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Conserved domains on  [gi|297295050|ref|XP_001104907|]
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ankyrin repeat domain-containing protein SOWAHA [Macaca mulatta]

Protein Classification

ankyrin repeat domain-containing protein( domain architecture ID 11429852)

ankyrin repeat domain-containing protein; ANK proteins mediate specific protein-protein interactions without necessarily recognizing specific primary sequences which allows for one ankyrin repeat domain to recognize and bind to a variety of intracellular substrates and may be involved in a wide array of functions

Gene Ontology:  GO:0005515
PubMed:  17176038
SCOP:  4000366

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
345-437 1.68e-17

Ankyrin repeat [Signal transduction mechanisms];


:

Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 83.08  E-value: 1.68e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 345 GFTALHWAAKSGDGEMALQLVEvarrsgAPVDVNARSHGGYTPLHLAALHGHEDAAVLLvVRLGAQVNVRDHSGRRAYHY 424
Cdd:COG0666  153 GNTPLHLAAANGNLEIVKLLLE------AGADVNARDNDGETPLHLAAENGHLEIVKLL-LEAGADVNAKDNDGKTALDL 225

                         90
                 ....*....|...
gi 297295050 425 LRPGSSYALRRLL 437
Cdd:COG0666  226 AAENGNLEIVKLL 238
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
91-190 1.02e-05

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK07994:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 647  Bit Score: 48.32  E-value: 1.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  91 APFGPQGAAAQPSKPTVVLPGDASAPGAPPLVPVPRQVEPPGDLGPLTETQDTPRGPASEPAQPAGERSADPPLPALela 170
Cdd:PRK07994 383 ATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAAASRARPVNSALERL--- 459

                         90       100
                 ....*....|....*....|
gi 297295050 171 qAPEGPSADAAPPPRASSEA 190
Cdd:PRK07994 460 -ASVRPAPSALEKAPAKKEA 478
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
345-437 1.68e-17

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 83.08  E-value: 1.68e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 345 GFTALHWAAKSGDGEMALQLVEvarrsgAPVDVNARSHGGYTPLHLAALHGHEDAAVLLvVRLGAQVNVRDHSGRRAYHY 424
Cdd:COG0666  153 GNTPLHLAAANGNLEIVKLLLE------AGADVNARDNDGETPLHLAAENGHLEIVKLL-LEAGADVNAKDNDGKTALDL 225

                         90
                 ....*....|...
gi 297295050 425 LRPGSSYALRRLL 437
Cdd:COG0666  226 AAENGNLEIVKLL 238
Ank_2 pfam12796
Ankyrin repeats (3 copies);
345-415 1.75e-11

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 60.51  E-value: 1.75e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 297295050  345 GFTALHWAAKSGDGEMALQLVEVArrsgapvDVNARSHGgYTPLHLAALHGHEDaAVLLVVRLGAQVNVRD 415
Cdd:pfam12796  30 GRTALHLAAKNGHLEIVKLLLEHA-------DVNLKDNG-RTALHYAARSGHLE-IVKLLLEKGADINVKD 91
PHA03095 PHA03095
ankyrin-like protein; Provisional
 331-419 1.03e-06

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 51.18  E-value: 1.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 331 LRDRGLAAKRDFMSGFTALHWAAKSGDGEMAL--QLVEvarrsgAPVDVNARSHGGYTPLHLAALHGHeDAAVLLVVRLG 408
Cdd:PHA03095 208 LIRAGCDPAATDMLGNTPLHSMATGSSCKRSLvlPLLI------AGISINARNRYGQTPLHYAAVFNN-PRACRRLIALG 280

                         90
                 ....*....|.
gi 297295050 409 AQVNVRDHSGR 419
Cdd:PHA03095 281 ADINAVSSDGN 291
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 91-190 1.02e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 48.32  E-value: 1.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  91 APFGPQGAAAQPSKPTVVLPGDASAPGAPPLVPVPRQVEPPGDLGPLTETQDTPRGPASEPAQPAGERSADPPLPALela 170
Cdd:PRK07994 383 ATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAAASRARPVNSALERL--- 459

                         90       100
                 ....*....|....*....|
gi 297295050 171 qAPEGPSADAAPPPRASSEA 190
Cdd:PRK07994 460 -ASVRPAPSALEKAPAKKEA 478
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 384-413 1.08e-03

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 36.41  E-value: 1.08e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 297295050   384 GYTPLHLAALHGHEDAAVLLvVRLGAQVNV 413
Cdd:smart00248   2 GRTPLHLAAENGNLEVVKLL-LDKGADINA 30
 
Name Accession Description Interval E-value
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
345-437 1.68e-17

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 83.08  E-value: 1.68e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 345 GFTALHWAAKSGDGEMALQLVEvarrsgAPVDVNARSHGGYTPLHLAALHGHEDAAVLLvVRLGAQVNVRDHSGRRAYHY 424
Cdd:COG0666  153 GNTPLHLAAANGNLEIVKLLLE------AGADVNARDNDGETPLHLAAENGHLEIVKLL-LEAGADVNAKDNDGKTALDL 225

                         90
                 ....*....|...
gi 297295050 425 LRPGSSYALRRLL 437
Cdd:COG0666  226 AAENGNLEIVKLL 238
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
344-424 3.41e-16

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 79.23  E-value: 3.41e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 344 SGFTALHWAAKSGDGEMALQLVEvarrSGApvDVNARSHGGYTPLHLAALHGHEDAAVLLvVRLGAQVNVRDHSGRRAYH 423
Cdd:COG0666  119 DGETPLHLAAYNGNLEIVKLLLE----AGA--DVNAQDNDGNTPLHLAAANGNLEIVKLL-LEAGADVNARDNDGETPLH 191


                 .
gi 297295050 424 Y 424
Cdd:COG0666  192 L 192
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
329-424 7.90e-16

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 78.07  E-value: 7.90e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 329 LLLRDRGLAAKRDFMSGFTALHWAAKSGDGEMALQLVEvarrsgAPVDVNARSHGGYTPLHLAALHGHEDAAVLLvVRLG 408
Cdd:COG0666   71 LLLLAAGADINAKDDGGNTLLHAAARNGDLEIVKLLLE------AGADVNARDKDGETPLHLAAYNGNLEIVKLL-LEAG 143

                         90
                 ....*....|....*.
gi 297295050 409 AQVNVRDHSGRRAYHY 424
Cdd:COG0666  144 ADVNAQDNDGNTPLHL 159
Ank_2 pfam12796
Ankyrin repeats (3 copies);
345-415 1.75e-11

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 60.51  E-value: 1.75e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 297295050  345 GFTALHWAAKSGDGEMALQLVEVArrsgapvDVNARSHGgYTPLHLAALHGHEDaAVLLVVRLGAQVNVRD 415
Cdd:pfam12796  30 GRTALHLAAKNGHLEIVKLLLEHA-------DVNLKDNG-RTALHYAARSGHLE-IVKLLLEKGADINVKD 91
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
345-443 3.11e-11

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 64.20  E-value: 3.11e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 345 GFTALHWAAKSGDGEMALQLVEvarrSGApvDVNARSHGGYTPLHLAALHGHEDAAVLLvVRLGAQVNVRDHSGRRAYHY 424
Cdd:COG0666  186 GETPLHLAAENGHLEIVKLLLE----AGA--DVNAKDNDGKTALDLAAENGNLEIVKLL-LEAGADLNAKDKDGLTALLL 258

                         90
                 ....*....|....*....
gi 297295050 425 LRPGSSYALRRLLGDPGLR 443
Cdd:COG0666  259 AAAAGAALIVKLLLLALLL 277
Ank_2 pfam12796
Ankyrin repeats (3 copies);
349-424 1.11e-09

Ankyrin repeats (3 copies);


Pssm-ID: 463710 [Multi-domain]  Cd Length: 91  Bit Score: 55.51  E-value: 1.11e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 297295050  349 LHWAAKSGDGEMALQLVEvarrsgAPVDVNARSHGGYTPLHLAALHGHEDAAVLLVVRlgAQVNVRDHsGRRAYHY 424
Cdd:pfam12796   1 LHLAAKNGNLELVKLLLE------NGADANLQDKNGRTALHLAAKNGHLEIVKLLLEH--ADVNLKDN-GRTALHY 67
Ank_4 pfam13637
Ankyrin repeats (many copies);
347-404 1.49e-08

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 51.12  E-value: 1.49e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 297295050  347 TALHWAAKSGDgemaLQLVEVARRSGApvDVNARSHGGYTPLHLAALHGHEDAAVLLV 404
Cdd:pfam13637   3 TALHAAAASGH----LELLRLLLEKGA--DINAVDGNGETALHFAASNGNVEVLKLLL 54
ANKYR COG0666
Ankyrin repeat [Signal transduction mechanisms];
329-424 7.25e-07

Ankyrin repeat [Signal transduction mechanisms];


Pssm-ID: 440430 [Multi-domain]  Cd Length: 289  Bit Score: 51.11  E-value: 7.25e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 329 LLLRDRGLAAKRDFMSGFTALHWAAKSGDGEMALQLVEvarrsgAPVDVNARSHGGYTPLHLAALHGHEDAAVLLVvRLG 408
Cdd:COG0666   38 LLLLLALLALALADALGALLLLAAALAGDLLVALLLLA------AGADINAKDDGGNTLLHAAARNGDLEIVKLLL-EAG 110

                         90
                 ....*....|....*.
gi 297295050 409 AQVNVRDHSGRRAYHY 424
Cdd:COG0666  111 ADVNARDKDGETPLHL 126
PHA03095 PHA03095
ankyrin-like protein; Provisional
 331-419 1.03e-06

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 51.18  E-value: 1.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 331 LRDRGLAAKRDFMSGFTALHWAAKSGDGEMAL--QLVEvarrsgAPVDVNARSHGGYTPLHLAALHGHeDAAVLLVVRLG 408
Cdd:PHA03095 208 LIRAGCDPAATDMLGNTPLHSMATGSSCKRSLvlPLLI------AGISINARNRYGQTPLHYAAVFNN-PRACRRLIALG 280

                         90
                 ....*....|.
gi 297295050 409 AQVNVRDHSGR 419
Cdd:PHA03095 281 ADINAVSSDGN 291
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 91-190 1.02e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 48.32  E-value: 1.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  91 APFGPQGAAAQPSKPTVVLPGDASAPGAPPLVPVPRQVEPPGDLGPLTETQDTPRGPASEPAQPAGERSADPPLPALela 170
Cdd:PRK07994 383 ATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPAAASRARPVNSALERL--- 459

                         90       100
                 ....*....|....*....|
gi 297295050 171 qAPEGPSADAAPPPRASSEA 190
Cdd:PRK07994 460 -ASVRPAPSALEKAPAKKEA 478
PHA03095 PHA03095
ankyrin-like protein; Provisional
 372-426 3.79e-05

ankyrin-like protein; Provisional


Pssm-ID: 222980 [Multi-domain]  Cd Length: 471  Bit Score: 46.17  E-value: 3.79e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 297295050 372 GApvDVNARSHGGYTPLHLAALHGHEDAAVLLVVRLGAQVNVRDHSGRRAYH-YLR 426
Cdd:PHA03095  73 GA--DVNAPERCGFTPLHLYLYNATTLDVIKLLIKAGADVNAKDKVGRTPLHvYLS 126
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
91-190 5.07e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.38  E-value: 5.07e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  91 APFGPQGAAAQPSKPTVVLPGDASAPGAPPLVPVPRQVEPPGDLGP-LTETQDTPRGPASEPAQPAGERSADPPLPALE- 168
Cdd:PRK07003 431 APPATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSaSAPASDAPPDAAFEPAPRAAAPSAATPAAVPDa 510

                         90       100
                 ....*....|....*....|....*.
gi 297295050 169 ----LAQAPEGPSADAAPPPRASSEA 190
Cdd:PRK07003 511 rapaAASREDAPAAAAPPAPEARPPT 536
Ank_5 pfam13857
Ankyrin repeats (many copies);
374-424 5.95e-05

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 40.79  E-value: 5.95e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 297295050  374 PVDVNARSHGGYTPLHLAALHGHEDAAVLLVVRlGAQVNVRDHSGRRAYHY 424
Cdd:pfam13857   6 PIDLNRLDGEGYTPLHVAAKYGALEIVRVLLAY-GVDLNLKDEEGLTALDL 55
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
91-215 7.29e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.64  E-value: 7.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  91 APFGPQGAAAQPskPTVVLPGDASAPGAPPLVPVPRQVEPPGDLGPltetqdTPRGPASEPAQPAGERSADPPLPALELA 170
Cdd:PRK12323 380 APVAQPAPAAAA--PAAAAPAPAAPPAAPAAAPAAAAAARAVAAAP------ARRSPAPEALAAARQASARGPGGAPAPA 451

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 297295050 171 QAPEGPSADAAPPPRASSEAASPCSDPPDPEPGPGAAKGPSQQKP 215
Cdd:PRK12323 452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDP 496
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 95-193 9.61e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 45.09  E-value: 9.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  95 PQGAAAQPSKPTVVLPGDASAPGAPPLVPVPRQVEPPGDLGPlteTQDTPRGPASEPAQPAGERSADPPLPALELAQAPE 174
Cdd:PRK14951 393 PVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAP---AAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPE 469

                         90
                 ....*....|....*....
gi 297295050 175 GPSADAAPPPRASSEAASP 193
Cdd:PRK14951 470 PAVASAAPAPAAAPAAARL 488
Ank pfam00023
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 384-416 1.47e-04

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity.


Pssm-ID: 459634 [Multi-domain]  Cd Length: 34  Bit Score: 39.19  E-value: 1.47e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 297295050  384 GYTPLHLAALH-GHEDAAVLLvVRLGAQVNVRDH 416
Cdd:pfam00023   2 GNTPLHLAAGRrGNLEIVKLL-LSKGADVNARDK 34
PHA02874 PHA02874
ankyrin repeat protein; Provisional
 347-441 1.84e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165205 [Multi-domain]  Cd Length: 434  Bit Score: 44.18  E-value: 1.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 347 TALHWAAKSGDgemaLQLVEVARRSGApvDVNARSHGGYTPLHLAALHGHEDAAVLLVVRlGAQVNVRDHSGRRAYHYLR 426
Cdd:PHA02874 126 TFLHYAIKKGD----LESIKMLFEYGA--DVNIEDDNGCYPIHIAIKHNFFDIIKLLLEK-GAYANVKDNNGESPLHNAA 198

                         90
                 ....*....|....*
gi 297295050 427 PGSSYALRRLLGDPG 441
Cdd:PHA02874 199 EYGDYACIKLLIDHG 213
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 95-191 2.20e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 44.03  E-value: 2.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  95 PQGAAAQPSKPTVVLPGdaSAPGAPPLVPVPRQVEPPGdlgPLTETQDTPRGPASEPAQPAGERSADPPLPALELAQAPE 174
Cdd:PRK14950 366 PQPAKPTAAAPSPVRPT--PAPSTRPKAAAAANIPPKE---PVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAIPVDE 440

                         90
                 ....*....|....*..
gi 297295050 175 GPSADAAPPPRASSEAA 191
Cdd:PRK14950 441 KPKYTPPAPPKEEEKAL 457
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 93-235 3.99e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.16  E-value: 3.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  93 FGPQGAAAQPskptvvlPGDASAPGAPPLVPVPRQVEPPgdlgpltetqDTPRGPASEPAQPAGERSADPPLPALELAQA 172
Cdd:PRK14951 364 FKPAAAAEAA-------APAEKKTPARPEAAAPAAAPVA----------QAAAAPAPAAAPAAAASAPAAPPAAAPPAPV 426

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 297295050 173 PEGPSADAAPPPRASSEAASPCSDPPDPEPGPGAAKGPSQQ-KPCMLPVRCVPA---AATLRIRAEE 235
Cdd:PRK14951 427 AAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVApEPAVASAAPAPAaapAAARLTPTEE 493
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 94-193 4.37e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.05  E-value: 4.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  94 GPQGAAAQPSKPTVVLPGDASAPGAPPLVPVPRQVEPPGDLGPLTETQDTPRGPASEPAQPAGERSAD-----PPLPALE 168
Cdd:PRK07764 667 DGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAaddpvPLPPEPD 746

                         90       100
                 ....*....|....*....|....*
gi 297295050 169 LAQAPEGPSADAAPPPRASSEAASP 193
Cdd:PRK07764 747 DPPDPAGAPAQPPPPPAPAPAAAPA 771
PHA02876 PHA02876
ankyrin repeat protein; Provisional
 331-424 6.83e-04

ankyrin repeat protein; Provisional


Pssm-ID: 165207 [Multi-domain]  Cd Length: 682  Bit Score: 42.36  E-value: 6.83e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 331 LRDRGLAAKRDFMSGFTALHWAAKSG-DGEMALQLVEVarrsGApvDVNARSHGGYTPLHLAALHGHEDAAVLLVVRLGA 409
Cdd:PHA02876 293 LLERGADVNAKNIKGETPLYLMAKNGyDTENIRTLIML----GA--DVNAADRLYITPLHQASTLDRNKDIVITLLELGA 366

                         90
                 ....*....|....*
gi 297295050 410 QVNVRDHSGRRAYHY 424
Cdd:PHA02876 367 NVNARDYCDKTPIHY 381
Ank_4 pfam13637
Ankyrin repeats (many copies);
384-424 7.17e-04

Ankyrin repeats (many copies);


Pssm-ID: 372654 [Multi-domain]  Cd Length: 54  Bit Score: 37.64  E-value: 7.17e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 297295050  384 GYTPLHLAALHGHEDAAVLLvVRLGAQVNVRDHSGRRAYHY 424
Cdd:pfam13637   1 ELTALHAAAASGHLELLRLL-LEKGADINAVDGNGETALHF 40
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
90-252 9.88e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 9.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  90 PAPFGPQGAAAQPSKPTVVLPGDASAPGAPPLVPVPRQVeppgdlgpltETQDTPRGPASEPAQPAGERSADPPLPALEL 169
Cdd:PRK12323 397 PAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAA----------ARQASARGPGGAPAPAPAPAAAPAAAARPAA 466

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 170 AQAPEGPSADAAPPPRASSEAASPCSDPPDP----EPGPGAAKGPSQQKPCmlPVRCVPAAATLRIRAEEQGLRRQLSEE 245
Cdd:PRK12323 467 AGPRPVAAAAAAAPARAAPAAAPAPADDDPPpweeLPPEFASPAPAQPDAA--PAGWVAESIPDPATADPDDAFETLAPA 544


                 ....*..
gi 297295050 246 PSPRSSP 252
Cdd:PRK12323 545 PAAAPAP 551
ANK smart00248
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ...
 384-413 1.08e-03

ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure.


Pssm-ID: 197603 [Multi-domain]  Cd Length: 30  Bit Score: 36.41  E-value: 1.08e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 297295050   384 GYTPLHLAALHGHEDAAVLLvVRLGAQVNV 413
Cdd:smart00248   2 GRTPLHLAAENGNLEVVKLL-LDKGADINA 30
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 136-257 1.10e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 41.62  E-value: 1.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 136 PLTETQDTPRGPASEPAQPAGERSADPPLPALELAQAPEGPSADAAPPPRASSEAASPCSDPPDPEPGPGAAKGPSQQKP 215
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAV 445

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 297295050 216 CMLPVRCVPAA---ATLRIRAEEQGLRRQLSEEPSPRSSPLLLRR 257
Cdd:PRK14951 446 ALAPAPPAQAApetVAIPVRVAPEPAVASAAPAPAAAPAAARLTP 490
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
91-260 1.19e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.79  E-value: 1.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  91 APFGPQGAAAQPSKPTVVL-PGDASAPG-APPLVPVPRQVEPPGDLGPLTETQDTPRGPASEPAQPAGERSADPPLPALE 168
Cdd:PRK12323 424 ARRSPAPEALAAARQASARgPGGAPAPApAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELP 503

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 169 LAQAPEGPSADAAPPPRASSEAASPCSDPPDPEPGPGAAKGPSQQKPCMLPVRCVPAAATLRIRAEEQGLrrqlsEEPSP 248
Cdd:PRK12323 504 PEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGL-----PDMFD 578

                        170
                 ....*....|..
gi 297295050 249 RSSPLLLRRLSV 260
Cdd:PRK12323 579 GDWPALAARLPV 590
Ank_5 pfam13857
Ankyrin repeats (many copies);
345-391 1.83e-03

Ankyrin repeats (many copies);


Pssm-ID: 433530 [Multi-domain]  Cd Length: 56  Bit Score: 36.56  E-value: 1.83e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 297295050  345 GFTALHWAAKSGDGEMALQLVEvarrsgAPVDVNARSHGGYTPLHLA 391
Cdd:pfam13857  16 GYTPLHVAAKYGALEIVRVLLA------YGVDLNLKDEEGLTALDLA 56
PHA03247 PHA03247
large tegument protein UL36; Provisional
 95-181 2.43e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 2.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050   95 PQGAAAQPSKPTVVLPGDASAPGAPPLVPVPRQVEPPGDLGPLTETQDTPRGPASEPAQPAGERSADPPLPALELAQAPE 174
Cdd:PHA03247  405 TRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAEPGSDDGPAPPPERQPPAPATEPAPDDPDDATRKALDALRERRPPE 484


                  ....*..
gi 297295050  175 GPSADAA 181
Cdd:PHA03247  485 PPGADLA 491
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 46-184 2.74e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 2.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  46 GDPRGRAARRDRFKQFVNNVAVVKEldgVKFVVLRKKPRPPEPEPAPFGPQGAAAQPSKPTVV-LPGDASAPGAPPLVPV 124
Cdd:PRK07764 369 DDERGLLARLERLERRLGVAGGAGA---PAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAApQPAPAPAPAPAPPSPA 445

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050 125 PRQVEPPGDLGPLTETQDTPRGPASEPAQPAGERSADPPLPALELAQAPEGPSADAAPPP 184
Cdd:PRK07764 446 GNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAG 505
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
97-252 3.40e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 40.22  E-value: 3.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  97 GAAAQPSKPTVVLPGDASAPGAPPLVPVPRQVEPpgdlGPLTETQDTPRGPASEPAQPAGERSADPPLPALELAQAPegP 176
Cdd:PRK07003 384 GARAAAAVGASAVPAVTAVTGAAGAALAPKAAAA----AAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANAR--A 457

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 297295050 177 SADAAPPPRASSEAASPCSDPPDPE-PGPGAAKGPSQQKPCMLPVRCVPAAATLRIRAEEQGLRRQLSEEPSPRSSP 252
Cdd:PRK07003 458 SADSRCDERDAQPPADSGSASAPASdAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARP 534
PLN03192 PLN03192
Voltage-dependent potassium channel; Provisional
 384-421 3.68e-03

Voltage-dependent potassium channel; Provisional


Pssm-ID: 215625 [Multi-domain]  Cd Length: 823  Bit Score: 40.24  E-value: 3.68e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 297295050 384 GYTPLHLAALHGHEDaAVLLVVRLGAQVNVRDHSGRRA 421
Cdd:PLN03192 558 GRTPLHIAASKGYED-CVLVLLKHACNVHIRDANGNTA 594
flhF PRK06995
flagellar biosynthesis protein FlhF;
98-193 3.79e-03

flagellar biosynthesis protein FlhF;


Pssm-ID: 235904 [Multi-domain]  Cd Length: 484  Bit Score: 39.95  E-value: 3.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  98 AAAQPSKPTVVLPGDASAPGAPPLVPVPRQVEPPgdlGPLTETQDTPRGPASEPAQPAGERSADPPLPALELAQAPEGPS 177
Cdd:PRK06995  58 APAAAQPPPAAAPAAVSRPAAPAAEPAPWLVEHA---KRLTAQREQLVARAAAPAAPEAQAPAAPAERAAAENAARRLAR 134

                         90
                 ....*....|....*.
gi 297295050 178 ADAAPPPRASSEAASP 193
Cdd:PRK06995 135 AAAAAPRPRVPADAAA 150
Ank_3 pfam13606
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ...
 384-413 6.93e-03

Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities.


Pssm-ID: 463933 [Multi-domain]  Cd Length: 30  Bit Score: 34.16  E-value: 6.93e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 297295050  384 GYTPLHLAALHGHEDAAVLLvVRLGAQVNV 413
Cdd:pfam13606   2 GNTPLHLAARNGRLEIVKLL-LENGADINA 30
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 91-190 7.71e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 38.93  E-value: 7.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297295050  91 APFGPQGAAAQPSKPTVVLPGDASAP------GAPPLVPVPRQVEPPGDLGPLTETQDTPRGPASEPAQPAGERSADPPL 164
Cdd:PRK14951 404 AAAPAAAASAPAAPPAAAPPAPVAAPaaaapaAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAP 483

                         90       100
                 ....*....|....*....|....*.
gi 297295050 165 PALELAQAPEGPSADAAPPPRASSEA 190
Cdd:PRK14951 484 AAARLTPTEEGDVWHATVQQLAAAEA 509
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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