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Conserved domains on  [gi|1622839134|ref|XP_001102577|]
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transmembrane protein 121B [Macaca mulatta]

Protein Classification

transmembrane protein 121 domain-containing protein( domain architecture ID 10633201)

transmembrane protein 121 domain-containing protein such as transmembrane protein 121B that is expressed in a variety of tissues, including the eye and the brain, and is involved in the development of the eye and the brain

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CECR6_TMEM121 pfam14997
CECR6/TMEM121 family; This family includes Cat eye syndrome critical region protein 6, a ...
312-518 7.22e-58

CECR6/TMEM121 family; This family includes Cat eye syndrome critical region protein 6, a protein which has been identified in a screen for candidate genes for the developmental disorder Cat Eye Syndrome (CES). It also includes the TMEM121 transmembrane proteins. The function of this family is unknown.


:

Pssm-ID: 464432  Cd Length: 194  Bit Score: 192.11  E-value: 7.22e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839134 312 AFAYLAWLIYSIAFTPKVVLILGTSILD-LIELRApFGTTGFRLTMALSVPLLYSLVRAISEAGAPPGsagplllqPQRH 390
Cdd:pfam14997   1 PYAYIAWFLYVIVLVPKVAFIFQNEIADeLIRLDV-FGPKALKVLLSLSVPLLFLLLVAIHHMEYPRS--------PRKL 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839134 391 RAAGCFLGTCLDLLDSFTLVELMLEG-RVPLPAHLRYLLIAVYFLTLASPVLWLYELNAAAAaaaaswGQASGPGSCSRL 469
Cdd:pfam14997  72 YLRSLCLWVCLDLLDSFDLLEILLEPeHTGLPLWLEGLILVVACINLFLPTVALYELSVSKF------GGLVLIVPCKML 145
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1622839134 470 LRLLGGCLVDVPLLALRCLLVVSYQQPLSIFMLKNLFFLGCRGLEALEG 518
Cdd:pfam14997 146 YPLLSLLLVNVPFLVIRGLLWFRYNRDVSIFLGKNVFFIGIKLCEIVEY 194
 
Name Accession Description Interval E-value
CECR6_TMEM121 pfam14997
CECR6/TMEM121 family; This family includes Cat eye syndrome critical region protein 6, a ...
312-518 7.22e-58

CECR6/TMEM121 family; This family includes Cat eye syndrome critical region protein 6, a protein which has been identified in a screen for candidate genes for the developmental disorder Cat Eye Syndrome (CES). It also includes the TMEM121 transmembrane proteins. The function of this family is unknown.


Pssm-ID: 464432  Cd Length: 194  Bit Score: 192.11  E-value: 7.22e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839134 312 AFAYLAWLIYSIAFTPKVVLILGTSILD-LIELRApFGTTGFRLTMALSVPLLYSLVRAISEAGAPPGsagplllqPQRH 390
Cdd:pfam14997   1 PYAYIAWFLYVIVLVPKVAFIFQNEIADeLIRLDV-FGPKALKVLLSLSVPLLFLLLVAIHHMEYPRS--------PRKL 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839134 391 RAAGCFLGTCLDLLDSFTLVELMLEG-RVPLPAHLRYLLIAVYFLTLASPVLWLYELNAAAAaaaaswGQASGPGSCSRL 469
Cdd:pfam14997  72 YLRSLCLWVCLDLLDSFDLLEILLEPeHTGLPLWLEGLILVVACINLFLPTVALYELSVSKF------GGLVLIVPCKML 145
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1622839134 470 LRLLGGCLVDVPLLALRCLLVVSYQQPLSIFMLKNLFFLGCRGLEALEG 518
Cdd:pfam14997 146 YPLLSLLLVNVPFLVIRGLLWFRYNRDVSIFLGKNVFFIGIKLCEIVEY 194
 
Name Accession Description Interval E-value
CECR6_TMEM121 pfam14997
CECR6/TMEM121 family; This family includes Cat eye syndrome critical region protein 6, a ...
312-518 7.22e-58

CECR6/TMEM121 family; This family includes Cat eye syndrome critical region protein 6, a protein which has been identified in a screen for candidate genes for the developmental disorder Cat Eye Syndrome (CES). It also includes the TMEM121 transmembrane proteins. The function of this family is unknown.


Pssm-ID: 464432  Cd Length: 194  Bit Score: 192.11  E-value: 7.22e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839134 312 AFAYLAWLIYSIAFTPKVVLILGTSILD-LIELRApFGTTGFRLTMALSVPLLYSLVRAISEAGAPPGsagplllqPQRH 390
Cdd:pfam14997   1 PYAYIAWFLYVIVLVPKVAFIFQNEIADeLIRLDV-FGPKALKVLLSLSVPLLFLLLVAIHHMEYPRS--------PRKL 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622839134 391 RAAGCFLGTCLDLLDSFTLVELMLEG-RVPLPAHLRYLLIAVYFLTLASPVLWLYELNAAAAaaaaswGQASGPGSCSRL 469
Cdd:pfam14997  72 YLRSLCLWVCLDLLDSFDLLEILLEPeHTGLPLWLEGLILVVACINLFLPTVALYELSVSKF------GGLVLIVPCKML 145
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1622839134 470 LRLLGGCLVDVPLLALRCLLVVSYQQPLSIFMLKNLFFLGCRGLEALEG 518
Cdd:pfam14997 146 YPLLSLLLVNVPFLVIRGLLWFRYNRDVSIFLGKNVFFIGIKLCEIVEY 194
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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