSdAKDNQHSNSKRIKHDTGSTGSsya 905
Cdd:TIGR04523 412 EQIKKLQQEKEllekEIERLKETIIKNNSEIKD--------LTNQDSVKELIIKN-LDNTRESLETQLKVLSRSINK--- 479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 906 ppstdrhdanddcNEHSMRGAGAHADQSTKELDSLKEMNKAMQEELMELHERYSEISLKFAEVEGERQQLVMTVRTLKNS 985
Cdd:TIGR04523 480 -------------IKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDE 546
|
.
gi 357146931 986 L 986
Cdd:TIGR04523 547 L 547
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
505-766 |
3.83e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 57.77 E-value: 3.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 505 IASSELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSrlEQTQLREQlrmqyecsahlsiISDLEAN 584
Cdd:TIGR02169 709 QELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS--ELKELEAR-------------IEELEED 773
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 585 VENLENELQAqskrLEADIAEVLAAKVEQEKRAIKAEESLRKARwnnattAERLQEEFKSLSSQVSSAFSANERLLVQAR 664
Cdd:TIGR02169 774 LHKLEEALND----LEARLSHSRIPEIQAELSKLEEEVSRIEAR------LREIEQKLNRLTLEKEYLEKEIQELQEQRI 843
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 665 keaaELQLQKSQLE---ELVQKAHEDIASVQEQHRMKIQQLltlvdfksneTERLVmELKSKTDEFQNQKRCDEAKLNAL 741
Cdd:TIGR02169 844 ----DLKEQIKSIEkeiENLNGKKEELEEELEELEAALRDL----------ESRLG-DLKKERDELEAQLRELERKIEEL 908
|
250 260
....*....|....*....|....*
gi 357146931 742 SEEIDKLKTRIAKLSDERDNLLEKN 766
Cdd:TIGR02169 909 EAQIEKKRKRLSELKAKLEALEEEL 933
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
333-845 |
1.58e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 55.43 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 333 ELQTLRKQIvkesrrgHDLSKEMSSLREERDALRRECEGLRGTKKTIHDANGSGKRLSDGEDPWSQVEELKQElgheknl 412
Cdd:PRK02224 252 ELETLEAEI-------EDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARRE------- 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 413 naDLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETVEDHQEAqyEHALSNVHTAGHKIDMSETssyqgkede 492
Cdd:PRK02224 318 --ELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEA--AELESELEEAREAVEDRRE--------- 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 493 lmldalvkksdgiASSELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQLR----EQLRMQ 568
Cdd:PRK02224 385 -------------EIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERveeaEALLEA 451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 569 YEC---------SAHLSIISDLEANVENLENELQAqskrLEADIAEVlAAKVEQEKRAIKAEESLRKARWNNATTAERLQ 639
Cdd:PRK02224 452 GKCpecgqpvegSPHVETIEEDRERVEELEAELED----LEEEVEEV-EERLERAEDLVEAEDRIERLEERREDLEELIA 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 640 EEFKSLSSQvssafsanERLLVQARKEAAELQLQKSQLEELVQKAHEDIASVQEqhrmkiqqlltlvdfKSNETERLVME 719
Cdd:PRK02224 527 ERRETIEEK--------RERAEELRERAAELEAEAEEKREAAAEAEEEAEEARE---------------EVAELNSKLAE 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 720 LKSKTDEFqnqkrcdeAKLNALSEEIDKLKTRIAKLSDERDNLLEKNEKKDMELAANGEKDMVLQDK---TAVIALLNKe 796
Cdd:PRK02224 584 LKERIESL--------ERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEfdeARIEEARED- 654
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 357146931 797 vtllKDQVQTYLEEL-HTLKHSKNEKDEvigkLQIDIGSLKLQYDNVKNL 845
Cdd:PRK02224 655 ----KERAEEYLEQVeEKLDELREERDD----LQAEIGAVENELEELEEL 696
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
325-628 |
2.33e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 54.94 E-value: 2.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 325 RKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRgtkKTIHDANGSGKRLSdgedpwSQVEELKQ 404
Cdd:COG1196 232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELE---LELEEAQAEEYELL------AELARLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 405 ELGHEKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEEtvEDHQEAQYEHALSNVHTAGHKIDMSETS 484
Cdd:COG1196 303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE--LEEAEAELAEAEEALLEAEAELAEAEEE 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 485 SYQGKEDELMLDAlvkksdgiASSELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQEnHDISSRLEQTQLREQ 564
Cdd:COG1196 381 LEELAEELLEALR--------AAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE-EEEEEEALEEAAEEE 451
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 357146931 565 LRMQYECSAHLSIISDLEANVENLENELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKAR 628
Cdd:COG1196 452 AELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
508-882 |
2.99e-07 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 54.59 E-value: 2.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 508 SELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENhdissRLEQTQLREQLRMQYECSAHLSIISDLEANVEN 587
Cdd:pfam02463 156 LEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKL-----QELKLKEQAKKALEYYQLKEKLELEEEYLLYLD 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 588 LENELQAQSKRLEADIAEvLAAKVEQEKRAIKAEESLRKARWNNATTAERLQEEFKSLSSQVSSAFSANERLLVQARKEA 667
Cdd:pfam02463 231 YLKLNEERIDLLQELLRD-EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRK 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 668 AELQLQKSQLEELVQKAHEDIASVQEQhRMKIQQLLTLVDFKSNETERLVMELKSKTDEFQNQKRCDEAKLNALSEEIDK 747
Cdd:pfam02463 310 VDDEEKLKESEKEKKKAEKELKKEKEE-IEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSS 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 748 lKTRIAKLSDERDNLLEKNEKKDMELAANgeKDMVLQDKTAVIALLNKEVTLLKDQVQTYLEELhtlkhsKNEKDEVIGK 827
Cdd:pfam02463 389 -AAKLKEEELELKSEEEKEAQLLLELARQ--LEDLLKEEKKEELEILEEEEESIELKQGKLTEE------KEELEKQELK 459
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 357146931 828 LQIDIGSLKLQYDNVKNLLSTKESEKSNLASQVLKLRRALESREGVKENGVTSDA 882
Cdd:pfam02463 460 LLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLA 514
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
420-756 |
6.01e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 53.82 E-value: 6.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 420 LQKMQESNSELLLAVKDLdEVLEQKNREISILQEETVEDHQEAQYEHALSNVHTAGHKIDMSE----TSSYQGKEDELM- 494
Cdd:TIGR00618 461 LQESAQSLKEREQQLQTK-EQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNpgplTRRMQRGEQTYAq 539
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 495 LDALVKKSDGIASSELEeKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLE-----QTQLREQLRMQY 569
Cdd:TIGR00618 540 LETSEEDVYHQLTSERK-QRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEklseaEDMLACEQHALL 618
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 570 ECSAHLSIISDLEANVENLENELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKARWNNATTAE------------- 636
Cdd:TIGR00618 619 RKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMqsekeqltywkem 698
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 637 -------------------RLQEEFKSLSSQVSSAFSANERLLVQARKEAAELQLQKSQLEELVQKAHEDIASVQEQHRM 697
Cdd:TIGR00618 699 laqcqtllrelethieeydREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGA 778
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357146931 698 KIQQLLTLVDFKSNETERLVMELKSKTDEFQNQKRCDEAKLNA----LSEEIDKLKTRIAKLS 756
Cdd:TIGR00618 779 ELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLqcetLVQEEEQFLSRLEEKS 841
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
312-829 |
6.22e-07 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 53.53 E-value: 6.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 312 DVEKLRGEIGTLTRKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREErdalRRECEGLRGTKKTIHDANGSGKRLSD 391
Cdd:PRK03918 232 ELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEK----VKELKELKEKAEEYIKLSEFYEEYLD 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 392 GEdpwsqvEELKQELGHEKNLNADLRLQLQKMQESNSELllavKDLDEVLEQKNREISILqEETVEDHQEAqyehalsnv 471
Cdd:PRK03918 308 EL------REIEKRLSRLEEEINGIEERIKELEEKEERL----EELKKKLKELEKRLEEL-EERHELYEEA--------- 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 472 htaghKIDMSETSSYQGKEDELMLDALVKKSDGI--ASSELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQEN 549
Cdd:PRK03918 368 -----KAKKEELERLKKRLTGLTPEKLEKELEELekAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCG 442
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 550 HDISSRLEQTQLREQLRMQYECSAHL----SIISDLEANVENLENELQAQSKRL-EADIAEVLAAkVEQEKRAIKAEESL 624
Cdd:PRK03918 443 RELTEEHRKELLEEYTAELKRIEKELkeieEKERKLRKELRELEKVLKKESELIkLKELAEQLKE-LEEKLKKYNLEELE 521
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 625 RKARwnnatTAERLQEEFKSLSSQVSSAFSANERL-LVQARKEAAELQLQ--KSQLEELVQKAHEDIASVQEQHRMKIQQ 701
Cdd:PRK03918 522 KKAE-----EYEKLKEKLIKLKGEIKSLKKELEKLeELKKKLAELEKKLDelEEELAELLKELEELGFESVEELEERLKE 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 702 L-------LTLVDFKSnETERLVMELKSKTDEfqnqkrcdeakLNALSEEIDKLKTRIAKLSDERDNLLEKNEKKDMEla 774
Cdd:PRK03918 597 LepfyneyLELKDAEK-ELEREEKELKKLEEE-----------LDKAFEELAETEKRLEELRKELEELEKKYSEEEYE-- 662
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 357146931 775 angEKDMVLQDKTAVIALLNKEVTLLKDQVQTYLEELHTLKHSKNEKDEVIGKLQ 829
Cdd:PRK03918 663 ---ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
310-774 |
6.55e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 53.23 E-value: 6.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 310 EDDVEKLRGEIGTLT-RKLDVSDMELQTLRKQIVKESRRGHDLSKemssLREERDALRRECEGLRGTKKTIHDANGSGKR 388
Cdd:COG4717 48 LERLEKEADELFKPQgRKPELNLKELKELEEELKEAEEKEEEYAE----LQEELEELEEELEELEAELEELREELEKLEK 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 389 LSDGEDPWSQVEELKQELGHEKNLNADLR---LQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETVEDHQEaQYE 465
Cdd:COG4717 124 LLQLLPLYQELEALEAELAELPERLEELEerlEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAE-ELE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 466 HALSNVHTAGHKIDMSETSSYQGKEDelmLDALvkkSDGIASSELEEKIVE--------------LSDEIELYKRDREDL 531
Cdd:COG4717 203 ELQQRLAELEEELEEAQEELEELEEE---LEQL---ENELEAAALEERLKEarlllliaaallalLGLGGSLLSLILTIA 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 532 EMQM---------------EQLALDYEILKQENHDISSRLEQTQLREQL-RMQYECSAHLSIISDLEANVEnlenELQAQ 595
Cdd:COG4717 277 GVLFlvlgllallflllarEKASLGKEAEELQALPALEELEEEELEELLaALGLPPDLSPEELLELLDRIE----ELQEL 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 596 SKRLEADIAEVLAAKVEQEKRAI------KAEESLRkARWNNATTAERLQEEFKSLSSQVSSAFSANERLLVQARKEAAE 669
Cdd:COG4717 353 LREAEELEEELQLEELEQEIAALlaeagvEDEEELR-AALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELE 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 670 LQLQksQLEELVQKAHEDIASVQEQHRMKIQQLLTLvdfksnETERLVMELKsktDEFQNQKrcdeAKLNALSEEIDKLK 749
Cdd:COG4717 432 EELE--ELEEELEELEEELEELREELAELEAELEQL------EEDGELAELL---QELEELK----AELRELAEEWAALK 496
|
490 500
....*....|....*....|....*
gi 357146931 750 TRIAKLSDERDNLLEKNEKKDMELA 774
Cdd:COG4717 497 LALELLEEAREEYREERLPPVLERA 521
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
333-975 |
7.09e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 7.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 333 ELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRgtkKTIHDANGSGKRLSDGEDPW--SQVEELKQELGH-- 408
Cdd:TIGR02169 231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIE---QLLEELNKKIKDLGEEEQLRvkEKIGELEAEIASle 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 409 ----EKNLNA-DLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETVEDHQEaqYEHALSNVH--TAGHKIDMS 481
Cdd:TIGR02169 308 rsiaEKERELeDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEE--LEDLRAELEevDKEFAETRD 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 482 ETSSYQGKEDEL-------------MLDALVKKSDGIASSE-----LEEKIVELSDEIELYKRDREDLEMQMEQLALDYE 543
Cdd:TIGR02169 386 ELKDYREKLEKLkreinelkreldrLQEELQRLSEELADLNaaiagIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 544 ILKQENHDISSRL-----EQTQLREQL-RMQYECSAHLSIISDLEANVENLENELQ------AQSKRLEADIA---EVLA 608
Cdd:TIGR02169 466 KYEQELYDLKEEYdrvekELSKLQRELaEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvAQLGSVGERYAtaiEVAA 545
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 609 AK------VEQEKRAIKAEESLRKARWNNAT----TAERLQEEFKSLSSQ-----------------------------V 649
Cdd:TIGR02169 546 GNrlnnvvVEDDAVAKEAIELLKRRKAGRATflplNKMRDERRDLSILSEdgvigfavdlvefdpkyepafkyvfgdtlV 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 650 SSAFSANERLLVQAR-------------------KEAAELQLQKSQLEELVQKAHEDIASVQEQhRMKIQQLLTLVDFKS 710
Cdd:TIGR02169 626 VEDIEAARRLMGKYRmvtlegelfeksgamtggsRAPRGGILFSRSEPAELQRLRERLEGLKRE-LSSLQSELRRIENRL 704
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 711 NETERLVMELKSKTDEFQNQKRCDEAKLNALSEEIDKLKTRIAKLSDERDNL---LEKNEKK--DMELAANGEKDMV--- 782
Cdd:TIGR02169 705 DELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVkseLKELEARieELEEDLHKLEEALndl 784
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 783 --------LQDKTAVIALLNKEVT---------------------LLKDQVQTYLEELHTLKHSKNEKDEVIGKLQIDIG 833
Cdd:TIGR02169 785 earlshsrIPEIQAELSKLEEEVSriearlreieqklnrltlekeYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKE 864
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 834 SLKLQYDNVKNLLSTKESEKSNLASQVLKLRRAL-ESREGVKENGVTSDAKDNQHSNSKRIKHDTGSTGSSYAPPStdRH 912
Cdd:TIGR02169 865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLrELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK--GE 942
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357146931 913 DANDDCNEHSMRGAGAHADQSTKELDSLKEMNKAMQEELMELHERYSEISLKFAEVEGERQQL 975
Cdd:TIGR02169 943 DEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
306-755 |
7.20e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.40 E-value: 7.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 306 LGGAEDDVEKLRGEIGTLTRKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRgtKKTIHDANGS 385
Cdd:COG1196 332 LEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELA--AQLEELEEAE 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 386 GKRLSDGEDPWSQVEELKQELGHEKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETVEDHQEAQye 465
Cdd:COG1196 410 EALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELA-- 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 466 hALSNVHTAGHKIDMSETSSYQGKEDELMLDALVKKSDGIASSELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEIL 545
Cdd:COG1196 488 -EAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYL 566
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 546 KQENHDISSRLEQTQLREQLRMQYEcsAHLSIISDLEANVENLENELQAQSKRLEADIAE--VLAAKVEQEKRAIKAEES 623
Cdd:COG1196 567 KAAKAGRATFLPLDKIRARAALAAA--LARGAIGAAVDLVASDLREADARYYVLGDTLLGrtLVAARLEAALRRAVTLAG 644
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 624 LRKARWNNATTAERLQEEFKSLSSQVSSAFSANERLLVQARKEAA----ELQLQKSQLEELVQKAHEDIASVQEQHRMKI 699
Cdd:COG1196 645 RLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAeeelELEEALLAEEEEERELAEAEEERLEEELEEE 724
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 357146931 700 QQLLTLVDFKSNETERLVMELKSKTDEFQNQKRcDEAKLNALSEEIDKLKTRIAKL 755
Cdd:COG1196 725 ALEEQLEAEREELLEELLEEEELLEEEALEELP-EPPDLEELERELERLEREIEAL 779
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
511-843 |
8.72e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 53.19 E-value: 8.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 511 EEKIVELSDEIELYKRDREDLEMQMeQLALDYEILKQENHDISSRlEQTQLREQLRMQYECS-----AHLSIISDLEANV 585
Cdd:pfam05483 281 DENLKELIEKKDHLTKELEDIKMSL-QRSMSTQKALEEDLQIATK-TICQLTEEKEAQMEELnkakaAHSFVVTEFEATT 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 586 ENLENELQAQSKRLEADIAEVLAAKVEQEKRAIKAEEsLRKARWNNATTAERLQ-------------EEFKSLSSQVSSA 652
Cdd:pfam05483 359 CSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEE-MTKFKNNKEVELEELKkilaedeklldekKQFEKIAEELKGK 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 653 FSANERLLVQARKEAAELQLQKSQL---EELVQKAHEDIASVQEQHRMKIQQLLTLVDFKS-------NETERLVMELKS 722
Cdd:pfam05483 438 EQELIFLLQAREKEIHDLEIQLTAIktsEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLlenkeltQEASDMTLELKK 517
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 723 KTDEFQNQKRCDEAKLnalsEEIDKLKTRIAKLSDE----RDNLLEKNEKKDMELAANGEKDMVLQ----DKTAVIALLN 794
Cdd:pfam05483 518 HQEDIINCKKQEERML----KQIENLEEKEMNLRDElesvREEFIQKGDEVKCKLDKSEENARSIEyevlKKEKQMKILE 593
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 357146931 795 KEVTLLKDQVQT---YLEELH----TLKHSKNEKDEVIGKLQIDIGSLKLQYDNVK 843
Cdd:pfam05483 594 NKCNNLKKQIENknkNIEELHqenkALKKKGSAENKQLNAYEIKVNKLELELASAK 649
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
508-695 |
1.21e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 52.61 E-value: 1.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 508 SELEEKIVELSDEIEL----------YKRDREDLEMQMEQLA-LDYEILKQENHDISSRLEQtqLREQL-RMQYECSAHL 575
Cdd:COG4913 238 ERAHEALEDAREQIELlepirelaerYAAARERLAELEYLRAaLRLWFAQRRLELLEAELEE--LRAELaRLEAELERLE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 576 SIISDLEANVENLENELQAQS----KRLEADIAEVLAAKVEQEKRAIKAEESLRKARWNNATTAerlqEEFKSLSSQVSS 651
Cdd:COG4913 316 ARLDALREELDELEAQIRGNGgdrlEQLEREIERLERELEERERRRARLEALLAALGLPLPASA----EEFAALRAEAAA 391
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 357146931 652 AFSANERLLVQARKEAAELQLQKSQLEELVQKAHEDIASVQEQH 695
Cdd:COG4913 392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRK 435
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
673-893 |
1.33e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 52.33 E-value: 1.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 673 QKSQLEELvqkaHEDIASVQEQHRMKIQQLLTLvDFKSNETERLVMELKSKTDEFQNQKRCDEAKLNALSEEIDKLKTRI 752
Cdd:TIGR04523 94 NKDKINKL----NSDLSKINSEIKNDKEQKNKL-EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQK 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 753 A-------KLSDERDNLLEKNEKKDMELAANGEKDMVLQDKTAVIALLNKEVTLLKDQVQTYLEELHTLKHSKNEKDEVI 825
Cdd:TIGR04523 169 EelenelnLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEI 248
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 357146931 826 GKLQIDIGSLKLQYDNVKNLLSTKESEK-------SNLASQVLKLRRALESREGVKENGVTSDAKDNQHSNSKRI 893
Cdd:TIGR04523 249 SNTQTQLNQLKDEQNKIKKQLSEKQKELeqnnkkiKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKL 323
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
385-986 |
2.22e-06 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 51.98 E-value: 2.22e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 385 SGKRLSDGE----DPWSQVEELKQELGHE-KNLNADLRL-QLQKMQESNSELLLAVKDLDEVLEQK-NREISILQE-ETV 456
Cdd:TIGR01612 881 SDDKLNDYEkkfnDSKSLINEINKSIEEEyQNINTLKKVdEYIKICENTKESIEKFHNKQNILKEIlNKNIDTIKEsNLI 960
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 457 EDHQEAQYEHALSNVHTAGHKI--DMSeTSSYQGKEDELM-----LDALVKKSDG-----------IASSELEEKIVE-- 516
Cdd:TIGR01612 961 EKSYKDKFDNTLIDKINELDKAfkDAS-LNDYEAKNNELIkyfndLKANLGKNKEnmlyhqfdekeKATNDIEQKIEDan 1039
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 517 ----------------LSDEIE---------LYKRDREDLEMQMEQLALDYEILKQENHD-------ISSRLEQTQLREQ 564
Cdd:TIGR01612 1040 knipnieiaihtsiynIIDEIEkeigknielLNKEILEEAEINITNFNEIKEKLKHYNFDdfgkeenIKYADEINKIKDD 1119
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 565 LR-MQYECSAHLSIISDLEANVENLENELQAQSKRLEaDIAEvlaakveqekRAIKAE--ESLRKARWNNATTAER---L 638
Cdd:TIGR01612 1120 IKnLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLE-DVAD----------KAISNDdpEEIEKKIENIVTKIDKkknI 1188
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 639 QEEFKSLSSQVS------SAFSANERLLVQARKEAAELQLQKSQLEE--------LVQKAHEDIASVQEQHRMKIQQLLT 704
Cdd:TIGR01612 1189 YDEIKKLLNEIAeiekdkTSLEEVKGINLSYGKNLGKLFLEKIDEEKkksehmikAMEAYIEDLDEIKEKSPEIENEMGI 1268
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 705 LVDFKSnETERLVMELKSKTDEFQNQKRCDEAkLNALSEEIDKLKTRIAKLSDERDnlLEKNEKKDMELAA--NGEKDMV 782
Cdd:TIGR01612 1269 EMDIKA-EMETFNISHDDDKDHHIISKKHDEN-ISDIREKSLKIIEDFSEESDIND--IKKELQKNLLDAQkhNSDINLY 1344
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 783 LQDKTAV--IALLNKeVTLLKDQVQTYLEELHtlKHSKNEKDEV------IGKLQIDIgSLKLQYDNVKNLLSTKE---- 850
Cdd:TIGR01612 1345 LNEIANIynILKLNK-IKKIIDEVKEYTKEIE--ENNKNIKDELdkseklIKKIKDDI-NLEECKSKIESTLDDKDidec 1420
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 851 ------------SEKSNLASQvlkLRRALESREGVKENGVTSDAKDNQHSNSKRIKHDTGstgssyappsTDRHDAN-DD 917
Cdd:TIGR01612 1421 ikkikelknhilSEESNIDTY---FKNADENNENVLLLFKNIEMADNKSQHILKIKKDNA----------TNDHDFNiNE 1487
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357146931 918 CNEH--SMRGAGAHADQSTKELDSLKEMNKAMQEELMELHERYSEISLK--FAEVEGERQQLVMTVRTLKNSL 986
Cdd:TIGR01612 1488 LKEHidKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKnkFAKTKKDSEIIIKEIKDAHKKF 1560
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
309-769 |
2.53e-06 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 51.56 E-value: 2.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 309 AEDDVEKLRGEIGTLTRKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRGTKKTIHDANGSgkR 388
Cdd:TIGR04523 305 EQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQS--Y 382
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 389 LSDGEDPWSQVEELKQELGHEKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETVE----------- 457
Cdd:TIGR04523 383 KQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVkeliiknldnt 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 458 -DHQEAQYEHALSNVHTAGHKIDMSETssyQGKEDELMLDALVKKsdgiaSSELEEKIVELSDEIELYKRDREDLEMQME 536
Cdd:TIGR04523 463 rESLETQLKVLSRSINKIKQNLEQKQK---ELKSKEKELKKLNEE-----KKELEEKVKDLTKKISSLKEKIEKLESEKK 534
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 537 QLALDYEILKQENHDISSRLEQTQLREQLRMQYEcsahlsIISDLEANVENLENelqAQSKrleadiAEVLAAKVEQEKR 616
Cdd:TIGR04523 535 EKESKISDLEDELNKDDFELKKENLEKEIDEKNK------EIEELKQTQKSLKK---KQEE------KQELIDQKEKEKK 599
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 617 AIKAEESlrkarwNNATTAERLQEEFKSLSSQvssafsaNERLLVQARKeaaeLQLQKSQLEELVQKAHEDIASVQEQHR 696
Cdd:TIGR04523 600 DLIKEIE------EKEKKISSLEKELEKAKKE-------NEKLSSIIKN----IKSKKNKLKQEVKQIKETIKEIRNKWP 662
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 697 ---MKIQQLLTLVDFKSNETERLVMEL-----KSKTDEFQNQkrcDEAKLNALSEEIDKLKTRIAKLSDERDNLLEKNEK 768
Cdd:TIGR04523 663 eiiKKIKESKTKIDDIIELMKDWLKELslhykKYITRMIRIK---DLPKLEEKYKEIEKELKKLDEFSKELENIIKNFNK 739
|
.
gi 357146931 769 K 769
Cdd:TIGR04523 740 K 740
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
487-838 |
3.75e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.92 E-value: 3.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 487 QGKEDELMLDALvkksdgiasSELEEKIVELSDEIELYKRDREDL---EMQMEQLALDYEILKQENHDIS---SRLEQTQ 560
Cdd:COG4717 62 QGRKPELNLKEL---------KELEEELKEAEEKEEEYAELQEELeelEEELEELEAELEELREELEKLEkllQLLPLYQ 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 561 LREQLRMQY--------ECSAHLSIISDLEANVENLENELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKARWNNA 632
Cdd:COG4717 133 ELEALEAELaelperleELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELE 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 633 TTAERLQEEFKSLSSQVSSAFSANERLLVQARKEAAELQL---------------------------------------- 672
Cdd:COG4717 213 EELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLliaaallallglggsllsliltiagvlflvlgllallfll 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 673 ---QKSQLEELVQKAhEDIASVQEQHRMKIQQLLTLVDFKSNETERLVMELKSKTDEFQNQKRcdeaKLNALSEEIdklk 749
Cdd:COG4717 293 larEKASLGKEAEEL-QALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR----EAEELEEEL---- 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 750 tRIAKLSDERDNLLEKNEKKDME-LAANGEKDMVLQDKTAVIALLNKEVTLLKDQVQTYL---------EELHTLKHSKN 819
Cdd:COG4717 364 -QLEELEQEIAALLAEAGVEDEEeLRAALEQAEEYQELKEELEELEEQLEELLGELEELLealdeeeleEELEELEEELE 442
|
410
....*....|....*....
gi 357146931 820 EKDEVIGKLQIDIGSLKLQ 838
Cdd:COG4717 443 ELEEELEELREELAELEAE 461
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
422-861 |
7.11e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 50.43 E-value: 7.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 422 KMQESNSELLLAVKD---LDEVLEQKNREISILQEETVEDHQEAQ--YEHALSNVHTAGHKIDMSETSSYQGKEDELMLD 496
Cdd:TIGR00606 210 KYLKQYKEKACEIRDqitSKEAQLESSREIVKSYENELDPLKNRLkeIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELE 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 497 ALVKKSDGIASSELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQLREQlRMQYECSAHLS 576
Cdd:TIGR00606 290 LKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQAD-RHQEHIRARDS 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 577 IIsdleanvenLENELQAQSKRLEADiaevlaakvEQEKRAIKAEESLRKARwnnattaerlQEEFKSLSSQVSSAFSAN 656
Cdd:TIGR00606 369 LI---------QSLATRLELDGFERG---------PFSERQIKNFHTLVIER----------QEDEAKTAAQLCADLQSK 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 657 ERLlvqARKEAAELQLQKSQLEELVQKAHEDIASVQEQHRMKIQQLLTLvdfKSNETERLVMELKSKTDEFQNQKRCDEA 736
Cdd:TIGR00606 421 ERL---KQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQL---EGSSDRILELDQELRKAERELSKAEKNS 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 737 KLNALSEEIDKLKTRIAKLSDERDNLLEKNEKKDMELAANGEKDMVLQDKTAVIALLNKEVTLLKDQVQTYL-------- 808
Cdd:TIGR00606 495 LTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLgyfpnkkq 574
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 357146931 809 --EELHTLKHSKNEKDEVIGKLQIDIGSLKLQYDNVKNLLSTKESEKSNLASQVL 861
Cdd:TIGR00606 575 leDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLF 629
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
508-708 |
1.11e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.99 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 508 SELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQLR-EQLRMQYEcsahlSIISDLEANVE 586
Cdd:COG4942 30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAElAELEKEIA-----ELRAELEAQKE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 587 NLENELQAQSKRLEADIAEVL--AAKVEQEKRAIKAEESLRKARWNNATTAERLQEEFKSLSSQVSSAFSANERLLVQAR 664
Cdd:COG4942 105 ELAELLRALYRLGRQPPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELE 184
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 357146931 665 KEAAELQLQKSQLEELVQKAHEDIASVQEQHRMKIQQLLTLVDF 708
Cdd:COG4942 185 EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEAL 228
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
492-762 |
2.86e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.37 E-value: 2.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 492 ELMLDAlvkksdgiasSELEEKIVELSDEIELYKRDREDLEMQMEQLaldyEILKQ--ENHDissrlEQTQLREQLRMQY 569
Cdd:COG4913 215 EYMLEE----------PDTFEAADALVEHFDDLERAHEALEDAREQI----ELLEPirELAE-----RYAAARERLAELE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 570 ECSAHLSI------ISDLEANVENLENELQaqskRLEADIAEVLAAKVEQEKRaikaEESLRKARWNNATTA-ERLQEEf 642
Cdd:COG4913 276 YLRAALRLwfaqrrLELLEAELEELRAELA----RLEAELERLEARLDALREE----LDELEAQIRGNGGDRlEQLERE- 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 643 kslssqvssafsanerlLVQARKEAAELQLQKSQLEELVQKAHEDIASVQEqhrmkiqqlltlvDFKSN--ETERLVMEL 720
Cdd:COG4913 347 -----------------IERLERELEERERRRARLEALLAALGLPLPASAE-------------EFAALraEAAALLEAL 396
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 357146931 721 KSKTDEFQNQKRCDEAKLNALSEEIDKLKTRIAKLSDERDNL 762
Cdd:COG4913 397 EEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNI 438
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
509-694 |
4.70e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.68 E-value: 4.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 509 ELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDissrlEQTQLREQLRMQYECSAHLSI--------ISD 580
Cdd:COG4942 59 ALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA-----QKEELAELLRALYRLGRQPPLalllspedFLD 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 581 LEANVENLE---NELQAQSKRLEADIAEvLAAKVEQEKRAIKAEESLRKARWNNATTAERLQEEFKSLSSQVSSAFSAne 657
Cdd:COG4942 134 AVRRLQYLKylaPARREQAEELRADLAE-LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAE-- 210
|
170 180 190
....*....|....*....|....*....|....*..
gi 357146931 658 rllvqARKEAAELQLQKSQLEELVQKAHEDIASVQEQ 694
Cdd:COG4942 211 -----LAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
326-876 |
4.96e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 47.37 E-value: 4.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 326 KLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEglrgtkKTIHDANGSGKRLSDGEDPWSQVEELKQE 405
Cdd:PRK03918 159 DYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELE------EVLREINEISSELPELREELEKLEKEVKE 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 406 LGHEKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILqEETVEDHQEAQYEhalsnvhtaghkidmSETSS 485
Cdd:PRK03918 233 LEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEEL-EEKVKELKELKEK---------------AEEYI 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 486 YQGKEDELMLDAL--VKKSDGIASSELEEkIVELSDEIELYKRDREDLEMQMEQLALDYEILKqENHDISSRLEQTQLR- 562
Cdd:PRK03918 297 KLSEFYEEYLDELreIEKRLSRLEEEING-IEERIKELEEKEERLEELKKKLKELEKRLEELE-ERHELYEEAKAKKEEl 374
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 563 EQLRMQYECSahlsiisdleaNVENLENELQAQSKR---LEADIAEVLAAKVEQEKRA---IKAEESLRKARWNNATTAE 636
Cdd:PRK03918 375 ERLKKRLTGL-----------TPEKLEKELEELEKAkeeIEEEISKITARIGELKKEIkelKKAIEELKKAKGKCPVCGR 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 637 RLQEEFKslssqvssafsanERLLVQARKEAAELQLQKSQLEELVQKAHEDIASVQE--QHRMKIQQLLTLVDFKSNETE 714
Cdd:PRK03918 444 ELTEEHR-------------KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKvlKKESELIKLKELAEQLKELEE 510
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 715 RL----VMELKSKTDEFQNQKRcdeaKLNALSEEIDKLKTRIAKLSDERDNLLEKNEKKD----------MELAANGEKD 780
Cdd:PRK03918 511 KLkkynLEELEKKAEEYEKLKE----KLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDeleeelaellKELEELGFES 586
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 781 M-VLQDKTAVIALLNKEVTLLKDQVQTYLEELHTLKHSKNEKDEVIGKLQI---DIGSLKLQYDNVKNLLSTKESEksNL 856
Cdd:PRK03918 587 VeELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAEtekRLEELRKELEELEKKYSEEEYE--EL 664
|
570 580
....*....|....*....|.
gi 357146931 857 ASQVLKLRRALES-REGVKEN 876
Cdd:PRK03918 665 REEYLELSRELAGlRAELEEL 685
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
433-984 |
5.26e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 47.34 E-value: 5.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 433 AVKDLDEVLEQKNREiSILQEETVEDHQE--AQYEHALSNVHTAGHKI-DMSETSSYQGKEDELMLDALVKKSDgiASSE 509
Cdd:PRK02224 214 ELAELDEEIERYEEQ-REQARETRDEADEvlEEHEERREELETLEAEIeDLRETIAETEREREELAEEVRDLRE--RLEE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 510 LEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQenhdissRLEQTQLREQlrmqyecsAHLSIISDLEANVENLE 589
Cdd:PRK02224 291 LEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRD-------RLEECRVAAQ--------AHNEEAESLREDADDLE 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 590 N---ELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLR--KARWNNATTA---------------ERLQEEFKSLSSQV 649
Cdd:PRK02224 356 EraeELREEAAELESELEEAREAVEDRREEIEELEEEIEelRERFGDAPVDlgnaedfleelreerDELREREAELEATL 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 650 SSAFSA---NERLLVQAR--------------KEAAELQLQKSQLEELVQKAHEDIASVQEqhrmKIQQLLTLVdfksnE 712
Cdd:PRK02224 436 RTARERveeAEALLEAGKcpecgqpvegsphvETIEEDRERVEELEAELEDLEEEVEEVEE----RLERAEDLV-----E 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 713 TERLVMELKSKTDEFQNQKRCDEAKLNALSEEIDKLKTRIAKLSDERDnlleknEKKDMELAANGEKDMVLQdktaVIAL 792
Cdd:PRK02224 507 AEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAE------EKREAAAEAEEEAEEARE----EVAE 576
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 793 LNKEVTLLKDQVQTyLEELHTLKHSKNEKDEVIGKLQIDIGSLKLQYDNVKNLLSTKESEKSNLASQVLKLRraLESREG 872
Cdd:PRK02224 577 LNSKLAELKERIES-LERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEAR--IEEARE 653
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 873 VKENGVTSDAKDNQHSNSKRIKHDTgstgssyappstdrhdanddcnehsMRGAGAHADQSTKELDSLKEMNKAMQ---E 949
Cdd:PRK02224 654 DKERAEEYLEQVEEKLDELREERDD-------------------------LQAEIGAVENELEELEELRERREALEnrvE 708
|
570 580 590
....*....|....*....|....*....|....*.
gi 357146931 950 ELMELHERYSEISLKFAEVEGE-RQQLVMTVRTLKN 984
Cdd:PRK02224 709 ALEALYDEAEELESMYGDLRAElRQRNVETLERMLN 744
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
398-629 |
6.89e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 6.89e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 398 QVEELKQELGHEKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETVEDHQE-AQYEHALSNVHTAGH 476
Cdd:COG4942 35 EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAElEAQKEELAELLRALY 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 477 KIdmsetssyqGKEDELMLdaLVKKSD---GIASSELEEKIVE-LSDEIELYKRDREDLEMQMEQLALDYEILKQenhdi 552
Cdd:COG4942 115 RL---------GRQPPLAL--LLSPEDfldAVRRLQYLKYLAPaRREQAEELRADLAELAALRAELEAERAELEA----- 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 553 ssrLEQTQLREQLRMQYECSAHLSIISDLEANVENLENE---LQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKARW 629
Cdd:COG4942 179 ---LLAELEEERAALEALKAERQKLLARLEKELAELAAElaeLQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
398-805 |
7.65e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 46.68 E-value: 7.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 398 QVEELKQELGHEKNLNADLRLQLQKM--QESNSELLLAVKDLDEVLEQKNREI-SILQEETVEDHQEAQYEHALSNVHTA 474
Cdd:COG4717 96 ELEELEEELEELEAELEELREELEKLekLLQLLPLYQELEALEAELAELPERLeELEERLEELRELEEELEELEAELAEL 175
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 475 GHKIDMSETSSYQGKEDELmldalvkksdgiasSELEEKIVELSDEIELYKRDREDLEMQMEQLaldyeilKQENHDISS 554
Cdd:COG4717 176 QEELEELLEQLSLATEEEL--------------QDLAEELEELQQRLAELEEELEEAQEELEEL-------EEELEQLEN 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 555 RLEQTQLREQLRMQYECSAHLSIISDLEANVENLENELQAQSKRLeADIAEVLAAKVEQEKRAIKAEESLRKARWNNATT 634
Cdd:COG4717 235 ELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVL-FLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 635 AERLQEEFKSLSSQVSSAFSANERLLVQARKEAAELQLQKSQLEELVQKAHediasvQEQHRMKIQQLLTLVDFKSNET- 713
Cdd:COG4717 314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ------LEELEQEIAALLAEAGVEDEEEl 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 714 -----------------ERLVMELKSKTDEFQNQKRCD------------EAKLNALSEEIDKLKTRIAKL--------- 755
Cdd:COG4717 388 raaleqaeeyqelkeelEELEEQLEELLGELEELLEALdeeeleeeleelEEELEELEEELEELREELAELeaeleqlee 467
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 357146931 756 SDERDNLLEKNEKKDMELAANGEKDMVLQdktAVIALLNKEVTLLKDQVQ 805
Cdd:COG4717 468 DGELAELLQELEELKAELRELAEEWAALK---LALELLEEAREEYREERL 514
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
633-875 |
7.77e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.83 E-value: 7.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 633 TTAERLQEEFKSLSSqvssafsanerllvqARKEAAELQLQKSQLEELVQkAHEDIASVQEQHRmKIQQLLTLVDFKSNE 712
Cdd:COG4913 225 EAADALVEHFDDLER---------------AHEALEDAREQIELLEPIRE-LAERYAAARERLA-ELEYLRAALRLWFAQ 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 713 TERlvmelksktDEFQNQKRCDEAKLNALSEEIDKLKTRIAKLSDERDNLLEknekkdmELAANGEKDmvLQDKTAVIAL 792
Cdd:COG4913 288 RRL---------ELLEAELEELRAELARLEAELERLEARLDALREELDELEA-------QIRGNGGDR--LEQLEREIER 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 793 LNKEVTLLKDQVQTYLEELHTLKHS------------------KNEKDEVIGKLQIDIGSLKLQYDNVKNLLSTKESE-- 852
Cdd:COG4913 350 LERELEERERRRARLEALLAALGLPlpasaeefaalraeaaalLEALEEELEALEEALAEAEAALRDLRRELRELEAEia 429
|
250 260
....*....|....*....|....*...
gi 357146931 853 -----KSNLASQVLKLRRALESREGVKE 875
Cdd:COG4913 430 slerrKSNIPARLLALRDALAEALGLDE 457
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
604-815 |
7.92e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 7.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 604 AEVLAAKVEQEKRAIKAE-ESLRKARWNNATTAERLQEEFKSLSSQVSSAF---SANERLLVQARKEAAELQLQKSQLEE 679
Cdd:COG4942 18 QADAAAEAEAELEQLQQEiAELEKELAALKKEEKALLKQLAALERRIAALArriRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 680 LVQKAHEDIAS-VQEQHRMKIQQLLTLV----DFksNETERLVMELKSKTDEFQNQkrcdEAKLNALSEEIDKLKTRIAK 754
Cdd:COG4942 98 ELEAQKEELAElLRALYRLGRQPPLALLlspeDF--LDAVRRLQYLKYLAPARREQ----AEELRADLAELAALRAELEA 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 357146931 755 LSDERDNLLEKNEKKDMELAANgekdmvLQDKTAVIALLNKEVTLLKDQVQTYLEELHTLK 815
Cdd:COG4942 172 ERAELEALLAELEEERAALEAL------KAERQKLLARLEKELAELAAELAELQQEAEELE 226
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
649-869 |
9.51e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 9.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 649 VSSAFSANERLLVQARKEAAELQLQKSQLEELVQKAHEDIASVQEQhrmkiqqlLTLVDFKSNETERLVMELKSKTDEFq 728
Cdd:COG4942 11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ--------LAALERRIAALARRIRALEQELAAL- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 729 nqkrcdEAKLNALSEEIDKLKTRIAKLSDERDNLL---EKNEKKD-MELAANGEKDMVLQDKTAVIALLNKEVTLLKDQV 804
Cdd:COG4942 82 ------EAELAELEKEIAELRAELEAQKEELAELLralYRLGRQPpLALLLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 357146931 805 QTYLEELHTLKHS----KNEKDEVIGKLQIDIGSLKLQYDNVKNLLSTKESEKSNLASQVLKLRRALES 869
Cdd:COG4942 156 RADLAELAALRAEleaeRAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
509-974 |
1.96e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 45.42 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 509 ELEEKIVELSDEIELYKRDREDLEMQMEQLAL---DYEILKQENHDISSRLEQTQ--LREQLRmqyECSAHLSIISDLEA 583
Cdd:PRK02224 210 GLESELAELDEEIERYEEQREQARETRDEADEvleEHEERREELETLEAEIEDLRetIAETER---EREELAEEVRDLRE 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 584 NVENLE---NELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKARwnnaTTAERLQEEFKSLSSQVSSAFSANERLl 660
Cdd:PRK02224 287 RLEELEeerDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECR----VAAQAHNEEAESLREDADDLEERAEEL- 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 661 vqaRKEAAELQLQKSQLEELVQKAHEDIASVQEQhrmkIQQLLTLVDFKSNETERLvmelksktdefqnqkrcdEAKLNA 740
Cdd:PRK02224 362 ---REEAAELESELEEAREAVEDRREEIEELEEE----IEELRERFGDAPVDLGNA------------------EDFLEE 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 741 LSEEIDKLKTRIAKLSDERDNLLEKNEKKDMELAA-----------NGEKDMVLQDKTAVIALLNKEVTLLKDQVQTYLE 809
Cdd:PRK02224 417 LREERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpveGSPHVETIEEDRERVEELEAELEDLEEEVEEVEE 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 810 ELHTLKHSKNEKDEvigklqidIGSLKLQYDNVKNLLSTKES---EKSNLASQVLKLRRALESREGVKEngvtsDAKDNQ 886
Cdd:PRK02224 497 RLERAEDLVEAEDR--------IERLEERREDLEELIAERREtieEKRERAEELRERAAELEAEAEEKR-----EAAAEA 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 887 HSNSKRIKHDTGSTGSSYAPpSTDRHDANDDCNEHSMRGAGAHADQST--KELDSLKEMNKAMQEELMELHERYSEISLK 964
Cdd:PRK02224 564 EEEAEEAREEVAELNSKLAE-LKERIESLERIRTLLAAIADAEDEIERlrEKREALAELNDERRERLAEKRERKRELEAE 642
|
490
....*....|..
gi 357146931 965 F--AEVEGERQQ 974
Cdd:PRK02224 643 FdeARIEEARED 654
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
433-892 |
2.15e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.52 E-value: 2.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 433 AVKDLDEVleQKNREISILQEETVEDHQEAQYEHALSNVHTAGHKIDMSETSSyqgKEDELMLDALVKKSDGIASSELEE 512
Cdd:PTZ00121 1228 AVKKAEEA--KKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEAR---KADELKKAEEKKKADEAKKAEEKK 1302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 513 KIVELSDEIElYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQLREQLRMQYECSAHLSIISDLEANVENLENEL 592
Cdd:PTZ00121 1303 KADEAKKKAE-EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD 1381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 593 QAQSKRLEADIAEVLAAKVEQEKRaiKAEESLRKArwnnatTAERLQEEFKSLSSQVSSAFSANERllVQARKEAAELQL 672
Cdd:PTZ00121 1382 AAKKKAEEKKKADEAKKKAEEDKK--KADELKKAA------AAKKKADEAKKKAEEKKKADEAKKK--AEEAKKADEAKK 1451
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 673 ---QKSQLEELVQKAHEdiASVQEQHRMKIQQlltlvDFKSNETERLVMELKSKTDEF----QNQKRCDEAKLNALSEEI 745
Cdd:PTZ00121 1452 kaeEAKKAEEAKKKAEE--AKKADEAKKKAEE-----AKKADEAKKKAEEAKKKADEAkkaaEAKKKADEAKKAEEAKKA 1524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 746 DKL-KTRIAKLSDERDNLLEK---------------NEKKDMELAANGEKDMVLQDKTAVIALLNKEVTLLKDQVQTYLE 809
Cdd:PTZ00121 1525 DEAkKAEEAKKADEAKKAEEKkkadelkkaeelkkaEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEE 1604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 810 ELHTLKHSKNEKDEVIGKLQIDIGS---LKLQYDNVKNLLSTKESEKSNLASQVLKLRRALESREGVKENGVTSDAKDNQ 886
Cdd:PTZ00121 1605 KKMKAEEAKKAEEAKIKAEELKKAEeekKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAE 1684
|
....*.
gi 357146931 887 HSNSKR 892
Cdd:PTZ00121 1685 EDEKKA 1690
|
|
| PRK00409 |
PRK00409 |
recombination and DNA strand exchange inhibitor protein; Reviewed |
656-866 |
2.34e-04 |
|
recombination and DNA strand exchange inhibitor protein; Reviewed
Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 45.20 E-value: 2.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 656 NERLLVQARKEAAElqlQKSQLEELvqkahedIASVQEQhRMKIQQLLTLVDFKSNETERLVMELKSKTDEFQNQKRcde 735
Cdd:PRK00409 500 PENIIEEAKKLIGE---DKEKLNEL-------IASLEEL-ERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEED--- 565
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 736 aklNALSEEIDKLKTRIAKLSDERDNLL-EKNEKKDMELAANGEKDmvLQDKTAVIALLNKEVT---LLKDQVQTYLEE- 810
Cdd:PRK00409 566 ---KLLEEAEKEAQQAIKEAKKEADEIIkELRQLQKGGYASVKAHE--LIEARKRLNKANEKKEkkkKKQKEKQEELKVg 640
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 357146931 811 ----LHTLKH-----SKNEKDEVIgkLQIDIGSLKLQYDNVKNLLSTKESEKSNLASQVLKLRRA 866
Cdd:PRK00409 641 devkYLSLGQkgevlSIPDDKEAI--VQAGIMKMKVPLSDLEKIQKPKKKKKKKPKTVKPKPRTV 703
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
336-872 |
2.37e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 45.12 E-value: 2.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 336 TLRKQIVKESRRGHDLSKEMSSLR----EERDALRRECEGLRGTKKTIHDANgsgKRLSDGEDPWSQVEELKQELGHEKn 411
Cdd:pfam05557 38 ALKRQLDRESDRNQELQKRIRLLEkreaEAEEALREQAELNRLKKKYLEALN---KKLNEKESQLADAREVISCLKNEL- 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 412 lnADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILqEETVEDHQEAQYEHALSN--VHTAGHKIDMSETSSyqgk 489
Cdd:pfam05557 114 --SELRRQIQRAELELQSTNSELEELQERLDLLKAKASEA-EQLRQNLEKQQSSLAEAEqrIKELEFEIQSQEQDS---- 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 490 edelmldALVKKSdgiaSSELEeKIVELSDEIElykRDREDLEmQMEQLALDYEILKQENHDISSRLEQTQ-LREQLrmq 568
Cdd:pfam05557 187 -------EIVKNS----KSELA-RIPELEKELE---RLREHNK-HLNENIENKLLLKEEVEDLKRKLEREEkYREEA--- 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 569 yecsahlsiiSDLEANVENLENELQ-----AQSKRLEADIAEVLAAKVEQekraIKAEESLRKARWNNATTAER------ 637
Cdd:pfam05557 248 ----------ATLELEKEKLEQELQswvklAQDTGLNLRSPEDLSRRIEQ----LQQREIVLKEENSSLTSSARqlekar 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 638 --LQEEFKSLSSQVSSAFSANERLLVQARK-------EAAELQLQKSQLEELVQKAHEDIASVQEQHRMK-IQQLLTLVD 707
Cdd:pfam05557 314 reLEQELAQYLKKIEDLNKKLKRHKALVRRlqrrvllLTKERDGYRAILESYDKELTMSNYSPQLLERIEeAEDMTQKMQ 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 708 FKSNETERLVMELKSKTDEFQNQKRCDEAKLNAL------------SEEIDKLKTRIAKLSDERDNLLEKNEKKDMELAA 775
Cdd:pfam05557 394 AHNEEMEAQLSVAEEELGGYKQQAQTLERELQALrqqesladpsysKEEVDSLRRKLETLELERQRLREQKNELEMELER 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 776 NGEKDMVLQDKTAVIallnkevtllkdqvqtYLEELHTLKHSKNEKDEViGKLQIDIGSLK----LQYDNVKNLLSTKES 851
Cdd:pfam05557 474 RCLQGDYDPKKTKVL----------------HLSMNPAAEAYQQRKNQL-EKLQAEIERLKrllkKLEDDLEQVLRLPET 536
|
570 580
....*....|....*....|.
gi 357146931 852 EKSNLASQVLKLRRALESREG 872
Cdd:pfam05557 537 TSTMNFKEVLDLRKELESAEL 557
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
309-784 |
2.57e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 2.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 309 AEDDVEKLRGEIGTLT-----RKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRGT-----KKT 378
Cdd:COG4913 267 ARERLAELEYLRAALRlwfaqRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDrleqlERE 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 379 IHDANgsgKRLSDGEDPWSQVEELKQELGHEKNLNADlrlQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETVED 458
Cdd:COG4913 347 IERLE---RELEERERRRARLEALLAALGLPLPASAE---EFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 459 HQEAQYEhaLSNVHTAGHKIDmsetssyqgKEDELMLDALVKKSdGIASSELeeKIV-ELsdeIELYKRDrEDLEMQMEQ 537
Cdd:COG4913 421 LRELEAE--IASLERRKSNIP---------ARLLALRDALAEAL-GLDEAEL--PFVgEL---IEVRPEE-ERWRGAIER 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 538 L----ALDyeILKQENH--DISSRLEQTQLREQLRMQ-YECSAHLSIISDLEAN--VENLENELQAQSKRLEADIAEVLA 608
Cdd:COG4913 483 VlggfALT--LLVPPEHyaAALRWVNRLHLRGRLVYErVRTGLPDPERPRLDPDslAGKLDFKPHPFRAWLEAELGRRFD 560
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 609 -AKVE------QEKRAI--------------KAEESLRKARW----NNATTAERLQEEFKSLSSQVSSAfsanERLLVQA 663
Cdd:COG4913 561 yVCVDspeelrRHPRAItragqvkgngtrheKDDRRRIRSRYvlgfDNRAKLAALEAELAELEEELAEA----EERLEAL 636
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 664 RKEAAELQLQKSQLEELVQKAHEDI--ASVQEQHRmKIQQLLTLVDFKSNETERLVMELKSKtdefqnqkrcdEAKLNAL 741
Cdd:COG4913 637 EAELDALQERREALQRLAEYSWDEIdvASAEREIA-ELEAELERLDASSDDLAALEEQLEEL-----------EAELEEL 704
|
490 500 510 520
....*....|....*....|....*....|....*....|...
gi 357146931 742 SEEIDKLKTRIAKLSDERDNLLEKNEKKDMELAANGEKDMVLQ 784
Cdd:COG4913 705 EEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLEL 747
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
509-626 |
2.87e-04 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 44.69 E-value: 2.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 509 ELEEKIVELSDEIELYKRDR--------EDLEMQMEQLALDYEILKQENHDISSRLEQTQ-LREQLRMQYEcsahlsIIS 579
Cdd:COG0542 415 ELERRLEQLEIEKEALKKEQdeasferlAELRDELAELEEELEALKARWEAEKELIEEIQeLKEELEQRYG------KIP 488
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 357146931 580 DLEANVENLENELQAQSKRL-----EADIAEVLAAK--------VEQEK-RAIKAEESLRK 626
Cdd:COG0542 489 ELEKELAELEEELAELAPLLreevtEEDIAEVVSRWtgipvgklLEGEReKLLNLEEELHE 549
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
435-726 |
3.43e-04 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 44.53 E-value: 3.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 435 KDLDEVLEqKNREISILQ-EETVEDHQEAQYEHALSNVHTAGHKID-MSETSSYQGKEDELM-------LDALVKKSDGI 505
Cdd:PRK05771 16 SYKDEVLE-ALHELGVVHiEDLKEELSNERLRKLRSLLTKLSEALDkLRSYLPKLNPLREEKkkvsvksLEELIKDVEEE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 506 AS------SELEEKIVELSDEIELYKRDREDLEmQMEQLALDYEILKqENHDISSRLEQTQlREQLRmqyecsaHLSIIS 579
Cdd:PRK05771 95 LEkiekeiKELEEEISELENEIKELEQEIERLE-PWGNFDLDLSLLL-GFKYVSVFVGTVP-EDKLE-------ELKLES 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 580 DLEaNVENLENELQ------AQSKRLEADIAEVLaAKVEQEKRAIKAEESlrkarwnnattaerLQEEFKSLSSQVSSaf 653
Cdd:PRK05771 165 DVE-NVEYISTDKGyvyvvvVVLKELSDEVEEEL-KKLGFERLELEEEGT--------------PSELIREIKEELEE-- 226
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357146931 654 sanerllVQARKEAAelqlqKSQLEELVQKAHEDIASVQEqhrmkiqqLLtlvdfkSNETERLVMELKSKTDE 726
Cdd:PRK05771 227 -------IEKERESL-----LEELKELAKKYLEELLALYE--------YL------EIELERAEALSKFLKTD 273
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
325-891 |
3.73e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 44.75 E-value: 3.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 325 RKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRGT---KKTIHDANGSGKRLSDGEDPWSQVEE 401
Cdd:PTZ00121 1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdeaKKKAEEDKKKADELKKAAAAKKKADE 1422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 402 LKQELGHEKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETVEDHQEAQYEHALSNVHTAGHKID-M 480
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADeA 1502
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 481 SETSSYQGKEDELMLDALVKKSDGIASSELEEKIVELSDEIELYKRDredlemqmeqlaldyEILKQENhdiSSRLEQTQ 560
Cdd:PTZ00121 1503 KKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKAD---------------ELKKAEE---LKKAEEKK 1564
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 561 LREQLRMQYEcsahlsiisDLEANVENLENELQAQSKRLEAdiaevlAAKVEQEKRAIKAEEsLRKARWNNATTAE-RLQ 639
Cdd:PTZ00121 1565 KAEEAKKAEE---------DKNMALRKAEEAKKAEEARIEE------VMKLYEEEKKMKAEE-AKKAEEAKIKAEElKKA 1628
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 640 EEFKSLSSQVSSAFSANERLLVQARKEAAELQLQKSQL---EELVQKAHEDIASVQEQHRMKIQQLLtlvdfKSNETERL 716
Cdd:PTZ00121 1629 EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEakkAEEDKKKAEEAKKAEEDEKKAAEALK-----KEAEEAKK 1703
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 717 VMELKSKTDEfqNQKRCDEAKlnaLSEEIDKLKTRIAKLSDERDNLLEKNEKKDmelaaNGEKDMVLQDKTAViallNKE 796
Cdd:PTZ00121 1704 AEELKKKEAE--EKKKAEELK---KAEEENKIKAEEAKKEAEEDKKKAEEAKKD-----EEEKKKIAHLKKEE----EKK 1769
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 797 VTLLKDQVQTYLEElhTLKHSKNEKDEVIGKLQIDI--GSLKLQYDNVKNLL---STKESEKSNLASQVLKLRRALESRE 871
Cdd:PTZ00121 1770 AEEIRKEKEAVIEE--ELDEEDEKRRMEVDKKIKDIfdNFANIIEGGKEGNLvinDSKEMEDSAIKEVADSKNMQLEEAD 1847
|
570 580
....*....|....*....|
gi 357146931 872 GVKENGVTSDAKDNQHSNSK 891
Cdd:PTZ00121 1848 AFEKHKFNKNNENGEDGNKE 1867
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
510-694 |
3.93e-04 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.24 E-value: 3.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 510 LEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQLREQL-RMQYECSAHLSIISDLEANVENL 588
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQLsELESQLAEARAELAEAEARLAAL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 589 ENELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKARW-NNATTAERLQEEFKSLSSQVSsafSANERLLVQARKEA 667
Cdd:COG3206 246 RAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYtPNHPDVIALRAQIAALRAQLQ---QEAQRILASLEAEL 322
|
170 180
....*....|....*....|....*..
gi 357146931 668 AELQLQKSQLEELVQKAHEDIASVQEQ 694
Cdd:COG3206 323 EALQAREASLQAQLAQLEARLAELPEL 349
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
320-729 |
3.97e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 44.65 E-value: 3.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 320 IGTLTRKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRGTKKTIHDANGSGKrlSDGEDPWSQV 399
Cdd:TIGR00606 697 ISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLK--NDIEEQETLL 774
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 400 EELKQELGHEKNLNADL----RLQLQKMQESNSELLLAVK----DLDEVLEQKNREISILQEETVEDHQEAQYEHALSNV 471
Cdd:TIGR00606 775 GTIMPEEESAKVCLTDVtimeRFQMELKDVERKIAQQAAKlqgsDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQD 854
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 472 HTaghkidmSETSSYQGKEDELMLDALVKKSDGIASSELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHD 551
Cdd:TIGR00606 855 QQ-------EQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEE 927
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 552 ISSRLEQTQLREQLRMQYECSAHLSIISDLEANVENLENELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKARWNN 631
Cdd:TIGR00606 928 LISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI 1007
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 632 ATTAER---LQEEFKSLssQVSSAFSANERLLVQARKEAAELQLqkSQLEELVQKAHEDIASVQEQHRMKIQQLltlvdf 708
Cdd:TIGR00606 1008 DTQKIQerwLQDNLTLR--KRENELKEVEEELKQHLKEMGQMQV--LQMKQEHQKLEENIDLIKRNHVLALGRQ------ 1077
|
410 420
....*....|....*....|.
gi 357146931 709 KSNETERLVMELKSKTDEFQN 729
Cdd:TIGR00606 1078 KGYEKEIKHFKKELREPQFRD 1098
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
509-784 |
5.22e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 44.01 E-value: 5.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 509 ELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQLREQLRMQyecsahlsIISDLEANVENL 588
Cdd:pfam01576 633 EKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQ--------QVEEMKTQLEEL 704
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 589 ENELQAQSK---RLEADIAEV-------LAAKVEQ--EK--------RAIKAE-ESLRKARWNNATTAERLQEEFKSLSS 647
Cdd:pfam01576 705 EDELQATEDaklRLEVNMQALkaqferdLQARDEQgeEKrrqlvkqvRELEAElEDERKQRAQAVAAKKKLELDLKELEA 784
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 648 QVSSAFSANERLLVQARKEAAELQLQKSQLEELVQKAHEDIASVQEQHRMKIQQLLTLVDFKSN--ETERLVMELKSKTD 725
Cdd:pfam01576 785 QIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDlaASERARRQAQQERD 864
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 357146931 726 EFQNQKRCDEAKLNALSEEIDKLKTRIAKLSDERDnllekNEKKDMELAANGEKDMVLQ 784
Cdd:pfam01576 865 ELADEIASGASGKSALQDEKRRLEARIAQLEEELE-----EEQSNTELLNDRLRKSTLQ 918
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
324-725 |
5.42e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.14 E-value: 5.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 324 TRKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRecegLRGTKKTIHDANGSGKRLsdgedpwsqvEELK 403
Cdd:COG4913 609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQR----LAEYSWDEIDVASAEREI----------AELE 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 404 QELGHEKNLNADLRlQLQKMQEsnsELLLAVKDLDEVLEQKNREISILQEEtVEDHQEAQyEHALSNVHTAGHKIDMSET 483
Cdd:COG4913 675 AELERLDASSDDLA-ALEEQLE---ELEAELEELEEELDELKGEIGRLEKE-LEQAEEEL-DELQDRLEAAEDLARLELR 748
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 484 SSYQGKEDELMLDALVKKsdgiASSELEEKIVELSDEIElykRDREDLEMQMEQLALDYEILKQE-NHDISSRLEQTQLR 562
Cdd:COG4913 749 ALLEERFAAALGDAVERE----LRENLEERIDALRARLN---RAEEELERAMRAFNREWPAETADlDADLESLPEYLALL 821
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 563 EQLRmqyecsahlsiISDLEANVENLENELQAQSKRleaDIAEvLAAKVEQEKRAIKaeeslrkarwnnattaERLQEEF 642
Cdd:COG4913 822 DRLE-----------EDGLPEYEERFKELLNENSIE---FVAD-LLSKLRRAIREIK----------------ERIDPLN 870
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 643 KSLSsqvSSAFSANERL-LVQARKEAAELQLQKSQLEELVQKAHEDIASVQEQHRMKIQQLLTLvdFKSNETERLVMELK 721
Cdd:COG4913 871 DSLK---RIPFGPGRYLrLEARPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRLIER--LRSEEEESDRRWRA 945
|
....
gi 357146931 722 SKTD 725
Cdd:COG4913 946 RVLD 949
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
660-828 |
5.81e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.60 E-value: 5.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 660 LVQARKEAAELQLQKSQLEELVQKAHEDIASVQEQHRmKIQQLLTLVDFKSNETERLVMELKSKTDEFQNQKrcdeaKLN 739
Cdd:COG1579 19 LDRLEHRLKELPAELAELEDELAALEARLEAAKTELE-DLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNK-----EYE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 740 ALSEEIDKLKTRIAKLSDErdnLLEKNEKKDmelaangEKDMVLQDKTAVIALLNKEVTLLKDQVQTYLEELHT-LKHSK 818
Cdd:COG1579 93 ALQKEIESLKRRISDLEDE---ILELMERIE-------ELEEELAELEAELAELEAELEEKKAELDEELAELEAeLEELE 162
|
170
....*....|
gi 357146931 819 NEKDEVIGKL 828
Cdd:COG1579 163 AEREELAAKI 172
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
333-703 |
6.44e-04 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 43.52 E-value: 6.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 333 ELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRGTKKTIHDANGSG----KRLSDGEdpwSQVEELKQELGH 408
Cdd:pfam05622 1 DLSEAQEEKDELAQRCHELDQQVSLLQEEKNSLQQENKKLQERLDQLESGDDSGtpggKKYLLLQ---KQLEQLQEENFR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 409 EKNLNADLRL-------QLQKMQESNSEL------LLAVKDLDEVLEQKNREISILqEETVEdhqeaQYEHALSNVHTAG 475
Cdd:pfam05622 78 LETARDDYRIkceelekEVLELQHRNEELtslaeeAQALKDEMDILRESSDKVKKL-EATVE-----TYKKKLEDLGDLR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 476 HKIDMSETSSYQGKEDELMLDALVKKSDGiASSELE---EKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDI 552
Cdd:pfam05622 152 RQVKLLEERNAEYMQRTLQLEEELKKANA-LRGQLEtykRQVQELHGKLSEESKKADKLEFEYKKLEEKLEALQKEKERL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 553 SSrlEQTQLRE---QLR----MQYECSAHLSIISDLEANVENLENE------------LQAQSKRL--------EADIAE 605
Cdd:pfam05622 231 II--ERDTLREtneELRcaqlQQAELSQADALLSPSSDPGDNLAAEimpaeireklirLQHENKMLrlgqegsyRERLTE 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 606 VLAAKVEQEKRAIKAEESLRKARWNNATTAERLQEEFKSLSSQVSSAFSAN------ERLLVQARKEAAELQLQKSQLEE 679
Cdd:pfam05622 309 LQQLLEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSllkqklEEHLEKLHEAQSELQKKKEQIEE 388
|
410 420
....*....|....*....|....*...
gi 357146931 680 LVQKA----HEDIASVQEQHRMKIQQLL 703
Cdd:pfam05622 389 LEPKQdsnlAQKIDELQEALRKKDEDMK 416
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
333-682 |
6.95e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.79 E-value: 6.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 333 ELQTLRKQIVKESRRGHDLSKEMSSL--REE---------RDALRRECEGLRGTKKTIH---DANGSGKRLSDGEDpwsQ 398
Cdd:COG3096 293 ELFGARRQLAEEQYRLVEMARELEELsaRESdleqdyqaaSDHLNLVQTALRQQEKIERyqeDLEELTERLEEQEE---V 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 399 VEELKQELgheknlnADLRLQLQKMQESNSELLLAVKDLDEVL-EQKNR------------------EISILQEETVEDH 459
Cdd:COG3096 370 VEEAAEQL-------AEAEARLEAAEEEVDSLKSQLADYQQALdVQQTRaiqyqqavqalekaralcGLPDLTPENAEDY 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 460 QE---AQYEHALSNVHTAGHKIDMSETSSYQGKEdelMLDALVKKSDGIASSELEEKIVELSdeielykRDREDLEMQME 536
Cdd:COG3096 443 LAafrAKEQQATEEVLELEQKLSVADAARRQFEK---AYELVCKIAGEVERSQAWQTARELL-------RRYRSQQALAQ 512
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 537 QLaldyEILKQENHDISSRLEQTQLREQLRMQYECSAHLSIisDLEANVENLENELQAQSKRLEADIAEVLA--AKVEQE 614
Cdd:COG3096 513 RL----QQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQL--DAAEELEELLAELEAQLEELEEQAAEAVEqrSELRQQ 586
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 615 KRAIKAE-ESLRK--ARWNNATTA-ERLQEE----FKSlSSQVSSAFSA---NERLLVQARKEAAELQLQ-KSQLEELVQ 682
Cdd:COG3096 587 LEQLRARiKELAAraPAWLAAQDAlERLREQsgeaLAD-SQEVTAAMQQlleREREATVERDELAARKQAlESQIERLSQ 665
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
370-704 |
7.29e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 43.50 E-value: 7.29e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 370 EGLRGTKKTIHDANGSGKRLsdgeDPWSQV--------EELKQELGHEKNLNADLRLQL------QKMQESNSELLLAVK 435
Cdd:PRK10929 48 EALQSALNWLEERKGSLERA----KQYQQVidnfpklsAELRQQLNNERDEPRSVPPNMstdaleQEILQVSSQLLEKSR 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 436 DLDEvlEQ-KNREIS-----ILQEETVEDHQEAQYE---HALSNVHT----AGHKIDMSETSSYQGKEDELMLDALvkks 502
Cdd:PRK10929 124 QAQQ--EQdRAREISdslsqLPQQQTEARRQLNEIErrlQTLGTPNTplaqAQLTALQAESAALKALVDELELAQL---- 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 503 dgiaSSELEEKIVELSdeIELYKRDREDLEMQMEQLALDYEILKQENHDISsrLEQT-QLREQlrmqyecSAHL--SIIS 579
Cdd:PRK10929 198 ----SANNRQELARLR--SELAKKRSQQLDAYLQALRNQLNSQRQREAERA--LESTeLLAEQ-------SGDLpkSIVA 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 580 DLEANVEnLENELQAQSKRLEAdIAE---VLAAKVEQEKRAIKAeesLR-KARWNNATTAerLQEefkSLSSQVSsafsa 655
Cdd:PRK10929 263 QFKINRE-LSQALNQQAQRMDL-IASqqrQAASQTLQVRQALNT---LReQSQWLGVSNA--LGE---ALRAQVA----- 327
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 357146931 656 neRL-----LVQARKEAAELQLQKSQLEELVQKAHEDIASVQ--------EQHRMKIQQLLT 704
Cdd:PRK10929 328 --RLpempkPQQLDTEMAQLRVQRLRYEDLLNKQPQLRQIRQadgqpltaEQNRILDAQLRT 387
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
333-679 |
9.02e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 43.41 E-value: 9.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 333 ELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECE-----------GLRGTKKtIHDANGSGKRLSDGEDPWSQVEE 401
Cdd:PRK04863 294 ELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQaasdhlnlvqtALRQQEK-IERYQADLEELEERLEEQNEVVE 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 402 LKQELgheknlNADLRLQLQKMQESNSELLLAVKDLDEVLE-------QKNREISILQE------------ETVEDHQE- 461
Cdd:PRK04863 373 EADEQ------QEENEARAEAAEEEVDELKSQLADYQQALDvqqtraiQYQQAVQALERakqlcglpdltaDNAEDWLEe 446
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 462 --AQYEHALSNVHTAGHKIDMSETSSYQgkeDELMLDALVKKSDGIASSELEEKIVELSdeielykRDREDLEMQMEQLa 539
Cdd:PRK04863 447 fqAKEQEATEELLSLEQKLSVAQAAHSQ---FEQAYQLVRKIAGEVSRSEAWDVARELL-------RRLREQRHLAEQL- 515
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 540 ldyEILKQENHDISSRLEQTQLREQLRMQYECSAHLSIisDLEANVENLENELQAQSKRLEADIAEVLAAK--VEQEKRA 617
Cdd:PRK04863 516 ---QQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNL--DDEDELEQLQEELEARLESLSESVSEARERRmaLRQQLEQ 590
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 618 IKAEESLRKAR---WNNATTA-ERLQE----EFKSlSSQVSSAFSANERLLVQARKEAAELQLQKSQLEE 679
Cdd:PRK04863 591 LQARIQRLAARapaWLAAQDAlARLREqsgeEFED-SQDVTEYMQQLLERERELTVERDELAARKQALDE 659
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
397-668 |
9.71e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.51 E-value: 9.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 397 SQVEELKQELGHEKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEEtvEDHQEAQYEHALSnvhtagh 476
Cdd:COG3883 23 KELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAE--IEERREELGERAR------- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 477 kidmsetSSYQGKEDELMLDALVKK---SDGIASSELEEKIVEL-SDEIELYKRDREDLEMQMEQLaldyeilkqenhdi 552
Cdd:COG3883 94 -------ALYRSGGSVSYLDVLLGSesfSDFLDRLSALSKIADAdADLLEELKADKAELEAKKAEL-------------- 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 553 ssrleQTQLREQLRMQYECSAHLSIISDLEANVENLENELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKARWNNA 632
Cdd:COG3883 153 -----EAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAA 227
|
250 260 270
....*....|....*....|....*....|....*.
gi 357146931 633 TTAERLQEEFKSLSSQVSSAFSANERLLVQARKEAA 668
Cdd:COG3883 228 AAAAAAAAAAAAAAAAASAAGAGAAGAAGAAAGSAG 263
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
495-844 |
1.21e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 43.12 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 495 LDALVKKSDGIASSeLEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISS-RLEqtqLREQLRMQYECSA 573
Cdd:TIGR01612 542 IEAGLKESYELAKN-WKKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYINKlKLE---LKEKIKNISDKNE 617
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 574 HLSIISDLEANVENLENELQAQSKRLEADIAEVLAAKvEQEKRAIKAEESlrkarwnnattaERLQEEFKSLSSQVSSAF 653
Cdd:TIGR01612 618 YIKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNK-DKIYSTIKSELS------------KIYEDDIDALYNELSSIV 684
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 654 SANerllvqarkeAAELQLQKSQLEELVQKAHEDIASVQEQHRMKIQQLLTLVDFKSNETERLVMELK-----------S 722
Cdd:TIGR01612 685 KEN----------AIDNTEDKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKkhihgeinkdlN 754
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 723 KT-DEFQNQKRCDEAKLNALSEEIDKLKTRIAKLSDER---------DNLLEKNEKKDMELAANGEKDM-VLQDKTAVIA 791
Cdd:TIGR01612 755 KIlEDFKNKEKELSNKINDYAKEKDELNKYKSKISEIKnhyndqiniDNIKDEDAKQNYDKSKEYIKTIsIKEDEIFKII 834
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 357146931 792 llnKEVTLLKDQVQTYLEELHTLKHSKNEK--------DEVIGKLQIDIGSLKLQ-YDNVKN 844
Cdd:TIGR01612 835 ---NEMKFMKDDFLNKVDKFINFENNCKEKidseheqfAELTNKIKAEISDDKLNdYEKKFN 893
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
433-967 |
1.31e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 42.65 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 433 AVKDLDEVLEQKNREISILQEE------TVEDHQEAQYEHALS--NVHTAGHKIDMSETSSYQGKEDELMLDALVKKSDG 504
Cdd:pfam02463 174 ALKKLIEETENLAELIIDLEELklqelkLKEQAKKALEYYQLKekLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 505 IASSELEEKIVELSD----EIELYKRDREDLEMQMEQLALDYEILKQENhDISSRLEQTQLREQLRMQYECSAHLSIISD 580
Cdd:pfam02463 254 ESSKQEIEKEEEKLAqvlkENKEEEKEKKLQEEELKLLAKEEEELKSEL-LKLERRKVDDEEKLKESEKEKKKAEKELKK 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 581 LEANVENLENELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKAR--WNNATTAERLQEEFKSLSSQVSSAFSANER 658
Cdd:pfam02463 333 EKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKleSERLSSAAKLKEEELELKSEEEKEAQLLLE 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 659 LLVQARKEAAELQLQKSQLEELVQKAhEDIASVQEQHRMKIQQLLTLVDFKSNETERLVMELKSKTDEFQNQKRCDEAKL 738
Cdd:pfam02463 413 LARQLEDLLKEEKKEELEILEEEEES-IELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLS 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 739 NALSEEIDKLKTRIAKLSDERDNLLEKNEKKDMELAANGEKDMVLQD---KTAVIALLNKEVTLLKDQVQTYLEELHTLK 815
Cdd:pfam02463 492 RQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVenyKVAISTAVIVEVSATADEVEERQKLVRALT 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 816 HSKNEKDEVIGKLQidigslklqyDNVKNLLSTKESEKSNLASQVLKLRRALESREGVKENGVTSDakdnqhsnSKRIKH 895
Cdd:pfam02463 572 ELPLGARKLRLLIP----------KLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEG--------ILKDTE 633
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 357146931 896 DTGSTGSSYAPPSTDRHDANDDCNEHSMRGAGAHADQSTKELDSLKEMNKAMQEELMELHERYSEISLKFAE 967
Cdd:pfam02463 634 LTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKE 705
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
311-894 |
1.34e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 42.73 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 311 DDVEKLRGEIGTLTRKLDVSDMELQTLRKqivKESRRGHDLSKEMSSLREERDAL--RRECEGLR----------GTKKT 378
Cdd:TIGR01612 1111 DEINKIKDDIKNLDQKIDHHIKALEEIKK---KSENYIDEIKAQINDLEDVADKAisNDDPEEIEkkienivtkiDKKKN 1187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 379 IHD-ANGSGKRLSDGEDPWSQVEELKQ-ELGHEKNLNadlRLQLQKMQES--NSELLLA-----VKDLDEVLEQKNreiS 449
Cdd:TIGR01612 1188 IYDeIKKLLNEIAEIEKDKTSLEEVKGiNLSYGKNLG---KLFLEKIDEEkkKSEHMIKameayIEDLDEIKEKSP---E 1261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 450 ILQEETVEDHQEAQYEhaLSNVHTAGHKiDMSETSSyqgKEDELMLDALVKKSDGIASSELEEKIVELSDEIELYKRDRE 529
Cdd:TIGR01612 1262 IENEMGIEMDIKAEME--TFNISHDDDK-DHHIISK---KHDENISDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQ 1335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 530 ----DLEMQMEQLALDYEILKQEN--HDISSRLEQTQLREQL--RMQYECSAHLSIISDLEANVENLENELQAQSKRLEA 601
Cdd:TIGR01612 1336 khnsDINLYLNEIANIYNILKLNKikKIIDEVKEYTKEIEENnkNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDK 1415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 602 DIAEVLaAKVEQEKRAIKAEESlrkarwNNATTAERLQEEFKSLSSQVSSAFSANER----LLVQARKEAAELQLQKSQL 677
Cdd:TIGR01612 1416 DIDECI-KKIKELKNHILSEES------NIDTYFKNADENNENVLLLFKNIEMADNKsqhiLKIKKDNATNDHDFNINEL 1488
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 678 EELVQKA--HEDIASVQEQHRMKIQQLLTlvDFKSNETERL----VMELKSKTDEFQNQKrcdeaklNALSEEIDKLKTR 751
Cdd:TIGR01612 1489 KEHIDKSkgCKDEADKNAKAIEKNKELFE--QYKKDVTELLnkysALAIKNKFAKTKKDS-------EIIIKEIKDAHKK 1559
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 752 I---AKLSDERDNLLEKNEKKDMELAANGEKD--MVLQDKTAVIALLNK--EVTLLKDQVQTYLEELHTLKH-----SKN 819
Cdd:TIGR01612 1560 FileAEKSEQKIKEIKKEKFRIEDDAAKNDKSnkAAIDIQLSLENFENKflKISDIKKKINDCLKETESIEKkissfSID 1639
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 820 EKD-------EVIGKLQIDIGSLKLQYDNVKNllstKESEKSNLASQVLKLRRALESREGVKENGVTSDAKDNQHSNSKR 892
Cdd:TIGR01612 1640 SQDtelkengDNLNSLQEFLESLKDQKKNIED----KKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEE 1715
|
..
gi 357146931 893 IK 894
Cdd:TIGR01612 1716 IE 1717
|
|
| Spc7 |
smart00787 |
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ... |
664-825 |
1.63e-03 |
|
Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.
Pssm-ID: 197874 [Multi-domain] Cd Length: 312 Bit Score: 41.54 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 664 RKEAAELQLQKSQLEELVQKAHEDIASVQEQHRMKIQQLLTLVDFKSNETERL----------VMELKSKTDEFQNQKRC 733
Cdd:smart00787 157 KEDYKLLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCDPTELDRAkeklkkllqeIMIKVKKLEELEEELQE 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 734 DEAKLNALSEEIDKLKTRIAKLsderDNLLEKNEKKDmelaangekdmvlqdktaviallNKEVTLLKDQVQTyLEELHT 813
Cdd:smart00787 237 LESKIEDLTNKKSELNTEIAEA----EKKLEQCRGFT-----------------------FKEIEKLKEQLKL-LQSLTG 288
|
170
....*....|..
gi 357146931 814 LKHSKNEKDEVI 825
Cdd:smart00787 289 WKITKLSGNTLS 300
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
490-893 |
1.78e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 1.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 490 EDELMLDALVKKSDGIAS--SELEEKIVELSDEIELYKRDREDLEMQMEQLalDYEILKQENHDISSRLEQTQLREQLRM 567
Cdd:COG4913 285 FAQRRLELLEAELEELRAelARLEAELERLEARLDALREELDELEAQIRGN--GGDRLEQLEREIERLERELEERERRRA 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 568 QYEcsahlSIISDLEANVENLENELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKARwnnaTTAERLQEEFKSLSS 647
Cdd:COG4913 363 RLE-----ALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLR----RELRELEAEIASLER 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 648 QVSSaFSANerlLVQARKE-AAELQLQKSQL------------EE-----------------LVQKAHEDIAS------- 690
Cdd:COG4913 434 RKSN-IPAR---LLALRDAlAEALGLDEAELpfvgelievrpeEErwrgaiervlggfaltlLVPPEHYAAALrwvnrlh 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 691 -------------VQEQHRMKI--QQLLTLVDFKSNE-TERLVMELKSK--------TDEFQNQKR-------------- 732
Cdd:COG4913 510 lrgrlvyervrtgLPDPERPRLdpDSLAGKLDFKPHPfRAWLEAELGRRfdyvcvdsPEELRRHPRaitragqvkgngtr 589
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 733 --CD---------------EAKLNALSEEIDKLKTRIAKLSDERDNL---LEKNEKKDMELAANGEKDMV---------- 782
Cdd:COG4913 590 heKDdrrrirsryvlgfdnRAKLAALEAELAELEEELAEAEERLEALeaeLDALQERREALQRLAEYSWDeidvasaere 669
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 783 LQDKTAVIALL---NKEVTLLKDQVQTYLEELHTLKHSKNEKDEVIGKLQIDIGSLKLQYDNVKNLLSTKESEKSNLASQ 859
Cdd:COG4913 670 IAELEAELERLdasSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749
|
490 500 510
....*....|....*....|....*....|....
gi 357146931 860 VLKLRRALESREGVkENGVTSDAKDNQHSNSKRI 893
Cdd:COG4913 750 LLEERFAAALGDAV-ERELRENLEERIDALRARL 782
|
|
| growth_prot_Scy |
NF041483 |
polarized growth protein Scy; |
532-754 |
1.85e-03 |
|
polarized growth protein Scy;
Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 42.51 E-value: 1.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 532 EMQMEQLALDYEILKQENHDISSRLEQTQLREQLRMQYECSAhlsiisdlEANV--ENLENELQAQSKRLEADI------ 603
Cdd:NF041483 82 QIQADQLRADAERELRDARAQTQRILQEHAEHQARLQAELHT--------EAVQrrQQLDQELAERRQTVESHVnenvaw 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 604 AEVLAAKVEQEKRAI------KAEESLRKARwnnaTTAERLQEEFKS-LSSQVSSAFSANERLLVQARKEAAELQLQKS- 675
Cdd:NF041483 154 AEQLRARTESQARRLldesraEAEQALAAAR----AEAERLAEEARQrLGSEAESARAEAEAILRRARKDAERLLNAASt 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 676 QLEELVQKAHE---DIASVQEQHRMKIQQLLTLVDFKSNETERLVMELKSKTDEFQNQKRCDEAKLNALSEEIDKLKTRI 752
Cdd:NF041483 230 QAQEATDHAEQlrsSTAAESDQARRQAAELSRAAEQRMQEAEEALREARAEAEKVVAEAKEAAAKQLASAESANEQRTRT 309
|
..
gi 357146931 753 AK 754
Cdd:NF041483 310 AK 311
|
|
| fliH |
PRK06669 |
flagellar assembly protein H; Validated |
641-774 |
2.48e-03 |
|
flagellar assembly protein H; Validated
Pssm-ID: 235850 [Multi-domain] Cd Length: 281 Bit Score: 41.16 E-value: 2.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 641 EFKSLSSQVSSAFSANERLLVQARKEAAELQLQKSQLEELVQkAHEDIASVQEQhrmKIQQLLTLVDFKSNETERLVMEL 720
Cdd:PRK06669 26 RFKVLSIKEKERLREEEEEQVEQLREEANDEAKEIIEEAEED-AFEIVEAAEEE---AKEELLKKTDEASSIIEKLQMQI 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 357146931 721 KSKTDEFQNQKR--CDEAK---------------LNALSEEIDKLKTRIAKLSDERDNLLEKNEKKDMELA 774
Cdd:PRK06669 102 EREQEEWEEELErlIEEAKaegyeegyekgreegLEEVRELIEQLNKIIEKLIKKREEILESSEEEIVELA 172
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
612-869 |
2.49e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 41.99 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 612 EQEKRAIKAEESLRKARWNNATTAERLQEEFK----SLSSQVSSAFSANERLL-----VQARKEAAELQLQKSQLEELvq 682
Cdd:COG5022 810 KEYRSYLACIIKLQKTIKREKKLRETEEVEFSlkaeVLIQKFGRSLKAKKRFSllkkeTIYLQSAQRVELAERQLQEL-- 887
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 683 kaHEDIASVQEQHRMKIQQLLTLVDFKSNETERLVMELKSKTDEFqnqkrcdeAKLNALSEEIDklktriakLSDERDNL 762
Cdd:COG5022 888 --KIDVKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELI--------ARLKKLLNNID--------LEEGPSIE 949
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 763 LEKNEKKDMELAANGEKDMVLQDKTAvialLNKEVTLLKDQVQTYLEELHTLKHSKNEKDEVIGKLQIDIGSLK---LQY 839
Cdd:COG5022 950 YVKLPELNKLHEVESKLKETSEEYED----LLKKSTILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKelpVEV 1025
|
250 260 270
....*....|....*....|....*....|..
gi 357146931 840 DNVKNLLSTKESEKSNLASQ--VLKLRRALES 869
Cdd:COG5022 1026 AELQSASKIISSESTELSILkpLQKLKGLLLL 1057
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
429-651 |
2.60e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.54 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 429 ELLLAVK---DLDEVLEQKNREISilQEETVEDHQEaqyEHALSNVHTAGHKIDMSETSSYQGKED-ELMLDALVKKSDG 504
Cdd:PHA02562 157 EDLLDISvlsEMDKLNKDKIRELN--QQIQTLDMKI---DHIQQQIKTYNKNIEEQRKKNGENIARkQNKYDELVEEAKT 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 505 IAS--SELEEKIVELSDEIELYKRD-------REDLEMQMEQLALDYEILkqENHDI----SSRLEQTQ-----LREQLR 566
Cdd:PHA02562 232 IKAeiEELTDELLNLVMDIEDPSAAlnklntaAAKIKSKIEQFQKVIKMY--EKGGVcptcTQQISEGPdritkIKDKLK 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 567 mqyECSAHLSIISDLEANVENLENELQAQSKR---LEADIAEV---LAAKVEQEKRAIKAEESLRKARWNNATTAERLQE 640
Cdd:PHA02562 310 ---ELQHSLEKLDTAIDELEEIMDEFNEQSKKlleLKNKISTNkqsLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386
|
250
....*....|.
gi 357146931 641 EFKSLSSQVSS 651
Cdd:PHA02562 387 ELDKIVKTKSE 397
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
509-757 |
2.69e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 41.86 E-value: 2.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 509 ELEEKIVELSDEIELYKRDREDLEMQME----QLALDYEILKQENHDISSRLEQTQLREQLRMQYECSAhlsiisdlEAN 584
Cdd:COG3096 303 EEQYRLVEMARELEELSARESDLEQDYQaasdHLNLVQTALRQQEKIERYQEDLEELTERLEEQEEVVE--------EAA 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 585 VENLENELQAQSKRLEAD-----IAEVLAAKVEQEKRAI---KAEESLRKAR---------WNNA-------------TT 634
Cdd:COG3096 375 EQLAEAEARLEAAEEEVDslksqLADYQQALDVQQTRAIqyqQAVQALEKARalcglpdltPENAedylaafrakeqqAT 454
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 635 AERLQEEFK-SLSSQVSSAFSANERLL----------------VQARKEAAELQLQKSQLEELVQKAHEDIASVQEQHRm 697
Cdd:COG3096 455 EEVLELEQKlSVADAARRQFEKAYELVckiageversqawqtaRELLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQN- 533
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 357146931 698 kIQQLLTLVDFKSN-------ETERLVMELKSKTDEFQNQKRCDEAKLNALSEEIDKLKTRIAKLSD 757
Cdd:COG3096 534 -AERLLEEFCQRIGqqldaaeELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAA 599
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
583-765 |
2.82e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 40.29 E-value: 2.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 583 ANVENLENELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKARwNNATTAERLQEEFKSLSSQVSsafsaNERLLVQ 662
Cdd:COG1579 20 DRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLE-LEIEEVEARIKKYEEQLGNVR-----NNKEYEA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 663 ARKEAAELQLQKSQLEELVQKAHEDIASVQEqhrmkiqqlltlvdfksneterlvmELKSKTDEFQNQKRCDEAKLNALS 742
Cdd:COG1579 94 LQKEIESLKRRISDLEDEILELMERIEELEE-------------------------ELAELEAELAELEAELEEKKAELD 148
|
170 180
....*....|....*....|...
gi 357146931 743 EEIDKLKTRIAKLSDERDNLLEK 765
Cdd:COG1579 149 EELAELEAELEELEAEREELAAK 171
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
316-566 |
2.89e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.54 E-value: 2.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 316 LRGEIGTLTRKLDVSDMELQTLRKQ--IVKESRRGHDLSKEMSSLREERDALRRECEGLRGTKKTIHDANGSGKRLSDGE 393
Cdd:COG3206 180 LEEQLPELRKELEEAEAALEEFRQKngLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 394 DPWSQVEELKQELgheKNLNADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETvedhqEAQYEHALSNVht 473
Cdd:COG3206 260 LQSPVIQQLRAQL---AELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASL-----EAELEALQARE-- 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 474 aghkidmsetssyqgkedelmldalvkksdgiasSELEEKIVELSDEIELYKRdredLEMQMEQLALDYEILKQENHDIS 553
Cdd:COG3206 330 ----------------------------------ASLQAQLAQLEARLAELPE----LEAELRRLEREVEVARELYESLL 371
|
250
....*....|...
gi 357146931 554 SRLEQTQLREQLR 566
Cdd:COG3206 372 QRLEEARLAEALT 384
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
310-639 |
3.24e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.56 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 310 EDDVEKLRGEIGTLTRKLDVSDMELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRGTKKTIHDANGSGKRL 389
Cdd:PRK02224 369 ESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAL 448
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 390 SDG-------------------EDPWSQVEELKQELgheknlnADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISI 450
Cdd:PRK02224 449 LEAgkcpecgqpvegsphvetiEEDRERVEELEAEL-------EDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDL 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 451 lqEETVEDHQE--AQYEHALSNVHTAGHKIDmsetSSYQGKEDELMLDALVKKSDGIASSELEEKIVELSDEIELYKRDR 528
Cdd:PRK02224 522 --EELIAERREtiEEKRERAEELRERAAELE----AEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIR 595
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 529 EDLEmQMEQLALDYEILKQENHDISSRleQTQLREQLRMQYEcsahlsIISDLEANV-ENLENELQAQSKRLEADIAEV- 606
Cdd:PRK02224 596 TLLA-AIADAEDEIERLREKREALAEL--NDERRERLAEKRE------RKRELEAEFdEARIEEAREDKERAEEYLEQVe 666
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 357146931 607 --LAAKVEQE----------KRAIKAEESLRKARWNNATTAERLQ 639
Cdd:PRK02224 667 ekLDELREERddlqaeigavENELEELEELRERREALENRVEALE 711
|
|
| ClyA_XaxA-like |
cd22657 |
Xenorhabdus nematophila alpha-xenorhabdolysin (XaxA) and Yersinia enterocolitica YaxA, and ... |
675-814 |
3.64e-03 |
|
Xenorhabdus nematophila alpha-xenorhabdolysin (XaxA) and Yersinia enterocolitica YaxA, and similar proteins; This model includes Xenorhabdus nematophila alpha-xenorhabdolysin (XaxA) and Yersinia enterocolitica YaxA, both parts of two-component alpha-helical pore-forming toxins (alpha-PFTs). The xaxAB genes encoding the XaxAB toxin have also been also identified in various plant and human pathogens. XaxAB triggers necrosis and apoptosis in both insect hemocytes and mammalian cells. Structure studies show that component A binds to component B's back, forming a subunit; twelve to fifteen of these subunits then conjoin as the pore-forming toxin. Component A stabilizes each subunit on the membrane and activates component B, which then punctures the membrane by swinging out its lower end. Similarly, Yersinia enterocolitica YaxA, encoded by the yaxAB gene, forms a pore predominantly composed of decamers of YaxA-YaxB heterodimers. Although both subunits bear membrane-active moieties, only YaxA is capable of binding to membranes by itself and YaxB is subsequently recruited to membrane-associated YaxA and induced to present its lytic transmembrane helices; pore formation then progresses by further oligomerization of YaxA-YaxB dimers. YaxAB has been found to be strongly upregulated by the Yersinia master regulator RovA, a transcriptional activator of Yersinia outer membrane protein invasion which is involved in bacterial attachment and invasion across the intestinal epithelium.
Pssm-ID: 439155 [Multi-domain] Cd Length: 306 Bit Score: 40.65 E-value: 3.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 675 SQLEELVQKAHEDIasvqEQHRMKIQQLLTLVD-FKSNETERLVMELKSKTDEFQNQKRcdEAKLNALSEEIDKLKTRIA 753
Cdd:cd22657 91 SDLGEYLEDIKEDI----KEYSKSTEEVKARLDdFRDELREELIPEVKLKLKLIDRNDL--DEEIEELNEEIDELDEEID 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 754 KLSDERDNLLE----------------------KNEKkdmelaANGEKDMVLQDKTAVIALLNKEVTLLK--DQVQTYLE 809
Cdd:cd22657 165 ELNKEYKKLVGlaftglaggpigllitggifgvKAEK------IRKERNELIAEREELIQKLKSKNRLLGslERLETDLQ 238
|
....*
gi 357146931 810 ELHTL 814
Cdd:cd22657 239 DLDIR 243
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
489-623 |
3.76e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.00 E-value: 3.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 489 KEDELMLDALVKKSDGIASSELEEKIVELSDEIELYKRDREDLEMQMEQlaLDYEILKQENhdiSSRLEQTQLREQLRMQ 568
Cdd:COG2433 390 LPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEE--KDERIERLER---ELSEARSEERREIRKD 464
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 357146931 569 YEcsahlsiISDLEANVENLENELQAQSKRLEAdiaevLAAKVEQEKRAIKAEES 623
Cdd:COG2433 465 RE-------ISRLDREIERLERELEEERERIEE-----LKRKLERLKELWKLEHS 507
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
333-810 |
5.37e-03 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 40.66 E-value: 5.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 333 ELQTLRKQIVKESRRGHDLSKEMSSLREERDALRRECEGLRGTKKTIHDANGSGKRLSDGEDPWSQVEELKQELghEKNL 412
Cdd:PRK01156 333 VLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDA--IKKE 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 413 NADLRLQLQKMQESNSELLLAVKDLDEVLEQKNREISILQEETV---------EDHQEAQYEHALSNVHTAGHKIDMSET 483
Cdd:PRK01156 411 LNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVcpvcgttlgEEKSNHIINHYNEKKSRLEEKIREIEI 490
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 484 SSyqGKEDELMLDaLVKKSDGIASSELEEKIVelsdeielYKRDREDLEMQMEQLALDYEILKqENHDISsrleqtqlrE 563
Cdd:PRK01156 491 EV--KDIDEKIVD-LKKRKEYLESEEINKSIN--------EYNKIESARADLEDIKIKINELK-DKHDKY---------E 549
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 564 QLRMQYEcSAHLsiiSDLEANVENLeneLQAQSKRLEADIaEVLAAKVEQEKRAIKAEESlrkarwnnattaeRLQEefk 643
Cdd:PRK01156 550 EIKNRYK-SLKL---EDLDSKRTSW---LNALAVISLIDI-ETNRSRSNEIKKQLNDLES-------------RLQE--- 605
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 644 sLSSQVSSAFSANERLLVQARKEAAELQLQKSQLEELvQKAHEDIASVQEQHRMKIQQLLTLVDFKSNETERLvmeLKSK 723
Cdd:PRK01156 606 -IEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQEN-KILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRI---NDIE 680
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 724 TDEFQNQKRCDEAKLN--ALSEEIDKLKTRIAKLSDERDNLLEKNEKKDMELAANGEKDMVLQ--DKTAVIALLNKEVT- 798
Cdd:PRK01156 681 DNLKKSRKALDDAKANraRLESTIEILRTRINELSDRINDINETLESMKKIKKAIGDLKRLREafDKSGVPAMIRKSASq 760
|
490
....*....|..
gi 357146931 799 LLKDQVQTYLEE 810
Cdd:PRK01156 761 AMTSLTRKYLFE 772
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
509-650 |
5.86e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.52 E-value: 5.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 509 ELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQENHDISSRLEQTQ-LREQLRMQYEcsahlsiISDLEANVEN 587
Cdd:COG1579 35 ELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRnNKEYEALQKE-------IESLKRRISD 107
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 357146931 588 LEN---ELQAQSKRLEADIAEVLAAKVEQEKRAIKAEESLRKARWNNATTAERLQEEFKSLSSQVS 650
Cdd:COG1579 108 LEDeilELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIP 173
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
388-840 |
7.42e-03 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 40.16 E-value: 7.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 388 RLSDGEDPWSQVEELKQELGHEKNLN----ADLRLQLQKMQESNSELLLAVKDLDevleqknREISILQEETVEdhQEAQ 463
Cdd:pfam01576 160 RISEFTSNLAEEEEKAKSLSKLKNKHeamiSDLEERLKKEEKGRQELEKAKRKLE-------GESTDLQEQIAE--LQAQ 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 464 YEHALSNVhtaGHKIDMSETSSYQGKEDELMLDALVKKSdgiasSELEEKIVELSDEIELYKRDREDLEMQMEQLALDYE 543
Cdd:pfam01576 231 IAELRAQL---AKKEEELQAALARLEEETAQKNNALKKI-----RELEAQISELQEDLESERAARNKAEKQRRDLGEELE 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 544 ILKQENHDIssrLEQTQLREQLRmqyecsahlsiiSDLEANVENLENELQAQSKRLEADIAEV----------LAAKVEQ 613
Cdd:pfam01576 303 ALKTELEDT---LDTTAAQQELR------------SKREQEVTELKKALEEETRSHEAQLQEMrqkhtqaleeLTEQLEQ 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 614 EKRaikAEESLRKARWNNATTAERLQEEFKSLSSQVSSAFSANERLLVQARK---EAAELQLQKSQLEELVQKAHEDIAS 690
Cdd:pfam01576 368 AKR---NKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQElqaRLSESERQRAELAEKLSKLQSELES 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 691 VqeqhrmkiQQLLTLVDFKSNETERLVMELKSKTDEFQNQkrcdeaklnaLSEEID---KLKTRIAKLSDERDNLLEKNE 767
Cdd:pfam01576 445 V--------SSLLNEAEGKNIKLSKDVSSLESQLQDTQEL----------LQEETRqklNLSTRLRQLEDERNSLQEQLE 506
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357146931 768 kKDMELAANGEKDmvlqdktavIALLNKEVTLLKDQVQTYLEELHTLKHSKNekdevigKLQIDIGSLKLQYD 840
Cdd:pfam01576 507 -EEEEAKRNVERQ---------LSTLQAQLSDMKKKLEEDAGTLEALEEGKK-------RLQRELEALTQQLE 562
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
511-755 |
8.00e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 40.33 E-value: 8.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 511 EEKIVELSDEIELYKRDREDLEMQMEQ----LALDYEILKQENHDISSRLEQTQLREQLRMQYECSAhlsiisdlEANVE 586
Cdd:PRK04863 306 QYRLVEMARELAELNEAESDLEQDYQAasdhLNLVQTALRQQEKIERYQADLEELEERLEEQNEVVE--------EADEQ 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 587 NLENELQAQS-----KRLEADIAEVLAAKVEQEKRAIK---AEESLRKAR-WNN-----ATTAERLQEEFK--------- 643
Cdd:PRK04863 378 QEENEARAEAaeeevDELKSQLADYQQALDVQQTRAIQyqqAVQALERAKqLCGlpdltADNAEDWLEEFQakeqeatee 457
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 644 --SLSSQVSSAFSANER--------------------------LLVQARKE---AAELQLQKSQLEELVQKAHEDIASVQ 692
Cdd:PRK04863 458 llSLEQKLSVAQAAHSQfeqayqlvrkiagevsrseawdvareLLRRLREQrhlAEQLQQLRMRLSELEQRLRQQQRAER 537
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 357146931 693 EQHRMKIQQLLTLVDFksNETERLVMELKSKTDEFQNQKRCDEAKLNALSEEIDKLKTRIAKL 755
Cdd:PRK04863 538 LLAEFCKRLGKNLDDE--DELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRL 598
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
508-609 |
8.50e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 40.32 E-value: 8.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 357146931 508 SELEEKIVELSDEIELYKRDREDLEMQMEQLALDYEILKQEN---HDISSRLEqtQLREQLRMQYECS----AHLSIISD 580
Cdd:COG3096 560 AELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARApawLAAQDALE--RLREQSGEALADSqevtAAMQQLLE 637
|
90 100
....*....|....*....|....*....
gi 357146931 581 LEANVENLENELQAQSKRLEADIAEVLAA 609
Cdd:COG3096 638 REREATVERDELAARKQALESQIERLSQP 666
|
|
| |
