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Conserved domains on  [gi|1752263663|ref|WP_150390319|]
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TonB-dependent receptor [Aeromonas veronii]

Protein Classification

TonB-dependent receptor( domain architecture ID 10102105)

TonB-dependent receptor may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0015891|GO:0015267|GO:0055085
PubMed:  12409204

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 55-851 1.64e-61

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


:

Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 220.02  E-value: 1.64e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  55 PVVSVSKAQIEQSGQQTVADYLKQASYNSFGGYSPSSGDSYQsqgtvgLRGLGSTRTLVLLNGKRIAGSPtmGGTSINLN 134
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGGSTIS------IRGFGPDRTLVLVDGLPLASSN--YGRGVDLN 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 135 TIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGFE--GLTFQGRIGSPTEEGGDEQSGSIVSGITGDKGSLMMVYe 212
Cdd:cd01347    73 TIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDefGGSVTAGYGSDNSGSSGGGGFDVSGALADDGAFGARLY- 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 213 hdvkdvIYYKDRDylakqgaeapsiygrnikgvdattgktvtrtldgidcantgagfvpvgtacRFDFAQIAAKTASRTR 292
Cdd:cd01347   152 ------GAYRDGD---------------------------------------------------GTIDGDGQADDSDEER 174

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 293 DTVYVNGRYHINDNVDFVPQLIGSRVTSFGRFAPAAGAFTVDGSTPesaAVLSANNFSTAKAATVYYRFNNVGPRDNDVT 372
Cdd:cd01347   175 YNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGG---GPSSNTNGDRDWDYRDRYRKRASLGLEHDLN 251

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 373 DmtgnmnlgfegtvpteAVGDLEWNAGYMYSKTDNRSNGSGYVLEPAVQTQVNSGkfingsfsdaatkdlsydTSRTSKM 452
Cdd:cd01347   252 D----------------TGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSG------------------YSSERDT 297

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 453 DFFQWYGGLGwemGELPAGPVSWYL--GAEYndwvYSDTYDsqseagnvlgssgnsgsgvRDVFATYIESLIPITEQIEL 530
Cdd:cd01347   298 TQLGFDAGLN---APFGTGPVAHTLtlGVEY----RREELD-------------------EKQTALYAQDTIELTDDLTL 351

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 531 NLAGRYDKY--------------SDFGSAFSPKASLRYQPLDQLMFRTSWSQSFRAPGLDDLYaadsfsadFAKDYVGCQ 596
Cdd:cd01347   352 TLGLRYDHYdqdskdtiaggttaKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY--------GGGSHGGTA 423

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 597 ANGiancseaqydttrkaNKNLKEETANTFTIGAAYNPLDNLNLSLDYYYIKIDDVIQLATTqtqfyqelntgsnpnvir 676
Cdd:cd01347   424 AVG---------------NPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPT------------------ 470

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 677 danGDVEMVYAGMVNLGQLKTSGIDFKADYKydfnfFTMRYDFGGTYILKYEEGLFAGGPMIDKKGWNAlPDLRFNSGIG 756
Cdd:cd01347   471 ---NTGLGLVTVYVNGGKARIRGVELEASYD-----LTDGLGLTGSYTYTDTEVKRTDGATTGNRLPGI-PKHTANLGLD 541

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 757 ANFPqWWNLDAYLSANYIDSQSQDYVNGQEEGHIASNTVWNLNVAVDTGWNAKIQTGVKNMFNRGPSLSSDGFTYEEDLY 836
Cdd:cd01347   542 YELP-DEGLTAGGGVRYRGKQYADTANGNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSVRGSGLYGY 620

                         810
                  ....*....|....*
gi 1752263663 837 GIDGRIYYIDYTQKF 851
Cdd:cd01347   621 YGPGRTYYLSVSYKF 635
 
Name Accession Description Interval E-value
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 55-851 1.64e-61

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 220.02  E-value: 1.64e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  55 PVVSVSKAQIEQSGQQTVADYLKQASYNSFGGYSPSSGDSYQsqgtvgLRGLGSTRTLVLLNGKRIAGSPtmGGTSINLN 134
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGGSTIS------IRGFGPDRTLVLVDGLPLASSN--YGRGVDLN 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 135 TIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGFE--GLTFQGRIGSPTEEGGDEQSGSIVSGITGDKGSLMMVYe 212
Cdd:cd01347    73 TIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDefGGSVTAGYGSDNSGSSGGGGFDVSGALADDGAFGARLY- 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 213 hdvkdvIYYKDRDylakqgaeapsiygrnikgvdattgktvtrtldgidcantgagfvpvgtacRFDFAQIAAKTASRTR 292
Cdd:cd01347   152 ------GAYRDGD---------------------------------------------------GTIDGDGQADDSDEER 174

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 293 DTVYVNGRYHINDNVDFVPQLIGSRVTSFGRFAPAAGAFTVDGSTPesaAVLSANNFSTAKAATVYYRFNNVGPRDNDVT 372
Cdd:cd01347   175 YNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGG---GPSSNTNGDRDWDYRDRYRKRASLGLEHDLN 251

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 373 DmtgnmnlgfegtvpteAVGDLEWNAGYMYSKTDNRSNGSGYVLEPAVQTQVNSGkfingsfsdaatkdlsydTSRTSKM 452
Cdd:cd01347   252 D----------------TGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSG------------------YSSERDT 297

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 453 DFFQWYGGLGwemGELPAGPVSWYL--GAEYndwvYSDTYDsqseagnvlgssgnsgsgvRDVFATYIESLIPITEQIEL 530
Cdd:cd01347   298 TQLGFDAGLN---APFGTGPVAHTLtlGVEY----RREELD-------------------EKQTALYAQDTIELTDDLTL 351

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 531 NLAGRYDKY--------------SDFGSAFSPKASLRYQPLDQLMFRTSWSQSFRAPGLDDLYaadsfsadFAKDYVGCQ 596
Cdd:cd01347   352 TLGLRYDHYdqdskdtiaggttaKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY--------GGGSHGGTA 423

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 597 ANGiancseaqydttrkaNKNLKEETANTFTIGAAYNPLDNLNLSLDYYYIKIDDVIQLATTqtqfyqelntgsnpnvir 676
Cdd:cd01347   424 AVG---------------NPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPT------------------ 470

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 677 danGDVEMVYAGMVNLGQLKTSGIDFKADYKydfnfFTMRYDFGGTYILKYEEGLFAGGPMIDKKGWNAlPDLRFNSGIG 756
Cdd:cd01347   471 ---NTGLGLVTVYVNGGKARIRGVELEASYD-----LTDGLGLTGSYTYTDTEVKRTDGATTGNRLPGI-PKHTANLGLD 541

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 757 ANFPqWWNLDAYLSANYIDSQSQDYVNGQEEGHIASNTVWNLNVAVDTGWNAKIQTGVKNMFNRGPSLSSDGFTYEEDLY 836
Cdd:cd01347   542 YELP-DEGLTAGGGVRYRGKQYADTANGNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSVRGSGLYGY 620

                         810
                  ....*....|....*
gi 1752263663 837 GIDGRIYYIDYTQKF 851
Cdd:cd01347   621 YGPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 32-801 1.01e-59

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 214.34  E-value: 1.01e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  32 VEKLQKIKVTGSRISRVDVEGATPVVSVSKAQIEQSGQQTVADYLKQASynsfgGYSPSSGDSYQSQGTVGLRGLGSTRT 111
Cdd:COG4771    24 ATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLP-----GVSVTRSGGRGGSSGISIRGLGGDRV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 112 LVLLNGKRIAGSPTMGGTsiNLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGFEGLTFQGRIGSPTEEGGDE 191
Cdd:COG4771    99 LVLIDGVPVNNPALGGGG--DLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELEGSVSLGYGSNGNGTY 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 192 QSGSIVSGiTGDKGSLMMVYEhdvkdviyYKDRDYLAkqgaeapsiygrnikgvDATTGKTVTRTldgidcantgagfvp 271
Cdd:COG4771   177 SGSLSLGG-PGDKLSFLLSGS--------YRDRDGYL-----------------DYRNGGFVGNS--------------- 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 272 vgtacrfdfaqiaaktaSRTRDTVYVNGRYHINDNVDFVPQLIGSRVTSFGRFAPAAGAFTVDgstpesaavlsannfst 351
Cdd:COG4771   216 -----------------GYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISS----------------- 261

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 352 akaatvyyrfNNVGPRDNDVTDmtGNMNLGFEGTVPteavGDLEWNAGYMYSKTDNRSNGSGYvlepavqtqvnsgkfin 431
Cdd:COG4771   262 ----------DNAGDRDTTTDR--GNYSLRYNGDLG----DNLDLSLYYSRTDRDSTNGSLGG----------------- 308

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 432 gsfsdaatkdlsyDTSRTSKMDFFQWYGGLGWEMgeLPAGPVSWYLGAEYNDwvysDTYDSQSEAGNvlgssgnsGSGVR 511
Cdd:COG4771   309 -------------STGSFSDSDDTTYGLELDLTY--PLGGNHTLTLGAEYRY----DDLDSSSFLGG--------ADASR 361

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 512 DVFATYIESLIPITEQIELNLAGRYDKYSDFG----SAFSPKASLRYQPLDQLMFRTSWSQSFRAPGLDDLYAADSFSad 587
Cdd:COG4771   362 DTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGT-- 439

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 588 fakdyvgcqangiancseaqYDTTRKANKNLKEETANTFTIGAAYNPLDN-LNLSLDYYYIKIDDVIQLATTqtqfyqel 666
Cdd:COG4771   440 --------------------PGRYVLGNPDLKPETSDNYELGLEYRLGNGgLSLSLTGFYTDIKDLIVLVPV-------- 491

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 667 nTGSNPNVIRdangdvemvyagMVNLGQLKTSGIDFKADYKYDFNFftmRYDFGGTYI-LKYEEGlfaggpmIDKKGWNA 745
Cdd:COG4771   492 -GPGPGDVLQ------------YENVGKARTYGLELELKYRLGKGL---TLTASYTYLdSKIDDG-------DTGEPLPN 548

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1752263663 746 LPDLRFNSGIGANFPQWWNLdaYLSANYIDSQSQDYVNGQEEGHIASNTVWNLNVA 801
Cdd:COG4771   549 VPPHKANLGLDYRLPKWWLL--LLLTRYYGGRYVTPPSGRLEGYTPGYTLLDLRAS 602
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 346-845 2.08e-33

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 134.90  E-value: 2.08e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 346 ANNFSTAKAATVYYRFNNVGPRDNDVTDMTGNMNLGFEGTVPTEAVGDLEWNAGYMYSKTDNRSNGSGYVLEPAVQTQVN 425
Cdd:pfam00593  31 GLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSD 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 426 SGKFINGSFSDAATKDLSYDtsrtskmdffqwygglgwemGELPAGPVSWYLGAEYNDwvysDTYDSQSEAGNVLGSSGN 505
Cdd:pfam00593 111 DRLYGLYGLDGDLELSLDLS--------------------HDLLLGVELRTAGLDYRR----LDDDAYDPYDPANPSSSS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 506 SGSGVRDVFATYIESLIPITEQIELNLAGRYDKYSDFG--------------SAFSPKASLRYQPLDQLMFRTSWSQSFR 571
Cdd:pfam00593 167 YSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGddgngggdnfsrsySAFSPRLGLVYKPTDNLSLYASYSRGFR 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 572 APGLDDLYAADSFSADFAKDYvgcqangiancseaqydttrkANKNLKEETANTFTIGAAYNPlDNLNLSLDYYYIKIDD 651
Cdd:pfam00593 247 APSLGELYGSGSGGGGGAVAG---------------------GNPDLKPETSDNYELGLKYDD-GRLSLSLALFYIDIKN 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 652 VIQLATTQTQFYQELNTgsnpnvirdangdvemvyagMVNLGQLKTSGIDFKADYkydfNFFTMRYDFGGtyiLKYEEGL 731
Cdd:pfam00593 305 LITSDPDGPGLGGTVYT--------------------YTNVGKARIRGVELELSG----RLWGLGLSGGG---YTYTDAD 357

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 732 FAGGPMIDKKGWNALPDLRFNSGIGANFPQwWNLDAYLSANYIDSQSQDYVNGQEEGHIASNTVWNLNVAVDTGWNAKIQ 811
Cdd:pfam00593 358 DDADADDTGNPLPNVPRHTANLGLTYDFPL-GGWGARLGARYVGSGERRYGDAANTFKTPGYTLVDLSAGYRLNKNLTLR 436

                         490       500       510
                  ....*....|....*....|....*....|....
gi 1752263663 812 TGVKNMFNRGPSLSSDGFTYEEDLYGIDGRIYYI 845
Cdd:pfam00593 437 LGVNNLFDKYYKRYYSSGGGNLGGYPGPGRTFYL 470
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
 35-820 1.66e-20

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 96.69  E-value: 1.66e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  35 LQKIKVTGSRISRVDVEGATPVVSVSKAQIEQSGQQTVADYLKQASynsfgGYSPSSGDSYQSQgTVGLRGLGSTRTLVL 114
Cdd:TIGR01785   1 LDTVTVTATRTRQVLSEAPASVSVISGEQIESKQANNLADALNTVP-----GVDVTGGGRPPGQ-SINIRGLQDNRVLVV 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 115 LNGKRIAGspTMGGTSINLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEgfegltfqgrigspteeggdeqsg 194
Cdd:TIGR01785  75 VDGARQNY--QRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKD------------------------ 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 195 sivsgitgdkgSLMMVYEHDVKDVIYYKDRDYLAKQGAEAPSIYGRNIKGVDATTGKTVT-----RTLDGIDCANTGagf 269
Cdd:TIGR01785 129 -----------AADLLRPGQLFGGLAKLSYGSNNNSFGGSVAVAGRLDDNLDALVAATYRdggnyRNGNKEEATNSA--- 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 270 vpvgtacrfdfaqiaaktasrtrdtvyvngryhiNDNVDFVPQLiGSRVTSFGRFApaAGAFTVDGSTPESAAVLSANNF 349
Cdd:TIGR01785 195 ----------------------------------YVQKNLLAKL-GWQLDDAQRLE--FSYFTTEGSLDEAQNSGPGTEY 237

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 350 STAKAATVYyrfnnvgprDNDVTDMTGNMNLGFegtvPTEAVGDLEWNAGYMYSKTDNRsngsgyvlepavQTQVNSGKF 429
Cdd:TIGR01785 238 VLGSSSTLL---------ASSTRDRSATLTYNW----TPEDNPWLDATASLYYNRTEND------------NDRSARGVG 292

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 430 INGSFSDAATKDLSYDTSRTSKMDFFQWYGGLgwemgelpagpvswylgaeynDWVYSDTYDSQSEAGNVLGSSGNSGSG 509
Cdd:TIGR01785 293 REEGYQYTTYGATLQNTSRFDVASWSTLTYGV---------------------DWMKDKRRTESFDPNSVTTIVPNPPSA 351

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 510 VRDVFATYIESLIPI-TEQIELNLAGRYDKYS------------DFG-SAFSPKASLRYQPLDQLMFRTSWSQSFRAPGL 575
Cdd:TIGR01785 352 KEYFFGLFLQDNIPLlDDRLTLSAGLRYDHYKlspkttadteavDRSySRWSPSLGLSYKPVDWLTLYASYSQGFRAPSI 431

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 576 DDLYAADSFSADfakdyvgcqanGIANCseaqydttRKANKNLKEETANTFTIGAAYNpLDNLNLSLD-------YYYIK 648
Cdd:TIGR01785 432 DELYGTGDHPGT-----------PGGYT--------FAPNPNLKPETSKTWELGANLS-FDNLLLDNDqlqfkvaYFYND 491

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 649 IDDVIQLATTQTQFyqeLNTGSNPnvirdangdvemvYAGMVNLGQLKTSGIDFKADYKYD--FNFFTMRYDFGGTyiLK 726
Cdd:TIGR01785 492 VKDFIDLTIGVTDN---VTAGMNN-------------ITQYVNIDGARIRGIEASASYDAGlwATGLSYGYTIGKD--QN 553

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 727 YEEGLfaggpmidkkgwNALPDLRFNSGIGANFPQwWNLDAYLSANYIDSQSQ-DYVNGQEEGHIA---SNTVWNL--NV 800
Cdd:TIGR01785 554 TNQWL------------SNIPPLKLVVTVGYRFPD-RRLDLGAKAAYYERQSEsPTTEDVAANGLLttpGYTVVDLyaTY 620

                         810       820
                  ....*....|....*....|
gi 1752263663 801 AVDTGWNAKIQTGVKNMFNR 820
Cdd:TIGR01785 621 QPNAVKGLTVRFGVNNLTDR 640
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 33-851 2.90e-17

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 86.48  E-value: 2.90e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  33 EKLQKIKVTGSRISrVDVEGATPVVSVSKAQ-IEQSGQQTVADYLKQASynsfGGYSPSSGDSYQsqgTVGLRGLGSTRT 111
Cdd:PRK10064   28 DDGETMVVTASAVE-QNLKDAPASISVITQEdLQRKPVQNLKDVLKEVP----GVQLTNEGDNRK---GVSIRGLDSSYT 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 112 LVLLNGKRI-AGSPTMGGTSINLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINVIlkegfegltfqgrigspTEEGGD 190
Cdd:PRK10064  100 LILIDGKRVnSRNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNII-----------------TKKIGQ 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 191 EQSGSIVSGITgdkgslmmVYEHdvkdviyyKDRdylakqgaeapsiyGRNIKGVDATTGKTVTRTLdgidcantgaGFV 270
Cdd:PRK10064  163 KWHGTVTVDTT--------IQEH--------RDR--------------GDTYNGQFFTSGPLIDGVL----------GMK 202

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 271 PVGTACRFDFAQIAAKTASRTRDTVYVNGRYHINDNVDFvpqligsrvtsfgrfapaagAFTVDGStpesaavlsaNNFS 350
Cdd:PRK10064  203 AYGSLAKREKDDPQNSTTTDTGETPRIEGFTSRDGNVEF--------------------AWTPNQN----------HDFT 252

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 351 TAkaatvyYRFNNvGPRDNDVTDMTG----NMNLGFEGtvpteavgdlEWNAG-----YMYSKTDNRSNGsgyvlepavQ 421
Cdd:PRK10064  253 AG------YGFDR-QDRDSDSLDKNRlerqNYSLSHNG----------RWDYGnselkYYGEKVENKNPG---------N 306

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 422 TQVNSgkfingsfSDAATKDLSYdtsrtskmdffqwygglgwemgELPAGPVSWYL--GAEYNdwvysdtYDSQSEAGNv 499
Cdd:PRK10064  307 SSPIT--------SESNSIDGKY----------------------TLPLTAINQFLtfGGEWR-------HDKLSDAVN- 348

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 500 LGSSGNSGSGVRDvFATYIESLIPITEQIELNLAGRYDKYSDFGSAFSPKASLRYQPLDQLMFRTSWSQSFRAPGLDDLy 579
Cdd:PRK10064  349 LTGGTSSKTSASQ-YALFVEDEWRIFEPLALTTGVRMDDHETYGDHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQL- 426

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 580 aadsfSADFakdyvgcqanGIANCSEAQYDTtrkANKNLKEETANTFTIGAAYNP----LDNLNLSLDYYYIKIDDVIQL 655
Cdd:PRK10064  427 -----SPDW----------TSNSCRGACKIV---GSPDLKPETSESWELGLYYMGeegwLEGVESSVTVFRNDVDDRISI 488

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 656 ATT----QTQFYQELnTGSNPnvirDANGDVEMVYAgMVNLGQLKTSGIDfkADYKYDFNfftMRYDFGGTYILKYEEGL 731
Cdd:PRK10064  489 SRTsdvnAAPGYQNF-VGFET----NGRGRRVPVFR-YYNVNKARIQGVE--TELKIPFN---DEWKLSLNYTYNDGRDV 557

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 732 FAGGpmiDKkgwnALPDLRFNSGIG-----ANFPQWWNLdaYLSANYIDSQSQDYVNGQEEGhiaSNTVWNLNVAVDTGW 806
Cdd:PRK10064  558 SNGE---NK----PLSDLPFHTANGtldwkPLALEDWSF--YVSGNYTGQKRADSATAKTPG---GYTIWNTGAAWQVTK 625

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....*
gi 1752263663 807 NAKIQTGVKNMFNRgpSLSSDGFTYEEdlygiDGRIYYIDYTQKF 851
Cdd:PRK10064  626 DVKLRAGVLNLGDK--DLSRDDYSYNE-----DGRRYFMAVDYRF 663
 
Name Accession Description Interval E-value
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 55-851 1.64e-61

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 220.02  E-value: 1.64e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  55 PVVSVSKAQIEQSGQQTVADYLKQASYNSFGGYSPSSGDSYQsqgtvgLRGLGSTRTLVLLNGKRIAGSPtmGGTSINLN 134
Cdd:cd01347     1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGGGGGSTIS------IRGFGPDRTLVLVDGLPLASSN--YGRGVDLN 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 135 TIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGFE--GLTFQGRIGSPTEEGGDEQSGSIVSGITGDKGSLMMVYe 212
Cdd:cd01347    73 TIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRPTDefGGSVTAGYGSDNSGSSGGGGFDVSGALADDGAFGARLY- 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 213 hdvkdvIYYKDRDylakqgaeapsiygrnikgvdattgktvtrtldgidcantgagfvpvgtacRFDFAQIAAKTASRTR 292
Cdd:cd01347   152 ------GAYRDGD---------------------------------------------------GTIDGDGQADDSDEER 174

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 293 DTVYVNGRYHINDNVDFVPQLIGSRVTSFGRFAPAAGAFTVDGSTPesaAVLSANNFSTAKAATVYYRFNNVGPRDNDVT 372
Cdd:cd01347   175 YNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGSSLGG---GPSSNTNGDRDWDYRDRYRKRASLGLEHDLN 251

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 373 DmtgnmnlgfegtvpteAVGDLEWNAGYMYSKTDNRSNGSGYVLEPAVQTQVNSGkfingsfsdaatkdlsydTSRTSKM 452
Cdd:cd01347   252 D----------------TGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSG------------------YSSERDT 297

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 453 DFFQWYGGLGwemGELPAGPVSWYL--GAEYndwvYSDTYDsqseagnvlgssgnsgsgvRDVFATYIESLIPITEQIEL 530
Cdd:cd01347   298 TQLGFDAGLN---APFGTGPVAHTLtlGVEY----RREELD-------------------EKQTALYAQDTIELTDDLTL 351

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 531 NLAGRYDKY--------------SDFGSAFSPKASLRYQPLDQLMFRTSWSQSFRAPGLDDLYaadsfsadFAKDYVGCQ 596
Cdd:cd01347   352 TLGLRYDHYdqdskdtiaggttaKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELY--------GGGSHGGTA 423

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 597 ANGiancseaqydttrkaNKNLKEETANTFTIGAAYNPLDNLNLSLDYYYIKIDDVIQLATTqtqfyqelntgsnpnvir 676
Cdd:cd01347   424 AVG---------------NPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVSTPT------------------ 470

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 677 danGDVEMVYAGMVNLGQLKTSGIDFKADYKydfnfFTMRYDFGGTYILKYEEGLFAGGPMIDKKGWNAlPDLRFNSGIG 756
Cdd:cd01347   471 ---NTGLGLVTVYVNGGKARIRGVELEASYD-----LTDGLGLTGSYTYTDTEVKRTDGATTGNRLPGI-PKHTANLGLD 541

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 757 ANFPqWWNLDAYLSANYIDSQSQDYVNGQEEGHIASNTVWNLNVAVDTGWNAKIQTGVKNMFNRGPSLSSDGFTYEEDLY 836
Cdd:cd01347   542 YELP-DEGLTAGGGVRYRGKQYADTANGNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNNLFDKDYYTSLSVRGSGLYGY 620

                         810
                  ....*....|....*
gi 1752263663 837 GIDGRIYYIDYTQKF 851
Cdd:cd01347   621 YGPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 32-801 1.01e-59

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 214.34  E-value: 1.01e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  32 VEKLQKIKVTGSRISRVDVEGATPVVSVSKAQIEQSGQQTVADYLKQASynsfgGYSPSSGDSYQSQGTVGLRGLGSTRT 111
Cdd:COG4771    24 ATELEEVVVTATRTEQSLSDAPASVSVITAEEIEKLGATDLADALRLLP-----GVSVTRSGGRGGSSGISIRGLGGDRV 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 112 LVLLNGKRIAGSPTMGGTsiNLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGFEGLTFQGRIGSPTEEGGDE 191
Cdd:COG4771    99 LVLIDGVPVNNPALGGGG--DLSYIPPDDIERIEVIRGPASALYGSDAIGGVINIITKKPTDELEGSVSLGYGSNGNGTY 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 192 QSGSIVSGiTGDKGSLMMVYEhdvkdviyYKDRDYLAkqgaeapsiygrnikgvDATTGKTVTRTldgidcantgagfvp 271
Cdd:COG4771   177 SGSLSLGG-PGDKLSFLLSGS--------YRDRDGYL-----------------DYRNGGFVGNS--------------- 215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 272 vgtacrfdfaqiaaktaSRTRDTVYVNGRYHINDNVDFVPQLIGSRVTSFGRFAPAAGAFTVDgstpesaavlsannfst 351
Cdd:COG4771   216 -----------------GYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISS----------------- 261

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 352 akaatvyyrfNNVGPRDNDVTDmtGNMNLGFEGTVPteavGDLEWNAGYMYSKTDNRSNGSGYvlepavqtqvnsgkfin 431
Cdd:COG4771   262 ----------DNAGDRDTTTDR--GNYSLRYNGDLG----DNLDLSLYYSRTDRDSTNGSLGG----------------- 308

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 432 gsfsdaatkdlsyDTSRTSKMDFFQWYGGLGWEMgeLPAGPVSWYLGAEYNDwvysDTYDSQSEAGNvlgssgnsGSGVR 511
Cdd:COG4771   309 -------------STGSFSDSDDTTYGLELDLTY--PLGGNHTLTLGAEYRY----DDLDSSSFLGG--------ADASR 361

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 512 DVFATYIESLIPITEQIELNLAGRYDKYSDFG----SAFSPKASLRYQPLDQLMFRTSWSQSFRAPGLDDLYAADSFSad 587
Cdd:COG4771   362 DTYGLFAQDEWKLTDKLTLTAGLRYDYYSTFGasnyTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLAELYGSGTGT-- 439

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 588 fakdyvgcqangiancseaqYDTTRKANKNLKEETANTFTIGAAYNPLDN-LNLSLDYYYIKIDDVIQLATTqtqfyqel 666
Cdd:COG4771   440 --------------------PGRYVLGNPDLKPETSDNYELGLEYRLGNGgLSLSLTGFYTDIKDLIVLVPV-------- 491

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 667 nTGSNPNVIRdangdvemvyagMVNLGQLKTSGIDFKADYKYDFNFftmRYDFGGTYI-LKYEEGlfaggpmIDKKGWNA 745
Cdd:COG4771   492 -GPGPGDVLQ------------YENVGKARTYGLELELKYRLGKGL---TLTASYTYLdSKIDDG-------DTGEPLPN 548

                         730       740       750       760       770
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1752263663 746 LPDLRFNSGIGANFPQWWNLdaYLSANYIDSQSQDYVNGQEEGHIASNTVWNLNVA 801
Cdd:COG4771   549 VPPHKANLGLDYRLPKWWLL--LLLTRYYGGRYVTPPSGRLEGYTPGYTLLDLRAS 602
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
35-836 2.79e-45

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 173.09  E-value: 2.79e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  35 LQKIKVTGSRISRVDVEGATPVVSVSKAQIEQSGQQTVADYLKQASynsfgGYSPSSGDSYQSQgtVGLRGLG--STRTL 112
Cdd:COG1629     1 LEEVVVTATRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVP-----GVSVTSAGGGAGQ--ISIRGFGggGNRVL 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 113 VLLNGKRIAGSPTMGGtsiNLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGFEGLTFQGRIGSpteEGGDEQ 192
Cdd:COG1629    74 VLVDGVPLNDPSGGDG---GLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASY---GSYGTY 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 193 SGSIVSGITGDKGSLMMVYEhdvkdviYYKDRDYLAKQGAEapsiygrnikgvdattgktvtrtldgidcantgagfvpv 272
Cdd:COG1629   148 RASLSLSGGNGKLAYRLSAS-------YRDSDGYRDNSDSD--------------------------------------- 181

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 273 gtacrfdfaqiaaktasrtRDTVYVNGRYHINDNVDFvpqligsrvtsfgrfapaagAFTVDGSTPESAAVLSANNFSTA 352
Cdd:COG1629   182 -------------------RYNLRAKLGYQLGDDTRL--------------------TLSASYSDSDQDSPGYLTLAALR 222

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 353 KAATVYYRFNNVGPRDNDVTDMTGNMNLGFEgtvPTEAVGDLEWNAGYMYSKTDNRSNGSGYVLEPAVQTQvnsgkfing 432
Cdd:COG1629   223 PRGAMDDGTNPYSNDTDDNTRDRYSLSLEYE---HLGDGLKLSASAYYRYDDTDLDSDFTPTPADGGTLEQ--------- 290

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 433 sfSDAATKDLSYDTSRTSKMDFfqwygglgwemgelpAGPVSWYLGAEY-NDWVYSDTYDSQSEAGNVLGSSGNSGSGVR 511
Cdd:COG1629   291 --TDFDNRTYGLELRLTYDLGF---------------GGKHTLLVGLDYqRQDLDGSGYPLDLGSGSLPTLTSGADDDGT 353

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 512 -DVFATYIESLIPITEQIELNLAGRYDKYSDFG----------------SAFSPKASLRYQPLDQLMFRTSWSQSFRAPG 574
Cdd:COG1629   354 tTSLALYAQDTYKLTDKLTLTAGLRYDYVSYDVddtvtgtdsasgsrsySAFSPSLGLTYQLSPNLSLYASYSRGFRAPT 433

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 575 LDDLYAadsfsadfakdyvgcqangiancseAQYDTTRKANKNLKEETANTFTIGAAYNPLDN-LNLSLDYYYIKIDDVI 653
Cdd:COG1629   434 FGELYA-------------------------NGTDPYSVGNPDLKPETSTNYELGLRYRLLDGrLSLSLALFYSDVDNEI 488

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 654 qlattqTQFYQELNTGSNPNVirdangdvemvyagmVNLGQLKTSGIDFKADYKYDFNFFTmryDFGGTYILKYEEGLFA 733
Cdd:COG1629   489 ------LSVPLPNDSGFSTYY---------------TNAGKARSYGVELELSYQLTPGLSL---NASYSYTDAKFDDDTD 544

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 734 GGPMIDKKGWNALPDLRFNSGIGANFPQWWnlDAYLSANYIDSQSQDYVNGQEegHIASNTVWNLNVAVDTGWNAKIQTG 813
Cdd:COG1629   545 GSADLDGNRLPGVPPLTANLGLTYEFPGGW--SLGLGVRYVGDRYLDDANTQG--APGGYTLVDLGAGYRFGDNLTLSLG 620

                         810       820
                  ....*....|....*....|...
gi 1752263663 814 VKNMFNRGPSLSSDGFTYEEDLY 836
Cdd:COG1629   621 VDNLFDKKYATSLSVRASNVRGF 643
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 346-845 2.08e-33

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 134.90  E-value: 2.08e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 346 ANNFSTAKAATVYYRFNNVGPRDNDVTDMTGNMNLGFEGTVPTEAVGDLEWNAGYMYSKTDNRSNGSGYVLEPAVQTQVN 425
Cdd:pfam00593  31 GLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSD 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 426 SGKFINGSFSDAATKDLSYDtsrtskmdffqwygglgwemGELPAGPVSWYLGAEYNDwvysDTYDSQSEAGNVLGSSGN 505
Cdd:pfam00593 111 DRLYGLYGLDGDLELSLDLS--------------------HDLLLGVELRTAGLDYRR----LDDDAYDPYDPANPSSSS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 506 SGSGVRDVFATYIESLIPITEQIELNLAGRYDKYSDFG--------------SAFSPKASLRYQPLDQLMFRTSWSQSFR 571
Cdd:pfam00593 167 YSDTTTDSYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGddgngggdnfsrsySAFSPRLGLVYKPTDNLSLYASYSRGFR 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 572 APGLDDLYAADSFSADFAKDYvgcqangiancseaqydttrkANKNLKEETANTFTIGAAYNPlDNLNLSLDYYYIKIDD 651
Cdd:pfam00593 247 APSLGELYGSGSGGGGGAVAG---------------------GNPDLKPETSDNYELGLKYDD-GRLSLSLALFYIDIKN 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 652 VIQLATTQTQFYQELNTgsnpnvirdangdvemvyagMVNLGQLKTSGIDFKADYkydfNFFTMRYDFGGtyiLKYEEGL 731
Cdd:pfam00593 305 LITSDPDGPGLGGTVYT--------------------YTNVGKARIRGVELELSG----RLWGLGLSGGG---YTYTDAD 357

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 732 FAGGPMIDKKGWNALPDLRFNSGIGANFPQwWNLDAYLSANYIDSQSQDYVNGQEEGHIASNTVWNLNVAVDTGWNAKIQ 811
Cdd:pfam00593 358 DDADADDTGNPLPNVPRHTANLGLTYDFPL-GGWGARLGARYVGSGERRYGDAANTFKTPGYTLVDLSAGYRLNKNLTLR 436

                         490       500       510
                  ....*....|....*....|....*....|....
gi 1752263663 812 TGVKNMFNRGPSLSSDGFTYEEDLYGIDGRIYYI 845
Cdd:pfam00593 437 LGVNNLFDKYYKRYYSSGGGNLGGYPGPGRTFYL 470
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
40-323 6.74e-28

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 114.20  E-value: 6.74e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  40 VTGSRISRVDVEGATPVVSVSKAQIEQSGQQTVADYLKQASynsfgGYSPSSGDSYQSQGTVGLRGLGSTRTLVLLNGKR 119
Cdd:COG4206     3 VTATRLEQSKSDLTGSVTVIDAEELERSGATSLADALRRVP-----GVQVSSSGGPGSAASISIRGLGSNQTLVLIDGVP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 120 IaGSPTMGGTsiNLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGFEG--LTFQGRIGSpteegGDEQSGSIV 197
Cdd:COG4206    78 L-NDPSLGGV--DLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGfkGSVSASYGS-----FGTRRLSAS 149

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 198 SGITGDKGSLMMVYEHDVKDVIYYKDRDYLAKQGAEAPSIYGRNikGVDATTGKTVTRTLDGIDcanTGAGFVPVGTACR 277
Cdd:COG4206   150 LSGGAGKFSYSLSASYRRSDGYRYNDPDLRNNDGYENTSLNARL--GYKLGDNGSLSLSGGYSD---SERGYPGAVGSDR 224

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 1752263663 278 FDFAQIAAKTASRTRDTVYVNGRYHINDNVDFVPQLIGSRVTSFGR 323
Cdd:COG4206   225 NLRLSLSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGA 270
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
22-820 9.86e-22

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 100.77  E-value: 9.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  22 PSVSAEEGQNVEKLQKIKVTGSRISRVDVEgATP--VVSVSKAQIEQSGQQTVADYLKQA----SYNSFGgyspsSGDsy 95
Cdd:COG4772    10 LLAAAAAAEAATTLETVVVTGSRAAEARLK-DVPgsVSVVDREELENQAATSLREVLRRVpgvnVQEEDG-----FGL-- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  96 qsQGTVGLRGLGSTRT---LVLLNGKRIAGSPTMGGTSINLNtiPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGF 172
Cdd:COG4772    82 --RPNIGIRGLGPRRSrgiTLLEDGIPIAPAPYGDPAAYYFP--DLERMERIEVLRGAAALRYGPQTVGGAINFVTRTIP 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 173 EGLTFQGRIgspteEGG--DEQSGSIVSGITGDKGSLMMVYEHDVKDviYYKDrdylakqgaeapsiygrnikgvdattg 250
Cdd:COG4772   158 TAFGGELRV-----TGGsfGYRRTHASVGGTVGNFGYLVEYSRKRGD--GFRD--------------------------- 203

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 251 ktvtrtldgidcaNTGAgfvpvgtacrfdfaqiaaktasrTRDTVYVNGRYHINDNVDFVPQLIGSRVTSfgrfapaaga 330
Cdd:COG4772   204 -------------NSGF-----------------------DINDFNAKLGYRLSDRQELTLKFQYYDEDA---------- 237

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 331 ftvD---GSTPESAAvlsANnfstakaatvyyRFNNVGPRDNDVTDMTGnmnLGFEGTVPTEAVGDLEWNAGYMYSKTD- 406
Cdd:COG4772   238 ---NtpgGLTDAQFD---AD------------PRQSYRPADQFDTRRTQ---LSLRYEHQLSDNTTLTTTAYYNDFSRNw 296

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 407 -NRSNGSGYVLePAVQTQVNSGKFINGSFSdaatkdlsydtSRtskmdfFQWYGGLGWEMGELPAGpvSWYLGAEYNDWV 485
Cdd:COG4772   297 yIRQNTADPNT-PGLGLRGNPRGYRSYGIE-----------PR------LTHRFELGGVPHTLEVG--LRYHREEEDRKQ 356

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 486 YSDTYDsQSEAGNVLGSSGNSGSgvrDVFATYIESLIPITEQIELNLAGRYD----KYSDFG--------------SAFS 547
Cdd:COG4772   357 YVNTYG-QGRSGAGLRRDRRFSA---DALAAYAQNRFELTGRLTLTPGLRYEhirrDRTDRYstrtggddsgsnsySEFL 432

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 548 PKASLRYQPLDQLMFRTSWSQSFRAPGLDDLYAADSFsadfakdyvgcqangiancseaqydttrkaNKNLKEETANTFT 627
Cdd:COG4772   433 PGLGLLYQLTDNLQLYANVSRGFEPPTFGDLAYGNGG------------------------------NPDLKPEKSWNYE 482

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 628 IGAAYNPLDNLNLSLDYYYIKIDDviqlattqtqfyqELNTGSNPNVIRDANgdvemvyagmVNLGQLKTSGIDFKADYK 707
Cdd:COG4772   483 LGTRGRIGNGLSAEVALFYIDYDN-------------ELGSCSAAGGDRSTF----------TNAGETRHQGLELALDYD 539

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 708 -YDFNFFTMRYDFGGTY----ILKYEEGLFAGgpmidkkgwNAL---PDLRFNSGIGANFPQWwnlDAYLSANYIDSQSQ 779
Cdd:COG4772   540 lLKGGGLGLPLFAAYTYtdaeFTSDFGPVFAG---------NRLpyvPRHQLTAGLGYEHGGW---TANLNGRYVSEQFT 607

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....
gi 1752263663 780 DYVNGQEEGH---IASNTVWNLNVAVDTGWNAKIQTGVKNMFNR 820
Cdd:COG4772   608 DAANTVADGSfgkIPSYTVLDLSASYDFGKNLSLFAGVNNLFDK 651
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
 35-820 1.66e-20

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 96.69  E-value: 1.66e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  35 LQKIKVTGSRISRVDVEGATPVVSVSKAQIEQSGQQTVADYLKQASynsfgGYSPSSGDSYQSQgTVGLRGLGSTRTLVL 114
Cdd:TIGR01785   1 LDTVTVTATRTRQVLSEAPASVSVISGEQIESKQANNLADALNTVP-----GVDVTGGGRPPGQ-SINIRGLQDNRVLVV 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 115 LNGKRIAGspTMGGTSINLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEgfegltfqgrigspteeggdeqsg 194
Cdd:TIGR01785  75 VDGARQNY--QRGGAHNGSLFVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKD------------------------ 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 195 sivsgitgdkgSLMMVYEHDVKDVIYYKDRDYLAKQGAEAPSIYGRNIKGVDATTGKTVT-----RTLDGIDCANTGagf 269
Cdd:TIGR01785 129 -----------AADLLRPGQLFGGLAKLSYGSNNNSFGGSVAVAGRLDDNLDALVAATYRdggnyRNGNKEEATNSA--- 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 270 vpvgtacrfdfaqiaaktasrtrdtvyvngryhiNDNVDFVPQLiGSRVTSFGRFApaAGAFTVDGSTPESAAVLSANNF 349
Cdd:TIGR01785 195 ----------------------------------YVQKNLLAKL-GWQLDDAQRLE--FSYFTTEGSLDEAQNSGPGTEY 237

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 350 STAKAATVYyrfnnvgprDNDVTDMTGNMNLGFegtvPTEAVGDLEWNAGYMYSKTDNRsngsgyvlepavQTQVNSGKF 429
Cdd:TIGR01785 238 VLGSSSTLL---------ASSTRDRSATLTYNW----TPEDNPWLDATASLYYNRTEND------------NDRSARGVG 292

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 430 INGSFSDAATKDLSYDTSRTSKMDFFQWYGGLgwemgelpagpvswylgaeynDWVYSDTYDSQSEAGNVLGSSGNSGSG 509
Cdd:TIGR01785 293 REEGYQYTTYGATLQNTSRFDVASWSTLTYGV---------------------DWMKDKRRTESFDPNSVTTIVPNPPSA 351

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 510 VRDVFATYIESLIPI-TEQIELNLAGRYDKYS------------DFG-SAFSPKASLRYQPLDQLMFRTSWSQSFRAPGL 575
Cdd:TIGR01785 352 KEYFFGLFLQDNIPLlDDRLTLSAGLRYDHYKlspkttadteavDRSySRWSPSLGLSYKPVDWLTLYASYSQGFRAPSI 431

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 576 DDLYAADSFSADfakdyvgcqanGIANCseaqydttRKANKNLKEETANTFTIGAAYNpLDNLNLSLD-------YYYIK 648
Cdd:TIGR01785 432 DELYGTGDHPGT-----------PGGYT--------FAPNPNLKPETSKTWELGANLS-FDNLLLDNDqlqfkvaYFYND 491

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 649 IDDVIQLATTQTQFyqeLNTGSNPnvirdangdvemvYAGMVNLGQLKTSGIDFKADYKYD--FNFFTMRYDFGGTyiLK 726
Cdd:TIGR01785 492 VKDFIDLTIGVTDN---VTAGMNN-------------ITQYVNIDGARIRGIEASASYDAGlwATGLSYGYTIGKD--QN 553

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 727 YEEGLfaggpmidkkgwNALPDLRFNSGIGANFPQwWNLDAYLSANYIDSQSQ-DYVNGQEEGHIA---SNTVWNL--NV 800
Cdd:TIGR01785 554 TNQWL------------SNIPPLKLVVTVGYRFPD-RRLDLGAKAAYYERQSEsPTTEDVAANGLLttpGYTVVDLyaTY 620

                         810       820
                  ....*....|....*....|
gi 1752263663 801 AVDTGWNAKIQTGVKNMFNR 820
Cdd:TIGR01785 621 QPNAVKGLTVRFGVNNLTDR 640
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 51-163 5.54e-20

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 85.78  E-value: 5.54e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  51 EGATPVVSVSKAQIEQSGQQTVADYLKQASynsfGGYSPSSGDSYQSQgtVGLRGLGSTRTLVLLNGKRIAGSptmGGTS 130
Cdd:pfam07715   4 DTPGSVSVVTAEDIEDQGATNLADALRGVP----GVSVSSGGGGGGSS--ISIRGFGSNRVLVLVDGVPLNSG---GGGS 74

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1752263663 131 INLNTIPMAAVERVEVNLDGGSALYGSDAIGGV 163
Cdd:pfam07715  75 VDLNSIDPEDIERVEVLKGPASALYGSGAIGGV 107
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
 36-820 4.48e-19

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 92.48  E-value: 4.48e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  36 QKIKVTGSRISRVDVEGATP----VVSVSKAQIEQSGQQTVADYLKQASynsfGGYSPSSGDSYQSqgTVGLRGLGSTRT 111
Cdd:TIGR01786   1 DTITVTATRTADPQRRDLSVtpasVSVISREQLKSQQVRNLRDLLRYEP----GVSVVEGGRGGSQ--GINIRGLDKNRV 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 112 LVLLNGKRIAGSPT-MGGTSINLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINV-------ILKEGfEGLTFQGRIGS 183
Cdd:TIGR01786  75 AVLVDGIRQNTSYGgQGSTFYAINSIDPELIKSIEIVKGASSSLYGSGALGGVVAFrtkdaadLLKPG-KDLGGLSKLGY 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 184 PTEEGGDEQSGSiVSGITGDKGSLMMVYEHDVKDVIYYKDR--DYLAKQGAEAPSIYGRN---IK-GVDATTGKTVTRTL 257
Cdd:TIGR01786 154 SSANNRFTQSVA-AAGRNDDVDALVQATYRRGHELKNGNKAniGNESKRSKPNPSDYKSQsflAKlGWQLNDAHRLGLSL 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 258 DGIDCANTGAGFVPVGTACRFDFAQIAAKTASRTRDTVYVNgRYHINDNVdfvpqligsrvtsfgrfapaagaftvdgsT 337
Cdd:TIGR01786 233 EYTQTDYDEPEMTNTSYLTKPLGAPLLSSTVVLGDSKTRDR-RTGLDYEL-----------------------------N 282

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 338 PESAAVLSANNFSTAKAATVYYRFNNVGPRDNDVTDMTGNmnlgfegtvpteavgdlewnagymysktdnRSNGSGYvle 417
Cdd:TIGR01786 283 PDNSWLDTVKLALDKQYIQLYNYLNATSASDYPGVDKNGR------------------------------YKDKYDY--- 329

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 418 pavqtqvnsgkfINGSFSDAATKDLSYDT-SRTSKMDFFqwygglgwemgelpagpvswylgaeYNDWVYSDTYDSQSEA 496
Cdd:TIGR01786 330 ------------YTLGFDTNNKIEFSVHSlSLTYGLDRF-------------------------KDKVSTGDSRRNLPTA 372

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 497 GNVLGSSGNSGSGVRDV-FATYIESLIPITEQIELNLAGRYDKY---------------SDFGSAFSPKASLRYQPLDQL 560
Cdd:TIGR01786 373 AYNLYGYEGENRPVKGSnFGLFLQDNIKLGDWLSLSAGLRYDHYktdpkadeskdygaiSKTYSRWSPSLGLTYKPTPWL 452

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 561 MFRTSWSQSFRAPGLDDLYAADSFSadfakdyvgcqangiancseAQYDTTRKANKNLKEETANTFTIGAAYNpLDNLNL 640
Cdd:TIGR01786 453 TLYYSYSQGFRAPSFDELYGTGAHP--------------------GGGPYTFLPNPNLKPETSKNWEIGINLH-FDQLDF 511

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 641 SLDYYYIKIDDVIQLATTQTQFYQELNTGSnpnvirdangdveMVYAGMVNLGQLKTSGIDFKADYKYDfNFFTMRYDFG 720
Cdd:TIGR01786 512 KVSYFRNDYKDFIDLGIGVTAKGNMAQVGS-------------NTITNYVNIDNARIRGIELSGRYDLG-SFFSGPDGWT 577

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 721 GTYILKYEEG-LFAGGPMidkkgWNALPDLRFNSGIGANFP-QWWNLDA---YLSANYIDSQSQDYVNGQEEGHIASN-- 793
Cdd:TIGR01786 578 TTLKYGYTKGkDSDTNPW-----LNAITPLKVVLGLGYDHPdEKWGVGLtltFSGAKDAVDAYATYYENGEAAKAGPLrt 652

                         810       820       830
                  ....*....|....*....|....*....|
gi 1752263663 794 ---TVWNLNVAVDTGWNAKIQTGVKNMFNR 820
Cdd:TIGR01786 653 psyTVVDLYGYYKPNKNLTLRFGVYNLLDR 682
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 33-851 2.90e-17

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 86.48  E-value: 2.90e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  33 EKLQKIKVTGSRISrVDVEGATPVVSVSKAQ-IEQSGQQTVADYLKQASynsfGGYSPSSGDSYQsqgTVGLRGLGSTRT 111
Cdd:PRK10064   28 DDGETMVVTASAVE-QNLKDAPASISVITQEdLQRKPVQNLKDVLKEVP----GVQLTNEGDNRK---GVSIRGLDSSYT 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 112 LVLLNGKRI-AGSPTMGGTSINLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINVIlkegfegltfqgrigspTEEGGD 190
Cdd:PRK10064  100 LILIDGKRVnSRNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNII-----------------TKKIGQ 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 191 EQSGSIVSGITgdkgslmmVYEHdvkdviyyKDRdylakqgaeapsiyGRNIKGVDATTGKTVTRTLdgidcantgaGFV 270
Cdd:PRK10064  163 KWHGTVTVDTT--------IQEH--------RDR--------------GDTYNGQFFTSGPLIDGVL----------GMK 202

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 271 PVGTACRFDFAQIAAKTASRTRDTVYVNGRYHINDNVDFvpqligsrvtsfgrfapaagAFTVDGStpesaavlsaNNFS 350
Cdd:PRK10064  203 AYGSLAKREKDDPQNSTTTDTGETPRIEGFTSRDGNVEF--------------------AWTPNQN----------HDFT 252

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 351 TAkaatvyYRFNNvGPRDNDVTDMTG----NMNLGFEGtvpteavgdlEWNAG-----YMYSKTDNRSNGsgyvlepavQ 421
Cdd:PRK10064  253 AG------YGFDR-QDRDSDSLDKNRlerqNYSLSHNG----------RWDYGnselkYYGEKVENKNPG---------N 306

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 422 TQVNSgkfingsfSDAATKDLSYdtsrtskmdffqwygglgwemgELPAGPVSWYL--GAEYNdwvysdtYDSQSEAGNv 499
Cdd:PRK10064  307 SSPIT--------SESNSIDGKY----------------------TLPLTAINQFLtfGGEWR-------HDKLSDAVN- 348

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 500 LGSSGNSGSGVRDvFATYIESLIPITEQIELNLAGRYDKYSDFGSAFSPKASLRYQPLDQLMFRTSWSQSFRAPGLDDLy 579
Cdd:PRK10064  349 LTGGTSSKTSASQ-YALFVEDEWRIFEPLALTTGVRMDDHETYGDHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQL- 426

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 580 aadsfSADFakdyvgcqanGIANCSEAQYDTtrkANKNLKEETANTFTIGAAYNP----LDNLNLSLDYYYIKIDDVIQL 655
Cdd:PRK10064  427 -----SPDW----------TSNSCRGACKIV---GSPDLKPETSESWELGLYYMGeegwLEGVESSVTVFRNDVDDRISI 488

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 656 ATT----QTQFYQELnTGSNPnvirDANGDVEMVYAgMVNLGQLKTSGIDfkADYKYDFNfftMRYDFGGTYILKYEEGL 731
Cdd:PRK10064  489 SRTsdvnAAPGYQNF-VGFET----NGRGRRVPVFR-YYNVNKARIQGVE--TELKIPFN---DEWKLSLNYTYNDGRDV 557

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 732 FAGGpmiDKkgwnALPDLRFNSGIG-----ANFPQWWNLdaYLSANYIDSQSQDYVNGQEEGhiaSNTVWNLNVAVDTGW 806
Cdd:PRK10064  558 SNGE---NK----PLSDLPFHTANGtldwkPLALEDWSF--YVSGNYTGQKRADSATAKTPG---GYTIWNTGAAWQVTK 625

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....*
gi 1752263663 807 NAKIQTGVKNMFNRgpSLSSDGFTYEEdlygiDGRIYYIDYTQKF 851
Cdd:PRK10064  626 DVKLRAGVLNLGDK--DLSRDDYSYNE-----DGRRYFMAVDYRF 663
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 49-851 3.23e-16

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 83.23  E-value: 3.23e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  49 DVEGATPVVSvsKAQIEQSGQQTVADYLKQASyNSFGGYSPSSGDSyqsqGTVGLRGLGSTrtlVLLNGKRIAGSPTMGg 128
Cdd:TIGR01783   1 DIPQSVSVIT--RQELEDQQAGSLSEALQRVP-GVVVGGSGGTTQF----GNITIRGFGLE---VDIDNVYLDGVPLLS- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 129 tSINLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGfeGLTFQGRIGSPTEEGGDEQSGSIVSGITGDKGSLm 208
Cdd:TIGR01783  70 -RGNLAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRP--QDEPKGSVTFGAGTRSGYRTAFDLGGPLGADGTF- 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 209 mvyehDVKDVIYYKDRDylakqgaeapsiygrnikgvdattgktvtrtlDGIDCANTGAGFVpvgtacrfdfaqiaAKTA 288
Cdd:TIGR01783 146 -----RGRLNGARQDGD--------------------------------SFYDGAGEETRLG--------------ATAT 174

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 289 SRTRDTVYvngryhindNVDFVPQLIGSRVTSFGRFAPAAGafTVDGSTPESAAVLSANNF-------STAKAATVYYRF 361
Cdd:TIGR01783 175 DWQLDDRT---------LLRLGAYYQKERDRGGYGGLPASG--GTSGRDLSSDRYLGTSSNrnyddreYLSYGLSLEYQF 243

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 362 NNVgprdndvtdMTGNMNLGFEgtvPTEAvgDLEWNAGYMYSKTDNRSNGSGYVL-EPAVQTQVNSGkfINGSFS-DAAT 439
Cdd:TIGR01783 244 NDV---------WTGKQNLRYS---YFDT--DSNQVQASGYSSDGGLFGRSLTVVnVKQDRVQIDAG--LDGEFEtGPIE 307

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 440 KDLSYDTSrtSKMDFFQWYGGLGwemgelpagpvswylgaEYNDWVYSDTYDSQSEAGNVLGSSGNSGSGVRDVFATYIE 519
Cdd:TIGR01783 308 HDLLLGVS--YGQRTTNRFNNTG-----------------YPSDNIYSLTATSSARTDIGDSPKDRALSSTTKALNGVAL 368

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 520 SLIPITEQIELNLAGRYDK-------------YSDFGSAFSPKASLRYQPLDQLMFRTSWSQSFRAPGlddlyaadsfsa 586
Cdd:TIGR01783 369 QRILLADKWTLTLGGRYDSvdvksnngvagstGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPGG------------ 436

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 587 dfakDYVGCQANGiancseaqydttrkaNKNLKEETANTFTIGAAYNPLDNLNLSLDYYYIKIDDVIQlattqtqfyqel 666
Cdd:TIGR01783 437 ----YYPKGAGNS---------------GDILEPEKGKNYELGVRYDLGDSLLATAALFRITKDNQLV------------ 485

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 667 nTGSNPNVIrdangdvemvyagMVNLGQLKTSGIDFKADYKYDFNfftMRYDFGGTYI-LKYEEGlfaggpmiDKKGWNA 745
Cdd:TIGR01783 486 -QDPVNGTF-------------SVNAGKTRNRGVELEARGYLTPG---LSLSAGYTYTdAEFTED--------TNGDTQG 540

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 746 -----LPDLRFNSGIGANFPQWWN-LDAYLSANYIDSQsqdYVNGQEEGHIASNTVWNLNVAVDTGWNAK--IQTGVKNM 817
Cdd:TIGR01783 541 ntvpfVPKHTASLWASYAPPVGDNgLTLGGGVQYTGKA---YVDGGNTGKVPSYTVVDLSVRYDLTKKKNltLALNVNNL 617

                         810       820       830
                  ....*....|....*....|....*....|....*
gi 1752263663 818 FNRG-PSLSSDGFTYEEDLYGiDGRIYYIDYTQKF 851
Cdd:TIGR01783 618 FDRDyYTSGYRWGPSAYIYPG-APRTVGLSVSYDF 651
PRK13483 PRK13483
ligand-gated channel protein;
101-851 1.26e-15

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 81.36  E-value: 1.26e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 101 VGLRGLGSTRTLVLLNGKRIAG---SPTMGGTSINLN-TIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGFEGLT 176
Cdd:PRK13483   91 ISLRGMGSQYTLILVDGKRQSSretRPNSDGPGVEQAwTPPLAAIERIEVIRGPMSSLYGSDAIGGVINIITRKVPNEWQ 170

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 177 FQGRIGSPTEE---GGDEQSGSI-VSGITGDKGSLMMVY---EHDVKDVIYYKDRDYLAkQGAEAPSIY----------- 238
Cdd:PRK13483  171 GEVRLDTTLQEnsdSGNVYQANFfVNGPLIKDLLGLQLYgqyTQREEDDIEGGYRDKDA-RSLTAKLALtpnedhdimle 249

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 239 -GRNIKGVDATTGKTVTRTLDGIDCANTGagfvpvgtacrfdfaqiaaktasrtrdtvyvngryhindnvdfvpqligsr 317
Cdd:PRK13483  250 vGTSNQERDSTVGKTVAPLAPGESCGRRG--------------------------------------------------- 278

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 318 vtsfgrfapaagaftvdgsTPESaavlsannfstakaATVYYRFNNVGprdndvTDMTGNMNLGFEGTvpteavgdlewn 397
Cdd:PRK13483  279 -------------------CPES--------------STTEYERSTVS------LSHTGRWDFGTSDT------------ 307

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 398 agYM-YSKTDNRSNgsgyvlepavqtqvnsgkfingsfsDAATKDLSYDTSrtskmdffqWYGGLGWEMgelpagpvSWY 476
Cdd:PRK13483  308 --YIqHEEFDNKSR-------------------------EMKIKNTDFQSS---------LVAPLGQEH--------TLT 343

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 477 LGAEYNDWVYSDtydsqsEAGNVLGSSGNSGsgvRDVFATYIESLIPITEQIELNLAGRYDKYSDFGSAFSPKASLRYQP 556
Cdd:PRK13483  344 FGAAYNHQDLTD------ETSNQISDLTDIS---RTQWAVFSEDEWRIADDFALTGGLRLDHDENFGGHVSPRVYGVWNL 414

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 557 LDQLMFRTSWSQSFRAPGLDDLyaadsfSADFAKDYVGCQANGiancseaqydttrkaNKNLKEETANTFTIGAAYNPLD 636
Cdd:PRK13483  415 APSWTVKGGVSTGFRAPSLRQT------TPDWGQVSRGGNIYG---------------NPDLKPETSLNKELGLYYDLGS 473

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 637 NLNLSLDYYYIKIDDVI-QLATTQTQFYQELNT-GSNPNVirdangdvemvyagMVNLGQLKTSGIDFKADYKydfnfFT 714
Cdd:PRK13483  474 GLTASLTVFYNEFKDKItRVACPATQCTDGPNQfGADPTT--------------YVNIDEAVTQGVEASLSYP-----IT 534

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 715 MRYDFGGTYILKYEE---GLFAGGPMidkkgwNALPDLRFNSGIgaNFPQWWNLDAYLSANYIDSQSQDyVNGQEEGHIA 791
Cdd:PRK13483  535 STLSLSGNYTYTDSEqksGAYKGSPL------NQLPKHLFQASL--NWEPTDRLNSWARVNYRGEESQP-TTGPSSSSFI 605

                         730       740       750       760       770       780
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1752263663 792 --SNTVWNLNVAVDTGWNAKIQTGVKNMFNRgpslssdGFTYEEDLYGIDGRIYYIDYTQKF 851
Cdd:PRK13483  606 apSYTFLDLGANYQLTDNLKLSAGIYNLFDK-------EINYEEYGYVEDGRRYWLGMTYSF 660
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
54-820 8.69e-14

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 75.30  E-value: 8.69e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  54 TP--VVSVSKAQIEQSGQQTVADYLKQASYNSFGGYSPSSGDSYQsqgtvgLRGLgSTRTLVLLNGKRIAGSptmggtsi 131
Cdd:COG4774     9 TPqsVTVVTRELIEDQGATSLADALRNVPGVTFGAGEGGNGDSFS------IRGF-SASGDIYVDGLRDPGQ-------- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 132 nlNTIPMAAVERVEVnLDG-GSALYGSDAIGGVINVILKE-GFEGLT-FQGRIGSpteegGDEQSGSI-VSGITGDKGS- 206
Cdd:COG4774    74 --YRRDTFNLERVEV-LKGpASVLYGRGSPGGVINLVTKRpTDEPFTeVTLTYGS-----DGQRRATLdVNGPLGDDLAy 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 207 -LMMVYEH---DVKDViyYKDRDYLakqgaeAPSIygrNIKGVDATTGktvtrTLDGI-----DCANTGAGFVPVGTACR 277
Cdd:COG4774   146 rLNGMYRDsdsYRDGV--DNDRWGI------APSL---TWRLGDRTRL-----TLDYEyqdddRTPDYGVPAVANGRPVD 209

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 278 FD----FAQIAAKTASRTrDTVYVNGRYHINDNVDFVPQLIGSRVTSFGRFApaagaftvdgstpesaavlsanNFSTAK 353
Cdd:COG4774   210 VDrstfYGQPDDYSDSET-DSATLRLEHDFNDNWTLRNALRYSDYDRDYRNT----------------------YPTGGN 266

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 354 AATVYYRFNNVGPRDNDVTdmtgNMNLGFEGTVPTEAVgDLEWNAGYMYSKTDNRsngsgyvlepavqtqvnsgkfiNGS 433
Cdd:COG4774   267 ATGTVTRSAYRRDQDNDTL----SNQTDLTGKFDTGGV-KHTLLAGVEYSREDSD----------------------NAR 319

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 434 FSDAATkdlsydtsrtskmdffqwygglgwemgelpAGPVSWYlGAEYNDWVYSDTYDSQSEAGNVlgssgnsgsgvrDV 513
Cdd:COG4774   320 YSGGGT------------------------------APTVNLY-NPVYGAPVTGPTLGGADNDSRT------------DT 356

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 514 FATYIESLIPITEQIELNLAGRYD----KYSDFG----------SAFSPKASLRYQPLDQLMFRTSWSQSFRAPGlddly 579
Cdd:COG4774   357 TGLYLQDTISLTDRWSLLAGLRYDrfdtDYTDRTtgattssyddSAFSPRAGLVYKPTPNLSLYASYSTSFNPGG----- 431

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 580 aadsfsadfakdyvgcQANGIANcseaqydttrkANKNLKEETANTFTIGAAYNPLDN-LNLSLDYYYIKIDDVIQLATT 658
Cdd:COG4774   432 ----------------GAPSLSN-----------AGQALDPEKSRQYEVGVKWDLLDGrLSLTAALFRIEKTNVRTTDPA 484

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 659 QTQFYqelntgsnpnvirdangdvemvyagmVNLGQLKTSGIDFKADYK--YDFNFFtmrydFGGTY----ILKYEEGLF 732
Cdd:COG4774   485 NPGVY--------------------------VQTGEQRSRGVELEATGEltPGWSVL-----AGYTYldaeITKSANAAN 533

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 733 AGGPMIDkkgwnaLPDLRFNSGIGANFPqWWNLDAYLSANYIDSQSQDYVNGQEeghIASNTVWNLNVAVDTGWNAKIQT 812
Cdd:COG4774   534 VGNRLPN------VPRHSASLWTTYDLP-LPGLTLGGGVRYVGSRYADAANTVK---LPSYTRFDAGASYRLNKNLTLRL 603


                  ....*...
gi 1752263663 813 GVKNMFNR 820
Cdd:COG4774   604 NVNNLTDK 611
PRK13513 PRK13513
ligand-gated channel protein;
23-204 1.72e-11

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 67.87  E-value: 1.72e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  23 SVSAEEGQNVEKLQKIKVTGSRISRvDVEGATPVVSV-SKAQIEQSGQQTVADYLKQA-SYNSFGGYSPSSgdsyqsqgt 100
Cdd:PRK13513   23 AYAAEKTNTATPTDTMVVTASGFQQ-RIQDAPASISVvTREQLENKAYRDVTDALKDVpGVVVTGGGSTSD--------- 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 101 VGLRGLGSTRTLVLLNGKRIAGS---PTMGGTSINLN-TIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGFEGLT 176
Cdd:PRK13513   93 ISIRGMAAKYTLILVDGKRVDTRstrPNSDGSGIEQGwLPPLAAIERIEVVRGPMSSLYGSDAMGGVINIITRKVQKEWH 172

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1752263663 177 FQGRIGSPTEE---GGDEQ------SGSIVSGITGDK 204
Cdd:PRK13513  173 GSLRADATLQEdskSGDIFqtnayaSGPLIDGLLGLK 209
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
103-183 6.49e-11

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 65.78  E-value: 6.49e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 103 LRGLGSTRTLVLLNGKRIAGSPTMGgtSINLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEGFEGLTFQGRIG 182
Cdd:PRK10641   88 IRGTNSSHVLVLIDGVRLNQAGISG--SADLSQIPISLVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDKPGTTLSAGWG 165


                  .
gi 1752263663 183 S 183
Cdd:PRK10641  166 S 166
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
33-194 1.81e-10

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 64.64  E-value: 1.81e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  33 EKLQKIKVTGSRISRVDVEGATPVVSVSKAQIEQSGQQTVADYLKQASynsfgGYSPSSGDSYQSqgtVGLRGLGSTRTL 112
Cdd:PRK13484   28 KKEDTLVVTASGFTQQLRNAPASVSVITSEQLQKKPVSDLVDAVKDVE-----GISITGGNEKPD---ISIRGLSGDYTL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 113 VLLNGKRIAG--SPTMGGTSINLNTIPMA-AVERVEVNLDGGSALYGSDAIGGVINVILK----EGFEGLTFQGRIGSPT 185
Cdd:PRK13484  100 ILVDGRRQSGreSRPNGSGGFEAGFIPPVeAIERIEVIRGPMSSLYGSDAIGGVINIITKpvnnQTWDGVLGLGGIIQEH 179


                  ....*....
gi 1752263663 186 EEGGDEQSG 194
Cdd:PRK13484  180 GKFGNSTTN 188
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 24-820 2.60e-10

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 64.15  E-value: 2.60e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  24 VSAEEGQNVEKLQKIKVTGSRISRVDVEgaTP--VVSVSKAQIEQSGQQTVADYLKQASYNSFGGYSPSSGDSYQSqgtv 101
Cdd:COG4773    37 VTGTAEGTGGYTAKSSSTATKLDTPLRE--TPqsVSVVTRQLIEDQGATTLDDALRNVPGVTVSSYDGGGRDSFSI---- 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 102 glRGLGSTRTLVllNGkriagsptMGGTSINLNTIPMAAVERVEVnLDG-GSALYGSDAIGGVINVILKegfegltfqgr 180
Cdd:COG4773   111 --RGFSIDNYLR--DG--------LPLGGFGGGQPDTANLERVEV-LKGpAGLLYGAGSPGGLVNLVTK----------- 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 181 igSPTeeggDEQSGSIVSGItgdkGSlmmvyehdvkdviyykdrdylakqgaeapsiYGRNIKGVDattgktVTRTLDgi 260
Cdd:COG4773   167 --RPT----AEPQGEVSLSA----GS-------------------------------WDTYRATAD------VGGPLN-- 197

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 261 dcANTGAGFvpvgtacRFDFAQIAAKT----ASRTRDTVYVNGRYHINDN----VDFvpQLIGSRVTSFGRFAPAAGAFT 332
Cdd:COG4773   198 --EDGTLRY-------RLNAAYEDGDSfrdgVDNRRTLIAPSLDWDLTDDttltLGA--EYQDDDSTGDRGFLPLDGTLL 266

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 333 vdgSTPESAAVLSANNFSTAKAATVYY----RFNNvgprdndvtdmtgnmnlgfegtvpteavgDLEWNAGYMYSKTDNR 408
Cdd:COG4773   267 ---DLPRSTNLGEPWDYYDTETTTLFAelehRFND-----------------------------DWSLRANARYSDSDRD 314

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 409 SNGSGyvlepavqtqvnsgkfiNGSFSDAATKDLS---YDTSRTSKMDFFQWYGglgweMGELPAGPVS--WYLGAEYND 483
Cdd:COG4773   315 GRSAY-----------------AYGAPDAATGTLTryaSARDGDSRSDSLDANL-----NGKFETGGLEhtLLVGADYSR 372

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 484 WvYSDTYDSQSEAGNVL----------GSSGNSGSGVRDVFATYIESLIPITEQIELNLAGRYDKYSDFG---------- 543
Cdd:COG4773   373 Y-DSDSDSATAGTINIYnpvygnlpepDFDASDTDTTTRQTGLYAQDQISLTDRLSLLLGGRYDWYETDStnrlggstts 451

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 544 ---SAFSPKASLRYQPLDQLMFRTSWSQSFRAPglddlyaadsfsadfakdyvgcqaNGIANcseaqydttrkANKNLKE 620
Cdd:COG4773   452 yddSAFTPRAGLVYDLTPGLSLYASYSESFEPQ------------------------SGADN-----------NGNPLDP 496

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 621 ETANTFTIGAAYNPLDN-LNLSLDYYYIKIDDVIQLATTQTQFYqelntgsnpnvirdangdvemvyagmVNLGQLKTSG 699
Cdd:COG4773   497 ETGKQYEAGVKGELFDGrLNATLAVFDITQKNVATTDPDNPNFY--------------------------VQVGEVRSRG 550

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 700 IDFKADYKYDFNFftmRYDFGGTYI-LKYEEGlfaGGPMIDKKGWNAlPDLRFNSGIGANFPQWW--NLDAYLSANYIDS 776
Cdd:COG4773   551 VELELSGELTPGL---NLIAGYTYTdAKITKD---ADALEGKRLTNV-PRHTASLWTTYRFPSGAlkGLGLGGGVRYVGE 623

                         810       820       830       840
                  ....*....|....*....|....*....|....*....|....
gi 1752263663 777 QSQDYVNGQEeghIASNTVWNLNVAVDTGWNAKIQTGVKNMFNR 820
Cdd:COG4773   624 RYGDAANTFT---LPSYTLVDAGARYDLGKNWTLQLNVNNLFDK 664
PRK13486 PRK13486
TonB-dependent receptor;
40-170 5.53e-10

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 63.12  E-value: 5.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  40 VTGSRISRVDVEGATPVVSVSKAQIEQSGQQTVADYLKqasynSFGGYSPSSGDSYQSQGTVGLRGLGSTRTLVLLNGKR 119
Cdd:PRK13486   30 VSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALR-----SVEGVDVESGTGKTGGLEISIRGMPASYTLILIDGVR 104

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1752263663 120 IAGSPTM---GGTSINLNTIP-MAAVERVEVNLDGGSALYGSDAIGGVINVILKE 170
Cdd:PRK13486  105 QGGSSDVtpnGFSAMNTGFMPpLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRK 159
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 90-851 8.14e-08

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 55.92  E-value: 8.14e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663  90 SSGDSYQSQGTVGLRGLGSTRTLVLLNGKRIAGS-----------PTMGGTsinlNTIPMAAVERVEVNLDGGSALYGSD 158
Cdd:PRK13528   86 SASGTRGNNRQIDIRGMGPENTLILIDGVPVTSRnsvryswrgerDTRGDT----NWVPPEMVERIEVIRGPAAARYGSG 161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 159 AIGGVINVILKEGFE----GLTFQGRIGSPTEEGGDEQSGSIVSG-ITGDkgSLMMvyehdvkdviyykdrdylakqgae 233
Cdd:PRK13528  162 AAGGVVNIITKRPTNdwhgSLSLYTNQPESSKEGATRRANFSLSGpLAGD--ALTM------------------------ 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 234 apSIYGrNIKGVDAttgktvtrtlDGIDCaNTGAGFVPVgtacrfdfaqiAAKTASRTRDtvyVNG--RYHINdnvdfvP 311
Cdd:PRK13528  216 --RLYG-NLNKTDA----------DSWDI-NSSAGTKNA-----------AGREGVRNKD---INGvlSWKMT------P 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 312 QLIGSRVTSFGR----FApaagaftvdGSTPESAAVLSANNFSTAKAAT-VYYRfNNVGprdndvtdMTGNmnlgfegtv 386
Cdd:PRK13528  262 QQILDFEAGYSRqgniYA---------GDTQNSNSSAVTESLAKSGKETnRLYR-QNYG--------LTHN--------- 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 387 pteavGDLEW---NAGYMYSKTDNrsngsgyvlepavqTQVNSGkfINGSFSDAATKDLSYDTSRTSkmdffqwygglGW 463
Cdd:PRK13528  315 -----GIWDWgqsRLGFYYEKTNN--------------TRMNEG--LAGGGEGRITADQTFTTSRLE-----------SY 362

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 464 EM-GELPAgPVSWY------LGAEYNDWVYSD------TYDSQSEAGNVLGSSGNSGSGVRDVFATYIESLIPITEQIEL 530
Cdd:PRK13528  363 RTsGELNV-PLNWLfeqtltVGAEWNRDELNDpsstslTVKDGDIGGISGSAADRSSKNKSEISALYVEDNIEPVPGTNL 441

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 531 NLAGRYDKYSDFGSAFSPKASLRYQPLDQLMFRTSWSQSFRAPgldDLYAADsfsadfaKDYV------GCQANGIANCS 604
Cdd:PRK13528  442 IPGLRFDYHSEFGSNWSPSLNLSQELGDYFKVKAGIARAFKAP---NLYQSS-------EGYLlysrgnGCPKDITSGGC 511

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 605 EAQydttrkANKNLKEETANTFTIGAAYNPlDNLNLSLDYYYIKIDDVIQlATTQTQFYqelnTGSNPNVIRDANGDVEM 684
Cdd:PRK13528  512 YLV------GNKNLDPEISVNKEIGLEFTV-DDYHASVTYFRNDYQNKIV-AGDDVIGR----TASGAYILQWQNGGKAV 579

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 685 VYAGMVNLgqlktsGIDFKADykydfnffTMRYDFGGTYILKYEEGLfAGGPM--IDKKGWNALPDLRFNSGIGANFPqw 762
Cdd:PRK13528  580 VEGLEGNL------LVPLMKD--------RLNWNTNATYMITSEQKD-TGNPLsvIPKYTINSTLDWQITQALSANVN-- 642

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 763 WNLDAYLSANYIDSQSQDYVNGQEEGHIASNTVWNLNVAVDTGWNAKIQTGVKNMFNRGPSLSSDGF-TYEEdlygiDGR 841
Cdd:PRK13528  643 WTLYGKQKPRTHAESRSEETGGLSGKELGAYSLVGVNVNYDINKNLRLNVGVSNLFDKQIYREGEGAnTYNE-----PGR 717

                         810
                  ....*....|
gi 1752263663 842 IYYIDYTQKF 851
Cdd:PRK13528  718 AYYAGVTASF 727
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 100-654 4.53e-07

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 53.88  E-value: 4.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 100 TVGLRGLGSTRTLVLLNGKRIAgSPTMGGTSINLNTIPMAAVERVEVN------LDGGsalygsdAIGGVINVILKEGFE 173
Cdd:TIGR01782  64 YVSVRGLGPSYNRTTLNGRTIA-STDSGGRAFSLDLLPSELVSGVEVYktptadMDEG-------GIGGTVDLRTRSPFD 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 174 gltFQGRIGSPTEEGGDEQSGSiVSGITGdKGSLMMVYEHDVKDV-----IYYKDRDYLAKQ-GAEAPSIYGRNikgvda 247
Cdd:TIGR01782 136 ---YDGRTLSGSAQGGYNDLAG-KDKPGP-RGAASYSWTFGDGQFgvllsASYQKRDFAEDNvETENWGTYTSA------ 204

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 248 ttgktvtrtldgiDCANTGAGFvPVGtacrfdfAQIAAKTASRTRDTVYVNGRYHINDNVDFVPQLIGSRV-TSFGRFAP 326
Cdd:TIGR01782 205 -------------DGGAQGLYF-PRG-------VRYRSYRNDRERKGVNGSLQWRPSDALELYLDTLYSKYdDDETRQQI 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 327 AAGAFTVDGSTPESAAVLSANNFSTAKAATVYYRFNNvgpRDNDVTDMTGNMNLGFEGTVPteaVGDLEWNAGYMYSKTD 406
Cdd:TIGR01782 264 EFRTLNGGSTVITSNQTATSGALVQGTVANLQILVEA---RYNEEKETTTSLTLGGEWTGD---RWTLDGDLGYSKATRD 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 407 -----------------------------------------NRSNGSGYVLEPAVQTQVNSGKF--INGSFSD------- 436
Cdd:TIGR01782 338 rpdrvtrfftaptpgydfdyrggptltlgtpadgddasnytNPANGELRRTQISYQKAEDSEDAaqLDATFDGpftslkf 417

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 437 ---AATKDLSYDTSRTSKMDFFQWYG-------------GLGWEMGELPAGPVSWYLGAEYNDWVYSDTYDSQSEAGNvl 500
Cdd:TIGR01782 418 gvrYRRRDKTNRGSRYRRSIIGATGAsglagvpsdlagaGLDGGLGGPLTGWDPADLDAFLNAARGDAAGGGTYTYAS-- 495

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 501 gsSGNSGSGVR-DVFATYIESLIPITEQIELNLAGRYDK-------------YSDFGSAFS------------PKASLRY 554
Cdd:TIGR01782 496 --TAPNTYTVTeDTTAAYAMANFDTGLRLRGNVGVRYERtdqtsdgwqsqpaANGTGSVLVpvsadrdytdvlPSLNLAY 573

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 555 QPLDQLMFRTSWSQSFRAPGLDDLYAADSFSADfakdyvgcqangiancSEAQYDTTRKANKNLKEETANTFTIGAAYNP 634
Cdd:TIGR01782 574 DLTDDLVLRFAASKTITRPDFGDLAANTSLSDD----------------GTGGTVTVSGGNPDLKPYESDNLDLSLEWYF 637

                         650       660
                  ....*....|....*....|
gi 1752263663 635 LDNLNLSLDYYYIKIDDVIQ 654
Cdd:TIGR01782 638 GPGGLLSAAVFYKDIKNFIV 657
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
103-669 3.35e-06

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 50.80  E-value: 3.35e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 103 LRGLGSTRTLVLLNGKRIAG--SPTMG-----GTSINLNTIPMAAVERVEVNLDGGSALYGSDAIGGVINVILKEG---F 172
Cdd:PRK13524  101 IRGMGPENTLILIDGKPVSSrnSVRYGwrgerDTRGDTNWVPPEMIERIEVLRGPAAARYGNGAAGGVVNIITKKPtgeW 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 173 EG-LTFQGRIGSPTEEGGDEQSGSIVSGITGDKGSLmmvyehdvkdviyykdRDY--LAKQGAEAPSIygrNIKGVDATT 249
Cdd:PRK13524  181 HGsWNTYFNAPEHKAEGATKRTNFSLSGPLGDELSF----------------RLYgnLNKTQADAWDI---NQGHQSART 241

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 250 GktvtrtldgidcanTGAGFVPVGtacrfdfaqiaaKTASRTRDtvyVNG--RYHINDNvdfvpQLIGSRVtSFGRfapA 327
Cdd:PRK13524  242 G--------------SYAGTLPAG------------REGVINKD---INGllRWDFAPL-----QSLELEA-GYSR---Q 283

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 328 AGAFTVDGSTPESAAVLSANnfstakaatvYYRFNNVGPRDNDVTDMTGNMNLGFEGTVPTEavgdlewnagymYSKTDN 407
Cdd:PRK13524  284 GNLYAGDTQNTNSDALVKSL----------YGKETNRMYRQNYALTHRGGWDNGVSTSNYAQ------------YEHTRN 341

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 408 RSNGSGyvLEPAVQTQVNSGkfiNGSFSDAATKDLSYDtsrtSKMD-FFQWYGglgwemgelpagPVSWYLGAEYNDWVY 486
Cdd:PRK13524  342 SRLPEG--LAGGTEGIFNEK---ATQFSTIDLDDVMLH----SEVNlPFDLLV------------NQTLTLGTEWNQQRM 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 487 SDTYD---SQSEAGNV--LGSSGNSGSGVRDVFATYIESLIPITEQIELNLAGRYDKYSDFGSAFSPKASLRYQPLDQLM 561
Cdd:PRK13524  401 KDPSSntqALTSGGAIpgVSATGRSPYSKAEIFSLFAEDNMELTDSTMLTPGLRFDHHSIVGNNWSPSLNLSQGLGDDFT 480

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1752263663 562 FRTSWSQSFRAPgldDLYAADSfsadfakDYV------GCQANGIANCseaqYdttRKANKNLKEETANTFTIGAAYNPl 635
Cdd:PRK13524  481 LKMGIARAYKAP---NLYQTNP-------NYIlyskgqGCYASAGNGC----Y---LQGNDDLKAETSVNKEIGLEFKR- 542

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|..
gi 1752263663 636 DNLNLSLDYYYIKIDDVI--------QLATTQTQFYQELNTG 669
Cdd:PRK13524  543 DGWLAGLTWFRNDYRNKIeagyvpvgTNSVGKTDIYQWENVP 584
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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