|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08294 |
PRK08294 |
phenol 2-monooxygenase; Provisional |
3-609 |
1.14e-120 |
|
phenol 2-monooxygenase; Provisional
Pssm-ID: 236223 [Multi-domain] Cd Length: 634 Bit Score: 371.63 E-value: 1.14e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 3 EEVyDIVIVGAGPFGLFLSLCLSRW-GYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQLVAHtSARLYNVAFWD 81
Cdd:PRK08294 31 DEV-DVLIVGCGPAGLTLAAQLSAFpDITTRIVERKPGRLELGQADGIACRTMEMFQAFGFAERILKE-AYWINETAFWK 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 82 PDP-NSEGIHRTSNWPSCPPTIgARYPFtLTIHQGIIERVFLDEMSKCGTIVErPS---TIVGfLHDKENSTYPVSVTLK 157
Cdd:PRK08294 109 PDPaDPSTIVRTGRVQDTEDGL-SEFPH-VIVNQARVHDYFLDVMRNSPTRLE-PDygrEFVD-LEVDEEGEYPVTVTLR 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 158 SLD---TNVERTVRTKYLIGGEGTRSFIREQLGIKMQRKGPISAvWAVMDGVVRTNFPDIRKKCTIHSHS-GSVMVIPRE 233
Cdd:PRK08294 185 RTDgehEGEEETVRAKYVVGCDGARSRVRKAIGRELRGDSANHA-WGVMDVLAVTDFPDIRLKCAIQSASeGSILLIPRE 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 234 NN-LVRLYTQISSPDDPDWDPKRTATIQQAQDSIIKALKPYDITWDMVDWYSTYPIGQGLADSY---------SLDQRIF 303
Cdd:PRK08294 264 GGyLVRLYVDLGEVPPDERVAVRNTTVEEVIAKAQRILHPYTLDVKEVAWWSVYEVGQRLTDRFddvpaeeagTRLPRVF 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 304 IGGDACHTHSPKAGQGMNAGFHDALNLAWKIHAVEAGFADRSILESYEAERRYIAQQLLGFDAKYTKLFSQRlsSKDPSL 383
Cdd:PRK08294 344 IAGDACHTHSAKAGQGMNVSMQDGFNLGWKLAAVLSGRSPPELLHTYSAERQAIAQELIDFDREWSTMMAAP--PKEGGG 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 384 PESKEFTKLHKAAAEFTSGYGIVYPPNVFNWHPNHRAKSplfisdgTILTPGRCFPPATVTRLADSNPVHLEHEIPMNGS 463
Cdd:PRK08294 422 VDPAELQDYFVKHGRFTAGTATHYAPSLLTGEATHQDLA-------TGFPIGKRFHSAPVIRLADAKPVHLGHAATADGR 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 464 FRILIFAG--SLDKSRTALADFCRYIEE-PSSFYALFaTPELC-PDPYFEkhnphsrfftIAAVFMEEKDNVDISTLPRL 539
Cdd:PRK08294 495 WRIYAFADaaDPAGPGSALDALCEFLAEsPDSPLRRF-TPSGAdIDAVID----------VRAIFQQPHRELDLEDVPAL 563
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 315045818 540 LK--------AYHHHIYADDLvhksaaqPIGSIHKKLGFDTDRPGVVVIRPDGHVACILRLEEgtgtIDALNKYFGTF 609
Cdd:PRK08294 564 LLprkgrfglTDYEKVFCADL-------SGADIFDLRGIDRDRGAVVVVRPDQYVANVLPLDA----HAELAAFFAGF 630
|
|
| FAD_binding_3 |
pfam01494 |
FAD binding domain; This domain is involved in FAD binding in a number of enzymes. |
6-365 |
8.98e-66 |
|
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
Pssm-ID: 396193 [Multi-domain] Cd Length: 348 Bit Score: 219.12 E-value: 8.98e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQLVAHTSARLYNVAFWDPDPN 85
Cdd:pfam01494 2 TDVLIVGGGPAGLMLALLLARAGVRVVLVERHATTSVLPRAHGLNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYNTRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 86 SEGIHrtsnwpscpptIGARYPFTLTIHQGIIERVFLDEMSKCGTIVERPSTIVGFLHDKENstypVSVTLKSLDTNVER 165
Cdd:pfam01494 82 RADLD-----------FLTSPPRVTVYPQTELEPILVEHAEARGAQVRFGTEVLSLEQDGDG----VTAVVRDRRDGEEY 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 166 TVRTKYLIGGEGTRSFIREQLGIkmQRKGPISAVWAVMDGVVRT-NFPDIRKKCTIH-----SHSGSVMVIPREN-NLVR 238
Cdd:pfam01494 147 TVRAKYLVGCDGGRSPVRKTLGI--EFEGFEGVPFGSLDVLFDApDLSDPVERAFVHyliyaPHSRGFMVGPWRSaGRER 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 239 LYTQ-ISSPDDPDWDPKRTAtiQQAQDSIIKALKPYDITWDMvDWYSTYPIGQGLADSYSLDqRIFIGGDACHTHSPKAG 317
Cdd:pfam01494 225 YYVQvPWDEEVEERPEEFTD--EELKQRLRSIVGIDLALVEI-LWKSIWGVASRVATRYRKG-RVFLAGDAAHIHPPTGG 300
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 315045818 318 QGMNAGFHDALNLAWKIHAVEAGFADRSILESYEAERRYIAQQLLGFD 365
Cdd:pfam01494 301 QGLNTAIQDAFNLAWKLAAVLRGQAGESLLDTYSAERLPVAWAVVDFA 348
|
|
| UbiH |
COG0654 |
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ... |
6-375 |
2.97e-55 |
|
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 440419 [Multi-domain] Cd Length: 326 Bit Score: 190.53 E-value: 2.97e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQLVAHtSARLYNVAFWDPDPN 85
Cdd:COG0654 4 TDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRGIALSPRSLELLRRLGLWDRLLAR-GAPIRGIRVRDGSDG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 86 SEgIHRTsnwpscpPTIGARYPFTLTIHQGIIERVFLDEMSKCGTIVERPSTIVGFLHDKENstypVSVTLKSldtnvER 165
Cdd:COG0654 83 RV-LARF-------DAAETGLPAGLVVPRADLERALLEAARALGVELRFGTEVTGLEQDADG----VTVTLAD-----GR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 166 TVRTKYLIGGEGTRSFIREQLGIKMQRKG-PISAVWAVMDGVVRTNFpdirkkctihshsgsvmviprennlvrlytqis 244
Cdd:COG0654 146 TLRADLVVGADGARSAVRRLLGIGFTGRDyPQRALWAGVRTELRARL--------------------------------- 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 245 spddPDWDPkRTATIQQaqdsiikalkpyditwdmVDWYSTYPIGQGLADSYSlDQRIFIGGDACHTHSPKAGQGMNAGF 324
Cdd:COG0654 193 ----AAAGP-RLGELLE------------------LSPRSAFPLRRRRAERWR-RGRVVLLGDAAHTMHPLGGQGANLAL 248
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 315045818 325 HDALNLAWKIHAVEAGFADRSILESYEAERRYIAQQLLGFDAKYTKLFSQR 375
Cdd:COG0654 249 RDAAALAWKLAAALRGRDDEAALARYERERRPRAARVQRAADALGRLFHPD 299
|
|
| PHOX_C |
cd02979 |
FAD-dependent Phenol hydoxylase (PHOX) family, C-terminal TRX-fold domain; composed of ... |
435-609 |
3.34e-40 |
|
FAD-dependent Phenol hydoxylase (PHOX) family, C-terminal TRX-fold domain; composed of proteins similar to PHOX from the aerobic topsoil yeast Trichosporon cutaneum. PHOX is a flavoprotein monooxygenase that catalyzes the hydroxylation of phenol and simple phenol derivatives in the ortho position with the consumption of NADPH and oxygen. This is the first step in the biodegradation and detoxification of phenolic compounds. PHOX contains three domains. The substrate and FAD/NAD(P) binding sites are contained in the first two domains, which adopt a complicated folding pattern. The third or C-terminal domain contains a TRX fold and is involved in dimerization. The functional unit of PHOX is a dimer, although active tetramers of the recombinant enzyme can be isolated when overproduced in bacteria.
Pssm-ID: 239277 [Multi-domain] Cd Length: 167 Bit Score: 144.35 E-value: 3.34e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 435 GRCFPPATVTRLADSNPVHLEHEIPMNGSFRILIFAGSLDKSRT--ALADFCRYIEEPSSFyalfatpelcPDPYFEKHN 512
Cdd:cd02979 1 GRRFPSAPVVRQADALPVHLGHRLPADGRFRIYVFAGDIAPAQQksRLTQLCDALDSPDSF----------PLRYTPRGA 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 513 PHSRFFTIAAVFMEEKDNVDISTLPRLL-------KAYHHHIYADDLvhkSAAQPIGSIHKKLGFDTDRPGVVVIRPDGH 585
Cdd:cd02979 71 DPDSVFDVVTIHAAPRREIELLDLPAVLrpfgekkGWDYEKIYADDD---SYHEGHGDAYEKYGIDPERGAVVVVRPDQY 147
|
170 180
....*....|....*....|....
gi 315045818 586 VACILRLEEgtgtIDALNKYFGTF 609
Cdd:cd02979 148 VALVGPLDD----VEALEAYFAGF 167
|
|
| Ubi-OHases |
TIGR01988 |
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ... |
7-373 |
2.66e-19 |
|
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 273913 [Multi-domain] Cd Length: 385 Bit Score: 90.34 E-value: 2.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 7 DIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDV-----PTRTGRADGIQPRSVEILRNLGVKKQLVAHTSARLYNVAFWD 81
Cdd:TIGR01988 1 DIVIVGGGMVGLALALALARSGLKVALIEATPLpapadPGFDNRVSALSAASIRLLEKLGVWDKIEPARAQPIRDIHVSD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 82 pdpnsegihrtsnwpscpptigARYPFTLTIHQgiiERVFLDEMskcGTIVE--------------RPSTIVGFLHDKEN 147
Cdd:TIGR01988 81 ----------------------GGSFGALRFDA---DEIGLEAL---GYVVEnrvlqqalwerlqeLPNVTLLCPARVVE 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 148 STYP---VSVTLKSldtnvERTVRTKYLIGGEGTRSFIREQLGIKMQRKG-PISAVWAVmdgvVRTNFPdirkkctiHSH 223
Cdd:TIGR01988 133 LPRHsdhVELTLDD-----GQQLRARLLVGADGANSKVRQLAGIPTTGWDyGQSAVVAN----VKHERP--------HQG 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 224 --------SGSVMVIPRENNLVRLYtqisspddpdW--DPKRTATIQQAQD-SIIKALKpyditwDMVDWY--------- 283
Cdd:TIGR01988 196 tawerftpTGPLALLPLPDNRSSLV----------WtlPPEEAERLLALSDeEFLAELQ------RAFGSRlgaitlvge 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 284 -STYPIGQGLADSYsLDQRIFIGGDACHTHSPKAGQGMNAGFHDALNLAWKIH-AVEAG--FADRSILESYEAERRYIAQ 359
Cdd:TIGR01988 260 rHAFPLSLTHAKRY-VAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEdARRRGedIGSLRVLQRYERRRRFDNA 338
|
410
....*....|....
gi 315045818 360 QLLGFDAKYTKLFS 373
Cdd:TIGR01988 339 AMLGATDGLNRLFS 352
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08294 |
PRK08294 |
phenol 2-monooxygenase; Provisional |
3-609 |
1.14e-120 |
|
phenol 2-monooxygenase; Provisional
Pssm-ID: 236223 [Multi-domain] Cd Length: 634 Bit Score: 371.63 E-value: 1.14e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 3 EEVyDIVIVGAGPFGLFLSLCLSRW-GYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQLVAHtSARLYNVAFWD 81
Cdd:PRK08294 31 DEV-DVLIVGCGPAGLTLAAQLSAFpDITTRIVERKPGRLELGQADGIACRTMEMFQAFGFAERILKE-AYWINETAFWK 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 82 PDP-NSEGIHRTSNWPSCPPTIgARYPFtLTIHQGIIERVFLDEMSKCGTIVErPS---TIVGfLHDKENSTYPVSVTLK 157
Cdd:PRK08294 109 PDPaDPSTIVRTGRVQDTEDGL-SEFPH-VIVNQARVHDYFLDVMRNSPTRLE-PDygrEFVD-LEVDEEGEYPVTVTLR 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 158 SLD---TNVERTVRTKYLIGGEGTRSFIREQLGIKMQRKGPISAvWAVMDGVVRTNFPDIRKKCTIHSHS-GSVMVIPRE 233
Cdd:PRK08294 185 RTDgehEGEEETVRAKYVVGCDGARSRVRKAIGRELRGDSANHA-WGVMDVLAVTDFPDIRLKCAIQSASeGSILLIPRE 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 234 NN-LVRLYTQISSPDDPDWDPKRTATIQQAQDSIIKALKPYDITWDMVDWYSTYPIGQGLADSY---------SLDQRIF 303
Cdd:PRK08294 264 GGyLVRLYVDLGEVPPDERVAVRNTTVEEVIAKAQRILHPYTLDVKEVAWWSVYEVGQRLTDRFddvpaeeagTRLPRVF 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 304 IGGDACHTHSPKAGQGMNAGFHDALNLAWKIHAVEAGFADRSILESYEAERRYIAQQLLGFDAKYTKLFSQRlsSKDPSL 383
Cdd:PRK08294 344 IAGDACHTHSAKAGQGMNVSMQDGFNLGWKLAAVLSGRSPPELLHTYSAERQAIAQELIDFDREWSTMMAAP--PKEGGG 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 384 PESKEFTKLHKAAAEFTSGYGIVYPPNVFNWHPNHRAKSplfisdgTILTPGRCFPPATVTRLADSNPVHLEHEIPMNGS 463
Cdd:PRK08294 422 VDPAELQDYFVKHGRFTAGTATHYAPSLLTGEATHQDLA-------TGFPIGKRFHSAPVIRLADAKPVHLGHAATADGR 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 464 FRILIFAG--SLDKSRTALADFCRYIEE-PSSFYALFaTPELC-PDPYFEkhnphsrfftIAAVFMEEKDNVDISTLPRL 539
Cdd:PRK08294 495 WRIYAFADaaDPAGPGSALDALCEFLAEsPDSPLRRF-TPSGAdIDAVID----------VRAIFQQPHRELDLEDVPAL 563
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 315045818 540 LK--------AYHHHIYADDLvhksaaqPIGSIHKKLGFDTDRPGVVVIRPDGHVACILRLEEgtgtIDALNKYFGTF 609
Cdd:PRK08294 564 LLprkgrfglTDYEKVFCADL-------SGADIFDLRGIDRDRGAVVVVRPDQYVANVLPLDA----HAELAAFFAGF 630
|
|
| FAD_binding_3 |
pfam01494 |
FAD binding domain; This domain is involved in FAD binding in a number of enzymes. |
6-365 |
8.98e-66 |
|
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
Pssm-ID: 396193 [Multi-domain] Cd Length: 348 Bit Score: 219.12 E-value: 8.98e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQLVAHTSARLYNVAFWDPDPN 85
Cdd:pfam01494 2 TDVLIVGGGPAGLMLALLLARAGVRVVLVERHATTSVLPRAHGLNQRTMELLRQAGLEDRILAEGVPHEGMGLAFYNTRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 86 SEGIHrtsnwpscpptIGARYPFTLTIHQGIIERVFLDEMSKCGTIVERPSTIVGFLHDKENstypVSVTLKSLDTNVER 165
Cdd:pfam01494 82 RADLD-----------FLTSPPRVTVYPQTELEPILVEHAEARGAQVRFGTEVLSLEQDGDG----VTAVVRDRRDGEEY 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 166 TVRTKYLIGGEGTRSFIREQLGIkmQRKGPISAVWAVMDGVVRT-NFPDIRKKCTIH-----SHSGSVMVIPREN-NLVR 238
Cdd:pfam01494 147 TVRAKYLVGCDGGRSPVRKTLGI--EFEGFEGVPFGSLDVLFDApDLSDPVERAFVHyliyaPHSRGFMVGPWRSaGRER 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 239 LYTQ-ISSPDDPDWDPKRTAtiQQAQDSIIKALKPYDITWDMvDWYSTYPIGQGLADSYSLDqRIFIGGDACHTHSPKAG 317
Cdd:pfam01494 225 YYVQvPWDEEVEERPEEFTD--EELKQRLRSIVGIDLALVEI-LWKSIWGVASRVATRYRKG-RVFLAGDAAHIHPPTGG 300
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 315045818 318 QGMNAGFHDALNLAWKIHAVEAGFADRSILESYEAERRYIAQQLLGFD 365
Cdd:pfam01494 301 QGLNTAIQDAFNLAWKLAAVLRGQAGESLLDTYSAERLPVAWAVVDFA 348
|
|
| PRK07190 |
PRK07190 |
FAD-binding protein; |
1-407 |
1.55e-56 |
|
FAD-binding protein;
Pssm-ID: 235955 [Multi-domain] Cd Length: 487 Bit Score: 198.50 E-value: 1.55e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 1 MREEVYDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQL-----VAHTSARLY 75
Cdd:PRK07190 1 MSTQVTDVVIIGAGPVGLMCAYLGQLCGLNTVIVDKSDGPLEVGRADALNARTLQLLELVDLFDELyplgkPCNTSSVWA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 76 NVAFwdpdpnsegIHRTSNWpsCPPTIGARYPFTLTIHQGIIERVFLDEMSKCGTIVERPSTIVGFLHDKENSTypvsVT 155
Cdd:PRK07190 81 NGKF---------ISRQSSW--WEELEGCLHKHFLMLGQSYVEKLLDDKLKEAGAAVKRNTSVVNIELNQAGCL----TT 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 156 LksldTNVERtVRTKYLIGGEGTRSFIREQLGIKMQRKGPiSAVWAVMDGVVRTNFPDIRKKCTIHSHSGSVMVIPRENN 235
Cdd:PRK07190 146 L----SNGER-IQSRYVIGADGSRSFVRNHFNVPFEIIRP-QIIWAVIDGVIDTDFPKVPEIIVFQAETSDVAWIPREGE 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 236 LVRLYTQISSPDdpdwdpkrtATIQQAQDSIIKALKPYDITWDMVDWYSTYPIGQGLADSYSLDQRIFIGGDACHTHSPK 315
Cdd:PRK07190 220 IDRFYVRMDTKD---------FTLEQAIAKINHAMQPHRLGFKEIVWFSQFSVKESVAEHFFIQDRIFLAGDACHIHSVN 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 316 AGQGMNAGFHDALNLAWKIHAVEAGFADRSILESYEAERRYIAQQLLGFDAKYTKlfSQRLSSKDpslPESKEFTKLHKA 395
Cdd:PRK07190 291 GGQGLNTGLADAFNLIWKLNMVIHHGASPELLQSYEAERKPVAQGVIETSGELVR--STKYSANG---THAQDYVKIVEK 365
|
410
....*....|..
gi 315045818 396 AAEFTSGYGIVY 407
Cdd:PRK07190 366 RAGYITGMGIRY 377
|
|
| UbiH |
COG0654 |
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ... |
6-375 |
2.97e-55 |
|
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 440419 [Multi-domain] Cd Length: 326 Bit Score: 190.53 E-value: 2.97e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQLVAHtSARLYNVAFWDPDPN 85
Cdd:COG0654 4 TDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGRGIALSPRSLELLRRLGLWDRLLAR-GAPIRGIRVRDGSDG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 86 SEgIHRTsnwpscpPTIGARYPFTLTIHQGIIERVFLDEMSKCGTIVERPSTIVGFLHDKENstypVSVTLKSldtnvER 165
Cdd:COG0654 83 RV-LARF-------DAAETGLPAGLVVPRADLERALLEAARALGVELRFGTEVTGLEQDADG----VTVTLAD-----GR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 166 TVRTKYLIGGEGTRSFIREQLGIKMQRKG-PISAVWAVMDGVVRTNFpdirkkctihshsgsvmviprennlvrlytqis 244
Cdd:COG0654 146 TLRADLVVGADGARSAVRRLLGIGFTGRDyPQRALWAGVRTELRARL--------------------------------- 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 245 spddPDWDPkRTATIQQaqdsiikalkpyditwdmVDWYSTYPIGQGLADSYSlDQRIFIGGDACHTHSPKAGQGMNAGF 324
Cdd:COG0654 193 ----AAAGP-RLGELLE------------------LSPRSAFPLRRRRAERWR-RGRVVLLGDAAHTMHPLGGQGANLAL 248
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 315045818 325 HDALNLAWKIHAVEAGFADRSILESYEAERRYIAQQLLGFDAKYTKLFSQR 375
Cdd:COG0654 249 RDAAALAWKLAAALRGRDDEAALARYERERRPRAARVQRAADALGRLFHPD 299
|
|
| PRK06184 |
PRK06184 |
hypothetical protein; Provisional |
7-363 |
4.95e-55 |
|
hypothetical protein; Provisional
Pssm-ID: 235728 [Multi-domain] Cd Length: 502 Bit Score: 194.82 E-value: 4.95e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 7 DIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQLVAHTSA----RLY----NVA 78
Cdd:PRK06184 5 DVLIVGAGPTGLTLAIELARRGVSFRLIEKAPEPFPGSRGKGIQPRTQEVFDDLGVLDRVVAAGGLyppmRIYrddgSVA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 79 FWDPDPNSEgihrtsnwpscpPTIGARYPFTLTIHQGIIERVFLDEMSKCGTIVERPSTIVGFLHDKEnstypvSVTLKS 158
Cdd:PRK06184 85 ESDMFAHLE------------PTPDEPYPLPLMVPQWRTERILRERLAELGHRVEFGCELVGFEQDAD------GVTARV 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 159 LDTNVERTVRTKYLIGGEGTRSFIREQLGIKMQRK--GPISAVWA--VMDGVVRTN---FPdirkkctiHSHSGSVMVIP 231
Cdd:PRK06184 147 AGPAGEETVRARYLVGADGGRSFVRKALGIGFPGEtlGIDRMLVAdvSLTGLDRDAwhqWP--------DGDMGMIALCP 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 232 -RENNLVrlytQISSPDDPDWDPKRTATIQQAQDSIIKALKPYDITwdMVDWYSTYPIGQGLADSYSLDqRIFIGGDACH 310
Cdd:PRK06184 219 lPGTDLF----QIQAPLPPGGEPDLSADGLTALLAERTGRTDIRLH--SVTWASAFRMNARLADRYRVG-RVFLAGDAAH 291
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 315045818 311 THSPKAGQGMNAGFHDALNLAWKIHAVEAGfADRSILESYEAERRYIAQQLLG 363
Cdd:PRK06184 292 VHPPAGGQGLNTSVQDAYNLGWKLAAVLAG-APEALLDTYEEERRPVAAAVLG 343
|
|
| Phe_hydrox_dim |
pfam07976 |
Phenol hydroxylase, C-terminal dimerization domain; Phenol hydroxylase acts a homodimer, to ... |
399-574 |
4.17e-43 |
|
Phenol hydroxylase, C-terminal dimerization domain; Phenol hydroxylase acts a homodimer, to hydroxylates phenol to catechol or similar product. The enzyme is comprised of three domains. The first two domains from the active site. The third domain, this domain, is involved in forming the dimerization interface. The domain adopts a thioredoxin-like fold.
Pssm-ID: 429765 Cd Length: 166 Bit Score: 152.30 E-value: 4.17e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 399 FTSGYGIVYPPNVFNWHPNHRAKSplfisdgTILTPGRCFPPATVTRLADSNPVHLEHEIPMNGSFRILIFAG--SLDKS 476
Cdd:pfam07976 1 FTSGVGVDYGPSILVAGTSHQNLA-------SGLPVGRRFPSAKVVRQADANPVHLQDELPSDGRFRILVFAGdiSDPAQ 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 477 RTALADFCRYIEEPSSFYALFaTPelcpdpyfeKHNPHSRFFTIAAVFMEEKDNVDISTLPRLLKAY-------HHHIYA 549
Cdd:pfam07976 74 KSRLEALADYLSSSSSFLSRY-TP---------AGADIDSVFDVLLIHSAPRTEVELEDLPEVLRPFdgklgwdYWKVYV 143
|
170 180
....*....|....*....|....*
gi 315045818 550 DDLVHKSAAqpiGSIHKKLGFDTDR 574
Cdd:pfam07976 144 DDESYHEGG---GDAYEKYGIDPKR 165
|
|
| PRK06126 |
PRK06126 |
hypothetical protein; Provisional |
7-370 |
4.17e-41 |
|
hypothetical protein; Provisional
Pssm-ID: 235704 [Multi-domain] Cd Length: 545 Bit Score: 157.08 E-value: 4.17e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 7 DIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQ-------------------LV 67
Cdd:PRK06126 9 PVLIVGGGPVGLALALDLGRRGVDSILVERKDGTAFNPKANTTSARSMEHFRRLGIADEvrsaglpvdyptdiayftrLT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 68 AHTSARLYNVAFWDPDPNSEGihRTSNWPScpPTIGARYPftltihQGIIERVFLDEMSKCGTIVERPST-IVGFLHDKE 146
Cdd:PRK06126 89 GYELARFRLPSAREAITPVGG--PDGSWPS--PELPHRIP------QKYLEPILLEHAAAQPGVTLRYGHrLTDFEQDAD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 147 NstypVSVTLKSLDTNVERTVRTKYLIGGEGTRSFIREQLGIKMQRKGPISAVWAVMdgvVRTnfPDIRKkctIHSHSGS 226
Cdd:PRK06126 159 G----VTATVEDLDGGESLTIRADYLVGCDGARSAVRRSLGISYEGTSGLQRDLSIY---IRA--PGLAA---LVGHDPA 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 227 VMVI---PRENNLV---------RLYTQISSPDDPDWDPKR-TATIQQAQDSIIkalkPYDITwDMVDWYSTypigQGLA 293
Cdd:PRK06126 227 WMYWlfnPDRRGVLvaidgrdewLFHQLRGGEDEFTIDDVDaRAFVRRGVGEDI----DYEVL-SVVPWTGR----RLVA 297
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 315045818 294 DSYSlDQRIFIGGDACHTHSPKAGQGMNAGFHDALNLAWKIHAVEAGFADRSILESYEAERRYIAQQLLGFDAKYTK 370
Cdd:PRK06126 298 DSYR-RGRVFLAGDAAHLFTPTGGYGMNTGIGDAVNLAWKLAAVLNGWAGPALLDSYEAERRPIAARNTDYARRNAD 373
|
|
| PHOX_C |
cd02979 |
FAD-dependent Phenol hydoxylase (PHOX) family, C-terminal TRX-fold domain; composed of ... |
435-609 |
3.34e-40 |
|
FAD-dependent Phenol hydoxylase (PHOX) family, C-terminal TRX-fold domain; composed of proteins similar to PHOX from the aerobic topsoil yeast Trichosporon cutaneum. PHOX is a flavoprotein monooxygenase that catalyzes the hydroxylation of phenol and simple phenol derivatives in the ortho position with the consumption of NADPH and oxygen. This is the first step in the biodegradation and detoxification of phenolic compounds. PHOX contains three domains. The substrate and FAD/NAD(P) binding sites are contained in the first two domains, which adopt a complicated folding pattern. The third or C-terminal domain contains a TRX fold and is involved in dimerization. The functional unit of PHOX is a dimer, although active tetramers of the recombinant enzyme can be isolated when overproduced in bacteria.
Pssm-ID: 239277 [Multi-domain] Cd Length: 167 Bit Score: 144.35 E-value: 3.34e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 435 GRCFPPATVTRLADSNPVHLEHEIPMNGSFRILIFAGSLDKSRT--ALADFCRYIEEPSSFyalfatpelcPDPYFEKHN 512
Cdd:cd02979 1 GRRFPSAPVVRQADALPVHLGHRLPADGRFRIYVFAGDIAPAQQksRLTQLCDALDSPDSF----------PLRYTPRGA 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 513 PHSRFFTIAAVFMEEKDNVDISTLPRLL-------KAYHHHIYADDLvhkSAAQPIGSIHKKLGFDTDRPGVVVIRPDGH 585
Cdd:cd02979 71 DPDSVFDVVTIHAAPRREIELLDLPAVLrpfgekkGWDYEKIYADDD---SYHEGHGDAYEKYGIDPERGAVVVVRPDQY 147
|
170 180
....*....|....*....|....
gi 315045818 586 VACILRLEEgtgtIDALNKYFGTF 609
Cdd:cd02979 148 VALVGPLDD----VEALEAYFAGF 167
|
|
| PRK08244 |
PRK08244 |
monooxygenase; |
6-472 |
5.79e-36 |
|
monooxygenase;
Pssm-ID: 236199 [Multi-domain] Cd Length: 493 Bit Score: 141.42 E-value: 5.79e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQLVA--------HTSARLYNV 77
Cdd:PRK08244 3 YEVIIIGGGPVGLMLASELALAGVKTCVIERLKETVPYSKALTLHPRTLEILDMRGLLERFLEkgrklpsgHFAGLDTRL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 78 AFWDPDpnsegihrtsnwpscpptigARYPFTLTIHQGIIERVFLDEMSKCGTIVERPSTIVGFLHDKEnstypvSVTLK 157
Cdd:PRK08244 83 DFSALD--------------------TSSNYTLFLPQAETEKVLEEHARSLGVEIFRGAEVLAVRQDGD------GVEVV 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 158 SLDTNVERTVRTKYLIGGEGTRSFIREQLGIKMQrkGPISAVWAVMDGVVRTNFPDIRKKCTIhSHSGSVMVIPRENNLV 237
Cdd:PRK08244 137 VRGPDGLRTLTSSYVVGADGAGSIVRKQAGIAFP--GTDATFTAMLGDVVLKDPPPSSVLSLC-TREGGVMIVPLSGGIY 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 238 RLYtqISSPDDPDWDPKRTATIQQAQDSIIKALKPyDITWDMVDWYSTYPIGQGLADSYSlDQRIFIGGDACHTHSPKAG 317
Cdd:PRK08244 214 RVL--IIDPERPQVPKDEPVTLEELKTSLIRICGT-DFGLNDPVWMSRFGNATRQAERYR-SGRIFLAGDAAHIHFPAGG 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 318 QGMNAGFHDALNLAWKIHAVEAGFADRSILESYEAERRYIAQQLLGFDAKYTKL--FSQRLSSKDPSLPESKEFTKLHKA 395
Cdd:PRK08244 290 QGLNVGLQDAMNLGWKLAAAIKGWAPDWLLDSYHAERHPVGTALLRNTEVQTKLfdFTRPGLALRSMLSDLLGFPEVNRY 369
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 315045818 396 AAEFTSGYGIVYPPNvfNWHPNHRAKsplfisdgtiltpGRCFPPATVTrLADSNPVHLeHEIPMNGSFRILIFAGS 472
Cdd:PRK08244 370 LAGQISALDVHYEPD--AEMPPHPLN-------------GKRLPDLELT-LSDGESERL-YSLLHKGTFLLLSFGSE 429
|
|
| mhpA |
PRK06183 |
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase; |
6-355 |
7.17e-33 |
|
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
Pssm-ID: 235727 [Multi-domain] Cd Length: 500 Bit Score: 132.34 E-value: 7.17e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNVKHIDnrdvptrtgRADGI--QPRSV----EILRNL---GVKKQLVAHTSA---- 72
Cdd:PRK06183 11 TDVVIVGAGPVGLTLANLLGQYGVRVLVLE---------RWPTLydLPRAVgiddEALRVLqaiGLADEVLPHTTPnhgm 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 73 RLYN--------VAFWDPDPnsegihrtSNWPscpptigARYPFtltiHQGIIERVFLDEMSKC-GTIVERPSTIVGFLH 143
Cdd:PRK06183 82 RFLDakgrclaeIARPSTGE--------FGWP-------RRNAF----HQPLLEAVLRAGLARFpHVRVRFGHEVTALTQ 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 144 DKENstypVSVTLKSLDTnVERTVRTKYLIGGEGTRSFIREQLGIKMQRKGPiSAVWAVMDgVVRTNFPDirkkctihSH 223
Cdd:PRK06183 143 DDDG----VTVTLTDADG-QRETVRARYVVGCDGANSFVRRTLGVPFEDLTF-PERWLVVD-VLIANDPL--------GG 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 224 SGSVMVI-PRennlvRLYTQISSPDD---------PDWDPKRTATIQqaqdSIIKALKPYDITWDMVDW--YSTYPIGQG 291
Cdd:PRK06183 208 PHTYQYCdPA-----RPYTSVRLPHGrrrwefmllPGETEEQLASPE----NVWRLLAPWGPTPDDAELirHAVYTFHAR 278
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 315045818 292 LADSYSlDQRIFIGGDACHTHSPKAGQGMNAGFHDALNLAWKIHAVEAGFADRSILESYEAERR 355
Cdd:PRK06183 279 VADRWR-SGRVLLAGDAAHLMPPFAGQGMNSGIRDAANLAWKLAAVLRGRAGDALLDTYEQERR 341
|
|
| PRK06834 |
PRK06834 |
hypothetical protein; Provisional |
1-362 |
1.15e-27 |
|
hypothetical protein; Provisional
Pssm-ID: 235870 [Multi-domain] Cd Length: 488 Bit Score: 116.66 E-value: 1.15e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 1 MREevYDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTG-RADGIQPRSVEILRNLGVKKQLVAH-TSARLYNVA 78
Cdd:PRK06834 1 MTE--HAVVIAGGGPTGLMLAGELALAGVDVAIVERRPNQELVGsRAGGLHARTLEVLDQRGIADRFLAQgQVAQVTGFA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 79 FWDPDpnsegihrTSNWPScpptigaRYPFTLTIHQGIIERVFLDEMSKCGTIVERPSTIVGFLHDkenstypvsvtlks 158
Cdd:PRK06834 79 ATRLD--------ISDFPT-------RHNYGLALWQNHIERILAEWVGELGVPIYRGREVTGFAQD-------------- 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 159 lDTNVE------RTVRTKYLIGGEGTRSFIREQLGIKMQRKGP-ISAVWAVMDGVVRTNFPDIRKKCTIHS-----HSGS 226
Cdd:PRK06834 130 -DTGVDvelsdgRTLRAQYLVGCDGGRSLVRKAAGIDFPGWDPtTSYLIAEVEMTEEPEWGVHRDALGIHAfgrleDEGP 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 227 VMVIPRENNLVRlytqissPDDPDWDPKRTATIqqaqdsiikALKPYDITWDMVDWYSTYPIGQGLADSYSlDQRIFIGG 306
Cdd:PRK06834 209 VRVMVTEKQVGA-------TGEPTLDDLREALI---------AVYGTDYGIHSPTWISRFTDMARQAASYR-DGRVLLAG 271
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 315045818 307 DACHTHSPKAGQGMNAGFHDALNLAWKIHAVEAGFADRSILESYEAERRYIAQQLL 362
Cdd:PRK06834 272 DAAHVHSPVGGQGLNTGVQDAVNLGWKLAQVVKGTSPESLLDTYHAERHPVAARVL 327
|
|
| Ubi-OHases |
TIGR01988 |
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ... |
7-373 |
2.66e-19 |
|
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 273913 [Multi-domain] Cd Length: 385 Bit Score: 90.34 E-value: 2.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 7 DIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDV-----PTRTGRADGIQPRSVEILRNLGVKKQLVAHTSARLYNVAFWD 81
Cdd:TIGR01988 1 DIVIVGGGMVGLALALALARSGLKVALIEATPLpapadPGFDNRVSALSAASIRLLEKLGVWDKIEPARAQPIRDIHVSD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 82 pdpnsegihrtsnwpscpptigARYPFTLTIHQgiiERVFLDEMskcGTIVE--------------RPSTIVGFLHDKEN 147
Cdd:TIGR01988 81 ----------------------GGSFGALRFDA---DEIGLEAL---GYVVEnrvlqqalwerlqeLPNVTLLCPARVVE 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 148 STYP---VSVTLKSldtnvERTVRTKYLIGGEGTRSFIREQLGIKMQRKG-PISAVWAVmdgvVRTNFPdirkkctiHSH 223
Cdd:TIGR01988 133 LPRHsdhVELTLDD-----GQQLRARLLVGADGANSKVRQLAGIPTTGWDyGQSAVVAN----VKHERP--------HQG 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 224 --------SGSVMVIPRENNLVRLYtqisspddpdW--DPKRTATIQQAQD-SIIKALKpyditwDMVDWY--------- 283
Cdd:TIGR01988 196 tawerftpTGPLALLPLPDNRSSLV----------WtlPPEEAERLLALSDeEFLAELQ------RAFGSRlgaitlvge 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 284 -STYPIGQGLADSYsLDQRIFIGGDACHTHSPKAGQGMNAGFHDALNLAWKIH-AVEAG--FADRSILESYEAERRYIAQ 359
Cdd:TIGR01988 260 rHAFPLSLTHAKRY-VAPRLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEdARRRGedIGSLRVLQRYERRRRFDNA 338
|
410
....*....|....
gi 315045818 360 QLLGFDAKYTKLFS 373
Cdd:TIGR01988 339 AMLGATDGLNRLFS 352
|
|
| PRK08132 |
PRK08132 |
FAD-dependent oxidoreductase; Provisional |
8-358 |
4.29e-17 |
|
FAD-dependent oxidoreductase; Provisional
Pssm-ID: 236158 [Multi-domain] Cd Length: 547 Bit Score: 84.53 E-value: 4.29e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 8 IVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVpTRTG-RADGIQPRSVEILRNLGVKKQLVAHTSArlYNVA--FWDPDP 84
Cdd:PRK08132 26 VVVVGAGPVGLALAIDLAQQGVPVVLLDDDDT-LSTGsRAICFAKRSLEIFDRLGCGERMVDKGVS--WNVGkvFLRDEE 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 85 nsegihrTSNWPSCPPTiGARYPFTLTIHQGIIERVFLDEMSKCGTIVERPSTIVgflhdkenstypvsVTLKSLDTNVE 164
Cdd:PRK08132 103 -------VYRFDLLPEP-GHRRPAFINLQQYYVEGYLVERAQALPNIDLRWKNKV--------------TGLEQHDDGVT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 165 RTVRT---------KYLIGGEGTRSFIREQLGIKMQ------RkgpisavWAVMDGVVRTNFPDIRkkctiH------SH 223
Cdd:PRK08132 161 LTVETpdgpytleaDWVIACDGARSPLREMLGLEFEgrtfedR-------FLIADVKMKADFPTER-----WfwfdppFH 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 224 SG-SVMVIPRENNLVRLYTQISSPDDPDWDPKRTATIQQaqdsiIKALKPYDITWDMvDWYSTYPIGQGLADSYSLDqRI 302
Cdd:PRK08132 229 PGqSVLLHRQPDNVWRIDFQLGWDADPEAEKKPENVIPR-----VRALLGEDVPFEL-EWVSVYTFQCRRMDRFRHG-RV 301
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 315045818 303 FIGGDACHTHSPKAGQGMNAGFHDALNLAWKIHAVEAGFADRSILESYEAERRYIA 358
Cdd:PRK08132 302 LFAGDAAHQVSPFGARGANSGIQDADNLAWKLALVLRGRAPDSLLDSYASEREFAA 357
|
|
| PRK07364 |
PRK07364 |
FAD-dependent hydroxylase; |
6-375 |
1.96e-15 |
|
FAD-dependent hydroxylase;
Pssm-ID: 236001 [Multi-domain] Cd Length: 415 Bit Score: 78.91 E-value: 1.96e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNR--DVPTRTGRADGIQPRSVEILRNLGVKKQLVAHtSARLYNVAFWDPD 83
Cdd:PRK07364 19 YDVAIVGGGIVGLTLAAALKDSGLRIALIEAQpaEAAAAKGQAYALSLLSARIFEGIGVWEKILPQ-IGKFRQIRLSDAD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 84 -PNSEgihrtsnwPSCPPTIGARYPFTLTIHQGIIErVFLDEMSKCGTIVERPSTIVGFLHDKENStypVSVTLKSldTN 162
Cdd:PRK07364 98 yPGVV--------KFQPTDLGTEALGYVGEHQVLLE-ALQEFLQSCPNITWLCPAEVVSVEYQQDA---ATVTLEI--EG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 163 VERTVRTKYLIGGEGTRSFIREQLGIKMQR-KGPISAVWAVMDgvvrtnfPDirkkctiHSH----------SGSVMVIP 231
Cdd:PRK07364 164 KQQTLQSKLVVAADGARSPIRQAAGIKTKGwKYWQSCVTATVK-------HE-------APHndiayerfwpSGPFAILP 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 232 RENNLVRL-YTQisspddPDWDPKRTATIQQAQdsIIKALKPY------DITwdMVDWYSTYPIGQGLADSYSLDqRIFI 304
Cdd:PRK07364 230 LPGNRCQIvWTA------PHAQAKALLALPEAE--FLAELQQRygdqlgKLE--LLGDRFLFPVQLMQSDRYVQH-RLAL 298
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 315045818 305 GGDACHTHSPKAGQGMNAGFHDALNLAWKIH-AVEAG--FADRSILESYEAERRYIAQQLLGFDAKYTKLFSQR 375
Cdd:PRK07364 299 VGDAAHCCHPVGGQGLNLGIRDAAALAQVLQtAHQRGedIGSLAVLKRYERWRKRENWLILGFTDLLDRLFSNQ 372
|
|
| COQ6 |
TIGR01989 |
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ... |
6-373 |
8.84e-12 |
|
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone
Pssm-ID: 273914 [Multi-domain] Cd Length: 437 Bit Score: 67.47 E-value: 8.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLsrwGYN-------VKHIDNRDVP------------TRTGRADGIQPRSVEILRNLGVKKQL 66
Cdd:TIGR01989 1 FDVVIVGGGPVGLALAAAL---GNNpltkdlkVLLLDAVDNPklksrnyekpdgPYSNRVSSITPASISFFKKIGAWDHI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 67 VAHTSARLYNVAFWDPdpNSEGIHRTSNWPSCPPTIGarypftltihqgIIERVFLdemskCGTIVERPSTIVGFLHDKE 146
Cdd:TIGR01989 78 QSDRIQPFGRMQVWDG--CSLALIRFDRDNGKEDMAC------------IIENDNI-----QNSLYNRLQEYNGDNVKIL 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 147 NSTYPVSVTLKSLDTNVE-----------RTVRTKYLIGGEGTRSFIREQLGIKM------------------------- 190
Cdd:TIGR01989 139 NPARLISVTIPSKYPNDNsnwvhitlsdgQVLYTKLLIGADGSNSNVRKAANIDTtgwnynqhavvatlkleeatendva 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 191 -QR---KGPI----------SAVWAvmdgvvrtnfpdirkkcTIHSHSGSVMVIPRENnLVRLYTQISSPDDPDWDpkRT 256
Cdd:TIGR01989 219 wQRflpTGPIallplpdnnsTLVWS-----------------TSPEEALRLLSLPPED-FVDALNAAFDLGYSDHP--YS 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 257 ATIQQAQDSIIKALK------------PYDITWDMVDWYSTYPIGQGLADSYSLDqRIFIGGDACHTHSPKAGQGMNAGF 324
Cdd:TIGR01989 279 YLLDYAMEKLNEDIGfrtegskscfqvPPRVIGVVDKSRAAFPLGLGHADEYVTK-RVALVGDAAHRVHPLAGQGVNLGF 357
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 315045818 325 HDALNLAWKI-HAVEAG--FADRSILESYEAERRYIAQQLLGFDAKYTKLFS 373
Cdd:TIGR01989 358 GDVASLVKALaEAVSVGadIGSISSLKPYERERYAKNVVLLGLVDKLHKLYA 409
|
|
| FixC |
COG0644 |
Dehydrogenase (flavoprotein) [Energy production and conversion]; |
13-249 |
3.65e-11 |
|
Dehydrogenase (flavoprotein) [Energy production and conversion];
Pssm-ID: 440409 [Multi-domain] Cd Length: 281 Bit Score: 64.22 E-value: 3.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 13 AGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQLVAHtsarLYNVAFWDPDPNSegihrt 92
Cdd:COG0644 1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDKICGGGLLPRALEELEPLGLDEPLERP----VRGARFYSPGGKS------ 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 93 snwpscpPTIGARYPFTLTIHQGIIERVFLDEMSKCGTIVERPSTIVGFLHDKENstypVSVTLKSldtnvERTVRTKYL 172
Cdd:COG0644 71 -------VELPPGRGGGYVVDRARFDRWLAEQAEEAGAEVRTGTRVTDVLRDDGR----VVVRTGD-----GEEIRADYV 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 173 IGGEGTRSFIREQLGIKMQRKGP---ISAVWAVMDGVVRTNFPDIRKKCTIHS--HSGSVMVIPRENNLVRLYTQISSPD 247
Cdd:COG0644 135 VDADGARSLLARKLGLKRRSDEPqdyALAIKEHWELPPLEGVDPGAVEFFFGEgaPGGYGWVFPLGDGRVSVGIPLGGPR 214
|
..
gi 315045818 248 DP 249
Cdd:COG0644 215 PR 216
|
|
| PRK07608 |
PRK07608 |
UbiH/UbiF family hydroxylase; |
6-355 |
2.44e-09 |
|
UbiH/UbiF family hydroxylase;
Pssm-ID: 181057 [Multi-domain] Cd Length: 388 Bit Score: 59.58 E-value: 2.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTG-----RADGIQPRSVEILRNLGVKKQLVAhtsARLYNVA-- 78
Cdd:PRK07608 6 FDVVVVGGGLVGASLALALAQSGLRVALLAPRAPPRPADdawdsRVYAISPSSQAFLERLGVWQALDA---ARLAPVYdm 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 79 --FWDPDpnseGIHRTSNWPSCPPTIGarypftLTIHQGIIERVFLDEMSKCGTIVERPSTIVGFlhdkENSTYPVSVTL 156
Cdd:PRK07608 83 rvFGDAH----ARLHFSAYQAGVPQLA------WIVESSLIERALWAALRFQPNLTWFPARAQGL----EVDPDAATLTL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 157 KSldtnvERTVRTKYLIGGEGTRSFIREQLGIKMQRKgPISAVwavmdGVVrTNFpdirkKCTiHSHSGSVMVIPRENNL 236
Cdd:PRK07608 149 AD-----GQVLRADLVVGADGAHSWVRSQAGIKAERR-PYRQT-----GVV-ANF-----KAE-RPHRGTAYQWFRDDGI 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 237 VRLY----TQIS-----SPDDPD----WDPKR-TATIQQAQDSIIKALKPYditwdmvdwysTYPIGQGLAdSYSLDQ-- 300
Cdd:PRK07608 211 LALLplpdGHVSmvwsaRTAHADellaLSPEAlAARVERASGGRLGRLECV-----------TPAAGFPLR-LQRVDRlv 278
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 315045818 301 --RIFIGGDACHTHSPKAGQGMNAGFHDALNLAWKIHAVEA--GFADRSILESYEAERR 355
Cdd:PRK07608 279 apRVALVGDAAHLIHPLAGQGMNLGLRDVAALADVLAGREPfrDLGDLRLLRRYERARR 337
|
|
| PRK06185 |
PRK06185 |
FAD-dependent oxidoreductase; |
1-331 |
7.40e-08 |
|
FAD-dependent oxidoreductase;
Pssm-ID: 235729 [Multi-domain] Cd Length: 407 Bit Score: 54.87 E-value: 7.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 1 MREEVYDIVIVGAGPFGLFLSLCLSRWGYNV----KHID-NRDVptrtgRADGIQPRSVEILRNLGVKKQLVAHTSARLY 75
Cdd:PRK06185 2 AEVETTDCCIVGGGPAGMMLGLLLARAGVDVtvleKHADfLRDF-----RGDTVHPSTLELMDELGLLERFLELPHQKVR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 76 NVAFWDPdpnseGIHRTSNWPSCPPTigaRYPFTLTIHQgiieRVFLD----EMSKCGTIVERPSTIV-GFLHDKEnsty 150
Cdd:PRK06185 77 TLRFEIG-----GRTVTLADFSRLPT---PYPYIAMMPQ----WDFLDflaeEASAYPNFTLRMGAEVtGLIEEGG---- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 151 pvSVT-LKSLDTNVERTVRTKYLIGGEGTRSFIREQLGIKMQRKG-PISAVWavmdgvvrtnF-----PDIRKKCTIHSH 223
Cdd:PRK06185 141 --RVTgVRARTPDGPGEIRADLVVGADGRHSRVRALAGLEVREFGaPMDVLW----------FrlprePDDPESLMGRFG 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 224 SGSVMV-IPRENnlvrlYTQ----ISSPDDPDW-----DP--KRTATIQQAQDSIIKALKpydiTWDMVDWYSTYPigqG 291
Cdd:PRK06185 209 PGQGLImIDRGD-----YWQcgyvIPKGGYAALraaglEAfrERVAELAPELADRVAELK----SWDDVKLLDVRV---D 276
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 315045818 292 LADSYSLDQRIFIgGDACHTHSPKAGQGMNAGFHDALNLA 331
Cdd:PRK06185 277 RLRRWHRPGLLCI-GDAAHAMSPVGGVGINLAIQDAVAAA 315
|
|
| PRK08849 |
PRK08849 |
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional |
6-376 |
8.66e-08 |
|
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
Pssm-ID: 181564 [Multi-domain] Cd Length: 384 Bit Score: 54.78 E-value: 8.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNR-----------DVptrtgRADGIQPRSVEILRNLGVKKQLVAHTSARL 74
Cdd:PRK08849 4 YDIAVVGGGMVGAATALGFAKQGRSVAVIEGGepkafepsqpmDI-----RVSAISQTSVDLLESLGAWSSIVAMRVCPY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 75 YNVAFWDpdpnsegiHrtsnwPSCPptigarypftltihqgiiERVFLDEMS--KCGTIVERPSTIVGFLHD---KENST 149
Cdd:PRK08849 79 KRLETWE--------H-----PECR------------------TRFHSDELNldQLGYIVENRLIQLGLWQQfaqYPNLT 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 150 YPVSVTLKSLDTNVE---------RTVRTKYLIGGEGTRSFIREQLGIKmqrkgpISAvWavmdgvvrtnfpDIRKKCti 220
Cdd:PRK08849 128 LMCPEKLADLEFSAEgnrvtlesgAEIEAKWVIGADGANSQVRQLAGIG------ITA-W------------DYRQHC-- 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 221 hshsgsvMVIPRENNLVR--LYTQISSPDDPD-------------W--DPKR----TATIQQAQDSIIKALKPYDITWDM 279
Cdd:PRK08849 187 -------MLINVETEQPQqdITWQQFTPSGPRsflplcgnqgslvWydSPKRikqlSAMNPEQLRSEILRHFPAELGEIK 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 280 VDWYSTYPIGQGLADSYSlDQRIFIGGDACHTHSPKAGQGMNAGFHDALNLawkIHAVE-AGFADRSILESYEAERRyiA 358
Cdd:PRK08849 260 VLQHGSFPLTRRHAQQYV-KNNCVLLGDAAHTINPLAGQGVNLGFKDVDVL---LAETEkQGVLNDASFARYERRRR--P 333
|
410 420
....*....|....*....|.
gi 315045818 359 QQLL---GFDAKYtKLFSQRL 376
Cdd:PRK08849 334 DNLLmqtGMDLFY-KTFSNSL 353
|
|
| PRK07045 |
PRK07045 |
putative monooxygenase; Reviewed |
1-364 |
1.73e-07 |
|
putative monooxygenase; Reviewed
Pssm-ID: 136171 [Multi-domain] Cd Length: 388 Bit Score: 53.76 E-value: 1.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 1 MREEVYDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQLVAHTSARLYNV-AF 79
Cdd:PRK07045 1 MKNNPVDVLINGSGIAGVALAHLLGARGHSVTVVERAARNRAQNGADLLKPSGIGVVRAMGLLDDVFAAGGLRRDAMrLY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 80 WDPDPNSEGIHRTSNwpscpptigARYPFTLtIHQGIIERVFLDEMSKCGTIVERPSTIVGFLHDKENSTypvsvtLKSL 159
Cdd:PRK07045 81 HDKELIASLDYRSAS---------ALGYFIL-IPCEQLRRLLLAKLDGLPNVRLRFETSIERIERDADGT------VTSV 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 160 DTNVERTVRTKYLIGGEGTRSFIREQ-LGIKMQR---KGPIS-AVWAVMDGVVRTNfpdirkKCTIHSHSGSVMVIPREN 234
Cdd:PRK07045 145 TLSDGERVAPTVLVGADGARSMIRDDvLRMPAERvpyATPMAfGTIALTDSVRECN------RLYVDSNQGLAYFYPIGD 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 235 NLVRLYTQISSPDDPDW--DPKRTATIQQAQ----DSIIKALKPYDITWDmvdwYSTYPIGQGLADSYSLDQRIFIGgDA 308
Cdd:PRK07045 219 QATRLVVSFPADEMQGYlaDTTRTKLLARLNefvgDESADAMAAIGAGTA----FPLIPLGRMNLDRYHKRNVVLLG-DA 293
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 315045818 309 CHTHSPKAGQGMNAGFHDALNLAWKIH-AVEAGFADRSILESYEAERRYIAQQLLGF 364
Cdd:PRK07045 294 AHSIHPITGQGMNLAIEDAGELGACLDlHLSGQIALADALERFERIRRPVNEAVISY 350
|
|
| GG-red-SF |
TIGR02032 |
geranylgeranyl reductase family; This model represents a subfamily which includes ... |
6-239 |
3.24e-07 |
|
geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]
Pssm-ID: 273936 [Multi-domain] Cd Length: 295 Bit Score: 52.32 E-value: 3.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNVKHIDNRDVPTRTGRADGIQPRSVEILRNLGVKKQLVAHTsARLYNvafwdpdPN 85
Cdd:TIGR02032 1 YDVVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPRYKPCGGALSPRALEELDLPGELIVNLVRG-ARFFS-------PN 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 86 SEGIHRTSnwpscpPTIGArypftltihqGIIERVFLDEM-------SKCGTIVERPSTIVGFLHDKENSTYpvsvtlks 158
Cdd:TIGR02032 73 GDSVEIPI------ETELA----------YVIDRDAFDEQlaeraqeAGAELRLGTRVLDVEIHDDRVVVIV-------- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 159 lDTnVERTVRTKYLIGGEGTRSFIREQLGikMQRKGPISAVwAVMDGVVRTNFPDIRKKCTIHSHSGSVM-----VIPRE 233
Cdd:TIGR02032 129 -RG-SEGTVTAKIVIGADGSRSIVAKKLG--LKKEPREYGV-AARAEVEMPDEEVDEDFVEVYIDRGIVPggygwVFPKG 203
|
....*.
gi 315045818 234 NNLVRL 239
Cdd:TIGR02032 204 DGTANV 209
|
|
| PRK07333 |
PRK07333 |
ubiquinone biosynthesis hydroxylase; |
6-356 |
1.30e-06 |
|
ubiquinone biosynthesis hydroxylase;
Pssm-ID: 180935 [Multi-domain] Cd Length: 403 Bit Score: 51.13 E-value: 1.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWG--YNVKHIDN--RDVPTRTGRADGIQPRSVEILRNLGVkkqlvahtsarlynvafWD 81
Cdd:PRK07333 2 CDVVIAGGGYVGLALAVALKQAAphLPVTVVDAapAGAWSRDPRASAIAAAARRMLEALGV-----------------WD 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 82 P-DPNSEGIHR---TSNWPSCP--PT-------IGARYPFTLTIHQgiieRVFLDEMSK-CGT--IVERPSTIVGFLHDK 145
Cdd:PRK07333 65 EiAPEAQPITDmviTDSRTSDPvrPVfltfegeVEPGEPFAHMVEN----RVLINALRKrAEAlgIDLREATSVTDFETR 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 146 ENStypVSVTLksldtNVERTVRTKYLIGGEGTRSFIREQLGIKmqrkgpiSAVWAV-MDGVVrtnfpdirkkCTI-H-- 221
Cdd:PRK07333 141 DEG---VTVTL-----SDGSVLEARLLVAADGARSKLRELAGIK-------TVGWDYgQSGIV----------CTVeHer 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 222 SH----------SGSVMVIPRENN---LVrlytqisspddpdWDpKRTATIQQ---AQDSIIKA-------LKPYDITWd 278
Cdd:PRK07333 196 PHggraeehflpAGPFAILPLKGNrssLV-------------WT-ERTADAERlvaLDDLVFEAeleqrfgHRLGELKV- 260
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 279 mVDWYSTYPIGQGLADSYsLDQRIFIGGDACHTHSPKAGQGMNAGFHDALNLAWKIhaVEAG-----FADRSILESYEAE 353
Cdd:PRK07333 261 -LGKRRAFPLGLTLARSF-VAPRFALVGDAAHGIHPIAGQGLNLGLKDVAALAEVV--VEAArlgldIGSLDVLERYQRW 336
|
...
gi 315045818 354 RRY 356
Cdd:PRK07333 337 RRF 339
|
|
| PRK07494 |
PRK07494 |
UbiH/UbiF family hydroxylase; |
1-192 |
6.08e-06 |
|
UbiH/UbiF family hydroxylase;
Pssm-ID: 181001 [Multi-domain] Cd Length: 388 Bit Score: 48.75 E-value: 6.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 1 MREEVYDIVIVGAGPFGLFLSLCLSRWGYNVKHIDnRDVPTRTGRADGIQPRSVEILRNLGVKKQLVAHTSA----RLyn 76
Cdd:PRK07494 3 MEKEHTDIAVIGGGPAGLAAAIALARAGASVALVA-PEPPYADLRTTALLGPSIRFLERLGLWARLAPHAAPlqsmRI-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 77 vafwdpdpnsegIHRTSNWPSCPPT------IGARyPFTLTIHQgiieRVFLDEMSKCGT---IVERPSTIVGFLHDKEN 147
Cdd:PRK07494 80 ------------VDATGRLIRAPEVrfraaeIGED-AFGYNIPN----WLLNRALEARVAelpNITRFGDEAESVRPRED 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 315045818 148 StypVSVTLKSldtnvERTVRTKYLIGGEGTRSFIREQLGIKMQR 192
Cdd:PRK07494 143 E---VTVTLAD-----GTTLSARLVVGADGRNSPVREAAGIGVRT 179
|
|
| PRK05732 |
PRK05732 |
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated |
152-377 |
3.45e-05 |
|
2-octaprenyl-6-methoxyphenyl hydroxylase; Validated
Pssm-ID: 235584 [Multi-domain] Cd Length: 395 Bit Score: 46.39 E-value: 3.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 152 VSVTLKSldtnvERTVRTKYLIGGEGTRSFIREQLGIKMQRKgPISAVwAVMDGVVRTNFPDIR--KKCTIHshsGSVMV 229
Cdd:PRK05732 146 VRVTLDD-----GETLTGRLLVAADGSHSALREALGIDWQQH-PYEQV-AVIANVTTSEAHQGRafERFTEH---GPLAL 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 230 IPRENN---LV-----RLYTQISSPDDPDWdpkrtatIQQAQDS-------IIKALKpyditwdmvdwYSTYPIGQGLAD 294
Cdd:PRK05732 216 LPMSDGrcsLVwchplEDAEEVLSWSDAQF-------LAELQQAfgwrlgrITHAGK-----------RSAYPLALVTAA 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 295 SySLDQRIFIGGDACHTHSPKAGQGMNAGFHDALNLAWKIHAVEAGFAD---RSILESYEAERRYIAQQLLGFDAKYTKL 371
Cdd:PRK05732 278 Q-QISHRLALVGNAAQTLHPIAGQGFNLGLRDVMSLAETLTQALARGEDigdYAVLQRYQQRRQQDREATIGFTDGLVRL 356
|
....*.
gi 315045818 372 FSQRLS 377
Cdd:PRK05732 357 FANRWA 362
|
|
| PRK05714 |
PRK05714 |
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional |
287-354 |
3.72e-05 |
|
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
Pssm-ID: 168201 [Multi-domain] Cd Length: 405 Bit Score: 46.36 E-value: 3.72e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 315045818 287 PIGQGLADSYsLDQRIFIGGDACHTHSPKAGQGMNAGFHDALNLAWKI-HAVEAG--FADRSILESYEAER 354
Cdd:PRK05714 273 PLRQRHAKRY-VEPGLALIGDAAHTIHPLAGQGVNLGFLDAAVLAEVLlHAAERGerLADVRVLSRFERRR 342
|
|
| PRK08850 |
PRK08850 |
2-octaprenyl-6-methoxyphenol hydroxylase; Validated |
300-373 |
5.78e-05 |
|
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
Pssm-ID: 236341 [Multi-domain] Cd Length: 405 Bit Score: 45.92 E-value: 5.78e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 315045818 300 QRIFIGGDACHTHSPKAGQGMNAGFHDALNLAWKIHAVEAGFAD---RSILESYEAERRYIAQQLLGFDAKYTKLFS 373
Cdd:PRK08850 282 ERVALVGDAAHTIHPLAGQGVNLGLLDAASLAQEILALWQQGRDiglKRNLRGYERWRKAEAAKMIAAMQGFRDLFS 358
|
|
| COG2509 |
COG2509 |
FAD-dependent dehydrogenase [General function prediction only]; |
6-49 |
7.97e-04 |
|
FAD-dependent dehydrogenase [General function prediction only];
Pssm-ID: 441999 [Multi-domain] Cd Length: 466 Bit Score: 42.41 E-value: 7.97e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNV------KHIDNRDVPTRTGRADGI 49
Cdd:COG2509 31 YDVVIVGAGPAGLFAALELAEAGLKPlvlergKDVEERTCPVAEFWRKGK 80
|
|
| ubiF |
PRK08020 |
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed |
306-376 |
1.65e-03 |
|
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
Pssm-ID: 181199 [Multi-domain] Cd Length: 391 Bit Score: 41.12 E-value: 1.65e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 315045818 306 GDACHTHSPKAGQGMNAGFHD--ALnLAWKIHAVEAG--FADRSILESYEAERRyiAQQLL---GFDAKYTKlFSQRL 376
Cdd:PRK08020 287 GDAAHTINPLAGQGVNLGYRDvdAL-LDVLVNARSYGeaWASEAVLKRYQRRRM--ADNLLmqsGMDLFYAG-FSNNL 360
|
|
| PRK09126 |
PRK09126 |
FAD-dependent hydroxylase; |
6-188 |
1.76e-03 |
|
FAD-dependent hydroxylase;
Pssm-ID: 236385 [Multi-domain] Cd Length: 392 Bit Score: 41.08 E-value: 1.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 6 YDIVIVGAGPFGLFLSLCLSRWGYNVKHIDN--RDV---PTRTGRADGIQPRSVEILRNLGVKKQLVAHTSARLYNVAFW 80
Cdd:PRK09126 4 SDIVVVGAGPAGLSFARSLAGSGLKVTLIERqpLAAladPAFDGREIALTHASREILQRLGAWDRIPEDEISPLRDAKVL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 81 DPDPNsegihrtsnwpscpptigarYPFTLTIHQG------------IIERVFLDEMSKCGTIVERPSTIVGFLHDKENS 148
Cdd:PRK09126 84 NGRSP--------------------FALTFDARGRgadalgylvpnhLIRRAAYEAVSQQDGIELLTGTRVTAVRTDDDG 143
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 315045818 149 typVSVTLKSldtnvERTVRTKYLIGGEGTRSFIREQLGI 188
Cdd:PRK09126 144 ---AQVTLAN-----GRRLTARLLVAADSRFSATRRQLGI 175
|
|
| PRK08773 |
PRK08773 |
UbiH/UbiF family hydroxylase; |
286-373 |
3.72e-03 |
|
UbiH/UbiF family hydroxylase;
Pssm-ID: 181552 [Multi-domain] Cd Length: 392 Bit Score: 40.23 E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 315045818 286 YPIGQGLADSYSLDqRIFIGGDACHTHSPKAGQGMNAGFHDALNLAWKIHAVEAGFADRSI---LESYEAERR---YIAQ 359
Cdd:PRK08773 269 FPLRRQLVQQYVSG-RVLTLGDAAHVVHPLAGQGVNLGLRDVAALQQLVRQAHARRADWAAphrLQRWARTRRsdnTVAA 347
|
90
....*....|....
gi 315045818 360 qlLGFDAkYTKLFS 373
Cdd:PRK08773 348 --YGFDA-INRVFS 358
|
|
| PRK08013 |
PRK08013 |
oxidoreductase; Provisional |
301-331 |
5.81e-03 |
|
oxidoreductase; Provisional
Pssm-ID: 236139 [Multi-domain] Cd Length: 400 Bit Score: 39.26 E-value: 5.81e-03
10 20 30
....*....|....*....|....*....|.
gi 315045818 301 RIFIGGDACHTHSPKAGQGMNAGFHDALNLA 331
Cdd:PRK08013 283 RLALVGDAAHTIHPLAGQGVNLGFMDAAELI 313
|
|
| |
