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Conserved domains on  [gi|1622839711|ref|XP_001115911|]
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leucine-rich repeat neuronal protein 4 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
76-263 1.25e-19

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 91.92  E-value: 1.25e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  76 LRSLNASHNLLRALSAsELGHLEQLRVLTLSHNRIAELRWGPGGPAGLHTLDLNYNQLAALTPCAGPaLSSLRVLALAGN 155
Cdd:COG4886   115 LESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGN-LTNLKELDLSNN 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 156 PLQALqPRAFACFPALQLLNLSCTALGRgaqggiaeaafAGEDGAPLATLEVLDLSGTFLQRVEsgWIRDLPKLTSLYLR 235
Cdd:COG4886   193 QITDL-PEPLGNLTNLEELDLSGNQLTD-----------LPEPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLS 258

                         170       180
                  ....*....|....*....|....*...
gi 1622839711 236 KMpRLTTLeGDIFKMTpNLQQLDCQDSP 263
Cdd:COG4886   259 NN-QLTDL-PPLANLT-NLKTLDLSNNQ 283
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 578-674 2.67e-13

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 65.98  E-value: 2.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 578 PDPPR-LQgVTETTDTSALVHWCAP---NSVVHGYQIRYSVEGwAGNQSVVGVIYATARQHPLYGLSPGTTYRVCVLAAN 653
Cdd:cd00063     1 PSPPTnLR-VTDVTSTSVTLSWTPPeddGGPITGYVVEYREKG-SGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90       100
                  ....*....|....*....|.
gi 1622839711 654 RAGLSQPrssgwrSPCAAFTT 674
Cdd:cd00063    79 GGGESPP------SESVTVTT 93
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
76-263 1.25e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 91.92  E-value: 1.25e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  76 LRSLNASHNLLRALSAsELGHLEQLRVLTLSHNRIAELRWGPGGPAGLHTLDLNYNQLAALTPCAGPaLSSLRVLALAGN 155
Cdd:COG4886   115 LESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGN-LTNLKELDLSNN 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 156 PLQALqPRAFACFPALQLLNLSCTALGRgaqggiaeaafAGEDGAPLATLEVLDLSGTFLQRVEsgWIRDLPKLTSLYLR 235
Cdd:COG4886   193 QITDL-PEPLGNLTNLEELDLSGNQLTD-----------LPEPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLS 258

                         170       180
                  ....*....|....*....|....*...
gi 1622839711 236 KMpRLTTLeGDIFKMTpNLQQLDCQDSP 263
Cdd:COG4886   259 NN-QLTDL-PPLANLT-NLKTLDLSNNQ 283
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 578-674 2.67e-13

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 65.98  E-value: 2.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 578 PDPPR-LQgVTETTDTSALVHWCAP---NSVVHGYQIRYSVEGwAGNQSVVGVIYATARQHPLYGLSPGTTYRVCVLAAN 653
Cdd:cd00063     1 PSPPTnLR-VTDVTSTSVTLSWTPPeddGGPITGYVVEYREKG-SGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90       100
                  ....*....|....*....|.
gi 1622839711 654 RAGLSQPrssgwrSPCAAFTT 674
Cdd:cd00063    79 GGGESPP------SESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 578-658 7.20e-12

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 61.86  E-value: 7.20e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  578 PDPPRLQGVTETTDTSALVHWCAPNS-VVHGYQIRYSVEGWAGNQSVVGVIY-ATARQHPLYGLSPGTTYRVCVLAANRA 655
Cdd:smart00060   1 PSPPSNLRVTDVTSTSVTLSWEPPPDdGITGYIVGYRVEYREEGSEWKEVNVtPSSTSYTLTGLKPGTEYEFRVRAVNGA 80


                   ...
gi 1622839711  656 GLS 658
Cdd:smart00060  81 GEG 83
fn3 pfam00041
Fibronectin type III domain;
579-660 2.65e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 60.12  E-value: 2.65e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 579 DPPRLQGVTETTDTSALVHWCAP---NSVVHGYQIRYSVEGwAGNQSVVGVIYATARQHPLYGLSPGTTYRVCVLAANRA 655
Cdd:pfam00041   1 SAPSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKN-SGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79


                  ....*
gi 1622839711 656 GLSQP 660
Cdd:pfam00041  80 GEGPP 84
LRR_8 pfam13855
Leucine rich repeat;
122-177 3.73e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.22  E-value: 3.73e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622839711 122 GLHTLDLNYNQLAALTPCAGPALSSLRVLALAGNPLQALQPRAFACFPALQLLNLS 177
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLS 57
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 64-212 9.07e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 53.25  E-value: 9.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  64 NLERLPG--CLPRtLRSLNASHNLLRALSasELGHLEQLRVLTLSHNRIAELRwGPGGPAGLHTLDLNYNQLAA---LT- 137
Cdd:cd21340    35 KITKIENleFLTN-LTHLYLQNNQIEKIE--NLENLVNLKKLYLGGNRISVVE-GLENLTNLEELHIENQRLPPgekLTf 110

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622839711 138 -PCAGPALS-SLRVLALAGNPLQALQPraFACFPALQLLNLSCTALGRGAQggIAEAAFAgedgapLATLEVLDLSG 212
Cdd:cd21340   111 dPRSLAALSnSLRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEE--LLDLLSS------WPSLRELDLTG 177
PLN03150 PLN03150
hypothetical protein; Provisional
 86-164 2.39e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.42  E-value: 2.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  86 LRALSASELGHLEQLRVLTLSHNRI-AELRWGPGGPAGLHTLDLNYNQLAALTPCAGPALSSLRVLALAGNPLQALQPRA 164
Cdd:PLN03150  430 LRGFIPNDISKLRHLQSINLSGNSIrGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAA 509
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
76-263 1.25e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 91.92  E-value: 1.25e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  76 LRSLNASHNLLRALSAsELGHLEQLRVLTLSHNRIAELRWGPGGPAGLHTLDLNYNQLAALTPCAGPaLSSLRVLALAGN 155
Cdd:COG4886   115 LESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGN-LTNLKELDLSNN 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 156 PLQALqPRAFACFPALQLLNLSCTALGRgaqggiaeaafAGEDGAPLATLEVLDLSGTFLQRVEsgWIRDLPKLTSLYLR 235
Cdd:COG4886   193 QITDL-PEPLGNLTNLEELDLSGNQLTD-----------LPEPLANLTNLETLDLSNNQLTDLP--ELGNLTNLEELDLS 258

                         170       180
                  ....*....|....*....|....*...
gi 1622839711 236 KMpRLTTLeGDIFKMTpNLQQLDCQDSP 263
Cdd:COG4886   259 NN-QLTDL-PPLANLT-NLKTLDLSNNQ 283
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
76-313 5.49e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 89.99  E-value: 5.49e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  76 LRSLNASHNllralsaSELGHLEQLRVLTLSHNRIAELRWGPGGPAGLHTLDLNYNQLAALtPCAGPALSSLRVLALAGN 155
Cdd:COG4886    98 LTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNN 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 156 PLQALqPRAFACFPALQLLNLSCTALGRgaqggiAEAAFAGedgapLATLEVLDLSGTFLQRVeSGWIRDLPKLTSLYLR 235
Cdd:COG4886   170 QLTDL-PEELGNLTNLKELDLSNNQITD------LPEPLGN-----LTNLEELDLSGNQLTDL-PEPLANLTNLETLDLS 236

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622839711 236 KMpRLTTLegdifkmtPNLQQLdcqdspalasvathifqdtPHLQVLLFQNCNLSSFPPwTLDSSQILSINLFGNPLT 313
Cdd:COG4886   237 NN-QLTDL--------PELGNL-------------------TNLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQLT 285
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
62-324 5.32e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 77.67  E-value: 5.32e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  62 NRNLERLPGCLPR--TLRSLNASHNLLRALSaSELGHLEQLRVLTLSHNRIAELRWGPGGPAGLHTLDLNYNQLAALtPC 139
Cdd:COG4886   145 NNQLTDLPEPLGNltNLKSLDLSNNQLTDLP-EELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDL-PE 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 140 AGPALSSLRVLALAGNPLQALqpRAFACFPALQLLNLSCTALgrgaqGGIAEAafagedgAPLATLEVLDLSGTflqrve 219
Cdd:COG4886   223 PLANLTNLETLDLSNNQLTDL--PELGNLTNLEELDLSNNQL-----TDLPPL-------ANLTNLKTLDLSNN------ 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 220 sgwirdlpKLTSLYLRKMPRLTTLEGDIFKMTPNLQQLDCQDSPALASVATHIFQDTPHLQVLLFQNCNLSSFPPWTLDS 299
Cdd:COG4886   283 --------QLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLL 354

                         250       260
                  ....*....|....*....|....*
gi 1622839711 300 SQILSINLFGNPLTCSCDLSWLLMD 324
Cdd:COG4886   355 LLNLLSLLLTLLLTLGLLGLLEATL 379
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 578-674 2.67e-13

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 65.98  E-value: 2.67e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 578 PDPPR-LQgVTETTDTSALVHWCAP---NSVVHGYQIRYSVEGwAGNQSVVGVIYATARQHPLYGLSPGTTYRVCVLAAN 653
Cdd:cd00063     1 PSPPTnLR-VTDVTSTSVTLSWTPPeddGGPITGYVVEYREKG-SGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVN 78

                          90       100
                  ....*....|....*....|.
gi 1622839711 654 RAGLSQPrssgwrSPCAAFTT 674
Cdd:cd00063    79 GGGESPP------SESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 578-658 7.20e-12

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 61.86  E-value: 7.20e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  578 PDPPRLQGVTETTDTSALVHWCAPNS-VVHGYQIRYSVEGWAGNQSVVGVIY-ATARQHPLYGLSPGTTYRVCVLAANRA 655
Cdd:smart00060   1 PSPPSNLRVTDVTSTSVTLSWEPPPDdGITGYIVGYRVEYREEGSEWKEVNVtPSSTSYTLTGLKPGTEYEFRVRAVNGA 80


                   ...
gi 1622839711  656 GLS 658
Cdd:smart00060  81 GEG 83
fn3 pfam00041
Fibronectin type III domain;
579-660 2.65e-11

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 60.12  E-value: 2.65e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 579 DPPRLQGVTETTDTSALVHWCAP---NSVVHGYQIRYSVEGwAGNQSVVGVIYATARQHPLYGLSPGTTYRVCVLAANRA 655
Cdd:pfam00041   1 SAPSNLTVTDVTSTSLTVSWTPPpdgNGPITGYEVEYRPKN-SGEPWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGG 79


                  ....*
gi 1622839711 656 GLSQP 660
Cdd:pfam00041  80 GEGPP 84
LRR_8 pfam13855
Leucine rich repeat;
122-177 3.73e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 50.22  E-value: 3.73e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622839711 122 GLHTLDLNYNQLAALTPCAGPALSSLRVLALAGNPLQALQPRAFACFPALQLLNLS 177
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLS 57
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 64-212 9.07e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 53.25  E-value: 9.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  64 NLERLPG--CLPRtLRSLNASHNLLRALSasELGHLEQLRVLTLSHNRIAELRwGPGGPAGLHTLDLNYNQLAA---LT- 137
Cdd:cd21340    35 KITKIENleFLTN-LTHLYLQNNQIEKIE--NLENLVNLKKLYLGGNRISVVE-GLENLTNLEELHIENQRLPPgekLTf 110

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622839711 138 -PCAGPALS-SLRVLALAGNPLQALQPraFACFPALQLLNLSCTALGRGAQggIAEAAFAgedgapLATLEVLDLSG 212
Cdd:cd21340   111 dPRSLAALSnSLRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEE--LLDLLSS------WPSLRELDLTG 177
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 74-161 2.34e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 49.01  E-value: 2.34e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  74 RTLRSLNASHNLLRALSasELGHLEQLRVLTLSHNRIAELrwgpggpaglhtldlnyNQLAALTPCagpaLSSLRVLALA 153
Cdd:cd21340   120 NSLRVLNISGNNIDSLE--PLAPLRNLEQLDASNNQISDL-----------------EELLDLLSS----WPSLRELDLT 176


                  ....*...
gi 1622839711 154 GNPLQALQ 161
Cdd:cd21340   177 GNPVCKKP 184
LRR_8 pfam13855
Leucine rich repeat;
74-133 5.12e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.44  E-value: 5.12e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622839711  74 RTLRSLNASHNLLRALSASELGHLEQLRVLTLSHNRIAELRWGP-GGPAGLHTLDLNYNQL 133
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAfSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
169-235 6.23e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.05  E-value: 6.23e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622839711 169 PALQLLNLSCTALGrgaqgGIAEAAFAGedgapLATLEVLDLSGTFLQRVESGWIRDLPKLTSLYLR 235
Cdd:pfam13855   1 PNLRSLDLSNNRLT-----SLDDGAFKG-----LSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLS 57
LRR_8 pfam13855
Leucine rich repeat;
145-213 8.53e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.67  E-value: 8.53e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622839711 145 SSLRVLALAGNPLQALQPRAFACFPALQLLNLSCTALGRgaqggIAEAAFAGedgapLATLEVLDLSGT 213
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT-----LSPGAFSG-----LPSLRYLDLSGN 59
LRR_8 pfam13855
Leucine rich repeat;
99-157 1.18e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.28  E-value: 1.18e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  99 QLRVLTLSHNRIAELRWGP-GGPAGLHTLDLNYNQLAALTPCAGPALSSLRVLALAGNPL 157
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 86-164 2.39e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.42  E-value: 2.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  86 LRALSASELGHLEQLRVLTLSHNRI-AELRWGPGGPAGLHTLDLNYNQLAALTPCAGPALSSLRVLALAGNPLQALQPRA 164
Cdd:PLN03150  430 LRGFIPNDISKLRHLQSINLSGNSIrGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAA 509
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 123-315 9.74e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.96  E-value: 9.74e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 123 LHTLDLNYNQLAALT------PCAGPALSSLRVLALAGNPLQALQPRAFACF---PALQLLNLSCTALGRGAQGGIAEAA 193
Cdd:cd00116    53 LKELCLSLNETGRIPrglqslLQGLTKGCGLQELDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLGDRGLRLLAKGL 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 194 fagedGAPLATLEVLDLSGtflQRVESGWIRDLPKLtslyLRKMPRLTTLE--------------GDIFKMTPNLQQLDC 259
Cdd:cd00116   133 -----KDLPPALEKLVLGR---NRLEGASCEALAKA----LRANRDLKELNlanngigdagiralAEGLKANCNLEVLDL 200

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622839711 260 QDS---PALASVATHIFQDTPHLQVLLFQNCNLSSFPPWTLDSS------QILSINLFGNPLTCS 315
Cdd:cd00116   201 NNNgltDEGASALAETLASLKSLEVLNLGDNNLTDAGAAALASAllspniSLLTLSLSCNDITDD 265
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
62-168 2.31e-03

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 41.22  E-value: 2.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  62 NRNLERLPGCLPRTLRSLNASHNLLRALSASelgHLEQLRVLTLSHNRIAELrwgPGG-PAGLHTLDLNYNQLAALtPCA 140
Cdd:PRK15370  313 SNSLTALPETLPPGLKTLEAGENALTSLPAS---LPPELQVLDVSKNQITVL---PETlPPTITTLDVSRNALTNL-PEN 385

                          90       100
                  ....*....|....*....|....*...
gi 1622839711 141 GPAlsSLRVLALAGNPLQALqPRAFACF 168
Cdd:PRK15370  386 LPA--ALQIMQASRNNLVRL-PESLPHF 410
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 205-245 2.61e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 36.07  E-value: 2.61e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1622839711 205 LEVLDLSGTFLQRVESgwIRDLPKLTSLYLRKMPRLTTLEG 245
Cdd:pfam12799   3 LEVLDLSNNQITDIPP--LAKLPNLETLDLSGNNKITDLSD 41
Pur_ac_phosph_N pfam16656
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple ...
 589-674 2.82e-03

Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple acid phosphatase proteins.


Pssm-ID: 465220 [Multi-domain]  Cd Length: 93  Bit Score: 37.77  E-value: 2.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 589 TTDTSALVHWcAPNSVVHGYQIRYSVEGWAGNQSVVGVI--YATARQHPLY-------GLSPGTTYRVCVLAANRaglsq 659
Cdd:pfam16656  10 GDSTSMTVSW-VTPSAVTSPVVQYGTSSSALTSTATATSstYTTGDGGTGYihratltGLEPGTTYYYRVGDDNG----- 83

                          90
                  ....*....|....*
gi 1622839711 660 pRSSGWRSpcaaFTT 674
Cdd:pfam16656  84 -GWSEVYS----FTT 93
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 76-181 4.86e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.22  E-value: 4.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  76 LRSLNASHNLLRALSASELGHL-EQLRVLTLSHNRIAelrwGP---GGPAGLHTLDLNYNQLAALTPCAGPALSSLRVLA 151
Cdd:PLN00113   95 IQTINLSNNQLSGPIPDDIFTTsSSLRYLNLSNNNFT----GSiprGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLD 170

                          90       100       110
                  ....*....|....*....|....*....|
gi 1622839711 152 LAGNPLQALQPRAFACFPALQLLNLSCTAL 181
Cdd:PLN00113  171 LGGNVLVGKIPNSLTNLTSLEFLTLASNQL 200
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 75-310 8.18e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.83  E-value: 8.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711  75 TLRSLNASHNLLRALSASELGHLEQLRVLTLSHNRIAelrwGPGGPA-----GLHTLDLNYNQLAALTPCAGPALSSLRV 149
Cdd:PLN00113  237 SLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLS----GPIPPSifslqKLISLDLSDNSLSGEIPELVIQLQNLEI 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 150 LALAGNPLQALQPRAFACFPALQLLNLSCTALgrgaQGGIAeaafagEDGAPLATLEVLDLSGTFLQ-RVESGwIRDLPK 228
Cdd:PLN00113  313 LHLFSNNFTGKIPVALTSLPRLQVLQLWSNKF----SGEIP------KNLGKHNNLTVLDLSTNNLTgEIPEG-LCSSGN 381

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839711 229 LTSLYLRKmprlTTLEGDIFK---MTPNLQQLDCQDSpALASVATHIFQDTPHLQVLLFQNCNLS---SFPPWTLDSSQI 302
Cdd:PLN00113  382 LFKLILFS----NSLEGEIPKslgACRSLRRVRLQDN-SFSGELPSEFTKLPLVYFLDISNNNLQgriNSRKWDMPSLQM 456

                         250
                  ....*....|.
gi 1622839711 303 LSI---NLFGN 310
Cdd:PLN00113  457 LSLarnKFFGG 467
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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