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Conserved domains on  [gi|167523529|ref|XP_001746101|]
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uncharacterized protein MONBRDRAFT_25774 [Monosiga brevicollis MX1]

Protein Classification

pectinacetylesterase family protein( domain architecture ID 10505531)

pectinacetylesterase (PAE) family protein such as Arabidopsis thaliana pectin acetylesterase, which hydrolyzes acetyl esters in homogalacturonan regions of pectin, and human palmitoleoyl-protein carboxylesterase NOTUM, which acts as a key negative regulator of the Wnt signaling pathway

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PAE pfam03283
Pectinacetylesterase;
16-353 3.30e-123

Pectinacetylesterase;


:

Pssm-ID: 460874  Cd Length: 345  Bit Score: 358.84  E-value: 3.30e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529   16 NADVPLTLLDKYPN--ARCMDGTPGGYYFQPSSnASASTKWVISLEGGGECATEDSCKSKLNTSLGSTDHRPKSIGSLGF 93
Cdd:pfam03283   6 GLDVPLTLVKNAVAkgAVCLDGSPPGYHFDRGF-GSGANNWLIHLEGGGWCNNLESCLSRKKTRLGSSKYMEKQISFSGI 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529   94 LGTDDcNENPVMCQWNRVEVVYCSQDLHSGQRaQPSDESWGIIFAGKLIVDAIIEDLEAnHGLTEATEIILSGDSAGGLG 173
Cdd:pfam03283  85 LSNNQ-SENPDFYNWNRVKIRYCDGASFTGDV-EPVDPATNLYFRGQRIWQAIIEDLLA-KGMKNAKNALLSGCSAGGLA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529  174 TWYHLNDLVDRYPQ-ASVYNVPIAGFYFPAYPYTGPNHTQSGLADFraeawpghVTL--WQSHMDQDCQRDMpvnDTWKC 250
Cdd:pfam03283 162 AILHCDYFRDLLPAnAKVKCLSDAGFFLDAKDISGTRHIRSFYSGV--------VTLqgSAKNLPESCTSRL---NPWKC 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529  251 MLANFSYPYMRAPIFIVEAQTDE--VVTTGHDWLPA-NDIYQ--PPEQAYLAEWAANMTQGLQRAANSHRDGVFNAACFI 325
Cdd:pfam03283 231 FFPQYVIPYIKTPLFILNSAYDSwqIQNILGSWCNCkLDIQNcsPSQLQFLQGFRSEFLNALKGFGNSPNNGMFINSCFA 310

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 167523529  326 H-------TTFTNSKPRINGLTYHQAMLQWLAGES 353
Cdd:pfam03283 311 HcqsesqdTWFADDSPRISNKTIAKAVGDWYFDRS 345
 
Name Accession Description Interval E-value
PAE pfam03283
Pectinacetylesterase;
16-353 3.30e-123

Pectinacetylesterase;


Pssm-ID: 460874  Cd Length: 345  Bit Score: 358.84  E-value: 3.30e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529   16 NADVPLTLLDKYPN--ARCMDGTPGGYYFQPSSnASASTKWVISLEGGGECATEDSCKSKLNTSLGSTDHRPKSIGSLGF 93
Cdd:pfam03283   6 GLDVPLTLVKNAVAkgAVCLDGSPPGYHFDRGF-GSGANNWLIHLEGGGWCNNLESCLSRKKTRLGSSKYMEKQISFSGI 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529   94 LGTDDcNENPVMCQWNRVEVVYCSQDLHSGQRaQPSDESWGIIFAGKLIVDAIIEDLEAnHGLTEATEIILSGDSAGGLG 173
Cdd:pfam03283  85 LSNNQ-SENPDFYNWNRVKIRYCDGASFTGDV-EPVDPATNLYFRGQRIWQAIIEDLLA-KGMKNAKNALLSGCSAGGLA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529  174 TWYHLNDLVDRYPQ-ASVYNVPIAGFYFPAYPYTGPNHTQSGLADFraeawpghVTL--WQSHMDQDCQRDMpvnDTWKC 250
Cdd:pfam03283 162 AILHCDYFRDLLPAnAKVKCLSDAGFFLDAKDISGTRHIRSFYSGV--------VTLqgSAKNLPESCTSRL---NPWKC 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529  251 MLANFSYPYMRAPIFIVEAQTDE--VVTTGHDWLPA-NDIYQ--PPEQAYLAEWAANMTQGLQRAANSHRDGVFNAACFI 325
Cdd:pfam03283 231 FFPQYVIPYIKTPLFILNSAYDSwqIQNILGSWCNCkLDIQNcsPSQLQFLQGFRSEFLNALKGFGNSPNNGMFINSCFA 310

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 167523529  326 H-------TTFTNSKPRINGLTYHQAMLQWLAGES 353
Cdd:pfam03283 311 HcqsesqdTWFADDSPRISNKTIAKAVGDWYFDRS 345
 
Name Accession Description Interval E-value
PAE pfam03283
Pectinacetylesterase;
16-353 3.30e-123

Pectinacetylesterase;


Pssm-ID: 460874  Cd Length: 345  Bit Score: 358.84  E-value: 3.30e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529   16 NADVPLTLLDKYPN--ARCMDGTPGGYYFQPSSnASASTKWVISLEGGGECATEDSCKSKLNTSLGSTDHRPKSIGSLGF 93
Cdd:pfam03283   6 GLDVPLTLVKNAVAkgAVCLDGSPPGYHFDRGF-GSGANNWLIHLEGGGWCNNLESCLSRKKTRLGSSKYMEKQISFSGI 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529   94 LGTDDcNENPVMCQWNRVEVVYCSQDLHSGQRaQPSDESWGIIFAGKLIVDAIIEDLEAnHGLTEATEIILSGDSAGGLG 173
Cdd:pfam03283  85 LSNNQ-SENPDFYNWNRVKIRYCDGASFTGDV-EPVDPATNLYFRGQRIWQAIIEDLLA-KGMKNAKNALLSGCSAGGLA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529  174 TWYHLNDLVDRYPQ-ASVYNVPIAGFYFPAYPYTGPNHTQSGLADFraeawpghVTL--WQSHMDQDCQRDMpvnDTWKC 250
Cdd:pfam03283 162 AILHCDYFRDLLPAnAKVKCLSDAGFFLDAKDISGTRHIRSFYSGV--------VTLqgSAKNLPESCTSRL---NPWKC 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 167523529  251 MLANFSYPYMRAPIFIVEAQTDE--VVTTGHDWLPA-NDIYQ--PPEQAYLAEWAANMTQGLQRAANSHRDGVFNAACFI 325
Cdd:pfam03283 231 FFPQYVIPYIKTPLFILNSAYDSwqIQNILGSWCNCkLDIQNcsPSQLQFLQGFRSEFLNALKGFGNSPNNGMFINSCFA 310

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 167523529  326 H-------TTFTNSKPRINGLTYHQAMLQWLAGES 353
Cdd:pfam03283 311 HcqsesqdTWFADDSPRISNKTIAKAVGDWYFDRS 345
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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