NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|109018155|ref|XP_001099084|]
View 

sushi domain-containing protein 4 isoform X1 [Macaca mulatta]

Protein Classification

beta-2-glycoprotein 1( domain architecture ID 13269567)

beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PHA02639 super family cl31493
EEV host range protein; Provisional
 31-239 1.95e-13

EEV host range protein; Provisional


The actual alignment was detected with superfamily member PHA02639:

Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 70.85  E-value: 1.95e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155  31 LAVILWFQLALCFgpaqlTGGFDDLQaCADPGVPENGFRTPSGGVFFEGSVTRFHCQDGFKLKGATKRLCMKYFNGTLgW 110
Cdd:PHA02639   1 MKIILYLFIGVCY-----VHGVKSIY-CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 111 ipSDKS-ICVQEECR-IPQIEDAEIHNK--TYRYGEKLIITCHEGFKIRYPDLYNMFSLCRDDGTWN-NLPVCQ--GCLR 183
Cdd:PHA02639  74 --SNKApFCMLKECNdPPSIINGKIYNKreMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRF 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 109018155 184 PlASTNGYVNISEFQISFPVGTVISYRCFPGFKLDGSAYLECLHNLIWSSSPPRCL 239
Cdd:PHA02639 152 P-ALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 246-300 3.65e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


:

Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 3.65e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 109018155   246 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 300
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
 
Name Accession Description Interval E-value
PHA02639 PHA02639
EEV host range protein; Provisional
 31-239 1.95e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 70.85  E-value: 1.95e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155  31 LAVILWFQLALCFgpaqlTGGFDDLQaCADPGVPENGFRTPSGGVFFEGSVTRFHCQDGFKLKGATKRLCMKYFNGTLgW 110
Cdd:PHA02639   1 MKIILYLFIGVCY-----VHGVKSIY-CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 111 ipSDKS-ICVQEECR-IPQIEDAEIHNK--TYRYGEKLIITCHEGFKIRYPDLYNMFSLCRDDGTWN-NLPVCQ--GCLR 183
Cdd:PHA02639  74 --SNKApFCMLKECNdPPSIINGKIYNKreMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRF 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 109018155 184 PlASTNGYVNISEFQISFPVGTVISYRCFPGFKLDGSAYLECLHNLIWSSSPPRCL 239
Cdd:PHA02639 152 P-ALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 181-238 5.72e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 57.86  E-value: 5.72e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 109018155 181 CLRPLASTNGYVNISefQISFPVGTVISYRCFPGFKLDGSAYLECLHNLIWSSSPPRC 238
Cdd:cd00033    1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 181-238 2.82e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.61  E-value: 2.82e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 109018155   181 CLRPLASTNGYVNISEFqiSFPVGTVISYRCFPGFKLDGSAYLECLHNLIWSSSPPRC 238
Cdd:smart00032   1 CPPPPDIENGTVTSSSG--TYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 246-300 3.65e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 3.65e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 109018155   246 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 300
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 246-297 8.00e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.00  E-value: 8.00e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 109018155 246 CPLPPMVSHGDFVCHPrpcERYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEW 297
Cdd:cd00033    1 CPPPPVPENGTVTGSK---GSYSYGSTVTYSCNEGYTLVGS-STITCTeNGGW 49
Sushi pfam00084
Sushi repeat (SCR repeat);
200-238 1.47e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 1.47e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 109018155  200 SFPVGTVISYRCFPGFKLDGSAYLECLHNLIWSSSPPRC 238
Cdd:pfam00084  18 EYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
246-297 6.67e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.26  E-value: 6.67e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 109018155  246 CPLPPMVSHGDFVChprPCERYNHGTVVEFYCDPGYSLTSDYKyITCQ-YGEW 297
Cdd:pfam00084   1 CPPPPDIPNGKVSA---TKNEYNYGASVSYECDPGYRLVGSPT-ITCQeDGTW 49
 
Name Accession Description Interval E-value
PHA02639 PHA02639
EEV host range protein; Provisional
 31-239 1.95e-13

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 70.85  E-value: 1.95e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155  31 LAVILWFQLALCFgpaqlTGGFDDLQaCADPGVPENGFRTPSGGVFFEGSVTRFHCQDGFKLKGATKRLCMKYFNGTLgW 110
Cdd:PHA02639   1 MKIILYLFIGVCY-----VHGVKSIY-CDKPDDISNGFITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAI-W 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 111 ipSDKS-ICVQEECR-IPQIEDAEIHNK--TYRYGEKLIITCHEGFKIRYPDLYNMFSLCRDDGTWN-NLPVCQ--GCLR 183
Cdd:PHA02639  74 --SNKApFCMLKECNdPPSIINGKIYNKreMYKVGDEIYYVCNEHKGVQYSLVGNEKITCIQDKSWKpDPPICKmiNCRF 151

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 109018155 184 PlASTNGYVNISEFQISFPVGTVISYRCFPGFKLDGSAYLECLHNLIWSSSPPRCL 239
Cdd:PHA02639 152 P-ALQNGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 58-239 2.05e-13

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 70.45  E-value: 2.05e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155  58 CADPGVPENGfRTPSGGVFFEGSVTrFHCQDGFKLKGATKRLCMKYFNGTLGWIPsDKSICVQEECRIPQIEDAEIHN-- 135
Cdd:PHA02927  86 CPSPRDIDNG-QLDIGGVDFGSSIT-YSCNSGYQLIGESKSYCELGSTGSMVWNP-EAPICESVKCQSPPSISNGRHNgy 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 136 -KTYRYGEKLIITCHEGFKIrypdLYNMFSLCrDDGTWNNLPVCQ--GCLRPlASTNGYVNiSEFQISFPVGTVISYRCF 212
Cdd:PHA02927 163 eDFYTDGSVVTYSCNSGYSL----IGNSGVLC-SGGEWSDPPTCQivKCPHP-TISNGYLS-SGFKRSYSYNDNVDFKCK 235

                        170       180
                 ....*....|....*....|....*..
gi 109018155 213 PGFKLDGSAYLECLHNLIWSSSPPRCL 239
Cdd:PHA02927 236 YGYKLSGSSSSTCSPGNTWQPELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 181-238 5.72e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 57.86  E-value: 5.72e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 109018155 181 CLRPLASTNGYVNISefQISFPVGTVISYRCFPGFKLDGSAYLECLHNLIWSSSPPRC 238
Cdd:cd00033    1 CPPPPVPENGTVTGS--KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 181-238 2.82e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.61  E-value: 2.82e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 109018155   181 CLRPLASTNGYVNISEFqiSFPVGTVISYRCFPGFKLDGSAYLECLHNLIWSSSPPRC 238
Cdd:smart00032   1 CPPPPDIENGTVTSSSG--TYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 135-297 3.28e-10

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 60.82  E-value: 3.28e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 135 NKTYRYGEKLIITCHEGFkiRYPDLYNMFSLCRDDG-TWNNLPVCQGCLRPLASTNGYVNISEFQIsfpvGTVISYRCFP 213
Cdd:PHA02927  41 NANYNIGDTIEYLCLPGY--RKQKMGPIYAKCTGTGwTLFNQCIKRRCPSPRDIDNGQLDIGGVDF----GSSITYSCNS 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 214 GFKLDGSAYLEC----LHNLIWSSSPPRClalEAQVCPLPPMVSHGDfvcHPRPCERYNHGTVVEFYCDPGYSLTSDYKy 289
Cdd:PHA02927 115 GYQLIGESKSYCelgsTGSMVWNPEAPIC---ESVKCQSPPSISNGR---HNGYEDFYTDGSVVTYSCNSGYSLIGNSG- 187


                 ....*...
gi 109018155 290 ITCQYGEW 297
Cdd:PHA02927 188 VLCSGGEW 195
PHA02817 PHA02817
EEV Host range protein; Provisional
 116-238 1.42e-08

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 55.33  E-value: 1.42e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 116 SICVQEECRIP-QIEDAEIHNK--TYRYGEKLIITCHEGFK-IRYPDLYNMFSLCRDDGTWN-NLPVCQ--GCLRPlAST 188
Cdd:PHA02817  17 SLCDLNKCCYPpSIKNGYIYNKktEYNIGSNVTFFCGNNTRgVRYTLVGEKNIICEKDGKWNkEFPVCKiiRCRFP-ALQ 95

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 109018155 189 NGYVNISEFQISFPVGTVISYRCFPGFKLDGSAYLECLHNLIWSSSPPRC 238
Cdd:PHA02817  96 NGFVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 246-300 3.65e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 49.83  E-value: 3.65e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 109018155   246 CPLPPMVSHGDFVCHPRPcerYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEWFPS 300
Cdd:smart00032   1 CPPPPDIENGTVTSSSGT---YSYGDTVTYSCDPGYTLIGS-STITCLeNGTWSPP 52
PHA02831 PHA02831
EEV host range protein; Provisional
 105-239 6.36e-08

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 53.84  E-value: 6.36e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 105 NGTlgWipSDKSICV-QEECRIP-QIEDAEIHNKT--YRYGEKLIITCHEGFKIRYPDLYNMFSLCRDdGTW-NNLPVCQ 179
Cdd:PHA02831  63 NGS--W--STKNMCIgKRNCKDPvTILNGYIKNKKdqYSFGDSVTYACKVNKLEKYSIVGNETVKCIN-KQWvPKYPVCK 137

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 109018155 180 --GCLRPlASTNGYVNIseFQISFPVGTVISYRCFPGFKLDGSAYLECLHNLIWSSSPPRCL 239
Cdd:PHA02831 138 liRCKYP-ALQNGFLNV--FEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCV 196
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 246-297 8.00e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 49.00  E-value: 8.00e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 109018155 246 CPLPPMVSHGDFVCHPrpcERYNHGTVVEFYCDPGYSLTSDyKYITCQ-YGEW 297
Cdd:cd00033    1 CPPPPVPENGTVTGSK---GSYSYGSTVTYSCNEGYTLVGS-STITCTeNGGW 49
Sushi pfam00084
Sushi repeat (SCR repeat);
200-238 1.47e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 1.47e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 109018155  200 SFPVGTVISYRCFPGFKLDGSAYLECLHNLIWSSSPPRC 238
Cdd:pfam00084  18 EYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 58-101 7.26e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 46.30  E-value: 7.26e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 109018155  58 CADPGVPENGFRTPSGGVFFEGSVTRFHCQDGFKLKGATKRLCM 101
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCT 44
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 55-299 1.62e-06

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 49.65  E-value: 1.62e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155  55 LQACADPGVP-----ENGFRTPSGGVFFEGSVTRFHCQDGFKLK--GATKRLCmkyfNGTlGWIPSDKsiCVQEECRIPQ 127
Cdd:PHA02927  18 LSCCTIPSRPinmkfKNSVETDANANYNIGDTIEYLCLPGYRKQkmGPIYAKC----TGT-GWTLFNQ--CIKRRCPSPR 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 128 -IEDAEIHNKTYRYGEKLIITCHEGFKI-----RYPDLYNMFSLcrddgTWN-NLPVCQG--CLRPLASTNGYVNisEFQ 198
Cdd:PHA02927  91 dIDNGQLDIGGVDFGSSITYSCNSGYQLigeskSYCELGSTGSM-----VWNpEAPICESvkCQSPPSISNGRHN--GYE 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 199 ISFPVGTVISYRCFPGFKLDGSAYLECLHNLiWSSsPPRCLALEaqvCPlPPMVSHGDFVCHPRpcERYNHGTVVEFYCD 278
Cdd:PHA02927 164 DFYTDGSVVTYSCNSGYSLIGNSGVLCSGGE-WSD-PPTCQIVK---CP-HPTISNGYLSSGFK--RSYSYNDNVDFKCK 235

                        250       260
                 ....*....|....*....|..
gi 109018155 279 PGYSLTSDYKYiTCQYGE-WFP 299
Cdd:PHA02927 236 YGYKLSGSSSS-TCSPGNtWQP 256
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 58-101 2.33e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 44.82  E-value: 2.33e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 109018155    58 CADPGVPENGFRTPSGGVFFEGSVTRFHCQDGFKLKGATKRLCM 101
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYGDTVTYSCDPGYTLIGSSTITCL 44
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 93-248 2.59e-06

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 49.31  E-value: 2.59e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155  93 KGATKRLCMKYFNGTLGWipSDKSICVQEECRIPQIEDAEIH--NKTYRYGEKLIITCHEGFKIrypdLYNMFSLCRDDg 170
Cdd:PHA02954 102 KDETKYFRCEEKNGNTSW--NDTVTCPNAECQPLQLEHGSCQpvKEKYSFGEHITINCDVGYEV----IGASYISCTAN- 174

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 109018155 171 TWNNLPVCQGCLRPLASTNGYVNISEFQIsfpvGTVISYRCFPGFKLDGSAYLECLHNLiWSSSPPRCLALEAQVCPL 248
Cdd:PHA02954 175 SWNVIPSCQQKCDIPSLSNGLISGSTFSI----GGVIHLSCKSGFTLTGSPSSTCIDGK-WNPVLPICVRSNEEFDPV 247
Sushi pfam00084
Sushi repeat (SCR repeat);
246-297 6.67e-06

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 43.26  E-value: 6.67e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 109018155  246 CPLPPMVSHGDFVChprPCERYNHGTVVEFYCDPGYSLTSDYKyITCQ-YGEW 297
Cdd:pfam00084   1 CPPPPDIPNGKVSA---TKNEYNYGASVSYECDPGYRLVGSPT-ITCQeDGTW 49
PHA02831 PHA02831
EEV host range protein; Provisional
 135-307 1.04e-05

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 47.29  E-value: 1.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 135 NKTYRYGEKLIITCHEGFKirypdlyNMFSLCrDDGTWNNLPVCQG---CLRPLASTNGYVNISEFQISFpvGTVISYRC 211
Cdd:PHA02831  37 NKVYEENENLEYKCNNNFD-------KVFVTC-NNGSWSTKNMCIGkrnCKDPVTILNGYIKNKKDQYSF--GDSVTYAC 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 212 ----FPGFKLDGSAYLECLhNLIWSSSPPRCLALEAQVcplpPMVSHGDFVCHPRpceRYNHGTVVEFYCDPGY----SL 283
Cdd:PHA02831 107 kvnkLEKYSIVGNETVKCI-NKQWVPKYPVCKLIRCKY----PALQNGFLNVFEK---KFYYGDIVNFKCKKGFillgSS 178

                        170       180
                 ....*....|....*....|....*
gi 109018155 284 TSdykyiTCQYGE-WFPSYQvYCIK 307
Cdd:PHA02831 179 VS-----TCDINSiWYPGIP-KCVK 197
PHA02639 PHA02639
EEV host range protein; Provisional
 181-299 2.77e-05

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 45.81  E-value: 2.77e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155 181 CLRPLASTNGYvnISEFQISFPVGTVISYRCFPGFKLDGSAYLECL---HNLIWSSSPPRCLALEaqvCPLPPMVSHGDf 257
Cdd:PHA02639  22 CDKPDDISNGF--ITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIkdkNNAIWSNKAPFCMLKE---CNDPPSIINGK- 95

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 109018155 258 VCHPRpcERYNHGTVVEFYCDP----GYSLTSDYKYITCQYGEWFP 299
Cdd:PHA02639  96 IYNKR--EMYKVGDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKP 139
Sushi pfam00084
Sushi repeat (SCR repeat);
58-100 4.26e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 38.25  E-value: 4.26e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 109018155   58 CADPGVPENGFRTPSGGVFFEGSVTRFHCQDGFKLKGATKRLC 100
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITC 43
Sushi pfam00084
Sushi repeat (SCR repeat);
123-178 1.27e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 37.09  E-value: 1.27e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 109018155  123 CRIPQ-IEDAEIH--NKTYRYGEKLIITCHEGFKIRYPDLYnmfsLCRDDGTWNNL-PVC 178
Cdd:pfam00084   1 CPPPPdIPNGKVSatKNEYNYGASVSYECDPGYRLVGSPTI----TCQEDGTWSPPfPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 126-178 3.80e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 35.58  E-value: 3.80e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 109018155   126 PQIEDAEI--HNKTYRYGEKLIITCHEGFKIRYPDlynmFSLCRDDGTWNN-LPVC 178
Cdd:smart00032   5 PDIENGTVtsSSGTYSYGDTVTYSCDPGYTLIGSS----TITCLENGTWSPpPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 126-179 9.23e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 34.75  E-value: 9.23e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 109018155 126 PQIEDAEI--HNKTYRYGEKLIITCHEGFKIRYPDlynmFSLCRDDGTWNN-LPVCQ 179
Cdd:cd00033    5 PVPENGTVtgSKGSYSYGSTVTYSCNEGYTLVGSS----TITCTENGGWSPpPPTCE 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH