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Conserved domains on  [gi|109111910|ref|XP_001104510|]
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probable gluconokinase isoform X5 [Macaca mulatta]

Protein Classification

gluconokinase( domain architecture ID 10790049)

gluconokinase catalyzes the phosphoryl transfer from ATP to gluconate to form gluconate-6-phoshate

Gene Ontology:  GO:0046316|GO:0046177|GO:0005524
SCOP:  4003925

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 4-185 8.20e-86

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


:

Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 249.66  E-value: 8.20e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   4 PGALLVMGVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLDDQDRIPWLCNLHDILLRDVASGQHVVLAC 83
Cdd:COG3265    1 PMVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTDEDRAPWLEALADAIAAHLAAGEGAVLAC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  84 SALKKMYRDILTQGKDGAALkceesekeakraemqllvVHLSGSFEVISGRLLKRKGHFMPPELLQSQFETLEPPAAPEN 163
Cdd:COG3265   81 SALKRSYRDRLREGNPDVRF------------------VYLDGSRELIAERLAARKGHFMPASLLDSQFATLEPPGPDED 142

                        170       180
                 ....*....|....*....|..
gi 109111910 164 FIQISVDKNVSEIIAKIMETLK 185
Cdd:COG3265  143 AIVVDIDQPPEEIVAQILAALG 164
 
Name Accession Description Interval E-value
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 4-185 8.20e-86

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 249.66  E-value: 8.20e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   4 PGALLVMGVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLDDQDRIPWLCNLHDILLRDVASGQHVVLAC 83
Cdd:COG3265    1 PMVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTDEDRAPWLEALADAIAAHLAAGEGAVLAC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  84 SALKKMYRDILTQGKDGAALkceesekeakraemqllvVHLSGSFEVISGRLLKRKGHFMPPELLQSQFETLEPPAAPEN 163
Cdd:COG3265   81 SALKRSYRDRLREGNPDVRF------------------VYLDGSRELIAERLAARKGHFMPASLLDSQFATLEPPGPDED 142

                        170       180
                 ....*....|....*....|..
gi 109111910 164 FIQISVDKNVSEIIAKIMETLK 185
Cdd:COG3265  143 AIVVDIDQPPEEIVAQILAALG 164
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 7-169 6.65e-69

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 206.33  E-value: 6.65e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   7 LLVMGVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLDDQDRIPWLCNLHDILLRDVAS-GQHVVLACSA 85
Cdd:cd02021    2 IVVMGVSGSGKSTVGKALAERLGAPFIDGDDLHPPANIAKMAAGIPLNDEDRWPWLQALTDALLAKLASaGEGVVVACSA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  86 LKKMYRDILTQGkdgaalkceesekeakRAEMQLLVVHLSGSFEVISGRLLKRKGHFMPPELLQSQFETLEPP-AAPENF 164
Cdd:cd02021   82 LKRIYRDILRGG----------------AANPRVRFVHLDGPREVLAERLAARKGHFMPADLLDSQFETLEPPgEDEEDV 145


                 ....*
gi 109111910 165 IQISV 169
Cdd:cd02021  146 IVIDV 150
therm_gnt_kin TIGR01313
carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of ...
 7-182 1.97e-55

carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of proteins that includes thermoresistant and thermosensitve isozymes of gluconate kinase (gluconokinase) in E. coli and other related proteins; members of this family are often named by similarity to the thermostable isozyme. These proteins show homology to shikimate kinases and adenylate kinases but not to gluconate kinases from the FGGY family of carbohydrate kinases.


Pssm-ID: 273551  Cd Length: 163  Bit Score: 172.59  E-value: 1.97e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910    7 LLVMGVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLDDQDRIPWLCNLHDILLRDVASGQHVVLACSAL 86
Cdd:TIGR01313   1 FVLMGVAGSGKSTIASALAHRLGAKFIEGDDLHPAANIEKMSAGIPLNDDDRWPWLQNLNDASTAAAAKNKVGIITCSAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   87 KKMYRDILtqgkdgaalkceesekeaKRAEMQLLVVHLSGSFEVISGRLLKRKGHFMPPELLQSQFETLEPPAAPE-NFI 165
Cdd:TIGR01313  81 KRHYRDIL------------------REAEPNLHFIYLSGDKDVILERMKARKGHFMKADMLESQFAALEEPLADEtDVL 142

                         170
                  ....*....|....*..
gi 109111910  166 QISVDKNVSEIIAKIME 182
Cdd:TIGR01313 143 RVDIDQPLEGVEEDCIA 159
gntK PRK11545
gluconokinase;
10-185 1.40e-44

gluconokinase;


Pssm-ID: 236926  Cd Length: 163  Bit Score: 145.24  E-value: 1.40e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  10 MGVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLDDQDRIPWLCNLHDILLRDVASGQHVVLACSALKKM 89
Cdd:PRK11545   1 MGVSGSGKSAVASEVAHQLHAAFLDGDFLHPRRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  90 YRDILTQGKDgaalkceesekeakraemQLLVVHLSGSFEVISGRLLKRKGHFMPPELLQSQFETLEPPAAPENFIQ-IS 168
Cdd:PRK11545  81 YRDLLREGNP------------------NLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLvVD 142

                        170
                 ....*....|....*..
gi 109111910 169 VDKNVSEIIAKIMETLK 185
Cdd:PRK11545 143 IDQPLEGVVASTIEVIK 159
SKI pfam01202
Shikimate kinase;
14-185 1.81e-10

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 56.82  E-value: 1.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   14 GSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLD--DQDRIPWLcnlhdILLRDVASGQHVVLAC---SALKK 88
Cdd:pfam01202   2 GAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEgeEGFRRLES-----EVLKELLAEHGLVIATgggAVLSE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   89 MYRDILTQGKdgaalkceesekeakraemqlLVVHLSGSFEVISGRLLKRKG-----HFMPPELLQSQFETLEPP----A 159
Cdd:pfam01202  77 ENRDLLKERG---------------------IVIYLDAPLEVLLERLKRDKTrpllqNKDPEEELLELLFEERDPlyeeA 135

                         170       180
                  ....*....|....*....|....*.
gi 109111910  160 ApeNFIQISVDKNVSEIIAKIMETLK 185
Cdd:pfam01202 136 A--DIVIDTDESSPEEVATEILEALE 159
 
Name Accession Description Interval E-value
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 4-185 8.20e-86

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 249.66  E-value: 8.20e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   4 PGALLVMGVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLDDQDRIPWLCNLHDILLRDVASGQHVVLAC 83
Cdd:COG3265    1 PMVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTDEDRAPWLEALADAIAAHLAAGEGAVLAC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  84 SALKKMYRDILTQGKDGAALkceesekeakraemqllvVHLSGSFEVISGRLLKRKGHFMPPELLQSQFETLEPPAAPEN 163
Cdd:COG3265   81 SALKRSYRDRLREGNPDVRF------------------VYLDGSRELIAERLAARKGHFMPASLLDSQFATLEPPGPDED 142

                        170       180
                 ....*....|....*....|..
gi 109111910 164 FIQISVDKNVSEIIAKIMETLK 185
Cdd:COG3265  143 AIVVDIDQPPEEIVAQILAALG 164
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 7-169 6.65e-69

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 206.33  E-value: 6.65e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   7 LLVMGVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLDDQDRIPWLCNLHDILLRDVAS-GQHVVLACSA 85
Cdd:cd02021    2 IVVMGVSGSGKSTVGKALAERLGAPFIDGDDLHPPANIAKMAAGIPLNDEDRWPWLQALTDALLAKLASaGEGVVVACSA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  86 LKKMYRDILTQGkdgaalkceesekeakRAEMQLLVVHLSGSFEVISGRLLKRKGHFMPPELLQSQFETLEPP-AAPENF 164
Cdd:cd02021   82 LKRIYRDILRGG----------------AANPRVRFVHLDGPREVLAERLAARKGHFMPADLLDSQFETLEPPgEDEEDV 145


                 ....*
gi 109111910 165 IQISV 169
Cdd:cd02021  146 IVIDV 150
therm_gnt_kin TIGR01313
carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of ...
 7-182 1.97e-55

carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of proteins that includes thermoresistant and thermosensitve isozymes of gluconate kinase (gluconokinase) in E. coli and other related proteins; members of this family are often named by similarity to the thermostable isozyme. These proteins show homology to shikimate kinases and adenylate kinases but not to gluconate kinases from the FGGY family of carbohydrate kinases.


Pssm-ID: 273551  Cd Length: 163  Bit Score: 172.59  E-value: 1.97e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910    7 LLVMGVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLDDQDRIPWLCNLHDILLRDVASGQHVVLACSAL 86
Cdd:TIGR01313   1 FVLMGVAGSGKSTIASALAHRLGAKFIEGDDLHPAANIEKMSAGIPLNDDDRWPWLQNLNDASTAAAAKNKVGIITCSAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   87 KKMYRDILtqgkdgaalkceesekeaKRAEMQLLVVHLSGSFEVISGRLLKRKGHFMPPELLQSQFETLEPPAAPE-NFI 165
Cdd:TIGR01313  81 KRHYRDIL------------------REAEPNLHFIYLSGDKDVILERMKARKGHFMKADMLESQFAALEEPLADEtDVL 142

                         170
                  ....*....|....*..
gi 109111910  166 QISVDKNVSEIIAKIME 182
Cdd:TIGR01313 143 RVDIDQPLEGVEEDCIA 159
gntK PRK11545
gluconokinase;
10-185 1.40e-44

gluconokinase;


Pssm-ID: 236926  Cd Length: 163  Bit Score: 145.24  E-value: 1.40e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  10 MGVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLDDQDRIPWLCNLHDILLRDVASGQHVVLACSALKKM 89
Cdd:PRK11545   1 MGVSGSGKSAVASEVAHQLHAAFLDGDFLHPRRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  90 YRDILTQGKDgaalkceesekeakraemQLLVVHLSGSFEVISGRLLKRKGHFMPPELLQSQFETLEPPAAPENFIQ-IS 168
Cdd:PRK11545  81 YRDLLREGNP------------------NLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLvVD 142

                        170
                 ....*....|....*..
gi 109111910 169 VDKNVSEIIAKIMETLK 185
Cdd:PRK11545 143 IDQPLEGVVASTIEVIK 159
idnK PRK09825
gluconokinase;
3-176 3.32e-43

gluconokinase;


Pssm-ID: 182097  Cd Length: 176  Bit Score: 142.09  E-value: 3.32e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   3 APGALLVMGVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLDDQDRIPWLCNLHDILLRDVASGQHVVLA 82
Cdd:PRK09825   2 AGESYILMGVSGSGKSLIGSKIAALFSAKFIDGDDLHPAKNIDKMSQGIPLTDEDRLPWLERLNDASYSLYKKNETGFIV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  83 CSALKKMYRDILTQGKDGaalkceesekeakraemqllvVH---LSGSFEVISGRLLKRKGHFMPPELLQSQFETLEPPA 159
Cdd:PRK09825  82 CSSLKKQYRDILRKSSPN---------------------VHflwLDGDYETILARMQRRAGHFMPPDLLQSQFDALERPC 140

                        170
                 ....*....|....*...
gi 109111910 160 APE-NFIQISVDKNVSEI 176
Cdd:PRK09825 141 ADEhDIARIDVNHDIENV 158
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
7-176 3.90e-12

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 61.08  E-value: 3.90e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   7 LLVMGVSGSGKSTVGALLASELGWKFYDADdyhpEEnRKKM-GKGIPL--DDQDRIPWLCN-LHDILLRDVASGQHVVLA 82
Cdd:COG0645    2 ILVCGLPGSGKSTLARALAERLGAVRLRSD----VV-RKRLfGAGLAPleRSPEATARTYArLLALARELLAAGRSVILD 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  83 CSALKKMYRDiltqgkDGAALkceesekeAKRAEMQLLVVHLSGSFEVISGRLLKRKGHFMPP----ELLQSQFETLEPP 158
Cdd:COG0645   77 ATFLRRAQRE------AFRAL--------AEEAGAPFVLIWLDAPEEVLRERLEARNAEGGDSdatwEVLERQLAFEEPL 142

                        170       180
                 ....*....|....*....|..
gi 109111910 159 AAPENFIQI----SVDKNVSEI 176
Cdd:COG0645  143 TEDEGFLLVvdtsGLEEALAAL 164
SKI pfam01202
Shikimate kinase;
14-185 1.81e-10

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 56.82  E-value: 1.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   14 GSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLD--DQDRIPWLcnlhdILLRDVASGQHVVLAC---SALKK 88
Cdd:pfam01202   2 GAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEgeEGFRRLES-----EVLKELLAEHGLVIATgggAVLSE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   89 MYRDILTQGKdgaalkceesekeakraemqlLVVHLSGSFEVISGRLLKRKG-----HFMPPELLQSQFETLEPP----A 159
Cdd:pfam01202  77 ENRDLLKERG---------------------IVIYLDAPLEVLLERLKRDKTrpllqNKDPEEELLELLFEERDPlyeeA 135

                         170       180
                  ....*....|....*....|....*.
gi 109111910  160 ApeNFIQISVDKNVSEIIAKIMETLK 185
Cdd:pfam01202 136 A--DIVIDTDESSPEEVATEILEALE 159
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 11-185 2.16e-09

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 53.98  E-value: 2.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  11 GVSGSGKSTVGALLASELGWKFYDADDyhpeENRKKMGKGIPlddqdripwlcnlhDI---------------LLRDVAS 75
Cdd:COG0703    5 GMMGAGKSTVGRLLAKRLGLPFVDTDA----EIEERAGMSIP--------------EIfaeegeagfrelereVLAELLE 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  76 GQHVVLACSAlkkmyrdiltqgkdGAALkceeseKEAKRAEMQL--LVVHLSGSFEVISGRLLKRKG-----HFMPPELL 148
Cdd:COG0703   67 EENAVIATGG--------------GAVL------SPENRELLKEhgTVVYLDASPETLLERLRRDDNrpllqGEDPRERL 126

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 109111910 149 QSQFETLEP----PAApenfIQISVD-KNVSEIIAKIMETLK 185
Cdd:COG0703  127 EELLAEREPlyreVAD----ITVDTDgRSPEEVVDEILEALE 164
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 11-38 8.56e-08

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 49.09  E-value: 8.56e-08
                         10        20
                 ....*....|....*....|....*...
gi 109111910  11 GVSGSGKSTVGALLASELGWKFYDADDY 38
Cdd:cd00464    6 GMMGAGKTTVGRLLAKALGLPFVDLDEL 33
aroK PRK00131
shikimate kinase; Reviewed
 11-52 8.01e-07

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 47.11  E-value: 8.01e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 109111910  11 GVSGSGKSTVGALLASELGWKFYDADDyhpeENRKKMGKGIP 52
Cdd:PRK00131  11 GFMGAGKSTIGRLLAKRLGYDFIDTDH----LIEARAGKSIP 48
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 7-158 1.05e-06

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 46.15  E-value: 1.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910    7 LLVM-GVSGSGKSTVGALLASELGWKFYDADDYhpeenRKKM---GKGIPLDDQDRIPWLCN-LHDILLRDVASGQHVVL 81
Cdd:pfam13671   1 LILLvGLPGSGKSTLARRLLEELGAVRLSSDDE-----RKRLfgeGRPSISYYTDATDRTYErLHELARIALRAGRPVIL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910   82 ACSALKKMYRDILTQGkdgaalkceesekeAKRAEMQLLVVHLSGSFEVISGRLLKRKGH-----FMPPELLQSQFETLE 156
Cdd:pfam13671  76 DATNLRRDERARLLAL--------------AREYGVPVRIVVFEAPEEVLRERLAARARAggdpsDVPEEVLDRQKARFE 141


                  ..
gi 109111910  157 PP 158
Cdd:pfam13671 142 PP 143
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 11-42 9.39e-06

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 43.63  E-value: 9.39e-06
                         10        20        30
                 ....*....|....*....|....*....|..
gi 109111910  11 GVSGSGKSTVGALLASELGWKFYDADDYHPEE 42
Cdd:cd02020    6 GPAGSGKSTVAKLLAKKLGLPYLDTGGIRTEE 37
PRK06217 PRK06217
hypothetical protein; Validated
 7-49 3.71e-05

hypothetical protein; Validated


Pssm-ID: 168472  Cd Length: 183  Bit Score: 42.34  E-value: 3.71e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 109111910   7 LLVMGVSGSGKSTVGALLASELGWKFYDADDYH-------------PEENRKKMGK 49
Cdd:PRK06217   4 IHITGASGSGTTTLGAALAERLDIPHLDTDDYFwlptdppfttkrpPEERLRLLLE 59
aroL PRK03731
shikimate kinase AroL;
7-38 4.22e-05

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 41.85  E-value: 4.22e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 109111910   7 LLVMGVSGSGKSTVGALLASELGWKFYDADDY 38
Cdd:PRK03731   5 LFLVGARGCGKTTVGMALAQALGYRFVDTDQW 36
Pgk2 COG2074
2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and ...
 1-31 1.88e-04

2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 441677  Cd Length: 207  Bit Score: 40.70  E-value: 1.88e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 109111910   1 MAAPGALLVMGVSGSGKSTVGALLASELGWK 31
Cdd:COG2074    3 MKRPRIILIGGASGVGKSTIAAELARRLGIP 33
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
13-34 1.89e-04

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 40.19  E-value: 1.89e-04
                         10        20
                 ....*....|....*....|..
gi 109111910  13 SGSGKSTVGALLASELGWKFYD 34
Cdd:COG1102    9 PGSGGTTIAKRLAEKLGLPLYD 30
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
11-81 1.90e-04

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 40.39  E-value: 1.90e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109111910  11 GVSGSGKSTVGALLASELGWKFYD-----------ADDyhpeenrkkmgKGIPLDDQDRIPWLCNLHDILLRDVASGQHV 79
Cdd:COG0283    7 GPAGSGKSTVAKALAKRLGYHYLDtgamyravalaALR-----------NGIDLDDEEALAALARNLDIEFETDPGGQRV 75


                 ..
gi 109111910  80 VL 81
Cdd:COG0283   76 FL 77
PRK13949 PRK13949
shikimate kinase; Provisional
 7-48 3.21e-04

shikimate kinase; Provisional


Pssm-ID: 140006 [Multi-domain]  Cd Length: 169  Bit Score: 39.71  E-value: 3.21e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 109111910   7 LLVMGVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMG 48
Cdd:PRK13949   4 IFLVGYMGAGKTTLGKALARELGLSFIDLDFFIENRFHKTVG 45
PRK13946 PRK13946
shikimate kinase; Provisional
 6-37 5.68e-04

shikimate kinase; Provisional


Pssm-ID: 184411 [Multi-domain]  Cd Length: 184  Bit Score: 38.75  E-value: 5.68e-04
                         10        20        30
                 ....*....|....*....|....*....|..
gi 109111910   6 ALLVMGVSGSGKSTVGALLASELGWKFYDADD 37
Cdd:PRK13946  12 TVVLVGLMGAGKSTVGRRLATMLGLPFLDADT 43
PLN02199 PLN02199
shikimate kinase
 6-36 5.86e-04

shikimate kinase


Pssm-ID: 177850 [Multi-domain]  Cd Length: 303  Bit Score: 39.68  E-value: 5.86e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 109111910   6 ALLVMGVSGSGKSTVGALLASELGWKFYDAD 36
Cdd:PLN02199 104 SMYLVGMMGSGKTTVGKLMSKVLGYTFFDCD 134
PRK06547 PRK06547
hypothetical protein; Provisional
 8-40 1.21e-03

hypothetical protein; Provisional


Pssm-ID: 235825  Cd Length: 172  Bit Score: 37.80  E-value: 1.21e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 109111910   8 LVMGVSGSGKSTVGALLASELGWKFYDADDYHP 40
Cdd:PRK06547  19 LIDGRSGSGKTTLAGALAARTGFQLVHLDDLYP 51
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 11-34 2.03e-03

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 37.67  E-value: 2.03e-03
                          10        20
                  ....*....|....*....|....
gi 109111910   11 GVSGSGKSTVGALLASELGWKFYD 34
Cdd:pfam02224   5 GPSGSGKSTVARILARKLGYKYLD 28
aroK PRK05057
shikimate kinase AroK;
1-37 2.26e-03

shikimate kinase AroK;


Pssm-ID: 235335 [Multi-domain]  Cd Length: 172  Bit Score: 37.00  E-value: 2.26e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 109111910   1 MAAPGALLVMGVSGSGKSTVGALLASELGWKFYDADD 37
Cdd:PRK05057   1 MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQ 37
CoaE COG0237
Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the ...
 14-36 3.09e-03

Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 440007  Cd Length: 193  Bit Score: 36.97  E-value: 3.09e-03
                         10        20
                 ....*....|....*....|...
gi 109111910  14 GSGKSTVGALLAsELGWKFYDAD 36
Cdd:COG0237   11 GSGKSTVARMFA-ELGAPVIDAD 32
PRK04182 PRK04182
cytidylate kinase; Provisional
 9-37 4.50e-03

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 36.32  E-value: 4.50e-03
                         10        20
                 ....*....|....*....|....*....
gi 109111910   9 VMGVSGSGKSTVGALLASELGWKFYDADD 37
Cdd:PRK04182   5 ISGPPGSGKTTVARLLAEKLGLKHVSAGE 33
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 4-33 4.90e-03

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 36.81  E-value: 4.90e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 109111910   4 PGALLVMGVSGSGKSTVGALLASELGWKFY 33
Cdd:COG0464  191 PRGLLLYGPPGTGKTLLARALAGELGLPLI 220
PRK11860 PRK11860
bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;
11-59 6.98e-03

bifunctional 3-phosphoshikimate 1-carboxyvinyltransferase/cytidylate kinase;


Pssm-ID: 237003 [Multi-domain]  Cd Length: 661  Bit Score: 36.56  E-value: 6.98e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 109111910  11 GVSGSGKSTVGALLASELGWKFYDADDYHPEENRKKMGKGIPLDDQDRI 59
Cdd:PRK11860 449 GPTASGKGTVAARVAEALGYHYLDSGALYRLTALAALRAGVALDDEAAI 497
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 6-32 9.35e-03

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 35.70  E-value: 9.35e-03
                         10        20
                 ....*....|....*....|....*..
gi 109111910   6 ALLvmGVSGSGKSTVGALLASELGWKF 32
Cdd:PRK08154 137 ALI--GLRGAGKSTLGRMLAARLGVPF 161
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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